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anford Burnham Prebys Medical Discovery Institute
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Query: gi|15644639|ref|NP_206807.1| orotidine 5`-phosphate decarboxylase (HP0005) [Helicobacter pylori 26695], from H.pylori

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQLCVALDLEKKEDNLSLLQELKGLDLWAKVGLRSFIRDGAVFLDEIRKIDENFKIFLDLKLYDIPYTMANAALECAKLDIDMLTVHLSSAKSALTALMQRLNALKKRPLIMGVSALTSFSEEEFLMVYNAPLKTQAIKLSAMGKESGIDGVVCSVFESLAIKEALGKDFLTLTPGIRLDQNDKEDQERVANAKEAKQNLSDFIVVGRPIYQAKEPREVVLELLKDCLast
1 -5.750 VFG043390(gi:15646189) (pdxJ) pyridoxine 5`-phosphate synthase [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]  ali follow..  12  63SPLPINIECSINAEITDFLCSLK-NEVTTEGGLDCSLKGLGEVIRAYHNKGIEVSLFIDPLKDAL--------HFAREHQVKQVEFHTGVYANLHNALYSNANNQIH-----AISVLKDKSPKELKEELHNAF-LQLRRMSKEAFFMGI-----------TACAGHGLNYTNVKE--------------LLKIPSLRELNIGHSVVSKAV................. 245
2 -5.570 VFG045520(gi:52841543) (legC1) Dot/Icm type IV secretion system effector LegC1 [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]  ali follow..  10  856.....ALEINTENDRGAIQFNEEKLRLILKQGINIIQQSFPKYMEHVNSLENNPTVYFHLEVRTAIEVLKDLCTKDLCPKVFVLDT-TSATEAQIEDFLNVFNQQDKIPILVTAASMVKHSEFGL-DLWQGGINKAYLSEKSEKNENSQNEFARFITELKNVTKGTEPGFTHVREAMNNINEAIKDSQDNSEPQDATCKDDVQNIPTNPISEESNRKEEGQIINREL 1090
3 -5.040 VFG002241(gi:49476021) (bepA) Bartonella effector protein BepA [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]  ali follow..  10  316..................LVPLTKLEIAEMVAEDAFVHTCRDQICSLSKIVYGSQGVLNKNIIEIIKNPSKGQQLATQIERTPYSVHSLAGFDLFKTGARVRAEKHVALLSCAVANFTHAVKHARQEITKEHQAEQNRLRQEVPMPS-------SLQDLLSLPKEFQQKALGVSPLLQKELTSQKVNSRLSSSEQRALRENNHETLAKNLGVSEQKAKEITKTVMK. 521
4 -4.840 VFG002244(gi:49476024) (bepC) Bartonella effector protein BepC [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]  ali follow..  304..................LPPLTNEELAKRFTDNCGVESYRQEVEHLSKRVYGKSQALNEMIESINIDPSLGAEFADQIAQNPKSFCKLAGRKILRSPSRRRAEEAVPQLCEALKSYADMAQHTMENLIEQHQREQRRIAHSVEKPG-------DLQQLFTLSPEQQREVLSHSPTLQKQLHT---QNRLSSEEHRAIQENNPLKLSCMLGVSESKAKEITKAVKQ. 509
5 -4.570 VFG001988(gi:15792733) (cysC) adenylylsulfate kinase [Capsule (VF0323)] [Campylobacter jejuni subsp. jejuni NCTC 11168]  ali follow..  10  8................................................................................IWLTGLAGSGKTTIGQALYEKLKLKYKNLIYLGDELREILGHYAYDRQGRIDMALKRAKFAKFLNDQGMMVIVTTISMFNEIYDYNRKNYYEIYIECDMHELIQRDQKGLYTKALNKEI-DNVVGVDIEFDKPEADLVINNSCRNN. 156
6 -4.520 VFG045464(gi:26248250) (tcpC) Tir domain containing protein TcpC [TcpC (VF0413)] [Escherichia coli CFT073]  ali follow..  12  171.....................................................YDFFISHAKEDKDTFVRPLVDELNRLGVII-EQTLEVGDSLRRNIDLGLRKANYGIVILSHNFLNKWTQYELDSLINRAVYDDNKIILPIWHNINAQEV........................................................................... 272
7 -4.410 VFG001299(gi:21281855) (cap8C) capsular polysaccharide synthesis enzyme Cap8C [Capsule (VF0003)] [Staphylococcus aureus subsp. aureus MW2]  ali follow..  13  56...........KSCLNHIESLEEVQALNLKFGQEIRIT--DQILNDIDRINDSRYLLIEFPSNEVPHYTDQLFFELQSKGFVPIIAHPERNKAISQNLDILYD-------LINKGALSQVTTASLAGISG----RKIRKLAIQMIENNLTHFIGS........................................................................ 193
8 -4.370 VFG001366(gi:15900276) (cps4B) capsular polysaccharide biosynthesis protein Cps4B [Capsule (VF0144)] [Streptococcus pneumoniae TIGR4]  ali follow..  15  72.........................DLVIAYGAEIYYT--PDVLDKLEKLNDSRYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNE-KRVRELIDMGCYTQVN-----SSHVLKPKLFGERYKFMKKRAQYFLEQDLVHVIASDMHNLDGR----------PPHMAEAYDLVTQKYGEAKAQELFIDNPRKIVMDQLI................. 243
9 -4.350 VFG002243(gi:49476023) (bepB) Bartonella effector protein BepB [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]  ali follow..  11  314..................LAPLTKSECARTVAQTSHVLTAQKKVRQHSKIVYGNANTLNEQIEEITKNPELGQLLADQIRQTPHSLSPLAGFSLLQNPARANARNHLDALATTVANYAHIVEHTYHVITQKHQIEQERLGKTVEKPS-------NLQNLFALSPEQQREILSQSPQLYQELRT---EHRLSSNEWSAIKNKDYETLAQSIGVSEQTAREITNTVQK. 519
10 -4.320 VFG001351(gi:22537332) (cpsB) CpsB phosphatase [Capsule (VF0274)] [Streptococcus agalactiae 2603V/R]  ali follow..  10  72.........................HLQILYGGELYYT--SDMLEKLKLLNNTKFALIEFSMQTSWKDIHTALSNVLMLGITPVVAHIERYNALENQK-ERVKEIINMGCYTQIN-----SSHILKQKLFNDKHKRFKKRARYFLEENLVHFVASDMHNLDVR----------PPFLAEAYKIICRDFGKERANQLFIENAQSILKNHYI................. 243

FFAS is supported by the NIH grant R01-GM087218-01
1 1 7 8 9 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zhang B, Jaroszewski L, Rychlewski L, Godzik A. Similarities and differences between nonhomologous proteins with similar folds: evaluation of threading strategies. Fold Des. 1997;2(5):307-17.