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Query: gi|15644643|ref|NP_206812.1| chaperonin GroEL (HP0010) [Helicobacter pylori 26695], from H.pylori

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKEIKFSDSARNLLFEGVRQLHDAVKVTMGPRGRNVLIQKSYGAPSITKDGVSVAKEIELSCPVANMGAQLVKEVASKTADAAGDGTTTATVLAYSIFKEGLRNITAGANPIEVKRGMDKAAEAIINELKKASKKVGGKEEITQVATISANSDHNIGKLIADAMEKVGKDGVITVEEAKGIEDELDVVEGMQFDRGYLSPYFVTNAEKMTAQLDNAYILLTDKKISSMKDILPLLEKTMKEGKPLLIIAEDIEGEALTTLVVNKLRGVLNIAAVKAPGFGDRRKEMLKDIAILTGGQVISEELGLSLENAEVEFLGKAGRIVIDKDNTTIVDGKGHSHDVKDRVAQIKTQIASTTSDYDKEKLQERLAKLSGGVAVIKVGAASEVEMKEKKDRVDDALSATKAAVEEGIVIGGGAALIRAAQKVHLNLHDDEKVGYEIIMRAIKAPLAQIAINAGYDGGVVVNEVEKHEGHFGFNASNGKYVDMFKEGIIDPLKVERIALQNAVSVSSLLLTTEATVHEIKEEKAAPAMPDMGGMGGMGGMGGMMLast
1 -157.000[O] COG0459 Chaperonin GroEL (HSP60 family)  ali follow..  61  1MAKQLLFNEEARKKLLSGVEQISSAVKVTLGPKGRNVLLEKGYGAPTVTKDGVSVAKEVELEDPFENMGAQLLKEVATKTNDVAGDGTTTATVLAYSMVREGLKAVAAGMTPLELKRGMDKAVAIAVDDIKQNSKGIKSNEEVAHVASVSANNDKEIGRILASAIEKVGNDGVIDVDEAQTMETVTEFVEGMQFDRGYISSYFVTDRDRMETVYENPYILIYDKSISTMKDLLPLLEKIAQTGRPLLIIAEDVEGEALATLVVNSLRGTLKTCAVKAPGFGDRRKEMLEDIAILSGGQVISEDLGLKLESADIALLGQAKSVKVDKENTTIIDGSGKSKDIKDRIEQIKKQIEASTSDYDSEKLKERLAKLSGGVAVIKIGAVTEVEMKEKKHRVEDALNATRAAIEEGIVAGGGLALIQAAAALESGLTPDEAVGFKIVRRALEEPIRQISENAGIDGAVVAEKAKEKR-GIGFDASKMEWVDMIKVGIIDPAKVTRSALQNAASVSGLLLTTECAIAAIPEKSSSPPAPDMGGMGGM....... 543
2 -149.000[O] KOG0356 Mitochondrial chaperonin, Cpn60/Hsp60p  ali follow..  51  14AAKDISFGIGARAAMLQGVSEVAEAVKVTMGPKGRNVIIESSYGGPKITKDGVTVAKSISFQAKAKNIGAELVKQVASATNKVAGDGTTCATVLTQAILIEGCKSVAAGVNVMDLRVGINMAIAAVVSDLKSRAVMISTPEEITQVATISANGEREIGELIARAMEKVGKEGVITVADGNTLDNELEVVEGMKLARGYISPYFITDEKTQKCELENPIILIHEKKISDINSLLKVLEAAVKSSRPLLIVAEDVESDALAMLILNKHHGGLKVCAIKAPGFGDNRKASLDDLAVLTGAEVISEERGLSLEKIRPELLGTAKKVTVTRDDTIILHGGGDKKLIEERCEELRSANEKSTSTFDQEKTQERLSKLSGGVAVFKVGGASESEVGERKDRVTDALNATRAAVEEGIIPGGGVALLYATKALDQTENEDQRRGVQIVQNALKAPAFTIAANAGYDGSLVVGKLLEDDCNFGFDAAKGKYVDMVKAGIIDPVKVIRTALTDAASVSLLLTTTEASVLVKADENTPNHVPDMASMG......... 553
3 -34.200[O] KOG0361 Chaperonin complex component, TCP-1 eta subunit (CCT7)  ali follow..  18  22.......GRGQLLSNINACVAVQDTIRTTLGPLGADKLMVDDRGEVVISNDGATIMKLLDIVHP----AAKTLVDIARAQDAEVGDGTTSVVVFAGELLREARTFVEDGVSSHLIIRGYRKAAQLAVNKIKEIAIHLDLSDELTKCASTAMNSSTFFTKMVVDAVLTLDQEDLIGIKKVPG--EDSLLVKGVAFKKTFSYAGF----EQQPKFFKNPKILCLDVELELKAEIFSKLEAIVATGAKVVLSKLPIGDLATQYFADRDIFCAGRV-----------AADDLNRVVQAVGGSIQS-----TCSNIEEKHLGTCDTFQIGGDRFNLFEGCPKAKTCT-----------------------------------LILRGGADQFIAEVERSLHDAIMIVKHALKNNVVAGGGACEMELSKYLRDTISGKQQNFIAAFARSLEVIPRQLCDNAGFDSTNILNKLRKGEMWAGVDMDSEGVANNFEKFVWEPSTVKSNAILSATEAATLILSVDETIKNEPSQQPQAPQGALPPGAANRIMRGR. 552
4 -32.300[O] KOG0358 Chaperonin complex component, TCP-1 delta subunit (CCT4)  ali follow..  21  26.......REDIRFANINSARAVSDAVRTSLGPKGMDKMISTANGEVIITNDGATILNKMEVLQP----AAKMLVELSKSQDSAAGDGTTTVVVIAGALLKECQSLLTNGIHPTVISDSLHKACGKAIDILTAMAVPVELTDRDSLVKSASTSLNSKVVSQYSTLLAPLAVDAVLSVIDPEKPEIDTHTVKGLVFDKK------VSRAAGGPTRVENAKIAVIQFQISPPKTILGMIKKIKATGCNVLLIQKSILRDAVTDLSLHYL-AKAKIMVIK-------ERDEIEFVTKTLNCLPIA-----NIEHFRAEKLGHADLVSLGDGKILKITGIKDMGR----------------------------------TTSVLVRGSNQLVLDEAERSLHDALCVVRCLVSKRLIAGGGAPEIELSRQLGAVLHGMEGYCVKSFAEALEVIPYTLAENAGLNPIAIVTELRQGEINAGINVRKGQITNILEENVVQPLLVSTSAITLATECVRMILKIDDIVT........................... 534
5 -32.100[O] KOG0357 Chaperonin complex component, TCP-1 epsilon subunit (CCT5)  ali follow..  19  30.......GLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQ----IAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVKDTEPLIQTAKTTLGSHRQMAEIAVNAVLTVADMERRDVDKVGGRLEDTKLIKGVIVDKDFSHP-------QMPKKVEDAKIAILTCPFEPPKPFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWV-----------GGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVT-----------------------------------IFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNVVYGGGAAEISCALAVSQKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKLGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE..................... 541
