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Query: gi|15923002|ref|NP_370536.1| putative homoserine-o-acetyltransferase (SAV0012) [Staphylococcus aureus subsp. aureus Mu50], from S.aureus

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFKEERTMTNYTVDTLNLGKFITESGEVIDNLRLRYEHVGYHGQPLVVVCHALTGNHLTYGTDDYPGWWREIIDGGYIPIHDYQFLTFDVIGSPFGSSSPLNDPHFPKKLTLRDIVRANERGIQALGYDKINILIGGSLGGMQAMELLYNQQFEVDKAIILAATSRTSSYSRAFNEIARQAIHLGGKEGLSIARQLGFLTYRSSKSYDERFTPDEVVAYQQHQGNKFKEHFDLNCYLTLLDVLDSHNIDRGRTDVTHIFKNLETKVLTMGFIDDLLYPDDQVRALGERFKYHRHFFVPDNVGHDGFLLNFSTWAPNLYHFLNLKHFKRKLast
1 -100.000[E] COG2021 Homoserine acetyltransferase  ali follow..  27  6...PDDSVGLVSPQTLHFEPLELTSGKSLAEYDLVIETYGELNSNAVLICHALSGHHHAAGDERKPGWWDSCIGPGKIDTRKFFVVALNNLGGCNGSSGPASGADFPM-VTVEDWVHSQARLADRLGIRQWAAVVGGSLGGMQALQWTISYPERVRHCLCIASAPKLSAQNIAFNEVARQAILSDPERGLKLARMVGHITYLSDDAMGAKFGRFQVESYLRYQGEEFSTRFDANTYLLMTKALDYFDPAAAHGDLVRTLEGVEADFCLMSFTTDWRFSPARSREIVDALKNVSYLEIDAPQGHDAFLMPIPRYLQAFSGYMNRIS.... 378
2 -20.800[R] KOG1454 Predicted hydrolase/acyltransferase (alpha/beta hydrolase superfamily)  ali follow..  17  79..........................................DKSPVVLLHCFDSSCL----------WRRTYP--LLEQACLETWAIDVLG--WGFSDLEKLPPCDAASKRHHLFE----LWKTYIKRPM-ILVGPSLGATVAVDFTATYPEAVDKLVLINANAYSEGTGRLKELPKSIAYAGVKLLKSFPLRLLANVLAFCSSPLSENIDWTNIGRLHCQMPW-------EDAMVDFMIS--------GGYNVASHIKHIDHKTLVVCSENDQIVSNQLSVKLLCELANAVLREVPD--GHLPHVENPKHIVKLISDFASG...... 326
3 -18.400[R] KOG4409 Predicted hydrolase/acyltransferase (alpha/beta hydrolase superfamily)  ali follow..  14  159..........................................AKYPIVLIH---------GFGAGVALWGSAIKR----AQFQTVHAFDLPG------GRSSRPKFSSDPAETEMIDSIEQWRDKMNLEKM-NLVGHSFGGYLATSYALKYPKRVENLILADPW--------GFNEMDPEFAQKLTSRQKNIFWVIQQFNPLAVLRLVGGYGPSLVRRLRPDLALKYSEDVYDYIYLANSRKCLSENLGWAKQPMSKRFHELDNPVTFIHGERSWI-DWRTTRRLFGELEHVESHIMDSA-GHHVYADDADKFVQLVIGSLKDGKTGE. 428
4 -12.900[R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)  ali follow..  16  2...................PYVTVGQENSATIDIYYEDLGA--GQPIVLIHGLNGDS-----------WEKQV---VLLNAGYRVITYDRRG--FGSSQPSSGYDYDT------FAADLHTLMTKLDLQNT-VLVGFSMGTGEVTRYLGKYSERVQKAVLMAPVPPFLLKTNDNPEGVDQSVFDGIMKAIVDDRPAYFSAFFKEFFNVDVLLGERISNEAIQASWNVAAGASAKGTLDCVPSWLT--------DFRDDLPRIDVPTLIIHGDADRILPLESTAARLPKRIKNSQLEIIPGGPHAINWTHADQVNPLLLNFLQ....... 276
