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anford Burnham Prebys Medical Discovery Institute

Query: TM0020 TM0020 281901 Purified-2001-08-24, from T.maritima

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIELDYLTIAFGGAIGAVLRYLVSRTINSLLPFSYIPLGTIIVNSVGSFFLSFLMFAAIEKVPLSKEAILFFGTGLLGAFTTFSTFTYETLSLIEESPARGVAYALANLLFAFTCAYFGMILGRGKVLast
1 -10.000 VFG045604(gi:52843080) (lpg2885) Dot/Icm type IV secretion system effector [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  14  1..................MEFFMWDKIKEWYKNN---KSYLTMLLIGSAVVGLSVTFL-----------ALFFPPVLAAFASISIFGMAPLAFLTSLHLPLAVLTLGCIVAAFGAILGGLVAWKQSI 97
2 -6.430 VFG001395(gi:15608948) (mgtC) Possible Mg2+ transport P-type ATPase C MgtC [MgtC (VF0289)] [Mycobacterium tuberculosis H37Rv]  ali follow..  17  9FALRLAVGVGCGAIIG----------LERQWRARMAGLRTNALVATGATLFVLYAVATEDSSPTRVASYVVSGIGFLGGGV-----------ILREGFNVRGLNTAATL----CSAAVGVLAASGHL 111
3 -6.310 VFG000575(gi:16767048) (mgtC) Mg2+ transport protein [MgtBC (VF0106)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  20  10YILNLLAAMLLGALIG----------AERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGV-----------IMREGMNVRGLNTAATL----CSAGIGVLCGLGQF 112
4 -5.680 VFG002178(gi:21693307) (cylI) cytolysin immunity protein [Cytolysin (VF0356)] [Enterococcus faecalis str. MMH594]  ali follow..  12  35.......................................SIFVHELGHLAFGLFNKVRPESLIFGFKIRLNTQWGFFGGLFRYKPTTFNNKKIL----RLLTGGPIFSLFFTLTFFVKIDFFQYFSL 127
5 -5.650 VFG002119(gi:52841585) (sidG) Dot/Icm type IV secretion system effector SidG [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  14  1......MFLPKGGQKMSRSKDEVLEANDSLFGITVQTWGT--------------------NDRPSNGMMNFADQQFFGGDVGHASINMK-LPVTDKTKQWIEKYCYSQ................... 81
6 -5.610 VFG041236(gi:52840351) (ceg4) Dot/Icm type IV secretion system effector Ceg4 [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  22  264MGAFAGIGFGFGFALGVTL---VATGVFA-------PSG---VGLLGALTLGAISGT------------TAALSSAIGFVVAEGT.......................................... 324
7 -5.450 VFG041326(gi:52842537) (lpg2327) Dot/Icm type IV secretion system effector [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  13  241.....................................WGDYLKNLLKCLGNAVITVFTFGYQQ--------------GFFAYARPDSAKAVEKAEED.............................. 286
8 -5.380 VFG001795(gi:37572662) (cba) c protein beta antigen [  ali follow..  19  10..................MRYSIRK----------FSVGVASV-AVASLFMGSVAHASELVKDNSVKT------------TEVAAKPYPSMAQTDQGN............................. 66
9 -5.060 VFG002296(gi:505281) (C3) exoenzyme C3 [C3 toxin (VF0387)] [Clostridium botulinum D str. 1873]  ali follow..  124......IMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLGYISTSLMNVSQFAGRTKFKVAKGSKAGYIPISAFAGQLEMLLPRHSTYHIDDM...................... 228
10 -4.950 VFG002294(gi:3478671) (C2I) C2 toxin (component-I) [C2 toxin (VF0384)] [Clostridium botulinum C str. 203U28]  ali follow..  22  338......................................GKEIEN--LSFSSTSLKSTPLSFSKSRFIFRLRLSEGTIGAIYGFSGFQDEQEILLNKNSTFKIFRI...................... 403

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I, Jambon M, Godzik A. New avenues in protein function prediction. Protein Sci. 2006 Jun;15(6):1527-9.