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Query: [U] KOG0058 Peptide exporter, ABC superfamily, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKALast
1 -175.000[U] KOG0058 Peptide exporter, ABC superfamily  ali  100  1MRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRRLRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLNIRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGKYYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISGQMTSGNLIAFIIYEFVLGDCMESVGSVYSGLMQGVGAAEKVFEFIDRQPTMVHDGSLAPDHLEGRVDFENVTFTYRTRPHTQVLQNVSFSLSPGKVTALVGPSGSGKSSCVNILENFYPLEGGRVLLDGKPISAYDHKYLHRVISLVSQEPVLFARSITDNISYGLPTVPFEMVVEAAQKANAHGFIMELQDGYSTETGEKGAQLSGGQKQRVAMARALVRNPPVLILDEATSALDAESEYLIQQAIHGNLQKHTVLIIAHRLSTVEHAHLIVVLDKGRVVQQGTHQQLLAQGGLYAKLVQRQMLGLQPAADFTAGHNEPVANGSHKA 766
2 -109.000[V] COG1132 ABC-type multidrug transport system, ATPase and permease components  ali follow..  31  2..................................................................................................................................................................MNDKDLSTWQTFRRLWPTISPYKAGLIVAAIALILNAASDTFMLSLLKPLLDDGFGNSNSSILKWMPLAVIGLMVVRGVTGFVSSYCISWVSGKVVMHIRRRLFSHMMGMPVSFFDQQSTGTLLSRITYDSEQVAASSSSALVTVVREGASIIGLFIMMFYYSWQLSLILIVIAPIVSISIRLVSKRFRNISKNMQNTMGEVTTSAEQMLKGHKEVLIFGGQKVETERFDAVSNRMRQQGMKLVSASSISDPIIQLIASFALALVLYAASFPSVMETLTAGTITVVFSAMIALMRPLKSLTNVNTQFQRGMAACQTLFSILDMEQEK-DEGKLEVERAKGDIEFRHVTFYYPGK-DTPALNDINIHLEAGKTVALVGRSGSGKSTIANLLTRFYDVSEGSILLDGHDLRDYRLGALRNQVALVSQNVHLFNDTVANNIAYARNEYSRAEIEEAARMAYAMDFINKMEHGLDTVIGENGIMLSGGQRQRIAIARALLRNCPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVIEDGRIVERGVHAELLVQQGVYAQLNRMQFGQ...................... 582
3 -93.100[P] KOG0056 Heavy metal exporter HMT1, ABC superfamily  ali follow..  24  200.............................................................................................................................................PYNPHQRLDNDTANESQGNVQTGSAFRNGWRKLRTVFPYLWPKQIAVIVCIILLLAGRVIKLFLPIYRKKLVDSLTIAPIVFRWDFVLIYVALSFGSMGLFNNLRTFLWIRVQQYTTREIEIELFRHLHQLSLRWHLQRKTGEVLRVMDRGTDSINNLLNYIVFSIAPTILDLLVAVAYFVYANWWFGLIVFLTMFLYIASTIAITEWRTKYQRRMNLADNEQRARSVDSLLNFETVKYYGAEHYEVDCYREAILKYQKEEFLSMLTLNMLNTAQNIILCLGLLAGSLLCVYLVVHHTLTVGDFVLFSTYLMELYMPLNWFGTYYRAIQKNFVDMENMFDLLKEEEEIVDAPGCSPLLTAGGIEFSNVTFGY--SPEKIVLRNVSFTVPAGKTVAIVGPSGAGKSTIMRLLFRFYDVQTGAILIDGQNIKLVQQQSLRKAIGVVPQDTVLFNNTIFYNIEYAKLGASDEAVYEAARAADIHERILGFPEKYETKVGERGLRLSGGEKQRVAIARTLLKAPIIVLLDEATSALDTHTERNIQAALARVCANRTTIIVAHRLSTIIHADEILVLQQGSIAERGRHEELVREDGIYADMWQQQLKNLDAEQSGGSDNGDASAESGSEK 837
4 -92.000[V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain  ali follow..  24  134....................................................................................................................................................................QKGGRKPSMIASLWSRLQGAESALVYCIVAGFFLTIIGLVIPVFSQIFVDDILVQGRMLWLHPLLLAMAIAAILQGSLTLLRLRYLRRLKIRLAVGMSSRFLWHILRLPVSFYAQRFAGEISNRTTL-NDQVADVLAGQLATTIIDTLMVLFYALVMVQYDWVLTLMVVSFAAVNVLTLQWISRQRIDANQRLIQEYGKAAGISIATLQSIETLKASGLESDFFSRWSGYYTKALNSQQELGITNQTFSVLPTLLSALSAMLLLIVGGFRVMDGHLSIGMLIAFQGLMSGFQQPVNNLVNFGTTLQELEGNLIRLDDVLDNPVGTSSSSLQALPKLQGYVELKNITFGY-SRLEAPLIENFNLSIKPGQRVALVGGSGSGKSTIAKLVSGLYQPWTGEIYFDSQPREEISLQLLTNSVAMVEQEILLFGGTVRDNLTLWDTTVPDKNLMRACQDAAIADVIFSMSGGYDAELIEGAANLSGGQRQRLEIARALVNNPSILVMDEATSALDAETEKIIDQNLRRR--GCTCIIVAHRLSTIRDCDQIIVLERGKVVQQGTHQELWQVEGAYSRLIRTE......................... 711
5 -91.700[CO] COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components  ali follow..  20  1..........................................................................................................................................................................MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQ-QALKGISLQVNAGEHIAILGRTGCGKSTLLQQLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEILRRVGLEKLLE--DAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQG.......................... 572
6 -91.300[U] KOG0057 Mitochondrial Fe/S cluster exporter, ABC superfamily  ali follow..  26  57.............................................................................................................................................ITPMVNARVMFFSTSTSAPHPEKINRTSSENILRMISSYLWMKCFRVISAFACLVGAKFLNVQVPFLFKVAIDWLSSSSFVDSNPYLVAAFATPSSGSSAFNELRTSVFSKVALRTIRTISRKVLSRLHDLDLRYHLNRDTGALNRIIDRGSRAINTILSAMVFNIMPTILEISMVSCILAYKGAVYALITCLSVGSYIAFTLAMTQWRIKIRKAMNEAENDASTRAIDSLINYETVKYFNNEDYEARKYDQLHENYEDAALQSRKSFALLNFGQSFIFSTALSTAMVLCSQGIMNGQMTVGDLVMVNGLLFQLSLPLYFLGVVYSDTVQGLVDMKSMFKFLEERSDIGDKDIDRKLPPGGSISFENVHFSY--LPERKILDGISFEVPAGKSVAIVGSSGSGKSTILRMIFRFFDVDSGNVKIDGQDIKEVRLESLRSSIGVVPQDTVLFNDTIFHNIHYGNLSATEEEVYNAARRAAIHDTIMKFPDKYSTAVGERGLMLSGGEKQRVALARAFLKSPAILLCDEATSALDSKTEAEIMKTLRSLASNRTCIFIAHRLTTAMQCDEILVMEKGKVVEKGTHEVLLGKSGRYAKLWTQQNSKLE.................... 679
7 -89.300[O] COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components  ali follow..  26  3..............................................................................................................................................................APKTVSAESGETLKTLRNLWPYMWPSRMRVVWATFYLVLSKIVLILVPYFFKWVTNALNGQLHAPYYIPVVLVGAVMLVLQAGLNQLRDALFASVGQYAVRQLAYKTFVHMHELSLRFHLERRTGGLSRVIERGTKGIETIVRFTILNTLPTILEFALTAVIFAFAGLSYLVVVAATVWLYTWFTIRASDWRINIRREMNDSDTDANTKAIDSLLNFETVKYFGNEAMEAKRFDGAMARYEKAATQTWTSLGWLNFGQAVIFGAGMAIVMVMSAMEVQKGTQSLGDFVFINALLMQLSIPLNFIGFIYREIRQGLTDIEQMFDLLDVKQEVKDKPGAPALKVDGAISFKDVHFAY--DPQRPILRGISFDVPAGKTVAIVGPSGAGKSTISRLLFRFYDIQSGSITIDGQDVRDVTQESLRKFIGMVPQDTVLFNDTIAYNIRYGRTDASEEDVEKAAELAQIAGFIKHLPDGYKSMVGERGLKLSGGEKQRVAIARTILKAPPILILDEATSALDTATEQEIQSALDIVSRGRTTLVIAHRLSTVIGADEIIVLKDGLIAERGTHRHLLDQKGLYASMWDRQREASEAEERLRQVRESDDMGVVLRG 623
