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Query: 2pe4_A mol:protein length:424 Hyaluronidase-1, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst RSFRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQLGRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTTNHFLPLDELEHSLGESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGALLCSQALCSGHGRCVRRTSHPKALLLLNPASFSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCRCYPGWQAPWCERKSMWTGLast
1 -150.0002pe4_A mol:protein length:424 Hyaluronidase-1  ali model  100  1RSFRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQLGRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTTNHFLPLDELEHSLGESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFILNVTSGALLCSQALCSGHGRCVRRTSHPKALLLLNPASFSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCRCYPGWQAPWCERKSMWTG 418
2 -128.0001fcq_A mol:protein length:350 HYALURONOGLUCOSAMINIDASE  ali model follow..  27  1..TPDNNKTVREFNVYWNVPTFMCHKGLRFEEVSEKYGILQNWMDKFRGEEIAILYDPGMFPALLKDPNGNARNGGVPQLGNLTKHLQVFRDHLINQIPDKSFPGVGVIDFESWRPIFRQNWASLQPYKKLSVEVVRREHPFWDDQRVEQEAKRRFEKYGQLFMEETLKAAKRMRPAANWGYYAYPYCYNLTP--NQPSAQCEATTMQENDKMSWLFESEDVLLPSVYLRWNLTSGER-VGLVGGRVKEALRIARQMTTSRKKVLPYYWYKYDRRDTDLSRADLEATLRKITDLGADGFIIWGSSDDINTKAKCLQFREYLNNELGPAVKRIALNNNANDRLTV-DVSVDQ................................................................... 349
3 -121.0002atm_A mol:protein length:331 Hyaluronoglucosaminidase  ali model follow..  30  3.......RPKRVFNIYWNVPTFMCHQYDLYFDEVTNFNIKRNSKDDFQGDKIAIFY--DPGEFPALDGKYKKRNGGVPQEGNITIHLQKFIENLDKIYPNRNFSGIGVIDFERWRPIFRQNWGNMKIHKNFSIDLVRNEHPTWNKKMIELEASKRFEKYARFFMEETLKLAKKTRKQADWGYYGYPYCFNMSP--NNLVPECDVTAMHENDKMSWLFNNQNVLLPSVYVRQELTPDQR-IGLVQGRVKEAVRISNN-LKHSPKVLSYWWYVYDETNTFLTETDVKKTFQEIVINGGDGIIIWGSSSDVNSLSKCKRLQDYLLTVLGPIAINVTEAVN................................................................................. 331
4 -13.8005e6v_A mol:protein length:224 Integrin beta-2  ali model follow..  13  1.............................................................................................................................................................EECTKFKVSSCRECIESGPGCTW-------C-NFTGPGDPDSIRCDTRPQLLMRGC----AADDIMDPTSLAETQEDHNGGQKQLSPQKVTLYLRPGQ-AAAFNVTFRRAKGYSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDQVKVTATECIQEQSFVIRALGFTDIVTVQVLPQCERSLCHGKGFLE----------------------------------------------ICRCDTGYIGKNCE....... 221
5 -12.0004bdw_A mol:protein length:85 COAGULATION FACTOR XIIA HEAVY CHAIN  ali model follow..  15  1......................................................................................................................................................................................................................................................................................................GSEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDARLASQACRTNPCLHGGRCL----------------------------------------EVEGHRLCHCPVGYTGPFCD....... 80
6 -11.5001hre_A mol:protein length:67 HEREGULIN ALPHA  ali model follow..  16  3..........................................................................................................................................................................................................................................................................................................................................SHLVKCAEKEKTFCVNGGECFMVKDLSNP-----------------------------------SRYLCKCQPGFTGARCTEN..... 50
7 -11.3001tpg_A mol:protein length:91 T-PLASMINOGEN ACTIVATOR F1-G  ali model follow..  25  38.....................................................................................................................................................................................................................................................................................................................................SGRAQCHSVPVKSCSEPRCFNGGTCQQ--------------------------------------ALYFSDFVCQCPEGFAGKSCE....... 85
8 -11.0002vj3_A mol:protein length:135 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  15  6.................................................................................................................................................................................................................................................................................................DECSLGANPCEHAGKCINTLGSFECQCLQGYTGP-------RCEIDVNECVSNPCQNDATCL--DQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQVD..... 120
9 -11.0004xlw_A mol:protein length:124 Neurogenic locus notch homolog protein 1  ali model follow..  15  16..............................................................................................................................................................................................................................................................................................................GKCLNTLGSFECQCLQGYTGP-------RCEIDVNECISNPCQNDATCL--DQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQSG..... 117
10 -10.9001egf_A mol:protein length:53 EPIDERMAL GROWTH FACTOR  ali model follow..  22  1..........................................................................................................................................................................................................................................................................................................................................NSYPGCPSSYDGYCLNGGVCMHIES--------------------------------------LDSYTCNCVIGYSGDRCQTR..... 45
11 -10.8005fm9_A mol:protein length:157 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  15  56..............................................................................................................................................................................................................................................................................................................GTCHNEVGSYRCVCRATHTGP-------NCERPYVPCSPSPCQNGGTCR-PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTE...... 157
12 -10.8005fma_A mol:protein length:154 NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1  ali model follow..  15  53..............................................................................................................................................................................................................................................................................................................GTCHNEVGSYRCVCRATHTGP-------NCERPYVPCSPSPCQNGGTCR-PTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTE...... 154
13 -10.8003ltf_D mol:protein length:58 Protein spitz  ali model follow..  20  1............................................................................................................................................................................................................................................................................................................................................TFPTYKCPETFCLNDAHCFAVKIADL------------------------------------PVYSCECAIGFMGQRCEYK..... 49
14 -10.7001dan_L mol:protein length:152 BLOOD COAGULATION FACTOR VIIA light chain  ali model follow..  14  11..............................................................................................................................................................................................................................................................................................................GSLERECKEEQCSF-EIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVS..... 126
