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Query: gi|16128009|ref|NP_414556.1| chaperone Hsp40, co-chaperone with DnaK (dnaJ b0015 exp) [Escherichia coli str. K-12 substr. MG1655], from E.coli

Results of FFAS03 search in SCOP175
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLNERQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTRLast
1 -47.300d1xbla_ a.2.3.1 (A:) DnaJ chaperone, N-terminal (J) domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  100  1.AKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQ............................................................................................................................................................................................................................................................................................................ 75
2 -43.500d1wjza_ a.2.3.1 (A:) CSL-type zinc finger-containing protein 3 (J-domain protein DjC7, 1700030a21RIK) {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  30  13TLKKDWYSILGADPSANMSDLKQKYQKLILLYHPDKQSADEECMQKFIEIDQAWKILGNEETKKKYDLQRSGPSSG............................................................................................................................................................................................................................................................................................................ 94
3 -40.800d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  100  1..................................................................................................................................GVTKEIRIPTLEECDVCHGSGAKPGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERS....................................................................................................................................................................... 79
4 -38.400d1iura_ a.2.3.1 (A:) Hypothetical protein KIAA0730 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  25  13SILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDANEVFKHLQNEINRL---EKQAFLDQNADRASRRT........................................................................................................................................................................................................................................................................................................... 87
5 -37.800d1gh6a_ a.2.3.1 (A:) Large T antigen, the N-terminal J domain {Simian virus 40, Sv40 [TaxId: 10633]}  ali model 3D-neighbors follow..  18  6.ESLQLMDLLGLERSAWGNLMRKAYLKKCKEFHPDKGG----DEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDENAFNEENLFCSEEMPSSDDEAT............................................................................................................................................................................................................................................................................. 114
6 -31.000d1fafa_ a.2.3.1 (A:) Large T antigen, the N-terminal J domain {Murine polyomavirus [TaxId: 10634]}  ali model 3D-neighbors follow..  17  9.DKERLLELLKLPRQLWGDFMQQAYKQQSLLLHPDKGGS----HALMQELNSLWGTFKTEVYNLRMNLGGTGF............................................................................................................................................................................................................................................................................................................... 78
7 -30.200d1c3ga2 b.4.1.1 (A:260-349) Heat shock protein 40 Sis1 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  27  2...............................................................................................................................................................................................................................................................FKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRLPLSRVQPVQPSQTSTYPGQGMPTPKNPSRGNLIVKYKVDYPISLNDAQKRAID.................................. 90
8 -29.200d1m1qa_ a.138.1.3 (A:) Flavocytochrome c3 (respiratory fumarate reductase), N-terminal domain {Shewanella oneidensis [TaxId: 70863]}  ali model 3D-neighbors follow..  20  2...................................................................................................................................QKLSDFHAESGGCESCHKDGTPSADGAAQCQSCHGKLSEHKPHDGNLVCADCHAVHDMNVGQKPTCESCHDDGRTSASVLKK................................................................................................................................................................... 90
9 -27.000d1nz6a_ a.2.3.1 (A:) Auxilin J-domain {Cow (Bos taurus) [TaxId: 9913]}  ali model 3D-neighbors follow..  19  30WAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYAKMIFMELNDAWSEFENQGQKPLY...................................................................................................................................................................................................................................................................................................................... 98
10 -25.800d1nlta3 g.54.1.1 (A:139-212) Mitochondrial protein import protein mas5 (Hsp40, Ydj1), insert domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  33  1...........................................................................................................................................KQILCKECEGRGGKKGA-VKKCTSCNGQGIKQMGPMIQRFQTECDVCHGTGDIIKDRCKSCNGKKVENE........................................................................................................................................................................ 74
11 -25.400d1qo8a1 a.138.1.3 (A:2-102) Flavocytochrome c3 (respiratory fumarate reductase), N-terminal domain {Shewanella frigidimarina [TaxId: 56812]}  ali model 3D-neighbors follow..  20  10...........................................................................................................................................DMGSCQSCHAKPIKVTDSEAQCKSCHGEYAELAPHNSHLGDINCTSCHKGHEEPKFYCNECHSFD-IKPMPFSDAKKKKSWD........................................................................................................................................................... 101
12 -24.100d1fpoa1 a.2.3.1 (A:1-76) HSC20 (HSCB), N-terminal (J) domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  24  2....DYFTLFGLPAQLDTQALSLRFQDLQRQYHPDKFASGSQAVQQSATINQAWQTLRHPLMRAEY...................................................................................................................................................................................................................................................................................................................... 70
13 -23.300d1y0pa1 a.138.1.3 (A:1-102) Flavocytochrome c3 (respiratory fumarate reductase), N-terminal domain {Shewanella frigidimarina [TaxId: 56812]}  ali model 3D-neighbors follow..  18  9..........................................................................................................................................VQNQECDSCHTPDGELSNDSTQCVSCHGTLAEVAETTKFPGEVACTSCHSAHEKSMVYCDSCH---------SFDFNMPYAKKWLRD....................................................................................................................................................... 101
