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Query: sp|Q99490|AGAP2_HUMAN Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens GN=AGAP2 PE=1 SV=2 (Range: 1-300), from H.sapiens

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSRGAGALQRRTTTYLISLTLVKLESVPPPPPSPSAAAVGAPGARGSEPRDPGSPRGAEEPGKKRHERLFHRQDALWISTSSAGAGGAEPPALSPAPASPARPVSPAPGRRLSLWAAPPGPPLSGGLSPDSKPGGAPSSSRRPLLSSPSWGGPEPEGRTGGGVPGSSSPHPGTGSRRLKVAPPPPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESEGKPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSLast
1 -17.400PF05934.9; CLCC1_RAT/3-541; Mid-1-related chloride channel (MCLC)  ali follow..  354...................SVPMLRHFRGPEREPPRALEPDDRRRQKELDYRFHGGAGDADFSYRGPAGSIEQGPYDKMHVCERDVLRQRQVNMRFPSGNKSPEVLRAFDLPDTEAQEHPEVVPSHKPSIVNTSLKETSELPRESTLAECSQCAKDGSGQVPSTAESSPIVEKAQLKTDSECRPHSTEAAAAAARGTDPVSSPCG............................................................................................... 539
2 -17.000PF11725.6; Q887C9_PSESM/17-1794; Pathogenicity factor  ali follow..  1................................................TVTPDARAATDLQERAEQPRQRSSHSLSSVGKRALKSVGKLFQKSKAPQQKAATPPTAKNVKTPPPASNVATPRNKARESGFSNSSPQNTHSAPKSILRNHPNQASSSGAQTHEIHPEAAPRKNLRVRFDLPQDRLERSPSYLDSDNPMTDEEAVANATRQFRSPDSHLQGSDGTRISMLATDPDQPSSSGSKIGDSDGPIPPREPMLWRSNGGRFELKDEKLVRNSEPQGSIQLDAKGKPDFSTFNTPG.. 250
3 -14.700PF15782.3; H2M7V5_ORYLA/1-1933; Gene regulated by oestrogen in breast cancer  ali follow..  11  176......STQPKKQKHLYRNKQGILVKGAPICWRVNVINAGCGSCCSVSSSSFSLLLCCSPISFAPSATVMKRSDTGRIGAKEIGMAGPHVDQQTTDLAHTLINGNHSAPSSAQSSLNQPGRSSAPATHTNAGPPKKRHKGWSPDLSANSLQESTVKSPPASLSLSTSVSSVVTPSAAIFPPLQLSVTVPDQLLHTCRLQPVILKGHGPLPQLTGNVRDILVSSLLHSCYMSSQTLPRIYQHYGPSPIQPLSTEGPEQVPLVEDLEQIFMRSWRESHLSEIRQFQQPQAPAVQSQQTLTPS 487
4 -14.500PF05297.9; LMP1_EBVB9/1-386; Herpesvirus latent membrane protein 1 (LMP1)  ali follow..  11  187....................................................................................................HGQRHSDEHHHDDSLPHPQQATDDSGHESDSNSNEGRHHLLVSGAGDGPPLCSQNLGAPGGGPDNGPQDPDNTDDNGPQDPDNTDDNGPHDPLPQDPDNTDDNGPQDPDNTDDNGPHDPLPHSPSDSAGNDGGPPQLTEEVENKGGDQGPPLMTDGGGGHSHDSGHGGGDPHLPTLLLGSSGSGGDDDDPHGPVQLSYYD 386
5 -14.200PF05616.11; Q9JYD9_NEIMB/10-516; Neisseria meningitidis TspB protein  ali follow..  258......................NPDKYIKATGYPGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPNPNENPGTSPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPGRTNGRDGKDGKDGKDGGLLCKFFPDILACDRLPESNPAEDLNLPSETVNVEFQKSGIFQDSAQCPAPVT............................................................................. 458
6 -13.900PF05460.11; M9MXX4_ASHG1/10-395; Origin recognition complex subunit 6 (ORC6)  ali follow..  12  66...............................................EPELQYYREKIPLEPRKTVKLVGLFKQTLWTSSPVRNLNLSPSPKKDGGRLSARDPVELRAELFGTPVKRAGAVTLPGAGELSPTKQLSPSKPMSPVKPSPRRRLAFEDEDEDYEPDASPQPSPRRSIFPGGFEPDPDESEFDSPTKSPFKSPTRSPTKSAQSSPRKKRGEYNQWNMLYKKYYRITPEE................................................................ 254
