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Query: PF02399.13; OBP_VZVD/13-828; Origin of replication binding protein, from PfamA30U

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst YASSTQLARALYGGDLVSWIKHTHPGISLELQLDVPVKLIKPGMSQTRPVTVVRAPMGSGKTTALLEWLQHALKADISVLVVSCRRSFTQTLIQRFNDAGLSGFVTYLTSETYIMGFKRLIVQLESLHRVSSEAIDSYDVLILDEVMSVIGQLYSPTMRRLSAVDSLLYRLLNRCSQIIAMDATVNSQFIDLISGLRGDENIHTIVCTYAGVGFSGRTCTILRDMGIDTLVRVIKRSPEHEDVRTIHQLRGTFFDELALRLQCGHNICIFSSTLSFSELVAQFCAIFTDSILILNSTRPLCNVNEWKHFRVLVYTTVVTVGLSFDMAHFHSMFAYIKPMSYGPDMVSVYQSLGRVRLLLLNEVLMYVDGSRTRCGPLFSPMLLNFTIANKFQWFPTHTQITNKLCCAFRQRCANAFTRSNTHLFSRFKYKHLFERCSLWSLADSINILQTLLASNQILVVLDGMGPITDVSPVQFCAFIHDLRHSANAVASCMRSLRQDNDSCLTDFGPSGFMADNITAFMEKYLMESINTEEQIKVFKALACPIEQPRLVNTAILGACIRIPEALEAFDVFQKIYTHYASGWFPVLDKTGEFSIATITTAPNLTTHWELFRRCAYIAKTLKWNPSTEGCVTQVLDTDINTLFNQHGDSLAQLIFEVMRCNVTDAKIILNRPVWRTTGFLDGCHNQCFRPIPTKHEYNIALFRLIWEQLFGARVTKSTQTFPGSTRVKNLKKKDLETLLDSINVDRSACRTYRQLYNLLMSQRHSFSQQRYKITAPAWARHVYFQAHQMHLAPHAEAMLQLALSELSPGSWPRINGLast
1 -228.000PF02399.13; OBP_VZVD/13-828; Origin of replication binding protein  ali  100  1YASSTQLARALYGGDLVSWIKHTHPGISLELQLDVPVKLIKPGMSQTRPVTVVRAPMGSGKTTALLEWLQHALKADISVLVVSCRRSFTQTLIQRFNDAGLSGFVTYLTSETYIMGFKRLIVQLESLHRVSSEAIDSYDVLILDEVMSVIGQLYSPTMRRLSAVDSLLYRLLNRCSQIIAMDATVNSQFIDLISGLRGDENIHTIVCTYAGVGFSGRTCTILRDMGIDTLVRVIKRSPEHEDVRTIHQLRGTFFDELALRLQCGHNICIFSSTLSFSELVAQFCAIFTDSILILNSTRPLCNVNEWKHFRVLVYTTVVTVGLSFDMAHFHSMFAYIKPMSYGPDMVSVYQSLGRVRLLLLNEVLMYVDGSRTRCGPLFSPMLLNFTIANKFQWFPTHTQITNKLCCAFRQRCANAFTRSNTHLFSRFKYKHLFERCSLWSLADSINILQTLLASNQILVVLDGMGPITDVSPVQFCAFIHDLRHSANAVASCMRSLRQDNDSCLTDFGPSGFMADNITAFMEKYLMESINTEEQIKVFKALACPIEQPRLVNTAILGACIRIPEALEAFDVFQKIYTHYASGWFPVLDKTGEFSIATITTAPNLTTHWELFRRCAYIAKTLKWNPSTEGCVTQVLDTDINTLFNQHGDSLAQLIFEVMRCNVTDAKIILNRPVWRTTGFLDGCHNQCFRPIPTKHEYNIALFRLIWEQLFGARVTKSTQTFPGSTRVKNLKKKDLETLLDSINVDRSACRTYRQLYNLLMSQRHSFSQQRYKITAPAWARHVYFQAHQMHLAPHAEAMLQLALSELSPGSWPRING 816
2 -18.100PF07652.12; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  14  2.............................................KKKQLIVLDPHPGAGKTRKVPEFIRQAVERRLWTLALAPTRVVAAEMAEALNGLPVRYLTPAVIQQH--TGKEIVDLMCHATF-LSGGRVPNYNMFIMDEA-----HFTDPSSIAARGYISTKVD--MGEASAVFMTATPPGSREPFPDS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 146
3 -15.500PF01443.16; RDRP_TMV/829-1085; Viral (Superfamily 1) RNA helicase  ali follow..  11  1..................................................VLVDGVPGCGKTKEILSRV-----NFDEDLILVPGKQAAEMIRRRANSSGIIVATKDN------------VKTVDSMMNFGKSTRCQFKRLFIDEGLML-----------HTGCVNFLVAMSLCEIAYVYGD---------------------------------------------TQQIPYINRVSGFPYPAHFAKLEVDEVETRRTTLRCPADVTHYLNRRYEGFVMSTSSVKKSVSQEMVGGAAVINPISKPLHGKILTFTQSDKEALEVQGETYSDVSLVRLTPTPVSDSPHVLVALSRHTC........................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 251
4 -13.000PF04851.13; Q893B7_CLOTE/244-395; Type III restriction enzyme, res subunit  ali follow..  14  15.......................................LERLRENGQDRGLLISATGTGKTYLSAFELRNY--NPKRALFIVHREQIAKQALNSFMNFGDTRSMGILSGTSKDVDKDFIFCTIQTLSKLQYFDKNEFDYIIIDEVHKAGANSYQKIVNY-------------NPKFLLGMTAT........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 149
