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Query: IDP00019 gene: pykA-2; pyruvate kinase BA_4843 [Bacillus anthracis str. Ames], from CSGID

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRKTKIVCTIGPASESIEKLEQLIEAGMNVARLNFSHGSHEEHGARIKNIREASKKTGKTVGILLDTKGPEIRTHDFVDGQAELVTGAEVVLSTEQVLGTAEKFSVSYAGLYDDVDPGSRILIDDGLIELEVIEKADGNIRTKVLNSGTVKNKKGVNVPNVSIKLPGITEKDVKDIIFGIEQKVDFIAASFVRKAADVLEIRELLEEHNAQYIQIVPKIENQEGIDNIDSILEVSDGLMVARGDMGVEIPPEEVPLVQKRLIKKCNVLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGQYPVEAVTMMANIAVRVEKSLQYEDMFKKRIKEFTPTITDAISQSVAHTALALDVAAIVAPTESGYTAKMISKYRPKSPIVAVTSDEQVGRRLALVWGVQAFMAEKRAASTDEMLDTAIQTGMDAGLIGLGDTVVITAGVPVAETGTTNLMKIHVVGEEVAKGQGIGRKAAKGKVVVAKTAAEAVANVNEGDILVTTSTDKDMIPAIEKAAALVVEEGGLTSHAAVVGVSIGIPVIVGVNGVTATLKNGQEVTVDAARGIVYNGHAEVLLast
1 -107.000PF00224.19; KPYK_EMENI/32-379; Pyruvate kinase, barrel domain  ali follow..  48  1FRRTSIICTIGPKTNSVEKINALRRAGLNVVRMNFSHGSYEYHQSVIDHAREAKQQAGRPVAIALDTKGPEIRTGNTVGDKIPIKAGHEMNISTDETASDDQNMYVDYKNITKVISAGKLIYVDDGILSFEVLEVDDKTLRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDISDLKFGVKNKVDMVFASFIRRGSDIRHIREVLGEEGR-EIQIIAKIENQQGVNNFDEILEETDGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSDVANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNVF.................................................................................................................................................................................................................................................. 348
2 -46.800PF02887.14; D5C1C2_NITHN/363-477; Pyruvate kinase, alpha/beta domain  ali follow..  28  1...................................................................................................................................................................................................................................................................................................................................................................EGIAMAAMYLANHFDIKAIAALTESGSTPLWMSRISSAIPIYALTRHVETRRKVTLYRGVCPVSFDVNSSDHALINSEAISELQRRGAVRDGDWVIITKGDLTGVQGGTNALKV.................................................................................................................... 114
3 -14.400PF00391.21; I4BU05_ANAMD/423-506; PEP-utilising enzyme, mobile domain  ali follow..  40  6............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ILVRPETTPEDIHGLSMAAGLLTSRGGQTSHAALVARSLGIPCVVGCEAVNVAVKKDDVITIDGTSG.......... 84
4 -9.670PF03328.12; Q8ZRY2_SALTY/5-223; HpcH/HpaI aldolase/citrate lyase family  ali follow..  16  23......................................................................................................................DAVMFDEDAVALREKDTARLLVHHALQHPFYQDVEKVVRINPLN------TPFGLADLEAVVRGGADIVRLPKTDSKNDVLELEAQVERIERESTRLMAAIESAKGVVNAVDIATSSPAIALAAFDYVMDMGTSELFYARCAVLHAARVAG---IAAYDVVWSDINNEEGFLKEVQLAKGLGFNGKSLV...................................................................................................................................................................................................................................................................................... 217
5 -6.790PF13698.4; W0I276_9ENTR/27-121; Domain of unknown function (DUF4156 topsan)  ali follow..  15  7..........................................................................................................................................................................................................................................................GQSVRFTDTQPGSECRLLGELTGTQSNWFSGQNGENSAMRGAANDLRNAAAMGGNVIYGATSPVSKKETYLASFVPLDSKIQGQ........................................................................................................................................................................................................................................................... 91
6 -5.990PF10249.7; F4WA36_ACREC/20-144; NADH-ubiquinone oxidoreductase subunit 10  ali follow..  18  28...................................................................................................................................................................RVPTIDECYTDDLVCYTEADCQFKRDKAVED-----QILFILRSR-------FEQCAIYHGEDVKKTYEDAAVAWFMKYGEMGVGLNAKNAYMKQKHRM................................................................................................................................................................................................................................................................................................................................... 120
7 -5.680PF14626.4; Q9NA28_CAEEL/261-384; Zc3h12a-like Ribonuclease NYN domain  ali follow..  11  2......................................................................................................................................................EPELNLPVKPLTDIILLFLIRGHKTTVYLPKYYQEFLSDCGVSKVDDLVAFQKLIDL----GFIKFLEITNPFNFKWFNVVADLAGAVFVSSEDYRQRKMKINYSKPSGRIIT.................................................................................................................................................................................................................................................................................................................................. 113
8 -5.330PF00920.19; B8FFW7_DESAA/38-544; Dehydratase family  ali follow..  15  30......................................................................................................................................................................GVHAAGGLPFEFNVPAPCDGITEGHEGMRYVLAQ-RDLI----ADMIETHVRSMRYDGIVFIAGCDKIIPGMLMAAARLDLPSIFLTGGPNSWSIRHTPQMNGS--YDDLEAKMSCATAATCGACEVMGTANTFQCIAEALGMT-PAFLSEKLTFARKTGMRIVSLVEEGVNARQVLNQKSLLNAVMVDLAIGGSTNST---LHLPALARAMELELPLETFNEYSAKIPTLTAPNGPHGIIDLYMAGGVQGVMKVLEHDLNTDAMTVVGGPLKDAFAAVKDAAVIRPKDNPYLAEGGTAALFGSLAPESVIKQSAVIESMRTGKARVFESEHDALKTIREGDVVVIRNEGPETLAVTMGLDMAGYKQVALITDGRFSGATSGPCI-AAAGGPIALVEDGDEISIDIPARKL........ 465
9 -5.260PF03520.12; Q0P4Q9_XENTR/368-556; KCNQ voltage-gated potassium channel  ali follow..  12  80.........................................................................................................................................................................................LVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQ--GRVDQIIVPVEKKPRDKGEKVSTMGPEVEAADELSMMGRVVKVERQVQSIEDKLDILLG............................................................................................................................................................................................................................................................................................................. 180
10 -5.060PF00742.17; R5EAW4_9BURK/138-316; Homoserine dehydrogenase  ali follow..  16  1..............................................................................................................................................................PIVKALREGLAANRVSSIAGIINGTCNFILSTMRDTGRSFDDVLKEAQRLGYAEADPTFDIEGTDSAHKLMLLSAIAFGVPVDMTKVHIE-----ITHLEAKDIKFAEELGKLLGITKYTDYGIELRVHPA-ANVEGAMNAVVDAAESSLYYGKGAGSEPTGSAV...................................................................................................................................................................................................................................................................... 174

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Rychlewski L, Zhang B, Godzik A. Fold prediction by a hierarchy of sequence, threading, and modeling methods. Protein Sci. 1998 Jun;7(6):1431-40.