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KOG1043
Query: [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLRYASNAYHIGRYAQRLFATGQRNRVFHQYIASTSLQTTSLRYASTDRSKVEYTLKMLREDVQKQDEEAQKVLSLMKSDKDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTVSDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKFLQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNLSMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACRARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLYLPEEVSFPDRLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKRLRHKLNSMIEDVDSMVDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAKLKESKGEQADDGEQRERIEALLKTIDEDSDGIVDKQLVLEVIELLEKHTDVHVSAAQMASMIGTLKKEDEVAGLTEEIRKVQSGNYQMPILPTGPSSADAFNQPQGVYTASKQVPARSEQEGVEQKQQVENGPVGIPDVDTKVTSTLQQNSSKTSSSSTTKSTSDSKSALast
1 -132.000[S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7  ali  100  1MSLRYASNAYHIGRYAQRLFATGQRNRVFHQYIASTSLQTTSLRYASTDRSKVEYTLKMLREDVQKQDEEAQKVLSLMKSDKDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTVSDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKFLQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNLSMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACRARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLYLPEEVSFPDRLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKRLRHKLNSMIEDVDSMVDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAKLKESKGEQADDGEQRERIEALLKTIDEDSDGIVDKQLVLEVIELLEKHTDVHVSAAQMASMIGTLKKEDEVAGLTEEIRKVQSGNYQMPILPTGPSSADAFNQPQGVYTASKQVPARSEQEGVEQKQQVENGPVGIPDVDTKVTSTLQQNSSKTSSSSTTKSTSDSKSA 784
2 -66.700[T] KOG4263 Putative receptor CCR1  ali follow..  16  91.................................SSSSSTQPTPSKKPEDEKRKELDTVKSKRDQMRDNMQDYIFTRYFNYVKNYDKVLEKNFPKAMQLYRVFFDGVKDFFGDMKRFLKIARIANDSRALNRQELELYMQMPRDMMKVAPALIGCSLPMVGYAFFPLVFYYRSFLTAHFWTPQQRSEFQSYYMKRRLCNNKDVFRCLQDKL----KATASHPKHSAFADILGQLGS-GTHPTPEMLIDVKDIFAEPYSLLGMSRKHVRNLVNLHGLP---SSIFKRHRLHEHAFLVHYMDQAITREGGVHNLTPDALRYSCYLRGLNPDSLSSEAMIEWLRKWVKVSTSIQGEHITLFLHLPILLGYNHPNNWKT.......................................................................................................................................................................................................................................................................................................................................................................................................................... 429
3 -19.200[R] KOG0431 Auxilin-like protein and related proteins containing DnaJ domain  ali follow..  444......................................................................................................................................................................................................................................................................................................................................................................................GEDSDVFSTAAASAAAMKDAMDKAEAKFRHAKERREKENLKASRSREGDHTENYDSRERELREKQVRLDRERAEREAEMEKAQEREKEEREREQKRIERERERLVARQAVERATREARERAATEAHAKVQRAAVGKATDARERAERAAVQRAHAEARERAAAGARDKAAKAAAEAREKAEKAAAEAKERANAEAREKETRVRAERAAVERAAAEARGRAAAQAKAKQQQENTNDLDSFFSSISRPNSAPRQRTNPLDPFQDSWNKGGSFESSRESLRVPPGQPENLRKTSSVTNIVDDLSSIISELPNLVGFKMLMEKLKRDDVPDWNATRGHRSGLQKHLLRKMNVIFKYKENKLRKIGSVIFLFNHHAYPGFQRIGVLDVEIKRWGAGKEGNLRALLSTLQ....... 852
4 -18.800[S] KOG4360 Uncharacterized coiled coil protein  ali follow..  3................................................................................................................................................................................................................................................................................................................................................................................QSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHILSEQNEEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDELRETNAQMSRMTEELSGKSDELIRYQEELSSLLS------------QIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAF-TGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRS 418
5 -18.500[S] KOG2216 Conserved coiled/coiled coil protein  ali follow..  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................EDGEIEEGMVTADEFPTPEVTTIETIQPPREPGKSPLELLRESKTSVEEIVAKMLSMKKQGNHK--SEIRELLTQMFLNFVNLRQANRAILTEEDKVKAEERAKAPVDFTTLQLHNLMYEKSHYVKAIKACRDFKSKYPDIDLVPEQDFFRHAPEAIKDQSSSHVLMPKRLNFELHQRKELCKHRARLEQQKK-SLLETIAERKKFLSSLPLHLKSLKKASLPVQNHLGIQHTKKLKQHNLAELLPPPLYVLYSQLLAQKEAFEESIELEVVGSLKDAQAYARQQSRKDSGMSSNTESSRLEDDGPDDDDDGQRRRKRPKKLTSKEGSDKAG 335
6 -18.400[D] COG5185 Protein involved in chromosome segregation, interacts with SMC proteins  ali follow..  11  236..............................................................................................................................................................................................................................................................................................................................................................................................DYLVRTYHLYLDESPEESEPEKELKATFNQQNQDLYNQTEALKSTNEELINQIKSAEE-----LDSAIQVLEERYRTMQRDEVKFQSAMSGMKSKMESRTNLMKQLQVNIEEKESQLQLLKEKRDSLKYQVENQDIS--ISEFEKMVSEREQLDRNLNMIGSKISELRKE--VFDTDLLIQASIDSLEKKVQKFNSLAYRIGIVPIAAIRSANNDFELEINPEGPNYINLDLKNKVRPFINEVRRSITLEFHEEQNKSLKLQEHVDTVND-----LIAELQDELRGIESRLTSVLSECNMLRETASEEKNAFDAESDKLERELQQLKLSSHNSDQRIQSINIEADQIAHACMEYKNNIYKEVAFVLGEIIHFKLHVQDSLEDLKMDYQKELDDLSRSE.... 623
7 -18.300[D] COG5244 Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B  ali follow..  259..............................................................................................................................................................................................................................................................................................................................................................................................NFRREKFLKKFLAMQKEIKYLRKRKLQIRKIPNYKYSDRSLNSKTPKSQDNWTTQVTPSSLLGVSEVSKV--LQLKQVQVDITELVKIPKNPFSEKLTISNVNRYLNIVPGSLDLQFSLTNENFVHWNSTVYQELLNLKSKTRRQLLEENALLSHKVLKLTEEIQDLETNQLNTEIEARQSEKLNEVQEETQRLSQLLISSQPALTEVKHLKLC---SDSQEELLQLNAKLEKANIVIDELNSAKLKSKQVEEESSMKDDLTEMNQRLKEQIESYENEVNSEITSRTLKEFETLKTQYEKNLCNLREQLKTARMKLADKYPQGDNTSENIDWLKHSLRDSNTENSSPLTFACKEIRKLVADIKPVSVEKQLALNWKKDIERPSFHHNQQLFNYCQLTDI... 665
8 -18.300[S] KOG1103 Predicted coiled-coil protein  ali follow..  5..................................................................................................................................................................................................................................................................................................................................................................................................................................................................LDDSFDPTFQSTSKKLVLPSIRKVQPEYDNLPEEQGVNDFSSDELMKLLSFMEGEVQAREDVIDHLKRERTKILLSEAKYGKLNMNDPFAALRRDSAITGEQIDEEKIVQMYESQVDQLDKMMAVQKQSQRNAAVLLVAL--------EKKQYKLVKKLEADREAKIRYAKQGDDLVAHLEK-NQLQQQIEFHIEEKRKAEI-----AKDKMEMTLGNEKKRHESIVLYLIQERKQMLLKMHELRVKAEQIMLQNQNDPTKPPSSALSERELIEELKKEVTFLRAERESLTKTQKMVKTENLSLRETVRGQEADLQMLRRNLTLTGAKMSIDK. 326
9 -18.100[D] KOG0995 Centromere-associated protein HEC1  ali follow..  10  210..............................................................................................................................................................................................................................................................................................................................................................................................RDYTNDRKAAENPSSSYWDDTKHRLRKYFEQSNEFEDMTKTAASALEMLNYECDEIEADKGASLKEEISRIRDDIRKAKDYLEQNLHVKQHMEKELAMVKSEQEEKISENEKVQKMVDDLKNKIELQKQIHGGKEVRQMNLDNNKDKEVVLEIQSELDRLSKETWKLKDEDFFKEQKSKFIHLAEQIMKILSGLNIQMNLEPLRAPTNERDLKDYWETLNKIWVPEISRQLHQRKLELETEQSRFSNEERIQIQSETLCEAKKNEAREERIRR-----NERDSWKDARKHIEQRYEQLLNEKEVLLKQMKLDGSLEKEIEDETARMSATGEEHIQKRSQLEAGIRQILDLMVVEIAEIENKKIGFHVQCAGIEKAV.......................... 589
