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Query: 1sep_A mol:protein length:261 SEPIAPTERIN REDUCTASE, from PDB0516

Results of FFAS03 search in JCSG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEADGLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKVVLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNYWALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQVLAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLGLLQKDTFQSGAHVDFYDLast
1 -52.200MA16054B NP_077284.2 400347 Cloned-2009-02-26  ali follow..  19  1MARPGMERRLALVTGASGGIGAAVARALVQ---QGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRS----QHSGVDICINNAGLA---RPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRPLSVTHFYSATKYAVTALTEGLRQEQTHIRATCISPGVVETQFAFKLHDKDP-----EKAAATYEQMKCLKPEDVAEAVIYVLSTP-----AHIQIGD 250
2 -51.600MA16054A NP_808232.2 399927 Purified-2009-03-14  ali follow..  19  4AGMERWRDRLALVTGASGGIGAAVARALVQ---QGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAVRS----QHSGVDICINNAGMA---RPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNIDDGHIININSMCGHRPQSVIHFYSATKYAVTALTEGLRQEQTHIRATCISPGLVETQFAFKLHDKDP-----GEAAATYEHIKCLRPEDVAEAVIYVLSTP-----PHVQVGD 250
3 -45.300MA0019I NP_031647.1 399939 Purified-2009-03-14  ali follow..  23  4....NFSGLRALVTGAGKGIGRDTVKALHA---SGAKVVAVTRTNSDLVSLAKE------CPGIEPVCVDLGDWDATEKALGGI--------GPVDLLVNNAAL---VIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINR-GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEPHKIRVNSVNPTVVLTDMGKKVSA---DPEFARKLKERHPLRKFAEVEDVVNSILFLLSDSASTSGGGILV.. 237
4 -45.200MA0019W NP_057370.1 400310 Cloned-2009-02-26  ali follow..  23  4....FLAGRRVLVTGAGKGIGRGTVQALHA---TGARVVAVSRTQADLDSLVRE------CPGIEPVCVDLGDWEATERALGSV--------GPVDLLVNNAAV---ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIAR-GVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALEPHKIRVNAVNPTVVMTSMGQATWS---DPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDSGMTTGSTLPV.. 237
5 -44.500MA0019AB NP_878912.1 400348 Purified-2009-05-08  ali follow..  22  33....VLANRVAVVTGSTSGIGFAIARRLAR---DGAHVVISSRKQQNVDRAMAKLQGE--GLSVAGIVCHVGKAEDREQLVAKALE----HCGGVDFLVCSAGV----LVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRG---AVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALEPKDIRVNCVVPGIIKTDFSKVVRIGFMGMSLGRTSRNIISCRGLGSQRTVQESCPSCALQMATSTGRTLRW.. 277
6 -44.000TM0019 TM0019 281900 Crystal|NMR-2004-03-31  ali follow..  22  2.....LEGKVAVVTGGGQGIGAAIAQLFAE---NGMKVVIAEIDEEAGVEREEMLRER--GLDVTFVKTDVADENSVKNMVRKTVE----IYGGVDVLVNNAAVMSV---KSIFERPLEEWERVIRVNLTGPYICSRYCAEEMIKRGG--GVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLAVSRYHIRVVSISPGWIETSEWKKKSLRKKP-DLRPIDHEQHPAGRVGNPLDIAHLCVFLADDEGFITGTNFIV.. 244
7 -44.000MA0019AT NP_001033027.1 400158 Purified-2009-03-13  ali follow..  20  30....PLSNKVALVTASTDGIGFAIARRLAE---DGAHVVVSSRKQQNVDRAVATLQGE--GLSVTGIVCHVGKAEDREKLITTALK----RHRGIDILVSNAAVNPFFG--NLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKRGG--GSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAEPKNIRVNCLAPGLIKTRFSSVLWE---EKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDSYINGETVVV.. 271
8 -43.800MA0019Z NP_066284.2 400328 Purified-2009-05-08  ali follow..  21  29....PLANKVALVTASTDGIGFAIARRLAQ---DGAHVVVSSRKQQNVDQAVATLQGE--GLSVTGTVCHVGKAEDRERLVATAVK----LHGGIDILVSNAAVNPFFG--SIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIEPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGE---PEDCAGIVSFLCSEDSYITGETVVV.. 270
