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Query: [E] COG3483 Tryptophan 2,3-dioxygenase (vermilion), from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCPCPHSQAQGETDGEAEWHNAALDFTHAMSYGDYLKLDKVLDAQFPLSPDHNEMLFIIQHQTSELWMKLMLHELRAAREHVKSGKLGPALKMLARVSRIFDQLVHAWAVLATMTPTEYNTIRPYLGQSSGFQSYQYREIEFILGNKNATLLKPHAHRAELLAALEQALHTPSLYDEAIRLMAAQGLPVSQERLARDAAAGTCYEASVEAAWRQVYQAPERYWDLYQLAEKLIDLEDSFRQWRFRHVTTVERIIGFKPGTGGTEGVGYLRSMLDTILFPELWRLRSNLLast
1 -121.000[E] COG3483 Tryptophan 2,3-dioxygenase (vermilion)  ali  100  1MCPCPHSQAQGETDGEAEWHNAALDFTHAMSYGDYLKLDKVLDAQFPLSPDHNEMLFIIQHQTSELWMKLMLHELRAAREHVKSGKLGPALKMLARVSRIFDQLVHAWAVLATMTPTEYNTIRPYLGQSSGFQSYQYREIEFILGNKNATLLKPHAHRAELLAALEQALHTPSLYDEAIRLMAAQGLPVSQERLARDAAAGTCYEASVEAAWRQVYQAPERYWDLYQLAEKLIDLEDSFRQWRFRHVTTVERIIGFKPGTGGTEGVGYLRSMLDTILFPELWRLRSNL 288
2 -5.780[S] COG4843 Uncharacterized protein conserved in bacteria  ali follow..  71.............................IAYAVGYGIGVITGMKVEEKLALGYITVNVITKEYEPDIPNTLRDKGYGVTNWVAYGREGERLMMEILTS--KSEADLYATIKKLDPKAFIISHEPKTFFGGFWVKGIRR..................................................................................................................................................... 179
3 -5.600[R] KOG4198 RNA-binding Ran Zn-finger protein and related proteins  ali follow..  2................SKLPSPTMPLPESVGDLVVLHFETNLDDHGISIGRAPCEIHEICWVILDGKTLEKQHCESCSIR--EDSSRHGICGSASSLTEAIFTLDNSIQERLNFQGKPFTELRVLLPKEARDQGITLPYTITLSHIFGKLDVDSLPPITESKAIELSPSDAPYITKGLTQCWRLANATTLLLRKAEKDSRGHSLPSVLTQPINCQADARSFYAERSKIVAGLVTQLELESWFTNHGVHPVALWTLKTPEPYKSTGTGFVL-------FASHEDAADAL 303
4 -5.590[D] KOG4842 Protein involved in sister chromatid separation and/or segregation  ali follow..  10  514.....................................LQMLLKIVRNIIEQPNEMKFKRLRKGNPA-IKRNILNFPAAVEIL------SVVGFVDEMVSESTGAQEPYLVLKRNDPGLLWIAKSMIEESHPTAISIDSFREDKLQHTMEAENPSLGIQGNSHEDNKEDPRPILDCKAVISLDVKPLREVRDGEIFEFEGEEDEIDIEENSEEEEGYNSSSSQDESATHSSEALDIEKMIRTTHENGMRCTFIDL-VRAISLDTSFLEAWEKFSVKRLFMEIYISKDCV 764
5 -5.570[S] KOG3444 Uncharacterized conserved protein  ali follow..  10  50...............................FVTNTRVKFIVVIDSSNVALRENEVRAIFRNLHLLYTDAICNPFYIPGESLTSKKFDRAVQKLMS................................................................................................................................................................................................ 114
6 -5.390[NUO] COG1516 Flagellin-specific chaperone FliS  ali follow..  16  21............................................................AKLIEMLYEGILRFSSQAKRCIENEDIEKKIYYINRVTDIFTELLNILDY.................................................................................................................................................................................. 70
7 -5.350[S] KOG0396 Uncharacterized conserved protein  ali follow..  11  1.....................................MSEIKALEHATLKVPYEMLFRSAQKIIDREVDQVINVSRQVEKALEAEEGPILAEVTKLVDNVAQKLQVLKRKAEESINDELSVTQICKRKLDHLKGIT----------------PPSSVTGDLWQGSVDQWKRIRLDRLVIEHLLRMGYYETAEELAAKSDVRHLTNLDIFQTSREVEDDLASH----STTKCVLWCIDNKSKLRKINSTIVQEFIELVRQNQRFEAVKHSRRYFPKTQLNEICHVMALL 242
8 -5.280[S] COG3334 Uncharacterized conserved protein  ali follow..  14  94............................................................QKILNSINDKTQGRVKEIYSQMKDAAIADVLSQMEDASKIMLSLESR-GVLSKMDPKKASELTLLLKNLDNNAS.......................................................................................................................................................... 171
9 -4.890[S] KOG0212 Uncharacterized conserved protein  ali follow..  10  579..................................LFTAPELYDLRKKLKQSAPKNIFTTL---YTAWCHNSIAVFSLCLLSQNYEHAANLLSVFAEIEFNIDMLIQLDKLVQLIESPVFTYMRLQLLEPE--QSSAFRTLRDRLQCSSTPRTNTILANERLPRSRRDDPYWTDLLERLKAVQLSH....................................................................................................... 743
10 -4.820[MO] KOG4551 GPI-GlcNAc transferase complex, PIG-H component, involved in glycosylphosphatidylinositol anchor biosynthesis  ali follow..  11  97...........................KFVKKESVIILPTFIQLETQYLSGKTVSRFIPIDKILKP----VLVECVTPITCY----LSLFLRGEEQLTLVFKELRPPLKMLVPI----WKALCAAIGTDHQSETIA........................................................................................................................................................ 196

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24