10 -17.900[YU] KOG4460 Nuclear pore complex, Nup88/rNup84 component  ali follow..  429...............................................................................................................................................................................................................................................................................................................................................................................................................................................................GSDEEDKDSLQELSTEQKCFVEHILCTRPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLST-VHPASPPLLCTREDVEVAESSLRVLAETPDSFEKH--IRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCDQKKK------QLEDLSYCREERKSLREMAERLADKYEEAKEKQED------MNRMKKLLHSFHSELPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF.......... 741
11 -17.600[T] KOG3759 Uncharacterized RUN domain protein  ali follow..  10  1........................................................................................................................................................................................................................................................................................................................................................................................................MEMKMAEAQETKDSCSTIEGQLPAGPVRAEDEEEEVEVEQEQQELLSE-RWSPLGANYDDANSASSGVDCELEPGLEKSEARRGSTGSELARLRSIEEEQELLTSSLLALTSHFAHVQLRVRQIVEAPAEE-----RDQLLRDLEDFAFQGIPDAVQSKESHPDKPASDGEKDHGPDSQLIQQLKSQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKLNLQVEQHELPALSTEQLRHQVDNAIGEFVGPLKMKE--------QLVAQLKTQITDLERFIAFLQCDAIEGSVGDRLKLAYNSYAAKQTARSSQASYVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKASVLMQMFASTHLVKPRTHDEFQQNSLKKTHKG. 380
12 -17.500[D] COG3096 Uncharacterized protein involved in chromosome partitioning  ali follow..  11  211..........................................................................................................................................................................................................................................................................................................................................................................................SAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALE-FRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQEKIERYEADLDELQIRLEEQNEVVAEAIERQQENEAREAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKEAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCK--RQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQD 627
13 -17.400[M] COG3264 Small-conductance mechanosensitive channel  ali follow..  3...................................................................................................................................................................................................................................................................................................................................................................LIITFLMAWCLSWGAYAATAPDSKQITQEL-EQAKAAKPAQPEVVEALQSALNALEERKGSLERIKQYQEVIDNYPKLSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSEAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVRQALNTLREQEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYL............... 429
14 -17.200[S] KOG0992 Uncharacterized conserved protein  ali follow..  14  121..................................................................................................................................................................................................................................................................................................................................................................................EAHFNVTTKEMSQKFNLALQQATKKAEQCDKEKNEAVVKYAMREGEMMKLRDEISKKDSNMKVIKEELEAARKAQSQENLDDLEKTVQNLKVEIEKLKHERFDFENRMKIAEKRVESLSSNLSESKQQGDMLRKQLIQAKDDKHQQYEVKLQTSTAELERRLRESEHDVERLRTSQLEMATKEEASRENTDLLSKIDILQDQLSLEEDRRKLCEEQIDRLKGVESFSSSHRIEETEKERETAEEDREQAELEAAEYREQVEKMLKLTQELTE------------RNMELQRKLKDEEGKNTSHNSTIEKLQVELTTSLELCKSFEETNLKISEELENLKTEMQKPVTLESLEENFYRDKYDEASRKLEQTEAKLAEEKNNFSAFKKKTSATLKELKSELSGYRKNNGAGDSGAA 527
15 -17.000[K] KOG0963 Transcription factor/CCAAT displacement protein CDP1  ali follow..  117..................................................................................................................................................................................................................................................................................................................................................................................................LKTQKQIEDLKKEKEEMEGSLQGKEKLEREVENLRKELDKYKDLVETEAEKRAAITKEECEKSWLEQQKLYKDMEQENASTIQKLTSKIRELQASQLDHDLQASQNESAGLDVNAKSAEVNAILSELDDKIIVELQAEIAVLKQNTKEQKSGSSQDDLSNQQKQQDSLNKKLSTELESIKEASRKEMETHCATIQTLENEVKEARKVEESLTLANKFSDYDEIKRELSVLKQIEFSGEHATHENTSLESQLLKREKQLSEELTNAQLTDRITQESKKSFLEQKASEQEEVIRKLEKDLADVDVEGSVYLSNTTYRREGTSGQLSPTSSIMGGNPSLFNGSVLSRNSVNETGSAIVDVIKQQRDRFRRANVTLVNQVSAANDKIALLESKLEEVEKSN. 526
16 -16.800[O] KOG0978 E3 ubiquitin ligase involved in syntaxin degradation  ali follow..  388..............................................................................................................................................................................................................................................................................................................................................................................................HHWNAELDRYKILTEAIQAERSFVMRRDKELNLRAESLEAANHKTTTVGSRIEVLEKKLQSCIIEKNGLELETEEAIQDSERQDIKSEFIAMASTLSKEMEMMEAQLKRWKDTAQDALYLREQAQSLRVSLSNDEQKGLEDKCAKQMAEIKSLKALIEKLLKEKLQLQNLASICTRECNDDRGLAEIKDSQRKAQAQAEELKNVLDEHFLELRVKAAHETESACQELATAKAEIAELRTQLDLSEREVLELKEGIKVKEQEAEAIAEMETIGQAYEDMQTQQHLLQQVAERDDYNIKLVSESVKTKHAYNTHLSEKQVMEKQLHQVNASVENFKARIAHNEEQMKSEAYKLIQEDRHLVISLETTKWEVADADKEFRWLKSAVSSSEKEYEQISRRTDDIKL 797
17 -16.800[L] COG0419 ATPase involved in DNA repair  ali follow..  108...................................................................................................................................................................................................................................................................................................................................................................................ELLDKRLSETKTEL-SDLQGDLQGLDIRKDEIQSELDTLYLRRANLEKLQLLVKDISNLEEEIRTIDRETEVLRIELPSSIAHHNLDEIYAEREKLLEKRGYLRKQIERTKLEETSFKKKIDDAVLANNEQKLKLTKLNFQVNE--LEQLEKDINKSSEDCDLQKKKLLEVSSKQGSQAPFSEYEKLEADIQEMAQKSRTEILEANEYLHQLNEWNSEL-RIDVSTKFKCIKEKKSNIGEEVRIIASKIESTDDNLRKLQERLADLRTRERNASDNLRLRALMRQLEEAVTQKN-YLLSQQSHDDRESFRERMQILKSKYGALNAERAGLLGECKQLENSITKDKEELNMEFKDADERFRRQLIKTKTTGKANEDLGKYAKALDVAIMQLHSMKMNEINR............. 507