9 -43.700MA0019AN NP_000851.2 400410 Cloned-2008-02-06  ali follow..  20  2....HVNGKVALVTGAAQGIGRAFAEALLL---KGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVD----HFGRLDILVNNAGVNNE-----------KNWEKTLQINLVSVISGTYLGLDYMKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALANSGVRLNAICPGFVNTAILESIEKEGQYIEYKDHIKDMIKYYGILDPPLIANGLITLI-EDDALNGAIMKI.. 245
10 -43.500MA16027D NP_079798.1 399999 Purified-2009-03-27  ali follow..  21  2.........VVWVTGASSGIGEELAFQLSKL---GVSLVLSARRAQELERVKRRCLENGKEKDILVLPLDLTDTSSHEAATKAVLQ----EFGKIDILVNNGGR----QRSLVLETNLDVFKELINLNYIGTVSLTKCVLPHMIERK--QGKIVTVNSIAGIASVSLSSGYCASKHALRGFFNALHSEYPGITFCNVYPGPVQSDIVKNAFTEEVTKSMRNN----IDQSYKMPTSRCVRLMLISMANDL........... 231
11 -42.800MA16027G NP_057113.1 400391 Purified-2009-03-27  ali follow..  20  45..EWELTDMVVWVTGASSGIGEELAYQLSKL---GVSLVLSARRVHELERVKRRCLENGKEKDILVLPLDLTDTGSHEAATKAVLQ----EFGRIDILVNNGGM----QRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERK--QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTEYPGIIVSNICPGPVQSNIVENSLAGEVTKTIGNN----GDQSHKMTTSRCVRLMLISMANDL........... 281
12 -42.600BA0019B BAIA2 423431 Purified-2010-09-20  ali follow..  18  4.....VQDKIVIITGGTSGIGLCAAKIFMD---NGATVSIFGKTQEEVDAAKAELKETHPDKEVLGFAPDLTNRDEVMAAVGAVAE----KYGRLDVMINNAGVTSS---NVFSRVSPEEFTYLMDINVTGVFHGAWAAYHCLKGEKK---IIINTASVTGIHGSLSGVGYPTSKSAVVGFTQALGRERKNIRVVGVAPGVVNTPMVGNIPD-----EILDGYLSSFPMKRMLEPEEIANTYLFLASDASGITATTVSV.. 242
13 -42.600MA0019X NP_932349.2 400312 Purified-2009-05-08  ali follow..  22  23TRRDPLTNKVALVTASTDGIGFAIARRLAQ---DRAHVVVSSRKQQNVDQAVATLQGE--GLSVTGTVCHVGKAEDRERLVAMAVK----LHGGIDILVSNAAV----FFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIEPRNIRVNCLHLDLSRLASAGCSGWTRKKRKA.......................................... 230
14 -42.300MA16027F NP_861420.1 400375 Cloned-2009-02-26  ali follow..  21  27FRPEMLQGKKVIVTGASKGIGREMAYHLAKM---GAHVVVTARSKETLQKVVSHCLELGAA-SAHYIAGTMEDMTFAEQFVAQAGK----LMGGLDMLILNHIT----TSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNG---SIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKERVNVSITLCVLGLIDTETAMKAVSGIVHM-------------QAAPKEECALEIIKGGALRQ........... 253
15 -42.300MA16027A NP_663403.1 399816 Purified-2009-03-14  ali follow..  20  45RSKAYLRNAVVVVTGATSGLGRECAKVFHA---AGAKLVLCGRNVKALEELSRELAGSSQTHQPFVVTFDLADPGTIAAAAAEILQ----CFGYVDVLINNAGI----YRGTISDTIVDVDRKVMEINYFGPVALTKALLPSMVERK--QGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEEANIKVTVISPGYIHTNLSVNAVTADGSRYGALD----KNTAQGRSAAEVAQDVFDAVGKKK........... 282
16 -42.000BA0019D BAIA1 424701 Crystal|NMR-2012-07-06  ali follow..  18  4.....VQDKITIITGGTRGIGFAAAKLFIE---NGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMAAVGTVAQ----KYGRLDVMINNAGITMN---SVFSRVSEEDFKNIMDINVNGVFNGAWSAYQCMKDAKQ--GVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGRERKNIRVVGVAPGVVDTDMTKGLPP-----EILEDYLKTLPMKRMLKPEEIANVYLFLASDASGITATTISV.. 243
17 -42.000BA0019C BAIA2 423436 Diffraction|HSQC-2012-07-20  ali follow..  20  4.....VQDKITVITGGTRGIGFTAAKIFIE---NGAKVSIFGETKEEVDTALAELKELYPEEEVLGFAPDLTSRDAVMAAVRAVAE----KYGRLDVMINNAGITMN---TVFSRVTEEAFKHMMDINVIGVFNGAWAAYQCMKGAQQ--GVIINTASVTGIYGSLSGIGYPASKAGVIGLTQGLGRERKNIRVVGVAPGVVDTDMTKGLPP-----EILEDYLKSFPMKRMLKAEEIANVYLFLASDASGITATTVSV.. 243
18 -41.800BA0019A BAIA2 420767 PDB-2013-01-16  ali follow..  19  4.....VQDKVTIITGGTRGIGFAAAKIFID---NGAKVSIFGETQEEVDTALAQLKELYPEEEVLGFAPDLTSRDAVMAAVGQVAQ----KYGRLDVMINNAGITSN---NVFSRVSEEEFKHIMDINVTGVFNGAWCAYQCMKDAKK--GVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGRERKNIRVVGVAPGVVNTDMTNGNPP-----EIMEGYLKALPMKRMLEPEEIANVYLFLASDASGITATTVSV.. 243
