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Query: PF06637.9; F1MHE4_BOVIN/1-440; PV-1 protein (PLVAP), from PfamA30U

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGLAMEHGSPYSRAGSSSRGCWYYLRYFFLFVSLIQFLIILGLVLFMVYGNVHVSTESNLQATERRADGLYGQVVGLTASQANLTKELNLTARAKEAINQMMLSARRDLDRINASFRQCQADRVIYMNNQRYMAAIILSEKQCQEHLKEANKSCDALALTLTQKAKTLEVELAKEKLVCTKDKDGLTVGKRVAEEQLAECGKTRDQQQQERQLAEDRLRKVQAFCIPLDRNKFETDLRNLWRDSIIPRTLSTLSFNLYHPLGSELPSIQRACDSLPSIMTSKVEELARSLRAGIDSVTLENEKLQRQKLEVEQSLRASQEAKEKVEKEAQAQAVKLQAECARQTQLALEEKVALQKERDRLVKELEEKKRETEHLKLQLAVSNSALDTCIKAKSQLTIPGPRPAVPVPNPPPIDPASLEEFKRRILDSQRAPASNVLVSALast
1 -88.200PF06637.9; F1MHE4_BOVIN/1-440; PV-1 protein (PLVAP)  ali  100  1MGLAMEHGSPYSRAGSSSRGCWYYLRYFFLFVSLIQFLIILGLVLFMVYGNVHVSTESNLQATERRADGLYGQVVGLTASQANLTKELNLTARAKEAINQMMLSARRDLDRINASFRQCQADRVIYMNNQRYMAAIILSEKQCQEHLKEANKSCDALALTLTQKAKTLEVELAKEKLVCTKDKDGLTVGKRVAEEQLAECGKTRDQQQQERQLAEDRLRKVQAFCIPLDRNKFETDLRNLWRDSIIPRTLSTLSFNLYHPLGSELPSIQRACDSLPSIMTSKVEELARSLRAGIDSVTLENEKLQRQKLEVEQSLRASQEAKEKVEKEAQAQAVKLQAECARQTQLALEEKVALQKERDRLVKELEEKKRETEHLKLQLAVSNSALDTCIKAKSQLTIPGPRPAVPVPNPPPIDPASLEEFKRRILDSQRAPASNVLVSA 440
2 -23.500PF15921.3; G5BJQ7_HETGA/1-1111; Coiled-coil domain-containing protein 158  ali follow..  563..................................................KVIEILRQQIENMMQLVGQHGRTAGAILVEKAQLEKEINDRRLELQEFKVLKDKKDAKIRELEAKVSDLELEKVKLVNAGSERLRAVRDIKQERDQLLNEVKNSRSELNNLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGADGHAVKVAVGMQKQITAKRGQALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELE-VLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHHSRKTTALKEDPTKDLKQLLQE................................................ 911
3 -23.500PF15964.3; SDCG8_HUMAN/6-706; Centrosomal colon cancer autoantigen protein family  ali follow..  11  305..................................................KERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQ-ELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLP.... 701
4 -23.400PF05483.10; SYCP1_RAT/28-813; Synaptonemal complex protein 1 (SCP-1)  ali follow..  11  429..................................................KLAEELQGKEQELTFLLQTREKEIHDLEVQVTVTKTSEEHYLKQVEEMKTELEKEKLKNIELTANSDMLLLENKKLVQEASDMVLELKKHQEDIINCKKQEERMLKQIETLEEKEMNLRDELESVRKEFIQQGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKSKEELHQENKALKKKSSAENKQLNAYEIKVNKLELELASTKQKFEEMINNYQKEIEISEEKLLGEVEKAKATVDEAVKLQKEIDLRCQHKIAEMVALMEKHKHQYDKIVEERDSELGLYKNREQEQSSAKVALETELSNIRNELVSLKKQLEVEKEEKEKLKMEQENTAILTDK...................................... 785
5 -22.700PF01576.17; G3Q6K2_GASAC/841-1921; Myosin tail  ali follow..  11  57.....................................................AEAEEMRSRLATKKQELEEILHDLESRLEEEEERATQMQTERKKMQQNITDLEQQLDQEEGARQKLQMEKVTTDAKLKKLEEDVMVLDDQNNKLLKEKKQMEERISEFTTNLTEEEESLQKLKNKHEAMITDLEDRLRKEEKVRQELEKNRRKLEGDSSELHDQMSDLQAQIDELRAQKKEEELLAALSRIEEEAAAKNAAQKQIRELEAQISELQEDLELERQKHRRDLGEELEALKTELEDTLDSTAAQQELRSKREVEVTHLKKSLEEEAKIHEQQMADMRQKHNQAFEELNDQLEQAKKNKMSMEKAKQALESEWNELQIEMKTLTQGKGDSEQRRKKAESQVQELQVKYSESERQRQEVAEKITKMQSELEHVNSLLSEADN 454
6 -21.700PF14915.4; G1KGA5_ANOCA/157-457; CCDC144C protein coiled-coil region  ali follow..  12  2............................................................QILQDELSVLRLELDRIRIQHQEQESKYL---EENEALKEKIEELKLNEDALTQTVFQCNGQINISKTEAAMLTTKLEHIKEHKERLEMEINSFHSRLNSTAQELERCQLGKNDAERVLQRERDEWIRLKDKLNHDICTLREASNTMSQQLSKSESKANGLENELHQVTYTLREKSLL-------------ESCQRDLNQAQGQVKELENARQAEKDQM-NKYIVKHDSMQERLAQLQSENLLLRQQLEDFQNKSIIKEKVVTDVQDRFNDIFSKLRSDTEKQVQLMEERNKELVTKCDNQREQVLKYEAEKADRE................................................................ 301
7 -21.500PF07888.9; CACO1_DANRE/5-593; Calcium binding and coiled-coil domain (CALCOCO1) like  ali follow..  11  175..................................................RDRGSWEHTRKELERKIDDLKEEVREYREKVEDMKKKQKEVEDLGEALTEEKRALLAQKEANEQRIRELEEDIKILTQRGLERETDLERMRERAKKSAAQKREDEDEHKNLKLKMEQTEKELHSLSQSLRSSLAQRDTHALQLRDTITTLTHKLNSAHRKEAANELALNELRSVQERLNVS--EHCVETLRGELRDMVAQRDSAHAELHQARLQAAQLTLQLADASLALRENWAQERETLQQNAEIDKVRLERQNDEIQQKEEMLQKARMEREKAVVELGREKDCNR-ELKASLRVAQKEKEQLQTEIQEVMEYSRQLERRLEVLSDCKWSETALLQSSRAESPLLSDSEDENPEALQDTHSSGPLNHYSLCEQPQSDLLLPATPPPSPR 567
8 -21.200PF10174.7; H2T771_TAKRU/113-856; RIM-binding protein of the cytomatrix active zone  ali follow..  11  325..................................................TEVDALRVRLEEKEQFLTKKTKQLQDLTDEKSTLTGEIRDLKDMLDVKERKVNVLQKKIENLLEQLKDKDKQLAGLRERVQGFQTDSSNTDTALATLEEALSEKERVIENLREQKEREDRTRLEELDQMRKENQELKDKLTALQPPKELKEFSLVDLMCSSQAVFTLLTSTPIKDLDVWSRLLEQEVARNREDSRKSKAEVERLMLALREAEMEKLSKEKKIADLESIAYGSLLEQLEELMGALEKTRQELDTTKLHLSSTQQSLHERDRHLNSLHQDRRKQLQEILEMKQQALLAAISEKDANIALLELSSSKRKKAQEEVMALKREKDRLMHQLKQQTQSRMKL............................................ 744
9 -20.500PF07058.9; I1Q190_ORYGL/30-591; Microtubule-associated protein 70  ali follow..  1................................................................DEFIALMHGSDPVRVELTRLENELRDKERELGEAQTEIRALRLSERAREKAVEELTDELEKMFEKLKLTESLLDSKNLEVKKINDEKKAAMAAQFAAEATLRRVHAA-DDDMPPIEAILAPLEAELKLARQEIAKLQDDNRALDRLTKQKEAALLDAERTVEIAMADDLQNKNQELMKQIEICHEENKILDKLQRQKVAEVKKLSLTVKELEEAVLRATANVVRDYQRQVQEVNDQKKTLECELARAKVTANRVAVVVANEWKDSNDKVMPVK-QWLEERRFLQGEMQQLRDKLAVAERTARSEAQLKEKYQLRLKVLEDGLRGPPSGSSRLP........................................... 340
