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Query: [K] KOG3815 Transcription factor Doublesex, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSSLast
1 -129.000[K] KOG3815 Transcription factor Doublesex  ali  100  1MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS 472
2 -16.200[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  10  14.......................RRKRACFDCK-----------RYYC--ANCRCKRCSVFASRTDLLKLKPKLQSKHISEKEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVS............................................................................................................................................................................................................................................................................................................... 164
3 -14.100[O] KOG0802 E3 ubiquitin ligase  ali follow..  342LHAA----------PDATSEELRAYDDECAICREP-MAKAKRNH---CSWLD-SCPTC-----RKPLFVGRTENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFPAEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTALDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAET------------------------VREVMPHVPDEIIFQVNFK....................................................................................................................................................................................................... 588
4 -13.700[K] KOG4218 Nuclear hormone receptor betaFTZ-F1  ali follow..  20  1MSSNSDTGDLQESLKHGLTPIVSQFKMVCPVCGDHGLLTC-KGFKR-CI-QNCRCPYCRF----QKCLS--VGMKLEAVRADRM.................................................................................................................................................................................................................................................................................................................................................................................................... 115
5 -13.300[O] KOG3579 Predicted E3 ubiquitin ligase  ali follow..  26  451.GAGNTGGLEPVHPASLPDSSLATSAPCCTLCHEHFVQCPVPSHK-FC----CSCEKCPLV-EIATILAGDVKVKKERDS........................................................................................................................................................................................................................................................................................................................................................................................................ 560
6 -13.300[O] KOG1645 RING-finger-containing E3 ubiquitin ligase  ali follow..  11  71IDVLDSPVRVSQNESEGIENQNRRMS-RDCLVKFGPAVANTKGI-IVFDTSTSGFSSDEVEGSLRDVRASRVAAVDDEAHKRILFLEAKL.............................................................................................................................................................................................................................................................................................................................................................................................. 184
7 -13.000[D] KOG3056 Protein required for S-phase initiation or completion  ali follow..  27  473........................KAVICQVCKKH--LKVVDAEKRFC--KDCSCKNCAMIREKKILTGRETLSVR--GDEET..................................................................................................................................................................................................................................................................................................................................................................................................... 562
8 -12.900[T] KOG3575 FOG: Hormone receptors  ali follow..  14  1MSPLKMHVNMLQSDHALIMSSFPEPSPSCKVCDRYGASAC-LGCTVFCM-QNCACRYCRF----QKCF--AVGMHSSAIQRRDL.................................................................................................................................................................................................................................................................................................................................................................................................... 111
9 -12.700[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  207..........................PLCEYCNKR---DELFRHLRFCHF--CLCEKC---ATEQGAFRNEIEYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLARTKENFPALGGGNGGGVTGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVSNRSAAVPKKAFPALPGKGNKKNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASPSTFQKLQMVQKEEDEAKARQEALKKSAPKLTAAEFPSLGPSASASSSRTTAPKPSSGSPSLNWSKPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQEQQANKKDKKQKDKKSNQENQPKTAKPKERNNNNEQKTNGAPSTPIRAPPGLKPGGPLKP 686
10 -12.700[R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  214..................NSEGFKGHPMCAFCSGKRFYS-LYIHMRKCH---CVCTVQTCLDNKFVVFKDELELQAHILQEHGNILKGKPKFFQSELSTFISAPSRVIRERDDYDLPSISSLPGSSSGSRTDVRSASSPEESRLRLAERAKYYLENSKEDFNKFSSYNEDYSKGRLSAEKLLESYKLLFTKPNADVYLLIHNLAETFPKNSSKYNNLNAIYEQREQTLARQTS-------------------------LPS---------LSSDSSLSMSIGRGHWGGTNDGGSAGAALGVRNIKNLPTLKSPSASYDPFATTVKKNTLRPVQNIKRTTPQSVSYRTSTNTVAFSPTYLESKKGSSSTSLNNSKDKLKSLNLPQLPPPKPKVQIPGLNRPQIADPKQWGKKSSTQDT-------------------------NVHDNLRELNTTSGGNKKKGKQKQLL.... 634
11 -12.500[O] KOG3800 Predicted E3 ubiquitin ligase containing RING finger, subunit of transcription/repair factor TFIIH and CDK-activating kinase assembly factor  ali follow..  21  2...........................ECKKCKSNEYTNKLVGHP-LC--KNCNCHVCNRVLRKNNLIDKETFLRRKLRKIYNLKQD................................................................................................................................................................................................................................................................................................................................................................................................. 84
12 -12.500[O] COG5243 HRD ubiquitin ligase complex, ER membrane component  ali follow..  327LDDT-------VTVTVEQLQNSANDDNICIICMDE--KKPKRGH---CNWRSQTCPIC-----RLPVFDEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAMRTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIENHEVNSLHGDGGE................................................................................................................................................................................................................................................................................. 535
13 -11.800[R] KOG3612 PHD Zn-finger protein  ali follow..  11  805LEQERDRLIAEVKKQLELEKQQAVDETKCANCKKEAI---------YCCWNTSYCDPCQ--PEHMK-SCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGS.......................................................................................................................................................................................................................................................................................................................................................... 928
