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Query: [R] KOG2852 Possible oxidoreductase, from COG0516

Results of FFAS03 search in JCSG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSNSRNIVIVGGGITGVSCLYFLAHHPSFNRDRDTITLFESAGIASAASGKASGFLSLEWHGPSTSSLAALSYNLHKELSDQYDGVNKWGYRALDTWSIKADENCQQPDKLPEGIEWIAPSIVENVTRLGNKKNSGQVHPYKFCHAIYEEASKVANVTLVKGHVLSVDENEVEYRLIGDDYAPDEEEEITSAEELHTIHSMEATHIIVAAGPWTPQLIPNLRISGARIHSITIDLPIKLNGNAVFSEITYKDGTIAAPEFYAREDELYVCGEFDDEPLPELSSDTKVDQDKCALIKQCANHFHQIIRDSPVKVRQACYLPISNATGAPVIGKIGSSIYVAAAHGCWGITLGPGTGKVLSELILDGAVTSANIDLLDPEGSLELast
1 -60.500FP11970A NP_391143.1 382587 Purified-2007-11-28  ali follow..  18  2....KSYIIVGAGILGASTAYHLAKT------GARVTVIDRKEPGQ-ATDAAAGIVCPWLSNQDWYQLAKGGARYYKDLIHQLEKDGESDTGYKRVGAISIHTDASKLDKMEEDITRLSASETKKLFPILADSGAARVNGRALCRSLLSAAEKRGATVIKGNASLLF-------------------ENGTVTGVQTDTKQFAADAVIVTAGAWANEILKHFQVSFQKAQIMHFEMTDADTGSWPVV-------PPSDQYILSFDNGRIVAGATHENDA----DDLRVTAGGQHEVLSKALAVAPGLADAAAVETRVGFRP-FTPGFLPVVGAVPQGLYAANGLGASGLTMGPFLGAELAKLVL-GKQTELDLSPYDPAGAL. 371
2 -56.100TT5625F NP_436430.1 404576 Selected-2009-08-14  ali follow..  14  9PSQKWDLIVIGGGIVGCSTAFYAARL------GLRVLIVERDTPGSGQSGRNLGFVRQQGRDFRELPLAIAALRLWNDLEEDLG--RKVGWLRGGNVVLAANDRESKAKDFGLDTILLTSAQTREKLPFLSDASDGRAEPGRTTRAFFEAAVELGVSVILGAHVTQLELQAGN-----------------VHGVWVNDKLYRADRVLCSAGTGSGKLLRNLPQERIRATVARTLPAPGLTLTSCISLPFT--------GLRQDEKGAFIFSVAGGE-IAPSSEGARPAHYRVRQAQDELRQFVPQLAELAIEAVWAGVIDA-LPDVVPVMGHVYPGLLLATGFSGHGFGLGPMAGKIMAGLAAGHS-ASVDISGLSPSRFSH 425
3 -54.900TT5625B YP_775934.1 404766 Selected-2009-08-14  ali follow..  13  29FPAEADIVIAGAGIMGCAAAYYLGLR------GLKAVVLDKSRIAGQQSTRAWGFVRQQGRESAEVPLMMAGMRIWEGLEQALG--FDLEWRQGGCLYMADHEDDWASREHGLDTRTLTRAEIDERVRGLSTATDGQAEPRRVAAAFAARATAAGARFFEGCGVTAIETAGGA-----------------VVGVVTERGTIRTRRVICAAGATSFRLLDRLPQQAVRGTCMRTNVLPDVSASTIWGH---------GLGIRQRRNGTINLADDAAGPIEPRDPQPQPNRAHAPRALAKLKAIFPALKDAQIVEAWGGLIDV-LPDGIPVIDAPGSGLAIATGFCGHGFAMGPIVGRLLAEWADTGE-PSLDLSAFRARRFVD 445
4 -54.700TT11418A YP_290853.1 404302 Selected-2009-08-14  ali follow..  17  8.GAPRTAVVIGAGMVGLSTAWFLQE------RGVDVTVVDRDSVAAGASWGNAGWISPGLSIPGFIPINSQCLDAYDQLAEN-APITAAFEKRAQAADLLRELRLIRDSGQEIGFAEMTGDELRERMPQVSQDGQRYVDPGAYTKALGEAVVKRGGTLREGFTVTDIRPDSGA-----------------IAVRSTTGESVRGDVVVLAAGSWITGLARRTRVQAGRGYSFTVPTEQPVPGPLYLPAVRVA--------CTPYQGKLRVAGTME------RGPDDPLDPGRIRAIIASARPLMEGISWEDRTDEWVGPRP-VTPDGLPLIGATKPGVYVAGGHGMWGLTLGPITGRLLAEQITTGKRP-EALAAFDPLR... 419
