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KOG3815
Query: [K] KOG3815 Transcription factor Doublesex, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSSLast
1 -136.000[K] KOG3815 Transcription factor Doublesex  ali  100  1MNGYGSPYLYMGGPVSQPPRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRPAAELAAAAALRWTAEPQPGALQAQLAKPDLTEERLGDGKSADNTEVFSDKDTDQRSSPDVAKSKGCFTPESPEIVSVEEGGYAVQKNGGNPESRPDSPKCHAEQNHLLIEGPSGTVSLPFSLKANRPPLEVLKKIFPNQKPTVLELILKGCGGDLVSAVEVLLSSRSSVTGAERTSAEPESLALPSNGHIFEHTLSSYPISSSKWSVGSAFRVPDTLRFSADSSNVVPSPLAGPLQPPFPQPPRYPLMLRNTLARSQSSPFLPNDVTLWNTMTLQQQYQLRSQYVSPFPSNSTSVFRSSPVLPARATEDPRISIPDDGCPFVSKQSIYTEDDYDERSDSSDSRTLNTSS 472
2 -18.600[O] KOG0802 E3 ubiquitin ligase  ali follow..  10  348...............DATSEELRAYDDECAICRNH--------HLG-CSWLD-SCPTC-----RKPLFVGRTENEVNPRTVEVSSDEQLARQLERQNNPVHALATGLFPAEVPDSVENDTSRNLGLDPSWLQTWSSQGSDVAGPSTTSRTVGLGRVQMMMRHLASVGESYAQTALDDAAWSLWPMNPSQASTSSTTVPPGNGGRTGGLHLRTVSNTTNESLTNILAMAETVREVMPHVPDEIIFQVNFKCILDYL......................................................................................................................................................................................................................... 594
3 -18.100[O] KOG4275 Predicted E3 ubiquitin ligase  ali follow..  10  3............................CESC---GVEFTVFRRKRAC---DCKCKRCSVFASRTDLLKLKPKLQSKHEKEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNGGSQSS-----SSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQS........................................................................................................................................................ 312
4 -16.900[R] KOG1819 FYVE finger-containing proteins  ali follow..  17  567.......................EDCEQCTACRRH--------H---C--RNC-CHKCSYDRKPVVS-QSNLSLLTRQDQFSCNLLHQSHHIHHLFNRSLVPHT................................................................................................................................................................................................................................................................................................................................................................................ 656
5 -16.400[O] COG5243 HRD ubiquitin ligase complex, ER membrane component  ali follow..  9  332...........VTVTVEQLQNSANDDNICIICMGH--------HLS-CNWRSQTCPIC-----RLPVFDEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANEVDLLPTRTTSPDIRIVPTQNIDTLAMRTRSTSTPSPTWYTFPLHKTGDNSVGSSRSAYEFLITNSDEKENGIPVKLTIENHEVNSLHGDGGEQIAKKIVIPDKF..................................................................................................................................................................................................................................................................... 547
6 -16.000[K] KOG4218 Nuclear hormone receptor betaFTZ-F1  ali follow..  15  1MSSNSDTGDLQESLKHGLTPIVSQFKMVCPVCGDHGLLT--KGFKRTCI-QNCRCPYCRF-MKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKGLPLNHAALPPTD....................................................................................................................................................................................................................................................................................................................................... 188
7 -15.100[L] KOG0287 Postreplication repair protein RAD18  ali follow..  16  1MDHQITTASD--TTTSIPSLYQLDTLLRCHICKD--LKVPV-GHT-FC--SLCNCPLCLFEFRESEIIQSYTSLRSSLLDALRIP................................................................................................................................................................................................................................................................................................................................................................................................... 101
8 -15.100[T] COG5432 RING-finger-containing E3 ubiquitin ligase  ali follow..  16  1MDHQITTASD--TTTSIPSLYQLDTLLRCHICKD--LKVPV-GHT-FC--SLCNCPLCLFEFRESEIIQSYTSLRSSLLDALRIP................................................................................................................................................................................................................................................................................................................................................................................................... 101
9 -14.700[O] KOG0823 Predicted E3 ubiquitin ligase  ali follow..  19  89.NGENKTYLIAKALNMEKTSSVPGGFFDCNIC-EDPILTC--GH--FC--WGCECPVCDGEVTDAEVIGDDCDGTKPKLEDCGISLPPR............................................................................................................................................................................................................................................................................................................................................................................................... 192
10 -14.000[D] KOG2186 Cell growth-regulating nucleolar protein  ali follow..  21  5...........................QCDDC---G--ENLKRHMSMCT--SCDCNQC--ITEAEKYGPMVRSNGESSKQKHDF.................................................................................................................................................................................................................................................................................................................................................................................................... 74
11 -14.000[O] KOG4265 Predicted E3 ubiquitin ligase  ali follow..  10  250LQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLI-RHLCLC--TSCNCPIC-----RLFPGPPDPGGAEEARSPVPRVLQPRPGPEPGA........................................................................................................................................................................................................................................................................................................................................................................................ 350
