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Query: [S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLRYASNAYHIGRYAQRLFATGQRNRVFHQYIASTSLQTTSLRYASTDRSKVEYTLKMLREDVQKQDEEAQKVLSLMKSDKDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTVSDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKFLQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNLSMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACRARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLYLPEEVSFPDRLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKRLRHKLNSMIEDVDSMVDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAKLKESKGEQADDGEQRERIEALLKTIDEDSDGIVDKQLVLEVIELLEKHTDVHVSAAQMASMIGTLKKEDEVAGLTEEIRKVQSGNYQMPILPTGPSSADAFNQPQGVYTASKQVPARSEQEGVEQKQQVENGPVGIPDVDTKVTSTLQQNSSKTSSSSTTKSTSDSKSALast
1 -168.000[S] KOG1043 Ca2+-binding transmembrane protein LETM1/MRS7  ali  100  1MSLRYASNAYHIGRYAQRLFATGQRNRVFHQYIASTSLQTTSLRYASTDRSKVEYTLKMLREDVQKQDEEAQKVLSLMKSDKDVATVKPPLKDRIIHELKHYYHGFRLLALETRVSAKYLWTVLRGATLSRRERQQLVRTVSDLFRLVPFSFFIIVPFMELALPIFIKLFPGMLPSTFQESSKEEEKWRKQVKLRVEMAKFLQDTIEEIGLERKTRNKESTRSLEFALFIKKVRNEGGYVSNEELLKFSKLFEDEITLDNLSMGQLRSLCRLMSINSLGSPEILRFQLNMKIRELKADDKQIAAEGGVDALSSIDLQSACRARGMRAIGVSEERLKEQLVQWLELSLNDKVPPALLLLSRTLYLPEEVSFPDRLKAIVQNLPDGLAETTKQKLTEMEGGQIDHKARIELIRSIESAIANEKKDEEKKKKAAEEALKSKEEAEKAKVQEKEKLVDVAAQAIVHELKKDIYDAVASTSSTTEAKEPAAKPSEAKEEKKEDITVDKKDLSHIEEIIVGGPIKEAKHDILGLREKVLEHKEDLMEINSLDGAFAETKIAKRLRHKLNSMIEDVDSMVDKLEDEKRNIREMLIDPTVENSVDLKKEREVRIQDVIDSLAKLKESKGEQADDGEQRERIEALLKTIDEDSDGIVDKQLVLEVIELLEKHTDVHVSAAQMASMIGTLKKEDEVAGLTEEIRKVQSGNYQMPILPTGPSSADAFNQPQGVYTASKQVPARSEQEGVEQKQQVENGPVGIPDVDTKVTSTLQQNSSKTSSSSTTKSTSDSKSA 784
2 -81.100[T] KOG4263 Putative receptor CCR1  ali follow..  16  104..............................................PEDEKRKELDTVKSKRDQMRDNMQDYIFTRYFNYVKNYDKVLEKNFPKAMQLYRVFFDGVKDFFGDMKRFLKIARIAQGIRALNRQELELYMQMPRDMMKVAPALIGCSLPMVGYAFFPLVFYYPSFLTAHFWTPQQRSEFQSYYMKRRLCNNKDVFRCLQDKLKATA----SHPKHSAFADILGQLG-SGTHPTPEMLIDVKDIFAEGYSLLGMSRKHVRNLVNLHGL---PSSIFKRHRLHEHAFLVHYMDQAITREGGVHNLTPDALRYSCYLRGLNPDSLSSEAMIEWLRKWVKVSTSIQGEHITLFLHLPILLGYNHPNNWKTIY........................................................................................................................................................................................................................................................................................................................................................................................................................ 431
3 -10.700[ZD] KOG0028 Ca2+-binding protein (centrin/caltractin), EF-Hand superfamily protein  ali follow..  14  76................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EAQKCDIKEAFDLFDNEGTGYIEVKELKVAIREIKRMISDIDKDLQLMTIKMAEKDTKEEILKAFRLFDDDDTGKISFRNLKRVARELGETLTD--------EELREMIDEADLDNDGEVNQEEFLRIMK.............................................................................................................................. 216
4 -10.600[S] KOG4360 Uncharacterized coiled coil protein  ali follow..  3................................................................................................................................................................................................................................................................................................................................................................................QSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHILSEQNEEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIV---DLQH--KLKEHVIEKEELKLHLQASKDAQRQLTMEELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPI. 427
5 -10.400[T] KOG0027 Calmodulin and related proteins (EF-Hand superfamily)  ali follow..  10...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RQLETKKPQTGRKISTSSRGTIHSQQSQPEDIQMKYTRKELKEYRQLFNMFDTDGSGAIGNEELKQAMIEIDNVIKEVDAACMKKSQNIVKSTNEELIRECFEIFDQDRNGIITENEFKYIAKEFGDFDDEL---------AEKVFRELDVSANGHLSADQFATIVEDYLLND----PKHDIDTGDSDVERYD.................................................................................................... 210