10 -20.500PF05622.10; H2QW41_PANTR/12-710; HOOK protein  ali follow..  12  231..................................................RRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTDEAQSLKDEIDVLRHSSDKVSKSYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQ.................................................... 588
11 -20.400PF15070.4; W5MC41_LEPOC/402-1036; Putative golgin subfamily A member 2-like protein 5  ali follow..  15  1..................................................QLMESVQQLKTERDQYAAQLQEEGKVWKDRTEQLLSQVNSLSEEKERSMTQIQELENLVIELRNASALLSQEREDQAAPEP-------------TGPSENETALQEALGKLQQEKDDLSTQYQ----AQVRDNEQLSRLCQEQEERLLELERTVQRFSEDAVDRQQILESMQSDKATISR--ALAQNRELKEQLAELQNGFVKLTNENMELMSALQSEQHVKKELAKKM-GQMQEELHQSREELEGKTQEARSLLEQRDQYLAHLQQYTAGYQQLVAEREELHKQYL-HQVQLMDRLQHEEVQGKVQLELSQKELERAKEKLTQLAKDNESLKTEVKE.................................................... 317
12 -20.100PF12128.6; Q8EAA0_SHEON/8-1195; Protein of unknown function (DUF3584 topsan)  ali follow..  472..................................................ERIHRADEEQESCNAKVERLTSDERKLRAKRDQANEALRIASLRVNERQTALDELHHMLFPQSHTLLEFAIDVPEYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRDDLRRLFDEKRSEQDKINKALAEAQQRLTQLDGELKQLKHQHQLWLEEQKEQALEARMEKQAYWQEVIGALDNQLGQIKATIDARRESAKAEQKACETWYKNELKS-EDNILKLKQQIRELETKISRAEQRRSEVLRFDDWYQHTWLIRKPKLQTQLSDVKRAASEIDQQLKAKTQEVKTRRQQLETERKASDAAQIEASENLTKLRAVMRKLA........................................... 870
13 -20.000PF10481.7; G7NUK3_MACFA/1-307; Cenp-F N-terminal domain  ali follow..  11..................................................GLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCSTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQT-----------------------LPQTTMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQKTPIRRDFCASYFSGEQEVTPSRSTLQIGKRDANSSFFDNS-SSPHLLEQLKVQNQELRSKINELELRLQGQEKE..................................................................... 307
14 -19.900PF05557.11; G3PW04_GASAC/52-714; Mitotic checkpoint protein  ali follow..  11  90..................................................RKVEERDTRLNTANQTISSLKDEIRELKQKIQNQDSAVSSHTLENQELQEHLDLQRRKYQEVSQLCQSLQAAQSSCSEHIITIKERLREDNAFLRESRENCSLLKEEVEGLRKKLERTERNMELEKERVAEKLRAWERKPEDLSREVIHIQQIEISLKEQNYTLNSRVRSAERSQAELRAEKQRGRTQEEQKKREAQDALVRRLQKRVLLLTKERDGMRAILESYDGELAPQLSKRLREAEEVLQRTQKHNVEMEGQLTKAQEEAGTLKLQLHAVELEMESLRKQQASAGDGSSSETKEEVSILRQKIEDLEAERQSLEQQNNVLEMRLERHNLQGDYDPVKTRVLHLKMNPTATAKQQRQQDGEALREEVTRLREVVRSDESGLSLPPP 535
15 -19.900PF09728.7; W4Z3B2_STRPU/161-468; Myosin-like coiled-coil protein  ali follow..  1...........................................................................HMSRAIMQALNGLETPEDKIAALCKKYAELLGEHKSLQRDSKTQTKQLSQIQRERDHLQSEHGRALLAKSKLESLCRELQRHNKTIKEESLQRAREEDEKRKEVS---NKFQQTINEITTQMQDNHTRNIKLKEENIELASKLKNLVEQYERREEHIEKLF-----------KHKDLESQLYDAKLQQSNLALAEEKERNKRE-KELLIAESVDSKRRLEMFTKQEAQLKAQLAVYTEKFEEFQSTLTKSNEVFQTFKQEMD-KMTKKIKKLEKETNLWRGRWETSNKSLMTMVEEKGRHEKDMSDKLIKINRLEKLCRALQAE......................................... 308
16 -19.700PF05701.9; W5B560_WHEAT/161-725; Weak chloroplast movement under blue light  ali follow..  166..................................................KRAEEVLAAGKDIEKRVEGLTVELIAAKGSLELAHAAHHDAEERRIGAVLAKEQDCLAWDRELVQAQEEVQQLNNKLLSQNDLKKNLEANLRKLHGLKSELADYVESILCKEALGVAKEHESEDARQSIKETLASTQKELEEVKANIENTKTEAKLLRVAATTLRSELDREKASLDSLQQRMASIAVSSLEAELNRTQKEIESVRSKEEDAQEKMVELPKMLQQAAQEAE-DAKDAAQAAEEELRKAKEDTEQTKAAATTTSSRLCAVLKEIEASKASERLALAAVRADVEDSPRGVTLPISEYYALSKKAQDAEELANEKVTEALAQVESVKGSELESLDRLTEATKEMDEKKRTLELALERAERANEGKLAAEQQLRKWRSDHEQ... 564
17 -19.500PF07111.10; CCHCR_MOUSE/27-758; Alpha helical coiled-coil rod protein (HCR)  ali follow..  387..................................................EARRRQEQQIASAEEQLKFVVGAMNSTQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRVESSPPSEAAPPLDTDLSVELEQLREERNRLDAELQLSAHLIQQEVGRAREQGEVERRRLIEVAQQLEQELQRAQESLASVGQQLEAARRGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHKATQEKERNQELRRLQDEARKEEGQRLTRRVQELERDKNLMLQRLLAVLPSGV-NKKCSPRSVESSSSESPAAASCKESVKGSLTVLLDNLQGLSEAISRDEDICVEDNQNTK........................................... 732
18 -18.900PF05911.9; U5GNM3_POPTR/17-877; Filament-like plant protein, long coiled-coil  ali follow..  11  2........................................................ENLVKQHAKVAEEAVSGWEKAEAEALALKNHLETVTLSKLTAEDRASHLDGALKECMRQIRNLKEEHE----------------QKVQDVVLNKKKQLDKIKMDFEAKIGNLDQELLR----SAAENAALSRSLQERSNMLIKISEERSQAEADIELLKSNIESCEREINSLKYEVTSKELEIRNEEKNMIMRSAEAANKQHTEGVKKIAKLEAECQRLRGLVRKKLPAALAQMKLEVESLGRDYGDSRLRRSPVKPPSPHLSSVPEFSLDNVQKFNKENE-FLTERLFAVEEETKMLKEALAKRNSELQASRNLCAKTASKLQSLEAQFQI.................................................... 316
19 -18.900PF09730.7; H3DKP7_TETNG/4-712; Microtubule-associated protein Bicaudal-D  ali follow..  10  374..................................................TLKAEYQACQSRYEDDRARLENDVTTLGEKLASLEKTSHVDREEKNKLETELRKLRDVAGESQGSLSVAQDELVTFSEELATLYNHVCMCNNETPDFYKEGKGGRSSPEGRGRRSPILLTKGLFPEPGKTDLSDRAPSPVSSLPSPVSDHRREPMNIYNLVAIIRDQIKHLQLAVDRTTE--LSRQRVASLELGTVADKDKEACMEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKGLKEDAATFSSLRAMFATRCD-EYVMQLEEMQRQLTAAEDEKKTLNSLLRMAIQQKLALTQRLEDLE......................................................... 708