12 -13.900[K] KOG4216 Steroid hormone nuclear receptor  ali follow..  22  71.AKNFINLREFFSFLLPALRKAQIEIIPCKICGDHGVIT--KGFRRSCP-KNCRCQHCRL----QKCLA--VGMSRDAVKFGRM.................................................................................................................................................................................................................................................................................................................................................................................................... 173
13 -13.400[R] COG5236 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  9  214..................NSEGFKGHPMCAFCSGKRFYS-LYIHMRKCH---CVCTTCL--DNKFVVFKDELELQAHILQEHGNILKGKPKFFQSELSTFISAPSRVIRERDDYDLPSISSLPGSSSGSRTDVRSASSPEESRLRLAERAKYYLE----------------------------------------------------NSKEDFNKFSSYNEDYSKGRLSAEKLLESYKLLFTKPNADVYLLIHNLAETFPKNSSK--YNNLNAIYEQREQTLARQTSLPSLSSDSSLSMSIGRGHWGGTNDGGSAGAALGVRNIKNLPTLKSPSASYDPFATTVKKNTLRPVQNIKRTTP-------QSVSYRTSTNTVAFSPTYLESKKGSSSTSLNNSKDKLKSLNLPQLPPPKPKVQIPGLNRPQIADPKQWGKKSST-----QDTNVHDNLRELNTTSGGNK...... 625
14 -13.400[O] KOG1100 Predicted E3 ubiquitin ligase  ali follow..  19  274...............QDTKKMCRVGMSMCRSCGKGEASVLL-RHMCLC--SVCTCPIC-----KSPKTASHVNLSS............................................................................................................................................................................................................................................................................................................................................................................................................ 335
15 -13.100[O] COG5574 RING-finger-containing E3 ubiquitin ligase  ali follow..  16  359...........................ECAICSN--AYKPVRSHV-FC--LHCFCPLCALMNFMKTYFPREIKEKFEENENDTFTPS................................................................................................................................................................................................................................................................................................................................................................................................. 442
16 -12.900[O] KOG3579 Predicted E3 ubiquitin ligase  ali follow..  21  452.AGNTGGLEPVHPASLPDSSLATSAPLCCTLCHEHFVQCPVPSHK-FC----CSCEKCPLV-EIATILAGDVKVKKERDS........................................................................................................................................................................................................................................................................................................................................................................................................ 560
17 -12.900[O] KOG1571 Predicted E3 ubiquitin ligase  ali follow..  21  271.........ERRERRARSRPHTLSQDQLCVVCSTNPKEIIL-GHVCLC--EDCTCPVC-----RGSIVSK.................................................................................................................................................................................................................................................................................................................................................................................................................. 332
18 -12.900[O] KOG1813 Predicted E3 ubiquitin ligase  ali follow..  19  276...........................ACFICREDPVVTK--KH--FC--EHCKCFVC-----NQPTMGIKKRMAEERSKAEQG.................................................................................................................................................................................................................................................................................................................................................................................................... 342
19 -12.800[R] COG5152 Uncharacterized conserved protein, contains RING and CCCH-type Zn-fingers  ali follow..  19  253...........................VCLICKK--YRSPI-GHH-FC--EQCTCIQCGADTKGDRLLKNRKSKNDEAVKQKV..................................................................................................................................................................................................................................................................................................................................................................................................... 324
20 -12.800[O] KOG0320 Predicted E3 ubiquitin ligase  ali follow..  26  265...........................KCPICKREPVSTK--GH--FC--RECKCPIC-----NKKLTARQF................................................................................................................................................................................................................................................................................................................................................................................................................ 314
21 -12.600[O] KOG0824 Predicted E3 ubiquitin ligase  ali follow..  18  1MNASTSSPSQQLQQAINSTID------ECAVCYSLPTTIPSCGHK-FC--FICDCPIC-----RGPIDSQIFKKPLQAVD........................................................................................................................................................................................................................................................................................................................................................................................................ 80
