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Query: PF13166.1; Q63PW4_BURPS/9-780; AAA domain, from PfamA26U

Results of FFAS03 search in PfamA26U
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SFGCFSDFAWNAEVRDHGNNVAKFKKMNVIYGRNYSGKTTLSRIIRSLETGSISPRYASPSFSITISGAVITNNNIPAQGHDIRVYNKDFVDEHLAFLRDEQGHISPFAVLGSKNKEIEVEIDKLEDELGSVENKTGLRHSYQEKKKAHADKKKAAQDAQDELDKKIFDKANKNPTGIKHNSLYKDANYDVRKLKLDIKTVQDKKIAPLDDADRSSKVKLLSEVALPDIEKRLSFNSSLPALAKSTVELITKKIKPSAPIQELLNDAILQNWVKSGIPLHEATRETCGFCGSPLPADLWKRLGDHFNQESQDLEKDLDSVLTKISNEKTRIKNVVTVDRKNFYSANQATFDNLKADLDDAINNHEKSLQSLEDELNARKKDIFTERSTIDVQDNTVSISQKVSLVNELIERNNKTTTSLEEDQKIARNELRLSEISQFTIDIDLAGEEKKIKALEDQITKAKDELDAVEAEGKKRVDRVKELRTQLRDEKRGAEQVNQYLGHFLGHGGLSLSAVEEANTATYRFQILRGDQAAYNLSEGECSLVAFCYFLAKLEDIETKGKKLIIYIDDPISSLDSNHIFFVFSLIENYITKPIEDANGKTILDGNGRPTYRYEQLFISTHNLEFLKYLKRLTKPAKDSESFLITRKQSSSAIGLMPTYLRNYITELNYLFGEIYCCSDANNANSHYHSFYNFGNNLRKFLESFLFFKYPFSISDRTDHDKRIKMFFHDGTNSQAFVERLTNEFSHLGEFIDRGAQPIDCAEIAAVAKFVLKLast
1 -162.000PF13166.1; Q63PW4_BURPS/9-780; AAA domain  ali  100  1SFGCFSDFAWNAEVRDHGNNVAKFKKMNVIYGRNYSGKTTLSRIIRSLETGSISPRYASPSFSITISGAVITNNNIPAQGHDIRVYNKDFVDEHLAFLRDEQGHISPFAVLGSKNKEIEVEIDKLEDELGSVENKTGLRHSYQEKKKAHADKKKAAQDAQDELDKKIFDKANKNPTGIKHNSLYKDANYDVRKLKLDIKTVQDKKIAPLDDADRSSKVKLLSEVALPDIEKRLSFNSSLPALAKSTVELITKKIKPSAPIQELLNDAILQNWVKSGIPLHEATRETCGFCGSPLPADLWKRLGDHFNQESQDLEKDLDSVLTKISNEKTRIKNVVTVDRKNFYSANQATFDNLKADLDDAINNHEKSLQSLEDELNARKKDIFTERSTIDVQDNTVSISQKVSLVNELIERNNKTTTSLEEDQKIARNELRLSEISQFTIDIDLAGEEKKIKALEDQITKAKDELDAVEAEGKKRVDRVKELRTQLRDEKRGAEQVNQYLGHFLGHGGLSLSAVEEANTATYRFQILRGDQAAYNLSEGECSLVAFCYFLAKLEDIETKGKKLIIYIDDPISSLDSNHIFFVFSLIENYITKPIEDANGKTILDGNGRPTYRYEQLFISTHNLEFLKYLKRLTKPAKDSESFLITRKQSSSAIGLMPTYLRNYITELNYLFGEIYCCSDANNANSHYHSFYNFGNNLRKFLESFLFFKYPFSISDRTDHDKRIKMFFHDGTNSQAFVERLTNEFSHLGEFIDRGAQPIDCAEIAAVAKFVLK 772
2 -30.900PF13514.1; B5J9R5_9RHOB/33-1144; AAA domain  ali follow..  10  549......................................GQLRQIEQAEVEAQIRLEQADKRLEVLDKELTALDAAVGAAARQAGLTSTITSAEWLDWVARNSTATEDAQALFAAREEHQPILDRAEDLRAELSRLLTFEATDVASALTVARQVAEGERKQSENEARAQETLQQAKRNLR------KREERHQAALSVEAEARNAWYTLILEMLGDRIAPENLQASLEPLRELREHAKTRASAAQRVASMKVDQERFAEEVAALAKAYNLETLETAAETFSALKT----------RARSAHEAVEKLTGDIKEAEARKSKNSEKLREIKQAIEAIASGFPYSTSLTEIDELRTVVKRAQQVIEERAALVKLQRTVVSELGVNDIKAAREEMAALSLTDLEAAFENSKSDLERAEEELTQAIEIRVAAEQGV-----AQVTGDADIATLVEQKATLELQLEDSALEHLELSLGHYLASNSIRRYRDSHRS--GMMTATERCFASLTQGAYPSLITQVDKDAEVLLAVDCTGASRAAEMSKGTRFQLYLALRAAAHEQLVAQGTRLPFFCDDIFETFDEDRTSAACRVMETI---------------------GSRGQAIYLTHHRHVVDIAMKVCDT......................................................................................................................................... 1105
3 -27.400PF13175.1; A9A6W0_METM6/4-391; AAA ATPase domain  ali follow..  12  3KFRI-KNYK---SIKDSGDVYLSPDNITILAGMNESGKTSVLEALEDFNVGK-------------------------------------------------TVRESAKPICGNLDPEISLFFKLNVEELEKISKDISNIYLSNDFSKNIELEVKKVGSTYFLENNDIYSCLEDYNIGII---------------------------------------------------------------------------------------------------------------------NTLVEIENEINTLSKNIDVIFPTEFNSVEEFRKIMDQKIKDGKSKITDDFNEKIKTQLNALFDEAQKYTLYFLDIDKTLINYIENVVKKEYIPNFIIFKTYKDSKIPNIIPFANL----------------------------------ETDEFIKDLQKVSNLDINLIKSTDRQRKK------------NHHGAININLQEDYSKYWTQSESNLEITWDNNNVEFWVKEDNTSYTPEQRSKGKQWHLAFYIRITA---RSKEGKNNILLIDEPGLFLHAQAQEDIINKLEDASKTM---------------------SIIYTTHSPYLL.................................................................................................................................................. 388
4 -18.100PF02463.14; SMC_BACSU/2-1172; RecF/RecN/SMC N terminal domain  ali follow..  12  675......................................................................................................................SRELEDVTKRLAEMEEKTALLEQEVKTKHSIQDMEKKLADLRETGEGLRLKQQDVKGQLYELQVAEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEE------DIDRLTKQKQTQSSTKESLSNELTEL-----------------------------KIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSFLTSEMSS--STSGEEKLEEAAKHKLNDKTKTIELIALRRDQRIKLQHGLDTERELKEMKRLYKQKTTLLKDEEVKLGRMEVELDNLLQYLREEYSLSFEGAKEKYQLETDPEEARKRVKLIKLAIEEL-DEFERVNERYKFLSEQKEDLTEAKNTLFQVIEEMDEEMTKRFGRAELRLTDPNDLLHSGVEIIAQKKLQNLNLLSGGERALTAIALLFSILKVRPV----PFCVLDEVEAALDEANVFRFAQYLKKY---------------------SSDTQFIVITHR...................................................................................................................................................... 1149
5 -17.000PF12128.3; Q8EAA0_SHEON/1-1188; Protein of unknown function (DUF3584 topsan)  ali follow..  10  19...........................TNICGTNASGKTTLQRLVPVFYGEYPSRVVPSTRDSFE-------------HDSSYIIYERAIIQNDRTLLSTGSNRSELRAYARQDGEHSLRHIEKLAKAVHSKEGKMETVKSMIAAILEEDGVNPPSSRLNPQRVEAWIRESQLIQGFEVIRPEFEKLEQEFNQLLSAEMRLSSLSRGYRNDESLEADRLEIQQTLSKELNLKLRMKEVRDELNLDLSAAKGDVAKCEYELDAIEDQ--HGAFLDANIEQAKADLDMLPNWRADMENEKHQDIEAAYNARRSKIGEQLNRELEGLHSEQDKQREARDKQREVARGDLDALEAQWRSQMDAGKASFSEQEYQFKLNAAELKLRVDGVTYTEEEKLNLAIFDERIHRADEEQESCNAKVERLTSDERKLRAKRDQANEALRIASLRVNERQTALDELHHMLFPQSHTLEFLRKEAQGWEQSLGKVIAPELLHRTDLHP..................................................................................................................................................................................................................................................................................... 568
6 -16.600PF04094.9; Q8S5S8_ORYSJ/246-1073; Protein of unknown function (DUF390 topsan)  ali follow..  10  382................................................................................................................TVLDGLSAQMEVLQAERAELDAAWARVEEGRRSVEAMVEAGRKHRRHTSELEARRRDLAEIAREVEEERETALIATTVLNEARDDLRLQYGSRAAELEKDAARGVLDAAAARERRAAENEAASRQREEALEARATALEERARAKERDMADREAAV----------------------------AIREATLAAH-EAACAEEESALRLREDTLTERGRALEEAEAAAQRDSLFLREAAREEQARRNLEGARAKRAALDQRVAELEARAKELDARAHSGGAAVGDGDLAARLAAAEHSIAELQGALDSSAGEVEALRLAGEVGPGMLRDAVSRLDRAGRQAGLWGGRCAKYAANQGGLAQRLSEMAGTLQRLPEELEETIKSSSRLARGAVELVLASYQARDPDFSPWAALEEFPPGTEDGARAQVRDGTAPRLAFA--LDSDEEGGDDGAG-----DDPGAS....................................................................................................................................................................................................... 828
7 -16.200PF05557.8; Q9W6G9_XENLA/2-716; Mitotic checkpoint protein  ali follow..  10  169..............................................................................................................LQWKIMNQEMQIKTQETEKQELTEQLEIHRKKLQESNEKMQALHELQAQNADNEQKIKSKLSAQEQDAAIVKSMKSDLTKLPKLERELQQLRDENAYHREMKENNALLKEEVEGLRRAAERFNKMKEDLVGSEIEKEQLVKKLKLWENLEQSTGLNIRTPDDFSRQIMAVQQRELK------------LKEENMTIQISARMLETSRQQLQEELLKVQSGFLEE---------KKRREHQEALVRRLQKRVLLLTKERDGMRAILDSYDSELTPTEHSPQLSRRLKEAEDILQKVQDHNAEMETQLSEALEDAGIQKQKSELLTAELKVLKSQMGSSDQNISFTNEAMSALRLKIEELEAERGRLEEENKILEMRLESLNLQGCYDPSRTKVI............................................................................................................................................................................................................................................................................. 543
8 -16.100PF13779.1; A9D7X3_9RHIZ/37-855; Domain of unknown function (DUF4175 topsan)  ali follow..  8  393..............................................................................................................LAAAVVEQRGVLALDAQNLPRVFDLHDALTIAPEETIPDLSHYLLLQSVRGRLENARSDEDLHAAIDYMWGVALQLEDGNLSLAERRLRDAQNALAEALENGATDEEIAQLMD-----------------ELREAMQEFLQELARQNQNNPASEMQQAMPENMLRQRDLDNML--------DQIENLARSGARDQAQQMLQELQRMMNNLQAGRQQRQQQQGGPMRQQMDKLGELMRQQ-QQLMDETMRADRDRQSQSGEGRDRQEQGQNQPGQGQDQGQQGQGSQSLEEMLGALGRSQQELQDALGQLQRDLEGMGINPSEGFGEAGEAMGDAAGNLQQ-GQTGQALGDQGRALQALRQGAEDMMNQMMQAMGNQQGDAEGEGPDQNGNRSADDRDPLGRPRATTGPDFGSRVQVPDEQRAREILDAIRKRL----------DQLSPEVEKRYLLLD............................................................................................................................................................................................................ 819