19 -41.600MA16027B NP_056325.2 399871 Purified-2009-03-14  ali follow..  20  45RGKAYLRNAVVVITGATSGLGKECAKVFYA---AGAKLVLCGRNGGALEELIRELTASHQTHKPYLVTFDLTDSGAIVAAAAEILQ----CFGYVDILVNNAGI----YRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRR--QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEQYEIEVTVISPGYIHTNLSVNAITADGSRYGVMD----TTTAQGRSPVEVAQDVLAAVGKKK........... 284
20 -40.800MA0019AQ NP_081484.1 400099 Purified-2009-03-13  ali follow..  22  3....RLDGKVIVLTAAAQGIGRASALAFAR---EGAKVIATDINESKLQELES-------YRGIQTRVLDVTKKRQIDQFASEI--------ERIDVLFNVAGF---VHHGTILDCEEKDWDFSMNLNVRSMFLMIKAFLPKMLAQKS--GNIINMSSVASIKGVENRCVYSATKAAVIGLTKSVAADQQGIRCNCVCPGTVDTPLQERIQARDNPKEALKTFLNRQKTGRFASAEEVALLCVYLASDESYVTGNPV.... 237
21 -40.600TM0325 TM0325 282200 Crystal|NMR-2003-02-19  ali follow..  18  2....NFQGKVVLITGAGSGIGKKAAVMFAE---RGAKVAINDISEEKGKETVELIKSM--GGEAAFIFGDVAKD------AEQIVKKTVETFGRLDILVNNAGIVPY---GNIEETSEEDFDKTMAVNVKGPFLLSKYAVEQMKKQGG--GVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDDYGIRVNAVCPGTTQSEGMARVKASPNPEELLKKMTSRIPMKRLGKEEEIAFAILFAACDEGFMTGSIINI.. 244
22 -40.500MA0019AW NP_038571.2 400480 Purified-2009-05-08  ali follow..  24  3.SQLRLRSALALVTGAGSGIGRAISVRLAA---EGAAVAACDLDGAAAQDTVRLLGSPAPRGKHAAFQADVSQGPAARRLLEEVQACFSR----PSVVVSCAGITRD---EFLLHMSEEDWDRVIAVNLKGTFLVTQAAAQALVSSGG-RGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARERHGIRCNSVLPGFIATPMTQKMPE-----KVKDKVTAMIPLGHMGDPEDVADVVAFLASEDGYITGASVEV.. 253
23 -40.500MA0019Q NP_000404.1 400282 Selected-2008-12-22  ali follow..  19  1.....MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALAPPGSLETLQLDVRDSKSVAAARERVTE------GRVDVLVCNAGL----LLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRG--SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVL--GVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLNPEEVAEVFLTALRAPK........... 249
24 -40.300TM0297 TM0297 282173 Purified-2001-03-14  ali follow..  19  9....SLKRKVALVTGGGQGIGKAIAQALAA---AGAAVLIMDINEETARRTVEEIKEK--GGEADFYVGDVTKEEDCFGAVKKALD----RWGKLDIGVNNAGI---GDWCEAENYPVEKWKKVIDVNLVGVFLSAKAEFHAMKERKY--GKIINIASMSGHNKPQKQTAYNASKAGVIHLTRSLAAEPYGIRVNSISPGYIRTPLIESPNVK----DLVPLWLDMIPLGRLGEVDDLIGAAIFLASPSDYMTGHDLVI.. 250
25 -40.300MA0019BE NP_064524.3 400257 Cloned-2009-03-24  ali follow..  21  3....RLDGKVIILTAAAQGIGQAAALAFAR---EGAKVIATDINESKLQELEKY-------PGIQTRVLDVTKKKQIDQFANEV--------ERLDVLFNVAGF---VHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKS--GNIINMSSVASVKGVVNRCVYSTTKAAVIGLTKSVAADQQGIRCNCVCPGTVDTPLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESYVTGNPV.... 237
26 -40.000MA0019C NP_055049.1 399864 Purified-2009-03-14  ali follow..  22  6..QNRLRSALALVTGAGSGIGRAVSVRLAG---EGATVAACDLDRAAAQETVRLLGGPGPRGNHAAFQADVSEARAARCLLEQVQACFSR----PSVVVSCAGITQD---EFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGC-RGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARERHGIRCNSVLPGFIATPMTQKVPQ-----KVVDKITEMIPMGHLGDPEDVADVVAFLASEDGYITGTSVEV.. 255
27 -39.900MJ10696C YP_957804.1 403192 Purified-2009-11-23  ali follow..  18  3..........TVIAGVSGAIGGALARRYLSS-YPDRSLIGLCRRPETAPDDLRN------HSGVRLMAWDAEDEQRLDVAEFKAVLE---ASGPVYTVIYAGGLLHD-PEKRLEDIDGRSMMRSYQVNCLGFVSLMQRLAPALRGKHFKRIAAVSAKVGSSDNQLGGWYAYRASKAALNMVVKNLSIEYAPLACVSLHPGTTLSSLSQ--------------FQQSLEQLTVHEPEQTASNLFSVLESDARDNGRFISW.. 237
28 -39.300MJ16363A YP_775298.1 402450 Purified-2009-09-04  ali follow..  18  4.TVSNASTPSILLIAASRGLGLAMAEHF---LNKGWHVTGTVRAGSGRTKLHE---AERFGERLEIDTLDICAPDQLAALRARL------SGRRFDMLFVNAGTTND-PNETIGEVTTDEFVRVMITNALAPMRVIEALHDLVPEG----GLIGAMSSGQGSNVSGMREVYRGSKAALNQFMRSFAARATPRAMVLMAPGWVRTEL---------------------GPDARLTIDESVPSLVNVLIGKQRRAG....... 225