14 -11.700[R] COG5048 FOG: Zn-finger  ali follow..  22  547.......................DKTFECLGCRRYNIRSHIQTHRPYCDHPGCACP-C-------KKFNREDALVVHRSRM....................................................................................................................................................................................................................................................................................................................................................................................................... 630
15 -11.700[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  11  104.KNQVKNNGQTMDANCNNNVSNDANVPVCKNCLT--STTPL--------WRAMLCNACGLFLKRPISLKTDVIKSRNRKSNTNHA................................................................................................................................................................................................................................................................................................................................................................................................... 187
16 -11.700[K] KOG4215 Hepatocyte nuclear factor 4 and similar steroid hormone receptors  ali follow..  18  26...TMGNDTSPSEGTNLNAPNSLGVSALCAICKHYGASSCCKGFRR-CR-RQCQCRYCRL----KKCF--RAGMKKEAVQNER..................................................................................................................................................................................................................................................................................................................................................................................................... 125
17 -11.600[O] COG5574 RING-finger-containing E3 ubiquitin ligase  ali follow..  16  359...........................ECAICSN--AYKPVRSHV-FC--LHCFCPLC-----RAKEVMREIKEKFEENENDTFTPS................................................................................................................................................................................................................................................................................................................................................................................................. 442
18 -11.500[O] KOG4265 Predicted E3 ubiquitin ligase  ali follow..  10  250LQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLI-RHLCLC--TSCNCPIC-----RLFPGPP-ADPGGAEEARSPVPRVLQ............................................................................................................................................................................................................................................................................................................................................................................................... 341
19 -11.500[O] KOG0320 Predicted E3 ubiquitin ligase  ali follow..  26  265...........................KCPICMDREPVSTKCGH--FC--RECKCPIC-----NKKLTARQF................................................................................................................................................................................................................................................................................................................................................................................................................ 314
20 -11.400[O] KOG1813 Predicted E3 ubiquitin ligase  ali follow..  25  276...........................ACFICREDPVVT---KH--FC--EHCKCFVC--IFNAAHEIKKRMAEERSKAEQGLRRLW................................................................................................................................................................................................................................................................................................................................................................................................. 347
21 -11.300[V] COG3183 Predicted restriction endonuclease  ali follow..  16  165.LTSSIVESTPEGKKILCYTTRYERNAQCQGCKTYGEIG-IEVHH-----TDLICANCHRMIHRRKLKELQELLLANKS......................................................................................................................................................................................................................................................................................................................................................................................................... 279
22 -11.200[R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers  ali follow..  17  243..................KNEKKEDIPVCLICKKSPIAT---GHH-FC--EQCTCIQC--LFSVDKNFDRLLKNRKSKNDEAVKQ................................................................................................................................................................................................................................................................................................................................................................................................... 322
23 -11.100[U] KOG3799 Rab3 effector RIM1 and related proteins, contain Rab3a binding domain  ali follow..  19  56LSELDKQITERKETSKKLVGTQDDAI--CQICQK-GI-----GH-FYCQLRSCACG-CSLCQKRQQILAKT................................................................................................................................................................................................................................................................................................................................................................................................................. 136
24 -11.100[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  26  2MQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHKFILKVLDHSS-CQ-RACKCTAC--IPPTQVVRKAQIICNRQLATGDE..................................................................................................................................................................................................................................................................................................................................................................................................... 129
25 -11.000[O] KOG0823 Predicted E3 ubiquitin ligase  ali follow..  19  89.NGENKTYLIAKALNMEKTSSVPGGFFDCNICAEDPILT---GH--FC-W-GCECPVC-----DGEVTDAEVI--NGDDCDGTKP................................................................................................................................................................................................................................................................................................................................................................................................... 180
