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COG0117
Query: [H] COG0117 Pyrimidine deaminase, from COG0312

Results of FFAS03 search in COG0312
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTDEQYMKLALALAESARGQTSPNPLVGAVVVKDGQIVGMGAHLKAGEPHAEVHAIRMAGEKAKGATAYVTLEPCSHYGKTPPCADLLIEAGVARVVIATEDPFPKVSGRGIRKLQQAGIEVEVGICKQEALDLNRIFFHFVRLast
1 -91.000[H] COG0117 Pyrimidine deaminase  ali  100  1MTDEQYMKLALALAESARGQTSPNPLVGAVVVKDGQIVGMGAHLKAGEPHAEVHAIRMAGEKAKGATAYVTLEPCSHYGKTPPCADLLIEAGVARVVIATEDPFPKVSGRGIRKLQQAGIEVEVGICKQEALDLNRIFFHFVR 143
2 -48.900[F] KOG3127 Deoxycytidylate deaminase  ali follow..  20  319..ARHCMVQARLLAYRT---EDHKTGVGAVIWAEGKFVGCGYNKFRYIIHAEQNALTFRIKPEERSMIFVTKCPCDE------CVPLIKGAGIKQIYAGDVDVGKKKADISYRFGELEGVSKFTWQLNPSGAYGLEQNEPERR 489
3 -40.900[FJ] COG0590 Cytosine/adenosine deaminases  ali follow..  33  27.QDEQFMRRAIVLAAQA--EAQGEVPVGAVLVRDGEIIAEGWNGSITNAHAEIEVIRKAGKRLLDTTLYVTLEPC------PMCAGALLHSRVKRIVYGAPDLKAGAAGTVMDLFSSQAATVEKGLLEEECRAQLQAFFQRRR 173
4 -35.300[F] KOG1018 Cytosine deaminase FCY1 and related enzymes  ali follow..  22  138.KLIDLGYTMSKPAKLALEALE--P-VGCVFLEDGKVIASGRNRT-ATRHAEMEAIDQLVGQWQKCVLYVTCEPC------IMCASALSFLGIKEVYYGCPNDKFGGCGSILSLHLGSEYKCRGGIMAEEAVSLFKCFYEQGN 296
5 -34.600[F] COG2131 Deoxycytidylate deaminase  ali follow..  27  7..DQYFMAQSHLLALRS---TCTRLMVGATIVRDKRIIAGGYN---GSIHAEVNALLQCGVPTEGAEIYVTHFPCVN------CTKAIIQSGIKKVYYATDYKNSPYA---EELFRDAGVDVEVELEEMILDRHNEEKLTFTA 158
6 -13.700[A] KOG2771 Subunit of tRNA-specific adenosine-34 deaminase  ali follow..  16  157.AQRTFHKRIGQLLVRLSRDVNANRPVGICV-RQPSIVSIAGTGEVCRPHCCMMLVDFVARSCTGYDIYLLQEPCL-------CSMALVHSRAKRVFFV-KNSENGALATRFQLHSVRELEVFQFTTKEDED........... 358
7 -6.800[T] KOG2210 Oxysterol-binding protein  ali follow..  19  435....KWYLSAFHAGRKGSVAKKPNP-----------ILGEIFQCHWTLPNDTEENTELVSEVSKNSVTFVA-EQVSHH---PPISAFYAECFNKKIQFAHIWTKSKFLGMSIGV-------HNIGQGCVSCLDYDEHY..... 553
8 -6.450[F] COG0295 Cytidine deaminase  ali follow..  16  1MNRQELITEALK-ARDMAYAPYSKFQVGAALLTKDGKVYRGCNIENAA--AERTALFKAVSEGDTEFQMLAVSPCG-------CRQVISELCTKDVIVVLTNLQGQIKEMTVEEL............................ 120
9 -5.790[R] COG1402 Uncharacterized protein, putative amidase  ali follow..  19  24............................ISVLPLGAHEQHGPHLPFETDTLIAAGIVSRLAAVLPAHLPVSFLPVEPVGYSIGIAEAEYEKGVRKFVM--------LNAHG................................ 119
10 -5.620[O] KOG1651 Glutathione peroxidase  ali follow..  10  31................................QGKVLLIVNVASKCGFTETNYTQLTELYRKYKDQDFEILAFPCNQFLYQEPGTSQEAHEKAEYPVFQKVR----VNGQNAAPIYKFLKASKPTFLGSRIKWNFTKFL.... 139

FFAS is supported by the NIH grant R01-GM087218-01
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Locations of visitors to this page
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.