20 -18.900PF09311.9; F6RFI5_XENTR/524-830; Rabaptin-like protein  ali follow..  12  2..................................................DMCSNYEKQLQGIQTQEAEIRDQVKKLQSMLRQVNDQLEKTLKDKKDLEDYMKQNTEETSTQISTLTIRTNQSETLADLQQAFTQAKRNIQDQMAVLMHSREQVSEELLRLQRDNESLQGKHSLHVSLQQAENFSLPETSEELQNLVLKYREDIISVRTAADHLEEKLKA-----------------------------EILFLKEQIQAEQCQKENIEETLQIEIENCK-EEIASTSSLKLELDRVKAEREQLEASLQEKTRALQNLQTLKDSLEDQLKKETGGKA-SLEQLVFEEKNKAQRLQTELDVSEQVQRDFVKLSQTLQVQLERIRQT....................................................... 306
21 -18.500PF06785.9; Y616_CHLTR/25-425; Uncharacterised protein family (UPF0242 topsan)  ali follow..  65..................................................QLRAAAGQLLEAKIRKLTEQDEGLKNIRETIEKRQKETDRLKLHNDKLVEQLGQAREVFIQAKGRYDHMEELSRRLKEENQQLQIQLEAAVRERNEKILENQELLQELKETLAYQQELHDEYQATFVEQHSMLDKRQAYIGNLEAKVQDLMCELRNLLQLEMGAKTNLPGKPVASRDVVAQ-------------------LVLEFRKIVFRVETTEAADSLTALRYTRTDPSAHNYSLACRQLFDGLREENLGMLFIYAPFAQRVLFANALFNDWTGYLEDFLNRESDVVLEGFAQWERDLLTESRVERSGKIVIKTKAFGATPFYYCVVTLDKGP...................................................... 382
22 -18.500PF15905.3; HMMR_MOUSE/15-339; Hyaluronan mediated motility receptor N-terminal  ali follow..  11  13..................................................KTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTTLLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLNAAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDQKNMRALSLELMKLRNKRETKMRSMMVKQEGMELKLQATQKDLTESKGKIVQLE------------GKLVSIEKEKIDEKCETEKLLEYIQEI-----SCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENITFSKQIEDLTVK-CQLLETERDNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQK.............................................................. 324
23 -18.300PF04849.11; H3AF28_LATCH/123-428; HAP1 N-terminal conserved region  ali follow..  11  1........................................................KEGVP--HYTLRADTIFGYDHDDWLHTPLLPPEANLELTPEQIEETLKYFLLCSERVGRVTKTYHDIEAVSHLLEEKERDLELAARIGQSLLKQNQSLTEKDEYLEEQLQLAKEEIAQLRHEIAMRDDLLHVYTNTAEESSTVSTPLRRNESSASLQHYIHLDFLQEKLRGLEEENQKLR-------------------SEATDMVTETVDFEEQEQQLMIDCVQELAEEVGMLSEELARKTEDILRQQEEISQLLAQIVDLQQKCKSITTESEELSQHLA-LSRERQEQLRLELKDLQEKHAEYKELLQETREENKNLRNK.............................................................. 306
24 -18.100PF15254.4; G1T8F1_RABIT/39-892; Coiled-coil domain-containing protein 14  ali follow..  427...................................................ELFSLQSLNMSLQSQLQESLKNQELLQSKNEELLKVIENQKDENKKYTSIFKEKDQTIQQFDIEITKIKIELEEALVDVKSSKFKLDTAEKENQILGITLRQRDAEVARLRELTRTLQNSMAKLLSDLSVDSARCKSGNNLTKSLLNIYDRQQHDPAPAHTSIMSYLNKLETNHSVAHLEPLSTIKNE--ETTEPDRPYENVLPSKGPQPRNTSGREEEPASGIISALSKQDSDAENETLTVIEDECNLDSTVYIPFVRSTSKMNSPLSKRLSPQPQMSVAITQLVSETEKKLCAHAVTCSSRQEVEDAHEKLSRTADTEDKQLLKKIKEAIGKIPVAREDPEA............................................. 779
25 -17.400PF15358.4; G1M5D4_AILME/26-577; Testis-specific serine kinase substrate  ali follow..  10  94.....................................................PPWASDDPDITEILSGVNSGLVRAKDSITSLKEKTTRVNQHVQTLQSECSVLSENLERRRQEAEELEGYCSQLKENCRKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQRQLQ--DETPRRQEAELQELEQKLDAGLSRHGLGPTAQSPGCCGPPGSPNEPPRPRSMAPGGWGMGPR---------------------------------------------AGEGPIVSEQEMQKVSAGLEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRLDGFLGQWE-RAQREQAQAARGLQELRGRADELCTMVERSAVSVASLRSDLEGLGPVKPILEELGRQFQ........................................... 389
26 -17.200PF05667.9; CCD22_AEDAE/1-553; Protein of unknown function (DUF812 topsan)  ali follow..  11  246..................................................LQYYSKGGTKHRLAEPSGAAASSGTTEKVVLNNITVETKPGKTPLESLQEEIDALQQEIVQHSEEGVQLESSRKETDESIEEYRKTIVRLKEEKKIKERTHILLE----DPEVNVKKLEAIIAAGGERMKKLQDQWDAHRIPLVDTLEAYRLKNSDKLSKSQQVLDQIESTRQKCEEVVID--------------------------LQTKGAMYARLQKEFEKLNKTVSRTAYSRILEIIGNIRKQKNGIDQILQDTRSLQKEINNITGQLDRQFTVTDDLIFR-NAKKDEHSKRAYKLLVTLHSDCEELIKLVQEIKREVRDLEDQIENEKGR....................................................... 553
27 -17.000PF17078.3; SHE3_CANTT/23-265; SWI5-dependent HO expression protein 3  ali follow..  11  1.......................................................STKVIDSLHSKIDELTDELTTLKQSHQELTKKHSIVAKKNDSFVDQLANAKHENDMLSALLKRKERRILDLEDQYNDLNSQIENLSLSNKNMKIRCENLQNNSNASIAEFERLKISYDALIASQMEYKNHYQQELNTLQTSFDKYRTENTKRYEDLQSSISSNDK------------------------------------DIDTLLDSLTNKRKTMDNIYVNKNNKILQLLTSLASLIKLHAEDTKGQVEQNVDVIKILMEKYPDLQEKILEKEKVE........................................................................................................... 242
28 -17.000PF09789.7; Q16UI1_AEDAE/24-343; Uncharacterized coiled-coil protein (DUF2353 topsan)  ali follow..  10  1........................................................HRKLQSKVEALKIMRNELEKYRSERDQFKLMAETLQMRYSAMKSSLNSPEFQAAGFG-HSSAVSLLVNQTRERNISLSTEVEALRQRVHELEGDIDVLRTKNFDLQAAFNKMKSTEETKLR--DRKGIVWDEEKSKLIAQMETLKKKNAQLQYDVRSLLDEKEDVVMERDAYKCK--------------------------AHRLNHELSVMLKGDQSQQKIVDDGLILENKYQQEKITNLENELELSRQSATKYKNMLDTKRKKGIIKLGTNNQVKDLLERGTVEELPLKAATISELKSLCLALLDNVNDKSLALSHQKKTNKLLAAKITELEQRILAL............................................ 320
