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Query: VFG000853(gi:4689215) (aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214)] [Escherichia coli str. 042], from VFDB

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MWQIKTSLTAVAYSVMMTCTLLHVEDVIARTYSFNSSLLSGGVKGVDLTVFEEGGQLPGIYQTDIILNGSRVDSLEMPFHTEKDENGRPYLKTCLTQEMLARYGVKTEEYPALFRSLGGGSDTSGERGVCADLSAIPQATENYQFAAQQLVLGIPQVALRPLLRGIAPEVLWDDGIPAFLLNWQANAGRSEYRGYIKDVEDYFWSSLEPGINIGSWRIRNLTTWNKSSGQSGKWESLYIRAERGLNSLKSRLTLGENYTPSDIFDSVPFRGGMLSSDESMVPYNQREFAPVVRGIARTQARIEVRQNGYLIQSQTVAPGAFALTDLPVTGSGSDLQVTVRESDGTVQVFTVPFTTPAIALREGYLKYNVMAGQYRSSDDAVEDSTLGQVMGMYGLPWGLTVFGGLQGAEHYQSAALGLGWSLGKLGAVSLDTIHSRGQQKGYNYETGNTWRIRYNKSFELTGTSFTAASYQYSSSGYHTLSDVLETYRDDGRFAYRSTDSRTSRTTVNLSQSLGRWGYLGLNGSRDEYRDRPHQDYIGASYGASWNRMSLSVNWSRNHSTRGYYGSKSRTEDSISIWMSIPLESWLGRSDNNISATAQMQRSTEQNTRYELGLNGRAFDRRLFWEVHEQMVSGSEYNTGTSRLNLRWSGTYGELAGMYSYSSNMRQINAGMSGSMVAHGEGVTFGQRAGDTVTLIAAPGVSGASVGDWPGVRTDFRGYALAGYASPYQENVITLDPTTFPEDAEVPQTDSRVVPTKGAVVRAGFRTRVGGRALVSLTRQDGSSLPFGAIVTLEGKPGETSGSAGVVDDKGRVYLSGLSETGKLKAQWGENSLCHADYRLPEEKGPAGIFLTRTVCMLast
1 -123.000PF00577.18; A8AF47_CITK8/198-751; Outer membrane usher protein  ali follow..  30  1...........................................................................................................................................................................................................YLGVNAGLSWDGWLLKHIGNLNWQQQGKAHWNSNQTYLQRPIPQINSIVSGGQIFTNGEFFDTIGLRGVNLATDDNMFPDGMRSYAPEIRGVAQSNALVTVRQGNNIIYQTTVPPGPFTLQDVYPSGYGSDLEVSVKEADGSVQVFSVPYASVAQLLRPGMTRYALSAGKVDD-SSLRNKPMLYQATWQQGLNNLFTGYAGVTGFDDYQAFLLGTGMNTG-VGALSFDVTHSRLKSDT-LDEHGQSYRATFNRMFTETQTSIVLAAYRYSTKGYYNLNDALYAVDQENHNSNYTVWRQKNSMTFTVNQNLPDWGGFYLSGRVSDYWNRSGTEQYQLSYNNMFGRLSWSVSAQRVYTPDS---SGHRRDDRVSLNFSYPLWFG---ENRTANLTSNTSFNNSHFASSQIGVNGSLDENNLNYGVSTTTATGG---QHDVALNGSYRTPWTTLNGSYSQGEGYRQSGLGASGTLIAHQHGVVFSPESGTTMALIEAKDAAGAMLPGSPGTRIDSNGYAILPYLRPYRINAVEIDPKGSNDDIAFDRTVAQVVPWEGSVVKVAF............................................................................................ 554
2 -50.400PF13954.4; A7MEY2_CROS8/8-155; PapC N-terminal domain  ali follow..  37  1................................YFNPALLDPSQGKTDLTLYEKGPAAPGKYRVDVYINNERIDTREIEFTLKTASDGSSTLQPCFTLEDLKSLGVKTDEFDALD-----------ADAKCVDLSAIPSASARFDVGRQQLQLSIAQSALGQVPQGYIPPEEFNEGINALLFNYSVNG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 148
3 -27.400PF13953.4; A6TGZ4_KLEP7/658-724; PapC C-terminal domain  ali follow..  35  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MLTLRT-RNGVVPFGALVTLDND-HGSASRSNIVGDEGQVYLTGLQKKGQLLARWGESEQCTVHYDF................. 67
4 -11.100PF16967.3; W0L6Q3_9ENTR/251-319; Fimbrial, FimD or usher-like  ali follow..  15  5...................................................................................................................................................................................................................................................................................................MVLFATADGDYEFYRDGRLIRRLPAVIGRNEIDYSQLPGGFYSVEIRLVNRSGQVVS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 61
5 -7.580PF11625.6; C5AWU9_METEA/4-85; Protein of unknown function (DUF3253 topsan)  ali follow..  18  4................................................................................................................................................................................................................................................IEETMLRLVSERGADKTCCPSEIARALG-------------PDGWSPLMQPVRRVAVKAGRVQILRKGKPVEDPDDFRGIYRLS.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 80