26 -11.000[T] KOG4846 Nuclear receptor  ali follow..  17  123VTSSLSPPDSLSNGHTTQRHHIGKAISFCKVCGDHGVTSC-KGFRR-CL-QVCRCQYCRF----KKCLD--SGMSKDSVRQMKF.................................................................................................................................................................................................................................................................................................................................................................................................... 226
27 -10.900[T] KOG4825 Component of synaptic membrane glycine-, glutamate- and thienylcyclohexylpiperidine-binding glycoprotein (43kDa)  ali follow..  22  775.......................KHCLRCDHCKQ---ISSLTEH---CGFGKCRCNRCPLCHEKAHLMGPA---RKTHILQKAPALQPGKSSAVAASGPLGSKAGSKIPTPKGGLSKSSSRTYAK........................................................................................................................................................................................................................................................................................................................................................... 924
28 -10.900[K] KOG4216 Steroid hormone nuclear receptor  ali follow..  23  71.AKNFINLREFFSFLLPALRKAQIEIIPCKICGDHGVITC-KGFRR-CP-KNCRCQHCRL----QKCLA--VGMSRDAVKFGR..................................................................................................................................................................................................................................................................................................................................................................................................... 172
29 -10.900[O] KOG4628 Predicted E3 ubiquitin ligase  ali follow..  10  207RHRLPKSMLKKLPVLRYTKNNANNKYDTCVICRSHPY------HTH-C-W---VCPIC-----KRKVFTKG-----ARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHERINPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAPPYLERVESGTSAMGLPVTGTIAV----------ASPASNNILNPNLSGSFKDEDDMPPHRSIYEPIAISTPAADSATVDDSAFLQTPTQGGIGVAALPHSASDR........................................................................................................................................... 532
30 -10.800[S] KOG4623 Uncharacterized conserved protein  ali follow..  96SKGSSSICANSYYSDVLTAQPPAPKNGLCDQCEAQRLKQELKVYRERLQFR--LCSSCERHVNEKKKMVLSSKFLNYIIKGASLLKQPHFNRLAAAQKQF-----SGYAMGIEFLDPYISGISFILVGSFVTLVLLATNRTNLLSQVNRDESACESFHRLCADECDDETLSMLSQQLSGYSDISNSNLSMRTASVCHSPAPTISQRTIQAPASLLSLDSLHLSKQRMEQQAWSSNYGDASTVVAPRVQPAM-----------------------------------MFQQKPMRPLESQWYRHGQSNLAQGNTFTRSTQNLLMPSRLPSINRNVGGADVSAWVAANQSVNQDLCTANLMRHYEEKQQNQLSRTSSQSSGFESQPRP------EAQCGTGAATVRDYGWSEARESQRNFAVFPP-MPSPTPTITPSEYQYSRTALPQQQPTMQPGDLLRK--WIEINSKSSQ. 677
31 -10.600[O] KOG0824 Predicted E3 ubiquitin ligase  ali follow..  17  1MNASTSSPSQQLQQAINSTID------ECAVCYS--MILPTTGHK-FC--FICDCPIC-----RGPIDSQIFKKPLQAVDLKMD.................................................................................................................................................................................................................................................................................................................................................................................................... 84
32 -10.600[R] KOG1819 FYVE finger-containing proteins  ali follow..  16  567.......................EDCEQCTACRRH--------H---C--RNC-CHKCSI-YDRKPVVSSPQSLSLLTRQDQFSCNLLHQSHHIHHLFNRSL.................................................................................................................................................................................................................................................................................................................................................................................. 652
33 -10.500[T] COG5432 RING-finger-containing E3 ubiquitin ligase  ali follow..  17  1MD-HQITTASDFTTTSIPSLYQLDTLLRCHICKD--LKVPV-GHT-FCS---CNCPLC-------LFEFRESLLRSEFLVSE...................................................................................................................................................................................................................................................................................................................................................................................................... 82
34 -10.500[L] KOG0287 Postreplication repair protein RAD18  ali follow..  17  1MD-HQITTASDFTTTSIPSLYQLDTLLRCHICKD--LKVPV-GHT-FCS---CNCPLC-------LFEFRESLLRSEFLVSE...................................................................................................................................................................................................................................................................................................................................................................................................... 82
35 -10.300[R] KOG3002 Zn finger protein  ali follow..  21  1MAPGGSALKEALESNSTGVDYEVKMAKECPVCTN--IHQCPNGH--LC--SSCTCPTCRYELGNIRCLALEKVAES............................................................................................................................................................................................................................................................................................................................................................................................................ 110
36 -10.300[DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3  ali follow..  16  1MDDEGA----------------RKVDEKCPLCQNPNMKLLINYHK-MC--ESCVTPGCNKILRKAKQIEREVDVRKRISRIFNK.................................................................................................................................................................................................................................................................................................................................................................................................... 94
37 -10.200[S] KOG2660 Locus-specific chromosome binding proteins  ali follow..  20  4................KVKKETMRACLSCSICDNI-----LRDATTIS--EKCTCPVCKLRPDHQDLRAKIFALKRRKVKAPGI.................................................................................................................................................................................................................................................................................................................................................................................................... 87