29 -17.000PF01540.14; O53101_MYCHO/1-353; Adhesin lipoprotein  ali follow..  10  76..................................................TKSFKEAGSYGDYPAIISKLSAAVENAKNEKKAIDDKNAQIAKELAERNAKIQSNIEELKKINNEAFELSKTVNKTIAEVEKKFKIEASFKE---QLENFADDLLDKSRQIDEFTTVTSTQEGFTLAELESFKEITTTWFNGMKSEWARVLDAWKNELTEINSIIKGVE--------------------------------------------ELKKLSHEISEFSNSVKKTISELEKKFKIDDKTNKDEAKQFKNELENFADQLLNKSHEIDKFVTVTSAREDFSLSELESFKSFNTTWFNEMKCEWARVQEAWKDQLKEIST.................................................................. 352
30 -16.700PF04111.10; W1QBV0_OGAPD/127-441; Autophagy protein Apg6  ali follow..  4....................................................TDCASTLIDELKQQFEQMTKEKDTYVQFLKKLTAQSGPNRKKAQDSLSELALLKEEETKLLEELEKAEKEEEQLTQQLVEVEQELEDLENQEKEFCLQKNAYDLELIEFVNERERIKASYEYNLNRLDSLRKTNDVFMISHDDQFGTINGLRLGNLDNVKVSWHEINAALGQLALL.................................................................................................................................................................................................................... 182
31 -16.400PF15742.3; F1SF94_PIG/172-554; Domain of unknown function (DUF4686 topsan)  ali follow..  12  13..................................................EELQQLRQDLHRLQVLCSSAEKELRYERGKNLDLKQHNSLLQGESLKIKTELKQAQQKLLDSAKMCSSLTAEWKHCQQKIKELELEVLTQAQSGKSLSSLEEALAREKSNVAAAEEKISDLQQKLAETCILGKKQLEERIKEAMENEAKIKQNYQEEQQKRKLLHQNMNELQNQVKTLQDRQLKMTNVQQQLRIQQQEAQLKELKNERRLCDEHLKSNQELSEKL-SGLQQEKEALGRECGRLLKQLDVHVRNYNEKHQHHKAKLRRVRDHNTNESIETLEEEKEFQKQVIAQNDTLSLEKRKLREQLVRQEGIIDKNRWMLSSVQKRVLFLDQENKHFLENNLQL............................................ 383
32 -16.200PF03528.13; RABE1_RAT/9-495; Rabaptin  ali follow..  11  1..................................................QPDVSLQQRVAELEKINAEFLRAQQQLEQEFNQKRAKFKELYLAK---EEDLKRQNAVLQAAQDDLGHLRTQLWEAQAEMENIKAIATVSENTQEAIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRLEQERAQWAQYRESADREIADLRRRLSEGQEEENLENEMKKAQEDAEKLRSVVMPME-------------------KEIAALKDKLTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQEDAEKLRKELHEVCHLLEQERQQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQLRQVEELKKKDQEEDEQQRINKGKDN............................................. 327
33 -16.200PF06008.12; LAMA1_HUMAN/1575-1831; Laminin Domain I  ali follow..  11.....................................................PVPYGILSNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIDFTQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASH------------------------------------VLSKHNNELKAAEALVREAEAKMQ-ESNHLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDAL........................................................................................................ 257
34 -16.100PF03148.12; G3VSY1_SARHA/16-397; Tektin family  ali follow..  35.................................................NQTIWDEHDNQTRLSERIDSVERWKETLDRCLADLDTEIDALTQMKEVAERALQAKNLPMDVAIECLTLRESRRD--DSVEDELHKEVEVIDCAKEALQQKIREIFEQLCLLQEARQQLNFDHRDKMEALEIDRACLSLNVHSPNLSLKVNPTRIPNGSCTIQQWDDFSQYNKEQAEAERKASADLREATALTIAETNNELEAQRVATEFAFRKRMREIEK--------ALNGLKWQEKSTLGETVDFEEDIRQVEEDLSIKMRNMKLAHTRLDIRTYRMELSRDQVQYGLTNEVHQLEANIATLKQKLTQAQDTRGSFYKHLARIQADIACKTNSLM..................................................... 369
35 -15.900PF10212.7; PPR21_MOUSE/255-771; Predicted coiled-coil domain-containing protein  ali follow..  14  111..................................................EEECESSLCTPALRARNLELSQDMKTMTAVFEKLQTYVTLLALPSTEPDGLLRTNYTSVTNVGAALHGFHDVMKDISKHYSQKASIEHEIPTATQKLVTTNDCILSSAVTLTNGAGKIASFFGNNVDSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADRLRGTTSAQLPGLAQENATVPIASSQEESLVGMLTRTPDSEAPDVESREDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQNLQDELMTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMASK............................................................ 517
36 -15.900PF00261.18; I3J233_ORENI/12-247; Tropomyosin  ali follow..  10  1.........................................................RKIQCLQQQADDAEDRAQVLQRELDSERELREKAEGEVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEE----VARKLVILEGELERAEERAELSECKASDLEEELKNVTNNLKSLEAQSEKYSEKEDKYEEE------------------------------------------KVLTDKLKEAETRAEFAERTVAKLEKSIDDLEEKLSHAKEENLGMHQVLDQTLQELN....................................................................................................... 235
37 -15.600PF09787.7; W4YU02_STRPU/423-727; Golgin subfamily A member 5  ali follow..  10  2.........................................................................AEEAKQELTDYKQKATRILQSKDKLISSLKEGVEGIEGSTAVSYELEEIKNERDMLREELQQANIKIEQLKMDLQEIESLQQMESESLQEQLRDLEDQEIQSRQSLRETEADLARKCEELRYAEEELHRQRLDLQAKIKDREDDIQRLRNQLKTKSMSSSSET---------------------------------------------ELEGRLHALTESLIQKQTMLETLSSEKNSLGLQLERLQRQYKEVQATATPTHTVNIEEEEASTRQRLPLFMQEAPSDGGMTRKVKQAASTIDKFSIRLGVFLRR....................................................... 271
