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Query: [E] COG4820 Ethanolamine utilization protein, possible chaperonin, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSMVVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPPGTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVTYSADEATGGHHISLTFAGNRRISLEEAEQYKRGHGEEIWPTVKPVYEKMADIVARHIEGQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLYAKLast
1 -112.000[E] COG4820 Ethanolamine utilization protein, possible chaperonin  ali  100  1MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSMVVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPPGTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVTYSADEATGGHHISLTFAGNRRISLEEAEQYKRGHGEEIWPTVKPVYEKMADIVARHIEGQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLYAK 278
2 -48.200[D] COG0849 Actin-like ATPase involved in cell division  ali follow..  12  88........IQSWNDSGAAPIADTEVTQEDIDAALHTASSI-----------KMPEGLVVLHRLPQEYAVDQQKNIKNPLGFQGG------RLTSNVHLIACHQDWLNNLRQAVERCKLKIDKVIFSGIATSHSVLTEDVCLIDFGAGTMEVMVYTNGALRFSKVIPYAGNRVTDDIAYDLTTSRVEAENIKVKYGSALSNVTAGRYREILELVKEELIQLKIAGIVITGGGAQIKDLKECATDVFGHVRIGNPKKPQYSTVLGLLQYEYSSNDE.... 394
3 -33.400[NU] COG4972 Tfp pilus assembly protein, ATPase PilM  ali follow..  14  53.LVNIDAVGSALKRAIAKAGIRSKDAVLAIPASLTESQTVSLPDNLTEDELFVQVESEANRLFPQNVNFDY-----------VVIGPSETEGGIGVRVMATVAERVTERVTAAEMAGLRPIVMDVEENAIQRAMTHPVVAMFHLGGANSQALFYQGWKELYEQPLSGSGDQLTQSISRLFSLDLLKAEVKKRKNTEYRSQLLKPSLETLAMEVSQAIQVGRVDEIVLSGGHASLLGVQTAIQQQTQNTTLANPDLPAYIVSAGLALRGLQ........ 356
4 -26.200[D] COG1077 Actin-like ATPase involved in cell morphogenesis  ali follow..  21  12..............................GMAIDLGTANTIVYQKNCGIV-TPTDIEAKRPLKDGVIADFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPRAIQEAAESAGGRDVYLIEEPMAAAPVTEATGSMIVDIGGGTTEVAVLSLGGIVYARSVRVGGDKMDEAIISNLLIGEATAEKIKQEIGRQIADSLIEPVSQIVEAVKVALEATPPEGIVLTGGGSLLRNLDFVLSEA-TKLPVIVADDALSCVALG............... 327
5 -17.900[O] KOG0101 Molecular chaperones HSP70/HSC70, HSP70 superfamily  ali follow..  21  120.........................................................................SSMVLTKMKEIAEAYLGYPVTNAVITVPADSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDNVLIFDLGGGTFDVSILTIDDGIFAGDTHLGGEDFDNRLVNHFVEEFKACERAKRTLSSSTQASLEARFEELCSDLFRSLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQA.......... 377
6 -17.800[O] COG0443 Molecular chaperone  ali follow..  21  5...............................LGIDLGTTNSCMAVMEGGDAVVLPNAEGSRTTPSVVGFSKKGSAMILQKLKTEAEAYLGETIKQAVITVPADAQRQATKDAGSIAGLEVLRIINEPTAASLAYGLDKILVYDLGGGTFDVSILELGGGVFSGDTHLGGDDFDQRVIDHLLAEFDAAEKAKIELSGVTVTNIRAQFQKMTEDLLEKLTPNDLDKVILVGGATRMPAVVELVENFT-GKKPYKNINPDEAVAIGAAIQA.......... 353
7 -17.200[O] KOG0100 Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily  ali follow..  23  152.........................................................................SAMILTKMKETAEAYLGKKIKDAVVTVPADAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDNILVFDLGGGTFDVSVLTIDNGVFNGDTHLGGEDFDHRIMEYFIKLIKECERAKRALSSQHQVRVEARFEELNNDLFRKLQKSQIDEIVLVGGSTRIPKVQQLLKDFFEGKEPNKGVNPDEAVAYGAAVQG.......... 408
8 -17.200[Z] KOG0797 Actin-related protein  ali follow..  17  188...................................FGEEALKISPKEPYCLYHPIRRGHFNVSPHYSAQRVCEDLTAI--LLEKLHITHKERFSFHAVIVVPETIKEMLTIVLGELYFNSAVVHQEGLSAVFGNGLTTACIVNIGAQTSTVVCVEDGVSLPNTEKPFGGEDICRCLLWIQRIDMLMLNQLKESFKEEKIGLAEAITSSILSAGRIDLRRKLFSSIQLIGGAGLTKGLVAAVEERVLHQVLPSRTEPQFVTWKGGAILGI......... 553