22 -12.300[O] KOG3800 Predicted E3 ubiquitin ligase containing RING finger, subunit of transcription/repair factor TFIIH and CDK-activating kinase assembly factor  ali follow..  24  2...........................ECKKCKSNEYTNKLVGHP-LC--KNCNCHVCNRVLRKNNLIDKETFLRRKLRK........................................................................................................................................................................................................................................................................................................................................................................................................ 77
23 -12.200[R] KOG4299 PHD Zn-finger protein  ali follow..  14  266............................CSACHGPGNFLCCET----CPFHTCICNECKHHSLYNELDEQEELESNVKEEGT...................................................................................................................................................................................................................................................................................................................................................................................................... 333
24 -12.100[R] KOG3002 Zn finger protein  ali follow..  21  1MAPGGSALKEALESNSTGVDYEVKMAKECPVCTN--IHQCPNGHT-LC--SSCTCPTCRYELGNIRCLALEKVAES............................................................................................................................................................................................................................................................................................................................................................................................................ 110
25 -11.700[DKL] COG5220 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3  ali follow..  16  1MDDE----------------GARKVDEKCPLCQADRYLNPMKYHK-MC--ESCPTPGCNKILRKAKFIEREVDVRKRISRIFNK.................................................................................................................................................................................................................................................................................................................................................................................................... 94
26 -11.700[OU] COG5082 Arginine methyltransferase-interacting protein, contains RING Zn-finger  ali follow..  32  53..................KDAIKEAAPKCNNCSQ-------RGHKKDCP-RHCQCSKC.............................................................................................................................................................................................................................................................................................................................................................................................................................. 104
27 -11.600[O] KOG2231 Predicted E3 ubiquitin ligase  ali follow..  10  207..........................PLCEYCFRH--YADLAEHFRACEEGKCATEQFV------GAFRNEIEYKAHVANVHGKSLNKQQAKQTRTLQVEITLGPRGRSGQTEQGITSVRTRNDEHNDYQNDLPSITQRHVSIDAGNEEQFPTLRGASTAPSVSLVRPPPPSMRNLSGTSGLARTKENFPALGGGNGGGVTGPTSSSIAARAAQSQHPVAAVFKKPTSAAGSGSRSGPPGNGMLLHVSNRSAAVPKK--AATPQVDFPALPGKGNKKNLRNLEEDMLPSGSPVPMANISAKHRSLADDYVSVASPSTFQKLQMVQKEEDEAKARQEALKKSAPKLTAAEFPSLGPSASASSSRTTAPKPSSGSPSLNWSKPANEKKQRELENRKAKVAPAPVLPSPTSKPAPKASNNNVQEQQANKKDKKQKDKKSNQENQPKTAKPKERNNNNEQKTNGPSTPIRAPPGLK 679
28 -11.600[R] KOG1312 DHHC-type Zn-finger proteins  ali follow..  16  143.....................KPARSKHCSICNRH--------H---CIWNNC-------IGKGNYLISNIFSM.............................................................................................................................................................................................................................................................................................................................................................................................................. 190
29 -11.500[O] KOG1734 Predicted RING-containing E3 ubiquitin ligase  ali follow..  12  286LPKKHLEDGVCAVCGGRLDDSEHVHDADAVSC-GHVF------HEF-CGWKLQTCPYC-----KERVDLQRMFKNPWEKPHLF..................................................................................................................................................................................................................................................................................................................................................................................................... 377
30 -11.500[S] KOG4791 Uncharacterized conserved protein  ali follow..  25  2......................PNQGEDCSTCT--------KGDS--CPFRHCRCFRC.............................................................................................................................................................................................................................................................................................................................................................................................................................. 50
31 -11.500[R] KOG4582 Uncharacterized conserved protein, contains ZZ-type Zn-finger  ali follow..  18  126...........................ECDGCGLA----PLIGFRYKC--VQCSCQKC--ELAHKHPEHLMLRMPTNNGP........................................................................................................................................................................................................................................................................................................................................................................................................ 174
32 -11.400[DR] KOG4739 Uncharacterized protein involved in synaptonemal complex formation  ali follow..  17  5...........................QCNHCNQTKLYLTACGH--FC--QNCQCYLC-----KKPLKVDEIN............................................................................................................................................................................................................................................................................................................................................................................................................... 53