9 -15.400PF09787.4; A7USX6_ANOGA/12-516; Golgin subfamily A member 5  ali follow..  12  102.............................................................................................................SIEQELAAIKIVLAEIKAERDELKSELDSTLSQQLSNGETESKLLDLEVLCQNLSEEKMALAGKLLSLEEANGKYVKSISELESTIAKHIQSEQELNSKLDMAR----------------LETENALTELQQYRVRAHATLQLKEKTIEQLKEQMSGSGRTDSTDS-------------------TDSKHSNAEQILQIELEQTRQEKANLAEELTSLNDRMKQR------------EAQWMNAEEKLRVTVHALEQNVQRLQQQILLDADKFSVLED--DFKLKQRELASVREDLIKQRTSFTLRLHEKESENSKLRNKIHTRPVSPL------NDQEDRLASLTQSLVQKQTALETVTVERNALRIQLEKLENQYRNTASQVRQQRAVYLN.............................................................................................................................................................................................................................................................................. 439
10 -15.300PF11398.3; Q6D3T4_ERWCT/1-377; Protein of unknown function (DUF2813 topsan)  ali follow..  10  10GFRGINRLS-------------TLDENNVLIGENAWGKSSLLDALSLLLAPTLPL------YHFDMQDFHFTPGDENSREKHLQI------IFTFCETAPGHHLSPRYRSLSPVWVEGNESLYRVFYRLEGEVDESQSVFTWRSFLDADGHPIPL----------------------------------------------------------------------------------------------------------------------------------------DNIDELAREIIRLHPVLRLRDARFMRRLRSGTLAATLDNSNE-----------------------------------------------------------KLAQQFEQLIRELVQNPQKLTD----------------------------------KELRQGLVAMQQLLEHYFSEQNATGNDRRHHRHARTHNGKSWRSLDNINRLIADP---------------------------------NSRSSRIILLELFSTLLQAKGSVVLDPLLLIEDPETRLHPIMLSVAWGLLTQL-------------------------QKVTTTNSGELLSLVP---------EQVCRLVRESSRVATYRIGRQGMNAEDSRRIAFHI.................................................................................................. 370
11 -15.200PF10186.4; B2WCB9_PYRTR/2-373; UV radiation resistance protein and autophagy-related subunit 14  ali follow..  11  1.............................................................................................................................................................................................................................................................................................ECDICGRDGSLSQPLHCITCARAYLEHPRIELAKTLIDLDGVEKHVKAIINGSEDKAIQHVSLTDSKGGLLVDRQECTNNLNWQRTKAETAEIQERLG------NISDHAHQLRQQMEATRKLLEAKRAANAQRKSDLSSATYGIESRRAN------ELDKVQQKVKRLDYNADKMHHDTIDLRMQLCTTAAKLAGLKMQRRKTRDGGVKEVFNIGPGSRLRIYDLRDMNDVAPDSLSASLAAVAQLLVRVAA.......................................................................................................................................................................................................................................... 241
12 -14.900PF10212.4; KRLAQ_CHICK/256-770; Predicted coiled-coil domain-containing protein  ali follow..  11  123..............................................................................................................LKARNMELHRDMKRLTAIFEKLHTYVSLLALPSTKFTNIAASLHGSHDILKDISKHYSQKATLEQDVPTATQKLVTTNDCILSSILSLTNGVGKIASFFSNNLDHFTSSLSYGPKGGTEFISPLSAECMLQYKKKAVAYMKSLKKPCADSVPYEEALANRRVLLSSTESREGLAQQ---------QQSLEKIAK-LEQEKEHWMLEAQLAKIKLEKENQKLKNSLSGHLAETVQERSSNTAEQKEETTEKSQREPIKTTSLIGMLTITTDNEKVPDVESREDLIKKHYMARIAELTSHLQLADSKSVHFHAECRALAKRLSLAEKSKESLTEELKLASQSISRLQDELMTTK---RSYEDQLSMMSDHLCSMNETLTKQREEIDTLKMTSK............................................................................................................................................................................................................................................................................... 515
13 -14.900PF05622.7; HOOK3_HUMAN/5-718; HOOK protein  ali follow..  11  198..............................................................................................................LDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANAARSQLETYKRQVVE----QNRLSEDKLDFEYKRLKEKVDSLQKEKDRLRTERDSLKETIEELRCVQAQQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLNQEGNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVKKLEEHLEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQEALRKKEEEMKQMEERYKK.............................................................................................................................................................................................................................................................................. 602
14 -14.600PF07902.6; Q1CPP5_STRPB/1-621; gp58-like protein  ali follow..  5  1............................................................................................................................MSRDPTLLIDESNLTIGSDGRAYYTFKADGDTKSVKLANNKCIGTTRFNQLMIERGGKPTNYVAPVVVEGSGESTGLFKNLEGALSQLKELNL--ELTDTVNSQLWAKIKLTTNGMLREYHRDNITTEIVESANGIATRISEDTDKKLALINETVSGIRRDY-----QDADRQLSSTYQAGINGLKATMANDKNDLKAVIQATAQGLSQKYDDEIQQLSAKITTTSSGTTEAYESKLADLRAEFTRSHQGMRTVLESRISGLQ-STQQSTAYQISQEIKNREGAVSRVQQDLASYQRRLQDTEKNYSSLTQTVRGLQSTVSAPNRGLESRVTQLAGLIEQKVTRGEMESYIRGAGDSIMLAIKGKLPQSKMSASEI................................................................................................................................................................................................................................................................................ 368
15 -14.600PF14073.1; CEP57_HUMAN/68-245; Centrosome localisation domain of Cep57  ali follow..  12  2.................................................................................................................................................................................................................................................................................................................IFSALKNLQDKIRRLELERIQAEESVKTL------------SRETIEYKKVLDEQIQERENSKNEESKHNQELTSQLL------AAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKRMQAKAAELQTGLETNRLIF................................................................................................................................................................................................................................................................................ 178
16 -14.600PF05667.6; CCD22_AEDAE/1-554; Protein of unknown function (DUF812 topsan)  ali follow..  9  210..............................................................................................................VPSLIAANDGAIKTNAKGAIDEVDRQVKLPAINEKLLQYYSKGGTKHRLAEPSGAAASSGTTEKVVLNNITVETKPGKTPLESLQEEIDALQQEIVQHSEEGVQLESSRKETDESIEEYRKTIVRLKEEKKIKERTHILLEDPEVNVKKLEAIIAAG----------------------------GERMKKLQDQWDAHRIPLVDTLEAYRLKNSDKLSKSQQVLDQ----------ESTRQKCEEVVIDLQTKGAMYARLQKEFEKLNKTVSRTAYTSRILEIIGNIRKQKNGIDQILQDTRSLQKEINNITGQLDDDLIFRNAKKDEHSKRAYKLLVTLHSDCEELIKLVQETGAIKREVRDLEDQIENEKGR............................................................................................................................................................................................................................................................................................... 553
17 -14.500PF07888.6; Q7ZTT2_DANRE/1-545; Calcium binding and coiled-coil domain (CALCOCO1) like  ali follow..  8  6...........................SVHF-RD--AVSTISSQHD------------------------------WSSRDWIGLFKVGWLTVKDYYTFAWALAPEGYQKGADANCSVAFHPSYLPIPGVEEYQFVYVDGRDVCAISSQFTFAAPRPLDELVTLEKSGEGEEDGDDLLLVVPKALILQNLLEGCQRELHELHKKFEAVNGDVE--NERQRWKTDRDEFEILRSDMRSQIEQLKTNLRHSTEKTEELERKHKEAQSSSESMSAEFNALLAERAENQQ-----KELEQDSLTQQKQDIEAELERMKERVKKMTIQRRDEETERIDLQLENEQ--MHADLRTLQERLEASERSTGALRRDLSELGSLQSHSHAELHQVRL--QSAQMSLQLSQANLALREGQSTWAQERETLRQSAELDKDRVQKLSRELQKKEEWLQEERSEREKLEVELGIEKDCNRELRASLRALQKEQEQHQLEKQELLDHIHVLELRLDT.............................................................................................................................................................................................................................................................................. 453