8 -71.800[CO] COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components  ali follow..  20  2.....................................................................................................................................................................DKKKQRSLNLWLKQQSKLAKRWLAIAVGLGVLSSLFLVAQAALLASILHQLIIEQDKHLLIPHFFGLAALIAVRALCSWGREIAGFRCGEEIRRYIRQLILDKLRDLGPAYIKGKPAGSWAALMLEQVENMHDFFARYLPQMSLSVLVPFVILAVVFPVNWAAGLIFLLTAPLVPLFMALVGIKAADASRKNFKALQRLSGHFYDRLQALTTIRLFDRTTAETEHMRGASEVFRHRTMDVLRIAFLSSAVLEFFTSISILTAVYFGFSYIYGASVTLFAGLFVLILAPEFYQPLRDLGTYYHAKQLAVGAAESIVDFLQTEVDTLHSGERHLSDNDDEIIANDLVVLSPQ--GKRLAGPLSFTLQSGKTTALVGPSGAGKTSLINTILGFM-PYQGSLTINGIELRELDHAQWRQTISWVGQNPLLLYGTIRDNVTLGKHNIADEQVTQTLQAAYAQEFVE--QQGLDYPISDRSAGLSVGQAQRLALARAILQNGRFWLLDEPTASLDARSEQYVMRGLTESIQQRTALFVTHQLQPLQSVEQILVMENGLLVQAGHFEDLSQQSGLFATMLAAN......................... 582
9 -69.800[R] COG4618 ABC-type protease/lipase transport system, ATPase and permease components  ali follow..  19  15................................................................................................................................................................................TAAVVSPLKSTFLGVALVSGVVNILALTSPLFMLQVYDRVLASGSLPTLVGLALLALGLYGFQCLLDIIRARVLIRIGEDFDMRYSGRVHDAVVRLPLV---NRMPGDGLQPL-RDLDNVRGFLSGTGPTAFFDLPWMPLYLGLCFLFHVWIGVTALAGAVLLVSLTILTNIFSQKPIRDTMVENMARNRQLEASRRNAEVVQAMGLGRRLGKRWQSSNEAYLAANRKAGDVAGGLGNLAKSLRVVLQSAILAVGAWLVIRQEASGGVMIASSIMMGRALAPVDLAISNWKSFVAARQSWARLRELFAQMPA--NAAAMALPKPEKELRVENVTIVPPGE-RKPTVTGLGFVVTAGNALGIIGPSGSGKSTLARILTGAWMPAAGKVRLDGASFDQWDRETLGRHIGYLPQGVELFDGTIGENISRFDDNPDPEAIIAAARAAGAHELILRFEKGYDSDIGEAGSTLSAGQRQRIGLARALYGDPFIVVLDEPNANLDAEGEAAVVKAITSVARGGIAVVVAHRPSAIGAVDYILMMEDGRMKAFGPRDEVLSKVLRVPQAQAAKGFAASAQTVSPLRVVANVQPKPALV 598
10 -67.700[QP] COG4615 ABC-type siderophore export system, fused ATPase and permease components  ali follow..  16  1.............................................................................................................................................................................MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRL-----IETADTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQLGSASLLAGLTSDVRNITIAF-VRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAITIWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVNLYIPDAQEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWM---ANSLGWADTNVAATYSLTLLFLRTPLLSAVGALPTLLTAQVAFNKLNKFALAPFK-AEFPRPQAFPNWQTLELRNVTFAYQD--NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQPEDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWL-----AQLKMAHKLELSNGRIV-----NLKLSKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQGKTIFAISHDDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVART............................. 546
11 -44.800[R] COG4619 ABC-type uncharacterized transport system, ATPase component  ali follow..  27  8.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LQLQNVGYLA---GDAKILNNINFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLIFPWQIRNRQPDPAIFLDF-----RFALPDSI---LTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEMIHRYVRNIAVLWVTHDKDEINHADKVITLQPHAGEMQEARYELA...................................... 225
12 -41.400[I] KOG0064 Peroxisomal long-chain acyl-CoA transporter, ABC superfamily  ali follow..  16  81.............................................................................................................................................AEAEKLLVAQQLKKKATNNLVEPGLNKEFLKHLQMLAKIMIPETGLLSVHTFCLISRTFLSIYVAALEGALVKFIV-RKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMVWSGTGMIMVSLPILTGSDVGLGTVPNLTTARISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMESNISLRAVPVVTPN--CDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIP-------RPVKDVPCMFYIPQRPYMSIGSLCDQIIY-RKHITENELRSILKMVSLEHIAQR--DSFDVVRDWKDI-LSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGM--GITLLTITHRPTLWKYHTHILEFDGLQFRKMNSDEEQKGQF................................... 728
13 -40.800[IR] KOG0060 Long-chain acyl-CoA transporter, ABC superfamily (involved in peroxisome organization and biogenesis)  ali follow..  15  20...........................................................................................................................APGVVGMLAVFALIKLYKQDIRGTKHLVAKTKKDGSKGQKAHVDGVFLGKLARILKILIPESFYLILIAVSLLCRTYADVYMIITSTKIEASII-DRNPLLFALEAFKYVLNLPAISVTNAILKFGIAELKLRFRERLSTHLYSQYLK-GFTFYKMSNLDTRIQLLTQDVDRFCDGIVELYSNLSKPILDVFLYLFRLGTSLGFSSPSILFSYLLFGVGLTYLRRPIGRLTVEEQALEGEYRYVNSRLIMNSEEIAFYQGNQSEKSTFASLVQHLRKIILFRGFVDNIVAKYLATVVGWYAVGSSFFDKQHKPFIGMSRNQLMQEYYMMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVLDDVNSAGSGNLRVQDNVIRFDNVPLVTPN--GDVLIERLNFEVPSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGTLTKPA-----------KGKLFYVPQRPYMTLGTLRDQIIY-RKGVSDSDLEQMLENVQLTHILER-EGGWSAVQDWMDV-LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGAMYRLCREK--NITLFTVSHRKSLWKYHEYSLYMDG................................................... 643
