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Query: [K] KOG0775 Transcription factor SIX and related HOX domain proteins, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGHARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGSLast
1 -116.000[K] KOG0775 Transcription factor SIX and related HOX domain proteins  ali  100  1MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRTIWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGHARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS 284
2 -37.800[K] KOG0774 Transcription factor PBX and related HOX domain proteins  ali follow..  15  144.................................DNSIEHSDYRAKLTQIR---QIYHTELEKYEQACNHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSSGSFNLPNSGDMFMNMQSLNGDSYQGSQVGANVQS......................... 373
3 -29.700[K] KOG0773 Transcription factor MEIS1 and related HOX domain proteins  ali follow..  22  325............................................................................................HELKQGYKEKIVDIREEILRK------------RRAGKLPGDTTSVLKAWHSKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSNPSSSTVLKNKRKSNAGDNSGRE............................................................................... 428
4 -22.500[K] KOG2252 CCAAT displacement protein and related homeoproteins  ali follow..  11  313................LCKRIAFELKNHSIPQAIF----------------AERILCRSQGTLSDLLRNPKPWNKLKSGRETFRRMYNWVAQPLATRLAILDMKTEDVNRASGMSPPTPA--VSKRPRLVFTDIQKRTLQAIFKETQRPSREMQQTIAEHLRLDLSTVANFFMNARRRSRLGGNIDEPTPFQQVKNISPPPVGDTSDALLNGDD...................................................................... 508
5 -20.500[K] KOG1168 Transcription factor ACJ6/BRN-3, contains POU and HOX domains  ali follow..  19  221..................RELEAFAERFKQRRIKLGV--------QADVGKALANLKLPGVGALSQSTIFESLTLSHNNMIALKPI--QAWLEEAEAQAKNKRRDPDAPSVLPAG-------EKKRKRTSIAAPEKRSLEAYFAVQPRPSGEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRIVSSVTPSMTGHGSAG....................................................................................... 386
6 -19.500[R] KOG0492 Transcription factor MSH, contains HOX domain  ali follow..  23  143............................................................................................................................RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRSAKAKRLQEAELEKLKMAAK......................................................................................... 213
7 -18.900[K] KOG2251 Homeobox transcription factor  ali follow..  19  47............................................................................................................................RRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGG 206
8 -18.800[K] KOG0483 Transcription factor HEX, contains HOX and HALZ domains  ali follow..  25  71.............................................................................................................................EKKRRLGVEQVKALEKNFEIDNKLEPERKVKLAQELGLQPRQVAIWFQNRRARWKTKQLERDYG............................................................................................... 134
9 -18.800[K] KOG0485 Transcription factor NKX-5.1/HMX1, contains HOX domain  ali follow..  24  120............................................................................................................................KRPRTAFSAAQIKALETEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTSDVET............................................................................................... 184
10 -18.800[R] KOG0488 Transcription factor BarH and related HOX domain proteins  ali follow..  22  167............................................................................................................................KKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSS........................................................... 267
11 -18.800[K] KOG0850 Transcription factor DLX and related proteins with LIM Zn-binding and HOX domains  ali follow..  18  130............................................................................................................................RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFK----KLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGA 285
12 -18.400[K] KOG0842 Transcription factor tinman/NKX2-3, contains HOX domain  ali follow..  26  129............................................................................................................................RKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSPR....................................................................................... 201
13 -18.100[R] KOG0489 Transcription factor zerknullt and related HOX domain proteins  ali follow..  20  318..........................................................................................................................KSRRRRTAFTSEQLLELEREFHAKKYLSLTERSQIATSLKLSEVQVKIWFQNRRAKWKRVKAGLTSHGLGRNGTTSGTKIVVP............................................................................... 400
14 -17.500[K] KOG0847 Transcription factor, contains HOX domain  ali follow..  22  168..........................................................................................................................QKKQSRPTFTGHQIYQLERKFEQTKYLAGADRAQLAQELNMSESQVKVWFQNRRTKWRKKEAADNALVKRGASGDKSPCSLSP............................................................................... 250
15 -17.300[K] KOG0484 Transcription factor PHOX2/ARIX, contains HOX domain  ali follow..  16  91............................................................................................................................RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGA... 247
16 -17.200[K] KOG0848 Transcription factor Caudal, contains HOX domain  ali follow..  23  185..........................................................................................................................TKDKYRVVYTDHQRLELKEFHY-SRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVLGPT........................................... 303
17 -17.000[K] KOG0486 Transcription factor PTX1, contains HOX domain  ali follow..  31  93............................................................................................................................RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR...................................................................................................... 150
18 -17.000[K] KOG0843 Transcription factor EMX1 and related HOX domain proteins  ali follow..  18  321..........................................................................................................................QQKRVRTMFNLEQLEELEKVFAKQHNLVGKKRAQLAARLKLTENQVRVWFQNRRVKYQKQQKLRAAVTSAEAASLDEPSSSSIASIQSDDAESGVDG................................................................. 417
19 -16.600[K] KOG0487 Transcription factor Abd-B, contains HOX domain  ali follow..  19  184..........................................................................................................................SSRKKRCPYTKQTLELEKEFLF-NMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE............................................................................................... 250
20 -16.300[R] KOG0494 Transcription factor CHX10 and related HOX domain proteins  ali follow..  24  137............................................................................................................................RRHRTIFTQYQIDELEKAFQDSHYPDIYAREVLAGKTELQEDRIQVWFQNRRAKWRKT...................................................................................................... 194
21 -15.700[K] KOG0844 Transcription factor EVX1, contains HOX domain  ali follow..  24  182..........................................................................................................................QMRRYRTAFTREQIARLKEFYREN-YVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGG........................................................................... 268
22 -15.400[K] KOG3802 Transcription factor OCT-1, contains POU and HOX domains  ali follow..  23  186.....................EETPTSDELEQFAKQFKQRRIKLTQADVGLALGTLYGNVFSQTTICRF-EALQLSFKNMCKLKPLWLE----EADSSTGSPTSIDKIAAQGRK----------RKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKR....................................................................................................... 335
23 -12.300[R] KOG0493 Transcription factor Engrailed, contains HOX domain  ali follow..  17  453..........................................................................................................................DEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP.............................................................. 552
24 -11.200[R] KOG0490 Transcription factor, contains HOX domain  ali follow..  12  58...........RRFGTKCQGISPSDLVRKARSKVFHLN-NKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDALQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR-MKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQGDYYAPGSNYDFFAHGPPSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHAADNP 339
25 -10.100[K] COG5576 Homeodomain-containing transcription factor  ali follow..  15  168.............................................................................................................................SKKQRLTADQLAYLLREFSKDTNPPPAIREKIGRELNIPERSVTIWFQNRRAKSKLISRRQEEERQ............................................................................................. 233
26 -9.300[K] KOG4577 Transcription factor LIM3, contains LIM and HOX domains  ali follow..  13  58...............ADCQQLADR-DFFKRFGTKCT---QQGIPPTQVVRKAQDFV-YHLHCF--ACIICNR-QLATGDEFYLME----------------------KEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSI 317
27 -9.020[S] COG5484 Uncharacterized conserved protein  ali follow..  13  1..................................................................................................................................MVDKHIQAYKD------YAKGMKYKDLAEKYGVSVNTIKSW----KQRHGWQRKKGAPLKKGVHTKKVGAPLGNKNALGNNGGAPKGNQNA............................................................... 81

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A. XtalPred: a web server for prediction of protein crystallizability. Bioinformatics. 2007 Dec 15;23(24):3403-5. Epub 2007 Oct 5.