6 -10.200[R] KOG4403 Cell surface glycoprotein STIM, contains SAM domain  ali follow..  13  61..................................................................................................................................................................................................................................................................EKLSFEAVRNIHKLMDVDVEESDEFLREDLNVKHSTFHGEDKLI---------SVEDLWKA---KSSEVYNWTVDEVVQWLITYVEL-RKLQLSGHAMMTGTVLKMTDRSHRQKLQLKALDTVLFGPPLLTRHNHLKAYIQNRYSKEHMKKMMKDLEGLHRAEQSLHDLQERLHKAQEEHRTVEVEKVH-----LEKKLRDEINLAKQEAQRLKELREGTENERSRQKYAEEELEQVREALRKAEKELESHSSWYAPEALQKWLQLTHEVEVQYYNIKKQNAEKQLLVAKEGAEKIKKKRNTLFGTFHVAHSSSLDDVDHKILTAKQALSEVTA------------ALRERLHRWQQIEILCGFQIVNNPGIHSLVAALNI................................................................................................................................................. 456
7 -9.470[S] COG1511 Predicted membrane protein  ali follow..  10  2...............................................................................................................................NTIRSQWKDIVT---SKKLLIPIIAILFVPL----------IYSGVFLKAYWDPYGTVDQLPVVVVNQDKGATYEGEKLQIGDDLVKELKDNNNFDWHFSNDLDQSLKDLLNQKYYLVVEIPEDFSKNASTVLDKNPKKLDL----KYHTNAGSNYVGATIGEKIDKLKASKGLSDASSGAKKIDTKDAKNGSAKENLAKLKESTATISDKTAQ-LADGAAQVTSGIQSLDSSLGKFQDSSNQIYDKSSQLAAGSGELTSKMNELLAGLQNVQKGTPNLTNGLDQLNSKV-QEGSEKAAKAEKIINALDLTKLETAVNNLEKSETAMKEFKKQLTDFENSLKNRDQAFKNVINSSDFLTAEQKSQLINSVEKKLPQVDAPDFDQILSQLPTADQLPDIATIKSSLEDVKAQVAQVKAMPEATSKYNGAKTIQDAIDRLADKIYNGSQKLTDGQTKLTAGIGEYNKQFAKAKAGSEQLVSSQVSGGLFKLLDGSKQVQSGSSKLDGSASLDTGLGKLLDGTGELSSKLK-ADQTGDIDADDQTYGMFADPVKTKDDA..................................................................................................... 572
8 -9.150[S] KOG1103 Predicted coiled-coil protein  ali follow..  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................PNLLDDSFDPTFQSTSKKLVLPSIRKVQPEYDNLPEEQGVNDFSSDELMKLLSFMEGEVQAREDVIDHLKRERTKILLSEAKYGKLNMNDPFAALRRDSAITGEQIDEEKIVQMYESQVDQLDKMMAVQKQSQRNAAVLLV--------ALEKKQYKLVKKLEADREAKIRYAKQGDDLVAHLEK-NQLQQQIEFHIEEKRKAEI-----AKDKMEMTLGNEKKRHESIVLYLIQERKQMLLKMHELRVKAEQIMLQNQNDPTKPGPSSALSERELIEELKKEVTFLRAERESLTKTQKMVKTENLSLRETVRGQEADLQMLRRNLTLTGAKMSIDK 326
9 -8.900[R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains  ali follow..  432...................................................................................................................................................................................QRDEFEDMLRALTLERSQIREAMGFALD-----------NAEAAGEVVEVLTESLTLKETSIPTKVARL--LVSD--IIHN-SSARVKNASAY------------RTKFEATLPDIMESFNDLYHS---GRITAEALRVIPESKFCSHSYFVQERVLKVLQVWADWFL---------------------------------FSDAYINGLRATFLRSRNFGVTSFHSICGDAPDIEKKGLIGNMNDADKINQDAALAMGEGAARQELMNRPISELERRCRHNGLSLLGGREMMVARLVCLKDAEKQRGYEVVDENAKYRQGHSTWEEVNIEPKRMKTSYDKVETEEPVDLASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDV-------------------EQRQKLRHI----------EIALIEYRESLEEQGMKNSEEIE-RKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDDHDRSRERDRDWRRRGM 956
10 -8.620[YU] KOG4460 Nuclear pore complex, Nup88/rNup84 component  ali follow..  407.............................................................................................................................................................................................................................................................................................................CTHEAGVHSVGLTWIHK--------------------LHKFLGSDEEDKDSLQELSTEQKCFVEHILCTRPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIWPLLSTVHPASPPLLCTREDVEVAESSLRVLAETPDSFEKHIRSILQRSVANPAFLKASEKDIAPPPEECLQLLSRATQVFREQYILKQDLAKEEIQRRVKLLCD-----QKKKQLEDLSYCREERKSLREMAERLADKYEEAKEKQ--EDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIPD------------QLRHLGNAIKQVTMKKDYQQQKMEKAYQRKCIQSILKEEGE---HIREMVKQINDIRNHVNF...................................................................................................................... 741

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.