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Query: [S] KOG4683 Uncharacterized conserved protein, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAEIKVERSHDQHLLEPKEDTSSSYTRRSLAGNRPRLASLDIFRGLTVALMILVDDAGGDWPMIAHAPWNGCNLADFVMPFFLFIVGVSIALSLKRISNKFEACKKVGFRTCKLLFWGLLLQGGFSHAPDELTYGVDVTMMRFCGILQRIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGTYVPDWEFVVYDKDSVLYGKILSVSCGVRGKLNPPCNAVGYVDRQVLGINHMYHHPAWRRSKACTDDSPYEGAIRQDAPSWCRAPFEPEGILSSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLTLHFTHLMPLNKQLYSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFNGWYYRHPHNTLHVFIRVWHSRRVGVLMYVIFAEILFWGLVTGVFHRFKIYWKLLast
1 -155.000[S] KOG4683 Uncharacterized conserved protein  ali  100  1MAEIKVERSHDQHLLEPKEDTSSSYTRRSLAGNRPRLASLDIFRGLTVALMILVDDAGGDWPMIAHAPWNGCNLADFVMPFFLFIVGVSIALSLKRISNKFEACKKVGFRTCKLLFWGLLLQGGFSHAPDELTYGVDVTMMRFCGILQRIALSYLVVALVEIFTKDSHEENLSTGRIVAASVLVIYLATLYGTYVPDWEFVVYDKDSVLYGKILSVSCGVRGKLNPPCNAVGYVDRQVLGINHMYHHPAWRRSKACTDDSPYEGAIRQDAPSWCRAPFEPEGILSSISAILSTIIGVHFGHIILHLKGHSARLKHWISTGLVLLALGLTLHFTHLMPLNKQLYSFSYICVTSGAAALVFSSLYSLVDILEWKHMFLPLKWIGMNAMLVYVMGAEGILAAFFNGWYYRHPHNTLHVFIRVWHSRRVGVLMYVIFAEILFWGLVTGVFHRFKIYWKL 455
2 -104.000[S] COG4299 Uncharacterized conserved protein  ali follow..  24  1.............................MSQPAARFLSLDVFRGLTVFLMIVVNTAGPGYSQLVHAPWFGFTAADAVFPSFLFAVGCSMAFAFSKPIPLNDFTVKVLRRAALIFLLGFLMYWFPFVRKVGDWALIPFSDTRVMGVLQRIALCYLLAAFAVRWLSPRLIVALCAVLLLGYWAILMAFGD-------------------------------AAPLSKLGNAGTRLDLLLIGQNHLYRKDG---------------------------GFDPEGLLGTLPSTVNVLAGYLAARFLKENPGSSQAMGRMAIAGLVLILAGLVW--SPLFPIAKKLWTSSFVLLTVGIDLILLAGLAKLLEGKASNPGTYFFQVFGLNPLVLYLFSELFVVVLGMIEVAPGVGEWVGVNLFQAVMPGAFGSLLCALAYTLVCW-LLGYVMARRGVVVKL 372
3 -63.200[S] COG3503 Predicted membrane protein  ali follow..  14  2...........................PNSISNSSRLHSIDALRGLVMLFMLLDHVRETFVASTEPALFLSRTLAHLCAPVFVFLTGLSAFLYGEKHQGRRAVSAFLFKRGLFLVALELTLVNFAWTF-------QLPPTVIYLQVIWAIGLSMLALAALLWLPRP-------LLAALGVLLVAGHNLLDPLHFAPGSAWHLPWAVLHDRGWIEAG-----------------------------------------------------------DALRLRTSYPLLPWIGVIALGYAAGNWFSGATPATTRRRYLLAGGGGLLLGFILLTLMGFFNVTKYPPSLLFLALTLGIGLLLLAWFERL----DWSGRGKALVAFGGAPMFFYLLHLYLLKLLLLALAIWGANRGDYFGFSSVPALWLCSILLAVALYPAVHWFAGFKARRRDIAWLK. 382
4 -28.300[S] COG4645 Uncharacterized protein conserved in bacteria  ali follow..  11  3...............QKTFEGGNDQRGVAHPVPTGRDTRLDVFRALCLLTIFVNHVPGQYLEYLTHKNFGFSDSAEA----FVLISGLSVGAAYSGKFLAGALTLKIWRRALALYVAHIMTSVVTLAIFAGGALYFGRQELIGEINIRPIVEQTEQGIVAMVLLGHQLGYNNILSMYAVLFLLLPGFLWL---------------------------------NAVRPRLLFAFSATLWLAAGCFKMVPYNFL-------------------------DGYWFLNPWSWQFLFVIGILCMSHVRRGGSLPRSPWLLGISVAYLAISAFWVLFSWLTGFDKTFLSLTRLLHVLALAYILATV----FSRLTRVGSNHPLVMIGRHSLAVFIFGTILAMAGQV--------------LLLVTDRDRIIGTIFVIGGIGLHFAYAYYLEWLKE..... 375