33 -11.400[K] COG5641 GATA Zn-finger-containing transcription factor  ali follow..  14  118...............CNNNVSNDANVPVCKNCLT---TTPL--------WRAMLCNACGLFLKRPISLKTDVIKSRNRKSNTNHA................................................................................................................................................................................................................................................................................................................................................................................................... 187
34 -11.300[R] KOG1313 DHHC-type Zn-finger proteins  ali follow..  22  96FKCAGKPTNILYGTHPGVGNGALNNYTFCNYCRTH--------H---CR----TCGMCVLDMDHH--IGNCVGAGNHK.......................................................................................................................................................................................................................................................................................................................................................................................................... 165
35 -11.300[O] KOG1645 RING-finger-containing E3 ubiquitin ligase  ali follow..  9  71IDVLDSPVRVSQNESEGIENQNRRMS-RDCLVKFGPAVANTKGI-IVFDTSTSGFSSDEVEGSLRDVRASRVAAVDDEAHKRILFLEAKLRSIEQKTASWSNKEVQ.............................................................................................................................................................................................................................................................................................................................................................................. 200
36 -11.200[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  26  2.........................MVHCAGCER-RFLLNVLDHIKECK-RECKCAGCA-ISPSDLVRKAR................................................................................................................................................................................................................................................................................................................................................................................................................. 81
37 -11.000[R] KOG1842 FYVE finger-containing protein  ali follow..  15  178.....................DDAEAVCCPLCRRH--------H---C--RLC-CHSCS-LTSSSNP-DTHIIVEEPNTVENEQE................................................................................................................................................................................................................................................................................................................................................................................................... 249
38 -11.000[R] COG5048 FOG: Zn-finger  ali follow..  17  547.......................DKTFECLGCKTFKRRYNIRSHIQSCDHPGCACP-C-------KKFNREDALVVHRSR........................................................................................................................................................................................................................................................................................................................................................................................................ 629
39 -10.900[K] KOG4215 Hepatocyte nuclear factor 4 and similar steroid hormone receptors  ali follow..  20  26...TMGNDTSPSEGTNLNAPNSLGVSALCAICGDHGASS--KG-RRSCR-RQCQCRYCRL----KKCF--RAGMKKEAVQNER..................................................................................................................................................................................................................................................................................................................................................................................................... 125
40 -10.900[T] KOG4846 Nuclear receptor  ali follow..  15  123VTSSLSPPDSLSNGHTTQRHHIGKAISFCKVCGDHGVTS--KG-RRRCL-QVCRCQYCRF----KKCL--DSGMSKDSVRQMKFRNAMRDDKSPDSVFVPEISTLE.............................................................................................................................................................................................................................................................................................................................................................................. 248
41 -10.900[S] KOG4020 Protein DRE2, required for cell viability  ali follow..  16  276.PEDLKKPDPASLRAASCGEGKKRKA--CKNCT--GLAEELEKEKS-C---NCRCASCPYL------MPAKVLLSDSNLHDA...................................................................................................................................................................................................................................................................................................................................................................................................... 367
42 -10.800[S] KOG2660 Locus-specific chromosome binding proteins  ali follow..  10  2..............MIKVKKETMRACLSCSICDN------RDATT-IS--EKCTCPVCNILRPDHNLQDLRAKIFALKRRKVKA.................................................................................................................................................................................................................................................................................................................................................................................................... 84
43 -10.800[T] KOG3575 FOG: Hormone receptors  ali follow..  11  1MSPLKMHVNMLQSDHALIMSSFPEPSPSCKVCGDRGASAAVVKNLKYCM-QNCACRYCRF----QKCF--AVGMHSSAIQRRDLVGPRKISGDGEVIICENNT................................................................................................................................................................................................................................................................................................................................................................................. 130