38 -15.500PF15066.4; G3SWC7_LOXAF/1-522; Cancer-associated gene protein 1 family  ali follow..  11  233..................................................EETAVSPSEIQNSGEMPEMSVSHQREARVEDVESPGLFSAWSPTDVSWSGGGFRGECKTSDTERSFENLQPL-----EEDMALNEVLRKLKHTNKKQQIRIQDLQCSNMYLEKKVKELQVKITRQQ-VLVDIINKLKENVEKLIEDKYKVILEKNDGDRTLKNVQEILSDTQKHLQESRNEKKTLQAE-------------------LKKIKVNYIHLQERYMTEIQQ-KNKCVSQCIEMGKTLSKKEKEVERLQQVKGELEKATASALDLLKRERETRVPEFLSLQEEFQKHEKRNLQERQKLKSSLEELVTQVK.......................................................................... 522
39 -15.300PF10168.7; I3KZS6_ORENI/8-718; Nuclear pore component  ali follow..  12  458..............................................................................................................................................................................................STYECILLPLLSSIRPPSPPLLCSHPGLGSASSPLRGLAEDSFEQHIRNILARSSTNPLVLKAGDKDTSPPPPELELLSRATQVFREEYILKQDMAREEMQRRVKLLTGQKNKQLEELSLCREERKSLREAAERLADKYEDRQETIMNRVKKVLCSLQSQLPILSNSEKEMKKELQTINDQLKHLDNCIRQVNMKMEYQKTQVDKDMPGTRARVSLNAPQKKVVQDVLKEQGQQIGDMMKQIKDIKNHFS 711
40 -15.300PF06818.13; H3A1M8_LATCH/446-647; Fez1  ali follow..  12  10..................................................GEISLLKQQLKDSQVELAQKGNEILSLKAQLRGVRAELQACEDQLQELQEAAHTKTLELEVCENELQRKKNEADLLREKVGKLEREVAGLREMVARSRQSQEQEDAFLLYESDEAKAQRDTLLGLRQQVERLKAELLYERRRSEDQLEGFEEERRTWHEEKEKVIRYQKQLQHNYIQMYRQNRELERE.......................................................................................................................................................................................................... 200
41 -15.100PF04108.10; S8BG25_DACHA/15-418; Autophagy protein Apg17  ali follow..  28..................................................NALIDASIMASRASFLQNGIKDELKLLQHANTLMENQRETARKGFQTSLGDLDEANHRLDEILSLLRATEVEEAFSTAEKSEQQVQRDGIENLRSRLRGIIDQVQETDENFESHLEPFTQLIAFITESLGALSKKSAPAIPNPVVAITPSLQSMEDHASVMASLLESLARHYDLCSMALKRAESHDSGVSSQEGDLQTE--EDKADMLAVLQRDAGEVDDVVTEIKERL-DEMETTSVLVEQTVAHIGDHYRTMLSLLSKMHESLVNCTIQSKEFVQKQMDNQGVIAERLD-ELQRLTDHYVLFGEAYDALLVEVGRRIAVQRQKDSIIQEALAKIDMLNEGDLN............................................. 379
42 -15.000PF10498.7; IFT57_XENTR/25-383; Intra-flagellar transport protein 57  ali follow..  10  115..................................................HIHFSWKRPTYPTEEQDEENVIEDDAELTLNKIEDEIAEEDSDNDQEHFIDLNALSAQTQKLNTKESSKPEEILESNTDAAEWILEVERLPQLKVTIRTDNKDWRVHVDQMHQHRDGIDTSLKETKGYLDKLHNEVAKALEKVSSREKYINNQLEQLVQEYRSVQAQLSEAKERYQQASGGVTERT-------------------RILAEITEELEKVKQEMEEKGSSMTD--GAPLVKIKQALTKLKHEIVQMDIRTGVVEHTL............................................................................................................................. 359
43 -14.900PF15450.4; G1PIP2_MYOLU/56-586; Coiled-coil domain-containing protein 154  ali follow..  13..................................................KRWKQLEQWVADLQAEVVSLRGHKDYCERATLSLLQELRQVQASVQLQDSELKKLKQELQQAAWVPEKEALEFPQNQNKMQALDKRLVEVREALTQIRKQQALQDSERKGTKQEANLRLTKLARKLEQEEQNREVQEEASQKVDQEVARLQAQVTKLGEECGFLQKSFLALEKRMKTSESTRLKVESSLREELESRWRNLQELAEERLQALRGQCKVGSSGWAQEESYLLEGLDRAVVQLTKFVRQNQVSLNRVLLAEQKAQDTKGHLEESQGELAAYLQENMEAMQLASEQARQETQSTLELLQEKRQALEGSVAELVTQVGDLNDHFLALSWRLDL.................................................... 376
44 -14.900PF15771.3; F7CHR8_HORSE/9-582; Domain of unknown function (DUF4700 topsan)  ali follow..  77....................................................GDKKDGGLFPLPLSVGKSKGLLEQFEEKKKRAKDR-----CDSEALYNFISHTRESIYRLQTSVEKSEEHL-----------------SSRSQSILDSLETVAKTLQETAQAQSDLVLETAQDKGNMEQAILEMQKRFEARQAEFSEMKSNLKHLEVLVAQQNKDFQQLCEQLGQLNVPSILAELKRLISVPQVPRHVKDSTSQTSPPLAQSLNFTRQDKYASEEPILWQAQALPAARILNRGSLQPGEFGVWGKNDTLQKEAALLAVGTGKRNRPVKDKAVQTNCKNLAITKTGSENHSLDIQGHKVPGDRDLVSPGASQLISLDLNNFATSIKN.................................................... 393
45 -14.700PF08614.9; K5XJL3_AGABU/10-204; Autophagy protein 16 (ATG16)  ali follow..  10  6..................................................IERDATESSFSSVIEQYRRLAQQTKLLKERNATLLRAVGSVKSGQGSSAVSAPASSEENPIRAAYLASLESQISSLRDELATVYKTQGQNAQRLLAMNETLREKEELARLDTENLRKTKDELRRKVDQHAELMQEKDRTVQILHDEISTLQLELGQIEDRNQTLLKDNAKLLQRWLDAKQAEAN.............................................................................................................................................................................................................. 192
46 -14.500PF14662.4; H9GPA1_ANOCA/135-325; Coiled-coil region of CCDC155 or KASH  ali follow..  1..................................................EEAADLMNSIKDLQQGNKQLAVQNTKLQRTIETAEELNSRLSEEISELKGKLRSTQQQARAVANELEDLKVFSKTLEEENNRLHAQTRQLEKEQQLLFVRVDNLQEENKKLLTEKENSKKELFTKKASLKSKICEYEKLTSCKDAALNEKTKRIEELTMILDEYRTVVEELRLEVRRLQDHLCQS............................................................................................................................................................................................................. 191
47 -14.500PF15619.4; C3YX78_BRAFL/18-210; Ciliary protein causing Leber congenital amaurosis disease  ali follow..  12  14.....................................................KDLTSQIFELQRELDDLRRENKLLKTLQHKQEKALTRFEDQESDLPQLLARHSAEVRNLKERLRHKQDSNHRSEQKIKDLRDDLEKKEHQVSKLQKIVRDKNAERDELNRKLMRTEQMLLDKEKKVTELNKHLELVQGSSTRQLNAERARHKETQDKLSSLQEEYERLQNKLKEKEKE................................................................................................................................................................................................................. 192