9 -16.300[O] KOG0102 Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily  ali follow..  23  164.........................................................................GGFILSKMRETASTYLGKDVKNAVVTVPADSQRQATKAAGAIAGLNVLRVVNEPTAAALAYGLDKVAVFDLGGGTFDISILELNNGVFNGDTHLGGEDFDVALVRHIVETFEAAEKAKCELSSLSMEISRAQFEKLVDPLVRRLQTSEINEVILVGGMTRMPRVVETVKSIF-KREPAKSVNPDEAVAIGAAIQG.......... 422
10 -15.900[KG] COG1548 Predicted transcriptional regulator/sugar kinase  ali follow..  14  44...............................LGIDIGGANLKVASKDGWEIIYFPMWREAERLEGKLIAEKYSTAKAGVVMTAELADFFKSRAEGVEFIAKACKKAFEDVRFLDVEGKSDIDNPENFAASNLEEAYRNFLFVDMGSTTTDIIPVTSKIEAAKTDIYFGVEECMRRLARTVCSDLEELGEEKVK--ELALEAKWAMIDRLSEVIEHKSKIYGLKTVFACGGEFLIAEACEEAGAECRLISELYGDYSKLFPAYAMLKLVEQH....... 355
11 -14.600[O] KOG0104 Molecular chaperones GRP170/SIL1, HSP70 superfamily  ali follow..  17  132...............................................................GESYTVEALTAMILANAKKFTEEYAQAAEIKDVVITVPVPAERLAVERAAQMAGLTVLQLINDGTAAALSHGIQRLMVYDMGAAKTTATIVKQPKMTVLGDRTLGGIEMTNRLRDHLIEMFKEAERLKQ-TREDFNHLISDMESRFGEPIEQALRMAQIDQFVLMGAGTRVPKVQEIVQKTIGTKEIGKFLNTDEAVAMGALFQAAHLSKGFKVK 422
12 -14.300[O] KOG0103 Molecular chaperones HSP105/HSP110/SSE1, HSP70 superfamily  ali follow..  16  124...............................................................................NLKGIAEKNLNTAVVDCCIGIPVDLQRRAVLDAATIAGLHPLRLIHETTATALAYGILNVAFIDIGHASMQVCIFKKGQLKILSDRSLGGRDFDEVLFNHFAAKFKDCEKLKKVLSEEFEEISIPILERVKRPLEKALSDAGVHMVEVIGSGSRVPAMIKILTEFF-GKEPRRTMNASECVSRGCALQC.......... 377
13 -14.100[E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition  ali follow..  17  7.............................LSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRNARPAVMSAGPHLESVIAGHGAGAQTLSEQRLCRVDIGGGTANYALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTAQLVQVTRRMAELIVEVIDGTTPEIITLSGGVGCFADIGPLLATALHEMNVQFPAQTVRATVIGAGAHTLS........ 321
14 -10.400[Z] KOG0680 Actin-related protein - Arp6p  ali follow..  11  8...............................IVLDNGAYHIKAGFAGGKVVEIPTTLQFRRAHEKGYLVHWSTETAVWDLVMRNVGVMEPSMADYSLLLTQPVFTMPSIEHNTIQLVFEEFQFDAYLPCTPAELIPECVLVIDSGYSFTHIIPVIDFSVQEQAVVDVGGKLLTNYLKEVISVSQNFKEDMEICHEKPRSKLIPEAVMQSVTHFPENIQAMLLENVVTIGGNCKFPGFHKRLSSELRSVKVFEPSDPICFPWKKASHMPLEHWNA.... 379
15 -10.100[I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)  ali follow..  10  2..........................TQIYKTGIDVGSTTVKLVVFDENF----------KLIFSRYERHFSDVKAATIKVFKDFIEEYGDLNLELAITGSGGMGLA------EVIDVPFVQEVIASSITIEKFIPQTDVMIELGGEDAKMTFFDNGELRMNGTCAGGTGAFIDQMAALLKVDANGVNELAKNYKTDVQPLLNVRREDIAASIFQAVVNQTIAGVAFLGGPFFMSELRKRFIETLKEENIIFPENPQLFVAMGAALYEETSQK..... 263
16 -9.610[Z] KOG0679 Actin-related protein - Arp4p/Act3p  ali follow..  11  77......................................................DGAEVMSPLKNGMIEDW-ECFRAILDHTYSKHVKSEPNLHPVLMSEAPWNTRAKREKLTEQYNIPAFFLCKTAVLTAFANGRSTGLVLDSGATHTTAIPVHDGYVLQQGIVPLAGDFISMQCRELFQWHNYMCNEVIQDFQASVLQVVGHVVTTSIGMCDIDIRPGLYGSVIVTGGNTLLQGFTDRLNRELSQLKLIASNSTMFSPWIG............... 393
17 -9.210[H] COG5146 Pantothenate kinase, acetyl-CoA regulated  ali follow..  61..............................HIAVDIGGSLAKVMYYVCESSSPSSSSSSISEAEN--TAKIEDCIQFMANLIDNHVKNCNKKKITLIATGGGAYKFYDRMSKQLDIKVIREDEMECLIMGLNYFVSCPHMLVNIGSGVSILKVTGPSQFERIGGSSLGGGTLSTTIASSFGKVFRERKPLEEFAPQDISSLLLAISNNIGQIAYLHAQKHNVQNIYFGGSFIR-VQTMHTLTYAIQTMNAYFLRHEGYLGVFGAFMKYATSQPS.... 395

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Li W, Jaroszewski L, Godzik A. Sequence clustering strategies improve remote homology recognitions while reducing search times. Protein Eng. 2002 Aug;15(8):643-9.