29 -39.200MA16027C NP_002026.1 400344 Cloned-2009-02-26  ali follow..  17  29....ALPGAHVVVTGGSSGIGKCIAIECYK---QGAFITLVARNEDKLLQAKKEIEMHNDKQVVLCISVDVSQD---YNQVENVIKQAQEKLGPVDMLVNCAGMAVS---GKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERR--VGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEPYNVYITVAYPPDTDTPGFAEENRTKPLET-----RLISETTSVCKPEQVAKQIVKDAIQGNF.......... 263
30 -39.100MA16027E NP_081810.1 400040 Purified-2009-03-27  ali follow..  18  29....ALPGAHVVVTGGSSGIGKCIAIECYK---QGAFITLVARNEDKLLQAKKDIEKHNDKQVVLCISVDVSQD---YNQVENVIKQAQEKLGPVDMLVNCAGTSMS---GKFEELEVSSFEKLMSINYLGSVYPSRAVITTMKERR--VGRIVFVSSQAGQLGLFGFTAYSSSKFAIRGLAEALQME--NVYVTVAYPPDTDTPGLAEENKTKPLET-----RLISETTAICKPEQVAKQIVKDAIQGNF.......... 263
31 -38.900MA0019A 14318639 399823 Purified-2009-03-27  ali follow..  22  3........KVCAVFGGSRGIGRAVAQLMAQ---KGYRLAIVSRNLEVAKVTAGEL-----GGNHLAFRCDVAKEQDVQSTFQEMEK----HLGPVNFLVNAAGINRG---SLLVRTKTEDMISQLHTNLLGSMLTCKAAMKTMIQQGG---SIVNVGSIIGLKGNVGQSAYSATKGGLVGFSRSLAKERKKIRVNVVAPGFIRTDMTRHLKE--------EHFKKNIPLGRFGETLEVAHAVV-FLLESPYITGHVLIV.. 228
32 -38.700TM1724 TM1724 283580 Purified-2001-12-11  ali follow..  21  3.....LEGKVCLITGAASGIGKATTLLFAQ---EGATVIAGDISKENLDSLVKEAEGL--PGKVDPYVLNVTDRDQIKEVVEKVVQ----KYGRIDVLVNNAGITRD---ALLVRMKEEDWDAVINVNLKGVFNVTQMVVPYMIKQRN--GSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKEGRNIRVNAVAPGFIETPMTEKLPE-----KARETALSRIPLGRFGKPEEVAQVILFLASDESYVTGQVIGI.. 240
33 -38.200MJ10696B YP_156827.1 403089 Purified-2009-10-23  ali follow..  17  3..........MVVLGAGGGLGRAITLELSKQ-YPDERIFALSRQPEV---------PETDSSDVTYCRIEDYDEKALGAWVSEFKN----NGEQLSGVVSTIGMLHD-PEKKLTDITADNLNKLFSVNAVKPMLALKAFLPILDRKKTRFWVQLSAKVGSEDNYLGGWYAYRSSKAGLNMLLKTASIEHKNLIVAAIHPGTTDTRLSE--------------FQERISTDKLYSPELSAERIVAVVKNKPENTGALWHW.. 233
34 -38.200TM0441 TM0441 282314 PDB-2004-07-14  ali follow..  21  6....DLRGRVALVTGGSRGLGFGIAQGLAE---AGCSVVVASRNLEEASEAAQKL-TEKYGVETMAFRCDVSNYEEVKKLLEAVKE----KFGKLDTVVNAAGI---NRRHPAEEFPLDEFRQVIEVNLFGTYYVCREAFSLLRESDN--PSIINIGSLTVEETMPNISAYAASKGGVASLTKALAKERYGIRVNVIAPGWYRTKMTEAVFS---DPEKLDYMLKRIPLGRTGVPEDLKGVAVFLASEAKYVTGQIIFV.. 248
35 -37.500MA0019AJ NP_116172.2 400081 Purified-2009-03-27  ali follow..  24  3........KVCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNLEGAKAAAGDL-----GGDHLAFSCDVAKEHDVQNTFEELEK----HLGRVNFLVNAAGINRD---GLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKERKKIRVNVVAPGFVHTDMTKDLKE--------EHLKKNIPLGRFGETIEVAHAVV-FLLESPYITGHVLVV.. 229
36 -37.300NS10696G YP_001052213.1 380878 Crystal|NMR-2007-12-14  ali follow..  22  3..........VLIVGGSGGIGQAMVKQVQET-YPDATVHATYRHHLPNDRQN----------NIQWHALDVTNEAEIKQLSEQL--------TELDWLINCVGILHT-PEKSLQSLDIDFFQHNLTLNTLPSVMLAKHFCHALKQSDSARFAVISAKVGSTDNRLGGWYSYRASKAALNMFLKTLAIEMKHCVVLSLHPGTTDTPLS-------------QPFQQSVPKGKLFTPEYVANCLLPIIANTPAQTGCFFAY.. 228
37 -37.200MA0019V NP_060911.2 400308 Cloned-2009-02-26  ali follow..  19  11LAPGLLQGQVAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANTKQARVIPIQCNIRNEEEVNNLVKSTLD----TFGKINFLVNNGGG------SPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHG--GSIVNIIV-PTKAGFPLAVHSGAARAGVYNLTKSLALECSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKI---KRIGVPEEVSSVVCFLLSPASFITGQSVDV.. 261