18 -14.400PF10168.4; Q707M9_XENLA/4-726; Nuclear pore component  ali follow..  9  402.........................................................................................................................FNRLEKFLSSGEEDKDSLQELAAEQKCLVEHILCTMPLRCRLPSPIQGFWIISDLFLGTSMICITCDFECIARPLLTTIRPPSPPLLCSQIDKSSTEILPHVLADVKGPFEIHIRGILRRNSANPLLLNSSSKDSSPPPEECLQLL------------------------SRATQVFREEYLLKQDLAKEEIQRRVKLLIAQKEKQLEDVRYC---------REERKSLTETAEHLAEKFEEAKERQEDLINRLKRILRSFHTQLP--VLSESERDMKKELQATTEQLQHLGNCINQVKRKMSYQEKQMEKGK----------SPRKSSLTLSDYQKKNIKTVLKEHGEHIQEMVKQINNIRNHVN............................................................................................................................................................................................................................................................................................. 722
19 -14.400PF05483.7; SYCP1_RAT/28-813; Synaptonemal complex protein 1 (SCP-1)  ali follow..  12  289................................................................................................................EKKDHLTSELEDIKMSMQRSMSTQKTLEEDLQIATKTIYQLTEEKEAQMEELNKAKTTHSLVVTELKAEELLRTEQQRLENNEDQLKLITMELQKKSSELEEMTKFKNNKEVELEELKTILAEDQKLLDEKKQVEKLAEELQGKEQELTFLLQTREKE---------------------HDLEVQVTKTSEEHYLKQVEEMKTELEKEKLKNIELTANSDMLLLENKK--LVQEASDMVLELKKHQEDIINCKKQEERMLKQIETLEEKEMNLRD--ELESVRKEFIQQGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKSKNIEELHQENKALKKKSSAENKQLNAYEIKVNKLELELASTKQKFEEMINNYQK.............................................................................................................................................................................................................................................................................. 661
20 -14.300PF04582.7; Q9DPB5_9REOV/1-326; Reovirus sigma C capsid protein  ali follow..  6  1.............................................................................................................................................................................................................................................................................................................MAGLNPLQRREVVSLILSLTSSTTTNPGDLTAV---------YERLTNLEASTKSLRQSLSSIVSDLSDVSVDLQDTTRALD------DAIATLKGLNTTVAALQNSVASLSSTVNGLTDISSAHSEALSFLRTTIDGNTVAISNLKGDVSTNGLNIADLQNRMKSLESSTSHGLSFSPPLSVADGVVSLDMDPYFCSQRV.............................................................................................................................................................................................................................................................................. 186
21 -14.200PF03999.7; PRC1_HUMAN/37-615; Microtubule associated protein (MAP65/ASE1 family)  ali follow..  9  1.........................................................................................................................LQRTEVVKKHIKELLDMIAEEESLKERLIKSISVCQKELNTLCSELHVEPFQEEGETTILQLEKDLRTQVELMRKQKKERKQELKLLQEQDQELCEIYDIDSASVPSLEELNQFRQHVTTLRETKASRREEFVSIKRQIILCMEALDHTPDTSFERDVVCEDEDAFCLSLENIAQKLLRQLEEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASD--PNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSK............................................................................................................................................................................................................................................................................................... 383
22 -14.000PF01576.14; O44934_LOLPE/1067-1925; Myosin tail  ali follow..  7  482................................................................................................................GALEQEEAKVMRATLEISQIRQEID--RRLQEKEEEFDNTRRNHQRAIESMQASLEAEAKGKAEALRIKKKLEGDINELEIALDATNRGKAELEKNVKKYQ--GQIRELQSQVEEEQAQRDEAKEHYQMAERRCAAINGELEELRTILEQAERARKAAENELADASDRVNELQA--------QVSTVGSQKRKLEGDVTAMQSDLDELNNELKDADERAKHAMADATR--LADELRQEQDHGLSVEKMRKSLESQVKELQVRLDESEAAALKGGKKMKLESRVRELEAELDSEQRRHAETQKSMRKVDRRVKELSFQQEEDRKNYERMQELVDKLQNKIKTYKRQVEEAEEIAAINLAKFRKVQQELEDAEERADQSEGALQKLRAKNRS.............................................................................................................................................................................................................................................................................. 859
23 -13.900PF10174.4; Q7Q0K7_ANOGA/59-838; RIM-binding protein of the cytomatrix active zone  ali follow..  9  318................................................................................................................ELEDKAKEDVDMIRERLDKCQTDLRRAQSEKDNQAEIERLTYELDRSHNLYTKQTASLDSAQEEIARYGLEIEKMRERYEKTAAELRRLQENESFSREARRMKDENDRLREKYDKVIVELENFRGKSQYEQETFDKMKEKFETRENEFQTMELKLHETSLQLDLARAEVTKLIS--------NQDKQRADAERAHIEYEKIRDKHEKLIKEVERLRQNPQSAISPGALAATSTVSLADKNELDRLRDRLEKALQSRDATEMEAGRLAKELEKQLHLTKQQEVYEATRIEFERMSAELTRVLERLEKSEAEKETLRQSTKIYE-KHHQQHASNHHIEQSLMKLEADNKQLMAERDQLVMQLEKSQDMLMSFQQELNAAEVELQRQCEENRRL............................................................................................................................................................................................................................................................................. 701
24 -13.800PF13304.1; B1HP30_LYSSC/55-363; AAA domain  ali follow..  10  2...........................AFIFGPNGSGKSNLFTALKVL---------------------------------------RTLLFNFENLNNVKQLRLPYQPFKLGSQQGQPTEFM---------------------------------------------------------------------------------------------------------------------------------------------------SLFLDGALYYEIQYNASIILYERLHKTTHNLKEELFVRRWDGVDYSYETAHSTAQELTKYTRN-NTAFISVLHVFNDSDALKVFDWFLHKMLFLDEANRLSSHPLIRKLEE----------EPFKKEVIKLLKIADFSIQDVT----------------------------------ARRVERREKNTIGYEFDSPEVIQEVDIDLHYLSFDESGVPIGNETINWTMD--------------------------------------SKGTVRMLHLACVMVDAYNKGK-----TIFIDEFDTAFHVSICEFLMAIMNS--------------------KRNTSNQFVVTSHEIELLD................................................................................................................................................. 309
25 -13.800PF08580.5; Q6FY01_CANGA/41-592; Yeast cortical protein KAR9  ali follow..  10  1................................................................................................................SSIEDLCDVLEWITTQMNRILEIFPQIIDSTGIEVSSLLEYLDWLQERKELLFELVNDINSIGPFLSDILEGIEANLNTDPNKSLDEHEMHLIDLIERCSTLRDDLDPWLNKLRKLLDATLEFKEISNDHMDGLDKVVSENIQSCFDIQEERFTSPVRHAPSFTLEQIVDLLKQ--------NSDSNAISVPTFNKQEKLISERFLELRRSVPAIEKSLTDILPNRIDNFARRDMTNIDSLAEFLRDKYKVLMKKYEFMSSEISELNAELIDKRWNILFVNLNHEINFILDDYEKLKKKLNS-VEEIGINVQIREKMSHQMTQKSLTIERTFKVIFKAQEFSLLD-AGIASKTNEMKNRWEKVRVDDKLLRSVSVDSGPEISSVTKDFES.............................................................................................................................................................................................................................................................................. 380
26 -13.800PF06160.7; EZRA_BACP2/3-562; Septation ring formation regulator, EzrA  ali follow..  9  97...................................................................................................................SKAKQVLTHIEDLLSAADSNI---EDILKEIADLVTSEEQNRKDIEKVKEQYQTVRKNLLAYSHLYGTLYDKMEQDLDEAWEGIKQYEEETENGNYMKARKILLEQDRRLDQLQLYINDVPKLIADCKQTVPGQLTKLKDGYQEMSEKGYKLEHIQITKELETLNKQLARAEKLLIDELNLEEASSILQMIDDAIETLYDQLEAEVEAGQEIKSRMPELTEEKLEQDHTQTKAETALVKESYKDQQKAFEKRLEEIEKLMKQIREKLDRHVAYSLLMDEINQLETFIEDAKALHDTFKGHLQSLRKEELQARETLAELKTMLTDTVRQLHKSNGVPAEMKERAEKAQEMIHQVHEQLENLPLNMPAVNQQLKEASDTVRNVVDETEEM............................................................................................................................................................................................................................................................................. 492