5 -12.800[R] KOG2382 Predicted alpha/beta hydrolase  ali follow..  11  14........................HSDSTSSMMLANLTFGNMRSKGLILVPGLFGT--------KENW--IQVGKDLSQRLGCMVFAVENRN--HGSFSKAASMTYEE--MADDLVGFIDWVRKITGEDKV-NLHGHSMGGKAVTQLATTYSSRIKSLIVEDMSPLGYPLK---RAEYLECIKQMIATDMNKSRSEV--AELGEKVSKVLLYQFVRGNLGEDVNGKAHWICNLNV---IDETYIY-------LSHDIRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWS-NHWIHADDPKFFVDSICEFLEEPDQ... 290
6 -12.700[I] COG2267 Lysophospholipase  ali follow..  13  13..........................TTSDNTALFYRHWPALQPGVIVLFH---------RGHEHSGRLQHLVD--ELAMPDTAFYAWDARG--HGKSSGPRGYSPSLARSVRDVDEFVRFAASDSQVGLEEVVIAQSVGAVLVATWIHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHRLRGLFFINSYVKGRYLTH-------------DRQRGASFNNDPLIRAIAVNILLDLYKTSER---------IIRDAAAITLPTQLLISGDDYVVHRQPQIDFYQRLRSPKELHLLPGFYHDTL....................... 263
7 -12.500[R] KOG2564 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold  ali follow..  13  50.............................RTFRIYRTKQPEKPGPVLLLLHGGGYSALT---------WAHFC-SEVTSMIHCQCLCIDMRG--HGDSKVDDEDDLSADTLAKDIGD----LILKLYPEEVPFVVGHSMGGAIAVHFAMALVPNLIGITVIDVVEGTAMEALSIPNAIEWCIRSGQVRNVDSAKVFPNPFSISEDEESSPPGDDAADGSFKKPNTTKSTTEAAKNYTWRIDLSKSEKYWVGFSGLSDKFLNLRLPKQLLLASIDGL----DRTLTVGQMQGRFQMQVLARCGH--AVHEDHEVAEVISGYLIR...... 385
8 -11.600[I] KOG1455 Lysophospholipase  ali follow..  17  71.............................RGDTLFTQSWTPVDSALVVLLHGLNEHRYSD--------------AKQLNVNGFKVYGIDWIG--HGGSDGLHAYVPSLDYAVADLVIAENPGLPCF-------CIGHSTGGAIILKAMLKIEARVSGIVLTSPAVGVQPTYPIFGVIAPFLSFLIPRYQLSAAKKKIMPVSRDPEALL-------------------AKYSDPLVYTGFIRARTGNEILRLGAHLLQNLNRIKVPFLVMHGTADTVTDPKGTQKLYNEASSSKSIKLYDGLLHD--LLFEPERETIAGVILD....... 327
9 -11.400[R] COG1647 Esterase/lipase  ali follow..  15  14..........................................GKRAVLLLHGFTGSSADVRI------------GRFLQENNYTCYAPQYRG--HGVS-----PDLLLKTGPNDWWEDVLAAYDHLGYTEI-AVAGLSLGGLFSLKLGFSRP--LKGIIAMSTPTRMDSSSPIIQGFLDYV-----------------------------------RNYKKLEGKTPEQIDAEMVAYKDAPMNTIAKLKDEINGVVSEIDMIYAPIMVVQGEKDDMVDVSGAQLIYDTVESTKKELH-KESGHVITL-ERKDVNQAILTFLDSLDWQE. 248
10 -11.000[R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold  ali follow..  17  48..................QRLELPDGDFV-DLAWSEAPAQAQHKPRLVVFHGLEGSLNLVEAAQKRGW----------------GVVMHFRG-CSGEPNRMHRIYHS---ETEDASWFLRWLQREFGHAPTAAV-GYSLGGNMLACLLAKEGNDVDAAVIVSAPFMLEACSYHMEK---------GFSRVYQRYLLNLLKANAARKLAAYPGTLPINL--QLKSVRRIREFDDLITARIHGYADAIDYYR-QCSAMPMLNRIAKPTLIIHAKDD--FMDHQVIPKPESLPPQVEYQLTEHGGHVGFI...................... 312
