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anford Burnham Prebys Medical Discovery Institute

Query: d2i6ea1 c.94.1.1 (A:16-287) Hypothetical protein DR0370 {Deinococcus radiodurans [TaxId: 1299]}, from SCOP206

Results of FFAS03 search in SCOP206
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst PYRAGWIHFTNVAPILDSLELPPGVTAITGVPTQMNAALLSGEVDIANVSAVEFIRHADTLAALPDFSVAVLGPVYSVNLFHTCPLPELRRVALTSQSAMSVALLEVLLRQKGLSPVLERAEGTAESLLAAGYDGVLRIGDDALREWYGVVGPLTPERTMTSLPHTGRGITVTDLAQEWFDLTGHPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQRHAEKLGLPERVVQHYLWNFRYHLEAPDRLGLREFADLAVPGHAELTFLast
1 -121.000d2i6ea1 c.94.1.1 (A:16-287) Hypothetical protein DR0370 {Deinococcus radiodurans [TaxId: 1299]}  ali model 3D-neighbors  100  1PYRAGWIHFTNVAPILDSLELPPGVTAITGVPTQMNAALLSGEVDIANVSAVEFIRHADTLAALPDFSVAVLGPVYSVNLFHTCPLPELRRVALTSQSAMSVALLEVLLRQKGLSPVLERAEGTAESLLAAGYDGVLRIGDDALREWYGVVGPLTPERTMTSLPHTGRGITVTDLAQEWFDLTGHPFTFAVWAYRKDNPPPAALLQAMREARRRGIGHLAEVSQRHAEKLGLPERVVQHYLWNFRYHLEAPDRLGLREFADLAVPGHAELTF 272
2 -98.300d2nxoa1 c.94.1.1 (A:5-281) Hypothetical protein SCo4506 {Streptomyces coelicolor [TaxId: 1902]}  ali model 3D-neighbors follow..  29  2RPRVGHIQFLNCLPLYWGLARTLDFELTKDTPEKLSEQLVRGDLDIGPVTLVEFLKNADDLVAFPDIAVGCDGPVMSCVIVSQVPLDRLARVALGSTSRTSVRLAQLLLSERFGVQPDYYTCPPDLSLMMQEADAAVLIGDAALRANMIDG--------------PRYGLDVHDLGALWKEWTGLPFVFAVWAARRDYVITRKVHEAFLASRNLSLEEVEKVAEQAARWEAFDEDTLAKYFTTLDFRFGAPQLEAVTEFARRVGPTTGFPA. 268
3 -77.000d2czla1 c.94.1.1 (A:3-272) Hypothetical protein TTHA1568 {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  17  2.LRLGFSPCPNDTFIFYALVHG-PLEPVLEDVETLNRWALEGRLPLTKLSYAAYAQVRDRYVALR--SGGALGRGVGPLVVARGPLQALERVAVPGRHTTAYFLLSLYAQGFVPVEVRY--DRILPMVAQGEVEAGLIIHESRFTY------------------PRYGLVQVVDLGAWWEERTGLPLPLGAILARRDLGLIRALDEAVRRSVAYALAHPEEALDYMRAHAEVIWAHVHTYVNAFSLDVGEEGERAVARLFAEAEARGLAAP. 263
4 -12.000d2ozza1 c.94.1.1 (A:1-228) Hypothetical protein YhfZ {Shigella flexneri [TaxId: 623]}  ali model 3D-neighbors follow..  15  30.LASGLKAQFDGIPFYYAHMRGADIRV---------ECLLNGVYDMAVVSRLAAESYLSQNNLCIALELGPHTYVGEQLICRKGESGNVKRVGLDSRSADQKIMTDVFFGDSDVERVDLSYHESLQRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATE----------------------AVVLTRVDDYPMQQLLRAVVDKHAL----------LAHQQRVVSGEQEPSY................................ 228
5 -7.470d2fyia1 c.94.1.1 (A:88-307) LysR-type regulatory protein Cbl {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  8.LTIATTHLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIAS--ERLSNDPQLVAFPWFR-------HSLLVPHDHPLTQISPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLADIVLSAQDS------DVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDANT-RNYVWRFLELCNAGLSVEDIKRQVMES............................................................. 220
6 -7.290d1al3a_ c.94.1.1 (A:) Cofactor-binding fragment of LysR-type protein CysB {Klebsiella aerogenes [TaxId: 28451]}  ali model 3D-neighbors follow..  13  8.LYVATTHLPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIAT--EALHLYDDLVMLPCYH-------RSIVVTPEHPLATKGSVSIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDA------DVIKTYVRLGLGVGVIASMAVDPVSDPDLVKLDANGIFHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDV............................................................ 212
7 -6.820d1i6aa_ c.94.1.1 (A:) Hydrogen peroxide-inducible genes LysR-type activator OxyR, regulatory domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  10  6PLHIGLIPTVHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDAVILALVKESEAFIEVPLFDE----------LLAIYEDHPWANREAVPMADLAGEKLLMLEMGFCFEAGADEDTHFRATSLETLRNMVAAGS--GITLLPALAVPPERKRDGVVYLPAIKPEPR----TIGLVYRPGSPLRSRYEQLA............................................................................... 200
8 -6.770d3oxna_ c.94.1.0 (A:) automated matches {Vibrio parahaemolyticus [TaxId: 670]}  ali model 3D-neighbors follow..  8.FTIATTDYAMQTILPFALPRNVSFNFLPLQHDRLSDQLTYEGADLAICRPTGPVEPLRSEILGRVLCLLSKQHPLANQEMSLDDYLSHPHAMIAISDGVKALIEQALIDKPQRKMVLRAYHLEAALAIVDTLPIIITVPADLAYLV---AERYDLVVKPLPFQFTPFDYSMISPAQEWLR........................................................................................... 199
9 -6.590d4io2a1 c.94.1.0 (A:3-248) automated matches {Adineta vaga [TaxId: 104782]}  ali model 3D-neighbors follow..  13  40......LDLIEYLRDKMGFVADVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIV----AFSNSISDNSMRILMRKGTLIDGMDRIGIRIGTAGEDYYLREISGGSRNFYPLKSRQEMYDSLLAGIIDV--SFMDIGTAEYVTNNIYCNLTLVGEDFDKSTFGI----------------------VTPKEWLYAKDLDVNILSLRETG......................................................... 230
10 -6.310d1snla_ a.39.1.7 (A:) Nucleobindin 1 (CALNUC) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  1..............................................................................................................................................................................LKEVWEELDGPKTFFILHDINSDGVLDEQELEALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNV--DTNQDRLVTLEEFLASTQR....... 96

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I, Jambon M, Godzik A. New avenues in protein function prediction. Protein Sci. 2006 Jun;15(6):1527-9.