6 -6.450PF00852.17; H3DEF3_TETNG/181-360; Glycosyltransferase family 10 (fucosyltransferase) C-term  ali follow..  15  3...................................................................................................................................................................................................................RTVCWIVDTKEMVNNSTQSYETYVALLKYIQVDLFDISSDEAKGEGYLS--TIKSCKF---YLSFESFVHRD-ALGTVPVALGPPRKN------------YENFVPGSSFHVNDFSDAAALAEHLQSLDRDEQAYLRY........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 133
7 -6.350PF11725.6; Q887C9_PSESM/17-1794; Pathogenicity factor  ali follow..  11 1044............................................................................................................................................................................ENPTKKLLGTLKHQGLKLSHQKADIPLGQRRDASEDHGLSKAR--ALDLVTLKSLGALLDQVEQLPP--QSDIEPLQKKLALRDVTYGENPVKVVTDMGF---TDNKALESGYESVKTFLKSFKKADHAVSVNMRAAT--QAELAG---KFKSMLKQLEHGDDEVGLQRSYGVNLTTPFATGLWPTAGATGNRNYILNAERCEG-----------------GVTLYLISEGAGNV-----SGGFGAGKDYANNPARSVDVGNNRTLTPNFRLGVDVTATVAASQ---RAGVVFNVPDVDDLFEGQLNPLQVLKK-----AVDHESYEARRFNFDLTAGGTADIRAGINLTEDRDPNADPNSDSRGGFAANITVNLMTYTDYSLTQKNDKTELKEGGKNRPRFLNNVTAGGQLRAQIGGSHTAPTGTPASAPGPTPASQTAANNLGGALNFSVENRTVKRIKFRYNVAKPITTEGLSKLSKGLGEAFLDNTTKAKLA-ELADPLNARYTGKKPDEVIQAQLDGLHRASANKHSVMDNARFETSKTNLSGLSSESILTKIMSSVRDASAPGNATRVAEFMRQDPKLRAMLK-EMEGSIGTLARVRLELEDRNEMRIKRLVVFHTATQAENFTSPLVSYNSGANVSVTKTLGRINFVYGADQDKPIGYTFDGELSRPSASLKEAA.. 1767
8 -6.240PF06016.9; VP1_AQRVC/1-1298; Reovirus core-spike protein lambda-2 (L2)  ali follow..  11  466............................DRERMARRDLFRRLRAPADRSAIKDRAVFDFLASLVNPTTANPVTSFSMAYLGASSAHASGSIPGLPIPRRIVQFGYDVVH--GSLLDLSRAVPTGTFGLVYADLDQVEDAGTDMPAAN-RAAIAMLGTALQMTTAG---------GVSVLKVNFPTRAFWTQVFNLYATHATTLHL-------VKPTIVNSSEVFRQSNGALRSTTALQRALLSLYARNAA----------DRAVTHIPFFGVPDDGTSDLGIDAVRLFDPMF--------------------DAVANLPSNALASLVSRVVPSSIMFTRVPSNGPVSTTIYGKRTFLSNRRRARLRDITTTLVHQRRFTTPPTFTLFSSEAVPVTTLVAAGYNSFISEQTRNPNLLGTGPECRILSLIPSDARPCAELMASFDPALTAYVQGDYSTAAFWNGIRCDSATAIFT--GAAAAAAGTDLIAFVQQLIPRIVAAGGTRMWLQLNTPLYE-DLIDIDLRDRVY-GGERVEPYADAAALSWHTLSPTCDWLPYIIGVGSPLNLSDINTAISYSRLTPILHIDTTTPPLRVNPVPTPLNQQCAIRITSLDPAAVLSVQHN-GVEVIGGTPGNVISVAGAAALQYILANQEFLLQFTPTLPGIFDVFLTTLGQPPVPRGSFTITPPPTTVVLNMPPPGQLDFTDVGNDARITCDPYYQLAVCIFKDGQYVRVNPEKASVVTNAPNRDLHFVLDLADNHVLLYPSGLGDRIAFPIVDIYRIAFPRNTPVRASLPYTGGG---AHLTSGGNPFMSLTTPPAVLPAGV............................. 1271
9 -6.030PF15976.3; A6T574_KLEP7/715-807; CS1-pili formation C-terminal  ali follow..  15  3...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PGNVAVIEPEVKQMVTVSGRIRAEDGTLLA-NARIN-------NHIGRTRTDENGEFVMDVDKKYPTIDFSYGGNKTCEVA--LELSQARGAVWVGDVVC. 92
10 -5.650PF08770.9; B8GSV5_THISH/6-100; Sulphur oxidation protein SoxZ  ali follow..  10  7..............................................................................................................................................................................................................................................................GDTTTVRALMSHPMETGQRKNKAGEPIP-------------AHYIKEVVAEVKGKNVLTAAISRNPYLSFQFTGAAAGDTLKISWVDNKGEADS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 91

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.