48 -14.300PF09738.7; LRRF2_XENTR/31-329; LRRFIP family  ali follow..  10  14.....................................................EARDIRMRELERQQKELDEKIDKQFTENYSRPSSRNATSGIPGTFTPLSGSSSRRGSGDANSSLDPDASLSELRESLAEVEEKYKKAMVSNAQLDNEKSNLVYQVDTLKDVVEEMEEQMAEYHRENEEKSKEL----ERQKHNCSILQHKLDELKEGIQQRDEFIEKHGLVIIPDGTPDINHEPVVGAITVVSQEAAHVLESAGEGPLDVRLRKLAEEKEELVAQIR-KLKLQLDDERQRSAKNNSTTTDSTGLENGSDLQLIEMQRDANRQISEYKFKISKAEQDMT................................................................................................... 298
49 -14.300PF09755.7; T1IG88_RHOPR/5-307; Uncharacterized conserved protein H4 (DUF2046 topsan)  ali follow..  15  1...................................................ASESDSSSIDGGPIMMPPSPITREQLQKRIESLQQQNRVLKVELDTYKLRVKALQEENRGLRQASVIIQAKAEQEEEFIS----------------NTLLKKIQALKKEKETLAHHYEQEEECLTNDLSRKLTQLRQEKCKLEQTLEQ-ECLVNKLMRKIEKLEAETLAKQSNLEQLRREKVELENTLEQEQEALVNRLWKRMDKLETEKRTLQIKLDQPVSDPASPRDLSNGDTASNLSAHIQHLRGEVSRLRAQLAHAQQEHTEKMEKFAKEEKHVKEENLRLQ----RKLQLEVERREALCRHLSESESSLEMEEER..................................................................... 301
50 -14.200PF14817.4; M0SMJ6_MUSAM/11-762; HAUS augmin-like complex subunit 5  ali follow..  11  28....................C------VWSF--LLQRVRSERTV--MMVHGVAAGEAGRGRRREEEKGRAAFKDGSSAEAREVAVRERELAEEEADRLRNVVRRQRKELKARMVEVAREESERKRMLDERSNARHKQVILEAYDQQCDEAAKIFAEYQRRIHQYVDQARDIRRLITGSANDVVDDLHAPGEKAVYSAIKGLRSSDDSVLIEMSREKNTRKACETLAAHMTEKIRTTFPAFEGSGISMNSQIDAAKLSLDLDGEIPEDIKVIIRDALKNPPLLLQSITTYALRSSALIHRETEEIRAVAESLRYKYENYGNGKTGTELSSNGNYDQLLERQKAHVQQFVATEDALNKLSHKLLIRLPGSSDVGAHFELEVLAREREVAGLRASLSTLTSEVQRLNKLCAE--KEAEVSLKKKWKKIEGFDTRRSELET... 489
51 -14.200PF03904.11; YP2A_STAAU/1-230; Domain of unknown function (DUF334 topsan)  ali follow..  8..................................................MSMKDIKNNKENPNTQMNSKSTGTPSSSTQNSLNNEELSELKRQNKLIVKYLAEIQENQKIREKEQKEITSELKEATKDFRDKSLKIRNDFVDVLQEKLKHVDTEELKDILGRGIYKVREENDRMLQEVKRSHEHYQTRQKYLFTGIGAM................................................................................................................................................................................................................................................ 157
52 -14.200PF08317.9; B6HCL6_PENRW/924-1250; Spc7 kinetochore protein  ali follow..  11  78.....................................................RELKSYISEGRQVIRSIEAE---TYAENPALFKEYVTAPPDIRVIMDNQFRNVKTHARLLSKATWYEWRMKLLEGLKEGLLRHVEEMKADDDLLSEREELLNRNVPLLVEKHASLEQEATNLQQLVDEMENCDQDELRSTRSKLSEVDSEIAAKRRELEQLQEEVKEKVTFIEAGAEMRDEFL-AQIQEAERVKEECRGWSAREINELKASVQRIQQ.......................................................................................................................................................................... 290
53 -14.200PF13779.4; D7A9C0_STAND/55-942; Domain of unknown function (DUF4175 topsan)  ali follow..  10  450..................................................RALIDERRVLAFDANQRERVEAGLDALAIAPEKFTPDPSHYMGANAKSDEDLRGVVAYLWEIAVRIEDGDSDVEKKLRDAQQALQNALENNASDDEIKRLTQELREAMQEFMQALAEEAQRNAQADSDQPMGPNTRMVRPQDLQKMLDRIEDARDAARQMLSELQNMLNGLQAGRQQQRRQGQNQMSQAMDQLGDMIRRQQQLRDRTFKQGREQGQQGEQGQQGQQDQRFGDLKQSQEQLREQLRQLREKMQQAMRGRQQGQGE-QGQQGQGEQQGQNGQGQQGQQGEGQQGQGMPGEGGLGEAEQAMREAEQALGQQSEALQALRKGAQQMAEAMQQQPGQGQG-YGDDVTVKVPDEIDMQRARRVLEELRRRFGEPERPRLELDYLER 885
54 -14.100PF04582.10; Q9DPB5_9REOV/1-326; Reovirus sigma C capsid protein  ali follow..  2....................................................AGLNPLQRREVVSLILSLTSSTTTNPGDLTAVYERLTNLEASTKSLRQSLSSIVSDLSDVSVDLQDTTRALDDAIATLKGLNTTVAALQNSVASLSSTVNGLTDISSAHSEALSFLRTTIDGNTVAIS----NLKGDVSTNGLNIADLQNRMKSLESSTSHGLSFSPPLSVADGVVSLD................................................................................................................................................................................................................. 176
55 -14.000PF10234.7; CLUA1_MOUSE/14-283; Clusterin-associated protein-1  ali follow..  125..................................................KAARQLASEITAKGASLYDLLGKEVELRELRTEAIARPLEINETEKVMRIAIKDLLAQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLQTLQSVRPAFMDEYEKVEEDLQKQYDVYLEKFRNLAYLEQQLEDHHRMEQER.................................................................................................................................................................................................................................................... 270
56 -13.800PF17097.3; KRE28_ZYGRC/1-362; Spindle pole body component  ali follow..  11  1.......................................................MKSDLDGYEVRIKSLENQTAHYSEQA--LLEQEQRVLASLREITQNVIAMGQENSLVEIKGELESKEESELVIDPSGFQEKIDTFVELVELLKVTHLEQETLDNFLRYTISSSNLLQINSVQD-SQVKELEQGTLESHKREIEATKGQIKNLCQELSMAQDSINETFLDTSNALEEALLNELTQLRMEKQTSEEADTIEDDPVSQTYEDWESLQKSKLEL-----RLLEEETSRLQSRVESYEDYQKRSRQLSNNDPRMLQNHKRKFQFDVEPTFTVVITLADQTTFQNVQVYRKDAKSLVMDHGLNDEIKNSYLGTNNIYNGLNDIIHTLQR.................................................... 362
