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Query: [DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSGELQLSVNIPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDPEDEHTAVLTYYISTYVDLast
1 -96.500[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali  100  1MRFKTRISNLYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEVETIFEDYVVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTTWSGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFLRHVVDKYKSLSDRIIMSANMSGELQLSVNIPSARVSTKWKGLENPELDPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVLYVYITDPEDEHTAVLTYYISTYVD 287
2 -54.300[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  11  2..LELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSE-GFEHYRC----DRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAE---------YHSIVRMPS-NEFSRICKDLSSIGDTVVISVTKE-GVKFSTAGDIGTANIVLRQ---------NTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKV-----AEMGYIRYYLAPKIE 256
3 -40.500[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  9  2..FQAETVCLKQIQSTLRCID-FSKECTIEITSRGLRF-AVEESQSLQAHAFLDKS-LFQTFNFQGDSDDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIMHKRGVICKVQEMAGYATACELLTMECEDDVDINRLA-STLCTKIIMKS-NWLYDALVELDNNMGELIIHTSQKSTFLLRCVGALSTTEIEYPN--------------EKSVLESFETDSENTYSYRFSLIRHALKALQVGSKVNLRIDENGTLSIQIML-VGQEGLCTFVDFCIVPLDL 282
4 -32.900[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  12  1MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRS-MFEVYDMPP--HSDFYCKISMKGCLAVFRNMNEVEYCELNLLDNQTNLQVNLRCK------LETTKEATISIIDDQNINTN-----NTDQMPNIIRGDH-KLLTDISNNFNSSEEELTLEANSG-SVVAKNYIEGARVNDKFMRTQLK----------KPSEFEQYQVTKETVITFCIKEFRAFLLFAELNASLTLEFDEGMPFLLKI...................... 243
5 -6.290[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  8  136.....TMLQRTSFAVSREESRYVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTLDK-----------SFSGEYIIPIKAVEEIIKMCSDEGEAAIFLDQDK----IAVECDNTLLITK------------LLSGEFPDFSPVISTESNVKLDL-HREELITLLKQVALFTN------ESSHSVKFSFLPGELTLTA-----------NCTKVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSK-DELVSLGISDSYNPGI--------ITDSASGLFVIMPM.. 361
6 -5.990[K] COG1761 DNA-directed RNA polymerase, subunit L  ali follow..  11  1................MEVILDKRNEMEIVFEGETHTL-----CNVLRSILMEDEKVKAAAYSIDHPIVGEPQLYIRAGSPKKSLKAAAET.................................................................................................................................................................................................... 70
7 -5.230[L] COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)  ali follow..  6  1MRVKAYLEVPKEISFYRRSFLSLIKKALEKEDENYAKDLFQKKNFKPFTFCVFFENIRINGEILENNGKAIMTVSGSPDFFHRFYNGLKKLREYNGRYTNGNIKVK-KVLMCEEEQITKPRQTFRTLSPIVVINRDKKPVLPSKLGNRNDDFILYDDGAFTQELRY......................................................................................................................... 167
8 -4.970[S] COG1710 Uncharacterized protein conserved in archaea  ali follow..  14  43VRILDNAPNVKVIGCPPSLYPKVSKKVLRALEQMGIKVIPVEKGRGRPRKYSYKTLMMIEELLKKGKTPREISLGIPIRTLYYLLKKREVSE................................................................................................................................................................................................... 136
9 -4.870[K] COG4578 Glucitol operon activator  ali follow..  14  15AQLALGGWQISRFNRAFDTLCQQGRVGV-RFKPRVVVAIALDDQQRIADTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPHDPLSQNALSLALKLKR........................................................................................................................................................................................... 118
10 -4.840[S] COG4907 Predicted membrane protein  ali follow..  6  1MK------KNILRIFLFLIISIISFSASFSISDLDVEAK-LQKDGSMLVSEAVTYD--IDEIN-GYGGITSLQVFEDEGHYENNVISYREVDPVNYEVTENDGVYRIKLYSKNYNNVRTFK-FVYTLPEAIKVYNDVAQLNQQGISTVKVTIELPVSNDYDNSKVLVFGHGPLTGEVDKIENTVVYRLDGDFLEAHILMEPVIFSEFNVSNVIHKNMKQELLDMEARLAD......................................................... 240
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.