5 -54.400TT5625C YP_778239.1 404336 Selected-2009-08-14  ali follow..  15  14PPASADVVVIGGGIIGVFTAYYLARR------GVSVALVEKGRIGAEQSSRNWGWCRQQNRDARELPMASKSIDLWERFAAESG--EDTGFHRCGLLYLSNDDEEEFAKTAGVTTYMLDSKQAAERGRATGRPTDGTADPGKAAPAVAAALIKLGGSVHQHCAARGIELEGGR-----------------VAGVVTEAGVIKTRTVVMAGGAWASSFCRRFPQASIRQSILSVSPVETPLPDAMLTPQFLRFAPQFVPMFAKRWRNLLPGGLEGVRGGHETLLDPKPDMPTVTETYRRAAELLPELRDAKITHAWAGFVDS-TPDGVPGIGEVPPGLILAAGFSGHGFGIGPGAGHLIADLASGAQ-PFVDPAPYRPGRFSE 432
6 -53.500TT5625D YP_439657.1 404468 Selected-2009-08-14  ali follow..  14  12FPAQADVVIAGAGIMGCAAAYYLGLR------GIKAVVFDKSRIAGQQSTRAWGFVRQQGREAAEVPLMMAGMRLWEGLERELG--ADLEWRQGGCLYIAGNDDEWASRTHGLDTRMLARAEIDAHVSGLAAASDGQAEPRRVAAAFAARAAEAGARFVEGCGVTAIDMSAGA-----------------VTGVVTERGSVKARRVICAAGATSLRLLDRLPQQAVRGTCMRTNALPAVSASTIWGH---------GLGIRQRANGAINLADDMQVDVDPRDPNPQPNPAHAPRALAKLKATFPALRDAQIVEAWAGLIDV-LPDGIPVIDAPRDGLAIATGFCGHGFAMGPIVGRLLAEWVDTGT-TSLDLSAFRAARFVD 426
7 -53.000TT5625E YP_110945.1 404853 Selected-2009-08-14  ali follow..  14  18FPAQADVVIAGAGIMGCAAAYYLGLR------GIKAAVFDKSRIAGQQSTRAWGFVRQQGREAAEVPLMMAGMRLWEGLERELG--ADLEWRQGGCLYLADNDDDWASRAHGLDTRTLARAEIDAHVSGLAAASDGQAEPRRVAAAFAARAIEAGARFFEGCGVTAIDTSGGA-----------------VAGVVTERGVVKARRVICAAGATSFRLLDRLPQQAVRGTCMRTNPLPAVSASTIWGH---------GLGIRQRANGAINLADDMQVDVDPRDPNPQPNPAHAPRALAKLKAVFPALRDARIVEAWAGLIDV-LPDGIPVIDAPRDGLAIATGFCGHGFAMGPIVGSLLAEWVDTGA-TSLDLSAFRAARFVD 432
8 -52.600TT5625A YP_105916.1 404697 Selected-2009-08-14  ali follow..  14  18FPAQADVVIAGAGIMGCAAAYYLGLR------GIKAAVFDKSRIAGQQSTRAWGFVRQQGREAAEVPLMMAGMRLWEGLERELG--ADLEWRQGGCLYLADNDDDWASRAHGLDTRTLARAEIDAHVSGLAAASDGQAEPRRVAAAFAARAIEAGARFFEGCGVTAIDTSGGA-----------------VAGVVTERGVVKARRVICAAGATSFRLLDRLPQQAVRGTCMRTNPLPAVSASTIWGH---------GLGIRQRANGAINLADDMQVDVDPRDPNPQPNPAHAPRALAKLKAVFPALRDARIVEAWAGLIDV-LPDGIPVIDAPRDGLAIATGFCGHGFAMGPIVGSLLAEWVDTGA-TSLDLSAFRAARFVD 432
9 -48.200TT11970B NP_902493.1 403924 Selected-2009-08-14  ali follow..  12  4LAPGAAVIVVGAGVVGIAAALQLRLA------GFEVALLDRGEPAMETSYGNAGAFAVSDVIPALAALLGRVNDDYAALIERAGLGHLWRRHRSREEFDAAAPAWDDKRRHGVRWLALGRDALGEGEPVLREEWQYAVDPYVFSRGLFDAFLQEGGRFV-RDEALATAMEAGRVTGV----------------ETAGGGRLRADAVVIACGVWSDRFVKQHPLESERGYHVNLPKAGVALRHFI---QCASESFVILP---MAHGGLRLAGTVE------AHRDAPPDWRRAHILLDKARRIVGDFSTED-MTVWMGNRP-SLPDTLPIIGPAPPGLWFATGHGHLGLTLAATTGALLRDML-QGRAPALDMRPYRLSRF.. 418