18 -16.700[D] KOG4593 Mitotic checkpoint protein MAD1  ali follow..  64..............................................................................................................................................................................................................................................................................................................................................................................................QMVKADVLDALSTAEKQVEESKTKLQTLNANFTEADAERKHFRDKFLYSEQEAKAREKMLQEQLLMEINNSQERYTKELQSCHELEVKLQNEMNLRKKAESSAATAEEKAKLLEDKLTQLSGSVDREKKRLNNQLGKEAKLSVARIGADLERMQCRAQNAETESNLLRSQEHLKLIFDECLQEKTEVDKKLSSFTSEAASSSDNSVLVKHQEELKRYEAEVREARKLKSRHLDAELLNVNLLEEQSRRERAESELSKFHDLQLSMEKLENELSSWKSLLNDIPGVSCPDDIVMRFSVLQNEVVQSTMKIGEASTRIKQLEETLEAIQLGRQNAVSEAALAKEKLKTDVKRIEVMLTLVTEEKEQLKAVVNELRKSNSEGSVSGAADGALIQGFESSLAKKEN 476
19 -16.700[D] KOG4438 Centromere-associated protein NUF2  ali follow..  10  131..............................................................................................................................................................................................................................................................................................................................................................................................................................................................REACRETYMEFLWQYKSSADKMQQLNAAHQEALMKLERLDSVPVEEQEEFKQLSDGIQELQQSLNQDFHQKTIVLQEGNSQKKSNISEKTKRLNELKLLVVSLKEIQ--ESLKTKIVDSPEKLKNYKEKMKDTVQKLKNARQEVVEEIYGDSVDCLPSCQLEVQLYQKKIQDLSDNREKLASILKESLNLEDQIESDESELKKLKT-----EENSFKRLMIVKKEKLATAQFKINKKHEDVKQYKRTVIEDCNKVQEKRGAVYERVTTINQEIQKIKLGIQQLKDAAEREKLKSQEIFLNLKTALEKYHDGIEKAAEDSYAKIDEKTAELKRKMFK.. 461
20 -16.600[U] KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport  ali follow..  12  528..............................................................................................................................................................................................................................................................................................................................................................................................AGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTA-EEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAMEKVKQEESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEE 944
21 -16.500[DZ] KOG4302 Microtubule-associated protein essential for anaphase spindle elongation  ali follow..  3...................................................................................................................................................................................................................................................................................................................................................................................................EIGSPNALFFRTNTTCNNLLRELQKIWVEIGETETEKDRMLMELERECLQIYQRKVDEAANSKAKLHQSVASIEAEVASLMAALGVLNINSPIKLD------KGSKSLKEKLAAVTPLVEELRIQKEEKQFSDIKAQIEKISGEISGYSDHLNKAMNISLTLEEQDLTLRNLNEYQTHLRTLQKEKSDRLNKVLGYVNEVHALCGVLGVDFSQTSDSTLEGLEHMIQKLKTERKSRFQKLKDVASLFELWNLMDTPQEDRTKFGKVTYVVRSSEANEPGILSTETIEQVSTEVDSLSKLKASRMKELVMKRRSELEDLCRLTHIQPDTSTSAEKSTALIDSGLVDPSELLANIEMQINKIKDEAQSRKDIMDRIDRWLSACEEENWLEEYNLDENR. 416
22 -16.500[M] KOG1854 Mitochondrial inner membrane protein (mitofilin)  ali follow..  170..........................................................................................................................................................................................................................................................................................................................................................................................APLPPVLPREPTHVDPVDVRKDVTPMIPKPSPDVVFAKNQQLEEKLKIAIHSAEGKVRLATEAKLKTINAINEHASILKQTVDDAKHANWENVTSALQRAEAEARVDSGQEVDGRNYIDNLRKIVNDGKRDSTTATNPLLLNAQETANKLSHQLDEINALVNKSRQESAVLNQEKSRQQFALEMKSILPNVDIHAKDKNLNEDELNALIAHAHLKVDQLRCQLSDQQVREELHISKALEEQRLADERIASEKLSIEMSRVGRQNELEIERALVESRSSWEGELENQLKRTASAHSEHLEQVIRTQRQLFEIEQNQKVEEAVLQERNLHSKQVGAALSRLEGIEEALGSRVALDNENRRAKQFWIACHNLIDTLKHGNKAGNNIDERRLPLNESLNLLKEVNPEDE. 579
23 -16.300[KT] KOG3667 STAT protein  ali follow..  1..................................................................................................................................................................................................................................................................................................................................................MAQWNQL--------------------------QQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDV-RKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQ---SVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN 420
24 -16.200[R] KOG1899 LAR transmembrane tyrosine phosphatase-interacting protein liprin  ali follow..  10  1............................................................................................................................................................................................................................................................................................................................................................................................MASDASHALEAALEQMDGIIAGTKTGADLSDGTCEPGLASPASYMNPFPVLHLIEDLRLALEMLELPQERAALLSQIPGPTAA-----YIKEWFEESLSQVNHHSAASNETYQERLARLEGDKESLILQVSVLTDQ-VEAQGEKIRDLEVCLEGHQVKLNAAEEMQQELLSRTSLETQKLDLMTEVSELKLKLVGMEKEQREQEEKQRKAEELL------------QELRHLKIKVEELENERNQYEWKLKATKAEVAQLQEQVALKDAEIERLHS-QLSRTAALHSESHTERDQEIQRLKMGMETLLLANEDKDRRIEELTGLLNQYRKVKEIVMVTQGPSERTLSINEEEPEGGFSKWNATNKDPEELFKQEMPPRCSSPTVGPPPLPQKSLETRAQKKLSC 386
25 -16.200[S] KOG2701 Uncharacterized conserved protein  ali follow..  10  172..................................................................................................................................................................................................................................................................................................................................................................................................PAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTETYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPP-GTLTSAMTHDEDLDRRYNMEKEKLYKIRLLARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS 575
26 -16.100[UR] KOG4677 Golgi integral membrane protein  ali follow..  3.....................................................................................................................................................................................................................................................................................................................................................WLDIAGAAE------LLNKLDEKTGDAIQNARDSAPRTRKSSTASVSATIISMPEHVITEDFGRPAPSLPSRAQSDYTGAGWRGGRNYEQGSSSTHQPGVTAASESWTMVLNSKEVKNAKPDEDTRSQRSVGGRSVASIRTTSEFAGNDSSPNFKSQLFAKDSQISVLKTKLSERKFEKRSQDYYEMKAEKEMLEKRVENQKVSSHEMDSLQELKLARQKAQDQKEKAVEECNMHKRKIVGLEEEIRAMV--------EQLRLAKFNLNENKKEFDEYKNKAQKILTAKEKLVESLKSEQGIGSSDRPVHLLQAEVEEIRVE--RDLTKADLESAQLQVYTLRSDMEELEAQIRDLQSQLSDQKRTHLEEKQTWDSTIGLLNEKVECSRIENEFTKQEMKRQGDQHQSKMLEKENELRKTISDLRSRMRDEQTKQEDDGSSQ. 435
27 -16.000[T] KOG3872 FOG: FHA domain  ali follow..  219.........................................................................................................................................................................................................................................................................................................DSRVLSRNHACLSCDPTSIRDLKSSNGVNGVKIRQNDVE--LKV-VDLGTDIDSKFEHRKISAYVEEISVIPLMNTVSDPTNLVMKKQDHTNKNNGNSTNINGIKIDRGHHNQHIPIRSHLKENYTEAGVTSATTAQRAAFEAAMFGDINNSELDDDILGPETEVLSGIFINNSAGTSINLINMIKTLTTELSLEKQELEKLH-------------------SMQNFMQNYTINLDFINKHMIDMNEKHLLKLSTALQKTLSENNDALLKESEDQLKEIKQQNNKVKSACSL--------KEKQNHEKLQELESELRELNLQIEEERG-----------------------------KNLVLTQSNFNGGINNDNNAKVKQNDSREEKKDTEDTLISTEELGVVEGKRTRVSKGMLFGVVAIS................................................................ 591