27 -13.700PF00261.15; Q805C4_TAKRU/12-248; Tropomyosin  ali follow..  16  25........................................................................................................................................................................................................................................................................................................DSERELREKAEGEVAALNRRIQLVEEELDRAQERLAVALQKLEE--AEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEDRKYEEVARKLVILEGELERAEERAELSECKASDLEEELKNVTNNLKSLEAQAEKYSEKEDKYEEEIKILTDKLKEAETRAEFAERTVTKLEKSIDDLEEKLSSAKEENLGMHQVLDQT............................................................................................................................................................................................................................................................................. 230
28 -13.400PF13558.1; A3YC50_9GAMM/971-1061; Putative exonuclease SbcCD, C subunit  ali follow..  13  33.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GSGGEKQSPFYVAIASSLALSNPGRSAGLALLDEAFDKLDEENLKNAMDFMGD........................................................................................................................................................................................ 90
29 -13.400PF05701.6; Q9FWW5_ARATH/24-519; Plant protein of unknown function (DUF827 topsan)  ali follow..  10  34................................................................................................................ESVCDKETQLMLVHKEFMKIKQKLDNAESTRSRLDDLSKAKKTMEDLSNKLETVNKSKQSAIDTKETVQQREEQLEHDKCHGSPPHHHELDVAREQYISTT--VELDAAKQQLNKIRQSFDSAMDFKATALNQAAEAQRALQVNSAKVNELSKEISD---MKDAIHQLKLAAAQ--------NLQEHANIVKEKDDLRECYRTAVEEAEKKLLVLRKEYEPELSRTLEAKLLETTSEIEVLREEMKKAHESEMNTVKIITNELNEATMRLQEADDECSLRSLVNSLRMELEDLRREREELQKEAERLEIEETKKLEALKQESLKLEQMKTEAIEARNEAANMNRKIESLKKETEAAMIAAEEAEKRLELVIREVEEAKSAEEKVREEMKMI............................................................................................................................................................................................................................................................................. 414
30 -13.400PF09730.4; Q3TBD4_MOUSE/9-723; Microtubule-associated protein Bicaudal-D  ali follow..  11  1......................................................................................GQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEIERQLEEALETLKTEREQKNNLRKELSHYMSINDSFYTSHLQVSLDGLKFSD----APPSPSLVSDLLSELHISEIQKLKQQLVQMEREKVGLLATLQDT---------QKQLEQARGTLSEQHEKVNRLTENLSALRRLQAGKERQTSLDNEKDRYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKISLLEKASHQDRELLAHLEKELKKVSDVAGETQGSLNVAQDELVTFSEELANL............................................................................................................................................................................................................................................................................. 457
31 -13.100PF03904.8; YP2A_STAAU/1-230; Domain of unknown function (DUF334 topsan)  ali follow..  7  2....................................................................................................................................................................................................................................................................................................................RKGQLIMSMKDIKNNKENPNTQMNSK----------------STGTPSSSTQNSLNNEELSELKRQNKLIVKYLA------EIQENQKIREKEQKEITSELKEATKDFRDKSLKIRNDFVDVLQEKLKHVDTEELKDILGRGIYKVREENDRMLQEVKRSHEHYQTRQKYLFTGIGAMLLVFMLFALIMTIGSDF............................................................................................................................................................................................................................................................................. 174
32 -13.100PF09074.5; RE107_YEAST/19-214; Mer2  ali follow..  8  2..........................................................................................................................................................................................................................................................................................................................EHSLMITETSSPFRSIFSHSGKVANAGALEESDKQILEWAGKLELESMELRENSDKLIKVLNENSKTLCKSLN--KFNQLLEQDAATNGNVKTLIKDLASQIENQLDKVSTAMLSKGDEKKTKSDSSYRQVLVEEISRYNSKITRHVTNKQHETEKSMRCTQEMLFNVGSQLEDVHKVLLSLSKDMHSL............................................................................................................................................................................................................................................................................. 188
33 -13.000PF08614.6; A16L1_PONAB/13-207; Autophagy protein 16 (ATG16)  ali follow..  6  3......................................................................................................................................................................................................................................................................................................................RHISEQLRRRDRLQRQAFEEIIL------------QYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTDSQLQEMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKLRKTTEENQELVTRWMA.............................................................................................................................................................................................................................................................................. 184
34 -13.000PF13555.1; Q0A6A1_ALHEH/19-80; P-loop containing region of AAA domain  ali follow..  22  8NWGTFHD---------RVWSLQPGGDNSLLTGDIGSGKSTLVDAITTLLVPAQRITYNKAAGA..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 61
35 -13.000PF07111.7; CCHCR_PANPA/27-782; Alpha helical coiled-coil rod protein (HCR)  ali follow..  11  331................................................................................................................DSVKQLKGQVASLQEKVTSQSQEQAILQSLQDKAAEVEVERMGAKGLQLELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEEAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLRQESCPLPPPVADVSLELQQLREERNRLD-LQLSARLIQQEVGR----QGEAERQQLSKVAQQLERELQQTQESLASLGLQLEVARQGQQESLTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAA-ERSQELRRLQEEARKEEGQRLARRLQELERDKNLMLATLQQEGLLSRYKQQRLCSASAPIAAAVPTRESIKGSLSVLLDDLQGLSEAISKEEAVCQGDNLDRCSSSNPQMS.............................................................................................................................................................................................................................................................................. 755
36 -12.900PF05276.9; Q4SIQ7_TETNG/16-252; SH3 domain-binding protein 5 (SH3BP5)  ali follow..  12  21........................................................................................................................................................................................................................................................................................................DDINRWESELEDGRQRFRAVLVEAMCKLDGLMKRIGRAVDDSKP--YWEARKVAKQAQIEAQKATQEFQRSVEILRAA-KETIALAEERLLEEDSRQFDSAWQEMLNHATQRVMEAEQSRTRSEAEHKKTAANYNSSISHMRQLEKKLKRSINKSRPYFELKGKYYLQLEHLKILVNERQAKLMSAKAEYRKALRNLESISEEIHA.............................................................................................................................................................................................................................................................................. 223
37 -12.900PF05335.8; Q8T4I3_DROME/75-260; Protein of unknown function (DUF745 topsan)  ali follow..  9  1..............................................................................................................................................................................................................................................................................................CGLSQKNAKSKASSIAIKAAQDAKAANDAQMAAGEAASLQVKQDLAEKA---------------VQAARAAEAALAGKQQIMEQLELEEKEAVAVVD------EVKNSLHSTQVNAESAMLAFSEAKIQLDQLKVLLAEATAQMTNIETFANGAQLEMDEKGQLLEAANRRVESISRQVVAARQDYDKTKKAAYKAACAAVEAKQKA....................................................................................................................................................................................................................................................................................... 186