10 -34.300FL11352A NP_244738.1 375369 Purified-2007-05-16  ali follow..  14  32...LVDVVIVGGGITGITTAYLLQK------RGKKVVILEADRLFNGTTGHTTAKITAQHGDEFIQHFGEDKAKQYYDAQMEFQEHDAYIYTNANRYLAKLEREMRAYEKLQINGSLIDSMPLQPIKKAIVMKGQAQFHPIAYLMKLVQDFIDRGGLIFEHTVATDVDKGEHRTV------------------LTRDGHKVTCDYVVESSHPFFDRGFYFSRMYADRSYVLGLKVKEPYPGGMYLSA---DPPRSIRHASYQGEDLWLISGETHKTG------QGMDTDYHYEALESFSREMFNV---TDISYRWSA-QDLVTLDRMPYIGPATSNILVATGFRKWGMTNGTIAAHVITDLIIGQVNAYQKL--FAPQRF.. 395
11 -33.900TM1432 TM1432 283292 Purified-2004-07-19  ali follow..  12  2.....KAVVIGGGVFGSLIARELTKYD------LEVTLIEKNDVGWGVTKANSAVVHAGYDDPPRAQFCASGNAMYEDLSKELD----FDFKRIGSFVVAFNDEELKELER-PGLTILERDEVLSMEPNLNPPTAGITEPWMVAIAAVENAVQNGLKLVLGESVVGFEKVNGRVRK-----------------VHTSRGEYEADIVINCAGLHADEIAEYVPLHPRKGEYILLKKLQGLVKRVIFP---TPTKISKGILVLPTVDGGILLGPTAEDLPEEMKDRPITTREGLEKVREFTRRLVPSLDFSLVVKTFSGLRPESPQKDFFI-SETVKNFVNVMATRSPGLTAAPAVAKYVVEELIQMRIPLEKKKDFKPER... 375
12 -20.600FP10738A NP_393992.1 382454 PDB-2008-03-06  ali follow..  12  2..ETYDVLVVGGGPGGSTAARYAAKY------GLKTLMIEKRP---GSPVRCGEGLSK---------------------------------GILNEADIKADRSFIANEVKGARIYGPSEKRPIILQSEKAGNEVGYVERDKFDKHLAALAAKAGADVWVKSPALGVIKENGKVAGAKIRHN-------------NEIVDVRAKMVIAADGF-ESEFGRWAGLKSSALQYRMINVDVDPDYTDFYLGSIAPAGYI----VFPKGEGMANVGIGSSINWIHNRFE-------LKNYLDRFIENHPGLKKGQDIQLVTGGVSVSKVPGLMLVGDAARLIDPITG---GGIANAIVSGMYAAQVTKEAIESN-DYSPQMMQKYEK 329
13 -17.600FP10549C YP_321149.1 382581 Crystal|NMR-2007-12-08  ali follow..  13  3.....DTIIVGAGPAGGAAAYHLAKK------GRSVLVLEKESLPRYKP--CGGGVSPI-------VAEWFDFDFSPAISLKVDS-----------------------------FRFTWNLEDPVEAKIETKEPVWMVRREVFDHFLVQQAQKQGAELRDNTEVTGIEFKSDYWQ------------------VNTANGPVTGRYLIAADGA-KGPMAKWLGFKERKRRLAGALEAEVPAQVKDKSTIHFEFGLVKNGYNFPKEEGYSI-GVGTFIGGQPQDFK-----KILVEYSQLFNIDVKTSKQYGHPIALWDGNQKLHTQNAILAGEAACVVDPMTAE---GIRPSIYSGVMAAGAVDQALSGDINALEQYTEIIQE 309
14 -16.300PU10368H YP_001049013.1 381095 Crystal|NMR-2009-09-06  ali follow..  13  24.VQHVDIAIVGGAMAGATLALALARLSLSAARPLSIALIEAHLPDKQHPGFDARSIAIAHGSIFELS----RLGLWPKLAHLGTAIENIHVSDRGHGMTELNAAQFHLDALG-------------------------VELERVGQVLFNELNKSEVKLYCPAKLAQVEPAVEGHTLV-----------------LDTGKRLKAKLVVAADGLQSSSFDLPVTQVAFEQTAIIANIQTDKPHQHLAYERFTQTGPLALLPMADSQGKPRLSLVWALDDARAKQMQTAPKAEFLAALQQAFGYRAGTFIDVSARHAYLSYMPRPIHHRCVFIGNAAQTLHPIAGQ---GFNLGLRDVVSLLEVLKTALDQGDDIGSAAVHAYLN 365