28 -15.800[Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting protein Hip1  ali follow..  10  311................................................................................................................................................................................................................................................................................................................................................................................AEAEPQQASPSSQPDPREEQIVMLSRAVEDEKFAKERLIQEARSRIEQYENRLLQMQGEFDHAKREADENREEAQRLKNELALRDASRTQTDDARVKEAELKATAAEERFNKMKGVYEKFRSEHVLALTKLGDIQKQLEASEKSKFDEEITALNRKVEEAQREAGRALTKAEGDAGAVDEMRTQ--LVKADIEVEELKRTIDHLRESHANQLVQSSAEETNKIRLAELEVAKESGVGITQMFDHCEDLQNATSITYPPHLAQSAMNNLVNILSNERKDNVFAGHLLSTTLSAAASAAYTASIESYEGVNDQCKKAAAKVAFSDDSALSRADKMKLLRQDIQTLNSLMISLPLQTDIDKDVVGNELEQEMRRMDDAIRRAVQEIEAIQRRARESSDGIRLEVNESILANCQALMSV. 735
29 -15.800[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  554..................................................................................................................................................................................................................................................................................................................................................................................................NSLESYMKEKLKQLIEKRIGKENFIEKLGFISKHELYSRASQKPQPNFPSPEYMIFDHEFTKLVKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTLKCQNEQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGGIQPEEIGRLREEIEELKRNQELLQSQLTEKDSMIENMKSSNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAK-----SVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITDSKKEQDDLLADQDQKILSLKNKLKDLGHPVEEEDELESGDQEDEDDESEDPGKD.. 958
30 -15.800[R] KOG2295 C2H2 Zn-finger protein  ali follow..  165..................................................................................................................................................................................................................................................................................................................................................................................................QDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEA-EKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSSI---LRNLAPSITR--SEIEAVCNR.................... 537
31 -15.700[S] COG4913 Uncharacterized protein conserved in bacteria  ali follow..  276................................................................................................................................................................................................................................................................................................................................................................................DDVQKHQTQLASIQALEAGRDTLRPYFAQLKGELLKHRLDALAAEAAQLTVEIQHLEEQRKAADSEVTQLRQALRDNGGDRLEELAAEIEQLEQAKAQRQKKSDRYQTLLTKIDETAPADAIGFLTQQQRFAQHTEELNAAIERLHND-KSEKDRALYDAREKHTTLLAEINSLQQRQSNISAAQIRIRLGWSNADKLHTLNAQRQHLEDSMGMLGQDIGTIQREC-----QKQQERLDALNKLGEYPEFADIDWMSLVRQIAGRKKEQEQLQATSNILQTLQQ--QLTAAQTQVSVLERKCKNAWHEQGEVKSQQKTAQQMWNQARSVWDDAPLSQAQITLLAGWRQQALGEHVLSVESCDNHEQQVRQWLQKRIDAENAHLRQLNDRITGAMHRFKNQFKAETVEMDADLAALP 843
32 -15.700[R] KOG4403 Cell surface glycoprotein STIM, contains SAM domain  ali follow..  11  61..................................................................................................................................................................................................................................................................EKLSFEAVRNIHKLMDVDVEESDEFLREDLNVKHSTFHGEDKLI---------SVEDLWKAWKSSEVYNWTVDE------VVQWLITYVE---------------LPQYEETFRKLQLSGHAMPRLAVTNTTMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVHLEKKLRDEINLAKQEAQRLKELREGTENERSRQKY-----AEEELEQVREALRKAEKELESHSSWYAPEALQKWLQ---LTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTAALRERLHRWQQIEILCGFQIVNNPGIHSLVALNIDPSWMGSTRPNPAHFIMTDDVDDMDEEIVSPLSMQSPSLQSSVRQRLTEPQHGLGSQRDLTHSDSESSLHMSDRQRVAPKPPQMSRAADEALNAMTSNGSHRLIEGVHPGSLVEKLPDSPAL 578
33 -15.500[K] KOG3915 Transcription regulator dachshund, contains SKI/SNO domain  ali follow..  429.................................................................................................................................................................................................................................................................................................................................................................................................TSVIKERVPDSPSPAPSLEEGRRPGSHPSSHRSSSVSSSPARTESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPKEGDLAGHDMGHESKRMHIEKDETPLSTPTARDSLDKLSLTGHGQPLPPGFP-----SPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQLEK--TELKMDFLRERELRETLEKQLAMEQKNRAIVQ---------------KRLKKEKKAKRKLQEALEFETKRREQAEQTLKQAASTDSLRVLNDSLTPEIEADRSGGRTD-AERTIQDGRLYLKTT..................................................................................................... 703
34 -15.300[Z] KOG2685 Cystoskeletal protein Tektin  ali follow..  85............................................................................................................................................................................................................................................................................................................................................................................................................DYNNKIKFRITCDQEKLAERIVEESRRVVDETKDTTKNWQREVEHHMRERTSEIRFLVDELNRQKKTAALEDEALNTYRNRVLNCIEFLKDKSLAICKQCLILREGRIGVDLCDDEVDRS-----RRELKVIKGCQGLADAALKEAEEQIRKLRAAIYLLDQDLAAKDKSLAIDEKNLKLKEFQHDLAKGQDLSKQHCQFSLTEWQAQTYENLEANAKALVSAGQLRAYIDLLLKQVCEDMQNQTDRTNEAFE----RRISETKHVKQCLENKHKDTMDHIHQVQRNMTELEKEMMDKQRAITLCQTRL-SNRAHRPGLELTCDMVQDALYNELQALKASVCKLNQKLNENKASMRYLMHVQVMQEEEINIKANTCKIDEVDCMT... 460
35 -15.300[A] KOG4849 mRNA cleavage factor I subunit/CPSF subunit  ali follow..  449..............................................................................................................................................................................................................................................................................................................................................................................................EEVMSRNRTVSSSAIARAVSDAAAGEYSSAIETLVTAISLIKQSKVAHDERCKILISSLQDTLHGIEAKSYNRRERSRSRERSHRSRQRRERSTSRYRERSRERERDRDRERERDGGRSVRPRKSPEPVVAEAAEAPSSKRYYEDRERYRSSDRERRDRDRDRDRERERDRDRHFTNDGRGLPLDPSNFTSQNPGNIKTGRPKSAAVAGGSMEKPRGQSAWDIIDTDAHWIIKQQTTSIPAPPSSQQNFNIIVL.................................................................................................................................................... 702
36 -15.100[S] KOG3850 Predicted membrane protein  ali follow..  52....................................................................................................................................................................................................................................................................................................................................................................................................................................LAEEAEGIGDKVDKGDLVALSLPAGHGDTDGPISLDVPDGAPDPQRTKAAIDHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHTAVVSKPREFASLIRNKFGSADNIAHLKDPLEDGARALSGSATLVSSPKYGSDDECSSASASSAGASNALYGAPGNLDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAERARDIQEAVESCLTRVTKLELQQQQQQVVQ. 443
