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Query: 3o7b_A mol:protein length:244 Ribosome biogenesis Nep1 RNA methyltransferas, from PDB0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst RSDITSLYKKVGENLYFQGMGSAFVFLEASLELIPQKIRGHPAVRADAIRRGKRPEKILLDDSKHHTAMKSLEFREKRGRPDIVHQCLLLLLDSPLRDFEVYVHTLNGEIIWVNRETRLPRNYNRFVGLMEKLFEERRITAGDTTLIEFKDVGLRDIVRGRDVLLFREKGGRFEFSELLDGDVAVCIGAFPHGDFFEETLRELGEFKEVSLGTESYTSLYVTSRVLCEYERVRAHKVGLast
1 -84.800[S] COG1756 Uncharacterized conserved protein  ali follow..  40  2................SEKKRLHLIIADAELETVPEQILDHPAIVNYAKRRKRKPEKIILDSTYHHAALKQLEDGERRGRPDIVHICLLNALDSILNKLRVYVHTRNDYVIYIKPETRLPRNYNRFIGLMESLFEKGAVPEDLELLERKTLQELINEINPDAVFVMHEEGELMIPKNFGKKKPAVIIGGFPHGDFRSRV-----EGVKISLYKEPLMAWTIVNEVIVSYE........ 220
2 -83.400[J] KOG3073 Protein required for 18S rRNA maturation and 40S ribosome biogenesis  ali follow..  22  11....PNAKRMKTDNQLEDKKILYVVLEGCSLETAK-----------------VGGEYAILSSDKHANFLRKQKKDPADYRPDILHQCLLNLLDSPLNRLRVFFRTSKNVLVDVSPQCRIPRTFDRFCGLMVQLLHKLSIRAAETLMSVVKNPVSNHLPVGSRKMLMSFNVPELTMANKLDEPLVLIIGGIARGKIVVDYN-----DSETKISNYPLSAALTCAKVTSGLEEIWGI... 230
3 -7.600[L] KOG4793 Three prime repair exonuclease  ali follow..  12  1...........................................MGSQALPPGPMQTLIFFDME---------ATGLPFSQPKVTELCLLAVHRCALESPPT--RVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDR.................................................................... 128
4 -5.650[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  1.....................MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISPPHSDFYCKISMKGCLAVFRNMVEYCELNLLDNQTNLVNLRCKLETTKEAT--DQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARVNDKFMRTQLKLKPSEFEQYQVTKETVIT-FCIKEFRAFLLFAECLNASLTL... 230
5 -5.430[C] KOG4110 NADH:ubiquinone oxidoreductase, NDUFS5/15kDa  ali follow..  16  149.STVTGDEGKKPKKQKTENFPVHPVLYVIEIQYASQIEIGLEMIVVSGVNRPKMMHYSLLQKNNHENFGKDDQEVTYTIRYILVHPKIIVIKTK................................................................................................................................................ 241
6 -5.300[R] COG2969 Stringent starvation protein B  ali follow..  15  5..........................................................................QLTPRRPYLLRAFYEWLLD---NQLTPHL------VVDVTPGVQVPMEYAR----------------DGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGA............................................ 100
7 -5.190[T] KOG2313 Stress-induced protein UVI31+  ali follow..  14  56.EKTGSDSGAIENRASRMREKLQKELEPVELVIEDVSYQ-HAGHAGMKGRTDDETHFNVKIVSKGFEGMNLVK------RHRLVYHLLREELDTGLHALSIVSKTPSE.................................................................................................................................. 155
8 -5.130[S] COG1576 Uncharacterized conserved protein  ali follow..  16  48............................................................................................................................................DIARILQKEGEAMLAAVPKGNRIVTLDIPGKRWDTEELAVRDVSILIG----GPEGLAPACKAAADQSWSLSPLTLPHPLVRVVMAESLYRAWSITTN 150
9 -5.130[S] COG4728 Uncharacterized protein conserved in bacteria  ali follow..  18  32...................................RDKVRNMDLQAGLYRHYKGQNYRVLGVARHSETEEAL----------VIYQALYGEFGLWVRPLEMFTEA-----VEVD------EWVPRFVLV............................................................................................................. 105
10 -5.070[DK] KOG4333 Nuclear DEAF-1 related transcriptional regulator (suppressin) and related SAND domain proteins  ali follow..  11.GDVVVVPTEGNEGENPEDTKTQVILQLQPVQ--QGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAY---SKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDS...................................................................................... 162

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A., Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11;117(6):699-711. Review.