14 -38.900[H] COG3840 ABC-type thiamine transport system, ATPase component  ali follow..  30  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKLTDITWLYHH-----LPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGALTIDGVDHTTTPPS--RRPVSMLFQENNLFS-TVAQNIGLGLNAVQQEKMHAIARQMGIDNLMARLPG-----------ELSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSTSCQKMTLLMVSHSVEDAARATRSVVVADGRIAWQGMTNELLSGKASASALL............................ 228
15 -37.500[R] COG4178 ABC-type uncharacterized transport system, permease and ATPase components  ali follow..  15  47.............................................................................................................................................................................GRQYWRITRGYWLMLAVLLFSVVISVRLNVLFSYQSKDLYNALVKQSGMHGFWMSLGIFSILAVIFIARVMADIYLTQRFIIAWRMWLTNHLTTDWLDQR-AYYREQFIDNTIDRIQQDIDIFTAGAGTGSTLAVESVISVISFTAILWNLSGRLAVFEFEIPRAMFWIVIVYGRPLIGLNFANEKLNAAFRYALVRLRDAAEAVAFYRGEEAERKQLEQRFTPIIDNYRRYVSRTIRFLGWNASVSQTIVPLPWILQAPRLFAGKINLGDVGQTATAFGNIHDSLSFFRNNYAAFAAFRAAIIRLHGLVVANARSRELPHVTAKSTNDTVHVVAVEVRTSA--GEQLIDPLDLQLNCGSSLVITGRSGVGKTTMLRSLAELWPYASGTLSRPD-----------KNETMFLSQLPYVPLGNLRGVVCY-PADIPEDTVRDTLTKVALNPLCDRLDEERD------AKILSPGEQQRIAFARILLTKPKAIFLDESTSALDEGLEFALYQMLRSELPDCIIVSVSHRRAVELLHAQQLELLGG.................................................. 623
16 -36.300[E] COG1126 ABC-type polar amino acid transport system, ATPase component  ali follow..  28  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................INFKNVSKHF----KIQVLHDINLNITQGEVVVIIGPSGSGKSTLLRCINKLEVITRGQLIVDGLDVNSIDERQIRLEAGMVFQQFYLFP-TALENVAFGPTKVRGTSKEEAKKQA---ALLSKV--GLEDRAHHYPAELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPELRHEVLTVMKDLAEGMTMVIVTHEVGFAQKASRLIFIDKGRIAEDGDPDSLISN.................................... 226
17 -35.900[E] COG4161 ABC-type arginine transport system, ATPase component  ali follow..  27  3.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IQLNGINCFY----AHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFSDKAIRDLRRNVGMVFQQYNLWP-TVQQNLIEAPCRVLGLSKDQALARA--EKLLERL--RLKPYSDRYPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAENITQVIVTHEVEVARKASRVVYMENGHIVEQGDAS......................................... 226
18 -35.000[CP] COG4555 ABC-type Na+ transport system, ATPase component  ali follow..  19  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ITLTDCSRRFQDKKKVKAVRDVSLTIEKGEVVGILGENGAGKTTMLRMIASLLEPSQGVITVDGFDTVK-QPAEVKQRIGVLGGETGLYDRTAKENLQY----GRLYGLNRHEIKARIEDLSKRF--GMRDYMNRRVGGFSKGMRQKVAIARALIHDPDIILFDEPTTGLDITSSNIFREFIQQLKEQKTILFSSHIMEEVQACDSVIMIHSGEVIYRGALESLYESER.................................. 229
19 -34.700[P] COG1117 ABC-type phosphate transport system, ATPase component  ali follow..  29  18................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PHSLPAAMATEDLHVYY----DNHAIKGVDLTFPENKVTALIGPSGCGKSTYLRALNRMND-MEGQILYDGINIKEVDLYNVRKEIGMVFQKPNPFTKSIYENVAFGNKKEIMERVEKSLRRAALWDEVKD-------DLGKSALSLSGGQQQRLCIARAVAMQPKVLLLDEPASALDPISTSKIEDLINELKNKYTIIIVTHNMQQAARSDYTSFFYLGEVVEFSGTSELFTN.................................... 256
20 -34.600[R] COG4136 ABC-type uncharacterized transport system, ATPase component  ali follow..  24  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LCVKNVSLRL---PESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLFSWMIGALASCTGELWLNEQRIDILPTA--QRQIGILFQDALLFD-SVGQNLLLALPNARRNAVNDALERSGLEGAFHQDPA-----------TLSGGQRARVALLRALLAQPKALLLDEPFSRLDVALRDNFRQWVFSEVRAIPVVQVTHLQDVPADSSVLDMAQWSENYNK............................................. 215
21 -34.300[D] COG2884 Predicted ATPase involved in cell division  ali follow..  26  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ITLDHVSKKYKSL-ARPALDNVNVKIDKGEFVFLIGPSGSGKSTFMRLLLGAETPTSGDVRVSKFHVNKLPGRRLRQVIGCVFQD-LLQQKTVYENVAFALEVIGRRSDAINQVVPDVLETV-----GLSGKANRLPDELSGGEQQRVAIARAFVNRPLVLLADEPTGNLDPDTSKDIMDLLERINRTGTTVLMAHDHHIVDSMRRVVELSLGRLVRD-------EWCGIY................................ 225
22 -34.000[H] COG4138 ABC-type cobalamin transport system, ATPase component  ali follow..  23  14.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMT-SGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPFATPVWHYLTLHQHDKTRTELLNDVAGA-----------ALDDKLGRSTNQLSGGEWQRVRLAAVVLQAGQLLLLDEPMNSLDVAQQSALDKILSALCQGLAIVMSSHDLNTLRHAHRAWLLKGGKMLASGRREEVLTPPNL................................. 226
23 -33.900[E] COG4598 ABC-type histidine transport system, ATPase component  ali follow..  25  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LNVIDLHKRY----EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTIDKNQLRLLRTRLTMVFQHFNLWS-TVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKY----VHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEGKTMVVVTHEMGFARHSTHVIFLHQGKIEEEGAPEQLFGN.................................... 242
24 -33.800[P] COG3638 ABC-type phosphate/phosphonate transport system, ATPase component  ali follow..  23  6....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RKLTAADYPVVVQEPRKKVLAVKGLVKAYKS--QHRVLDNINFELHAGEFVAIIGRSGAGKSTLLHILNGTIPTSAGEIINDTQNIAALTTKQMRAKCGMIFQDFCLVPRDVITNVLLGRLSKSFFKLFSEQDQARAIELLQWL--NMLPHALQRAENLSGGQMQRVAICRAMMQNPKILLADEPVASLDPKNTTRIMNTLQKISEDIAVIVNLHSVDLVKDCTRVIGIAHGRIIFDGPPSMLNDS.................................... 263