37 -15.100[S] COG4372 Uncharacterized protein conserved in bacteria with the myosin-like domain  ali follow..  19..............................................................................................................................................................................................................................................................................................................................................................................................AALGDHLGSKVGKARLRLFKLRPRQTAVLLTVITGTLISASTLGILFTFSKSLREGVF-QLDDILAQLRVAKTELEQASQAKEEIESELTAVREEQQLVQERSRELNRNYTKALQLLRRVSEQSRNLRQEVANAERAQLNEQKDSLLAESSELQSQVKLRDQELSKRQERAQQEKVLARQREQVQSLEKRFASLEAQRQQLQAEINQR-DTKIDQLDQAIAAKDNDIQAREEKLQGLETELSFLQREVEELERYYQDYQELRGQQIAILRGQLLAFGGLRVVSSEAVTGAVDQLLRQANRTALQLVKTPNMPVPDEPIVRVTTAQVDSITSQLQPGQEYVIRVLSAGNYVQEEREIRVFFDVVPNRQVFREAETIATISLESSDFSEVDVQKRIDYLLAAA. 420
38 -15.000[R] KOG0804 Cytoplasmic Zn-finger protein BRAP2 (BRCA1 associated protein)  ali follow..  343..............................................................................................................................................................................................................................................................................................................................................................................................ELTSHTYSLKVGGERVWDYAGDNYVHRLIENGADGKLVEYQRESNASFDDKNQKGGDKLEGIKLEYTLLLTSQLEDQRKYFEGLRHDMEQTMSKMEKTAYAQVENLEHQLTERSTELKSLKGDLDDTVTARKEKRATQTNEKVNKLANELKDEREINQMLRKDQQVWKGQ--VEKLIESQKTARTEYEKKIEDLQSQVNDLLMHFETQNKLK--EQLDAGKITQEEITESQVELDSSSSSSRKLNRKKKK........................................................................................................................................................ 590
39 -15.000[S] COG1511 Predicted membrane protein  ali follow..  1...................................................................................................................................................................................................................................................................................................MNTIRSQWKDIVTS--VPLITVDQLPVVVQDKGATYEGEK-DDLVKELKDWHFSNDLDQSLKDL-FSKNASTVLDKNPKKLDLKYHTNAGSNYVGATIGEKAIDKLKASVSKEVTEQYTKVIFDNFKDIAKGLSDASSGAKKIDDGTKDAKNAQLKENLAKLKESTATISDKTAQLADGAAQVTSGIQSLDSSLGKFQDSSNQIYDKSSQLAAGSGELTSKMNEAGLQNVQKGTPNLTNGLDQLNSKVQEGSEKAAKAEKNALDLTKLETAVNNLEKSETAMKEFKKQLTDFENSLKNRDQAFKNVINSSDFLTAEQKSQLINSVEKKLPQVDAPDFDQILSQLPTADQLPDIATIKSSLE--DVKAQVAQVKAMPEATSKLYNGAKTIQDAIDRLTEGADKIYNGSQKLTDGQTKLTAGIGEYNKQFAKAKAGSEQL-VTGSSQVSGGLFKLLDGSKQVQSGSSKLADGSASLDTGLGKLLDGTGELSSKLK 543
40 -14.900[S] KOG4725 Uncharacterized conserved protein  ali follow..  3..............................................................................................................................................................................................................................................................................................................................................................................EETQQSKLAAAKKKLKEWQRNSPGVPAGAERNRKTNGSGPETATSGGGHSPGDSAPGVHGEGPTSSATLKDLESPCQEPAVVPDSRSVKISQLKNTIKSLEKKANNEKQKAERELEVQIQRLNTQKGKLNMDLYHTKRSLKYFEDESKGIRLQHSLQRIAELERALFAVTTTQEKKEDSVHTLKKEKYETHRGEKLERSLSKLKNQMAEPLLPEPPGVPSEVELQHKEVERVAAELQAQVDNNKRMSVLILGQKERLQEQDERLREQDARPQQLAEPQSSFEELNKNKSALQLEQQVEELQEKLGEVELKSREAQSLQQHPDYYLGHLQQYVATCQEQVAAYQQLTSEEALHSQLLQQTQLMNQLHQQEARGKAIADLARQNQQNQPLQAQLSLMALPGEGDGGGHLDSEEEEAPRP. 424
41 -14.900[U] KOG0993 Rab5 GTPase effector Rabaptin-5  ali follow..  484..............................................................................................................................................................................................................................................................................................................................................................................................EETASLLSSVTQGMESAYVSPSGYRLVSETEWNLLQKEVHNAGNKLGRRCDMCSNYEK-QLQGIQIQEAETRDQVKKLQLMLRQANDQLEKTMKDKQELEDFIKQSSEDSSHQISALVLRAQASEILLEELQSQAKRDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKH--SLHVSLQQAEDFILPDTTEALRELVLKYREDIINVR--------TAADHVEEKLKAEILFLKEQIQAEQCLKENLEE--TLQLEIENCKEEIASISSLKAELERIKVEGQLESTLREKSQQLESLQEIKISLEEQLKKETAAKATVEQLMFEEKNKAQRLQTELDVSEQVQRDF----VKLSQTLQVQLERIRQADSLERIRAILNDTKLTDINQLPET.......... 862
42 -14.800[R] KOG2135 Proteins containing the RNA recognition motif  ali follow..  10  371..................................................................................................................................................................................................................................................................................................................................AKIPPEMNTIAKLNEHFATFIQVRYNGEIDSALVTYASKFDAGKAYKSPTPVGGEGSENATGKPSSPTSPPKPVEKPKIATVQESKFVSVAAQNYRKQIQDAKERLTKEKSILSTLVQAQNQHNIILDKWMVKQKELLIKRTSTDETDKKNATKLVKHLHKKIKACKEEVDGILLKISEKSMVVDEIAAQIEELKNPQKSDDSTRKRKAGSDGDEPQSKMSSVVIVRGVTDELVTDLMAHMEKFGEVFDHSVKADDDGLITAVFPFRKTGDALKAMADGKVLNGVDLEELKTERIEEIPSTDTNMSADQLLAAIPSNLESDEEDDLLND..................................................................................................................................... 719
43 -14.500[Z] KOG1850 Myosin-like coiled-coil protein  ali follow..  164..................................................................................................................................................................................................................................................................................................................................................................................................ADLLEESRSVQKQMKILQKKQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATAHFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHI-DKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKE--ATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTT--AKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKT------------VRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQVSIKAAIKAANRDLATPVMQPCTALDSHKELN----TSSKRALGAHLEAEPKSQRSAVQKPPSTGSAPAIESVD............. 528
44 -14.500[S] COG4694 Uncharacterized protein conserved in bacteria  ali follow..  33...................................................................................................................................................................................................................................................................................................................................GWNGTGKS--TLSNLFSCFELRSMVPRFSAGQFSVALEDGSTITEATLHSCQLNIHVFNQRFVHENIDWDKSVKSILLIAKEKIDDLQKLEK-LKGELQSKRKARDEKQGEVKKQREALDKFLTNAAKKMKLGLQAIDTSDSYYLNYDRRKLSNFIQSNGEAIIKADSILSDDKVIDLTNAAKPDQLPSINFVSTSIEPDYFKKASGRIRDLIGTTAVNQAIQRLTDNPDIREWVQTGLEIHKNHESQS-STFTQLRAEALAAHFSKEFTDFQRRLQNAATWIESQGAPANQLPAATEFYKELSAEADKLQKDYATAAEKIDKQMDGWREALKAKITDPGKTDIQISDVVEDDVKNFNEILKSIVALVGKHNNKTSNFKSETSKSKVALELHFAAAE----VQEFDYAGSEKKCNDLESEAKNDHKEIEKISQEVGAIEALLSNETVGAKEFNDILHR... 487
45 -14.400[A] KOG0152 Spliceosomal protein FBP11/Splicing factor PRP40  ali follow..  404..........................................................................................................................................................................................................................................................................................................................................AKAAFKSLLESW---------EQTLKEIVHDKRYGALRTLGERKQAFNEYLGQRKKVEAEERRRRQKKAREEFVKMLEECEELSSSLKWSKAMSLFENDQRFKAVDRPRDREDLFDNYIVELERKEREKAAEEHRQYMADYRKFLETCDYIKAGTQDDRCSCLEKIDRLIGFEEYILDLEKEEEELKRVEKEHVRRAERKNRDAFRTLLEEHVAAGINTSGSTPKDLFEDVTEELEKQYHEDKSYVKDAMKSRKANFKSAISEDLSTQQISDINLKLIYDDLVGRVKEKEEKEARKLQRLAEEFTNLLHTFKEITVASNWEDSKQLVEESQEYRSIGDESVSQGLFEEYITSLQEKAKEKERKRDEEKVRKEKERDEKEKRKDKDKERREKEREREKEKGKERSKREESDGETAMDVSEGHKDEKRKGKDRDRKHRRRHHNNSDEDVSSDRDD. 890