38 -12.800PF04310.7; MUKB_ECOLI/1-227; MukB N-terminal  ali follow..  13  14NWNGFFA-----------RTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLT.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 56
39 -12.700PF09728.4; Q5RIN4_DANRE/94-406; Myosin-like coiled-coil protein  ali follow..  11  1..........................................................................................................................KGLGKEAASLLQSLNKLGSPEEKVEMVLKKYSELVDEHRTEKKQLEQFQQRQGLLVKQRDQLQFEHSRAILARSKLETLCRELQRHNRTLKE-ESLQRLREDEMKRKEITTHFQSTLVDIQSQIEQHSNRNNKLCKENSEL--------------------------------AGKLKTIIEQYERREESLEKIFKHRDLQQKLSDAKLEEA------------NMLLTQAEEKHKREKEYLLKEAIDKTKKYCTLREQEL------QMKKQLVLYSQKFDDFQNTLAKSNEIYVTFKQEMDKMTKKMKKLEKESTTWKTRFESCNKALVEMIDERSEKGKEFELFTLKIDRLETLCRALQDE............................................................................................................................................................................................................................................................................................... 312
40 -12.700PF05879.7; RD3H2_ARATH/46-791; Root hair defective 3 GTP-binding protein (RHD3)  ali follow..  9  1..............................MGPQSSGKSTLLNHLFKTSFREMDAFAGRSQ------TKGIWMARCVGIEPFTIAMDLE--EKQSALFAIAVADIVLINMWCHDIGREQAANKPLLKTVFQVMLRLFSPRKTTLLFVIRDKTKTPIELLERALREDIQKIWDSVRKPEAHKNTPLNEFFNVMIVALSSYEEKEKQFEQEVAELRQRFFHSISPGGLAGDRRGVVPASGFSFSSQQIWKVIKENRDLDPAHKVMVATVRCEEIANEKLRDLATNESW-----GKKLSSILEKYFSEYDAEAIYFDEGVRKEKRLLDFVYPSYATMLGHLRSNALESFKIRLEQSLNQGEGFAKAVRDSQQSCLMVFDKGCEDAAVKQATWDASKIREKLCRDIDAHTFFARSLSELTANYEKRLTQALSEPVESLFEAGGKETWPSIRKLLKRETETAVTDFLDVVTGFELDHAKIDAMVQNLKNYSQSLVE--KKAREEAAKILIRMKDRFSTVFSHDKDSMPRVWTGKEDIRAITKDARAEALSLLSVMTAIRLDERPDN-----IESTLFSLTPVQCKSLWRQFKSETEYTVTQAISAQEAHKRNNNWL----MIVLGFN-EFMMLLKN............................................................................................................................................. 661
41 -12.600PF11172.3; A6B5A0_VIBPA/11-211; Protein of unknown function (DUF2959 topsan)  ali follow..  11  16...................................................................................................................................................................................................................................................................................................EQVGYHKRDIMVDRVEDAKESQQEAQEEFTSALEALSALTNFDGGELESV-----YNNINDKYEDSEKAAQDVRDRIAAIEDVSDALFEEWQGELDLYTSAKLRRSSEQKLRETKASYKTMLSAMKRAEKKMTPVLNTLRTLYLKHNLNASAIGSLQGEFSSLEKDIQFAIKQMNEAIAESDKFLQKLN.................................................................................................................................................................................................................................................................................................... 201
42 -12.400PF04849.8; Q4SVU4_TETNG/101-401; HAP1 N-terminal conserved region  ali follow..  11  88........................................................................................................................................................................................................................................................................................................KALSERNDLLEEQVEHIREEVSQLRHDLSMKDELLQFYTNAAEEFTSTPVRPADSNVSTPTFFPLDSLQKKLKDLEEENKSLRSEASHLET--ETISYEEKEQQLVHDCVKELRNSNLQITSLSEELARKSDDASRQQEEITHLLSQIVDLQKKVKLHALENEELTQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNL............................................................................................................................................................................................................................................................................. 297
43 -12.400PF05010.9; Q2NKK4_HUMAN/638-837; Transforming acidic coiled-coil-containing protein (TACC)  ali follow..  5  1...........................................................................................................................................................................................................................................................................................................QYSQKDLDAVVKATQEENRELRSRCEELHGKNLEL-----GKIMDRFEEVVYQAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSEKSFSDLFKRFEKQKEVIEGYRKNEESLKKCVEDYLARITQEGQRYQALKAHEEKLQLANEEIAQVRSKAQAEALALQASLRKEQMRIQSLEKTVEQKTKENEELTRICDDLISKMEK.............................................................................................................................................................................................................................................................................. 200
44 -12.400PF05911.6; Q10P54_ORYSJ/79-939; Plant protein of unknown function (DUF869 topsan)  ali follow..  9  473.....................................................................................................QSRISSLLDSESPQNNAGNILDSIRNILKDIEDEADSSNDSKTHHGDMVEVADNGSLMKHSSSGSKHAMDQ-------------ELVNAILKIQDFVKSLDQEVSKFQGQSSDCDGLCDKIQQFSALVEKALSNENVLNDIVMTLSLILSGTSEIKFMMLKENTKEADNNNLDYVDKVTLLENKV-----------QLEPLKDSISGPCLPRSSSDPEIEGPTDSGCDVKTAVQICSSEEF-----EQLKSEKLNLEAELSKCNEVIEETKFRFKELEKSLE------ELTSKLVASEKSNSLAETQLKCMAESYKSLESRKAELENEIKVLQSKIEVLTAELDDERQNHQEDITRYRDLEEKIERYENERNSMEKEIAAAAEKLAECQETILILGRQLQSM............................................................................................................................................................................................................................................................................. 851
45 -12.300PF14362.1; D3CY45_9ACTO/50-394; Domain of unknown function (DUF4407 topsan)  ali follow..  12  96................................................................................................................................................................................................................................................................................................VISTPLVLRIFEAEITTELSLMRSERDSEFLATTQTDERGMRIKAL-EAEQKTLQATIDTSTDTVDVSTDPDVARIQKLVDTKQQQYDAAEQAVICENEGTC-GSGKVGRGPAYAEKVALRDRYRDELSVLNGQLTTAQATAR---------SKATDTRGAAQNTAKGRLKTVETELTDLRTARTAAIANFRKENGKENGLLIRIEALDN-------------------------------------LTAHRPALGLAHRFLLVF----------ITAIE-PIGPAN..................................................................................................................................................................................................... 333
46 -12.100PF12795.2; Q3KJ67_PSEPF/35-273; Mechanosensitive ion channel porin domain  ali follow..  9  2..................................................................................................................................................................................................................................................................................................................SLDKLTDSKLPEADKKALQTVLQNTLNQLNNRRD--YEQKLIDLKQQLATAPKQTIENSRELTRLKASAVVPVAQRFPKENIQQLEQMLTERSTQQSDLQKALADANSLIITAQTRPERAQAEISSSQTRIQQINNILKTSAEQRDLLNAELAALNALIPLRRQELAGNNQLQDLGNSQHDLLSEKSDRLDREIQEL............................................................................................................................................................................................................................................................................. 204
47 -11.900PF13851.1; GAS8_HUMAN/220-420; Growth-arrest specific micro-tubule binding  ali follow..  11  1...........................................................................................................................................................................................................................................................................................................HTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERD---KQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEDVLESKNSTIKDL................................................................................................................................................................................................................................................................................ 201