5 -27.700[S] COG2311 Predicted membrane protein  ali follow..  13  2..................................ERNVTLDFVRGVAILGILLLN-GLPKAAYLNPAWYGAITPRDAWLTLFALLFGAGLQMLLPR------GRRWIQSRLTLLVLLGFIHGLLFWD-----------------DILLAYGLVGLIC-WRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRAWTPDASAILYEKYWKLHGGVEAISNRADGVGNSL----------------------------------------------LGAQYGWQLAGMMLIGAALMRWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQW-RWCAFLLQMPRELSAPFQAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLF------------LFMHFDRLELLAFVIPVWLANILFSVIWLRYFWLWRQLTLRA. 375
6 -22.900[G] COG3594 Fucose 4-O-acetylase and related acetyltransferases  ali follow..  12  2...............LDNIRAGAKGRGSCPAGTNNRDLSFDFAKGILITLVIIGHLLQYLIYQGTDAFW---PYFKSIYPLFMAISG----YLSSGAILRKSFTQGVGERAMQLLLPMLFWCTLIWTLKSAVIFPMKSLTDTLLDLIWAAFISFILIRVLTTFNRLSIWIISASAIAVAFAPITLSI-----------------------------------------------------------------------------------------------TPLLKYTYPFYCLGFLFAQPIGWQNGVIWRYKWIFVVLLSIAAFICFLGWGKETYAYNNLVLIHFSGSLAASAVAMQSMFQCWRLVYSTRVARFVAVQLGQSTLLLYLVQGAVFRLMDLIQFGEVWNLTT-----------RITFATVLGVAIVVIAMAIRSIARNLGYVSRI 355
7 -22.100[S] COG3274 Uncharacterized protein conserved in bacteria  ali follow..  10  1................................MTNKIDWIDNLRAVACIMVVMIHSTTYYVTRGAQVGELNWDIANVLVPLFFMISGYLF-------FGEKSAQKKHFMRIGLCLLFYSVIALIYISTLTPIDGWASLRNILQKPVFYAIIVVYLVSPLIKVKPVSGRYLAILILLLAVVANPQTSKFSLDDFRLLPANLY------------------------------------------------------------------------------------IYGDTFYYLLYALLGRAMGMLETQGRMISWGAALLFVVSVICIAISTEKQTRINGSFADTFYMYCSPLVFIAAVSLWVWFKNCL--NQHIAWLSGLARHSLAIYGFHALIIHFI--------------RTHHYDFTAYPVLDILYVFALTLGLSTLLSMGLQRIDRRRWV 329
8 -21.900[S] COG4763 Predicted membrane protein  ali follow..  12  2.................................KQKELWINQIKGLCICLVVIYHSVITFYPHMTTFQHPLSELAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQWLALSALNQWLAPERDLSNASLHGMITASTSLWYLYALIVYFVVCKIFSRLALPLFALFVLLSVAVNFVPTPWW------------------------------------------------------------------------------------------GMNSVIRNLPYYSLGAWFGATIMTCVKEVPLRRHLLMASLLAA---------LAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSNTIAIYTTHRILVEIFSLT-------------LLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL 334
9 -21.600[S] COG5062 Uncharacterized membrane protein  ali follow..  13  101.................RRKPGCCLTKKNENTFDRRIAGVTFYRSQMMLTCILAVDFTLFPRRYAKVETWGTSLMDLGVGSFMFSSGTV------AGRKNDIKKPNAFKNVLWNSFILLILGFARMFLTKSINYQEHVSEYGM-NFFFTLGFMALGVFFFRRSLKKVSYFNLATFITLLHHCLLVLTPFQKWALSAPRTNILAQ--------------------------------------------------------------------------NREGIASLPGYIAIYFYGMYTGSVVLADRPLMYKRFQRLLFPLCILLVLYLVSNFLSVGVSRRLANTPYVANVAFINMFFLTIYILIDAYPYGSRVPKLLEDANNNGLLVFLIANVL--------------TGVVNLSFDTLHSSNAKGLTIMTMYLFII-CYMAHWLAQHGIRFRL 459
10 -18.400[S] KOG0411 Uncharacterized membrane protein  ali follow..  87...............GNPSSYPKQSVDAPQDDEPYTSMAIDRTRFCVVIAIFASDPFYKENAKLGKSMGYGLKLMDIGVGSFVYNAGFF-------------STRADPQRKMKNALSSFFFGMLRYLSKELLKLDVDDREF---GVHLNFFLMLGVLNLASLVINTRANFLLGFGMCLTHELFLKFFGLEKLIYSSARSSIITS--------------------------------------------------------------------------NIEGITFLLPQMGMFLMAADISKVVFKKKNLS------IIILYNAFFVAVLSIARVYSTSCRRIHNLYFCMVIMLLHTTHGIV-FEVFSRTFKIRNLEMHRFISKYLLFILVWSNML--------------VTLNKLLSASKDMSRCSSHALCITYLVLVFYVPCAINSKVAGKLQV 420