46 -14.300[S] COG5293 Uncharacterized protein conserved in bacteria  ali follow..  10  161.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................GRDAFSTPFEHHKNQLSWEKQINNSFLLGLAWEDARELQLLNDKQKLITDIKKLKKDTESGVAIGILGSLGELEALKVQVEAQLRERKETLNNFRVAEQ----YHELEERVNFLTSQIHEATNKNITDQKLLEFYQS----SLKSEDEPRPDDIVSIYENAGIELPG--LVVRRLEEVEIFHRRLIENRREFLGSEIKRLRRDLVSRENFIREKSNERAELLEVLKTHGALEEYTMLQEIYLDNVANNEINKRIEELKQFEEERSSLKIEKELLLQRARRDYGERNEQAERAIDLFRINSRFLYDTPGRLIIDVGKNGFT......... 471
47 -14.200[U] KOG0999 Microtubule-associated protein Bicaudal-D  ali follow..  2..............................................................................................................................................................................................................................................................................................................................................................................................SAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTN-----TQSENERLASVAQELKEINQNVEIQRGRLRDDKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDDAAEPNNDAEALVNGFEHGGLAKLPLDNKTSTPKKEGLAPPSPSLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKER 406
48 -14.200[J] KOG2147 Nucleolar protein involved in 40S ribosome biogenesis  ali follow..  21..................................................................................................................................................................................................................................................................................................................................................................................KSKHDILGRKKGAQVGAPTASRKRAHEQREQTLGVEYDRKNKISKIVDKRLGEKDGKSEEEKGAMRFTEERVKNYKRASKFNLTDDGDEEEEVLTHKGKALSDIEKYDKSMISDSDDDEEPGNLGSNMVKVAHFGGGEKTAEEHVREKISREDMISNLIAKTKLARHEKQQQKDELELMTESLDSK--YQALMGKMKASFRPTGRQPLEKDDYDKLTITLKTEADARATPADRKLSEEEEALKEKERLETLEAAPDADVDIDAGSKADARKVQAKNSRFEVKFDDEGGLIDEDTVEKSRILKKNLDGSDESDDDEDLEDEEEDLDDLLEDEDELEEDSDDEEAQEAQKVVKKAKKSAPEPAETLPFVFEMPKNYKKFCALLEKHSESMDLVLERLVKCHHPSLKEGNKKR.... 428
49 -14.100[A] KOG2412 Nuclear-export-signal (NES)-containing protein/polyadenylated-RNA export factor  ali follow..  10  2..................................................................................................................................................................................................................................................................................................................................................................................................................................................RFVFDEVFNSDTDSPEFEETCSTTSSTSSQCPTPEPSPAIKLPSFTKVGTKKLVNESVVILDPALENALRDLNLQSKLIPINEPIVAASSIIVPHSTNMPLPRA-SHSSLLDNAKNSNATAPLLEAIEESFQRKMQNLVLANQKEIQSIRENKRRVEEQRKRKEEEERKRKEAEEKAKREQELLRQKKDEEERKRKEAEAKLAQQKQEEERKKIEEQNEKERQLKKEHEAKLLQQKDKLGKAVTNFDKISKMFWHYKDKIAQIKQDIVLPIKKADVNVRNLLSRHKRKINPKFGQLTNSNQQLFKIQNELTQLINDTKGDSLAYHWILNFIAKAVVHQAETEVRVKPESA 350
50 -14.000[T] KOG2008 BTK-associated SH3-domain binding protein SAB  ali follow..  6..................................................................................................................................................................................................................................................................................................................................................................................................KLILNLYSNYKFFLLLLQIELENLNSATDEINKLEIELEEANSTFRILLNESTRRLKVSSKKLGNCIEKA-----RPYYEALDKAREAQIECQKAAVKFQRANEIHAAAKETVALAEQRFMSNSHEWQFD--NAWQEMLNHATQKVMDAETQKADCHAEHQRLTKL-------NAAEQKLQQLEDRFRRSINKSRPYFEEKQVCQDQLQTQKNRIQELQ-QQVAGAKSTYSTALRNLERISEDIHRQRGDFPTPPGPREPGVGAELNSPTSSALPSLPDFQLELEKCDYPSIAGSQMSLGAKTPQAAAETEDEEDACDYDETGAGELRGVVDERDLEALRQKILAVRPIEGGDGQQQNDVWEHELKATVDKLDHLMMLKETAKRQQTNRLKSTEQRPD 391
51 -13.900[D] COG4477 Negative regulator of septation ring formation  ali follow..  36.....................................................................................................................................................................................................................................................................................................................................................................................................ALEERKESLFDLPVQEEIDSVKKMHLVGQSQTIFREWNQKWLDLSSNSFADLEEHIFEAEQLNDSFHFFRARESVADSEAQIELMEGDVEGIRQGVAQLVEQEKRNSNKIQESLDLYDNLRSDIADNA-DLYGTVITELEKHLANIETEFSQFVTLNST-GDPIEAAEVLETAEEHTIALRAITEQIPSFIKTIE----------------------KDVPKRLEELQEASDKFVAEEYILPDNVNIKERMDDLHDHLVESSSLLEQFELDRVEAELGLIQEKVEELYAIFEREYSARRNVEKRSSVLKEYIEHIRANNKNLLLEIDHVTQALSGNEKGYVRGYQEHLESLDSDVDEILGNIQAKTMPYSILSRRVNSVVNALEDIEKNQIK... 405
52 -13.800[R] KOG2010 Double stranded RNA binding protein  ali follow..  11  2.......................................................................................................................................................................................................................................................................................................................................................................................................GTPASGRKRTPVKDRFSAEDEALSNIAREAEARLAAKRAARAEARDIRMRELERQQKELDEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELRESLSEVEEKYKKVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYREEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVS-HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELSQIRKLKLQLE--EERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVKTAAENAEKVEDELKAEKRKLQRELRTALDKIEEMEMTNSHLAKRLEKMKANRTA... 395
53 -13.300[Z] KOG1853 LIS1-interacting protein NUDE  ali follow..  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-ETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE--GYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA-----KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD---------------EARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGT-PLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSK. 296
54 -13.200[R] KOG1881 Anion exchanger adaptor protein Kanadaptin, contains FHA domain  ali follow..  379...................................................................................................................................................................................................................................................................................................................................................................................................DREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRK-AKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLV---------AKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRL----------KGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGP 755
55 -13.200[OUTIV] KOG3956 Alpha 2-macroglobulin receptor-associated protein  ali follow..  35..........................................................................................................................................................................................................................................................................................................................................................................................................................EANDPHFQQVKQEKYDPDFKSIQRPFRMAKLNLVWAKAQNRLTEPKLKSLYMELKIHDKEEIAWKQLNSQHKDKDGLKADELRRKLIGIMSSYDLLEHFDDTQDTEKLKPYKKFHDAEERHRNKSLFKDKKLNRLWEKAEISGFTAEELKSLKQEFDHHQDKVDVYYSLLENIGTVDTDKHENAINTEDLDTYNL-ISNDVNENDIKTHAQNVKSFENDLNTLRGHHTGIKDHYD------------RLERLVSSGPHSQDFIEPKVQGLWRVAQASNFTVKELESIKTELHHFESRLLKLRHLHAEHALQKEKYKGEKVKDKSSRFEEMEDQLKKQTRKVEKLQENIEKTIFKHTE................. 378
