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Query: [A] KOG2548 SWAP mRNA splicing regulator, from COG0516

Results of FFAS03 search in PfamA30U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MWHEARKQERKIRGLIVDYRKRAERRQYFYDKIQADPTQFLQLHGRRSKIYLDPAVAAAGDGAAIMQGQQDNLIDRFDVRAHLDHIPPVNKTNAEGADGDSELTLEERQLNYERYRILAQNDFLNVSEDKFLHQLYLEEQFGANAQLEAERNLAKKKQKTGGATIGYSYEDTGDGATIGPQPFGAASSTVIGGAAAVAKGEKGDGSEESDSDIDMDVSIDIGKLDTSQAHELNACGRNYGMKSNDFFSHLTKDADEADALRIAREEEQEKMLLSGRKSRRERRAQKERRIANRPFSPPSYAAKEDKDKKGGGKGGEKEKEEDSESRSPSPAEAGPEKITYITSFGGEDEMQPHSKITISLTKPGLTLGESCINASSGAAIAAAAASSVSYAQKVKDNLDKLKVMNESSKRNRRRSRSHSRSRSRSATVSRSRSGSRRSGSRRRSRRSRSYHRRSRTRSRRRRRYYSRSRSRSRSRSRSLSRSRSRSRSRSRSGSWKRYKARSPSYKRSRKRYSYSSRSSSGSSYRRRSRSRSPSNRRSRVKKKTTPPPVATVGGYCLNTTTTTTTSTVTAVKMFQQQQQQPPAKATPPMISYPIPARMLNVNQALTATAPVAVQPQVVEPPPPPLKRYYGRKRGNDTSSSSSSGAENSEGSDNEEQQQPQLGKRAEDSDDMELDTASERSHALQPTMSSSSSTGNQTGKYSSATETGSGHPSSGGGGRPNLRERLKRKMQNLLNRQYKADKRAEIEKTERERLQQQEREDEMRELALKLRRRRRELRHKYGTPSSGKLSDSDAESVASESQLAKSSTRRSRSRSESRRRSPPPETQHSRRSSSRTERRRRTRTPSPKYNRRQRSRSRSGSRVERKRRSHSRRRSGSRDRRRSRSRRSQSRRRRQRDRSIERNREREQYRQQHQQQNERLRGRDRDREADYGHGGSGSSNRGRVVISAPPKLKKLVDYLast
1 -47.900PF09750.7; K7EM61_HUMAN/21-151; Alternative splicing regulator  ali follow..  46  1.......................................FLQVHGRACKVHLDSAVALAAESMMPWQGDTNNMIDRFDVRAHLDHIPDYTPP--LLTTISPEQESDERKCNYERYRGLVQNDFAGISEEQCLYQIYIDELYGGL---QRPSEDEKKKLAEKKASIGYTYEDS................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 131
2 -9.160PF13779.4; D7A9C0_STAND/55-942; Domain of unknown function (DUF4175 topsan)  ali follow..  424.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DEAGNIGRSRPRTFVLPERSFSNPLARALIDERRVLAFDANQRERVEAGLDALAIAPEKFTPDPSHYMGLRSAYWRLANAKSDEDLRGVVAYLWEIAVRIEDGDLSDVEKKLRDAQQALQNALENNASDDEIKRLTQELREAMQEFMQALAEEAQRNAQADSDQPMGPNTRMVRPQDLQKMLDRIEDMARNGARDAARQMLSELQNMLNGLQAGRQQQRRQGQNQMSQAMDQLGDMIRRQQQLRDRTFKQGREQGQQGEQGQQGQQDQRFGDLKQSQEQLREQLRQLREKMQQAMRGRQQGQGEQGQQGQGEQQGQNGQGQQGQQGEGQQGQGMPGEGGLGEAEQAMREAEQALGQGDGTGAVDAQSEALQALRKGAQQMAEAMQQQPGQGQGQEPGGPSGETAERNDPLGRPMRSRDYGDDVTVKVPDEIDMQRARR-EELRRRFGEPERPRLELDYLERLLR.... 888
3 -8.310PF17076.3; SBE22_CANGA/1-813; SBE2, cell-wall formation  ali follow..  13...............................................................................................................................................................................................................................................................................................................................EEPSVESKSGRTLAGITSSRKESGMRSRTSSGSAQAVGLGLGRRPSDNLFHGHADPLDTMQMLSEALPQPPKIEHGMRRERPISNDSIMTTKSSEIFSTSSSDTQSNISVATNDSEDHSFGMDKSVDNSSTNATLTNRSIENRSNGDSYSIGEKSDVSVNRSTKSGNNPLQRTQSETISVNMSHNRSMNGAMKQPTPPFMGKNSSIPNLRYNSQPQQDNRSVPNGEFGSKLYNLSNSTSAIIPNAGTGSKLALTPSQRYRLRKEQSEHALRDVIKRKEKLYDEQDGIIELQEGDIDGSFIFNVPMSSYSTTSFLNTTRQKDSATNSSSTITERITPGENQSQNNRESNMSFASTISSTSMLDFFEMPTSPIPGVNKVSDFQYLQDTTKHLSSVYLHSSTKLSKSKLSERTASALPLEFKEASEKGMEDLLLVSENKLDAVSHTRPSWLPPKDPEEKKLHEREISKTLSMASLDQLEKNKDRDSKIIKDETNKQK................................................................................................................................................ 508
4 -7.850PF09043.9; F7V920_CLOSS/4-511; D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit  ali follow..  12  106.LHPEEEIRAAVQPVTERIAANVKKRNDYLDSFGDKEGPYLYLIVATGNIYEDITQAVAA----AKQGADIIAVIRTTGQSLLDYVPYATQENFRLMREALDKVGEERYIRLCNYSGLCMPEIAAMGAMERLDVMLNDALYGILFRDINMQRT-SRVINGYAGVIINTGEDNYLTTADAIEEAHTVLASQFLNEQFALEAGLPPQQQGLGHAFEMSPEVE--LLELAQAQMAREIFPDAPLKYMPPTKFMTGNIFRG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 381
