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PF13514
Query: PF13514.1; B5J9R5_9RHOB/33-1144; AAA domain, from PfamA26U

Results of FFAS03 search in PfamA26U
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst IYGPNEAGKTTTMEAALRLFYGFPLREAYAFKHQRNNLQVSATFDIEGAARRFTRLPKRIGSLVDETGTALPEAALSAHLAGLSEGDYRQLLCLDDETIERGGEEIANAQGDIGRLLFSAAAGVADLSGVLDGVRDEANSIWKKRGRTTRIAELKHALADVEKEIREKDVTAGAWKGLKKALTQAQEYEQAARKSRDVLNISKAQIAGQQRALPLMAEISTLEKSTATYSEYPDQLDFDPERLIELRTDHGTASQNIERLTMEITALKNELDEITLDKEQLELAVQLDALHDLSVRNRSAQLDLQRRQVEKDVAEEAMSSAALDLGVSPKADLQDLVLSQADISKLETAKEELRDAIASVANESREVADLKKKLEAAGDAVETNTGDTDDSPSISDVLVRFDVDRLAPAHAAALQAIGAAKTKARKALSALTFGTVVFEDVPTGVSSMIQAQSWAAEHEKISQTIHNTIDKRDNHQEDLATRIAQGKVLTAGGAVVTDAETEVLLTAREDLWAEHQAALESQTASAFYEAMQKHDKAMDARVTHASELGQLRQIEQAEVEAQIRLEQADKRLEVLDKELTALDAAVGAAARQAGLTSTITSAEWLDWVARNSTATEDAQALFAAREEHQPILDRAEDLRAELSRLLTFEATDVASALTVARQVAEGERKQSENEARAQETLQQAKRNLRKREERHQAALSVEAEARNAWYTLILEMLGDRIAPENLQASLEPLRELREHAKTRASAAQRVASMKVDQERFAEEVAALAKAYNLETLETAAETFSALKTLSDRARSAHEAVEKLTGDIKEAEARKSKNSEKLREIKQAIEAIASGFPYSTSLTEIDELRTVVKRAQQVIEERAALVKLQRTVVSELGVNDIKAAREEMAALSLTDLEAAFENSKSDLERAEEELTQAIEIRVAAEQGVAQVTGDADIATLVEQKATLELQLEDSALEHLELSLGHYLASNSIRRYRDSHRSGMMTATERCFASLTQGAYPSLITQVDKDAEVLLAVDCTGASKRAAEMSKGTRFQLYLALRAAAHEQLVAQGTRLPFFCDDIFETFDEDRTSAACRVMETIGSRGQAIYLTHHRHVVDIAMKVCDTPPVIHEILast
1 -209.000PF13514.1; B5J9R5_9RHOB/33-1144; AAA domain  ali  100  1IYGPNEAGKTTTMEAALRLFYGFPLREAYAFKHQRNNLQVSATFDIEGAARRFTRLPKRIGSLVDETGTALPEAALSAHLAGLSEGDYRQLLCLDDETIERGGEEIANAQGDIGRLLFSAAAGVADLSGVLDGVRDEANSIWKKRGRTTRIAELKHALADVEKEIREKDVTAGAWKGLKKALTQAQEYEQAARKSRDVLNISKAQIAGQQRALPLMAEISTLEKSTATYSEYPDQLDFDPERLIELRTDHGTASQNIERLTMEITALKNELDEITLDKEQLELAVQLDALHDLSVRNRSAQLDLQRRQVEKDVAEEAMSSAALDLGVSPKADLQDLVLSQADISKLETAKEELRDAIASVANESREVADLKKKLEAAGDAVETNTGDTDDSPSISDVLVRFDVDRLAPAHAAALQAIGAAKTKARKALSALTFGTVVFEDVPTGVSSMIQAQSWAAEHEKISQTIHNTIDKRDNHQEDLATRIAQGKVLTAGGAVVTDAETEVLLTAREDLWAEHQAALESQTASAFYEAMQKHDKAMDARVTHASELGQLRQIEQAEVEAQIRLEQADKRLEVLDKELTALDAAVGAAARQAGLTSTITSAEWLDWVARNSTATEDAQALFAAREEHQPILDRAEDLRAELSRLLTFEATDVASALTVARQVAEGERKQSENEARAQETLQQAKRNLRKREERHQAALSVEAEARNAWYTLILEMLGDRIAPENLQASLEPLRELREHAKTRASAAQRVASMKVDQERFAEEVAALAKAYNLETLETAAETFSALKTLSDRARSAHEAVEKLTGDIKEAEARKSKNSEKLREIKQAIEAIASGFPYSTSLTEIDELRTVVKRAQQVIEERAALVKLQRTVVSELGVNDIKAAREEMAALSLTDLEAAFENSKSDLERAEEELTQAIEIRVAAEQGVAQVTGDADIATLVEQKATLELQLEDSALEHLELSLGHYLASNSIRRYRDSHRSGMMTATERCFASLTQGAYPSLITQVDKDAEVLLAVDCTGASKRAAEMSKGTRFQLYLALRAAAHEQLVAQGTRLPFFCDDIFETFDEDRTSAACRVMETIGSRGQAIYLTHHRHVVDIAMKVCDTPPVIHEI 1112
2 -47.000PF02463.14; SMC_BACSU/2-1172; RecF/RecN/SMC N terminal domain  ali follow..  11  28VVGPNGSGKSNITDAIRDIIFGSDSRKRLNLAE-------DHFLPIDFHEVSVTRR-RSGESEFLINNQPCRLKDIIDLFSGLGKEAFS----ISQGKV----EEILSSKAEDRRSIFEEAAGVLKYKTRKKKAENKLFET---QDNLNRVEDILHELEGQVEPLKIQASIAKDYLEKKKELEHVE-DIEELHGKWSTLKEKVQMAKEEELAESSAIS-AKIEDTRDKIQALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKET-EELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIEQLKSDYFELLNSQASIRNELQLLDDQMSQSAVTLQRLADNNEKHLQERHDISARKAACETEFARIE----QEIHSQVGAYRDMQTKYEQKKRQYEKNESALYQAYQYVQQARSKKDMLETMQGDFSGFYQGVKEVLKAKERLGGIRGAVLELISTEQKYETAIEIALGASAQHVVTDDEQSARKAIQYLKQNITEDLKGANELAKLLKKKNNSLLGRSRELEDVTKRLAEMEEKTALLEQEVKTLKHSIQDMEKKLAD-------------------------LRETGEGLRLKQQDVKGQLYELQVAEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEEDIDRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAA--------KHKLNDKTKTIELIALRRDQRIKLQHGLDTYERELKEMKRLYKQKTTLLKDE----------------------EVKLGRMEVELDNLLQYLREEYSLSFEGAKEKYQLETDPEEARKRVKLIKLAIEELGT-----------------NLGSIDEFERVNERYKFLSEQKEDLTEAKNTLFQVIEEMDEEMTKRFNDTFVQIRSHFDQVFRSLFGGGRAELRLTDPNDGVEIIAQPPGKKLQNLNLLSGGERALTAIALLFSILKV-----RPVPFVLDEVEAALDEANVFRFAQYLKKYSSDTQFIVITHRKGTMEEADVLYG........ 1161
3 -43.000PF12128.3; Q8EAA0_SHEON/1-1188; Protein of unknown function (DUF3584 topsan)  ali follow..  21ICGTNASGKTTLQRLV--VFYG-TRDSFERWYLPHDSSYI----------YEYQKADGLLYQAVAGDGKGVNYRFIAK----LNTREYRAIIQNDRTLLSTGSNALCDGEEKLAKAVHSKEGKMETVKSMIAAILEEDGVNPPSSRLNPQRVEAWIRESQLIQGFEVIRPEFEKLEQEFNQLLSAEMRLSSLSRGYRNDESLEADRLEIQQ-----TLSKELNLKLRMLDD------EWKEVRDELNLDLSAAKGDVAKCEYELDAIEDQHGAFL-DANIEQAKADLDMLPNWRADMENLSERHKLQTEKHQDIEAAYNARRSKIGEQLNRELEGLHSEQDKQRE-KQREVARGDLDALEAQWRSQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLN--LAIFDERIHRADEEQESCNAKVERLTSDERKLRAKRDQANE--ALRIASLRVNERQTALDELHHMLFPQSHTLEFLRKEAQGWEQSLGKVIAPELLHRTDLHPSVTGESDTVFGVNLDLKAIDVPEYAASEQELRIRLSKAEEALQSAQELQAEAESQLVAINGELDKLSRELTFARTAYKNSRDDLRRLFDEKRSEQDKINKALAERKAFQQRLTQLDGELKQLKHQHQLWLEEQKEQALEARMEKQAYWQEVIGALDNQATIDARRESAKAEQKACETWYKNELKSRGVDEDNILKLKQQIRELETKISRAEQRRSEVLRFDDWYQH-PKLQTQLSDVKRAASEIDQQLKAKTQEVKTRRQQLETERKASDAAQIEASENLTKLRAVMRKNNEEAQGSLGERLRQGEDLLLKRDYLMGSVKQYVEHFDSVIASKSGSGLAETWERAREESSFINDKGIRLLDYRKLV--PQLEQLLNVIVPQSIMALREQGRIFGVDLTAFYDVLADIDRRIASQSARITREVGEDGVSESAVRIRSKISELEFWPELEQFVKAFKNWKADGFNGLPDEEYTNSMRRALDIIGR------AALTGGISKLLEIELRLKEGNSDLIIRQLSHGMAYLILCKFLLAFTRLLRGRAD-IHWPIDE-LGTLHHTNVKKIFDAC----GNNNISVLGAFP................... 1170
4 -34.100PF01576.14; O44934_LOLPE/1067-1925; Myosin tail  ali follow..  12  7................................................................................................RDLEDAGRKKDMEINGLNSKLEDEQNLVAQLQKKIKELQARIEEL------EEELEAERQARTKVEKQRTELS---RELEELGERLDEAGGATAAQMELNKKREQELLRLRRDLEE-QHESQIATLRKKNQETNELGDQIDQLQKVKSRLEKEKTQLRAEMDDVQSQVEHAGKNRGCS--EKMSKQMEAQLSELNAKIDDQARSVSELTSQKSRLQTEAADLTRQLEEAEHNVGQLTKLKSSLGASLEDAKRSLEDEGRLRAKLQAEVRNLNSDIDGIRESLEEEAESKSDLQRALSRANAEVQQWRSKFESEGAARADELEDAKRKLQAKLSEAEQTADTLHSKCAGLEK--AKSRLQGELEDLAIDVERSSAHANNLEKKQRNFDKVVSEWQHKCNDLQAELENAQKEARSFRVRAQCEEVGDTVASLRRENKNLADEIHDLTDQLGEGGRNTHELEKARKHLALEKEELQAALEEAEGALEQEEAKVMRATLEISQIRQEIDRRLQEKEEEFD---NTRRNHQRAIESMQASLEAEAKGKAEALRIKKKLEGDINELEIALDATNRGKAELEKNVKKYQGQIRELQSQVEEEQAQRDEAKEHYQMAERRCAAINGELEELRTILEQAERARKAAEELADASDRVNELQAQVSTVGSQKRKLEGDVTAMQSD---------------LDELNNELKDADERAKHAMADATRLADELRQEQDHGLSVEKMRKSLESQVKELQVRLDESEAAALKGGKKMIQKLESRVRELEAELDSEQRRHAETQKSMRKVDRRVKELSFQQEEDRKNYERMQELVDKLQNKIKTYKRQVEEAEEI--AAINLAKFRKVQQELEDAEERADQSEGALQKLRAKNRS........................................................................................................................................... 859
5 -33.100PF15921; G3SYM2.1/1-1109; Coiled-coil domain-containing protein 158  ali follow..  3............................................................................................................................QKVCETHNEDLFSSSGI------TSNEGSSPFFMSSIRGTIIENT---SSTGNLTQIPFFPKYEVELDSHRKTISYPGKEHIERVLE--EYSHQVKDLQRKLSESELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLR------QLQNTVHELEAAKCLKDDMLKDSCTQIEQLRKMMLSHEGVLQEIRSVLVDFEEASGKKVYDHESMLHVRNLGSAIGKILRELDTEISYLKGRIFPLEEQLEALKSESQNKIELLLQQHQDRIEQLMNEHEVEVTGLTEKASSARSQANSIQSQLEIIQE-----QARNQNSMYMRQLSDLESTVSQLRSELREAKRTYEDKIEELEKQLVL-----NSELTEARTERDQI-SQESGNLDDQLQKLLGDLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS--QEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNMQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQEKAQLEKEINDRRLELQEFKILKDKKEAKIRELEARVS-DLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTCRSELNSLTEDYEVLKRNFRNKSEEMETTTNKLK----MQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNASKEKHFLKEEKNKLSQELNTVAT--EKNKMAGELDVLRSQERRLKEKVANMEVALDKFAECQDIIQRQEQE.................................................................................................................................... 828