48 -11.900PF04163.7; KAR5_SCHPO/1-544; Tht1-like nuclear fusion protein  ali follow..  9  136.....................................................................................................................................................................................................................................................................................SHFHDVNHLCRLANLEMQKELSIEVNMNVTLVQKQFLEMVILHLRNFESVTDKMNQRIDKFDGKF----NSVIENSFKDINFRVNQEIMGLVELQNHQQEGMVQQKEILS--TIKQLKSEIFDINSFFANFIEESAGYSNSLIEKLNEKFTSENAIALSAIGKYTSEFSAFMEKRIKNLITTTEDSLQQSVQSNIDFVNSGFQPLYDLTIQLKEELQSLKRLSSEQQNLQHEQILQWKSDFLNVSKDHLKVLQQLRPLIDIVEKFMNVYFKGLSNIISS........................................................................................................................................................................................................................ 408
49 -11.900PF06818.10; Q4RYH9_TETNG/478-682; Fez1  ali follow..  5  2..................................................................................................................................................................................................................................................................................................................KWEVCQKSGEISLLKQQLKEVQGELAQRVGEIVS---RGQLRETRGELTNTQVLLQEAHGTTRTRTLELEVCENELQRKSEAELLREKAGRLEAELAHLKDALASQGPGNRQCQVFPEDQEQLLARAQEPSQNMSVKMDRMRAELSYEHQRAEQQMSSFEEERRIWQEEKDKVIRYQKQLQQNYVQMYRRNRELEQ.............................................................................................................................................................................................................................................................................. 201
50 -11.800PF13870.1; B4J5C0_DROGR/499-675; Domain of unknown function (DUF4201 topsan)  ali follow..  9  2...............................................................................................................................................................................................................................................................................................................SQKRNEISDDRLYLISRKHTLGRITDKITKL-EQINEDLCMDDFINIQNQVAALDKKIEERNNDLKKLRLNYHTELHLTQHREKALALDSKLDVAKLNLEIMQKKQDQLRECLYKAKLERSNIRKVHS--DLSFQGGLLSMPALMFDYDETVERVRAKQASVKELKETFKHITQRILE................................................................................................................................................................................................................................................................................................... 177
51 -11.700PF10481.4; CENPF_HUMAN/1-288; Cenp-F N-terminal domain  ali follow..  15  5......................................................................................................................................................................................................................................................................................................LEEWKEGLPTRALQKIQELEGQLDKLKKEKQQRQFQLDSL---------EAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKTKQ------KISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQA..................................................................................................................................................................................................................................................................................... 190
52 -11.700PF04111.7; YDKA_SCHPO/121-497; Autophagy protein Apg6  ali follow..  13  3.....................................................................................................................................................................................................................................................................................................................................EIYNRIFDLLSSKTKVDHPLCVECAELLTEEMSKTLRALKEEKKMYFNYDNFLSSQTVHEENTAALDSEIDELMKQINEKEEKIEEISDETDKLQKLLRELDEEKEKVYAEEQEFYNNLNQFQIKKLSLERQYDCANLEFEHNSRKLEKLQKM...................................................................................................................................................................................................................................................................................................... 155
53 -11.700PF10473.4; Q9GKN4_CANFA/3-142; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1  ali follow..  10  2..............................................................................................................................................................................................................................................................................................................................................................EKKQLHVLEKLRESERKADALQDKIENLERELQ------MSEENQELVILDAENSKAEVETLKTQMELTTKSLKDLESDLVTVRFEKENLIKQLQDKQGQVSELDTLLSSFKGQLEEKEREKIEMKEESRAALEMLRTQLKELNE..................................................................................................................................................................................................................................................................................... 140
54 -11.600PF13476.1; C4P4D4_ARATH/25-232; AAA domain  ali follow..  11  6NFMCHSNLE-----------IEFGDWVNFITGQNGSGKSAILTALCVAFGCRARGTQRAATLK------DFIKTGCSYALVYVELKNQEIYGDTLIIERRISDSTSLTVLKDHQGRKISSRKEELRELVEHYNIDVENPCVIMSQDKSREFLHSGNDKDKFKFFYKATLLQQVDDILQSIGTKLNSANALLDEMEKTIKPIEKEINELLEKIK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 208
55 -11.600PF10234.4; A7SE98_NEMVE/14-284; Clusterin-associated protein-1  ali follow..  12  64...........................................................................................................................................................................................................................................................................................................AHIKLNTKKLYGADGYAVKELLKVTSVLYNAMKS-----NVTDDEAEPSDVTSLTFDISSRISDLKASRQLASEITTRGAALYDLLGHEVELRDIRTRAIAKPLEVNELENGIKKSISLAQDDIRKTTQMLDNIASDEANLEAKIDKKKQELERNQKRLRSLESVRPAFMDEYEKLEEELKKVYETYMEKHRNLSYMEQLLDD.............................................................................................................................................................................................................................................................................. 261
56 -11.600PF06637.6; PLVAP_HUMAN/1-442; PV-1 protein (PLVAP)  ali follow..  10  11..............................YARAGGSRG-FVSLIQFL-----------------------------------LVLFMVYGNVHVSTESNLQATERRAEGLYSQLLGLTASQSNLTKELNFTTRAKDAIMQMWLNARRDLDRINASFRQCQGDRVIYTNNQRYMAAIILSEKQCRDQFKDMNKSCDALLFMLNQKVKTLEV-EIAKEKTICTKDKESVLLNKRVAEEQLVECVKTRELQHQERQLAKEQLQKVQALCLPLDKDKFEMDLRNLWRDS-----PRSLDNLGYNLYHPLGSELASIRRACDHMPSLMSSKVEELARSLRADIERVARE-NSDLQRQKLEAQQGLRASQEAKQKVEKEAQAREAKLQASRQTQLALEEKAVLRKERDNLAKELEEKKREAEQLRMELAIRNSALDTCIKTKSQPMMPVSRPMGPVPNPQPIDPASLEEFKRKILESQRPPAGIPVAPSS............................................................................................................................................................................................................................................................................................... 441
57 -11.600PF10498.4; IFT57_XENTR/25-384; Intra-flagellar transport protein 57  ali follow..  9  153........................................................................................................................................................................................................................................................................................................EEDSDNDQEHFIDLNALSAQTQKLNTKESSKPEEILES-NTDAAEWILEVERVLPQLKVTIRTDNKDWRVHVDQMHQHRDGIDTSLKETKG--YLDKLHNEVAKALEKVSSREKYINNQLEQLVQEYRSVQAQLSEAKERYQQASGGVTERTRILAEITEELEKVKQEMEEKGSSMTKIKQALTKLKHEIVQMDIRTGVVEHTL................................................................................................................................................................................................................................................................................ 359