5 -7.770PF15712.3; M3Y3S4_MUSPF/713-1384; NPAT C terminus  ali follow..  234................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KSQKTQGLKNKPCTGKQANNLVDSSSHLIGCHVQRTEVSDKNMATDFGKKLEEITVPFSLESIVPTSKPFESHRRVLCFDGITSPVANTQGTNHKVASQNKERNDISFPNLESPLVSSTLKPPSNNALKRERERPPLPKILSKSETANSRHTAIKETQLEKKASPTEIVLESFHKATANKENELCSDVERQKNPETSKLSNGQQNGGLRNEKTIASLQELTKKQGTSSNSKNAFSVGAPVKDPKQEQTKCASSVMNAPSKPTTDVLPDGQWPSPVAKLPESSDGPGPRTPGAGAGDRPKEEPRDGIKVPSSSTAK-PPVTPDLPACSPASETGSENSVSMAAHTLMILSRAAVARTASTTPLKDNTQQFRASSRSTAKKRKMEELDERERTSRASSKSLANSSLPMKKKKIKKKK.............................................................................. 650
6 -7.580PF12877.5; M3ZTY8_XIPMA/825-1517; Domain of unknown function (DUF3827 topsan)  ali follow..  292..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RTDKLEFQPDAMTTIQQRQKLQAPSVKGFDFAKLHLGQQSKDDVMVIQEPALPGSGSAPLAQSIKDGFSPSENGEVPTPKSKTSASSTKASRGGRRRERISPSDGDSVVSDHSSEREPTEENPRAHATPSDSKQTRKNRIGPPPMNGAANEQLSSASIFEHVDRMSRATDASRRLPNKVQLIAMQPMPVPPLHSQPVNGKPSDPNQMNKEIQAALRHKSEIEHHRNKIRLRAKRKGHYDAMDDMVGSLSDTKEQDRIYQKAQTQIDKILDPDNPVPAVFMDSKKSGRGRRSPKQRLKDQLNGGLIEADKDHLITEDSDAVYRKCPGVNNVAYVSDPDQGPGSPQRSPSPTDDVFLGPASSPPGHAPPPPPYLPPQ------------PSIEEARQQMHSLLD. 683
7 -7.520PF16933.3; H6NPM0_9BACL/1-460; Putative exopolysaccharide Exporter (EPS-E)  ali follow..  10  147IW-SAAKNYKIISNVLLGF---VVLLRTFPSKRMENPYGFLHYADKYPSLLAAGFSYNLGDKILIWLGPSGVTVEGYDNAVFLAYLTVVPSLVLFVVSVETR---------YDKYRKFYGY----ITNGGTLEMI--LAAKKRMVEVLWNEMLRMAKLQGSLTLFLIVVSGFLLESFGYGPLTADIFRIYSLGAMAGTLMLTV--EDRQGAWVTSLLFLSLNALFTLGVLPPGLDFYGFNYFLAAFIAFTYSAWRLLGFLQRIE..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 456
8 -7.280PF11725.6; Q887C9_PSESM/17-1794; Pathogenicity factor  ali follow..  10  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TVTPDARAATDLQERAEQPRQRSSHSLSSVGKRALKSVGKLFQKSKAPQQKAATPPTAKNVKTPPPASNVATPRNKARESGFSNSSPQNTHSAPKSILRNHPNQASSSGAQTHEIHPEAAPRKNLRVRFDLPQDRLERSPSYLDSDNPMTDEEAVANATRQFRSPDSHLQGSDGTRISMLATDPDQPSSSGSKIGDSDGPIPPREPMLWRSNGGRFELKDEKLVRNSEPQGSIQLDAKGKPDFSTFNT.................................................................................................................................................................................................................. 248
9 -7.200PF11992.6; Q1LH80_CUPMC/17-345; Domain of unknown function (DUF3488 topsan)  ali follow..  12  180LWRLPQSEPIGRTGI-------------------SDTMK-----GSIGKLIRSPDVAFRVVGEAPWRA---FVLWDYDGETRPARSRSVRPADGLRDDIGDSDFAGSAAPGAHEYNITLEP-----TQASWLYVLDRGQAISSSLNAQVSTDNEFFANLPVDRPLRYRARSV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 329
10 -6.870PF11847.6; V5X6I4_MYCNE/1-670; Domain of unknown function (DUF3367 topsan)  ali follow..  11  418.WHDTAA---------------------WLDEHNTDGGRVLVAPGAPFATQ-------------VWGNSHDEPLQVLGHSPWGDSIPLTPPETIRALDSVQRLFAAGRP----------SAGLADILAQQNISFVVVRND---LDPEASRSARPLLVHRVMDNSPGLTRVAEFGDPVGPGTLDGFVSDSGLRPRYPAVEIYRVDDAHPGPYVTDADTLARVD--GPEALLRIAERRRLAGQQPLG--MLLTADAQRA-------GLPTPLVTVTDTPVARETDYGRVDHHSSEMRAAGDLRHTFNRV.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 669

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A. XtalPred: a web server for prediction of protein crystallizability. Bioinformatics. 2007 Dec 15;23(24):3403-5. Epub 2007 Oct 5.