56 -13.100[S] COG5280 Phage-related minor tail protein  ali follow..  10  1................................................................................................................................................................................................................................................................................................................................................................................................MAKKISGITIAIGADTTGVTNGLKDIGKQSNSVNSELRDVERLLKLNPNNVELVAQKQQLLSKQVELT-----TKKLDGLKGAQADVDRQFKSGDIGEEQYRAFQREVVATEGRLDHYKQSLKDVESSSGENATKGLGGKFDELGQSVEDVGEAVKGGVLMEAADHLSVVGDKLKEDVDEGMDKITTTTGKASDEFKTQFDNIISSMAVDSFEDVGSALGTLSDVKTSIESAKSAIEAYGLSNKDFSTVLDSVTATSQ--RTGVAVDSLFDSAVKGAPQKDLGLNFSQGTELLGQFSKAGVDGDAALSSLSKASIIYAKGNKSLSEGLGETIEKIKNAKTKQEALTEAATKGASRMVDAIQRGAFNLSELGDVAKKSNGTISDTFNKTVDDIDEQQIASQ 436
57 -13.000[K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit  ali follow..  2.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SQRKLQQDIDKLLKKVKEGIEDFDDIYEKFQSTDPSNSSHRE-KLESDLKREIKKLQKHRDQIKTWLSKEDVKDKQ-SVLMTNRRLIENGMERFKSVEKLMKTKQF---------SKEALTNPDIIKDPKELKKRDQVLFIHDCLDELQKQLEQYEAQENEEQTERHEFHIANLENILKKLQNNEMDPEPVEEFQDDIKYVENNDDPDFIEYDTIYEDMGCEIQPSSSNNE 222
58 -13.000[S] KOG4791 Uncharacterized conserved protein  ali follow..  294.......................................................................................................................................................................................................................................................................................................................................................................................DSDPPLKRSLAQRLGKKVEAPETNTDETPKKAQVSKSLKERLADPNNEDATDKVNKVGEIHVKTLEEMLLERASQKHGESQTKLKTEGPSKTDDSTSGARSSSTIRIKTFSEVLAEEEHRQQEAERQKSKKDTTCIKLKTDSEIKKTVVLPPIVASKGQSEEPAGKTKSMQEVHMKTVEEIKLEKALRVQQSSESSTSSPSQHEATPGARLLLRITKRTWRKEEKKLQEGNEVDFLSRVRMEATEASVETTGVDITKIQVKRCEIMRETRMQKQQEREKSVLTPLQGDVASCNTQVAEKPVLTAVPGITWHLTKQLPTKSSQKVEVETSGIADSLLNVKWSAQTLEKRGEAKPTVNVKQSVVKVVSSPKLAPKRKAVEMHPAVTAAVKPLSSSSVLQEPPAKKAAVDAV 705
59 -13.000[UD] KOG2218 ER to golgi transport protein/RAD50-interacting protein 1  ali follow..  3....................................................................................................................................................................................................................................................................................................................................................................................................................................................SECVAGLSQTPQATLAANGAEDSRGGEMLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTD-----NGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSK--MQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFL---------------EQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWKILKDKLTSDFEEILAQLHWPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPAS. 328
60 -12.800[Z] KOG1003 Actin filament-coating protein tropomyosin  ali follow..  13  2.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVESESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEEDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE---------------EKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELE------------RSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKL----EKTIDDLEETLASAKEENVEIHQTLDQTLLELNN................. 283
61 -12.700[S] COG1340 Uncharacterized archaeal coiled-coil protein  ali follow..  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MTDLLQEFEEKRDILRKAIEEHIKKRDEAAQQ-SRNYAEQRDQLNAKAHEMRDQVKQKISQKNALIEEQKIRTEKEEHFQKLSELRKEYKKITEEANYASVNQRDIKA------------KERELQKLIKKQETMQLPKAEEDKVVQEIKRLSNEIKKMKEDREKQLSENEKVKALLAEDKEKTLARDLKKRAEEISNQISEISNDINKSLQELDEVRKKADEMHEMAIKYGKESEQEHEAFIQAKNDLKDVIAGLRTKKRATKKKEKDDELQQKAEVLFEKFKNGEELTTDDLLILQKA 292
62 -12.600[R] KOG4678 FOG: Calponin homology domain  ali follow..  14  305................................................................................................................................................................................................................................................................................................................................................................................STAEELQATLQELSD-QQQMVQELTAENEKLVDEKTILETSFHQHRERAEQLSQENEKLMNLLQERVKNEEPTQEGKIIELEQKCTGILEQGRFEREKLLNIQQQLTCSLRKVEEENQGALEMIKRLKEENEKLNEFLELERHNNNMKTLEECRVTLEGLKMENGSLKSHLQGEKQKATEASAVEQTAE-SCEVQEMLKVARAEKDLLELSCNELRQELLKANGE------KHVSSLLAKVEKDYSYLKEICDHQAEQLSRQEKASESDAEIKDMKETIFELEDQVE--QHRAVKLHNNQLISELESSVIKLEEQKSDLERQLKTLTKQMKEETEEWRRFQADLQTAVVVANDIKCEAQQELRTVKRKLLEEEEKNARLQKELGDVQGHGRVVTSRAAPPPVDEEPESSEVDAAG. 718
63 -12.600[S] COG4717 Uncharacterized conserved protein  ali follow..  386..................................................................................................................................................................................................................................................................................................................................................................................................VQARDRKRQLDETFELARQELEDAEKAVRAASSAILENSQRKDKEAALRAYDETQGQHQEQAKLREQLTFFERQQAKQKKTVIAAGMLFIVLFSLLQQWIPAISFGAALIVYWLVSGKSSSRNSRETRQPMTDISPAEAEMLREALWEDDRNKQHLLTQRAALQQKEAAERVIQQFEQWEAEMAPSFTQVERFMNELGFKEDPSFLLDAYSLMKDVKKEVKKKHELTIEAGRLKKHRRTFEERSDALHTLRKNIEREKEIEKQKKEIETDIHYTKEQQEIQYFHAQIEQLFAAAAAKDRDAFFAIAAISRQLKDTENKLHHVNAQLQGGYPEELELADSNT--LSELKDKQFVENERKERLTEEIEQLRSQIALLSVKQEQLEASGMVSDLKLQTEMQ 802
64 -12.600[K] COG5164 Transcription elongation factor  ali follow..  2..................................................................................................................................................................................................................................................................................................................................................................................................................................SDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRFLDIEAEVSDDE------------DEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSSSKQYRAAAQDGYVPQRFLLPSVDTATIWGVRCRPGKEKELIRKLLKKKFNLDRAMGKKKLKILSI.............................. 325
65 -12.600[R] KOG2220 Predicted signal transduction protein  ali follow..  264......................................................................................................................................................................................................................................................................................................................................................LVCRAAKKIGEEIARLRNAIDLFKAAQTRSGNETYLDEYFSRAKRNLTESTKDNEFIYNEIIPELSTLTSPGKAQLAKPLPIAVPLAENHRALTASDMRRNEIVNVEIMKLREATQTLNAVLASLNLPAAVETADGNSGLPPSLKEKANEVRQKGGIENVQTMLKDLPELLNR-----NREILDETERLLDEERDSDNQLRAQFKDRWTRISSDKLTEMFRTNAKKYREVITNAIEADKVVRQKFEANQKDQIQQSLPSASGSVDPNCSSVQRLKKLMDDVETIKAEREAIESELKGATFNMKDEFLI--LQKDGAIDEPALSLARIGQVLNPLQQQVRESVERQQSLVSEIQSAHGAFVSETGSCGSSRDTLYQELATAFDSYIELSGNLQEGTKDLTQLLVVFQNKISDFVFARKTEKEELLKDLTTESSRQACPATPAL 724