11 -10.900[I] KOG4667 Predicted esterase  ali follow..  15  67.............................HNEKLVGLLHETGSTDIVVLCHGFRSNKSNQIMNNVA---------AAIQKEGISAFRFDFSGN--ESEGSFYYGNYNHE--ADDLHSVVQYFSNK---RVVPIILGHSKGGDVVLLYASKYHD-VRNVINLSGRYDLK------------------------------------------------KGIRERLGEDFLERIKQQGFIDVGDGKSGYRVTEKS-DIHEACLKIDCRVLTVHGSEDEVIPVEDAKEFAKIIPNHKLEIVEGA-NH-GYTEHQSQLVSTVMEFIKTVIVKNN 309
12 -10.600[R] KOG1838 Alpha/beta hydrolase  ali follow..  11  147..........................................RTPIAIIVPGLTSDSSIAFRLAKEGW----------------VVVQNHRG-LGGI--SLTSDCVYTAGWTEDLRKVIAHIHSQFPEAPLFAV-GTSIGANVLVKYL----EDGPNTPLIGATAVCSPWDLLICDRFINRKLVQKVYDRMLTIGLQGYAQLHHSIISRIADWEGIKK------SRSVREFD-NYATRLVAKFETTDTYYRRSSSSQYVENVAVPLLCISALDDPVCTREAIPWDECRANKNIVLATTTHGGHLAYYEGLTAWTRVVHEYFEVLLSS.. 412
13 -9.490[R] KOG4391 Predicted alpha/beta hydrolase BEM46  ali follow..  12  106..........................................DTLSCYDLDLRIPD----------------IAHRLEMVRIMI-LKCNVFMLSYRGYGASEGYPSQQGIIK-DAQAALDHLSGRTDIDTSRIVVGRSLGGAVGAVLTKNNPDKVSALILENTFTSILDMAGVLLPFLKWFIGGSGTKSLKLLNFVVRSPWKT----------------------------------------------------IDAIAEIKQPVLFLSGLQDEMVPPFHMKMLYAKAAARNFVEFPSGMHMDTWLSGGEVYWKTNLQFLEKYAPEKR 329
14 -9.440[S] COG2830 Uncharacterized protein conserved in bacteria  ali follow..  14  1.................................MKTKFYDYQGEHLILYFA---------------GW-----------------------GTPPDAVNHLILPENHDLLICYDY--QDLNLDFDLSAYRHIRLVAWSMGVWVAERVLQGIR--LKSATAVNGTGL-----------------CDDSFGIPYAIFKGTLENLTENTRLKFERRICGDK----ASFERYQLFPARPFDEIHQELTAL-----AMIQQDKRIDLIHWANAWVSSRDKIFTPANQHQYWALRCAVQEIE-----EHYVFS-RFTHWSALWDH.......... 215
15 -9.050[R] KOG4840 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)  ali follow..  10  31.......................................SNVTRSLLLFVGGLGDGLLTVPYVQELV--------NPLDEIGWSIVQVQTQSSYIGWGTGSLKRD------DEDLHKAVDYFLHIGGADF--VLMGHSTGSQNVLYYLTQSPNYLIAGIAQAPVSDREAAYQFNGKEKTKELVDWVKAEYLDKGLGNDVLPRSKVENFFGEVPTSANRCIDLTDVRGNDDFFSSD-------LSADDFAKTFGNLKEIGSTAHSQLILLMSERDEFVSPSTDKAIRPTTSNSSLSGIIPGATHNVGPKSSPELINQLITALRSFIDQ.. 316

FFAS is supported by the NIH grant R01-GM087218-01
8 5 9 5 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ma H, Xiong H, Liu T, Zhang L, Godzik A., Zhang Z. Aggregate formation and synaptic abnormality induced by DSCR1. J Neurochem. 2004 Mar;88(6):1485-96.