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PF00009
Query: PF00009.22; EFG_CHLPN/9-286; Elongation factor Tu GTP binding domain, from PfamA26U

Results of FFAS03 search in SCOP175
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SAIRNIGIMAHIDAGKTTTTERILFYAGRTHKIGEVHEGGATMDWMAQEQERGITITSAATTVFWLGAKINIIDTPGHVDFTIEVERSLRVLDGAVAVFDAVSGVEPQSETVWRQADKYGVPRIAFVNKMDRMGADYFAAVESMKEKLGANAFPVHCPIGSESQFVGMVDLISQKALYFLDDTLGAKWEEKEISEDLKERCAELRANLLEELATIDESNEAFMMKVLEDPDSITEDEIHQVMRKGVIENKINPVLCGTAFKNKGVQQLLNVIVKWLPSLast
1 -129.000d2bv3a2 c.37.1.8 (A:7-282) Elongation factor G (EF-G), N-terminal (G) domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  58  4KRLRNIGIAAHIDAGKTTTTERILYYTGRIHKIGEVHEGAATMDFMEQERERGITITAAVTTCFWKDHRINIIDAPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGND-LGTDIREIPIPEEYLDQAREYHEKLVEVAADFDE---NIMLKYLEG-EEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPS 276
2 -101.000d2dy1a2 c.37.1.8 (A:8-274) Elongation factor G (EF-G), N-terminal (G) domain {Thermus thermophilus, EF-G-2 [TaxId: 274]}  ali model 3D-neighbors follow..  29  2..IRTVALVGHAGSGKTTLTEALLYKTGAKERRGRVEEGTTTTDYTPEAKLHRTTVRTGVAPLLFRGHRVFLLDAPGYGDFVGEIRGALEAADAALVAVSAEAGVQVGTERAWTVAERLGLPRMVVVTKLDK-GGDYYALLEDLRSTLG-PILPIDLPLYEGGKWVGLIDVFHGKAYRYENG----EEREAEVPPEERERVQRFRQEVLEAIVETDE---GLLEKYLEG-EEVTGEALEKAFHEAVRRGLLYPVALASGEREIGVLPLLELILEALPS 267
3 -36.300d1n0ua2 c.37.1.8 (A:3-343) Elongation factor 2 (eEF-2), N-terminal (G) domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  24  15TNVRNMSVIAHVDHGKSTLTDSLVQRAGIISA--AKAGEARFTDTRKDEQERGITIKSTAISLYSNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIKPVVVINKVDRALLELQVSKEDLYQTFARTVESVNVIVSTDEVLGDVQVYPARGTVAFGSGLHGWAFTIRQFATRYAKKFGVDKAKMMDRL-----------------GDSFFNPKTKKWTNKDTDAE-------GKPLERAFNMFILDPIFRLFTA 285
4 -30.500d1wb1a4 c.37.1.8 (A:1-179) Elongation factor SelB, N-terminal domain {Methanococcus maripaludis [TaxId: 39152]}  ali model 3D-neighbors follow..  27  7....NLGIFGHIDHGKTTLSKVLT-------------ASTSAHDKLPESQKRGITIDIGFSAFKLENYRITLVDAPGHADLIRAVVSAADIIDLALIVVDAKEGPKTQTGEHMLILDHFNIPIIVVITKSDNAGTEEIKRTEMMKSILQSTHNLKNSSIISAKTGFGVDELKNL........................................................................................................ 168
5 -28.000d2c78a3 c.37.1.8 (A:9-212) Elongation factor Tu (EF-Tu), N-terminal (G) domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  31  5....NVGTIGHVDHGKTTLTAALTYVAAAENPNVEVKD-YGDIDKAPEERARGITINTAHVEYETAKRHYSHVDCPGHADYIKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYVVFMNKVDMV................................................................................................................................................. 133
6 -23.600d1g7sa4 c.37.1.8 (A:1-227) Initiation factor IF2/eIF5b, N-terminal (G) domain {Archaeon Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  17  8.....VSVLGHVDHGKTTLLDHIRGSAVASREAGGITQHIGATEIPMDVIEGICGDFLKKFSIRETLPGLFFIDTPGHEAFTTLRKRGGALADLAILIVDINEGFKPQTQEALNILRMYRTPFVVAANKIDRIHGWRVHEGRPFMETFSKQDIQVQQKLDTK-------------------YELVGKLHEEGFESERFDRVTDFASQIIPISAITGEGIPELLTMLMGLAQQYLREQLK....................................... 225