6 -30.900PF13166.1; Q63PW4_BURPS/9-780; AAA domain  ali follow..  10  39....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TTLSRIIRSLETGSISPRYASPSFSITISGAVITNNNIPAQGHDIRVYNKDFVDEHLAFLRDEQGHISPFAVLGSKNKEIEVEIDKLEDELGSVENKTGLRHSYQEKKKAHADKKKAAQDAQDELDKKIFDKANKNPTGIKDANYDVRKLKLDIKTVQDKKIAPLDDADRSSKVKLLSEVALPDIEKRLSFNSSLPALAKSTVELITKKIKPSAPIQELLNDAILQNWVKSGIPLHEATR---PADLWKRLGDHFNQESQDLEKDLDSVLTKISNEKTRIKNVVTVDRKNFYSANQATFDNLKADLDDAINNHEKSLQSLEDELNARKKDIFTERSTIDVQDNTVSISQKVSLVNELIERNNKTTTSLEEDQKIARNELSQFTIDIDLAGEEKKIKALEDQITKAKDELDAVEAEGKKRVDRVKELRTQLRDRGAEQVNQYLGHFLGHGGLSLSAVEEANTATYRFQILRGDQ-AAYNLSEGECSLVAFCYFLAKLEDIETKGKKLIIYIDDPISSLDSNHIFFVFSLIENYYRYEQLFISTHNLEFLKYLKRLTKP....... 635
7 -29.200PF10174.4; Q7Q0K7_ANOGA/59-838; RIM-binding protein of the cytomatrix active zone  ali follow..  10  1..............................................................................................................................LKAKLENAQGEQESL------KQEMERGQAGIQRIVSERDKAY---AELEKIREELERTQATLGKSQLTQEKLQNSLDKAQ------------NEIDHLQEKLDKSGGETRRLQLEKEKINYEFENIQSQLDKSLGQASRIQKEKEAAQ------------MDLDRYRDKADKLQSSLARLQKERDVLSDELEKLKEKSESTQSTALKYQRERDAIQTELEVVKERWEKAHQVHQKLQMERDDATTEIDILKEKLDKALYASQKLIDEKD-----TSTKEFEKMLEKYDRAQNEIYRLQSRVDTAEADRNRLE---------VEAERSALAAAKAREDLRKIQEETTRLQEACDRAAMQLGRSKE----------------LEDKAKEDVDMIRERLDKCQTDLRRAQSEKDNQQAEIERLTYELDRSHNLYTKQTASLDSAQEEIARYGLEIEKMRERYEKTAAEL------------RRLQENESFSREARRMKDENDRLREKYDKVIVELENFRGKSQYEQETFDKMKEKFETRENEFQTMELKLHETSLQLDLARAEVTKLISNQDKQRADAERAHIEYEKIRDKHEKLIKEVERLRQNPQSAIALAATSTVSLADKNELDRLRDRLEKALQSRDATEME---------------AGRLAKELEKAQLHLTKQQEVYEATRIEFERMSAELTRVLERLEKSEA---------EKETLRQSTKIYEKHHQQHASNHHIEQSLMKLEADNKQLMAERDQLVMQLEKSQDMLMSFQQELNAAEVELQRQCEENRRLKSSPQQPGSTKLKQMLQETGARGDNELEQWRKVVEQEKNRADQAEKAAIELQKRMQ..................................................................................................................................... 779
8 -26.900PF05483.7; SYCP1_RAT/28-813; Synaptonemal complex protein 1 (SCP-1)  ali follow..  10  60............................................................................................................................HYQEGVNDSDFENSEPM------SRLYSKLYKEAEKIKKWKVSIE---SELKQKENKLQENRKIIEAQRKAIQELQFENEKVS------------LKLEEEIQENKDLIKENNATRHWCNLLKETCARSAEKTSKYEYEREETRQVYVDLN------------NNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYQKEVNNKE------NQVSLLLIQSTEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLK------------ELNEKKDHLTSELEDIKMSMQRSMSTQKTLE----------------EDLQIATKTIYQLTEEKEAQMEELNKAKTTHSLVVTELKATTCTLEELLRTEQQRLENNEDQL---------KLITMELQKKSSELEEMTKFKNNKEVELEELKTILAEDQKLLDEKKQVEKLAEELQGKEQELTFLLQTREK-----------EIHDLEVQVTVTKTSEEHYLKQVEEMKTELEKEKLKNIELTANSDMLLLENKKLVQEASDMVLELKKHQEDIINCKKQEERMLKQIETLEEKEMNLRDELESVRKEFIQQGDEVKCKLDKSEENARSIE--YEVLKKEKQMKILENKCNNLKKQIENKSKNIEELHQENK-ALKKKSSAENKQLNAYEIKVNKLELELASTKQKFEEMINNYQKEIEIKKISEEKLLGEVEKAKATVDEAVKLQKEIDLRCQHKIAEMVALMEKHKHQYDKIVEERD----------SELGLYKNREQEQSSAKVALETELSNIRNELVSLKKQLEVEKEE--KEKLKMEQENTAILTDK................................................................................................................................................................ 785
9 -26.900PF05911.6; Q10P54_ORYSJ/79-939; Plant protein of unknown function (DUF869 topsan)  ali follow..  11  1..................................................................................................................................................KDALVKQHAKVAEEAVSGWEKAE---AEASALKLQLETVTLAKLAAEERAAHLDGALKECMKQVRTVKEEGEQKLHDVVFAKTKQWEKIKAEFEAKLLEFEQELIRAGAENDALSRSLEERGDLLMKI--DEEKARAEAEIEVLKNTIQSGEREINSLKYEIHVVSKELEIRNEEKNMSVRSADVATKQHMEDVKKISKLEAECQRLRGLVRKKLPGPAALAQMKMEVESLGRDYGESRLRRSPAKNSSFHRPMSPMSPVPDYAFENLQHMQKENEFLTARLLSMEDETKMLKEALAKRNS--ELQTSRNMYAKTAGKLRGLEVQMLTGSQRKSTSNPNMDIHFDGALSQNGSNPPSMTSMSEDGVDDEGSCTESWANALVSELSHIKKEKGAKSSVTEGEMEKLACLSSEANGHVSTVEKMKIDDTEASLSGITERDGVKDSQSVLALPGTPSNKLQLS-LLKLQSRISSLLDSESPQNNAGNILDSIRNILKDIEDEADSSNDSKTHHGDMVEVADNGSLMKHSSSGSKHAMDQELVNAILKIQDFVKSLDQEVSKFQGQSSDCDGLCDKIQQFSALVEKALSNENVLNDIVMTLSLILSGTSEIKVQLEPLKDSISGPCLPRSSSDPEIEGPTDSGCDVKTAVQICSSEEFEQLKSEKLNLEAELSKCNEVIEETKFRFKELEKSLE---------------ELTSKLVASEKSNSLAETQLKCMAESYKSLESRKAELENEIKVLQSKIEVLTAELDDERQNHQEDITRYRDLEEKIERYENEKEIAAAAEKLAECQETILILGRQLQSMRPPAESMGSS.............................................................................................................................................. 861
10 -23.900PF09730.4; Q3TBD4_MOUSE/9-723; Microtubule-associated protein Bicaudal-D  ali follow..  2........................................................................................................................................................................QAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQ---------TELKQLRNVLTNTQ----------SENERLTSVAQELKEINQNVEIQRGRLRDDIKEYKFREA--RLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNNLRKELSHYMSINDSFYTSHLQVSLDGLKFSDDTVTAEPNNDAEALVNGFEHSGLVKSSLDNKTSTPRKDGLAPPSPSLVSDLLSELSEIQKLKQQLVQMEREKVGLLATLQDTQKQLEQARGTLSEQHEKVNRLTEN--------------SALRRLQAGKERQTSLDNEKDRDSHEDGDYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKISLLEKASHQDRELLAHLEKELKKVSDVAGETQGSLNVAQDELVTFSEELANLYHHVCMCNNETRVMLDYYREGQGKAGRTSPEGRGRRSPVLLPKGLLATEVGRADGGTGD---------------NSPSPSSSLPSPLSDPRREPMNIYNLIAIIRDQIKHLQAAV-----DRTNELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLE..................................................................................................................................................................................... 714
11 -23.000PF07111.7; CCHCR_PANPA/27-782; Alpha helical coiled-coil rod protein (HCR)  ali follow..  14  62................................................................................................................................................SQQAEVIARQLQELRRLEEEVRLLRETSLQLEAQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLR--KQLSKTQEDLEAQVTLVENLRKYVGEQVPSEVHSQTWELE--------------RQKLLETMQHLQEDRDSLQATVELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLK----------------GQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQ-------------------------------------LELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEEAAAQLPSLNNRLSYAVRKVHTIRGLIARK-LALAQLRQESCPLPPPVADVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQ---LSKVAQQLERELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQ--------EKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSVVSSPRPPECSASAPIAAAVPTRES---------------KGSLSVLLDDLQGLSEAISKEEAVCQGDNLDRCSSSNPQMS....................................................................................................................................................................................... 755