38 -37.000MA0019H NP_076012.2 399938 Selected-2008-12-22  ali follow..  18  11LAAGLLKNQVAVVTGGGTGIGKAVSRELLHL---GCNVVIASRKLDRLTAAVDELRASSSSAEVSAIQCNIRKEEEVSNLVKSTLA----KYGKINFLVNNGGG------APVEDITAKGWHAVIETNLTGTFYMCKEVYNSWMREHG--GSIVNIIVLLN-NGFPTAAHTGAAREGVYNLTKSMALASSGVRINCVAPGTIYSQTAVD-NYGEMGQTLFEMAFDSIPAKRLGVPEEISPLVCFLLSPASYITGQLINV.. 261
39 -35.900MA0019BC NP_742034.1 400213 Selected-2008-12-22  ali follow..  17  30.KEKSVAGQVCLITGAGSGLGRLFALEFARR---RALLVLWDINTQSNEETAGMVRHPHCNLQVFTYTCDVGKRENVYLTAERVRK----EVGEVSVLVNNAGV---VSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEIN--HGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLP----------PLKPDYCVKQAMKAILTDQ........... 284
40 -35.800MA3792B NP_000188.1 400036 Purified-2009-03-27  ali follow..  21  48.......GQWAVITGAGDGIGKAYSFELAK---RGLNVVLISRTLEKLEAIATEIERTT-GRSVKIIQADFTKDDIYEHIKEKL------AGLEIGILVNNVGMLPNLLP-SHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQ--KGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEAKEVIIQVLTPYAVSTAMTKYLNTN------------------TKTADEFVKESLNYVTIGGETCG....... 267
41 -35.700MA0019AD 18043883 400008 Purified-2009-03-27  ali follow..  15  30.RRKSVTGQTVLITGAGHGIGRLTAYEFAKQ---KSRLVLWDINKRGVEETADKCRKL--GAVVHVFVVDCSNRAEIYNSVDQVKR----EVGDVEIVVNNAGA---IYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRN--SGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAEKTGIKTSCLCPVFVNTGFTKNPSTR-----------------PVLEPEEVARSLINGILTNK........... 254
42 -35.700MA0019S NP_835236.1 400288 Purified-2009-05-08  ali follow..  15  30.RRKSVAGEIVLITGAGHGIGRQTTYEFAKR---QSILVLWDINKRGVEETAAECRKL--GVTAHAYVVDCSNREEIYRSLNQVKK----EVGDVTIVVNNAGT---VYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERN--HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSEKTGIKTSCLCPVFVNTGFTKNPSTR-----------------PVLETDEVVRSLIDGILTNK........... 254
43 -35.200MA0019AO NP_057329.2 400423 Cloned-2008-02-06  ali follow..  16  30.RRKSVTGEIVLITGAGHGIGRLTAYEFAKL---KSKLVLWDINKHGLEETAAKCKGL--GAKVHTFVVDCSNREDIYSSAKKVKA----EIGDVSILVNNAGV---VYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNN--HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDEITGVKTTCLCPNFVNTGFIKNPSTS-----------------PTLEPEEVVNRLMHGILTEQ........... 254
44 -35.100MA0019P NP_444492.1 399997 Purified-2009-03-27  ali follow..  15  30.KKKSVAGEIVLITGAGHGIGRLTAYEFAKL---NTKLVLWDINKNGIEETAAKCRKL--GAQAHPFVVDCSQREEIYSAAKKVKE----EVGDVSILVNNAGV---VYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNN--HGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDERTGVRTSCLCPNFINTGFIKNPSTN-----------------PTLEPEEVVEHLMHGILTEK........... 254
45 -35.100MA3792A NP_057226.1 400351 Selected-2008-12-22  ali follow..  24  50.......GEWAVVTGSTDGIGKSYAEELAK---HGMKVVLISRSKDKLDQVSSEIKEKF-KVETRTIAVDFASEDIYDKIKTGL------AGLEIGILVNNVGMSYEYPEYFLDVPDLDNIKKMININILSVCKMTQLVLPGMVERS--KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEESKGVFVQSVLPYFVATKLAKIRKPT................................................ 246
46 -35.100MA16118A NP_057455.1 400208 Cloned-2009-02-26  ali follow..  18  2.......RKVVLITGASSGIGLALCKRLLAE-DDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVDVSNLQSVFRASKELKQ----RFQRLDCIYLNAGIMAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDN-PSQLIWTSSRSARQHSKGKEPYSSSKYATDLLSVALNFNQQGLYSNVACPGTALTNLTYGI................................................... 234
47 -34.800MA0019AX NP_871789.1 400495 Purified-2009-05-08  ali follow..  20  34.PRKNVAGEIVLITGAGSGLGRLLALQFARL---GAVLVLWDVNKEANDETHQLAREAG-AARVHAYTCDCSRREEVYRVADQVKK----EVGDVSILINNAGI---VTGRNFLDCPDDLMEKSFDVNFKAHLWMYKAFLPAMIANN--HGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFIEQWGIKTTIVCPFFIKTGMFEGCTTKCPTL-------------PILDPEYAVRKIIDAILQEQ........... 262