11 -15.000[G] COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation  ali follow..  13  49......................................STDCIKGLSILVIILHHQPVGFMGIYTCLGHLAV-------SMFLFFSGYGLMVSKLKKKNYFKGFSKRLSKVYLPFVIINAITIILTSLIFGTKFNLKDIIFYLSGLVIAILVFYLCFYVCFKFLSTNLAQHILLFLTFVYFFAMIFMGFREWW---------------------------------------------------------------------------------------------YNTAFCFPLGVYAAINYDALTKFLEKHYVKTLIIALIAFTFFFFLAHM---------LPSAIMPLYQTIASIIFVYLVLLFLFKFRLSSKPLLFLGNIAYEIYLVHMKILVAFFSF-------------IGARGSYIVYLYLILVIIVAFCFNKLFNLNKNKK---VKL 355
12 -12.500[R] KOG3700 Predicted acyltransferase  ali follow..  259..........................GDIQNEAEGQVTSLNCIRTISTVWVILGHCAAMLILICTNPV-NAYFAVDT----FFFISAFLLSFLWFKQLQKQRKALIYVHRIARLSPAYYIAILFVTFVYIRMLRDM-YVISWYLATDLQLYLMSPILLLSFAIGGAVFGLFASVVALVASTAFNAYQIFFWYFPPTDYPLGPKDPRYNENERRYDVWNYYNPLIRCQIYIMGLVLGYFMRKVPKININPWVDRIMWVLSLGSMVFVVLVIQDYSSGDGWTPVQTALYRSYSKTALAKLILESVSEQVFKIIIQNKKNIFINYKYFSLFFFIFFSARKTSKNIYNCFSRVLWGFAMSWIVISTYYRKGLIRDFMSLSFWTPLARLSFCAYLVHWMVLGYFFGRNHSELYFSTLSYFFLDTVIPVTALSFVIAIFWSSMFEIPFAKI---EGLLLG. 734
13 -11.000[D] KOG3004 Meiotic chromosome segregation protein  ali follow..  11  16.DSVQKDPTVPNGLDGSVVDPTIADPTAITARKRRPQVKLTAEKGLPYVLKNAHKRI--------RISSKKNSYDNLLFPKAKFKDFMKICQTVGKTDPVLREYRVSLFR......................................................................................................................................................................................................................................................................................................................................................... 134
14 -10.000[S] COG4292 Predicted membrane protein  ali follow..  44..SRESLYISACHPYEGSMAENHTHWLRKENTDQTKASFPELF--FDLVFVFALIQLSESL--SDDFSLGIAAEAVLFI-FALWWVWIHTTW-VMDLLDTEIEPVRLLLFTLMFFGIVMAIAL--------EAFKGMGLLFAVAYSAMQVSRSLFALYAFRRGDPASFMTFFRITAWLTISSTF------------------------------------------------WITGGLSEPHLRVVLWIVALVVEYTGPTVRYWVPLIGASPRETLDIDGEHLAERSALFVIIALGETILTIGKHTFSNLETEGTPWVLCFSFLTTVLMWWI-----TAQYLFTYGHLPIVGGIIFTAVGEDFSLAHPYQLGTYNFALAQLG--GPILFLAGTMWMKRVSSRVLPYSHVFGISLLTASFTLVPFVANFAIQALTGVILLVVAVWEYVALK..... 444
15 -9.460[I] COG1835 Predicted acyltransferases  ali follow..  11  6......................................DIDGLRAVAVLPVVLFHFGVSAIP-------GGFTGVDI----FFVISGYLISGSLLDDLERGQ-YWRRARRILPALTFVILLASIAAWFILLPSDLHEYSLSVIAASTFWSNIYFWKTTNYFSIDAELRPLLHTWSLSVEEQYYIFAPVL------------------------------------------------VYLIYRYASKRWLTILLPIAIGSFALAVMATTLAP-------TAGFYLLPTRIWELALGAMLMLRKPPALASRPLTELIGLAGFGLIAFGFVTISE-----SDPFPGYNALFPCIGTALLIYAGQPHADRPVPVATQVTPLVWIGLISYSLYLVHWPINSFVHYLSLK------------AIGVPTILAMIVASVALATFSWKYVEQPFRQKR..... 342

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.