44 -10.700[O] KOG4628 Predicted E3 ubiquitin ligase  ali follow..  8  208.HRLPKSMLKKLPVLRYTKNNANNKYDTCVICRSHPY------HTH-CPWNRRVCPICKVFTKGEARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHERINPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAPPYLERVESGTSAMGLPVTGTIAVASPASNNILNPNLSGSFKDEDDMPPHRSIYEPIAISTPAADSATVDDSAFLQTPTQGGIGVAALPHSASDRQF.............................................................................................................................................................. 534
45 -10.700[O] KOG0317 Predicted E3 ubiquitin ligase, integral peroxisomal membrane protein  ali follow..  15  260..PKESQLTHINLSDKNQLPFIPEASRKCILCLMDPSCAP--GH--FC---SCECPLCRQHCQPQEILVLR................................................................................................................................................................................................................................................................................................................................................................................................................. 336
46 -10.500[R] KOG4323 Polycomb-like PHD Zn-finger protein  ali follow..  16  197...............QRGHSPLSNRIVFCDGC-NSPY------HQ-LCEW----CMKCQYRRAKQPLETQDLGLSESDKK........................................................................................................................................................................................................................................................................................................................................................................................................ 269
47 -10.500[O] KOG0800 FOG: Predicted E3 ubiquitin ligase  ali follow..  14  90..................KESFTVMDSQCSVCQKHTF------HMD-CLWSHTTCPLC-----RLALIPSRSRQSQDDPVPSLVSPDEEVSSQPESEPVNHRVVSTQPESEPVNHSGVSSQPESQPVVNHRGVSSQPESQP........................................................................................................................................................................................................................................................................................................................................... 219
48 -10.500[O] KOG0826 Predicted E3 ubiquitin ligase involved in peroxisome organization  ali follow..  14  216GGTLINPEAMPRKQLPKEVQQSLPQRGECPVCLLTPTACSVSGY--FC---KCTCPVTHYPISLDDLVRI.................................................................................................................................................................................................................................................................................................................................................................................................................. 294
49 -10.400[R] KOG1315 Predicted DHHC-type Zn-finger protein  ali follow..  17  104.EVQKQMLVDMAKKLPVYTRTGSGAVRFCDRCRCH--------H---CS----VCAMCVLKMDHH--VNNCIGFSNYK.......................................................................................................................................................................................................................................................................................................................................................................................................... 172
50 -10.400[S] KOG2846 Predicted membrane protein  ali follow..  14  268............................CKACHAHGML--PKEEYEYTTFR---CAFCNVLNPARKKRPVAPRLSLEAPSDTANKRNDSSESESSDDDSDKEPSARRALLQKLPSGGADMDATAETEDLAMETETIETGSAAPSTAEVAASS................................................................................................................................................................................................................................................................................................................................ 387
51 -10.300[O] KOG0827 Predicted E3 ubiquitin ligase  ali follow..  19  5...........................NCVIC-GHMF------HHN-CQWRSKTCPQC-----RNKCTTRNIF............................................................................................................................................................................................................................................................................................................................................................................................................... 56
52 -10.300[K] KOG2494 C3H1-type Zn-finger protein  ali follow..  9  187...........................NCTRCRAHPTDASMDNTVTICMYIKGRCSRCKYFHPPAHLQARLKAAHHQMNHSAASAMALQPGTLQLIPKRSALEKPNGATPVFNPTVFHCQQALTNLQLPQPAFIPAGPILCMAPASNIVPMMHGATPTTVSAATTPATSVPFAAPTTGNQL................................................................................................................................................................................................................................................................................................... 352
53 -10.200[O] COG5540 RING-finger-containing ubiquitin ligase  ali follow..  14  294.EIENSTQNGELVPLMDESTRRATFGVECVIC-KHEF------HRP-CKWYRHACPTC-----NTEVPPPK................................................................................................................................................................................................................................................................................................................................................................................................................. 370
54 -10.200[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  24  24......................MQQIPQCAGCNQ-KFILKVLDHSSDCQ-RACKCTAC-----QQGIPPTQVVRKAQDFV........................................................................................................................................................................................................................................................................................................................................................................................................ 109