7 -13.800PF09786.7; B9HQ86_POPTR/12-670; Cytochrome B561, N terminal  ali follow..  10  98..............................................................................AGVRITSPSKDARDQPQLTNRQLGLIGVKPKVEPVVSESSKKPPKSNPTSSASNVLVPIHQLITCSHQKSRVGSDKSNAGSGNKMASFSTPSKSRNSPSFYLVPGANSPLPSVQSSPAIDSAVSTPWSDKRASYTKEIRTEEQLEQFLAEVDEKISESAGKYATPPPTIGGFGMASPNTVASPANTPGVTRSTPLRPVRMSPGSQKFTTPPKIGEGDLPPPM 319
8 -13.600PF04642.10; Q9C631_ARATH/201-502; Protein of unknown function, DUF601 topsan  ali follow..  13  6..............................................................................EDSKLRSLEKTKYQPSDSGSRPETPTSVSAGKKPETPTSGSGKALKDPAGKDPEKRAADKKRKQPEEISHSPPRSSRPRQEEKGAKLKGVVEDAPQNLVVLSSRESETRESERRNVPLPAPPMTFADTMRTLVPPGSAIAPFDE.............................................................................. 149
9 -12.500PF08549.8; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)  ali follow..  13  462........................EPAPEPVKEPSPVPPPASSLPPAAGADTGALGSRRPSQAGSTHSGVMVGDSDIDMGGTAAGLLDEMHTGFSANSTPLNNFPTPQTHMSALNSTAGTPANANAPSPAPVPPTIPEETETQASAGASAGAAEDVTMGNTGSTKNTPATAPDHGTGSGEWVVVPKGGTSPDPGAGAATSTGATEGDEPKAAAKIPSAAGTPVETQTPGGFSSLGDLDSAGDAMASYGASMADG.............................................. 691
10 -12.300PF05782.9; H0WRX2_OTOGA/1-562; Extracellular matrix protein 1 (ECM1)  ali follow..  10  1MGTMSRA--------------AWVLAYLAVASVASEGDLKAPGQRELRPEHFMQHFHEVGYAAPPSPPLSQSLPMDHPDASQHGPLLEGQSEVQPLPPQEAIPVQEEEMPPPQVPLEKTDLPHPQEAIPAQEENLPPPQLSIEQKEVEPALSQAEMIFQPKQREGKPAALVSQSHPEPETWNPAQHCQRGRSRGGWSHRLDGFPPGQPSSDNLNQICLPDRQHVLYGPWNLPQSG................................................................. 221
11 -11.100PF08580.8; V5HV84_BYSSN/491-1186; Yeast cortical protein KAR9  ali follow..  11  432...................SIITMDSPATGSVVDTPGSSPASSVVLSNGNGRKGSSTPNVGSSSRRGSSVASTNRKRYSGIPQGAATLSAGRRSSIPRASFSGSLTSPTRSQTNPSFTPRPASRTSTAPTKTPDNRPRWNSSTNTNDLNIGTHKTLSATTPSRNPNRNSRSNIPTPSPLSREASRSPVPPHMRSSSRAMSRLASPTPNRLYSPTPSRSILDPPPYSKLRKQSTPNLPTGARNRQSYAGISITRSSPVEDRTKTQRPETSLGHSTASRRLSGIP................. 696
12 -11.000PF05609.10; G1QDE7_MYOLU/26-480; Lamina-associated polypeptide 1C (LAP1C)  ali follow..  4................................ENDPSINSQAQETTVTASTTKEAQILSPASGLNKDHQEVETIGSGSADTSNQSESPDEASYGNYPKDKTELKTNQSFQDGKLGHQLSSKKSGGEESLHPEPSCCPSEEVGRADAQLGSSSVDLPEEASNRPEASQKPLAVDPQGVRGPDHSSAGPESQGTRRRRLVEPGEGSHQQEIQTLEENKEDAQDAIR............................................................................ 195
13 -10.800PF15324.4; H9GLI0_ANOCA/127-1404; Hedgehog signalling target  ali follow..  10  954................................................GDRENHRAAPVTVVPSAAALLPEKETLLPTPLATPEATPPQSPPPALNEQFPVKTPTSSPSVTEMDGEQPQTGPEAAAASVVYTPVATPVATPPKIATPTPPVSERAPNREAMEKPPPPNPWEDAELPLEEEKPSPQSEEGAYPSRAVIMSVAKHEEPDSLVLPASVPIAPQDLQSQEPRARSPSVQSPSSGPSTEESLTTTETETTDKPISEGE..................................... 1168
14 -10.400PF17076.3; SBE22_CANGA/1-813; SBE2, cell-wall formation  ali follow..  3..................................RPRSNLGTLPEEPSVESKSGRTLAGITSSRKESGMRSRTSSGSAQAVGLGLGRRPSDNLFHGHADPLDTMQMLSEALPQPPKIEHGMRRERPISNDSIMTTKSSEIFSTSSSDTQSNISVATNDSEDHSFGMDKSVDNSSTNATLTNRSIENRSNGDSYSIGEKSDVSVNRSTKSGNNPLQRTQSETISVNMSHNRSMNGAMKQPTPPFMGKNSSIPNLRYNSQPQQDNRSVPNGEFGSKLYNLSNSTSAIIPNAGTGSKLALTPS 268