57 -13.600PF15934.3; B3MK61_DROAN/489-722; Yuri gagarin  ali follow..  1..................................................................................................................................................ILKEIADLICKLRSTDFSYNEIY-NETSTENPFCVAIMEMFDEKSEQTEKEYESLAANERLVCQISALKETLNDRNELINHLQSMIGNYSDM---SENNRLKEENHDLKMKNSENIRKAREIAEQLNGQVTQRVE-LVNKYESLSSSFEEQCQELKGANRRVQSLQTRLCQVEKLQEELRTERKMLREEVI-ALKEKDACSVGRERALQDQLRCSQMDLDKSRCLIRNMQSQLQQQDKL....................................................... 233
58 -13.500PF10186.7; B2WCB9_PYRTR/3-373; Vacuolar sorting 38 and autophagy-related subunit 14  ali follow..  20..............................................................ARAYLEHPRIELAKTLIDLDGVEKHVKAIINGSEDKAIQHVSLTDSKGGLLVDRQECTNNL-----NWQRTKAETAEIQERLGNISDHAHQLRQQMEATRKLLEAKRAANAQRKSDLSSATYGIESRRDKVQQKVKRLDYNADKMHHDTIDLRMQLCTTAAKLAGLKMQRRKTRDGGVKEV..................................................................................................................................................................................................... 199
59 -13.300PF04094.12; Q7XPH2_ORYSJ/208-1047; Protein of unknown function (DUF390 topsan)  ali follow..  11  381..................................................SAEPLLQALAAANTAVLDGFSAQVEALRAERAELEAAWTRVEEGRRSVDAMVEVGRKAHRRHISELEARKAALAEIARE-----------------VEEEREAALIATTAMIEAQDSLRLQHGSWEAELKKKLDAAQGVLDAAAAREQRATEAKAACRQREEALEARAMALEDHAGAVEISDREAAAAIREVTLAAHEAACAEEESALRLREDALAERERALEESEAATQRLTDSLSLRKAAQEEQARRNLECIRAERAALEQRAANLEAREKELDARERS------GGAATGESDLVARLAAAEHTVADMQRALDSSTGEAEALRLLGEIGPGMLWDAVSRLDRAGREAGLWKGHTISHSTNLEGLAPHLRRMAWAVQRLPEELEKT.. 747
60 -13.100PF02463.17; SMC_BACSU/2-1172; RecF/RecN/SMC N terminal domain  ali follow..  12  636.................AKLLGHRYRIVTLEGDVVN-----------MTGGAVKKKNNSLLGRSRELEDVTKRLAEMEEKTALLEQEVKTLKHSIQDMEKKLADLRETGEGLRLKQQDVKGQLYELQVAEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEEDITKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETEL-----ALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIA-LRRDQRIKLQHGLDTYERELKEMKRLYKQKTTLLKDEEVKLGRMEVELDNLLQYLREEYSLSFEGAKEDPEEARKRVKLIKLAIEEL-DEFERVNERYKFLSEQKEDLTEAKNTL............................................ 1017
61 -12.900PF04518.10; O84625_CHLTR/450-835; Effector from type III secretion system  ali follow..  69................................................FFKFRALAQVESTKLDGTLQGSENFLQKINQLRTDLFSYQLLAQSYEIRIDRYMPQEIDYLTQMKSDLYYSNFGSSVGNAMIEAIAQFVNGAT--------NFASFAGQQPMTAMAQDTFPGSKETAETKLALEKQQAKLYLQYATQALKVVQEQMERVQNDKVITNEQRLRITDALKGYADN--------------------NAISGSLVLLQVYLNPLSVGVRDGNQGG-NDTGTDPKGTFHVFGGQDQWQARLEILEDALVSPSNIISGGLFPVQASVQSDQQAYADMGQNYQLEMQMHMTAMQQEWTVVATSLQILNQIYLGLTRK.............................................................. 386
62 -12.900PF05010.12; F6UEE1_XENTR/677-877; Transforming acidic coiled-coil-containing protein (TACC)  ali follow..  13  4.........................................................................................................................................KDMDAAIEAVRLEVQEKELEVLEWKNKHEKLYLEYVEMGKIIAEFEGTITQMLEDSQRQKEMGKLELSKVLQEKQQVQVDLNSMEKSFSEMFKRF------------------------------------------------EKQKEVLEGYRKNEEALKKCVEDYLARIKKEEQRYQALKAHAEEKLNRANEEIAHVRSKAKAEATALQATLRKEQMKTQSLERSLEQKSKENDELTKICDDL.......................................................... 200
63 -12.700PF15290.4; M3ZY07_XIPMA/184-491; Golgi-localised syntaxin-1-binding clamp  ali follow..  10  38................................................................RYKRVSLGRYRSCEDNHGVRPPNPEQYLTPLQQKEVAIRHLKTKLMESENKVHDRENEIQEFKSQLCRMREDWIEEECHRVEAQLSLKEARKEIRQLRQVVETMKNSLMEKDKGIQKYFIDINIQNRKLESLLHSMELAQSGSALQDEGALDFMCDGPEG........................................................................................................................................................................................................................ 197
64 -12.700PF05478.9; F1S5C8_PIG/18-820; Prominin  ali follow..  124........GEMHQRQKKNGNFLRKYFAVSLL--VICLLISIGIIYGFVANQHMRTKAGEVKHFTTMAVNLGTAFIILAKQIDYIAEQYTTTKER---VFSDLDNIKVLLGSR---YQQLKPKLIPMLDDAMAIGEELKTLRESLVQANLNLMDTKQSLTQLGHNLSDVRRGLEQTLSDSTCHADPVQTTCNDIRSSLGLVNVSIN--PDQLPSLEEHINNLTAVLRT--------------------------------NLTALAHQGYNYLYTIPERVQNETVNIIADVKRALNSIGSNIETASQGF-PIRDRLSYFSSYLKKAEDYIHRYLRVLEE...................................................................................................... 411
65 -12.700PF15272.4; E7KJ61_YEASA/173-368; Spindle pole body component BBP1, C-terminal  ali follow..  1.........................................................EYKKAYFDLFAQMDLNSRDLEDLCEDVREQREQFHRNEQTYKQAYEEMRAELVNELKKSKTLFENYYSLGQKYKSLKKVLDQTISHEAELATSRERLYQEEDLKNFEIQTLKQRLSDLELKYTNLQIEKDMQRDNYESEIHDLLLQLSLRNNERKDTSAGSNIFS.......................................................................................................................................................................................................................... 165
66 -12.700PF10473.7; F6RLX8_MACMU/2309-2448; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1  ali follow..  13  3..................................................KKQLCVLEQLKESEHHADLLKSRVENLERELEIAGKNQEHAALEAENSKGEVETLKAKIEGMTQSLRDLELDLATVRSEKENLTNKLQKEQERISELEIINSSFENILREKEQEKVQMKEKSNTAMEMLQTQLKELHE............................................................................................................................................................................................................................................................ 140