55 -10.000[D] KOG3056 Protein required for S-phase initiation or completion  ali follow..  23  466.................TTYKMPCKAVICQVCKKH--LKVVDAEKRFC--KDCSCKNCAMIREKKILTGRETLSVRGDEET....................................................................................................................................................................................................................................................................................................................................................................................................... 562
56 -9.980[O] KOG2164 Predicted E3 ubiquitin ligase  ali follow..  18  207.....................SDFQLAACPFCLEEKPVAAR-GH--YC--FSCSCPICWDSIRLRDVHPIRWVEDKEFQK........................................................................................................................................................................................................................................................................................................................................................................................................ 294
57 -9.970[R] KOG1314 DHHC-type Zn-finger protein  ali follow..  14  74NAMFVGPGF-VPLGWKPEISQDTMYLQYCKVCRSH--------H---CR----KCNRCVMKMDHH-INNC-CGYQNHA.......................................................................................................................................................................................................................................................................................................................................................................................................... 142
58 -9.890[S] KOG4317 Predicted Zn-finger protein  ali follow..  14  1MMPEKTIISSESSNSSPLNPSSTRII--CHVCNK-------QFSQYTCP--RCNFRYCSLPCYKSHSVQCTESFMRDNVNDELKQ................................................................................................................................................................................................................................................................................................................................................................................................... 74
59 -9.710[R] KOG0153 Predicted RNA-binding protein (RRM superfamily)  ali follow..  20  1MSKTTNTYNRQN---------EDAEFP-CQTC-DNPYVRMIKGKEKICRWC-CTCARCLLDLEGLPIQVRDAALKVADNMPQSDV................................................................................................................................................................................................................................................................................................................................................................................................... 110
60 -9.710[R] COG5273 Uncharacterized protein containing DHHC-type Zn finger  ali follow..  20  182.....................RPPRSSHCSTCNVH--------H---CIWNNC-------IGKRN-LLGAILSS.............................................................................................................................................................................................................................................................................................................................................................................................................. 229
61 -9.700[TZR] KOG1704 FOG: LIM domain  ali follow..  16  204...........................QCAQCND-DQKYMQRANKPVC--LKCSCTTC-----RLSFSSDTPHMSQGDLH........................................................................................................................................................................................................................................................................................................................................................................................................ 259
62 -9.690[O] KOG0006 E3 ubiquitin-protein ligase (Parkin protein)  ali follow..  25  377...............AASKETIKKTTKPCPRCKNGG------MHMK-CPQPQCRCWNC.............................................................................................................................................................................................................................................................................................................................................................................................................................. 421
63 -9.680[U] KOG3799 Rab3 effector RIM1 and related proteins, contain Rab3a binding domain  ali follow..  20  82............................CQICQK------ADGIGHKC--FYCQCARCRAQSKNKAIWACSLCQKRQQILAKT..................................................................................................................................................................................................................................................................................................................................................................................................... 136
64 -9.670[O] KOG2813 Predicted molecular chaperone, contains DnaJ domain  ali follow..  17  205.TGRGDVVCPTCNADGEPGFYKENQMMKCSTCYGRGLVAHKDGSDTICT-LPCKCQTCDSTGSLLTSSIAVVKWKTLSKRKVS..................................................................................................................................................................................................................................................................................................................................................................................................... 301