38 -10.100[R] KOG4299 PHD Zn-finger protein  ali follow..  239.EGRAEDISSNELLPTPEEYPYRYNNDYCSACHGPGNFLCCETH---CAW---YCNECKHHSLYNELDEQEELESNVKEEGTMVD................................................................................................................................................................................................................................................................................................................................................................................................... 336
39 -10.100[OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger  ali follow..  31  58.......................EAAPKCNNCSQRGHLKATDDHAIQCS-SQCQCTLC.............................................................................................................................................................................................................................................................................................................................................................................................................................. 126
40 -10.000[O] KOG1571 Predicted E3 ubiquitin ligase  ali follow..  19  263.KIRERLDTERRERRARSRPHTLSQDQLCVVCSTNPKEIIL-GHVCLC--EDCTCPVC-----RGSIVSK-AAA.............................................................................................................................................................................................................................................................................................................................................................................................................. 335
41 -9.820[U] KOG2114 Vacuolar assembly/sorting protein PEP5/VPS11  ali follow..  19  813VEKYQETTKNMRKEIEDLRTNAR-QLSKCTACTMHSF------HQR-C--NEKECPECA--PEYRSVMEMKRSLEQNSKDQDL..................................................................................................................................................................................................................................................................................................................................................................................................... 900
42 -9.810[R] KOG2893 Zn finger protein  ali follow..  20  2................GRKKKKQLK-PWCWYCRDFDDEKILIQHQKAKHFK---CHIC-----HKKLYTG-LAIHCMQVHKET..................................................................................................................................................................................................................................................................................................................................................................................................... 61
43 -9.790[O] KOG0317 Predicted E3 ubiquitin ligase, integral peroxisomal membrane protein  ali follow..  20  270LSDKNQLPFIPEASRKCILCLMNMSDPSCAPC----------GH--FC-W-SCECPLC-----RQHCQPQEILLRQ............................................................................................................................................................................................................................................................................................................................................................................................................ 337
44 -9.690[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  23  5...........................QCDDC---G--ENLKRHMSMCT--SCICGQC--ITEAEKY-GPMVRSNGESSKQKH..................................................................................................................................................................................................................................................................................................................................................................................................... 72
45 -9.630[R] COG5084 Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins  ali follow..  20  259.......................RRIPACGKCNNHGFCE--LGHILQC-YAMCNNPQCSLYHGAVSADVPEQTEAPISKTAGSIN................................................................................................................................................................................................................................................................................................................................................................................................... 355
46 -9.630[S] KOG4020 Protein DRE2, required for cell viability  ali follow..  17  274LDPEDLKKPDPASLRAASCGEGKKRKA-CKNC---GLAEELEKEKS-C---NCRCASCPYL------MPAKVLLSDSNLHDA...................................................................................................................................................................................................................................................................................................................................................................................................... 367
47 -9.610[S] KOG4317 Predicted Zn-finger protein  ali follow..  19  2MP---EKTIISSESSNSSPLNPSSTRIICHVCN--------KQFSQYCNFRYCSCYKCTESFMRDNVND---ELKQVRSDDQTKRKMLEIL............................................................................................................................................................................................................................................................................................................................................................................................. 89
48 -9.580[R] KOG1313 DHHC-type Zn-finger proteins  ali follow..  22  96FKCAGKPTNILYGTHPGVGNGALNNYTFCNYCRTH--------H---CR----TCGMCVLDMDHH--IGNCVGAGNHK.......................................................................................................................................................................................................................................................................................................................................................................................................... 165
49 -9.480[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  10  600............................CEMLDAKG--TEIVRKNLYRNFI------CSLLIAAETVYKTVQKLQGLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSS-----------------------------------------------KDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRR------------------------EEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPPQ................. 955
50 -9.450[R] KOG4582 Uncharacterized conserved protein, contains ZZ-type Zn-finger  ali follow..  20  126...........................ECDGCG----LAPLIGFRYKCV--QCLCQKCELAHKHPEHLMLRMPTNNGPGMVDA..................................................................................................................................................................................................................................................................................................................................................................................................... 179