12 -22.700PF05557.8; Q9W6G9_XENLA/2-716; Mitotic checkpoint protein  ali follow..  10  2..................................................................................................................................................DSEDNTTVISTLRSFNKFLSQPL---EGTAPSLGTSTSTGASLQMQFQQRFLLEDQAAQIRSKSNLIQVEREKMQMELSHKRARELEKAASTNAKNYEREADRNQGLHTRIKALEEKENEFQNKLQEQ--NEMIKSYKKTIEAQSKKLLEKEDKLSESNENISVLKGKASELQWKIMNQEMQIKTQETEKQELTEQLEIHRKKLQESNEKMQALHELQAQNADNEQKIKSLEQKLSAQEQDAAIVKSMKSDLTKPKLERELQQLRDENAYHREMKENNALLKEEVEGLRRAAERFNKMKEDLVGSEIEKEQLVKKLKLWENLEQSTGLNIRTPDDFSRQIMAV-----------------------QQRELKLKEENMTIQISARMLETSRQQLQEELLKVQSGFLEEKKRREHQEALVRRLQKRVLLLTKERDGMRAILDS-------------------YDSELTPTEHSPQLSRRLKEAEDILQKVQDHNAEMETQLSEALEDAGIQKQKSELLTAELKVLKSQMGSSDQNISFTNEAMSALRLKIEELEAERGRLEEENKILEMRLESLNLQGCYDPSRTKVIHSLNPASKAKQQRTDTVRHLQEECDKLREIVRILEGGAQ-----------IPDKLEATGSPQSSQELAELKKQVESAELKNQRLREVFQTKIHEFRTACYML..................................................................................................................................................................................................................................................................................... 635
13 -21.900PF05622.7; HOOK3_HUMAN/5-718; HOOK protein  ali follow..  11  113...............................................................................................................RMLQLILGCAVNCEQKQEYIQAIMMMEESV------QHVVMTAIQELMSKESPVSAGN---DAYVDLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQ--EEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDY--RIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSK------EGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVV------------ELQNRLSEESKKADKLDFEYKRLKEKVDSLQ----------------KEKDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKL-----------EEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKKYLEKAKSVIRTLDPKQNQAAPEIQALKNQLQERDRLFHSLEKEYEKTKSQREMEEKYIVSAWYNMGMTLHKKAAEDRLASTGSGQSFLARQRQATSSRRSYPGHVQPATAR....................................................................................................................................................................................................................................................................................................................................................... 714
14 -21.700PF15964; Q5PQY1.1/1-716; Centrosomal colon cancer autoantigen protein family  ali follow..  11  1.....................................................................................................................................................................................MAKSPGNSTLEDSLGQYQRSLRERANR---------SIHQLKCALREVDATIEEDALDPSTSINVENVDTGVAWHELQHSHAVNQLKALLRQQTSTENETSPRRRKLSPSRPSDCEDGSLPTMHNLVPIINDQSQYIHHLEAE---------------------VKFCKDELSSMKNRVQVVVLENERLQQELKSQRQEETLREQTLLD--------MSGNVQNSWMKTREDSRVIETTKRPFSHGDAETGKAASTGDADKWRLELERLKLTYEAKTDLLESQLKLLRKDLVEYQKTCEDLKERLKHKESLVTASASSRVGGLCLKCAQHEAVLSQTHNNVHIQTIETLTKERDDLMSVLVSVRSSLAEAQSAYKQVKHAVQMTEEANFEKTKALIQCEQLRSELERQTDRLEKELASQQEKRALEKEMIKK--EVTREREEAEAKMLILSQNIAKLEAEIEKITREKTSAVSQLEEVQNQLASQEMDVTKVCGEMRFQLNKTKMEKDEAEKEHKEYKAKSQKDLEMKDQEIEKLR----------------LELSESTQQVEQEQQKAARARQECLQVTELLGESERQLHLTRLEKDSIQQSFSNEAKAQALQALQREQELTQKIQQMETQHDKTDSEQYLLLTSQNTFLTKL------------------KEECCILAKKLEKVSLKSRSEIVQLS----------QEKRYLCDKLEKLQKRNDELEDQCVQHGRVHETMKERLRQLDKH--GQATAQQLVQLLNKQNQLLLERQNLSEEVDQLRAQLPSMPQS....................................................................................................................................... 714
15 -19.200PF15070; Q5DTL1.1/404-1022; Putative golgin subfamily A member 2-like protein 5  ali follow..  10  1........................................................................................................................................................QLMESLKQLQVERDQYAENLKG-AMWQQRVQQMAEQVHTLKEEKEHRERQVQELET---------SLAALRSQMEEPPPPEPP-AGPSEAEEQLQGEVEQLHKELERLTGQLRAQVQDNESL--SHLNREQEGRLLELEREAQRWSEQAEERKQILESMQSDRTTISRALSQNRELKEQLAELQNGFVRLTNENMEITSALQSEQHVKKELARKLGELQERLGELKETVELKSQEAQ------------GLQEQRDQCLSHLQQYAAAYQQHLAAYEQLTSEKEAIH---------KQLLLQTQLMDQLQHEEVQGKMAAELARQELQEAQERLKATSQENQQLQAQ---------------------SLLVLPGEGDVDQEEEDEEVPQSSLAIPEDLDSREAMVAFFNAAIARAEEEQARLRVQLKEQKARCRSLSHLAAPVQSKLEKEAVVPRNVDDSASEESQALHVAMEKLQSRFLEVMQEKVELKERVEELEHCCIQLSGETDTIGEYIALYQNQRAVLKARHLEKEEYISRLAQDKEEMKVKLLELQELVLRLVNERNEWQ-------------GKFLAVSQNPGDVLTPVPTGSQEFGAADQQDDLREVSLA----DDIEPAQGEAGVPAPHENPTAQQIMQLLREIQNPRERPGLGSNPCIPFFYRADE.......................................................................................................................................................................................................................................................................................... 610
16 -16.900PF13175.1; A9A6W0_METM6/4-391; AAA ATPase domain  ali follow..  12  227...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KTYKDSKIPNIIPFANLETDEFIKDLQKVNLDINLIKSTDRQRKKNHHGAININLQEDYSKYWTQSESNLEITWDNNNVEFWVKE-DNTSYTPEQRSKGKQWHLAFYIRITARS---KEGKNNILLIDEPGLFLHAQAQEDIINKLEDASKTMSIIYTTHSPYLL................ 388
17 -16.200PF04094.9; Q8S5S8_ORYSJ/246-1073; Protein of unknown function (DUF390 topsan)  ali follow..  11  371.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PLLQALAATNTTVLDGLSAQMEVLQAERAELDAAWARVEEGRRSVEAMVEAGRKAHRRHTSELEARRRDLAEIAREVEEERETALIATTVLNEARDDLRLQYGSRAAELEKKLDAARGVLDAAAARERRAAENEAASRQREEALEARATALEERARAKERDMADRE----------------AAVAIREATLAAHEAACAEEESALRLREDTLTERGRALEEAEAAAQRLADSLFLREAAREEQARRNLEGARAKRAALDQRVAELEARAKELDARAHSGGAAVGDGDLAARLAAAEHSIAELQGADSSAGEVEALRLAGEVGPGMLRDAVSRLDRAGRQAGLWGGRCAKYAANQGGLAQRLSEMAGTLQRLPEELEETIKSSSRDLARGAVELVLASYQARDPDFSPWAALEEFPPGTEDGARAQVRDAANHIVHSF---------------------------------------DGTAPR--LAFALDSDEEGGDDGA------GDG----DEAG........................................... 823
18 -16.000PF05701.6; Q9FWW5_ARATH/24-519; Plant protein of unknown function (DUF827 topsan)  ali follow..  11  1...................................................................................................................................................RAPFQSVKAAVSLFGEVAVSKQRSTPR-RLSSESVCDKETQLMLVHKEFMKIKQKLDNAE------------STRSRALDDLSKAKKTMEDLSNKLETVNKSKQSAIDTKETVQQREEQLEHDKC---------------HGSPPHHHELDVAREQYISTTVELDAAKQQLNKIRQSFDSAMDFKATALNQAAEAQRALQVNSAKVNELSKEISDMKDAIHQLKLAAAQNLQEHANI---------------VKEKDDLRECYRTAVEEAEKKLLVLRKEYEPELSRTLEAKLLETTSEIEVLREEMKKAHESEMNTVKIITNELNEATMRLQEAADDECSLRSLVNSL-RMELEDLRREREELQQKEAERLEIEETKKLEALKQESLKLEQMKTEAIEARNEAANMNRKIESLKKETEAAMIAAEEAEKRLELVIREVEEAKSAEEKVREEMKMISQKQESKKQDEESSGSKIKITIQEFESLKRGAGETEAAIEKKLATIAAELEEINKRRAEADNKLEANLKAIEEMKQATELAQ........................................................................................................................................................................................................................................................................................................................................................................................................................................... 496