66 -12.600[S] KOG3990 Uncharacterized conserved protein  ali follow..  133..........................................................................................................................................................................................................................................................................................................................................................................................................................................AYKRALLKAQQEGRIPMSKKRPHEKTSSSHRDSAAAKKPSRNELGKSGSGANNSGVNAVSGAGLDLPDKISRGNGGNGTIAAPAAITVDTNSSDHVVAITYLKERIASLEKRLNQKDKE-------------LLEKDKQLTELKGKNFEKENDMRNRLKEVERLHDMKVDNLNRKIASVLKELAVLKKSSNKKTAAISKAEKEIIKRENLSPKEEILAT------------TGPEKPTKASSEPADLDKDEKSRDRDEERSEQGDRASVRSRSASSSPTPSSN........................................................................... 390
67 -12.500[S] KOG4421 Uncharacterized conserved protein  ali follow..  25...................................................................................................................................................................................................................................................................................................................................................................................SKLRAQATVLKKAVLESLREQLQQYATSLRRTEQEVDSLGFRNKQLESRVSQLQQEISVHEQPKKKDKDSGGRRGVQSNSRPDADPSLDAAQEALIFEELQKKIMENAQLTSLIDDKQRDLLLHTERIASLEQKLEKRIGDQNELE-KRLRKEVETLQHRNSELETKLVDAASMLGSEDALSATGSDTTPLHNLQQQSNSNQLTSEDRIALLEKEAAHWRAQFEVAKLHQAFVSSKDLSTCSCSTAAAGVTVRPAESEAKGSQRARDSLQDPPEPPTKEQLIYSVFSK---------KFEDLMRLKVQAESKLRSYELEVQHLQNCLENATHELKAKDDQLASLGGALQMLEEELTTTRINYEEQISVLTEQVISLSDQLAACK............................. 406
68 -12.500[KTDL] KOG2043 Signaling protein SWIFT and related BRCT domain proteins  ali follow..  108................................................................................................................................................................................................................................................................QVSSEDRSALWALVTFYG-------GDCQLTLNKKCTHL------------VPEPKGEKYECALKRASIKIVTPD----------WV-VSEKTKKDEAFYHPRLIIYEEEEEEEEEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKENLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQRPSNVAHILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEEG........... 604
69 -12.400[S] KOG4356 Uncharacterized conserved protein  ali follow..  529.................................................................................................................................................................................................................................................................................................................................................................................................................................................DATELKEYPVHGQYHVKSKGKVNAKKDNAPLDVKFERNQEGHALKVTIRPGTKEEEEDKENQDQEPESDQQQQQQVQNKKPGKKQRKKNKKERSLSESACADMILQEPLAKTNELQPRATFKLPPQRKQRSYSECNDSTGRSHRGILKRFSRYGPRPSMSDSWSSIDDSSSYSCSVDA------SGTSLFSQSFGGIPEEDRSDAGLSESCKKTVRFNDHIMKQVFRLDSSILGQR-----------KKNQKRRDLKLRAQQRRLSEGDSVDYEETRGSALKQEENPSRNCNDSGLDLTGAAGAHSNNNESDAKNTMMFEMDD............................ 834
70 -12.400[S] KOG4687 Uncharacterized coiled-coil protein  ali follow..  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................MDLDDVASHHGFGQHMATYNVETSAVHRKLQSKVEALRILRQELEQFRVERDQYKLVAETLQLRYSALKSNSELLAVGGCGSENSSLAALLHETREQNLKLSTEVEALRQRLNELHGDELLRETEASNKSRVQAMASENAARNKEELQWRRERANFICHLEGLKKRNAQLA-FDLKAVIDEKEELITERDAYKCKAHRLNHELFVALRAKKTHPRLLDIDGVLENKYLHERVKIQDSELELTKQSINKYKTMLDAKRKKGIVKLGGGSTNEDTILSPRQVKTPQKTESLSDLKSLCLALLDNLNDKNLALTHQKKTNKILAGKMTELEQRWQQLLSGNDDNAEEQEEDV. 360
71 -12.100[R] COG4867 Uncharacterized protein with a von Willebrand factor type A (vWA) domain  ali follow..  12  1.............................................................................................................................................................................................................................................................................................................MAKSDGDDPL-----------RPASPRLRSSRRHSLRYSAY----------------------PDPLAPPVDLRDALEQIGQDVMASPRRALSELLRRGTRNLTGADRLAAEVNRRRRELLRRNNLDGTLQEIKKLLDEAVLAERKELARALDDDARFAELQLDALPVSPAKAVQELAEYRWRSGQAREKYEQIKDLLG--RELLDQRFAGMKQALAGATDDDRRRVTEMLDDLNDLLDKHARGEDTQRDDEFMTKHGEFFPENPRNVEELLDSLAKRAAAAQRFRNSLS---------------QEQRDELDALAQQAFGSPALMRALDRLDAHLQAARPGEDWTGSQQFSGDNPFGMGEGTQALADIAELEQLAEQLSQSYPGASMDDVDLDALARQLGDQAAVDARTLAELERALVN............................................................... 376
72 -12.000[A] KOG2991 Splicing regulator  ali follow..  2........................................................................................................................................................................................................................................................................................................................................................................................................................................TNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATK---------------EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQIAQLEAELALQKKYSEELKSSQDELND------------FIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAG. 335
73 -12.000[R] KOG4331 Polytopic membrane protein Prominin  ali follow..  166...................................................................................................................................................................................................................................................................................................................................VAFTLLMTSQYAQIGLDK-LPNRMNQCVDDLQSYKRDSLLIDDYQVLNSTITKQLSTAGYNVVDRVKKLTAHVIDVFMNISKVAQEMHDGLESVHGKVRFLNEEGSRFEAEFSRLRNTANEELVKCLENELEPVRSMCAKAERLLESLAVTQFKIDQKFLPDATETGLSEIVNANITQVLAASNNQFEQLESRIQHEIDKETYSAQNMLKQIGDDLFLVAETISTQLRKVTFEALYSTVSYVSDPKKTPTLKYMQYSWYA--FSNLVCQPMRNPLSHPESLSLADRYINLWKANHTPENDIEVTLQSKSPAEIIRACSRNEDKKYHLNKLQDFEKDAYNQLQISLRTRDLEKLASVNVSKVSQQGLNAIKHAMDELDLASKTREFEESLDANSGRPKAVTLVLEQIRELEIQFAKPLRSRLEALYSNITSLDEKLSQLQVPVSSLLVKLQHAQALLAENMR 730
74 -11.900[U] KOG1162 Predicted small molecule transporter  ali follow..  6............................................................................................................................................................................................................................................................................................................................................KELEAQIPEWKEAFVNYCLLKKQI------------KKIKTSRKPKPASHYPIGHHSDFGRSLFDPVRKLARTFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKVNQFHKPKETEFLERGEILKKQLETLAELKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGELSEIQSETSRTDEIIEALERNGVSFINSATRSLRVDIPDAVAGAEGGIARSIATAMSVLWEELVNNPRSDFTNWKNIQSAEKKIRSAFVELYRGLGLLKTYSSLFTKIMKKFDKVAGQNASSTYLKVVKRSQ---ISSDKVVRLMDEVESIFTKHFANNDRKKAMKFLKPHQTKDSHMVT........................................................................ 386
75 -11.900[K] KOG2150 CCR4-NOT transcriptional regulation complex, NOT5 subunit  ali follow..  12  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................MAHRKLQQEVDRVFKKINEGLEIFNSYYERHESCTNNPSQKDKLESDLKREVKKLQRLREQIKSWQSSPDIKDKDSLLDYRRSVEIAMEKYKAVEKASKQERERRDISEYLSQMIDELERQYDSLQVEIDKLLLL------------NKKKKTSSTTNDEKKEQYKRFQARYRWHQQQMELALRLLANEELDPQDVKNVQDDINYFVESNQDPDFVEDETIYDGLNLQSNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAV 338

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.