14 -21.300d1nlta2 b.4.1.1 (A:258-337) Mitochondrial protein import protein mas5 (Hsp40, Ydj1), C-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  26  2...............................................................................................................................................................................................................................................................FKRDGDDLVYEAEIDLLTAIAGGEFALEHVSGDLKVGIVPGIAPGMRKVIEGKGMPIPKYGGYGNLIIKFTIKDPE............................................. 80
15 -21.000d1nlta1 b.4.1.1 (A:110-138,A:213-257) Mitochondrial protein import protein mas5 (Hsp40, Ydj1), C-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  18  3.................................................................................................................................................................................RGKDIKHEISASLE---ELYKGRTAKLALNXRKILEVHVEPGMKDGQRIVFKGEADQA-PDVIPGDVVFIVSERPHK.......................................................................................................................... 75
16 -20.300d1c3ga1 b.4.1.1 (A:180-259) Heat shock protein 40 Sis1 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  19  13.......................................................................................................................................................................................DLFVGKKKSFKIGRKGPHGAS---EKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHP.......................................................................................................................... 80
17 -18.700d3caoa_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio africanus [TaxId: 873]}  ali model 3D-neighbors follow..  22  16...........................................................................................................................ERPAAVFNHDEHNEKAGIESCNACHHVWVNGDSVGTPCSDCHALEQDGDTPGLQAYHQQCWGCHEKQAKGPVMCGECHVK............................................................................................................................................................................. 102
18 -14.600d1gyoa_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio gigas, di-tetraheme cytochrome c3 [TaxId: 879]}  ali model 3D-neighbors follow..  17  2...................................................................................................................DVPCKVVITAPEGEDPHPRFGKVERNVSCVSCHHMFDG-CGDFQKCADCHIDRDDRSYERGFESEISCRGCHKAMKAKNEQLQGCHEA............................................................................................................................................................................. 106
19 -14.100d2cy3a_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio desulfuricans, different strains [TaxId: 876]}  ali model 3D-neighbors follow..  26  37........................................................................................................................................TKHATVECVQCHHTLEADGGAVKTTSGCHDSLEFRDKANAKAFHTQCIDCHKALKKDKKPCGKCHTT............................................................................................................................................................................. 117
20 -12.100d1i77a_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio desulfuricans, different strains [TaxId: 876]}  ali model 3D-neighbors follow..  18  1..................................................................................................................APAAPDKPLEFKGSQKTVMFPHAVHAKVECVTCHHQVDKESFAKCGSSGCHDDLAGKQGEKSLLKHTNCIGCHSK-DLTACAKSKCH............................................................................................................................................................................... 106
21 -11.500d1ft5a_ a.138.1.3 (A:) Cytochrome c554 {Nitrosomonas europaea [TaxId: 915]}  ali model 3D-neighbors follow..  25  1.....................................................................................................................................ADAPFEGRKKCSSCHKAPAKDYTQDKDCVGCHVDGFGQKGGYTIESPKGCESCHGPGRN-EERCSACHLNYEGSPWKGAK................................................................................................................................................................... 150
22 -11.300d1aqea_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio desulfuricans, different strains [TaxId: 876]}  ali model 3D-neighbors follow..  16  30........................................................................................................................................ASHMDIACQQCHHTPDTYTIESCMTEGCHDNIKERTEISSVDSEKSCVGCHRELKRQGPSCNSCHVQ............................................................................................................................................................................. 110
23 -10.400d1ofwa_ a.138.1.1 (A:) Nine-heme cytochrome c {Desulfovibrio desulfuricans, ATCC 27774 [TaxId: 876]}  ali model 3D-neighbors follow..  22  223.............................................................................................................................................ILCATCHHR-SPLSLTPPKCGSCHTKEIDKANPGR-AYHLQCMGCHDVARPRDTDCTTCHKA............................................................................................................................................................................. 290
24 -9.410d1os6a_ a.138.1.1 (A:) Cytochrome c7 (cytochrome c551.5, PpcA) {Geobacter sulfurreducens, PpcA [TaxId: 35554]}  ali model 3D-neighbors follow..  21  22...........................................................................................................................................................KAVPDCKKCHEKGKIEGFGKEMAHGKGCKGCHEEMKKGPTKCGECH............................................................................................................................................................................... 69
25 -9.300d2cvca1 a.138.1.1 (A:40-544) 16-heme cytochrome c HmcA {Desulfovibrio vulgaris [TaxId: 881]}  ali model 3D-neighbors follow..  24  433..........................................................................................................................................EKGTLCQGCHHN-SPASLTPPKCASCHGKPFDADRGDR-AYHQQCMGCHKIEKPANTACVDCHKE............................................................................................................................................................................. 503
26 -9.110d1j0pa_ a.138.1.1 (A:) Cytochrome c3 {Desulfovibrio vulgaris [TaxId: 881]}  ali model 3D-neighbors follow..  18  24........................................................................................................................................STHKAVKCGDCHHPNGKEDLQKCATAGCHDNMDKKDKSAK-TKFKSCVGCHLETAGADAAGSKCH............................................................................................................................................................................... 107
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alonso A, Rahmouni S, Williams S, van Stipdonk M, Jaroszewski L, Godzik A, Abraham RT, Schoenberger SP, Mustelin T. Tyrosine phosphorylation of VHR phosphatase by ZAP-70. Nat Immunol. 2003 Jan;4(1):44-8. Epub 2002 Nov 25.