5 -12.400PF01637.16; A8M939_CALMQ/15-228; ATPase domain predominantly from Archaea  ali follow..  16  4...............................REVAIRQIEKLAEKGTWNPVVIYGPEGCGKSAFLKQAVEVLGEYDYSVVKVSPLEDESNEKLRYSEERGLFRDIMTRIPTPFNDASALIDIAISLLYDVVRRRIRRKIALLADDVFQAIG--LDKAELLVKRLLNMIEYSSVDYERIVVIVATSEGVTWGRIGR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 166
6 -11.800PF05894.10; B3VMQ2_BPPH2/1-331; Podovirus DNA encapsidation protein (Gp16)  ali follow..  9.......................................PQKMLSYDRILNFVIGARGIGKSYAMKVPINRFIKYGEQFIYVRRYKPELAKVSNYFNDVAQEFPDHELVVKGRRFYIDGWAIPLSVWQSEKSNAYPNVSTIVFDEFIREKDNSN--IPNEVSALLNLMDTVFRNRERVCICLSNAVSVVNPYFLFFNVYDDALIEIPDSLDFSSERRKTRFGRLIDGTEYGEMSLDNQFIGDSQVFIEKRSKDSKFVFSIVYNGFTLGVWVDVNQGLMYIDTAHDPSTKNVYTLTTDDLNENMMLITNYKNNYHLRKL-------ASAFMNGYLRFDNQVIRNIAYELFRKMR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 330
7 -11.500PF13401.4; B2UJB3_RALPJ/42-210; AAA domain  ali follow..  17  1............................................DSQESILLVCGPTGAGKTTLAKFMVENAHSQSHAAIYVQ--RLFYQRILNQLGDDLDSPKVAYGVDSLSGRLVRPRGTSGNSLAALRTAVERQVQFMVIDEAAHIFRDTQRN--SKLEVQLDTLKSLVNECGTQIVLVGSYDLYHL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 168
8 -10.600PF13604.4; Q3L956_RHOE4/579-769; AAA domain  ali follow..  16  6...................................QIAMIEHFLTAKTKVAVAVGAAGAGKTTAAKVVARAWEQTNGKVIALGPSAKAADVLGAEIDV-----------------EGRTIADILTRDQHGLATGIEKGDLLLVDEAGMASARNLADLTRIATQSGAVVR-LLGDPLQLASVES......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 135
9 -10.400PF07088.9; GVPD1_HALSA/23-536; GvpD gas vesicle protein  ali follow..  15  8.............................................DAGETLLINGAPGTGKTLFTIRGL-DVLDRDSDVLYVSTRVTVHEMYFSSLDTTAILDLFQDPFELPLDVDVPFEKLDLDSLLEWIQEINAATTTIAFDSWELIYEYLRHDDPPDIKTVTNQLAVLAREENRLMLVTETAAPSSLEYIVD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 167
10 -10.300PF06745.11; O29463_ARCFU/20-274; KaiC  ali follow..  13  31..............................................HLAVMNITGVPDTGKSLLAEQFAITQAGSGYRVLYVTPANFLYTAMKERSEAMGVDFTKVESNVV-DASESDELRENPKALMETMAYAIKEKTNTIIDS----ITGLYEHKEMMARQIVRQFFNFMKKYRQTGIFVSQKRSAQASESAEAAGGLAVAHIVD................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 193
11 -10.200PF04665.10; Q6TUP8_YMTV5/6-246; Poxvirus A32 protein  ali follow..  12  1...................................EKHFYRKSLLKHPFRIALVGGSGSGKTAYLLSLFNTFVEKYRHIFLFTPVYN--SEYDSYIWPDHVNRVTTYEELDYSLITTKQKI---KYVKKQGNDKTTEMFLLILDDM------------GDKQIRSSCLLDFLNHGRHLNTSIILLCQTYKHVPVNGRTSITHFCCCNV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 157
12 -9.510PF13872.4; E4XRW5_OIKDI/32-343; P-loop containing NTP hydrolase pore-1  ali follow..  12  58.............................................GERKGFLLGDGAGVGKGRSISGIIYDNWLNGKKAIWLSVSNDLRHDSLRDLNDIGADMIKVHTDKENGRVQEGVIFGTYASLIGERHQAGAT-GCIVFDECHKAKNLYQANGKPSKTGTTVLELQRQLKQARIVYASAT........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 229
13 -9.260PF09848.7; A1A222_BIFAA/236-699; Uncharacterized conserved protein (DUF2075 topsan)  ali follow..  14  1...............................................SRLIFVQGVAGTGKTVLLSHLFYRIATEMKAYILVNHNQQM--HVYNQIASKLGLQKHFGEVALKPSQFINRFSEKTTSNRAIADKPRGKADVVLVDEAHLLLTQGDQGYSGK-----NMLHDLLRRAKVVIAV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 156

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.