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anford Burnham Prebys Medical Discovery Institute
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Query: PF03529.11; M3ZUI9_XIPMA/174-274; Otx1 transcription factor, from PfamA30U

Results of FFAS03 search in SCOP206
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SPAPISPAPAPANLPDPVAPTSASCMQRSATSSSNGGAASYPVSYSQTAAAYSQGYPASASGSYFSGVECGSYLAPMHSHHHPHQLSPMTGSSMTGHPHHHLast
1 -8.590d1flca1 b.19.1.3 (A:151-306) Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF1 {Influenza C virus [TaxId: 11552]}  ali model 3D-neighbors follow..  15  3............SLVNALDKTIPLQVTAGTAGNCNNSFLKNPALYTQEVKPSENKCGKENLAFFFGTYECKLHLVAS........................ 72
2 -6.690d1ksqa1 g.23.1.1 (A:3-75) Transforming growth factor-beta binding protein-1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  1...............DQPKEEKKECYYNLNDASLCDNVLAPNVTKQECCCTSGAGW----------GDNCEIFPCPVLGTAEFTEMCPKGKG......... 67
3 -6.350d1oaca3 d.17.2.1 (A:186-300) Copper amine oxidase, domains 1 and 2 {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  11  2..VLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEG.... 96
4 -5.850d2p6ya1 d.290.1.0 (A:1-130) automated matches {Vibrio cholerae [TaxId: 666]}  ali model 3D-neighbors follow..  14  13..............MDLKQQIVQLVQQHRIHAGSIASCVG---CLSTLHIRLADSVSTLQVSAPFEILSLSGTLTYQHCHLH--AVADAQGRVWGGHLLE. 94
5 -5.840d1gqva1 d.5.1.1 (A:1-134) Eosinophil-derived neurotoxin (EDN) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  46........TTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNIS---NCRYAQ-VACDN-VVPVH....................... 129
6 -5.810d2fcoa_ c.52.1.28 (A:) automated matches {Geobacillus kaustophilus [TaxId: 235909]}  ali model 3D-neighbors follow..  18  2...........MTLEDDLNATNEYYRERGIAVIHKKPTPVQIVRVKRSAAVITEAYFRQASTTDYNGVYRGKYIDFEAKETKNKTAFPL--KNFHAHQIRH 92
7 -5.640d1jr1a4 d.37.1.1 (A:113-232) Type II inosine monophosphate dehydrogenase CBS domains {Chinese hamster (Cricetulus griseus) [TaxId: 10029]}  ali model 3D-neighbors follow..  11  3.............ITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDRFLEEIMTKREDLVVAPAGITLKEAN.... 86
8 -5.470d1gvpa_ b.40.4.7 (A:) Gene V protein {Enterobacteria phage M13, including coliphage f1 [TaxId: 10870]}  ali model 3D-neighbors follow..  17  31..........................QLCYVDLGNEYPVLVKITLDEGQPAYAPGLYTVHLSSFFGSLMIDRLLVPAK....................... 87
9 -5.280d3nceb1 b.1.2.1 (B:1-100) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  1.............MLPPGKPEIFKCRSPNKPGTDGGLPTNYSLTYHREGETLMHECPDYITGG...................................... 58
10 -5.270d2hx0a2 d.290.1.3 (A:5-141) automated matches {Salmonella enterica [TaxId: 28901]}  ali model 3D-neighbors follow..  17  18..............QEVFSQLHAFVQQNQLRAAWIAGCTG---SLTDVALRYAGQEATTSLTGTFEVISLNGTLELTGEHLH--AVSDPYGVMLGGHMMP. 99

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.