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Query: TM0024 TM0024 281905 Purified-2001-08-24, from T.maritima

Results of FFAS03 search in PfamA26U
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MMSRLVFALLLFPVFILAQNILGNASFDEPILIAGVDIDPPAEDGSIDTGGNWVFFTNSNGEGTARVENGVLVVEITNGGDHTWSVQIIQAPIRVEKLHKYRVSFRAKASSQKNIGVKIGGTAGRGWTAYNPGTDESGGMVFELGTDWQKYEFEFVMRQETDENARFEFQLGRYTGTVWIDDVVMEDIGVLEVSGEENEIYTEEDEDKVEDWQLVWSQEFDDGVIDPNIWNFEIGNGHAKGIPGWGNGELEYYTDENAFVENGCLVIEARKEQVSDEYGTYDYTSARMTTEGKFEIKYGKIEIRAKLPKGKGIWPALWMLGNNIGEVGWPTCGEIDIMEMLGHDTRTVYGTAHGPGYSGGASIGVAYHLPEGVPDFSEDFHIFSIEWDEDEVEWYVDGQLYHVLSKDELAELGLEWVFDHPFFLILNVAVGGYWPGYPDETTQFPQRMYIDYIRVYKDMNPETITGEVDDCEYEQAQQQAGPEVTYEQINNGTFDEPIVNDQANNPDEWFIWQAGDYGISGARVSDYGVRDGYAYITIADPGTDTWHIQFNQWIGLYRGKTYTISFKAKADTPRPINVKILQNHDPWTNYFAQTVNLTADWQTFTFTYTHPDDADEVVQISFELGEGTATTIYFDDVTVSPQLast
1 -52.000PF03935.10; Q6FUB1_CANGA/183-684; Beta-glucan synthesis-associated protein (SKN1)  ali follow..  22  101...................................................................................................................................................................................................DTPQSALSRQARDGSYWKLVFSDEFNAEGRTFYDGEDQFWTAP--DIHYDATKDLEWYSPDASTTRNGTLQLRMDAFK----NHNLYYRSGMLQSWNKLCFTQGAIEVSANLPRVSGLWPGLWTMGNLGRPGYLPDYDFIEIHNFTTTTMNTYCGGPFQQAISAVTTLNTSWY---QYGEGSGYYQKFAIEFLNDDIQWYVGDKATWTLMNTALHANDNRHVSKEPMSIILNLGISNNWAYIDWQMIYFPVTMSIDYVRIYQPNNSVSVT................................................................................................................................................................................. 459
2 -47.600PF10287.4; C4Y1A3_CLAL4/228-458; Putative TOS1-like glycosyl hydrolase (DUF2401 topsan)  ali follow..  10  11..............................................................................................................................................................................................................TPGSADNCTFLNYYGGSG--SGVWSSAFGNSLSYANSDNSGASSSPVALSEVTIDSNTEFVVMSGLGDSSEQADCGFYREGIPAYHGWNGQEKLFVFEFEMPSSNGDMPAVWMLNAQIPSCWDTGCGEFDLFEILSTGSDKCISHLHDKQGAVNGYGGGGSSDYF--SRPTSGSLKAAVIFTESAIHIQTVDEDFGSVLSSDTVQN...................................................................................................................................................................................................................................... 229
3 -45.500PF00722.16; Q6ES25_ORYSJ/25-208; Glycosyl hydrolases family 16  ali follow..  11  1....................................................................................................................................................................................................................................................FRDECDIPWEPQNARFTDDGNGLSLSLVS--------NYSGCMLRTKKQ--FIFGSVSTLIQLV--PGNSAGTVTTYYTSSVGDNHDEIDFEFLGNETGQPYTIHTNIY------ANGVGDKEMQFKPWFNPTDGYHNYTVSWTACMIVWYIDGTPIRVFRNYE-KSNGVAFPMKRPMYGYSSIWAAEDWATQ-------GGRVKADWSK............................................................................................................................................................................................ 184
4 -10.100PF04862.7; Q8H168_ARATH/42-364; Protein of unknown function, DUF642 topsan  ali follow..  10  1......................MKGTQVIN--------KKAIPSWELSGFVEYIKSGQKQGDMLLVVPAGKFAIRLGNEAS-------IKQRLNVTKGMYYSLTFSAARTCAQDERLNISVAPDSGVIPIQ---------TVYSSSGWDLYAWAFQAESNV---AEIVIHNPGEEEDPACGPLIDGVAIK------------ALYPPRPTNKNILKNGGFEEGPYVLPNATTGVLVPPHSPLPAWSLKAIKYVDVEHFSVPQGRRAVELVAGKE------------------------SAIAQVAKTVVGK------YVL-------------SFAVGDANNACQGSMVVEAFAGKDTLKVPYESRGKG----------------GFKRASLRFVAVSTR--------------------------RVMFYSTFYSMRSDDFSSLCGPVIDDVKLLS......................................................................................................................................................................................... 321
5 -8.370PF06439.6; A6CH23_9PLAN/11-222; Domain of Unknown Function (DUF1080 topsan)  ali follow..  11  2.......................................................................................................................................................................................................................AEILLDGSREM--LDQ---------KWTYWEGPRFSSSLPIKWKVVEDPIDAGTVVMSDDPAAAGGKYGTADIVTKKK----FRDFRLHVE-----------FLVSKPGGNSGLQNRYEIQVLD--GDKTKHGMAAVINETESPYHAYNGTGKWNAYDITFRAARFKDGKLVEKPLVSMYFNGKKVHENSGLDGGNDNGFGITDTPGGIKLNIWI.................................................................................................................................................................................................................... 211
