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KOG1763
Query: [R] KOG1763 Uncharacterized conserved protein, contains CCCH-type Zn-finger, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPPKKQAQAGGSKKADEKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKDLQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTGKWSHLast
1 -131.000[R] KOG1763 Uncharacterized conserved protein, contains CCCH-type Zn-finger  ali  100  1MPPKKQAQAGGSKKADEKKKEKIIEDKTFGLKNKKGAKQQKFIKAVTHQVKFGQQNPRQVAQSEAEKKLKKDDKKKDLQELNELFKPVVAAQKISKGADPKSVVCAFFKQGQCTKGDKCKFSHDLTLERKCEKRSVYIDARDEELEKDTMDNWDEKKLEEVVNKKHGEAEKKKPKTQIVCKHFLEAIENNKYGWFWVCPGGGDICMYRHALPPGFVLKKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERRKADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGDEVDDSVSVNDIDLSLYIPRDVDETGITVASLERFSTYTSDKDENKLSEASGGRAENGERSDLEEDNEREGTGKWSH 397
2 -74.700[R] COG5252 Uncharacterized conserved protein, contains CCCH-type Zn-finger protein  ali follow..  39  57MPPKKG------KQAQAAGKKKDNVDKTFGMKNKNRSKVQKYIKQVQSQSDPKKEEMRLKKLEEKKRREAEEAERRA-------LFNPVADQRVRAGVDPKSMVCALFKLGNCNKGAKCKFSHDLNVGRRMEKKDLYQDTRSE-KENDTMDNWDEEKLRKVILSKHGNPK---TTTDKVCKYFIEAVENGKYGWFWICPNGGDKCMYRHSLPEGFVLKTNEQKREKQPKITLEEFIETERGKLDKKLTPITIANFAQWKKDHVIAKINAEKKLSSKRKPTGREIILKMSAENKSFETDNADMPDDVTQGDLTEFTDALKKADHQDDGGIKDYGDGSNPTFDIKKANSATLA.............................................. 401
3 -19.300[R] COG5063 CCCH-type Zn-finger protein  ali follow..  17  171....................................................................................................KTELCESFLKGSCPYGSKCQFAHGLGELKVKKSCKNFRTK--------------------------------------PCVNWEKL----------YCPYG-RRCCFKHGDDNDIAVYVKAGTYCNVSSTSKQSDEKRSNGRGSAKKKNLNVKV-MTW........................................................................................................................................... 285
4 -18.000[K] KOG2494 C3H1-type Zn-finger protein  ali follow..  26  1........................................................................................MTAVNVALIRDTTLEVCREFQRGTCSRADDCKFAHPPRVCHVENGR--------------------------------------------ACFDSLKG----------RCTR--ENCKYLHP........................................................................................................................................................................................... 72
5 -18.000[O] KOG1039 Predicted E3 ubiquitin ligase  ali follow..  33  1.................................................................................................MSTKQITCRYFMHGVCREGSQCLFSHDLANSKPST----------------------------------------------ICKYYQKG----------YCAYG-TRCRYDHTRPS........................................................................................................................................................................................ 59
6 -16.500[R] COG5084 Cleavage and polyadenylation specificity factor (CPSF) Clipper subunit and related makorin family Zn-finger proteins  ali follow..  17  115...QARKANLESYRAKLEKEYKTLAENKIQQRLSDGTKQLVTIDGLQYITGVSDTKWLEFVSAKGQCPKYLYWNNKSYLLKKKRFLKEVGNSP-------SAVYCRYYANGICGKGAACRFVHEPTRKTNKAEDCNLSHELDPRRIPACRYFLLGKCNNPNCRYVHIHYSENAP----ICFEFA------KYGF---CELG-TSCKNQHILQ......................................................................................................................................................................................... 313
7 -14.800[S] KOG4791 Uncharacterized conserved protein  ali follow..  38  8........................................................................................................CYFFFYSTCTKGDSCPFRHCEAALGN----------------------------------------------ETVCTLWQEG----------RCFR--RVCRFRH............................................................................................................................................................................................ 54
8 -7.930[R] KOG1312 DHHC-type Zn-finger proteins  ali follow..  12  139........................................................................................................CRIVKSKHCSICNRCVADHH-------------------------------------------------------CIWINNCIGKGNYLQFYL-------MCYAFLRLWYISLNSTSTLPRAV--IICAIFTYLQLAIVKEGMT--TNEQD-KWYTIQEYMREGKLVRSLDDDCPSWFFKCTEQKDDAAEPLQDQHVTFYSTNAYDHKHYNLTHYITIKDASEIPNIYDKGTFLANLTD...................................................... 334
9 -6.850[K] KOG2169 Zn-finger transcription factor  ali follow..  11  306FPLQLPNVIPTNKTNAEPKRPSRPVNITSNMNRYKKADKRVWADILFKRLNQNVSRHRSLEVTKQEVIKKLSGGEDDIAMDRLNI----------------SLLDPLCKT----RCQDCT--H------------------------------------------------------LQCLSYLMMNEKKP----WQCP-----C----------------SSNCPYDRLIVDDYFLDMLAKVDKNTTEVELKEDGSYDVIKEEAFCISDDDDDDVVPATVNGTASCSSTNGNGLA-NEAAKKKPADDDIITLSDDDDEELNRGIMNSLNDSFSPGRHTASAELAAQKTPPQQKKKTKDDDIEIITLDDTPPRPVAASANLPMRQMSQQNQMP.... 638
10 -6.840[S] COG5202 Predicted membrane protein  ali follow..  11  146...PSSELSSYQKDRALRKIPNILYFLGYSLLVGPAFDYVDYERFITLSMF------KPLADPYEKQITPHSLEPALGRCWRGLLWLILFITGSSI-ITAFVARMKYYGAWELSDG--SGIGYNGLDSSKHPRWDRVKNIDPIKFEKCALEAWNMNTLRNYVYLRVAKKGKRPGFKSTLSTFTVSAM--------W------------HGVSAGYYLRRHVRPFFLKPDMETPGPFKRVYDVIGMVATNLSLESIHVWKESKLDNKIRSRVNSYKLKSYEQSMKSTSDTDMLNMSVPKREDFENDE........................................................................................... 509

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.