15 -10.200PF05518.9; CAPSD_HV19S/10-772; Totivirus coat protein  ali follow..  13  559...............................LNPEHLPAAHEMADTTVTMTVGRPIGIAPGRSNAGDNQARRARTRASVELSAASRRARVFGRPDVGEMPTLTSAPAPIPASPAYDGNRGGEAGGVTGRGNNRSAAPGHASWSERQADGVPVNVTPHHNALRAPPFPRQQGALGGGGNVPLPPAPGAAPPPPPGPPNGPPAGPPPSDDGSSNPAAPVPTAIHAPPAAAQADRAEG................................................................. 762
16 -10.200PF07174.9; V5XE16_MYCNE/1-285; Fibronectin-attachment protein (FAP)  ali follow..  15  3.....................................................................................................QSDVNSSHRRRRTAGLLAAAAAGATAAALTLPVAVSHAEPVPAPPPPVPAEPAPAPGTPAPAPGAPAPTPLPPGVPPPPADPNAPPVDPNAPPPPAPEPGRVDNAAG............................................................................................ 109
17 -9.820PF04388.10; F7E2N6_XENTR/7-705; Hamartin protein  ali follow..  289........................TEIGCNYGSNASTPFSTPRMCAHSASIHSGGIELLQDSIWSPSTICGMTTPPNSPANVLADAAHSSSRPHSKVLYTPVGGKITPLGTPATSPPPPSNSEECTPAAGASLTLTPHKKNESFDPGRSLVNRQLLSKGEKSADESPKTQKTVYLSELPDIIGDLAADHNSTEEEQETRAAICQELSQITTADPEPTVLRGGFDSPFSLRCDSQPSSQKKFPSYGVGHIPEHSAPNKLHYSAPHDSSKQAFTPIEPPNGTENAADSGKPPSNNSLPSAVD 564
18 -9.270PF15724.3; L5JX75_PTEAL/24-275; TMEM119 family  ali follow..  120........................AGGPQAFSEVPDKDPDGRPEEALDSSQQLQADILAATQNLKSPARVASSSGNGARVTEGKSEEEEKGSQEADREAEGRGVSVERAEVAEDPCLAVVEGAVGAGEGPGEPEAAPSLSQEAEGPAGPPESPCACG............................................................................................................................................... 252
19 -9.270PF16214.3; F1NEC3_CHICK/1-415; Adenylyl cyclase N-terminal extracellular and transmembrane region  ali follow..  1MSRSNSVSPPGFGGPAPWAATEQHRSAWGEAEARANGYSYPPPPNRSSGKKASRMASRWRSEEDYEPQASRSRGESGCKMMMSFRSKSAWQEHGDESRRHRSRHPPGGDSPAAPNNASPREQGEVRPRSVELGLEEKRIKAKIEELEEDDGDDGDSEVA............................................................................................................................................. 159
20 -9.180PF15402.4; A1CEP5_ASPCL/31-917; N-terminus of kinetochore NMS complex subunit Spc7  ali follow..  12  566................................................................................PADVEADDEAQDQGDAIPEMDHEQIGSSPFQENVRMSPSKPPISFHVAPVASESGSPSLASVRSRSTRQSLGRRMSNTPSLRSPQASPVKNTTAPAENSTPQNNQSLTLSQTPPSNKSARSASSKKLFQPELREIASQRKSPGRKSIFGQTGTTGDSTPLFPLRPHEKRRSSGLGIDKEGLGSPRVAAILDKRRSIGEDAPR---PQEQPKSGVRFEDPL 784
21 -9.080PF08639.8; Q4WT42_ASPFU/290-812; DNA replication regulator SLD3  ali follow..  267.......................................VSGAISPLAKQSSGTKKASRTEPGKPTERQSSQRHPRRSLQRVLTDQQTASQARPRSLGRSNTVPSQAGAKRESMEPLLPVLSVSARGGIQKPKRVENREVDLNAVARQHEAKLRKVQMLMEQKKELDAAINALRKPNRELVAKDIVEDAVKRASGGSSRKPKNPVRNPFGQGVQVMATPKGSRKKDAVMGLAPPFKNIVRSSPSKSGSSPFAS-----EPQVVPASTLRPRFISNTLASESMAAPGSVLGDMGAIQETPS 522

FFAS is supported by the NIH grant R01-GM087218-01
8 2 9 2 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I, Jaroszewski L, Ye Y, Godzik A. The interplay of fold recognition and experimental structure determination in structural genomics. Curr Opin Struct Biol. 2004 Jun;14(3):307-12.