19 -16.000PF15324; H0UVS3.1/99-1343; Hedgehog signalling target  ali follow..  1....................................................................................DDIFISQYSVGQKDLRTILKQKAQS-KEVKVHLLDDAG--VEKVAAPPEARGSPSGIDSATAVAAATAAAIATAAPLIKVQSDLEAKVNSVTELLNKLQETDKHLKRVTEQQTSIQNKQEKLY------------HDHEKQMNVF------MEQHLKHLEKLQQQQIDIQTHFISAALKTNTFPPASTLAPRAMEKHSREPGCPFVGGSMLSSHEPFASKQATLRKVE--DTYFDEQESPLETPAPRRFAPVPVSRD--GEMPKRENPMEEKENMEKSDYKGNTRLLGQILNNNDSSTRKSESSDITSLSRSKLGWNPERRHRFPSSGEPGTAIVTVQKPNDVLQDLGQKRKETNSVLQAKRISDNVELADLPQSSCKLQTTNTRSVLKDAEKILRAVQNNKKMLEENEAIIRAKDGAAMYSFINALSTNREITEKIRIRKTVDEWIKAISAEIQDELARKDFEQRRFAQKNQRTQKAQIMSKDIKANTQDKTVNKSVILK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 483
20 -15.900PF13779.1; A9D7X3_9RHIZ/37-855; Domain of unknown function (DUF4175 topsan)  ali follow..  11  391...............................................................................................................................NPLAAAVVEQRGVLALDAQNLPRVFDLHDALTIAPEETIPDLSHYLLLQSVRGRLENARSD-EDLHAAIDYMWGVALQLED-GNLSLAERRLRDAQNALAEALENGATDEEIAQLMDELREAMQEFLQELARQNQNNPASEMQQAMPENMLRQRDLDNMLDQIENLARSRDQAQQMLQELQRMMNNLQAGRQQRQQQQGGPMRQQMDKLGELMRQQQQLMDETMRADRDRQSQSGEGRDRQEQGQNQPGQGQDQGQQGQGSQSLEEMLGALGR-SQQELQDALGQLQRDLEGMGINPSEGFGEAGEAMGDAAGNLQQGQTGQALGDQGRALQALRQGAEDMMNQMMQAMGNQQGDAEGEGPDQNGNRSADDRDPLGRPRATTGPDFGSRVQVPDE--IDIQRAREILDAIRKRLGDQLSPEVEKRYLERLLD......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 819
21 -14.800PF03999.7; PRC1_HUMAN/37-615; Microtubule associated protein (MAP65/ASE1 family)  ali follow..  1..........................................................................................................LQRTEVVKKHIKEL------LDMMIAEEESLKERL------IKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQ---------EQDQELCEILCM-YDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSF-ENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREA---SKAKVRKALQLEVDRLEELKM--QNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERAKQE.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 413
22 -14.800PF06160.7; EZRA_BACP2/3-562; Septation ring formation regulator, EzrA  ali follow..  12  103...........................................................................................................................LTHIEDLLSAADSNIEDI------LKEIADLVTSEEQNRKDIEKVKEQYQTVKNLLAYSHLYGTLYDKMEQDLDEAWEGIKQYEEETENGNYMKARKILLEQDRRLDQLQLYINDVPKLIADCKQTVPGQLTKLKDGYQEMSEKGYKLEHIQITKELETLNKNLEEASSILQMIDDAIETLYDQLEAEVEAGQEIKSRMPELTEAFEKLEQDHTQTKAETALVKESYKLTAGELDQQKAFEKRLEEIEKLMKQIREKLDRDHVAYSLLMDEINQLETEDAKALHDTFKGHLQSLRKEELQARETLAELKTMLTDTVRQLHKSNIPGVPAEMKERAEKAQEMIHQVHEQLENLPLNMPAVNQQLKEASDTVRNVVDETEEMLSKVDQIERIIQYGNRFRSQNHILSEQLKEAERRFYAYDYNGSFDIAAAAVEKASPGAVQKLLAQQEK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 560
23 -14.800PF07888.6; Q7ZTT2_DANRE/1-545; Calcium binding and coiled-coil domain (CALCOCO1) like  ali follow..  10  63....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EGYQKGADANCSVAFHPSYLPIPGVEEYQFVYVDGRGDVCAISSQFTFAAPRPLDELVTLEKSGEGEEDGDDLLLVVPKALILQNLLEGCQRELHELHKKFEAVNGDVENERQRWKTDRDEFEILRSDMRSQIEQLKTNLRHSTEKTEELERKHKEAQSSSESMSAEFNALLAERAENQQRIKELEDSATLTQQKQDIEAELERMKERVKKMTIQRRDEETERI-DLQLENEQMHADLRTLQERLEASERSTGALRRDLSELGSLQSHSHAELHQVRLQSAQMSLQLSQANL-----------ALREGQSTWAQERETLRQSAELDKDRVQKLSRELQKKEEWLQEERSEREKLEVELGIEKDCNRELRASLRALQKEQEQHQL--EKQELLDHIHVLELRLDTETDAKWAEAAATPICQFAKSYLHRA....................................................................................................................................... 478
24 -14.700PF15254; G1T8F1.1/39-892; Coiled-coil domain-containing protein 14  ali follow..  11  327...........................................................................................................................VNQTAEKVTTIKYFLGELKAAEQEDSEIQRLITEVEACVSELPAVSGNTNIQVEIALAMQPLRSENAHLRRQLRILNQRLREQEKTKKTTGSVECNLELFSLQSLNMSLQSQLQESLKNQELLQSKNEELLKVIENQKDENKKYTSIFKE--KDQTILENKQQFDEITKIKIELEEALVDVKSSKFKLDTAEKENQILGITL--------------RQRDAEVARLRELTRTLQNSMAKLLSDLSVDSARCKSGNNLTKSLLNIYDRQLQHDPAPAHTSIMSYLNKLETNHSVAHLEPLSTIKNEETTEPDRPYENVLPSKGPQPRNTSG--REEEPASGIISALSKQDSDAENETLTVIEDECNLDSTVYIPFVRSTSKMNSPLSK-----RLSPQPQMSVAITQLVGNSGLVSETEKKLCAHAVTCSSRQEVEDAHEKLSRTADTEDKQLLKKIKEAIGKIPVARED........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 776
25 -14.600PF05667.6; CCD22_AEDAE/1-554; Protein of unknown function (DUF812 topsan)  ali follow..  10  277................................................................................................NNITVETKPGKTPLESLQEEIDALQQEIVQHSEEGVQLESSRKET------DESIEEYRKTIVRLKEEKKIKERTHILLEDPEVNVKKLEAIIAAGGERMKKLQDQWDAHRIPLV--------DTLEAYRLKNSDKLSKSQQVLDQIESTRQKCEEVVIDLQTKGAMYARLQKEFEKL---NKTVSRTAYTSRILEIIGNIRKQKNGIDQILQDTRSLQKEINNITGQLDRRNAKKDEHSKRAYKLLVTLHSDCEELIKLVQETGAIKREVRDLEDQIENEKGR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 553
26 -14.500PF09787.4; A7USX6_ANOGA/12-516; Golgin subfamily A member 5  ali follow..  95.............................................................................................................................SKPEPSYSIEQELAAI------KIVLAEIKAERDELKSELDSTLSQQLSNGETESKLLDLEVLCQNLSEEKMALAGKLLSLEEANGKYV-----KSISELESTIAKHIQSEQELNSKLDMARLETENALTELQQYRVRAHATLQLKEKTRTDSTDSTDSKHSNAEQILQIELEQTRQEKANLAEELTSLNDRMKQREAQWMNAEEKLRVTVHALEQNVQRLQ---QQILLDADKFSVLEDDFKLKQRELASVREDLIKQRTSFTLRLHEKESENSKLRNKIHTRPVSPLNDQEDRLASLTQSLVQKQ----------------TALETVTVERNALRIQLEKLENQYRNTASQVRQQRAV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 436
27 -14.000PF08580.5; Q6FY01_CANGA/41-592; Yeast cortical protein KAR9  ali follow..  10  1.........................................................................................................................SSIEDLCDVLEWITTQMNRI----------------LEIFPQIIDSTGIEVSSLLEYLDWLQERKELLFELVNDINSIGPFLSDILEGIEANLNTDPNKSLDEHEMHL----------IDLIERCSTLRDDLDPWLNKLRKLLDATLEFKEIS--NDHMDGLDKVVSENIQSCFDIQEERFTSPVRHAPSFTLEQIVDLLKQN--------------SDSNAISVPTFNKQEKLISERFLELRRSVPAIEKSLTDILPN------------------------RIDNFARRDMTNIDSLAEFLRDKYKVLMKKYEFMSSEISELNAELIDKRWNILFVNLNHEINFILDDYEKLKKKLNSVEEIGINVQIREKMSHQ----------------------TQKSLTIERTFKVIFKAQEFSLLDAGIASKTNEMKNRWEKVRVDDKLLRSVSVDSGPEISSVTKDFES............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 380