25 -33.500[P] COG1121 ABC-type Mn/Zn transport systems, ATPase component  ali follow..  25  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKVENLTVYQGNYL---AIRDVSFNLLPGTDTAIVGPNGAGKSTLVKAILDLIPRRVGQIEIFGRPITKL--GNLRHLLGYMPQNFIFFPISVEELVGLGWSREKSAAIATALKRTDTYHLR-------NQAIGT----LSGGQLKRILLAYCLVIPRKILVLDEAFAGVDMQGAADFYAMLNELKQGWTVLQVSHDIDMVSRCDRVLCLNQ-TVVCTGQPEIALSPQNL................................. 242
26 -33.300[V] COG4167 ABC-type antimicrobial peptide transport system, ATPase component  ali follow..  23  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEVRNLSKTFRRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPS---TSLNPRQRISQILDFPLRLNTDLEPEQRRKQIIETMRGLLPDHVSY--MLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEGISYIYVTQHIGMMKHSDQVLVMHQGEVVERGSTADVLAS.................................... 241
27 -33.300[P] COG4559 ABC-type hemin transport system, ATPase component  ali follow..  23  8.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IRVTDLSYSVAGRE---LLSKLKFHLQSGEMLAVLGRNGAGKSTLLKHLTGELGK--SGVELFGQPLRDIKPAEAAKRRAVLPQQTPLFAYEVLDVVLLGRETVQDRAIAAACLER-----------GLSGYETRDVLTLSGGEQQRVHFARTLAQGERVLLLDEPTASLDLAHQHATLRLARELCEGVGVLAVLHDLNAAQYADRVLMLAEGHVIACDHPAVALTPESI................................. 236
28 -33.300[P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component  ali follow..  21  12.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EPHPTAIELKDVQISFRLAGRFDAVAESNLAVAENEFVAIVGPTGCGKSTLLNAVAGLLTPASGTVEISGQRLQGLNR-----KAGYLFQQDALMPKTVLENVAIGLE----AGTPKAKAREQAREWLNKV--GLGTFGDRYPHMLSGGQRKRVGLAQVLIRNPKYLLMDEPFGPLDAQTRVIMGDLLLDLWSKKAVMFVTHDLEAIALADRVVIMSRARIMAE............................................. 234
29 -33.300[P] COG4604 ABC-type enterochelin transport system, ATPase component  ali follow..  21  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IEINDVNKKYQQT---TVLNEINERIPSGGITSIIGPNGAGKSTLLSIMSRLLAADSGNVLFNGLDVAKTSGDKLATILSVLRQENHFTSRTVSDLVGFGRNKNDRQHIDAAMEFLNLMPLKDRYLD-----------ELSGGQRQRAYVAMVLCQDTSYILLDEPLNNLDMKHCVAMMKQLRRAADHKTIILVIHDINFASASDHIIAMKNGEVIYRGAPAEIMQPSIL................................. 229
30 -33.200[P] COG4525 ABC-type taurine transport system, ATPase component  ali follow..  27  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LNVSGLWAEYQG---KPALQDVSLQIASGQLVVVLGPSGCGKTTLLNLIAGFMTPSAGVITLDNIPVSGPSAE------GVVFQNEGLLP-DVVSNVEFGLQ----AGMSKEQRRVTALKMLNRV--GLAGFEHHFIWQLSGGMRQRVGIARALAVDPRLLLLDEPFGALDAFTREQMQELLLTIWRGKQILLITHDIEAVFLASELLLLSPGQVVER............................................. 212
31 -33.100[P] COG4107 ABC-type phosphonate transport system, ATPase component  ali follow..  24  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LQVHELSKSYGG---IKACDRISFDLYPGQVLGIVGESGSGKSTLLGAIADHIAVDHGNVTYISRSGEDLEIFQLRTEWGFVQQNPR---DGLRMRVSAGANIGERLLDIGVRHYGNIRDEAAHWLREVETRIDDLPAQFSGGMQQRLQLARVLVTRPRLILMDEPTGGLDVSVQARLLDLLRSLVRHLSVIIVTHDIGVVRLAHRLLVMQQGQVVESGLTDQVLDD---YTQLL............................ 250
32 -32.400[Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component  ali follow..  26  7.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VEVHRLRKSVGQGEELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGKPLHQMDEEARAQHVGFVFQSFMLIPTNALENVELPALLRGENS---GQSKAGAKALLEQL--GLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNRGTTLILVTHDPALAARCDRRLRLVNGQLQEEA............................................ 228
33 -32.300[P] COG1135 ABC-type metal ion transport system, ATPase component  ali follow..  26  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IEIKSVNKVFYQGDQIHALKDINLFIPQGTIFGVIGSSGAGKSTLIRCVNMLEKPTSGQVIVDGVDLTTLSNPQLRRNIGMIFQH-LLSSRTVFENVALPLELAGQSQQHIETKVTELLALV-----GLSEKRESYPANLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILELLKEINRNLTILLITHEMDVVKSCHEVAIIGGGELVEKGTVGDIFAH.................................... 231
34 -32.200[E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components  ali follow..  29  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MQPVVHFKNVNKYY----GLPAVDDLDLAVESGQFVTLLGPSGCGKSTTLRMLGGFEQPSSGEIYLEGKPITHLPPN--RRNVNIVFQDYALFP-NVGRNIAFGLELKGLSSDAIHKRTMELLALVK-----LQDFADRMPDQLSGGQRQRVALMRALAPDPNVLLLDEPLSALDAKLRQQMQIELKTIQRGKTFIFVTHQEEALTMSDVIVVMNKGRIEQMGGPNELYSR.................................... 225
35 -32.200[V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component  ali follow..  22  5.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEVKHINKTYKGQVSYQALKQISFSIEEGEFTAVMGPSGSGKTTLLNIISTIDRPDSGDILINGENPHRLKRTKLRKQLGFVFQD-LLDTLTIGENIMLPLTSVMEEKLHGIAAKLGIENLLNKRT-----------FEVSGGQRQRAAIARAVIHKPSLILADEPTGNLDSKATKDVMETLQSLNRDDTALMVTHDPVSASYCRRVIFIKDVVLFNEIYRGE--NRQVFYEQILD........................... 240
36 -31.700[RK] KOG2355 Predicted ABC-type transport, ATPase component/CCR4 associated factor  ali follow..  16  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AEKDATASGDDAIRVSGMQFAYEV--EDPIFFDFNLDLPAGSRCLLVGANGSGKTTLLKILAKHMVGGKNVVQVLSRSAQLVCSGDLSYLGGSWSKTVGSAGEPLQGDFSFGVEGTDPVRREKLIDL-------------LDINLQWRMHKVSDGQKRRVQICMGLLHPFKVLLLDEVTVDLDVVARMDLLEFFKEECDQRTIVYATHIFDGLETATHLAYIQDGELNRLSKMTDIEELKT.................................. 241
37 -31.600[E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components  ali follow..  25  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IELDKLSKTFTNGKEFRAVDSVSLTVEKGEICVFLGPSGCGKTTTLKMINRIIPPTSGRVLIDGQDTADLDEVTLRRHIGYVIQQIGLFP-TIEENIMVVPRLLGWDKARCKEKARELMSMVKLEPKQY---LQRYPRELSGGQQQRVGVIRALAADAPLLLMDEPFGAVDPINRESIQNEFFEMQRGMTVIMVSHDIEAIKLGDKVAVFKSGRLLQYDHPDTLLAH.................................... 231
