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COG1723
Query: [S] COG1723 Uncharacterized conserved protein, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKSRASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYSQVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPKLFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGFTEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVKLSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILRININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKEQLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQHLast
1 -110.000[S] COG1723 Uncharacterized conserved protein  ali  100  1MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKSRASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYSQVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPKLFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGFTEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVKLSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILRININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKEQLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQH 430
2 -80.200[S] KOG2861 Uncharacterized conserved protein  ali follow..  15  10...KTLGPPVRSILYSIFTSQQKPSSLPPFHFSLRSSSNIPTRCFSNVVAKSNSPIYDFQGFRNLFTERAISSSTTTPVASAQPQQLQNQNQHPAE---------------VDEEISMGLEDEAKLSIPVRAYFFSTSVDLRSLIEQNKQNFIPPTSR----------------MTNYVVLKFGNHSDPTDTTRGRISGSESIYMVVFHYGSIVLFNVREHEVDEYLKVVERHASGLLPEMRKDEYEVRENPNLDTWMEVGRDFIRLQFLN-TDGIRTIGCVLGQSIALDYYGRQVDGMVAEFTEINRQLEITGTFTMKRKKLFQLVGKANVILADVILKLGLFERSDIAWKDAKYGQIWEFLRDEFELTQSFANLDYKLKFVEHNVRFLQEILQNRKSATLEWLIIILISMEIAISFYNMSRASL.... 402
3 -8.150[NU] COG2064 Flp pilus assembly protein TadC  ali follow..  11  112.............................................................................................................................................................................................................................................................................................FYITNVRRGKIDSSLPHAVNMMLGMAKGG---VPLISIFRFVAENREIFGEISREFDKIVTLVEIFGSEKLKVFLENFINVYEGGGDVEYLRAKSEQLLTERETYYTLFFETLQVYAEIYLALFIVAPLFFLIVLVVFQMV.... 265
4 -7.350[TA] KOG1902 Putative signal transduction protein involved in RNA splicing  ali follow..  5.APGKQTLPMREMADLDAVHLGLDENEADIAEELQDFEFNTRSEASESNGGDSSDSEPSISSVSTATSSLAGSSKRKTKKPAKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRTDSGTKKTTSSEASDKVKSKSPDTEDRQPSAKKSRTKIPSNANDSAGHKSDLSEAEDEKPSLPTLESDSESSDSDSGTQHKRNG------------GGGNGRGKPSSKSSTPEKDSVGGGTHSHSQKGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQN--DANLNQAFKEARNV--SVNESGKF------FARMAAPS--------------DIPQVAWVLPP-----KALGGVIELD---ELSFNATLHLHNTWNEGKPVKIGRDGQEIE--------PKIGGELCRLFPE...... 394
5 -7.290[P] COG0598 Mg2+ and Co2+ transporters  ali follow..  12  27.....................................................................................................................................................................................................................VIWDLFNPSSEETRLVEERLGIAIPTRDEMQEIELSDRLYQEDGAEFMTMTATAKLDSDYPAKVPVTFILKGAVMLGLLEAMIDRTADALERAGNDVDQISREVFRKEQIGQKGDLLTVIRESLVSIGRLVAY-----EGSTPRKAAKESRQRILVQRDAASLGDHALFLSNKINFLLDATLGLINLEQNQIIKIFSVAAVVFLPPTLVASIY.... 289
6 -7.160[P] KOG2662 Magnesium transporters: CorA family  ali follow..  12  111..............................................................................................................................................................................................................IITAEEVILMNARDASVVQYQSELCKRLQSNHNLNVKDDLPFEFKALELVLELSCLSL-VLDELATNISTLNLEHVRRLKGRLLTLTQKVQKVCDEIEHLMDDDDDMAEMYLTEKKERAEAHASEELEDNIGEDFSLLSSSSIGENIDQLEMLLEAYFVVVDTLSKLSSLKEYIDDTEDLINIKLGNVQNQ----LIQFQLLLTAATFVAAIFAAVTAVF.... 376
7 -6.410[S] KOG3156 Uncharacterized membrane protein  ali follow..  10  69......................................................................................................................................................................................................................................................................................VSQDLAKREKLTQLSYQQRVDFAKLRDQLLSADRSEFHNI-QNEYESVKNDLEKLRNKLREEITKTNA------KLDLSLEKGRIREESHHDLQIKEIDTKIE---QEVTNMKMQIDSVKTQVMQWLIGVCTGT-LVLAYMRLL........ 206
8 -6.400[NU] COG1459 Type II secretory pathway, component PulF  ali follow..  14  253..............................................................................................................................................................................................................................................................................DDFKLRLPVFGNLIQKSAISSFARTFGLLVSSGVNIIESLEITKGT-ADNAIVEETIENAKNVVISGDQMSSSLATSKVF----------PMVVSMVAIGEETGSLDNMLNKVADFYDREVDEAVESLTAAIEPMMIVFLGGIVGLIVAGMFLPMF.... 398
9 -6.390[DZ] KOG3757 Microtubule assembly protein Doublecortin and related proteins, contain DCX domain  ali follow..  1MPQTSAWQLNDTTARPPPPPPPPGSEAGGSDGASMNGANTLPRVSKRVSAAGKTSNIPRFKRPHLPHSTRPLSAVLTSSSSPVVHRKISPSSSAPSTSSAHRRFSHLPQQHFHHHIHHNQTAVISEETLTTPRASTLNLNQTSVFPTAISQGSMPNSGTNTAEASMTSSVCAMETEGTNGDELAESRDMVSEMQRRCRIGKAKRLRFYRNGQYALQSDRVKSMQPLMEDLMKCDSTALPHGIRHIFTIDGAQRITSVDQFEDGGGYVCSSTDAFKPVDYSRAAEPSWRLTLANRYNRHLETKKLALSVVEPCHENTDFVFPRIIKVIGVKPRRISRHLLNKKTARS---------FDQVLRDLTFVVKLDS--GAI-RKLRPVLSLQDFFRD...................................... 405
10 -5.970[Z] KOG4462 WASP-interacting protein VRP1/WIP, contains WH2 domain  ali follow..  123.APPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPV.......................................................................................................................................................................................................................................................................................................... 253

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.