28 -13.700PF03429.8; Q9RQF5_ANAMA/1-720; Major surface protein 1B  ali follow..  3.................................................................................................................................................................EDDKQQQQNQSDVVQAISAVFQRKSAELQRLNDFIKGADGTLKNVH---------PHMKSLEALSKQLSE------KIAAEAAAKADAKYESVGLRAKAAAALGSLGRLFRSGSKGGYTPQDIDALPFMDEAPDTGEKIEVPAGEEQEFGKAAAWGLAGFKRTVDESLEMLDRGMHMLAEGQAQISQGIADKST-----ALVREGLETSRLGAGLCRNGLVEASYGVSYANKTMGKYAGKGLEKCKNKLDDACHKWHDALNEIESLRTAIDAKAEQQVEGEAWSPEGVSANTFYRGLHKIGAAIAVAAQATWEGLAMTGKFMGAVAKLAGAVSMCVAAYTAAIAGVILPA---------GIPLAFMGPESKLAEYVDRAASYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAVNQKFEEINATL------------------------AREGTDIAQGIKETYKSIGDAFKSVNTGIAKWTTDKWTAALAGYASVEQLEE-AKEADRAQAEQRAEAQAMTERVA-------------------------------------------QERAATVAAGTETIKTIVSDMCNELAQICGLSQAERDALVQSFIP---------QPPRTTKEIVSQMCNSVKSAFGSISHITNVIRQAGKDAQKIDP---------QVKVAEISPETIYAMSEALYALNMQESAAINNALLEAVNDSSKDDQAIVTDLINATIEVCTEQTNTLAGHTAEVQAGLEAAGIKLDDAHTTPEAKELAQAAEGLATAVNEASAKIQSLNQQESQIAQGGQHAAQQQSSGWSR................................................................................................................................ 720
29 -13.300PF10168.4; Q707M9_XENLA/4-726; Nuclear pore component  ali follow..  462...................................................................................................................MICITCDFECIARPLLTTIRPPSPPLLCSQIDKSSTEILPHVLADVKGPFIHIRGILRRNSANPLLLNSSSKDSSPPPEECLQLLSRATQVFREEYLLKQDLAKEEIQRRVKLLIA---QKEKQLEDVRYCREERKSLTETAEHLAEKFEEAKERQEDLIN-----RLKRILRSFHTQLPVLSESERDMKKELQATTEQLQHLGNCINQVKRKMSYQEKQMEKGKSPRKSLTLSDYQKKNIKTVLKEHGEHIQEMVKQINNIRNHVN.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 722
30 -13.300PF15358; D2H7U7.1/26-586; Testis-specific serine kinase substrate  ali follow..  102..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DITEILSGVNSGLVRAKDSITSLKEKTTRVNQHVQTLQSECSVLSENLERRRQEAEELEGYCSQLKENCRKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQRQLQDEPRRQEAELQELEQKLDAGLSRHGLGPTAQSPGCCGPPGSPNEPPRPRSMAPGGWGMGPRAGEGPIVSEQEMQKVSAGLEELRRVGQG-REVSSLTARWHQEEGAVQEALRLLGGLGGRLDGFLGQWE-RAQREQAQAARGLQELRGRADELCTMVERSAVSVASLRSDLEGLGPVKPILEELGRQFQSSRRGSDLSMNLDR-----PPQGSCGRCASQGPQLSTESLQQLLERALTPLVDEVKQRGLAPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLA--QDEALRAKNLLLTDKMKPEEKVATVDYLHLKMCSLHDQLSNLPLE....................................................................................................................................... 536
31 -13.200PF07902.6; Q1CPP5_STRPB/1-621; gp58-like protein  ali follow..  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SRDPTLLIDESNLTIGSDGRAYYTFKADGDTKSVKLANNKCIGTTRFNQLMIERGGKPTNYVAPVVVEGSGESTGLFKNLEGALSQLKELNLELTDTVNSQLWAKIKLTTNGMLREYHRDNITEIVESANGIATRISEDTDKKLALINETVSGIRRDYQDADR--QLSSTYQAGINGLKATMANDKNDLKAVIQATAQGLSQ----------------KYDDEIQQLSA-TTSSGTTEAYESKLADLRAE---FTRSHQGMRTVLESRISGLQSTQQSTAYQISQEIKNREGAVSRVQQDLASYQRRLQDTEKNYSSLTQTVRGLQSTV------------------SAPNRGLESRVTQLAGLIEQKVTRGEMESYIRGAGDSIMLAIKGKLPQSKMSASEIVSAINLNGYGVRISGERIA........................................................................................................................................................................................ 387
32 -12.900PF15742; F1SF94.1/171-554; Domain of unknown function (DUF4686 topsan)  ali follow..  11  2...........................................................................................................................RPSGDRTKSQPQEELQQL------RQDLHRLQVLCSSAEKELRYERGKNLDLKQLQGESLKIKTELKQAQQKLLDSAKMCSSLTAEWKHCQ--QKIKELELEVLTQAQSGKSLSSLEEALAREKSNVAAAEEKISDLQQKLEHAHKVCLAETCILGKKQLEERIKEAMENEAKIKQNYQEEQQKRKLLHQNMNELQNQVKTLQDKERQLKMTNVQQQLRIQQQEAQLKELKNERRLCDEHLKSNQELSEKLSGLQQEKEALGRECGRLLKQLDVHVR-NYNEKHQHHKAKLRRVRDHNTNESIETLLEVECSDIVKCEPPKNEEEKEQKQVIAQNDTLSLEKRKLREQLVRQEGIIDKNRWMLSSVQKRVLFLDQENKHFLENNLQ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 383
33 -12.800PF10212.4; KRLAQ_CHICK/256-770; Predicted coiled-coil domain-containing protein  ali follow..  10  1.........................................................................................................LAGQALSFVQEIVTALLNF--------TYTEQKAQIFPIDSATDTISPLNQKFSQLHENAFYVRPLEEGMLQLFESITEDTVTVLETAVKLKAFSEHLASYLCFLRKI-----LPYQLKSLEEECESSLCTAALKARNMELHRDMKRLTAIFEKLHTYVSLLALPSTKPEGLLR--NYSLVFTNIAASLHGSHDILKDISKHYSQKATLEQDVPTATQKLVTTNDCILSSILSLTNGVGKIASFFSNNLDHFTSSLSYGPKGGTEFISPLSAECMLQYKKKAVAYMKSLKKPCADSVPYEEALANRRVLLSSTESREGLAQQVQQSLEKIAKLE---------QEKEHWMLEAQLAKIKLEKENQKLKNSLSGHLAETVQERSVLSNTAEQKEETTEKSQREPIKTTSLIGMLTITTDNEKVPDVESREDLIKKHYMARIAELSHLQLADSKSVHFHAECRALAKRLSLAEKSKESLTEELKLASQSISRLQDELMTTKRSYEDQLSMMSDHLCSMNETLTKQREEIDTLKMTSK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 515
34 -12.200PF14817; B5X4P2.1/5-647; HAUS augmin-like complex subunit 5  ali follow..  84.............................................................................................................................ELQEQIEELRVELNHL------DSQINGTEAQLVTEEESINRSWEMVEENQCLQAFKQRCMKERHSLSEDIHKISGHSQVLEQLSRRAE--MKVVFGNETSNSSGDHLNPSGAEPKVLRNVRELCDERLQFFQSLQESELNMTSSTATHLTREQRTALFRHWLSAVEDLLQCYPPNQVLSALQYLALGQEMTLEEMLASLDVARDVAALRFRYESNHLPDISKEEEELPPVKSLLQSAWEEVEQSLMELAQTRSRIQLLQTQLHA--------RKKEAQLELIGGESQTEALSQSVFKLEMQCGIQAAVRNSLR------DQCVQMEQHARDRQEDLRNLRSQWQNIMDFRQLGDVRQEQIRGLIKGN--------SIAKTELTRVHKEIGQFVQGKLVPQFAKVLSAANRLRNSVSQEARQFGNVSLLTLDRRIIEGEQRIPAAWLSIHRLHSLPFHNLCQSLAFPMYRAPEELYTQALSQHLELRFLRRLLQLHSSSLTNVEKQGALLPAPDQQLLRVLEEDKELLKSLLPKVRELAQRCSQGLCYGYQVKTAISH............................................................................................................................................................................................................................................................................................................................................................................................................................................. 617
35 -11.900PF09728.4; Q5RIN4_DANRE/94-406; Myosin-like coiled-coil protein  ali follow..  11  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KGLGKEAASLLQSLNKLGSPEEKVEMVLKKYSELVDEHRTEKKQLEQFQQRQGLLVKQRDQLQEHSRAILARSKLETLCRELQRHNRTLKEESLQRLREDEMKRKEITTHFQSTLVDIQSQIEQHSNRNNKLCKENSELAGKLKTIIEQYERREESLEKIFKHRDLQQKLSDAKLEEANMLLTQAEEKHKREKEYLLKEAIDKTKKYCTLREQELQMKKQLVLYSQKFDDFQNTLAKSNEIYVTFKQEMDKMTKKMKKLEKETRFESCNKALVEMIDERSEKGKEFELFTLKIDRLETLCRALQDE....................................................................................................................................... 312
36 -11.700PF13476.1; C4P4D4_ARATH/25-232; AAA domain  ali follow..  12  24ITGQNGSGKSAILTALCVAF--------------------------GCRARGTQRAATLKDFIKTGCSYALVYVELKN--DAFKPEIYGDTLIIERR--DHQGRKISSRKEELRELVEHYNIDVENPCVI---MSQDKSREFLHSGNDKDKFKFFYKATLLQQVDDILQSIGTKLNSANALLDEMEKTIKPIEKEINELLEKIK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 208
37 -11.300PF04582.7; Q9DPB5_9REOV/1-326; Reovirus sigma C capsid protein  ali follow..  12  10.......................................................................................................REVVSLILSLTSSTTTNPGDLTAVYERLTNLEASTKSL------RQSLSSIVSDLSDVSVDLQDTT---RALDDAIATLKGLNTTVAALQNSVASLSSTVNGLT------------DISSAHSEALSFLRTTIDGNTVAISNLKGDVSTNGLNIADLQNRMKSLESSTSHGLSFSPPLSVADG-LDMDPYFCSQRSAEAKLMQFQWMAKGTSGSSDVIDMTVNAHCHGRRTDYMMSSTGGLTVTSNAVSLTFSLDYITNMPSDLSRL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 263