38 -31.200[Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component  ali follow..  23  7.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IEVKGLTKSFGSS---RIWEDVTLDIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELRTLFGVLFQDGALFGSNLYDNTAFPLREHTKKKESEIRDIVMEKLQLVGLGGDEKKFPGE----ISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDINADATILIVTHNVNIARTPDNMGMLFRKHLVMFGPREVLLTSDEPVVR----QFLNGRRIGPIGMSEEKDESTMA... 262
39 -31.100[P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component  ali follow..  30  2......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SIEIANIKKSF----RTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHAR--DRKVGFVFQHYALFR-TVFDNIAFGLTVLPRRERPNAAAIKAKVTKLLEMVQ-LAHLADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEKFTSVFVTHQEEATEVADRVVVMSQGNIEQADAPDQVWRE.................................... 227
40 -31.000[PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components  ali follow..  21  5......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AISTETLSLGYGDA---VIIDELNLTIPKGEITVFIGSNGCGKSTLLRSLARLMKPRGGSVLLEGRAIAKLPTKEVAKELAILPQGPSA-GLTVHQLVKQGRSKEDEEAVERALKATKLEDMADRAVD-----------SLSGGQRQRAWIAMTLAQETDIILLDEPTTYLDMTHQIEILDLLFELKEDRTIVMVLHDLNACRYAHHLVAIKDKRIYAEGRPEEVITCD................................... 233
41 -30.800[P] COG4778 ABC-type phosphonate transport system, ATPase component  ali follow..  23  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................INVQNVSKTFQNGVRLPVLNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIEWVDLVTAPARKVKTTVGWVSQ--VIPRISALEVVMQPLLDTG---VPREACAAKAARLLTRL--NVPERLWHAPSTFSGGEQQRVNIARGFIVDYPILLLDEPTASLDAKNSAAVVELIREATRGAAIVGIFHDEAVRNDADRLHPMGASS................................................. 226
42 -30.000[Q] KOG0061 Transporter, ABC superfamily (Breast cancer resistance protein)  ali follow..  24  67.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LSFDNLTYNVSVRKTKTLLNNISGETRDGEIMAVLGASGSGKSTLIDALANRIAKGKGTVKLNGETL---QSRMLKVISAYVMQDDLLFPMTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQIRNAAKTIIGDRG--ISGGERRRVSIGIDIIHDPILLFLDEPTSGLDSTSAFMVVKVLKRIAQGSIVIMSIHQPSHLGLLDRLIFLSRGHTVYSGSPASLPR..................................... 323
43 -30.000[EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component  ali follow..  27  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEIRNLSRCFPIHNAVRAVDDVSFYIERGAVYGLAGESGSGKSTIARLIMGLEKPSCGEIRIDGEMIAAGHSRAHGKKVQMVFQNPG---SSLNPRRTVGQSVAVPLDAHGFPSLQRAKRISELLE-QLPANFAER--ELSGGQKQRVAIARALAVAPKLLVLDEPTSALDVSVQAKVIDLLVDLGRDLTYLFISHDLSLMRNASRVGILYRGKLVETGKTDEVFYR.................................... 242
44 -29.900[R] COG1101 ABC-type uncharacterized transport system, ATPase component  ali follow..  22  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IRLQDITFNPGTILENRALRGVSLEVPEHQFLTVIGSNGAGKSTLLGAVTGETPIVGGQVLIDEIDVTKQSVDQRANLCARVFQDPLAGTCTIEENMALAYMRGKKRGWSLALSNQRRKLFISILGLGLEDRLGDNIGLLSGGQRQAVSLVMATLSESKLLLLDEHTAALDPRMAAFIIDLTKKIVKEFTVMMVTHSMKALACGDRTVMLHQGQIV-TGEQRANMGVPELLEMFSKVR......................... 252
45 -29.800[E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component  ali follow..  18  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKLASISKRF----GLSVLQDVNIEVPQGTIFGLIGPNGAGKTTVFNLITGLLEPTGGTLTFGGTSLVGKKPHQITQMIARTFQNIRIFKETLLENVVVGMHRHLDYGAPGLRARDRALELLSWV--KLDHKAGDIADNLSYGDQRKLELARALATEPKLLLLDEPVAGMNTGEKVDLMAEIENIRAGYTIFMIEHDMRFVMGCERIAVLNFGRIIAEGPPEAIRNNPQVIEAYLGRDDDDGEGGAAAQEVTA.......... 265
46 -29.600[R] COG1137 ABC-type (unclassified) transport system, ATPase component  ali follow..  25  4.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LTAENLAKSYKSR---KVVSDVSLTVNSNEIVGLLGPNGAGKTTTFYMVVGLVRQDQGKIVIDGEDISLLPHNRAQRGIGYLPQEASIFRRTVYENLMAVLE--IRKDLTPQQRREKADELIEEF--NISHIRDNLGQALSGGERRRVEIARALAANPKFILLDEPFAGVDPISVSDIKKIITDLRRGLGVLITDHNVETLDVCERAYIVGAGKIIATGTPEQVMNDEQVKRVYLGEQFK....................... 240
47 -28.700[R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase  ali follow..  17  94................................................................................................................................................................................................................................................................................SIILNKADGSSVDLAKLDPRGRAIRAVRGADIAMIFQE----------MSSLSPVHTVGDQITEVLRL---------------HLKMSKAQARAEAIELLRQVEIPNPEKALDRYAFQYSGGMRQRAMIAMALACKPQLLIADEPTTALDVTTQAEILDLISRLQKAHGMAVL--FITHDMGVVAQIADVLVMHHGVVKEYGTVEQIFHLIGSVLKLEQKAEIRLARPPLDLEVKDLSMHF---GEMKALDGVSIKLLPGETLGIVGESGSGKTTMGRSIMRLYDPTAGEMLYRRADIEGKELKAARRELRMVFQDPF---GSLNPRMTVAQVIGEPLLVNGIAKGKELEERVCSLMEGLDPSGRER--AFSGGQRQRIGIARAITLRPRIIVADEATSALDVSVRFQVLDLLMKLQDGLAYIFISHDIGVIRYCDRVGVMYRGKLVEVGEAEKVCNA.................................... 549
48 -28.500[E] COG4608 ABC-type oligopeptide transport system, ATPase component  ali follow..  28  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEVKNLTKSFDINGGVRAVDNLSFSVYEGEVLGIVGESGCGKSTTGKAILRLIEPSSGEVYFAGTEITALSEGDMRRDMQIIFQDPY---ASLNPRHTIEKIIREPLIVHQIGTKKEQLERVEELLEGLSSDHATR--QFSGGQRQRIGIARALAVHPKLVICDEPVSALDVSVQSQILNLMADLKEALTYIFIAHDLSVVKHSDRVAVMYLGRMVEMATKDQLFEN.................................... 246