15 -10.6001aut_L mol:protein length:114 ACTIVATED PROTEIN C  ali model follow..  16  11............................................................................................................................................................................................................................................................................................................................................VLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQ..... 91
16 -10.4001whe_A mol:protein length:86 COAGULATION FACTOR X  ali model follow..  17  1............................................................................................................................................................................................................................................................................................ANSFLEEVKQGNLE-------RECLEEACSLEEARFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHC----------------------------------------KDGIGDYTCTCAEGFEGKNCE....... 82
17 -10.2001fsb_A mol:protein length:40 P-SELECTIN  ali model follow..  35  1...............................................................................................................................................................................................................................................................................................................................................TASCQDMSCSKQGECLET----------------------------------------IGNYTCSCYPGFYGPECEY...... 37
18 -10.2004d90_A mol:protein length:143 EGF-like repeat and discoidin I-like domain-c  ali model follow..  12  17.................................................................................................................................................................................................................................................................................................................GLADGSFSCECPDGFTDPNCSSVVEVASTSAGPCTPNPCHNGGTCEISEAYRGDTFICPRGFNGIHCQHNINECEVEPCKNGGICTDLVANYSCECPGEFMGRNCQYK..... 134
19 -10.1001pfx_L mol:protein length:146 FACTOR IXA  ali model follow..  10  8...............................................................................................................................................................................................................................................................................................................EFVRGNLERECIEEKCSFEEAREVFENKQYVDGDQCEPNPCLNGGLC--KDDINSYECWCQVGFEGKNCELDATCNIKNGRCKQFCKTGADSKVLCSCTTGYRLAPDQKS..... 123
20 -9.9704xl1_B mol:protein length:230 Delta-like protein  ali model follow..  23  139.......................................................................................................................................................................................................................................................................................TLTRLRYSYRVVCSDNYYG-------------DSCSRLCKKRDDHFGHYECQPDGTGKYCDQPICEQNGYCS-------------------------------------------KPDECNCRPGWQGPLCNEA..... 229
21 -9.8901fax_L mol:protein length:96 FACTOR XA  ali model follow..  25  2.............................................................................................................................................................................................................................................................................................................................................KDGDQCETSPCQNQGKCKDG----------------------------------------LGEYTCTCLEGFEGKNCELF..... 41
22 -9.5701p0s_L mol:protein length:138 Coagulation factor X precursor  ali model follow..  14  1............................................................................................................................................................................................................................................................................................ANSFLEEMKKGHLE------MEETCSYEEAREVFEDSDKTNEFWNK--YKDGDQCETSPCQNQGKCKDG---LGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDCHEEQNSVVCSCARGYTLADNGKA..... 123
23 -9.4904xlw_B mol:protein length:261 Delta-like protein  ali model follow..  1...........................................................................................................................SSSIFQLRLQEFANERGMLANGRPCEPGCRTFFRICLKHYQATFSE----------------GPCTFGNVSTPVLGTNSFVIRDKNSGSGR---NPLQLPLNFTWPGTFSLNIQAWHTPGDDLRPETSPGNSLISQIIIQGSLAVGKNWKSDEQNNTLTRLRYSYRVVCSDNYYGD---FGHYECQPDGSPSCLPGW---------TGKYCDQPICLSGCHEQNGYCS------------KPDECNCRPGWQGPLCNECIPHKGCRHGTCTIPWQCACDEGWGGLFCDQA..... 259
24 -9.3301nfu_B mol:protein length:195 COAGULATION FACTOR XA, LIGHT CHAIN  ali model follow..  10  2...............................................................................................................................................................................................................................................................................................................EMKKGHLERECME-EVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKD---GLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDCHEEQNSVVCSCARGYTLADNGKA..... 118
25 -9.1602w86_A mol:protein length:147 FIBRILLIN-1  ali model follow..  11  14........................................................................................................................................................................................................................................................................................NGVCKNSPGSFICECSSESTLDPTKTICIETIKGTCW-----QTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIVFPGVCKNGLCVNTRGSFKCQCPSGMTGRIC........ 146
26 -9.1604wm0_D mol:protein length:50 Coagulation factor IX  ali model follow..  21  3............................................................................................................................................................................................................................................................................................................................................IVDGDQCESNPCLNGGSCKDD----------------------------------------INSYECWCPFGFEGKNCELLE.... 44
27 -9.1201ob1_C mol:protein length:99 MAJOR MEROZOITE SURFACE PROTEIN  ali model follow..  10  1..........................................................................................................................................................................................................................................................................................NISQHQCVKKQCPQNSGCF----RHLDEREECKCLLNYKQE--GDKCVENPNPTCNENNGGCDADAKCTEEDSGSNG-----------------------------------KKITCECTKPDSGIFCS....... 93
28 -9.0001gk5_A mol:protein length:49 MEGF/TGFALPHA44-50 CHIMERA  ali model follow..  21  1..........................................................................................................................................................................................................................................................................................................................................NSYPGCPSSYDGYCLNGGVCM--------------------------------------HIESLDSYTCNCVIGYSGDRCEHAD.... 46

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.