38 -11.200PF15905; E9Q837.1/14-339; Hyaluronan mediated motility receptor N-terminal  ali follow..  11  66............................................................................................................................QKNDKDVKRLEKEIRALLQERGTDKRIQDMESELEKTEAKLNAAV---REKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKREKMRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETE--KLLEYIQEISCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENITFSKQIEDLTVKCQLLETERDNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 325
39 -11.200PF06818.10; Q4RYH9_TETNG/478-682; Fez1  ali follow..  1..................................................................................................................................................SKWEVCQKSGEISLLKQQLKEVQ---GELAQRVGEIVSLRGQLRETRGELTNTQVLLQEAH------------GTTRTRTLELEVCENELQRRKSEAELLREKAGRLEAELAHLKDALASQGPGNRQCQVFPEDQEQLLARAQEPSGGEVLQNMSVKMDRMRAELSYEHQRAEQQMSSFE--------------EERRIWQEEKDKVIRYQKQLQQNYVQMYRRNRELEQLLQE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 205
40 -11.100PF09789.4; Q16UI1_AEDAE/24-343; Uncharacterized coiled-coil protein (DUF2353 topsan)  ali follow..  10  1...................................................................................................................................................HRKLQSKVEALKIMRNELEKYR---SERDQFKLMAETLQMRYSAMKSSLNSPEFQAAGFGHSSAVSLLVNQTRERNISLSEVEALRQRVHELEGDIDVLRTKNFDLQAAFNKMKSTEETKLRDRKGIVWDEEKSKLIAQMETLKKKNAQLQYDVRSLLDEKEDVVMERDAYKCKAHRLNHELSVMLKGDQSQQKI-VDVDGLILENKYQQEKITNLENELELSRQSATKYKNMLDTKRKKGIIKLGTNNNQRVMSHSQVKDLLERGTVEELPLKAATISELKS-------------------LCLALLDNVNDKSLALSHQKKTNKLLAAKITELEQRILAL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 320
41 -11.100PF14662; C9JGW3.1/157-349; Coiled-coil region of CCDC155  ali follow..  12  1............................................................................................................................................................................QATADLLSSLEDLELSNRRLVGENAKLQRSMETAEEGSARLG--EEILALRKQLHSTQQALQFAKAMDEELEDLKTLARSLEEQNRSLLAQARQAEKEQQHL--VAEMETLQEENGKLLAERDGVKKRSQELAMEKDTLKRQLFECEHLICQRDTILSERTRDVESLAQTLEEYRVTTQELRLEISRLEEQLSQTYE....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 193
42 -11.100PF16043; A7S4W5.1/475-727; Domain of unknown function (DUF4795 topsan)  ali follow..  11  1..............................................................................................................................MQNMKKTLSMQQEDF------KKDMEKNKKAIDQLSRELSLFRAARKA-AEGFNAVHHVHSMVLELQTKHDKMMATTAELV---------NEYNRREKVLDELA----------DSIDKLEQKKADKQDVNKNIDIKANKEDLESKV------------SMNQFDESFNLLDRGLNEALEKMGNQMTIEDALKETLMDLQSKLTLKLDR--------NELDNLRAQLESRIKEVQVTRTVIQVKPEDGEPAGFRRN.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 212
43 -11.000PF15934; B4NYC9.1/468-698; Yuri gagarin  ali follow..  1..............................................................................................................................VLREIADLICKLGSM---EFSYNEIYDESSRENPFCTTIAELFELRSQ-QKHTALNEHLACQIQGLEDNLKDRDNQINQLQSMIKSYSDLTENSRLKGEIHDLKL---KNCDLSRQLRELSSLMRNQEDQRVELCSKYENLMTNFEDQ--CQELKGAKRKVQSLQSRLDQVEKLQDELRTERKMLREEVIALKEKEAVSA-----------------GRERALQEQQKIGHLELEKMRNHIRNMQDHLQLDDIR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 230
44 -10.900PF13558.1; A3YC50_9GAMM/971-1061; Putative exonuclease SbcCD, C subunit  ali follow..  18  31................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GTGSGGEKQSFYVAIASSLATAWGTLSNPGRALLDEAFDKLDEENLKNAMDFMGD................................. 90
45 -10.800PF09726.4; Q4SIM5_TETNG/2-648; Transmembrane protein  ali follow..  157........................................................................................................................................................................................................................................................................................................................................................................................................................................................................SYKMRLRKQKEVQKENEFYMQLLQQALPPEQQMLQRPEKETEEVTKGISEVEPSVTSQNGAPPGKKSSTLQLPELEYREKAKDSTGKEGKKVGINNNSIIHLDSKLQEAEYIENYAGAKRLNNDLAGENTDSNTHS------TSKEEMAGTGKNFKYNSGGGANISNSSPRNHSSSNGSVLSGSTSKNEKKQKGAGKAQKDPVENCIPNNQLGKPDALVRLEQDVKRLKTDLQANRQLESELRSQLSSLSSQDRSLRSELGPVRQDNELLQNKLHSAQAKQKDKQTISQLEKRLKAEQEARTLAEKQLAEERKRKKMEEATAARAVALAAATRVESTDSLRSRIRDLETECKKLTMDMKLKEEQIRDLEGKCQELRKYKENEKDTEVLM---------SALSAMQEKTQHLENSLSAETRIKLDLFSALGDAKRQLEIAQGQIHQREQEIAELKQKIAEVMAVMPSLSYSSDGSNLSPV--TPHYSSKFMDNSPSSLDPNASVYQ....................................................................................................................................................... 645
46 -10.800PF04108.7; ATG17_PICAN/6-396; Autophagy protein Apg17  ali follow..  12  2.......................................................................................................QWVADARANLAHAEQVCNDANMYLTSTSEKLRRREMKVPKLIYYLDALKQQLRLLEIIRDSLVLNLNGVME--KRAALQSQLLKDVDRLHQTIDTLKNTVVVFDGQTTLYEYISE-SGVEELFNGVSQNLKDIQTLIKG-NRTDALLIRLTSDLDHLSNELNALDSKFRDMRLVDTQSSSIDPISKLLEINAELEHDMVAILTSFNNHYDQCEKGEAILKDPAVPQDEKDELVSVLQNDVEELPEAQRSLTSNAEIIKKNCKEVMKILDIFEDYFQRVETYVCELQEYGESKLRVQLKEFSDINTEVSRKLEIAQTHQDELVQYNSDFQQFVRSYYSL------ILELDRRMRVNEHISSAIDNFRSTISNIVEKDHEKRME................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 373
47 -10.700PF04163.7; KAR5_SCHPO/1-544; Tht1-like nuclear fusion protein  ali follow..  155......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELSIEVNMNVTLVQKQLEMVILHLRNFESVTDKMNQRIDKFDGKFNSVIENSFKDINFRVNQEIMGLVELQNHQQEGMVQQKEILSTIKQLKSEIFDINSFFANFIEESAGYSN----SLIEKLNEKFTSENAIALSAIGKYTSEFSAFMEKRIKNLITTTEDSLQQSVQSNIDFVNSGFQPLYDLTIQLKEELQSLKRLSSEQQNLQH-EQILQWKSDFLNVSKDHLKVLQQLRPLIDIVEKFMNVYFKGLS..................................................................................................................................... 403
48 -10.700PF03915.8; A5DRI1_PICGU/262-666; Actin interacting protein 3  ali follow..  10  75............................................................................................................................SESDSSNQELLKAINAL---RQVQELQYADLAAQIGNLALQPKKVNETTKEGTTQPTNVLGIEEITSLKQQFTSLRSMQAQYKRDVE-----ADISSVIAKVKAFQEGGLNVSKSSNR-AYMEGCHSKLSEESDILLTKVDDLQDLMEAMRKDVAQRGVRIGEKQLKNTNREIQAAKNSLKEMSQYITRERVVWKRIWES-----------------ELDKVCEEQQFFNLQGDLTVDLEHDLKKIEKTFDLIEQCSLEQSKQNAQRRNKFFVPLMEPGKSLDKMKDAILTSVVALNPDHDRRLDAITRAEKLRDRERELMRKDQFQEELEDFVGDKKFKNAVGIDEVERLRRERDS....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 405