51 -9.370[O] KOG1100 Predicted E3 ubiquitin ligase  ali follow..  15  260.GDSEEERWKLAGEAQDTKKMCRVGMSMCRSCGKGEASVLL-RHMCLC--SVCTCPICKSPKTASHVNLSS................................................................................................................................................................................................................................................................................................................................................................................................................. 335
52 -9.340[S] KOG4367 Predicted Zn-finger protein  ali follow..  24  172..................EKAPKEATVMCEQCAKHRLVPPAQGHELYC--VQCKCYQCLEEGKHSEVKALGAMWKLHKSQ........................................................................................................................................................................................................................................................................................................................................................................................................ 276
53 -9.330[R] COG5063 CCCH-type Zn-finger protein  ali follow..  19  146FSSEKESSAQPKVKSQVQETPKQLKTELCSKCQ-HG-LGELKVKKSCKNFRTCVCRRCCFKHGDDNDIAVYVKAGTYCNVSST..................................................................................................................................................................................................................................................................................................................................................................................................... 253
54 -9.290[R] KOG4377 Zn-finger protein  ali follow..  18  405...........................HCRKC-DYVCTNKVVAHRRLCDSPGCSCVTC--VLSRAQLAA-----KHRTGFPKQEA................................................................................................................................................................................................................................................................................................................................................................................................... 489
55 -9.290[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  20  2.........................MVHCAGCERH--IKCVQ---CECK-RECKCAGC--ISPSDLVRKARMVCNKQLSTGEE..................................................................................................................................................................................................................................................................................................................................................................................................... 104
56 -9.290[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  17  819LEELGSESVEAAIVRLQEEVKNCKNILKCGVCFDRPKEVVIVYH--FC--QQCKCPGCGTAFGQNDVR--LVKM.............................................................................................................................................................................................................................................................................................................................................................................................................. 899
57 -9.260[O] KOG1734 Predicted RING-containing E3 ubiquitin ligase  ali follow..  16  271...TARMASRIGYYTPEGLPKKHLEDGVCAVCGGHVF------HE-FCGWKLQTCPYC-----KERVDLQRMFKNPWEKPH....................................................................................................................................................................................................................................................................................................................................................................................................... 375
58 -9.170[S] KOG4791 Uncharacterized conserved protein  ali follow..  22  15...........................TCTKCR-H---EAALGNETVCTWQEC-CLNCVFHHNRGRLPPSKSVLPTVPESPEEE.................................................................................................................................................................................................................................................................................................................................................................................................... 112
59 -9.140[DR] KOG1101 Apoptosis inhibitor IAP1 and related BIR domain proteins  ali follow..  21  544.NMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVF-GHLVVC--QECKCPIC-----RGIIKGTRTFL.............................................................................................................................................................................................................................................................................................................................................................................................................. 617
60 -9.050[DR] KOG4739 Uncharacterized protein involved in synaptonemal complex formation  ali follow..  22  6............................CNHCGI--LTAC--GH--FC--QNCQCYLCQLASDLVNELKQVVAFQAKQREI....................................................................................................................................................................................................................................................................................................................................................................................................... 91
61 -9.050[K] KOG4217 Nuclear receptors of the nerve growth factor-induced protein B type  ali follow..  23  265.PTASSLLGESPSLPSPPSRSSSSGEGTCAVCGDHGVRTCCKGFKR-CL-KNCRCQYCRF----QKCLS--VGMVKEVVRTDSLKGRRGRLPSKPKSPLQQEPSQPSPPSPP........................................................................................................................................................................................................................................................................................................................................................................ 395
62 -9.020[S] COG5255 Uncharacterized protein conserved in bacteria  ali follow..  26  1MSRPSSPAYRPNRSASASTAAP----PNATRCLPGGT-----GTTRGCARRSRIFASC-----RQR---------RNTGDSSSHHRNQG............................................................................................................................................................................................................................................................................................................................................................................................... 71

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]