65 -9.590[S] KOG3740 Uncharacterized conserved protein  ali follow..  19  262.................SAATVLSREPMCAQCKTD--------------WRAIMCENCMTTNQKKALKVEHTALQQEQEIEQRLL................................................................................................................................................................................................................................................................................................................................................................................................... 334
66 -9.440[O] KOG0828 Predicted E3 ubiquitin ligase  ali follow..  21  686...............SEHGGGTAEHTVDCAICMNHVF------HTS-CNWYKLQCPVC-----RSPLPPL.................................................................................................................................................................................................................................................................................................................................................................................................................. 758
67 -9.370[R] KOG1311 DHHC-type Zn-finger proteins  ali follow..  15  78.EPTQVDDLRAPLYKNVDINGITVRMKWCVTCRSS--------HCSVC--NRCICHNC--VGKRN-LCSLSIHM.............................................................................................................................................................................................................................................................................................................................................................................................................. 159
68 -9.230[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  16  819LEELGSESVEAAIVRLQEEVKNCKNILKCGVCFDRPKEVVIVYH--FC--QQCKCPGCGTAFGQNDVRLVKM................................................................................................................................................................................................................................................................................................................................................................................................................ 899
69 -9.190[R] COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding  ali follow..  18  133..................AGPERERLKICPNCA---FLDRSRNRSR--TW--CDMAVC---GNRTKARRHY---RRSREEPKP..................................................................................................................................................................................................................................................................................................................................................................................................... 186
70 -9.150[O] KOG0712 Molecular chaperone (DnaJ superfamily)  ali follow..  18  141................SGRGGKEGSVKSCASCNGSGVKFITR--QMTCP--DCRCKECD-VISQRKILTVHVEKGMHNGQK....................................................................................................................................................................................................................................................................................................................................................................................................... 223
71 -9.130[O] KOG0801 Predicted E3 ubiquitin ligase  ali follow..  19  183...........................ECVICLECIY------HKS-CSWVNRSCPEH.............................................................................................................................................................................................................................................................................................................................................................................................................................. 224
72 -9.130[R] KOG2858 Uncharacterized conserved protein  ali follow..  15  2.........................AVLCGVCGI-------KEFKYKCP--RCLVQTCSL-SKKHKTRDNCSGQTHDPKEYISSE................................................................................................................................................................................................................................................................................................................................................................................................... 53
73 -9.130[R] KOG4602 Nanos and related proteins  ali follow..  14  221................GAPGANGGLGTLCNFCKHNG--HVYSSHQ--CP-RHYVCPVCGATGDQAHTLKQSLYRRSGRNSAGRR.................................................................................................................................................................................................................................................................................................................................................................................................... 305
74 -9.030[K] KOG2857 Predicted MYND Zn-finger protein/hormone receptor interactor  ali follow..  14  2.....................CPRATQTCEICEK-------VVSKYKCP--SCLVPYCSLGCFKIHKVCNLINNAETPCAKPSDP................................................................................................................................................................................................................................................................................................................................................................................................... 56
75 -9.020[R] KOG3138 Predicted N-acetyltransferase  ali follow..  9  1MNRPSNWDDPQGPCRYCESPVEDDNYLECQECRRH---GDLLGDVFFC--VKCVIPSDL-VIVRQRIPWLLVLLSIKQKGLGHHGIFGPNVRRRKQWTGSVSGALSHNSPEYFQSGLDVFQENG---KLAKPFQTPRSVLKEYEKKQQLRLQMRIEKRLPAADETSCSSEISVADHAQDNPPLIKAEAEKPSSTEGCARTIPYMGRLPKIQTQPSPLSQETLPGPPILQENIAPPSQKEEEPQNQPMSMVQAGLMDFLAESLESDDFTMF---------GNLPGIMPPPLIGAGKNDFFMTEPLLHAPLNNEGLFDMDTNFAIPNTADETKPISTEEPAAESSEEQKEGEVEDEKPEEDESPDYQPRIVQVTNYQAQEANESIKEEPLEEIMQDDDVTTNSKSSILEPCKPSGFVRQPRRNWPWLQEAQDPDDMAIPSENLKLINAYEEQKLYQRLDRIFALEHQCHISIPA 508
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.