49 -10.600PF01044.14; CTNA2_CHICK/18-867; Vinculin family  ali follow..  1.....................................................................EIRTLTVERLLEPLVTQVTTLVNTSNKQNFLEKGDQIAKESQDLKEELVAAVEDVRKQGETMGTMVRAARALLSAVTRMADVMRLLSHLKIVEEALEAVK-NATNEQDLANRFKEFGKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISNAAQATSPT-DENKGHTGIGELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRKRIVAECKRAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVKVAQDNMDVFKDQWEKQVRVLTEA---------DDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYETGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPD--SACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKA...................................................................................................................................................................................................................................................................................... 818
50 -10.600PF00261.15; Q805C4_TAKRU/12-248; Tropomyosin  ali follow..  12  3...........................................................................................................................IQTLQQQADDAEDRAQVL------QRQLDSERELREKAEGEVAALN---RRIQLVEEELDRAQERLAVALQKLEEAEKAADESERGMKVIE-----NRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAELSECKASDLE-----EELKNVTNNLKSLEAQAEKYSEKEDKYEEEIKILTDKLKEAETRAEFAERTVTKLEKSIDDLEEKLSSAKEENLGMHQVLDQTLLELNSL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 237
51 -10.500PF03207.8; Q44722_BORBU/1-254; Borrelia outer surface protein D (OspD)  ali follow..  11  3...............................................................................................................KLIKILLLSLFLLLSISCVHDKQELSSKSN------LNNQKGYLDNEGANSNYESKKQSILSELNQLLKQTTNSLKEAKNTTDNLNASNEANKVVEAVINAVNLISSADQVKSAQKNMHDLAQMAEIDLEKIKNSSDKAIFASNLAKEAYSLTKAAEQNMQKL-------EQQKISESESESDYSDSAEIKQAKEAVEIAWKATVEAKDKLIDVENTVKETLDKIKTETTNNTKLADIKEAAELVLQIAKNAKEIVQEV...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 251
52 -10.500PF15066; F1PHS8.1/30-557; Cancer-associated gene protein 1 family  ali follow..  11  322............................................................................................................................GKLEHTNRKQQSQIQDL------QSSNKYLERKVEELQMQDTKQQVFVDIINELKAKVEELIEDKYRMMLEKSDTNKTLQNLH------------KVLTHTQNRLQEVKNEKETLQLELKRIKGNFVHLQEKYMTAVQQRDKTVSLCLQM--NRTISEKEEEVERLQQLKGELEKATTSALDLKREKKTLEQEFLSLQEELQKHKKENLEERQSLKLRLEKLLAQVS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 528
53 -10.500PF12532.3; B3QEB7_RHOPT/422-613; Protein of unknown function (DUF3732 topsan)  ali follow..  12  1............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELISKLESEIEDLTVPPI---------NERQELFTSALDEAIQDYISLTRDALGNYGEYRSAFNYSEKKLHL----RKPRTASTENVGSSSN--LHLFLFLGIHELIMRNNGHVALIIDQFSRPYDVAKVKLALELLNQFGKDFQIIVFEH..................... 167
54 -10.400PF04849.8; Q4SVU4_TETNG/101-401; HAP1 N-terminal conserved region  ali follow..  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EYICLPSHGGKAKEVEEEEMDEEQQIGRSSMTTKLLWLKFLRVLCADRVGQMTKTYSDIDAVTRLLEEKERDLELAARIGQSLLKKNKALSRNDLLEEQVEHIREEVSQLRHDLSMKDELLQFYTNAAE-ESEGESFTSTPVRPADSNVSTPTFFPLDSLQKKLKDLEEENKSLRSEASHLETETISYEEKEQQLVH-----------DCVKELRNSNLQITSLSEELARKSDDASRQQEEITHLLSQIVDLQKKVKLHALENEELTQHLGAAKDAQRQLTAELRELED--KYAECMEMLHEAQEELKNLRNK............................................................................................................................................................ 300
55 -10.400PF04310.7; MUKB_ECOLI/1-227; MukB N-terminal  ali follow..  13  32LSGGNGAGKSTTMAAFVTALIP--DLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQA-------VLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLY---GISSAITRSLRD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 219
56 -10.300PF10234.4; A7SE98_NEMVE/14-284; Clusterin-associated protein-1  ali follow..  5.......................................................................................YPRLISMENAEVLIWLVKRYDPNVELPMDVETEQDRVLFIKAVAQFMATKAHIKLNTKKLYGADGYAVKELLKVTSVLYNAKSNVTDDEAEPSDVTSLTFDISSRISDLKASRQLASEIT---------TRGAALYDLLGHEVELRDIRTRAIAKPLEVNELENGIKKSISLAQDDIRKTTQMLDNIASDEANLE-----AKIDKKKQELERNQKRLRSLESVRPAFMDEYEKLEEE---------------------LKKVYETYMEKHRNLSYMEQLLDDVNRAEQDRFE............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 271
57 -10.200PF06637.6; PLVAP_HUMAN/1-442; PV-1 protein (PLVAP)  ali follow..  48..........................................................................................VYGNVHVSTESNLQATERRAEGLYSQLLGLTASQSNLTKELNFTTRAKDAI------MQMWLNARRDLDRINASFRQCQGDTNNQRYMAAIILSEKQCRDQFKDMNKSCDALLFMLNQKVKTLE--VEIAKEKTICTK-ESVLLNKRVAEEQLVECVKTRELQHQERQLAKEQLQKVQALCLPLDKDKFEMDLRNLWRDSIIPRSLDNLGYNLYHPLGSELASIRRACDHMPSLMSSKVEELARSLR------ADIERVARENSDLQRQKLEAQQGLRASQEAKQKVEKEAQAREAKLQAECSRQTQLALEEKAVLRKERDNLAKELEEKKREAEQLRMELAIRNSALDTCIKTKSQMMPVSRPMGPVPNPQPIDPASLEEFKRKILESQRPPAGIPVAPSS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 441
58 -10.200PF13870.1; B4J5C0_DROGR/499-675; Domain of unknown function (DUF4201 topsan)  ali follow..  10  1..................................................................................................................................MSQKRNEISDD------RLYLISRKHTLGRITDKITKLEQINEDLC--MDDFINIQNQVAALDKKIEERNNDLKKLRLNYH-----TELHLTQHNREKALALDSKLDVAKLNLEIMQKKQDQLRECLYKAKLERSNIRKVHSDLSFQGGLLSMPALMFDYDETVERVRAKQASVKELKETFKHITQRILE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 177
59 -10.200PF10481.4; CENPF_HUMAN/1-288; Cenp-F N-terminal domain  ali follow..  10...................................................................................................................................................EGLPTRALQKIQELEGQLDKLK---KEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLM-----EICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQ------------QAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 285
60 -10.100PF12004.3; A5PF29_DANRE/580-1085; Domain of unknown function (DUF3498 topsan)  ali follow..  356...........................................................................................................................................................TAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLK-----GQEEQAQKMLLEYARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVSKQKIIDAQEKRIASLDAANARLMSALSQLKER..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 505
61 -10.100PF10146.4; Q17IP3_AEDAE/14-270; Zinc finger-containing protein  ali follow..  10  1...........................................................................................................................................................EAMKDIRSKTLQLEKVKLKIIREVENGDAEEKCLSEYRRELELLMQEKMSHV---------EELRQIHADINAME----------TVIKQAEENRIRSINMANRFHEEYVPLKTEVDTMRREYLGLERLPELHEEEGSIISPDRFQNYYTGSKALTAPTAAFARP........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 146
62 -10.100PF08317.6; Q754X4_ASHGO/431-759; Spc7 kinetochore protein  ali follow..  11  73...........................................................................................................................VKELHRRILDSQRLFQELEEQISNNPPFRNYFESSDEVKQLMKEQIVLIKSFARLEAKKVWFEWRCQHLKGIKSVLEENLSLVQ---------TEYAEVVARLNEISDI----HRLQALEQSLRHELELLRNGEKPMRVTTLADRLKIEKI--KSELKANMIKLNNTANLEEQKEAISADINALRSQIKDVREEISSLKSLVLKNKLHTAHDVSKLRLLFSQMQLF........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 287