58 -11.500PF12532.3; B3QEB7_RHOPT/422-613; Protein of unknown function (DUF3732 topsan)  ali follow..  10  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................ELISKLESEIEDLTVPPIN-----ERQELFTSALDEAIQDYISLTRDALGNYGNYSEKKLHLRKPRTASTENVGSSSNHMFLHLFLFLGIHERNNGIHVAPFLIIDQFSRPYDVAKVKLALELLNQFITTANTIGKD---------------QIIVFEH....................................................................................................................................................... 167
59 -11.500PF12240.3; B1AXE8_MOUSE/396-605; Angiomotin C terminal  ali follow..  11  1.....................................................................................................................................................................................................................................................................................................................YVDKVEKMQQALVQLQAACEKREQLEHRLRTRLERELESLRIQQRQGNSQPTNASEYNAAALMELLREKEERIL------ALEADMTKWEQKYLEENVMRHFALDAAATVAAQRDTTVISHSPNTSYDTALEARIQKEEEEILMANKRCLDMEGRIKTLHAQIIEKDAMIKVLQQRSRKEPSKTEQLSSM................................................................................................................................................................................................................................................................................. 184
60 -11.500PF06409.6; A6NCT9_HUMAN/1-331; Nuclear pore complex interacting protein (NPIP)  ali follow..  9  3..............................................................................................................................................................................................................................................................................................C--C---VINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFT------LWRQVETKVRAKICKMKVTTKVNRH--DKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARK........................................................................................................................................................................................................................................................................................... 209
61 -11.500PF11180.3; B2JKS0_BURP8/32-221; Protein of unknown function (DUF2968 topsan)  ali follow..  13  82.....................................................................................................................................................................................................................................................................................................................................................................................................QDEARAEQIYRDFARQTVQLSDVEIRRAKLEAQKAYTDRLVALSQERASRLQADLNIAHEQQTIVNSLQQQTRAEAAALAQQKAQSQEQLRATQRQVRDLQRQLES..................................................................................................................................................................................................................................................................................... 187
62 -11.400PF09738.4; LRRF2_BOVIN/31-326; Double stranded RNA binding protein (DUF2051 topsan)  ali follow..  12  59........................................................................................................................................................................................................................................................................................................GNSSRRVSGDTSSLIDPDTSLSELRESLSEVEEKYKKAMVSNAQ--LDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERKHMCSVLQHKMDELKEGLRQRDELIEKHGLVIIPDGTPNGDVHQEPAVGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSGRDGTAGDLAELQNG.............................................................................................................................................................................................................................................................................. 263
63 -11.300PF10368.4; YKYA_BACSU/16-219; Putative cell-wall binding lipoprotein  ali follow..  9  11.................................................................................................................................................................................................................................................................................................CMGQDPVDSLHHSLEKAAESEKPFQEEQNTLKELEAKENQLYDSVMKLNMDD-----YKKIVALSNKALENVSKREEHLKLENDSMKKSETEFEEAKTSAE-HIKEKDIKEKADAAANHMEKRYTSYGTMYKEYKKALELNKKLYMQLKDKDLTRDDLDQQIDKVNASYEKILKYSGEFNEQTEKYNKAREDLYDAAGY............................................................................................................................................................................................................................................................................................ 203
64 -11.100PF09789.4; Q16UI1_AEDAE/24-343; Uncharacterized coiled-coil protein (DUF2353 topsan)  ali follow..  8  1......................................................................................................................HRKLQSKVEALKIMRNELEKYRSERDQFKLMAETLQMRYSAMKSSLNSPEFQAAGFGHSSAVSLLVNQTRERNISLSTEVEALRQRVHELEGDIDVLRTKNFDLQAAFNKMKSTEETKLRDRKGIVW-------------------------------------------------------------DEEKSKLIAQMETLKKKNAQLQYDVRSL---------LDEKEDVVMERDAYKCKAHRLNHELSVMLKGDQSQQKIVDVDGENKYQQEKITNLENELELSRQSATKYKNMLDTKRKKGIIKLGTNNNQRVMSHSQVKDLRGTVEELPLKAATISELKSLCLALLDNVNDKSLALSHQKKTNKLLAAKITELEQRILAL............................................................................................................................................................................................................................................................................. 320
65 -11.100PF03148.9; A7SG13_NEMVE/17-399; Tektin family  ali follow..  7  10................................................................................................................TNAERQREASHRVRQESRFLRNETDNHWTQHDSNTKLEKRIDDINDWKRSLERCLAETDNEIALLTREK---ERTERALEAKKVPLDITLECLMLRENRQSIDLVRDEVEAQLHKEVEVIEGTKALLQQKVDESFEQLCLLQEARHQLHLDITDKFTT----------------------QIDGDCYAMNNMSTNIGYQVNPTRTVKGSVTPETWDSFSNYNKLRAEAEM-KASKHLREAIFATLQQTANDLEAQRKASEYSFRKRIHETDQAKS--ELEWQQKNTMKEIATLEDDIKGLKEAIDAKNAPMMVAQTRLENRTYRELCRDQPQYQLCHEVAEIAGSMRALTEKLREAQNSLEALRSNLSRINEDLAFKNNSLA...................................................................................................................................................................................................................................................................................... 369
66 -11.100PF03429.8; Q9RQF5_ANAMA/1-720; Major surface protein 1B  ali follow..  8  161...............................GMHAEGQAQISQGIADKSTALVREGLETSR-----LGAGLCRNGLVEASYGVSYANKTMGK-------------KGLEKCKNKLDDACHKWHDALNEIESLRTAIDAKAEQQVEGEAWSPEGVSANTFYRGLHKIGAAIAVAAQATWEGLAMTGKFMGAVAKLAGAVSMCVAAYTAAIAGILPAGIPLAFMGPESKLAEYVDRAASYLHSNVEQATKDLMASEFAMMTFGGIMTCAKLMKGSFAAVN------------------QKFEEINATLAREGTDIAQGIKETYKSIGDAFKSVNTGIAKWTTDKWTAALAGYASVEQLEEAKADRAQAEQRAEAQAMTERVAQ---------------ERAATVAAGTETIKTIVSDMCNELAQICGLSQA-ERDALVQSFIPQPPRTTKEIVSQMCNSVKSAFGSISHITNVIRQAGKDAQKIDPQVKVAEISPETIYAMSEALYALNMQESAAINNALLEAVNDSSKDDDLINATIEVCTEQTNTLAGHTAEVQAGLEAAGIKL----KGVEGINPEELAQAAEGLATAVNEASAEGKIQSLNQQESQIQHAAQQ............................................................................................................................................................. 713