48 -34.700MA3792D NP_780394.1 400525 Selected-2008-12-22  ali follow..  14  67.......GRWAVISGATDGIGKAYAEELAS---HGLNVILISQEEEKLQAAAKHIADTY-RVETLVLVADFSRGREIYAPIREALR-----DRDIGILVNDVGAFYPYPQ-YFSQVPEDTLWDIVNVNIAAASLMVHIVLPGMVERK--KGAIVTVSSGSCCKPTPQLAAFSASKAYLDHFSRALQYESKGIFVQSLIPFYVTSSGASFLHRCPWLAPSPRVYAQ.................................... 277
49 -34.600MA0019AA NP_004744.2 400346 Purified-2009-05-08  ali follow..  22  32.KLRDLSRENVLITGGGRGIGRQLAREFAER--GARKIVLWGRTEKCLKETTEEIRQM--GTECHYFICDVGNREEVYQTAKAVRE----KVGDITILVNNAAV---VHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQ--NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGCPGVSATTVLPFHTSTEMFQGMRVRFPNL-------------PPLKPETVARRTVEAVQLNQ........... 258
50 -34.600MA0019F NP_780581.1 400535 Cloned-2009-02-26  ali follow..  18  32.SKATIPGKTVIVTGANTGIGKQTALELAK---RGGNVILACRDMEKCEVAAKDIRGETLNPRVRAERLDLASLKSIREFARKVIK----EEERVDILVNNAAVMR-------HWTTEDGFEMQFGVNYLGHFLLTNLLLDKLKAS--APSRIINLSSLAQMKKYDTKAAYCQSKLAVVLFTKELSLQGSGVTVNALHPGVARTELGRHT................................................... 241
51 -34.600MA3792C NP_113651.3 400501 Cloned-2009-03-24  ali follow..  17  67.......GRWAVVSGATDGIGKAYAEELAS---RGLNIILISRNEEKLQVVAKDIADTY-KVETDIIVADFSSGREIYLPIREALK-----DKDVGILVNNVGVFYPYPQ-YFTQLSEDKLWDIINVNIAAASLMVHVVLPGMVERK--KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYESKGIFVQSLIPFYVATSMTAFLHRCSWLVPSPKVYAH.................................... 277
52 -34.500MA0019G 15488817 399937 Purified-2009-03-14  ali follow..  22  32.KLRDLSRESVLITGGGRGIGRHLAREFAER--GARKIVLWGRTEKCLKETTEEIRQM--GTECHYFICDVGNREEVYQMAKAVRE----KVGDITILVNNAAV---VHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQ--NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGCPGVSATTVLPFHTSTEMFQGMRVRFPNL-------------PPLKPETVARRTVDAVQQNQ........... 258
53 -34.500MA0019BB NP_620419.2 400206 Purified-2009-05-08  ali follow..  20  34.PRKNVAGEIVLITGAGSGLGRLLALQFARL---GSVLVLWDINKEGNEETCKMAREAG-ATRVHAYTCDCSQKEGVYRVADQVKK----EVGDVSILINNAGI---VTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIAND--HGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVEQKGIKTTIVCPFFIKTGMFEGCTTGCPSL-------------PILEPKYAVEKIVEAILQEK........... 262
54 -34.500MA0019N NP_067532.2 399974 Purified-2009-03-27  ali follow..  20  32.SNVQLPGKVAIVTGANTGIGKETAKDLAQ---RGARVYLACRDVDKGELAAREIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLA----EEKHLHLLINNAGVMM-------YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKES--APSRIVNLSSLGGEKFYSAGLAYCHSKLANILFTKELALKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFVF--------IKTPQEGAQTSLYCALTEGLESGSHFS... 282
55 -34.500MA0019AG NP_057110.2 400022 Purified-2009-03-27  ali follow..  21  35.STVQLPGKVVVVTGANTGIGKETAKELAQ---RGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLA----EEKHLHVLINNAGVMM-------YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKES--APSRIVNVSSLAGEKFYNAGLAYCHSKLANILFTQELALKGSGVTTYSVHPGTVQSELVRHSSFMRWMWWLFSFF--------IKTPQQGAQTSLHCALTEGLESGNHFS... 285
56 -34.400MA0019AH NP_689656.1 400026 Purified-2009-03-27  ali follow..  20  33.TNVQLPGKVVVITGANTGIGKETARELAS---RGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLA----EEKQLHILINNAGVMM-------YSKTADGFETHLGVNHLGHFLLTYLLLEQLKVS--APARVVNVSSVASEKRYSRGFAYCHSKLANVLFTRELALQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPF--------VKTAREGAQTSLHCALAEGLESGKYFS... 283