67 -12.600PF17060.3; MPS2_ZYGRC/12-339; Monopolar spindle protein 2  ali follow..  99..................................................QEPDVSTTPTRQQRSSPRKVNRLLKNLETRVASMKDELKFKDEILAEKDRELIQLTRKLSDYKDKYEFVQRQFSFYKDHGESPRRNSSESEQ-LNLEQNASTKHEFIISELKRKLQEQTLAISNLKEQLQRGEGAGVLYTNYSKRYNPLHND.............................................................................................................................................................................................................................................. 249
68 -12.400PF09632.8; YPKA_YERPE/436-732; Rac1-binding domain  ali follow..  36.....................................................SDLDTMLVALDKAEREGGVDKDQLKSFNSLILKTYRVIEDYVKGREGDTKNSSTEVSPYHRSNFMLSIVEPSLQRIQKHLDQTHSFSDGSLVRAHKHLETLLEVLVTLSQQGQPVSSETYGFLNRLTEAKITLSQQLNTLQQQQESAKAQLSILINRSGSWADVARQSLQRFDSTRPVVKFGTEQYTAIHRQMMAAHAAITLQEVSEFTDDMRNFTVDSIPLLIQLGRS--------SLMDEHLVEQREKLRELTTIAERLNR............................................................................................................................ 291
69 -12.400PF14992.4; H0VD66_CAVPO/13-287; TMCO5 family  ali follow..  10  1...........................................................................................................................................................................IISLNTDLEKDMQRIDEANQEMLLKIQEKEHEIQRLESEITQMEDSARDEEWEKENFMIVEKERALQELEEKSAKLERKNETLVHSITELQRKLARKP---YKITKYAQCDLDSNSEELQVKLQQLEASCADQEKKLAKIIEDYAFVVQLCEDQALCIKKYQETLRRIEEELETRFLEREVSKVLSMDSLRRNCEDQNNECTSFPKTATWLCKR....................................................... 211
70 -12.300PF15818.3; G3T452_LOXAF/26-1066; Coiled-coil domain-containing protein 73 family  ali follow..  1..........................................................QLLDFKTSLLEALEELRMRREAETQYEEHIGKIIVETQELKWQKETLQNQKETLAKQHEELQMKMCALEEEKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKLSEMEQKVQLAKEDHHKQLNEIEKYYAIITGQFGLVKENHEKLERNVQEAIQLNKRLSALNKKQEFELCSLK-KELKKVTSDLIKSKVTCQYKMGEENTNLTIKERKFQELQERLNME-LELNKKINEEISRIQEEKQNVIISFQHMQQLLQQQTQANAEMKAELKVLKENLERDNELQREKVRENEEKFLNLQNEHEEAQGTWKKHVEELNGEINEIKNELSSLKETHIKLQEHYNKIYDQKKFEEDKKFQNVPEVSNEHSRMSAEKSEDTTILT 394
71 -12.300PF15233.4; I3M9X9_ICTTR/45-196; Synaptonemal complex central element protein 1  ali follow..  10  2.............................................................SLEPQIEVLINRINEVQQAKKKASEELGEARTVWDALQKELDSLHEEKVHLKEILSKKQESLRILRLHCQEKESEAQRKHTLLQECKERIFALNSQIEEEKNKQRQLRLDFEEQLEALMGQHKDLWERPEQLAREICTLDSSKEQLLKE...................................................................................................................................................................................................................................... 152
72 -12.300PF12097.6; Q5NIP1_FRATT/1-374; Protein of unknown function (DUF3573 topsan)  ali follow..  4.........................KINIVFICFLVLSITPFMGFSNSFKNSNEQSQKSNSIDKQGITQLQSQIANIQAEINHLTQIKNSNNSAQFATYSSKVENIGLPNSLPDNNKLTLDIMTNIDSDSSIINLSDCSIGGIFDK...................................................................................................................................................................................................................................................................................................... 124
73 -12.000PF06160.10; R7G8R1_9FIRM/22-573; Septation ring formation regulator, EzrA  ali follow..  10  96......................................................AARRRLNELSDDLALCETDVNKIHTVLDDILEQENEQRVHINALKETFRKVKKTIHENRTAYSQSYEYLETEIIAIEKMFSKFEEWMFASEKAADQQKEIKESITRLNEIVEALPSLYERAKGILPRAIDEVGYNYARAKNK--EVSKNLDVISDMLKNDLNRLHSGTPENVKEDLDDLEVRIAQLAEQIRLEEEAFDEVNDGLTALFDSIREVNCEFDDIKSLYARVYERGFENWTQRLQDTQTRLDVLNDMQRRLDKIVLDKQVPYTTILIAYKELAQSNA-GFSKEVELMKEKLNNACSDEERAKKQLIKLQLIINEIRVKMLKHR......................................................... 431
74 -11.900PF12495.6; Q58XI2_BACTU/12-188; Vegetative insecticide protein 3A N terminal  ali follow..  12..................................................................IYGFATGIKDIMNMIFKTDTGGDLTLDEILKNQQLLNDISGKLDGVNGSLNDLIAQGNLNTELSKEILKIANEQNQVLNDVNNKLDAINTMLRVYLPKLTSMLSDVMKQNYALSLQIEYLSKQLQEISDKLDIINV-NVLINSTLTEITPAYQRIKYVNEKFEE.................................................................................................................................................................................................................. 174
75 -11.800PF10226.7; F6QKS9_MONDO/11-201; CCDC85 family  ali follow..  10  1................................................................KEDLSKVPDEELLRWSKEELARRLRRAEGEKMGLMVEHGNLMKDVNR----------RLQLHLHEIRGLKEVNQKLQDDNHELRELCCFLDDDRQKGKKLSREWQRFGRHTAGVLWKEVALSQQKLRELEARQEALLRENLELKEIVLMLDEERSGAGSR........................................................................................................................................................................................................................ 150

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.