49 -28.200[R] COG2401 ABC-type ATPase fused to a predicted acetyltransferase domain  ali follow..  16  115...............................................................................................................................................................................................................................................................ERIAELEQYHYAS--KSKVALWKCYDCGNL---IEANTKPVCECGSRNVHIVIKGSTPASRFLIFELVFEPEVVAYVRVDPPVPLMHRKLDGKIVENIRERVKEWFENVFSPEKELSELFRKLRSFSLKVARHRLWEEASEEAMKKCNSAASRIARVVVADGLGILAVRTAVEWIEERRVPEMRMTIAQMARFNPFFEKAGDTASGKPVLYKPLSEE--AERYIRKFLEEDEVARGHGGKLCVSRYGSLKFRNVSKLFASTLDLEVLRDVNLEIKPGEIVAVVGASGSGKTTFLRLIVGEALKLDDDVYKPSSGMVEVV----VDSIAAMIPSELEPQITEKSIL--------EQIFDITGDIHLAVEVLNRAGISDAVLYRARFNELSTGQKERFKLAACLAKKPSLMLVDEFAAHLDEMTAVRVARKISELARKITLIAVTHRKEVINAPDRILYVGYGGVTES............................................. 619
50 -28.000[E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component  ali follow..  22  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LSFDKVSTYYGK---IQALHDVSVEVKKGEIVTLIGANGAGKSTLLMTLCGSPQAASGSIRYEGEELVGLPSSTIRKSIAVVPEGRRVFSRTVEENLAMGGFFTDKDDYQVQMDK------VLELFPRLKERYEQRAGTMSGGEQQMLAIGRALMSKPKLLLLDEPSLGLAPIIIQQIFEIIEQLRREGVTVFLVEQNAALKLADRAYVLENGRIVMHDTGAALLTNPKV................................. 226
51 -27.800[G] COG3839 ABC-type sugar transport systems, ATPase components  ali follow..  28  4.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SFLKITDLYKSYG---SVSVLKDINIEIDEGGFLVLVGPSGCGKSTLLNTIAGLEPITSGDIAINGKSVSNLHPSQ--RDIAMVFQSYALYPNTVAGNIAFGMEPERDKAIQQVADMLQIGHLLDRKPS-----------QLSGGQRRRVAMGRALVRNPQVFLFDEPLSNLDAKLRVDMRTEIKRLHSKTTIVYVTHQIEAMTLATKIAVLKDGVLQQFGTPAEIYNN.................................... 226
52 -27.700[E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component  ali follow..  27  4......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KLEVKNLYKIFGEHPQRAFVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRKKIAMVFQSFALMPMTVLDNTAFGME----AGIAAQERREKALDALRQV--GLENYAHAYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAQRTIVFISHDLEAMRIGDRIAIMQNGEVVQVGTPDEILNN.................................... 255
53 -27.300[V] COG1131 ABC-type multidrug transport system, ATPase component  ali follow..  23  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MPSILSISGVSKTYAT--GFTALKEVNLDIQRGEIFALLGPNGAGKTTLISIVCGIVNRSTGTVTVDGHDIGK-DYRAARSLIGLVPQE-SVWATVNYSRGLFGKP----------PNHGFVEKVLRDL--SLWDKKDAKAITLSGGMKRRLMIAKALSHEPRILFLDEPTAGVDVELRQDMWEMVRRLEDGVTIILTTHYIEEAEAADRVGVINRGEIILVENKAELMHKLGRKRLVLELR......................... 235
54 -27.100[O] COG4133 ABC-type transport system involved in cytochrome c biogenesis, ATPase component  ali follow..  23  10..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDGDTAQCLEALAQAGLAGF-EDIPVNQ----------LSAGQQRRVALARLWLTRATLWILDEPFTAIDVNGVDRLTQRMAQTEQGGIVILTTHQPLNVAESK.......................................................... 193
55 -27.000[R] COG4152 ABC-type uncharacterized transport system, ATPase component  ali follow..  20  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LTIDHVTKTF----DYKAVDGLDLDIPEQQMFGLLGANGAGKTTTFRMILGLLSITEGSISWKGRPVNYHI----SNKIGYLPEERGLYPKKVRDQLVY----ARLKGMEKREAVKELGTWLERF--NITDYENKKVEELAKGNQQKIQFISAVLHKPELLILDEPFSGLDPVNVELLKEAVISLKSGVSILFSSHRMEHVEECENLCILQKGKPVVQGKLKEIKRSFG.................................. 221
56 -26.700[R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component  ali follow..  18  26............................................................................................................................................................................................................................................................AVKGINIHVNAGETVAVVGESGS--GKSQTMMAAMSLLASNGEATGSVGRNLLTLSKSDLNKVRGAKISMIFQEPMTSL-----PLYSIGNQLIEPIRRHRGLNAAEAREEALKLLRLV-DPERRMKSYPHEMSGGQRQRVMIAMALANDPDILIADEPTTALDVTIQAQIL--------MLLAELQRKLGMAIVFITHDLGIVRRFARVYVMRQGEVVEEGEAGAIFALLAAEPT--GSKAAPPANAPVVLEGRHVEVTFKIGGGLRAVDDISIRLQRNQTIGIVGESGSGKSTLGRALLRLL-PSDGLIRFGDRDISTADRQAMRRQMQLVFQDPF-VGQVITEGLLVHEPNLSGKQ-----RDQRAVEALREV--GLDPNARNR--EFSGGQRQRIAIARAMILKPKMVVLDEPTSALDRSVQKQIVELLRKLQAELSYLFISHDLSVVRAADYIIVMKQGKIVEEGPTEAIFSN.................................... 516
57 -26.600[P] COG4148 ABC-type molybdate transport system, ATPase component  ali follow..  25  16...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICKRRVGYVFQDARLFP-KVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPG-----------SLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTRE-PMLYVSHSLDEILHADRVMVLENGQVKAFGALEEVWGSSVM................................. 222
58 -26.100[EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component  ali follow..  23  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MMSLLDVKDLRVEFSTQDIVTAVNDLNFSLKQGETLGIVGESGSGKSQTVFAIMGLLAKNGGSAKFEGKEILNLPERELNKQIAMIFQDPM---TSLNPYMKVSDQLMEVLMLHKGMGKAEAFEESVRMLE--RKRITMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMELLNELKRNTAIIMITHDLGVVAGCDKVLVMYAGRTMEYGSVNDIFYNPGLLSAIPRLDTEGEV.................... 266
59 -26.100[V] COG4170 ABC-type antimicrobial peptide transport system, ATPase component  ali follow..  22  4.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LDIRNLTIEFMTSEGVKAVDRISMTLTEGEVRGLVGESGSGKSLIAKAICGVSKDTADRFRFNDIDLLQLTPRQRRKNISMIFQEPQSIGLQLIQAIPGWTYKGRWWQRFHWRKRRAIELLHRVGIKDHKDIMHSYPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNTTILLISHDLQMMSKATRVNVLYCGQTVESAVCEDLLST.................................... 249