6 -8.360PF09224.6; Q62WD3_BACLD/7-224; Domain of unknown function (DUF1961 topsan)  ali follow..  10  1.................................................................................................................................................................................................................REGSLIYQNPLSSPE-DLRGWVME--------------------GKGIVRFQNGRLHMENELDAEQYGDD----AHFVYWCPETFPDGI-VVKWDFYPVREPGLCMIFFAAAGMNGEDLFERTGK--YPQYHSGDINTLHLSYFRHKHADERAFRTCNLRKSRGFHLALPPYRMKLIKDGAYVRFSINELPILEWTDDGRRFG--------------PVYGAGKIG-----RQMAPLEAAYANFEV........................................................................................................................................................................................... 218
7 -6.310PF13385.1; A0ZJ64_NODSP/406-564; Concanavalin A-like lectin/glucanases superfamily  ali follow..  10  1...............................................................................................................................................................................................................................................................KRVMQFDG--------------------FNDYVEVPYEPALNPSQFTV------------SLWAKITGEE-----GAGRSLLTSSDADEKGGYSIQANSRNKWELTVGDGNWSTIIGPDVVSNIWTHIAGTYDGNMLRLYVDGVLCGTLETAYTPNGSC------------PLRIAAAGSGGSPAS-------QMAEFRIWDVARTQAD.................................................................................................................................................................................. 157
8 -6.270PF14099.1; C7ZIC9_NECH7/22-246; Polysaccharide lyase  ali follow..  10  1.........................................................................................................................................................................................................................RKFYNPG-NLNGWDYIRR----------ENKGTVEAVTNVAYKGGNALKMTQTYTPGYTGRYHSEVDHNQGYKRGDQLF----YGFAFRLSEQWEFQPQSYNLAQANRPGASCGGDDWMPSSMLWLEGDQLVSRVVSGQYRVPDCSRDIKTFPKLAKVSAGQWHVIQASWKSDNYKIWFDGNKVLEEYNRKTTLND-----DSVFQFRIGLYANAWHDDKHMEGSQSFRQVWYDEVAI........................................................................................................................................................................................... 225
9 -6.110PF07953.7; O87710_9CLOT/811-986; Clostridium neurotoxin, N-terminal receptor binding  ali follow..  5  1.....................................................................................................................................................................................................................................................................KNVIGDGSGKNTLVEYTNDIGLIYGINNNALYLNQSNQSVSFTNDYFENGLT--YFWLRNLGKDIIK-------SKLISSKLDNCGWEIYLEDNGLVFNIIDSNGSYKKIYISDMNNSWNYIAISVDKEQLLIFVNDVLVANEDIKDILNIYSS----------NTISLVSEN------------QICIEGLSILNTN....................................................................................................................................................................................... 175
10 -6.030PF12652.2; A7B6L2_RUMGN/7-85; CotJB protein  ali follow..  15  5.........................................................................................................................................................................................................................................................LNHINAVSFAVDEVKLYLDTHPQDPDALAYFEKYSRMRNQAMKEYAMNFGPLTIDTATASCSEYWK--WI------NEPWP........................................................................................................................................................................................................................................................................................................................ 77
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alonso A, Rahmouni S, Williams S, van Stipdonk M, Jaroszewski L, Godzik A, Abraham RT, Schoenberger SP, Mustelin T. Tyrosine phosphorylation of VHR phosphatase by ZAP-70. Nat Immunol. 2003 Jan;4(1):44-8. Epub 2002 Nov 25.