57 -34.300MA0019M 17390614 399972 Purified-2009-03-27  ali follow..  24  22QVVDHLQDKYVFITGCGSGFGNLLARQLDRR---GMRVLAACRKEEGAEELRRKTSE-----RLETVILDVTKTESIVAATQWVKERVGNRGL---GLVNNAGISVPSG--PNEWMKKQDFASVLDVNLLGLIEVTLSMLPLVRKARG---RVVNVSSILGRVSLGGSGGYCISKYGIEAFSDSLRRE--GVKVAIIEPGFFLTGMASS.................................................... 217
58 -33.800MA0019AM NP_065956.1 400394 Selected-2008-12-22  ali follow..  18  37.DPGLMHGKTVLITGANSGLGRATAAELLR---LGARVIMGCRDRARAEEAAGQLRRELRQAELIVRELDLASLRSVRAFCQEMLQ----EEPRLDVLINNAGIFQ-------YMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSS--APSRIVVVSSKLSEQSYNKSFCYSRSKLANILFTRELALEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWA-----FKTPVEGAQTSIYLASSPEVESGRYFG... 304
59 -33.400MA0019O 18043331 399990 Purified-2009-03-27  ali follow..  19  38.DPGLMHGKTVLITGANSGLGRATAAELLR---LGARVIMGCRDRARAEEAAGQLRQEGTDGQLVVKELDLASLRSVRAFCQELLQ----EEPRLDVLINNAGVFH-------YTKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSS--APSRIVVVSSKLSEQSYNKSFCYSRSKLANILFTRELALEGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWA-----FKTPLEGAQTSIYLACSPDVESGRYFG... 302
60 -33.300MA0019AI NP_660160.1 400065 Selected-2008-12-22  ali follow..  22  37.VFPPRPDRVAIVTGGTDGIGYSTAKHLARL---GMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDLASMTSIRQFVQKFKM----KKIPLHVLINNAGVM--------QRKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESPGHSARVVTVSSATSSACYSPHAAYAQSKLALVLFTRLLAAEGSHVTANVVDPGVVNTDLYKHV................................................... 251
61 -33.200MA0019BD NP_059501.1 400248 Cloned-2009-02-26  ali follow..  25  22QVVSHLQDKYVFITGCDSGFGNLLARQLDRR---GMRVLAACLTEKGAEQLRNKTSD-----RLETVILDVTKTESIVAATQWVKERVGNRGL---GLVNNAGICVF---AINEWLKKEDFANILDVNLLGMIEVTLSMLPLVRKARG---RVVNISSSMGRVSLCG-GGYCISKYGVEAFSDSLRRE--GVKVAIIEPGGFRTNVSN..................................................... 214
62 -33.100MA0019AV O54909 400476 Cloned-2009-03-24  ali follow..  23  22QVVSHLQDKYVFITGCDSGFGTLLARQLDRR---GMRVLAACLTEKGAEELRNK-----TSDRLETVILDVTKTESIVTATQWVKEHVGNRGL---GLVNNAGISTPSG--PNEWMKKQDFAHVLDVNLLGMIEVTLSMLPLVRKARG---RVVNVSSVMGRVSLFG-GGYCISKYGVEAFSDSLRRE--GVKVAIIEPGFFLTGVTSS.................................................... 216
63 -33.000TM1169 TM1169 283034 PDB-2003-09-17  ali follow..  18  4....GIRDKGVLVLAASRGIGRAVADVLSQ---EGAEVTICARNEELLKRSGHRY-----------VVCDLRKD----------LDLLFEKVKEVDILVLNAG-----KAGFFDELTNEDFKEAIDSLFLNMIKIVRNYLPAMKEKG---GRIVAITSFSVISPIENLYTSNSARMALTGFLKTLSFEPYGITVNCVAPGWTETERVKELLSEEKKKQVESQI----PMRRMAKPEEIASVVAFLCSEASYLTGQTI.... 226
64 -32.800MA0019AS NP_005762.2 400138 Purified-2009-03-27  ali follow..  22  22LKIEDITDKYIFITGCDSGFGNLAARTFDKK---GFHVIAACLTESGSTALKAETSE-----RLRTVLLDVTDPENVKRTAQWVKNQVGEKGL---GLINNAGVPGVLA--PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG---RVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRD--GVHVSCIEPGLFKTNLADP.................................................... 216
65 -32.600MA0019AP NP_003716.2 400428 Purified-2009-05-08  ali follow..  23  22QVVSHLQDKYVFITGCDSGFGNLLARQLDAR---GLRVLAACLTEKGAEQLRGQTSD-----RLETVTLDVTKMESIAAATQWVKEHVGDRGL---GLVNNAGILTPIT--LCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARG---RIVNVSSILGRVAFFV-GGYCVSKYGVEAFSDILRRE--GVKISIVEPGYFRTGMTNM.................................................... 216
66 -32.400MA0019AE 18256860 400009 Purified-2009-03-27  ali follow..  23  22QVVSHLQDKYVFITGCDSGFGNLLARQLDRR---GMRVLAACLTEKGAEELRNKTSD-----RLETVILDVTKTESIVAATQWVKERVGDRGL---GLVNNAGVLQPFA--YIEWYRPEDYMPIFQVNLIGLTQVTISMLFLVKKARG---RIVNVSSALGRVALFG-GFYSCSKYGVEAFSDVLRHE--GVKVSIIEPGSFKTEMTDA.................................................... 216