7 -23.000d1zunb3 c.37.1.8 (B:16-237) Sulfate adenylate transferase subunit cysN/C, EF-Tu domain G-like domain {Pseudomonas syringae pv. tomato [TaxId: 323]}  ali model 3D-neighbors follow..  26  11....RFLTCGNVDDGKSTLIGRLLHDSKMIYE-GDDVDLALLVDGLQAEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILVDARYGVQTQTRRHSYIASLLGIKHIVVINKMDLNGESIKADYLKFAEGIAFKPTTMAVPMSA..................................................................................................................... 190
8 -20.400d1kk1a3 c.37.1.8 (A:6-200) Initiation factor eIF2 gamma subunit, N-terminal (G) domain {Archaeon Pyrococcus abyssi [TaxId: 29292]}  ali model 3D-neighbors follow..  21  7....NIGMVGHVDHGKTTLTKALTLRRGITIKIGFAD---AEIRRCPNCGRYSTSPVCPYCGHETEFVRVSFIDAPGHEALMTTMLAGASLMDGAILVIAANEPCRPQTREHLMALQIIGQKNIIAQNKIELVDKEKALENYRQIKEFIEGTVAENAPI....................................................................................................................... 171
9 -20.400d1f60a3 c.37.1.8 (A:2-240) Elongation factor eEF-1alpha, N-terminal (G) domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  28  8....NVVVIGHVDSGKSTTTGHLIYKCGGIDK--GSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEDGQTREHALLAFTLGVRQLIVVNKMDSVKQEIVKETSNFIKKVGYNPKTVPVPISG..................................................................................................................... 192
10 -13.100d1mkya2 c.37.1.8 (A:173-358) Probable GTPase Der, N-terminal and middle domains {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  18  6TDAIKVAIVGRPNVGKSTLFNAI---LNKERAL---------------SPIPGTTRDPVDDEVFIDGRKYVFVDTAGEKYSNYRVVDSIEKADVVVIVLDATQGITRQDQRMAGLMERRGRASVVVFNKWDLVVHRYDEFTKLFREKLYFIDYSPLIFTSADKG-WNIDRMIDAMNLAYASYT............................................................................................... 185
11 -12.300d1mkya1 c.37.1.8 (A:2-172) Probable GTPase Der, N-terminal and middle domains {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  18  3.....VLIVGRPNVGKSTLFNKLV---------KK--------KKAIVEDEEGVTRDPVQDTVEWYGKTFKLVDTCGSQKMKEVTLNMIREADLVLFVVDGKRGITKEDESLADFLRKSTVDTILVANKAENLREFEREVKPELYSLGFGEPIPVSAEHNI..................................................................................................................... 150
12 -10.600d1nrjb_ c.37.1.8 (B:) Signal recognition particle receptor beta-subunit {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  13  1SYQPSIIIAGPQNSGKTSLLTLL----------------------TTDSVRPTVVSQEPLSAADYDGSGVTLVDFPGH--LSDYLKTRAKFVKGLIFMVDSTVDPKKLTTTA-ESSCENGIDILIACNKSELFTA---RPPSKIKDALESEIQKVI---EEDYAENTLDVLQSTDGFKFANLEASVVAFEGSINKRKISQWREWIDEKL..................................................................... 209
13 -9.360d1wf3a1 c.37.1.8 (A:3-180) GTPase Era, N-terminal domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  18  8.....VAIVGKPNVGKSTLLNNLL-----GVKVAPISPRPQTT----RKRLRGILTEG--------RRQIVFVDTPG---MDQEVYEALADVNAVVWVVDLRHPPTPEDELVARALKPLKVPILLVGNKLDAAKYPAMKAYHELLPEAEPRMLSALDERQVAELKADLLALMPEGPFFYPE................................................................................................. 178

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ye Y, Li Z, and Godzik A. Modeling and Analyzing Three-Dimensional Structures of Human Disease Proteins Pacific Symposium on Biocomputing 11:439-450(2006) [PDF]