63 -10.000PF10186.4; B2WCB9_PYRTR/2-373; UV radiation resistance protein and autophagy-related subunit 14  ali follow..  23.......................................................................................................................................................AYLEHPRIELAKTLIDLDGVEKHVKAIINGSEDKAIQHVSLTDSKGGLLVDRQECTNNLNWQRTKAETAEIQERLGNIS----------DHAHQLRQQMEATRKLLEAKRAANAQRKSDLSSATYG-----ESRRANELDKVQQKVKRLDYNADKMHHDTIDLRMQLCTTAAKLAGLKMQRRKTRDGGVKEVFNIGPGSRLRIYDLRDMNDVAPD.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 223
64 -9.910PF01496.14; VATM_DICDI/30-807; V-type ATPase 116kDa subunit family  ali follow..  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VDELGKLGLIQFLDDNEHVNLFQRNFVNEVKRCDDMEKKLKFFEDQVKKEPKLQKLLPDNMLSVVDDDSQMDELEGRFDELESELKQVNANQETLQRNYNELIQLRHVLTKDSVFFQENPNLIEGEGHEH------------SARSPLLAEDQHVSEVAKQGVKLGFITGVMNTDKMPQFQRSLWRTTRGNNYVKDARIEEEIIDPQTGEETAKTVFIVFFQGERLQQKIKKICESFGANIYDSFERSNLLQKVTVRITDLYEVLQRSKDHKRQTLAGIVPLYSWKKKVLLEKSIYHTKDKIEEIQLALRTATTR------SGALVPSVLSIIKTEGSPPTHFETNKYFQEIVN-HYREV------NPAVL----------------------TIVTFPFLFGVMFGDVGHGALLLL--LISLEKKLAGKKLNELIQMPFDGRYVLFLM...................... 437
65 -9.880PF04156.9; Q50FQ1_CHLTR/23-216; IncA protein  ali follow..  68.........................................................................................................................................................................................LHLYQDLQREVGSLKEINFMLS---------VLQKEFLHLSKEFATTSKDLSAVSQDFYSCLQGFRDNYKGFESLLDEYKNSTEEMRKLFSQEIIADLKGSVASLREEIRFLTPLAEEVRRLAHNQQSLTVVIEEL....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 194
66 -9.810PF15450; G1PIP2.1/55-586; Domain of unknown function (DUF4631 topsan)  ali follow..  1.............................................................................................................................................................................................................................LASTTSVPEQ------DTPKRWKQLEQWVADLQAEVVSLRGHKDYCERATLSLL------------QELRQVQASVQLQDSELKKLKQELQQAAWVPEKEALE------------FPSPQNQNKMQALDKRLVEVREALTQIRKQQALQDSERKGTKQEANLRLTKLARKLEQEEQNREVACSALQRSQEEASQKVDQEVARLQAQVTKLG-----------------------------EEMSLRFLKREAKLCGFLQKSFLALEKRMKTSESTRLKVESSLREELESRWRNLQELAEERLQALRGQCKVGSSGWAQEESYLLEQCRGLDRAVVQLTKFVRQNQVSLNRVLLAEQKAQDTKGHLEE--------------------------SQAGELAAYLQENMEAMQLASEQARQETQSTLELLQEKRQALEGSVAELVTQVGDLNDHFLALSWRLDLQEQTLTQKLCEAKSEREGAER-----------------------------RSMEGLAWCRKEAQAYLREVRETVDSLPRQIEAVSDRCVLHKSDSDLKISAEGKAREFEVEAMRQELAALLSSVQLLREGNPWRKIAEIQGKLATNQIIKLENSIQDNKTIQNLKFNSQIKMRMEEMATLKECL..................................................................................................................................................................................................................................................... 532
67 -9.790PF13304.1; B1HP30_LYSSC/55-363; AAA domain  ali follow..  19  238.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................INWTMDSKGTVRMLHLACVM--VDAYNKGK----IFIDEFDTAFHVSICEFLMAIMNSKRNTSQFVVTSHEIELLD............... 309
68 -9.770PF04111.7; YDKA_SCHPO/121-497; Autophagy protein Apg6  ali follow..  10........................................................................................................DLLSSKTKVDHPL------VECAELLTEEMSKTLRAL---KEEKKMYFNYDNFLSSQTVHEENTAALDSEIDELMKQINEKEEKIEEISDETDKLQKLLRELD---------EEKEKVYAEEQEF----------YNNLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKMNVFSDIFYISHYSEPNGEGSIATINGLRLGRLPSQKVNWA........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 195
69 -9.760PF06008.9; P70570_RAT/237-496; Laminin Domain I  ali follow..  16.......................................................................................................RHVEMQAKDLRNQLLGFRSAISSHGSQMDGLEKELSHL------YQEFETLQEKAQVNSRKAQTLY---NNIDTTIQNAKELDMKIKNILTNVHILLKQIARPGGEGMDLPVGDWSRESAEAQRMLRELRG--RDFKKHLQEAEAQKMEAQLLLNRIRTWLESHQVENNGLNIRDSLNDYEAKLQDLRSVLQEAAAQGKQATGLNHENEGVLGAIQRQMKEMDSLKKYLTEHLATADASLLQTNSLLQRMDTSQ................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 260
70 -9.750PF03904.8; YP2A_STAAU/1-230; Domain of unknown function (DUF334 topsan)  ali follow..  2.....................................................................................................................................................RKGQLIMSMKDIKNNKENPN---TQMNSKSTGTPSSSTQNSLNNEELSELKRQNKLIVKYLAEIQ-----ENQKIREKEQKEITSELKEATKDFRDKSLKIRNDFVDVLQEKLKHVDTEELKDILGRGIYKVR-----EENDRMLQEVKRSHEHYQTRQKYLFTGIGAMLLVFMLFA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 165
71 -9.630PF06409.6; A6NCT9_HUMAN/1-331; Nuclear pore complex interacting protein (NPIP)  ali follow..  50..............................................................................................................................................RSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAKICKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHTYM------------EMFQRAQALRRRAEDYYRCKITPSARKPLC........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 212
72 -9.620PF13805.1; C5DXD8_ZYGRC/1-270; Eisosome component PIL1  ali follow..  11  53...........................................................................................................DLARKLSQLVSTEKGVLRSLEVVAYERRAAARQLSLGVDNDDDVSDVTDKLGVLIFELGELQDQYDQYRVTLKSIRNIEASVQPTRNRKEKITDEIAHLKYKDPH---------------------------SPKIPVLEQELVRAEAESLVAEAQLSNITRERMK-ELAEKFALIAGYGKALLELLDDSPVTPGETRSAYDGYDASKQIIMDAEAALE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 259
73 -9.570PF10088.4; B2UCR3_RALPJ/445-574; Uncharacterized protein conserved in bacteria (DUF2326 topsan)  ali follow..  37...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSGKKQGEISCFDIAYTLFADDENIPCMFLLNDKKELMHDNQLLKIANLVEREKTHIQFVASMLRDKL----PELNSDNFIVLKL 119
74 -9.560PF14362.1; D3CY45_9ACTO/50-394; Domain of unknown function (DUF4407 topsan)  ali follow..  89................................................................................................................LAILIGVVISTPLVLRIFEAEITTELSLMRSERDSTTQTDERGMRIKALEAEQKTLQATIDT--STDTVDVSTDPDVARIQKLVDTKQQQYDAAE------------QAVICENEGTCG--SGKVGRGPAYAEKVALRDRYRDELSVLNGQLTTAQATARSKATDTRGAAQNTAKGRLKTVETELTDLRTARTAAIANFRKENGKENGLLIRIE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 290
75 -9.510PF09738.4; LRRF2_BOVIN/31-326; Double stranded RNA binding protein (DUF2051 topsan)  ali follow..  11  3....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRVSGDTSSLIDPDSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVD-TLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPDGTPNG--------DVHQEPAVGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSGRDGTAGDLAELQNGSDLQLI-RDANRQISEYKFKLSKAEQDITTL........................................................................................................................................................ 296

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.