67 -11.000PF05384.6; A4J6C1_DESRM/9-167; Sensor protein DegS  ali follow..  9  1..........................................................................................................................................................................................................................................................................................................................................................DNIIKETISVIEKSKEQIYYIAESAHLEWQRVENEIK------QTKYQLGKIIDEVNKLEIEERRARVRLMEVSRDFDRYEAAIKQAYEQAQVTQLRLVMLREEEKTLRFKRDHLEISLKRMKDTADRAEKLVSQVGVALQYLSKDLSGVSEKLTNL............................................................................................................................................................................................................................................................................. 152
68 -11.000PF05478.6; Q7Q6R9_ANOGA/26-846; Prominin  ali follow..  9  156......................................................................................................................................................................................................................................................................FVTNSYMQHGVENITTSARHGVHDTRLYLQTTSAHIDHVLNKNYQELNNDLKQLLHDASDNIIKRLEEESKAEKLTTLYEFVEKLPGIKGSLEKMKQLTSELRITASQLNDGLRGVKRELLTSLNKCGTQECIKVMDDYKIGRLNVNGIDYNSLPDLSQIIESVKQLTD------SSLGSAIHQGVDQMNELKSTLRQVLQNIPKVQAASDSTGKAIKDVSNMLTSLNNVADTLGNNSYKHLDTADEYIEQYSIKRPDGYGDDCCNKGAGGRFLIFS---AVALASFLV----RDPANDQIINYLDQFVKVLKLNNFIDIRTIRD------FPEHYGITRELAALKEKIKIQSVQILTPEAT--EDIRALQESKLNDFDVDKFTDNLTFNITEYN--LNEIADKLREVANRVPSGKEMNDIKVNLKN---QALHLSSYQTNLVDPMIASTNELIKLSTTLDTSLKFGEKSFSAAIDKFLTQIKDAEEYINKYGKTFVQNVTEELVSGFNN 740
69 -11.000PF03082.9; MS2A_DROME/1-264; Male accessory gland secretory protein  ali follow..  8  64........................................................................................................................................................................................................................................................................................................KDAKKGDYIMDIDISDLPLDDYPINRSKSLKSSSIDLN---------NIPFNKGLDDFPAKEKNQGSNQSALKALQQRLLTEQNNSL------LLRNHSIYLMKEIEARKTDIIKVRQLNLDLELELNTVNRRLLELNGQLQNTRKSTKPCKKRAPPAANQFQEANVRNTYRNKYLTLLKELSQKINNEIAKVATDVPTETNPSQG.............................................................................................................................................................................................................................................................................. 259
70 -11.000PF08702.5; FIBG_HUMAN/29-173; Fibrinogen alpha/beta chain family  ali follow..  16  22...............................................................................................................................................................................................................................................................................................................................................................GIADFLSTYQTKVDKDLQSLEDILHQVEN---------KTSEVKQLIKAIQLTYNPDESSKPNMIDAATLKSRKMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHD................................................................................................................................................................................................................................................................................................ 145
71 -11.000PF08317.6; Q754X4_ASHGO/431-759; Spc7 kinetochore protein  ali follow..  11  67...............................................................................................................................................................................................................................................................................................................EIYAFIVKELHRRILDSQRLFQELEEQISNNPPPYLFRNYFESSDEVKQLMKEQIVLIKSFAR-LEAKKVWFEWRCQHLKGIKS--VLEENLSLVQTEYAEVVARLNEISDIKHRLQALEQSLRHELELLRNGEKPMRVTTLADRLKIEKIKSELKANMNNTANLEEQKEAISADINALRSQIKDVREEISSLKSLVLK.............................................................................................................................................................................................................................................................................. 265
72 -10.900PF08172.7; CASP_SCHPO/399-628; CASP C terminal  ali follow..  11  2...........................................................................................................................................................................................................................................................................................................................................................TQESKKASFLEQKASEQEEVIRKLEKDLADVDVEGSVYLSREGTSGQLSPTSSIMGGNPSLFNGSVLSRNSVNETGSAIVDVIKQ---QRDRFRRANVTLVNQVSAANDKIALLESKLEEVEKSNTLLYEQMRFRDHYQKHVEPSSSHLQTA------------AAYENSISPFASFRKKEAERAYSRMGSFERIVYALLRTLLF............................................................................................................................................................................................................................ 196
73 -10.800PF09755.4; A0AUQ3_DANRE/3-319; Uncharacterized conserved protein H4 (DUF2046 topsan)  ali follow..  9  1..........................................................................................................................ADSASESDTDGATPHCSSSSSSSILISSFRLEELSNRLASLQQENKVLKIELETFKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEK------------------------------------------AELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQL-RREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPP------SPRDTISMEIDSPENMMRHIRFLKSEVERLKKNLRTSELQHTE---KRAQYIEEERHMREENIRLQRKLQREVERREALCRQLSESESSLEMDDERYFN............................................................................................................................................................................................................................................................................................ 314
74 -10.700PF07246.6; Q88304_SFSV/4-294; Phlebovirus nonstructural protein NS-M  ali follow..  8  68........................................................................................................................................................................................................................................................................................................DFKYMTHENAMKQIKIVTTAPDTMKFSCGDETKSLGLSITNDGTNNMAIIYCDTNDFIRNITTGEQSPRVDYEKLKKNAEEKDATIQRKTK--EMEEVRAVLDSRNQIAHHEIQQKENEIQKLRNDLRDAIKKGQ----EHESMKLRVEESDARVKGLKEELKQLTYKIFDHQATKDELQHAKSEMQSLRKKIKDFESIPQAKKSSN............................................................................................................................................................................................................................................................................. 271
75 -10.700PF06008.9; P70570_RAT/237-496; Laminin Domain I  ali follow..  14  23...................................................................................................................................................................................................................................................................................................KDLRNQLFRSAISSHGSQMDGLEKELSHLYQEFETLQEKAQVNSRKAQT--LYNNIDTTIQNAKELDMKIKNILTNVHILLKQIARMLRELRGRDFKKHLQEAEAQKMEAQLLLNRIRTWLESHQVENNGLLKNIRDSLNDYEAKLQDLRSVLQEAAAQGKQATGLNHENEGVLGAIQRQMKEMDSLKKYLTEHLATADASLLQTNSLLQRM............................................................................................................................................................................................................................................................................. 256
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alonso A, Rahmouni S, Williams S, van Stipdonk M, Jaroszewski L, Godzik A, Abraham RT, Schoenberger SP, Mustelin T. Tyrosine phosphorylation of VHR phosphatase by ZAP-70. Nat Immunol. 2003 Jan;4(1):44-8. Epub 2002 Nov 25.