60 -25.900[J] KOG0066 eIF2-interacting protein ABC50 (ABC superfamily)  ali follow..  17  503.............................................................................................................................................................................................................................................................GWRMRVSLARALYLTLLMLD----------EPTNHLDLNAV-----------IWLDNYLQGWKKTLLIVSHDQSFLDNVCNEIIHL---LQYYKGNYSMFKKMYVQKRREMIKEYEKQEKRLRELKAHGQSKKAAEKKQKESLTRKQEKNKSKQQKQ--------------------------------------------------DEDEGPQELLARPKEYIVKFRFPEPSQLQPP------------LGVHNVTFAFPSQK--PLFIKVDFGIDLTSRVAIVGPNGVGKSTFLKLLLGELEPQEGEQRKNH-----------RLHVGRFDQHSG-------EHLTAEESAAEYLQRLFNLPHEKARKALGSF--GLVSHAHTIKMKLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEAINE---EGGVIIVSHDERLIREGCTLYVIEDQTINEVGEFDD-------YRKEVLDSLGEVVNNPSVVANAA.......... 898
61 -25.300[R] COG4674 Uncharacterized ABC-type transport system, ATPase component  ali follow..  18  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEIQDLTVSF---DGFRALNHLTFSMNPGELRVIIGPNGAGKTTFLDVITGKVQPTEGRVLFQGKDIRKIPEYRIRLGVGRKFQTPRVYLNTVAENLDLAVNRKKS---ATGAEQRSVGGLLETI--GLTPKAHLAAALLSHGEKQRLEIGMLVAQSPTLLLVDEPVAGLTDEETENVGDLLLALAESHSIIVIEHDMEFVRQARKVTVLHQGSVLCEGNMDQIQNDPKVIEVYLGEAPSLSPQQFKILRTVAAVAAADGKIS 271
62 -24.700[R] COG4586 ABC-type uncharacterized transport system, ATPase component  ali follow..  22  2..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................VENLSKVYPIALKSPGLKGTLQHFWQRR-----------------------------YRQILAVQDISFTIPPGAMVGFLGANGAGKTTTLKMLTGLIKPSGGKVRVAGFDPFRRQTAFLRRTSLVMGQKQQLI---------WDLPTLDSLRINGAIYEIPDQVFEQRLGEDLTTELKQPVRKLSLGQRMKAELLAALLHHPTVLFLDEPTLGLDVNAQVAVRRFLQEYNRQATVLLTSHYMADITTCERVLLIHQGQLMYDGDLEALVERFSPYRQVA............................ 251
63 -24.700[A] KOG0063 RNAse L inhibitor, ABC superfamily  ali follow..  15  209........................................................................................................................................................................................................................................................................................................................................................VLEREARQVSGGELQRFAIAAVFVKKADIYMFDEPSSYLDVRQRLKAAQVIRSLLRHDSYVIVVEHDLSVLDYLSDF-----VCCLYGKPGAYGVVTL-----------------FSVREGINVFLAGFIPTENLFRDESLTFRVSETTQENDGEVKSYARYKYPNMTK--QLGDFKLEVMEGEFTDSQIIVMLGENGTGKTTFIRMLAGAFPREEGVQSEI----PEFNVSYKPQGNDSKRECTVLLHDKIRDACAHPQ---------------FMSDVIRPL--QIEQLMDQVVKTLSGGEKQRVAITLCLGKPADIYLIDEPSAHLDSEQRITASKVIKRFILKKTAFIVEHDFIMATYADRVIVYEGQPAVKCIAHSPQSLLSGMNHFLSHLNITFRRDPTNFRPRINKLESIKDKEQ 592
64 -24.200[O] COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component  ali follow..  21  2.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LEIRNLHARI-VDDGTEIIRGLNLTVKAGEVAAIMGPNGSGKSTLSYILA--YEVTEGDILYNGQSILEMDPAEATSGIFLAFQYPMEIPG---ATMEFLKVAMNEQRKARGEEPLKIPEFLKRVKENMDMAMLKRPLNFSGGEKKRAEILQMKLLEPKLCVLDETDSGLDIDALKIVSDGVNALRADRAFLVITHRLLEHIVPDSVHVLYRGQVIKSGDKS......................................... 233
65 -23.600[R] COG1245 Predicted ATPase, RNase L inhibitor (RLI) homolog  ali follow..  16  200........................................................................................................................................................................................................................................................................................................................................................VVERKISELSGGELQRVAIAACAARDA-------QFYFFDEISPYLDIYQRINVARLVQEISKDRAVLVVEHDLAILDMLTDVIH----------IAYGEPAGFGVITLPKSVR-VGINQYLKGYLPEENIRIR-----PEAIRFEVHPPREDAQFQSMVSFNSFSKQY---GDGFSLKATGGSLREGEVLGIVGPNGIGKSTFVKVLAGEIKPDEGDPGIEVK----------------ISYKPQYIKADTPVSVQDFLRGITKR----FGTSYYEVEIANPL--QLERIYESLLTELSGGELQRVAIAACLSQEADLYILDEPSAHLDVEQRSMVTKVINRFAEQKTAMVVDHDIYMIDMSQRLLVFEGKPSVYGEAHGPFSMESGMNRFLENLGITFRRDEETRRPRVNNLGSRLDREQ 576
66 -23.200[P] COG1122 ABC-type cobalt transport system, ATPase component  ali follow..  17  8.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IELRVDKYTYPNG--RVGLSDFYATFEGCD--FIIGPTGSGKSTVLKMVNGLIPNLEGKVRVFGEKPN-------PRIAFFVKQNPMITSTQVIDELVFPLIQQGFGWGEAKREAEEVCEEL-----GIGGLLERKTYELSTGELQLVQIAAALASKARILVFDEPFANLSRKNVLKVIKIL----RDYPHLVSEHRLEFSSFEKTINLGLECEDLREGELIALVGDNGAGKTMMLKKIAT...................... 254
67 -22.600[G] COG1129 ABC-type sugar transport system, ATPase component  ali follow..  16  138....................................................................................................................................................................................................................................................................................................................................................................................................................................................TATLTPSETEHLFNVMRELRRQGVAIIFISHHLDEIFEICDRITVLRDELIGSCLTSEVDNDRLVEMMVGRRIEASFPPKPQIDGGPVSRFSLRKGEILGFAGLVGSGRTETVLAMLGAHSASRRKIKLDGVDTRLSGPDDALMRIGLLPES-LITSFSILQNISLNNYRKYRKALDLKKELEHTTKAMAQVQQGPYARVDT----LSGGNQQKIVIARWLNHDMRVLIFDEPTRGIDVGAKAEIYSLMREFARGHSIIMISSELPEVIGSDRVCVFRSGGIVATVEGEDI-NSETIMTNATTGRVEH...................... 470
