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15644638
Query: gi|15644638|ref|NP_206806.1| carbonic anhydrase (icfA) (HP0004) [Helicobacter pylori 26695], from H.pylori

Results of FFAS03 search in PfamA26U
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVICNMGNVNPPKTSYKESLSTIASIEYAIAHVGVQNLIICGHSDCGACGSVHLIHDETTKAKTPYIANWIQFLEPVKEELKNHPQFSNHFAKRSWLTERLNARLQLNNLLSYDFIQEKASKNELKIFGWHYIIETGRIYNYNFESHFFEPIGETIKQRKSHENFLast
1 -85.000PF00484.14; Q28W87_JANSC/42-203; Carbonic anhydrase  ali follow..  26  1................................AMVIACCDSRVAINSVFGQRTGELFVHRNIANLVPPYTPDGNHHGTGAAVEFAVKHLKVEHILVMGHSNCGGVAGCISMCEPEFDQEESLIGRWLDVLRPGYQTVSDI----EDPKGRQTALEKEGIHVSLENLLGYPFVKSAVDAETLSLHGLWADIADMDL.......................... 162
2 -8.010PF07519.6; Q8RLZ8_ACIAD/88-580; Tannase and feruloyl esterase  ali follow..  342...................................IPPDELNLDK---LRLHGGKMIVVQGTADGVFSVDDTQNWYDKLMAKYKSSSLGDAQSFRVPGMNHSRG------GLATDQFDALTALVNWVEYGQAPDQILASARGVGNASGEINSELPSSWSANRTRPLCPYPKIARYNGTGDSE....................................... 483
3 -7.830PF07224.6; CLH1_CITUN/19-322; Chlorophyllase  ali follow..  17  36...................IIVTPAEKGTFNVILFLGTSLSNKSYSKIFDASHGFIVVAPQLYTSIPPPSATNELNSAAEVAEWLPQGANVSLVAVMGHS--GGQTAFALSLRYGFGAVIGL................................................................................................... 150
4 -7.660PF08204.6; Q9Q8V0_9POXV/10-120; CD47 immunoglobulin-like domain  ali follow..  10....................FVHLTVGNKVTVMPYTVCNTTITLECNLDEL------IYKDINSIHVKWLFYTMDDTISNITNGSFIKFDFAKNLS-GNYTC---EAYSDLNSVKNVIALNLVHQWFSREE.......................................................................................... 110
5 -7.400PF11187.3; Q8G7D3_BIFLO/154-387; Protein of unknown function (DUF2974 topsan)  ali follow..  14...................AVVEHINQGEQTQFAAATFQLPDGHKRRKPTYKGTLVISFRGTDDSLIGWKEDYPVPAQRSASAYLDMVAR-GPIILVGHS--GGNLAIYAAMNADPKVRKRIQHVYSLDGPGFPPEIVTSPAYRTIQPKVTKIVPSSSIVGMIFETPEPCRVVSSDSDGIMQHSAFTWLLDGDQFITEPDLSSSSQLFNEELNHWIAT... 219
6 -7.050PF08538.5; Q5KNQ0_CRYNE/1-293; Protein of unknown function (DUF1749 topsan)  ali follow..  31VVFIGGLTNGLGAV-----PFTYPLSDALGKAGWKLIQFHWS---------SAYGGYGTGSLDRDR---------EEMQALVKYLKTTGGLSKVIIMGHS--GSQNVMHYLSSSINNDPAYHVDGGIMQAPVSDREVCAKDKPYCDYLSLAEEMVKKGRGHEIMPDEFCKKAGFGGVEMKMTAYRLW.................................. 193
7 -6.750PF12740.2; C0PR35_PICSI/37-294; Chlorophyllase enzyme  ali follow..  15  7...................LLALPAQPGEYPVLLFFGYLLLNSFYTQLLQHIASHGYIAIAPQMYCVTGADATPEIDAAAICNWLLQGLDFQNVAMAGHS--GGKVAFGLALDRTSQTT...................................................................................................... 117
8 -6.700PF06028.6; Q8Y8F3_LISMO/27-272; Alpha/beta hydrolase of unknown function (DUF915 topsan)  ali follow..  10  5......................PKAANDSIPTIFIHGYRGTDRSLHGMIRR-TGTYNKKEKNPLINIVFEDNRATLPQQSVMSYLQQNYAIKKFNAVGHS--GGGAWVSYLASYEKNKSYPQVNKIVFLAVP......................................................................................... 141
9 -6.670PF05290.6; Q0ILB1_NPVLS/143-285; Baculovirus immediate-early protein (IE-0)  ali follow..  1MENLYQIELYKLNPYLKQLLAILNLFVNDACCKKYTRIAKDILEVSLKRSQEQLDCVQRITKTVQVMNVFLETPLYECGICTEASTEATFLKPNECCGFKICNVYANMWKFSKSAVHPVCPVCKTSYR............................................................................................. 134
10 -6.370PF04263.11; Q97NN8_STRPN/28-146; Thiamin pyrophosphokinase, catalytic domain  ali follow..  2...RGHYRTDFDAFVGVDRGSLWVLEEDLPLALA-VGDFDS---------VTEEERQVIQKGAQYFVQARPEKDDTDLELALLTIFEQNPQAQVTIFGHM-LANVFLPSNPKLAPYMHQIEIEDG................................................................................................ 119

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.