67 -32.300MA0019J NP_002896.2 399953 Purified-2009-03-14  ali follow..  24  25....PASNALVFITGCDSGFGRLLALQLDQR---GFRVLASCLTPSGAEDLQRVASS-----RLHTTLLDITDPQSVQQAAKWVEMHVKEAGL----LVNNAGVAGIIG--PTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARG---RVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRD--GIRVSIVEPGFFRTPVTNL.................................................... 215
68 -32.300MA0019AC NP_598767.1 400006 Cloned-2009-03-24  ali follow..  24  25....PASDAFIFITGCDSGFGRLLALQLDQK---GFQVLAGCLTPSGAEDLQQMASS-----RLHTTLLDITDPQNVQQVAKWVKTRVGETGL----LVNNAGVAGIIG--PTPWLTQDDFQRVLSVNTLGPIGVTLALLPLLQQARG---RVVNITSVLGRIAANG-GGYCVSKFGLEAFSDSLRRD--GVQVSIVEPGFFRTPV....................................................... 212
69 -32.200MA0019U NP_976059.1 400294 Cloned-2009-02-26  ali follow..  20  48SAAEPVGSKAVLVTGCDSGFGFSLAKHLHSK---GFLVFAGCLMKDKGHDGVKELDSLNSD-RLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGI----TFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKG---RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE--GVKVSVVEPGNFIAAT-SLYSPESIQAIAKKMWEELPEV................................ 267
70 -32.100MA0019BF NP_001116155.1 400261 Selected-2008-12-22  ali follow..  20  53.....ASGKAILITGCDSGFGFSLAKHLHSK---GFLVFAGCLMKDKGDAGVKELDSLKSD-RLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGI----TFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKG---RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE--GVKVSVVEPGNFIAA........................................................ 244
71 -31.900MA0019AY NP_081577.1 400190 Selected-2008-12-22  ali follow..  23  21...KNLSEKYVFITGCDSGFGNLLAKQLVDR---GMKVLAACLTEEGAQKLLQDTSH-----QLQTFLLDVTKSENVKEAAQWVRDQVGEQGL----LVNNAGVGLPSG--PNEWLTIKDFVKVININLVGLIDVTLNMLPMIKKARG---RVVNMSSSGGRVAIFG-GGYCVSKFGVEAFSDSIRRE--GVKVSIIEPGNYKTSI....................................................... 209
72 -31.800MA0019D NP_065715.1 399869 Purified-2009-03-14  ali follow..  19  21FCPDLLRDKVAFITGGGSGIGFRIAEIFMRH---GCHTVIASRSLPRVLTAARKL-AGATGRRCLPLSMDVRAPPAVMAAVDQALK----EFGRIDILINCAA-------CPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHG--GVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEPQNIRVNSLAPGPISG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPASYVTGAVLVA.. 267
73 -31.400MA0019AF 18257359 400013 Purified-2009-03-27  ali follow..  19  21FCPDLLQDKVAFITGGGSGIGFRIAEIFMRH---GCHTVIVGRSLQKVTTAAKKL-VAATGKRCLPLSMDVRVPPEVMTAVDQALQ----EFGKINILINCAA-------CPASALSFNAFKTVVDIDTIGTFNVSSVLYKKFFRDHG--GVIVNITATLSMRGQVLQLHAGAAKAAVDAMTRHLAVEPQNIRVNSLAPGAIGTEGLRRLRGSNASSKLKHFSNPIPRLG---TKTEIAHSVLYLASPASYVSGIVLVV.. 267
74 -31.000MA0019T NP_004484.1 400289 Cloned-2009-02-26  ali follow..  18  7....SVKGLVAVITGGASGLGLATAERLV---GQGASAVLLDLPNSGGEAQAKKL-----GNNCVFAPADVTSEKDVQTALALAKG----KFGRVDVAVNCAGIAVAYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDPIGIRVMTIAPGLFGTPLLTSLPEKVCNF------SQVPFPSRLGDPAEYAH-LVQAIIENPFLNGEVIRL.. 253
75 -31.000MA0019L NP_062519.2 399970 Purified-2009-03-27  ali follow..  16  117LQGRDFTGKVVLVTGANSGIGFETAKSFAL---HGAHVILACRNLSRASEAVSRILEEWHKAKVEAMTLDLAVLRSVQHFAEAFKA----KNVSLHVLVCNAGTFA--------GLTKDGLETTFQVNHLGHFYLVQLLQDVLCRS--SPARVIVVSSESPRSDYWAMLAYNRSKLCNILFSNELHLSPRGVTSNAVHPGNMMYSAIH..................................................... 332

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Li W, Jaroszewski L, Godzik A. Clustering of highly homologous sequences to reduce the size of large protein databases. Bioinformatics. 2001 Mar;17(3):282-3.