68 -22.200[P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA  ali follow..  19  44....................................................................................................................................................................................................................................................................................................................................SGKSALARALALPLLKGERQSQFSHITRLSFEQLQKLVSTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGI--TPLLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGTLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRP---ILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGSNDLTLFGRRRGSGETIWIKKHIGYVSSS----STTVRNVILSGYFDSIG-QAVSDRQQKLVQQWLDIL--GIDKRTADAPFSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISETQLLFVSHHAEDAPACHRLEFVPDGGLYHYALTK......................................... 492
69 -22.100[EJ] KOG0062 ATPase component of ABC transporters with duplicated ATPase domains/Translation elongation factor EF-3b  ali follow..  16  7.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IVNTDFSLAYGSRM---LLNKTNLRLLKGHRYGLCGRNGAGKSTLMRAI------ANGQL--------DGFPDKDTLRTCFVEHK------QGEEGDLDLVSFIALDEELQSTSREEIAAALESV--GFDEERRAQTVSLSGGWKMKLELARAMLQKADILLLDEPTNHLDVSNVKWLEEYLLE-HTDITSLIVSHDSGFLDTCTDIIHYENKKLAYKGNLAAFVEQKP--EAKSYYTLTDSNAQMRFPPPGILTGVKSNTRA 245
70 -21.600[R] KOG0927 Predicted transporter (ABC superfamily)  ali follow..  15  151....................................................................................................................................................................................................................................................................MEVDEERIKLEKLAEELAMSEEDDAQEQLIDIYERLDDMSADLAEVKAARILHGLGFDKAMQQKQAK-MRIALARALFVKPHLLLLDEPTNHLDLDACVWLEEELKTYKRILVLISHSQDFLNTGKRLKYYTGNYEAFVRTRMELLENQM----------------------KQYNWEQDQISHMKNYI----------ARFGHGSAKLARQAQSKEKTLAKMVAQGLTEKVSDDKVLNFY--IMVQNVNFRYNDETPW-IYKNLEFGIDLDTRLALVGPNGAGKSTLLKLLYGDLVPTSGMIRKNS-----------HLRIARYHQELLDLDASPLEYMM--------RAFPDVKEKEEMRKIIGRY--GLTGRQQVCPIRLSDGQRCRVVFAWLAWQVPHLLLLDEPTNHLDMETIDALADAIND---DGGMVLVSHDFRLINQAEEIWVCEKETVTKKGGILD-------YKDHLKNKITSENEKKAKAGK............ 611
71 -20.700[R] COG3845 ABC-type uncharacterized transport systems, ATPase components  ali follow..  24  6.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IELIGINKSFGA---VRANRDINLEIARGTIHGIVGENGAGKSTLMSILYGFYQADSGEIRVGGKPASIKTPNDIALGIGMVHQHFMLVDNSVLENIILGAESDALLKS----SIAKARSELERLEREYGLEVDPDAIELPVGLQQRVEILKALYRGAEILILDEPTGVLTAEADHLFRILKQLKEQGKTVVLITHKLREIMATDNVSVMRQGTMVATRETSKTTVGE................................... 232
72 -19.200[GM] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component  ali follow..  16  58.....................................................................................................................................................................................................................................................................ESKIVWPLRNLDFTGYKGEILGIIGSNGAGKTTLCK--MLSGILKPDEGELYVDGRVSALFSLGMGFK---LTGRENAYLNGMMLGIEKDQIDQFIDEIH----------------------EFSGLGSFIDQPMKYYSSGMKARLGFS--------------VAAFLEPEILILDEALNTGDAA----FGKKAAAKMKELVSKAKMVILVTHSLRYARKNCDRLLWLDRGEIRAIGEPAEVIEKYKETIPVKVRRPRKALKNVSFDIKEGEVVGIIGHNGAGKSTLCKLLTKILTPDEGELELSGETTSLLSYGT---NAQLSGKDNVYLNGML-----LGIPKERAQEYPNIVAFSELEKHMDKPVKSY-----------SSGMKSRLGFSIAATLQPDIFIIDEALSTGDVAFQQKASEKIQEMMEAKAVIIVSHSMKFVESCTRAIWLEKGQVRFDGDPEEAVKL.................................... 503
73 -18.000[R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains  ali follow..  22  7.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YTMHRVGKVVP--PKRHILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPQP-------------KIGYLPQEPKL-QQTVREAVEEAVSEVKNANLEAIIQAHDGHNLDNQLERAADAL-DAKIEHLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDYEG--TVVAITHRYFLDNVAGWILELDRGEGIPEGNYSSWLETENARQKSIAKELEWVRQNPKGRQAKSKARMARFDE. 297
74 -16.500[L] COG0178 Excinuclease ATPase subunit  ali follow..  17  357.........................................................................................................................................................................................................................................................FKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKSNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQI----AEKVMKEINDRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMAD-----------HVIDIGPGAG----VHGGMVVAEGNVEEIIQYLSGVKKIAVPEQRTPKDAKKTVELKGAV-----------LKNVDLSIPVGLFTCVTGVSGSGKSTLINDTF--LEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTFSFNVRGGRCEACQGDGVIKVEMEDAREFFDPVPVSY-IRLGQSATTLSGGEAQRVKLARELSKRDTLYILDEPTTGLHFHDIQQLLSVLHRLRHGNTVVVIEHNLDVIKTADWIIDLGGGLIIAEGTPEDVAQIEASHT............................... 931
75 -15.200[R] COG3910 Predicted ATPase  ali follow..  14  18...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EYP---SVPAMRHLERLEFKTPITFFAGNNGSGKSTLLEGLAAGMTAYAIGNHGDVKGDLYLQHAETYPKIRMFLRAEDVLGIRRQNENALDDFRWEREKALKKGEDFPEE------EIFRGIVRNNSLDRRSHGE-GFLDIMHRRLHGAGLYFLDEPESPLSPQKQLELAAIIRQAADSGGQLIIAHSLLAIPEAT-IYYFDEDGITERLYDE......................................... 238

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]