6 -32.000[O] KOG0359 Chaperonin complex component, TCP-1 zeta subunit (CCT6)  ali follow..  17  16.......AQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHP----TASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREDRETLIDVARTSLRTKDVLTEAVVDSILAIKKQDIEIMEMKHKSETDTSLIRGLVLDHGARHP-------DMKKRVEDAYILTCNVSLEYEKTIEDRVKKIIELKRKVVINQKGIDPFSLDALSKEGIVALRRA-----------KRRNMERLTLACGGVALN-----SFDDLSPDCLGHAGLVTLGEEKFTFIEKCNNPRSV-----------------------------------TLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGVVPGAGAVEVAMAEALKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG................... 531
7 -31.700[O] KOG0360 Chaperonin complex component, TCP-1 alpha subunit (CCT1)  ali follow..  19  22.......GDDIRNQNVLATMAVANVVKSSLGPVGLDKMLVDDIGDFTVTNDGATILSLLDVQHP----AGKILVELAQQQDREIGDGTTSVVIIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSDTLGKETLINIAKTSMSSSDFFSNMVVDALLAVKTQNAVNVLKAHGKSTESLLVPGYALNCTVASPKRIAGGNVKIACLDLNLQKARMAMGVQIN-VLERVKKIIDAGAQVVLTTKGIDDLCLKEFVEAKIMGVRRC-----------KKEDLRRIARATGATLVSSMSNLEGEETESSYLGLCDEVKFSDDECILIKGTSKHSSSS-----------------------------------IILRGANDYSLDEMERSLHDSLSVVKRTLESGVVPGGGAALNIYLDNFATTVGSREQLAIAEFAAALLIIPKTLAVNAAKDSSELVAKLRSYHAAYGLDLIRGKIVDEIHAGVLEPTISKVKSLKSALEACVAILRIDTMITVDPEPPKEDP................. 556
8 -31.000[O] KOG0364 Chaperonin complex component, TCP-1 gamma subunit (CCT3)  ali follow..  17  17.......GRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDVAHP----AAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYIEKNIHPVIIIQALKKALTDALEVIKQVSKPVDVENDAAMKKLIQASIGTKYVIHWSEKMCELALDAVKTVRKDLGQTVEGEVLKGVLLNKDVVHP-------KMSRHIENPRVVLLDCPLEYKKGVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCSVLRRV-----------KKSDNNRIARVTGATIVN-----RVEDLKESDVGTNKVEMIGDEYFSFLDNCKEPKACT-----------------------------------IMLRGGSKDILNEIDRNLQDAMAVARNVMLSPLSPGGGATEMAVSVKLAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRQGNFTTGIDGDKGKIVDMVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGVRKQE..................... 534
9 -30.600[O] KOG0362 Chaperonin complex component, TCP-1 theta subunit (CCT8)  ali follow..  16  19.AKHFSGLEEAVYRNIQACKELAQTTRTAYGPKGMNKMVINHLEKLFVTNDAATILRELEVQHP----AAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVKNLRDIDEVSSLLRTSIMSEVFLAKLIAQACVSIFPDNIRVCKILGSGISSSSVLHGMVFKK---------ETEGDVTSVKDAKIAVYSCPFDGMITMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLN-----------SKWDLRRLCKTVGATALP-----RLTPPVLEEMGHCDSVEVGDTQVVVFKHEKEDGA----------------------------------ISTIVLRGSTDNLMDDIERVVDDGVNTFKVLTRDKLVPGGGATEIELAKQITSTCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQGLDIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKD............ 541
10 -23.000[O] KOG0363 Chaperonin complex component, TCP-1 beta subunit (CCT2)  ali follow..  18  2..........ARLSSFIGAIAIGDLVKSTLGPKGMDKILGRNAGHVEVTNDGATILRAVGV----DNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHDFFANLAVDAVMRLKGSGELKSQIIKKSGGTLGDSFLDEGFLLDKKHQPQRIENARILIANTPMDTDK-MKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHA-----------DFDGIERLAYCTGGEIVS-----TFENPSLVKLGECDVIMIGEDTLLRFSGVKLGEACT-----------------------------------IVIRGATQQILDEADRSLHDALCVLAATVKESIIFGGGCSEALMATAVLKETPGKEAIAIEAFARKSLKSTSYAGDGS........................................................................................... 433

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.