15 -15.300TT8204A NP_822828.1 404110 Selected-2009-08-14  ali follow..  12  17.RPERAAVVVGGGLAGITAALALADA------GVRVTLLEGRPRLGG---LAFSFQRGALTVDNGQHVYLRCCTAYRWFLDRIDAASLAPLQDRLDVPVLDAGGKPGRRLGRIGRSWLAAHGQSAVATLNAVAGDSSLGGELHDRLARKALDSVGVRTEVRTRVTSISLNGNG-----------------RWSVQVPGETLHADAVVLAVPQREAHELLPEGALDAPERLLEIGTAPILNVHVVYDRKVLSRPFFARTEASGLPEGQYLALSQSAAQ----DEIDEPVSVLRERYLPELERLLPATRGAQVKDFFVTRERTATFAPTPGVGRLRPGLCLAGAWTATGMESAVRSGVSAAGAALNA................. 459
16 -15.200TM1532 TM1532 283389 Purified-2001-11-19  ali follow..  13  1MKIEFDVVVVGAGPSGLSCAYVLAK------NGLKVAVVEKGE--PGSKNVMGGVLYVH--------------EIMPDFLEKAANSKALERNVIEQNLWLLGNEGVIKIGHRNV-------------EWKENPNAFTVLRANFDRWFAQEVEKAGALIIPKTKVEDFLRN----------------EKGEIAGVVTSKGEIHSKAVVIAEGV-NPILTMKAGLRKEHMVAVAVKEVISVPEDVVNRVFGVEGNDGATIELLGSWSEGMFGMGFLYANRSSVSLGCGVLLEDLRKKKIKPYQLLENLKNHPVISDMLGAMPKVYGDRVLVCGDAAM---LVNSIHREGSNHAITSGRLAAETLLEGDFSEKILKNYY...... 355
17 -15.200PC04820B SHEW_20DEC04_CONTIG148_REVISED_GENE1915 361144 Crystal|NMR-2007-01-12  ali follow..  11  10QTDHYDVIVIGAGPSGSVAASLLHQQ------GKRVLVLEKQHFPRFSIGES---------------LLPCCMQVIAEAN--LDAVNQAGYQFKNGAAFNANGRSTYFD---------------TDKFTPGPGTTFQVERGDFDKLLADTAASQGVEIRYGQRVDAVDLSHNPRL--------------TISDEQGASYELSADYLLDASG--GRVLPRLLDLE---------RPSNLPSRTAIFTHIQDNIDSVDMGDLIPFSNGRCSLGVVGEPHLQDADLEATNLEATLIRLVREEPRLKQLLSRAEKLAGYSANVSTLASDKFALLGNAGEFL------FSSGVTIAMQSASIAAKCVVK.................. 340
18 -15.000TT1532C YP_299340.1 404478 Selected-2009-08-14  ali follow..  11  3.....DVLVIGGGNAALCAALMARE------AGASVLLLEAAPKAGGNSQHTRNLRCMHDAPQDVLVDSYPEEEYWQDLLKVTGGITNEALARL-------------IRASSTCRPWMRRHGVHFQPPLSGALHVARTN-KALVNAYYRSAENLGVEIRYETPVDAIELDGSR-----------------FVAARSGAQRFQARTCVLAAGGFESEAGADAIGDPSQSHCVAIDARAPPYDGGICTRIDCVSLG-----VVVNRDAERFYDEGEDDTLPELARKLGLPEQAFVKSVADYNAGCRPGTFDHTTLDDCRTEGLTPPDTAPFYGEPSDNLF-VAGEMMAGNVLG-TAGVGMSIGTAFGRIAGTRAARAAAQA... 461
19 -14.900PE00357J NP_688430.1 368277 Purified-2006-06-01  ali follow..  2..KHYQTIIIGAGAAGIGFGSAMQRLGLTN-----FLIIEKGHIGE----------------------SFLRWPRTTQFITPSFTTNGFGFPDLNAVIPDTSPAFSFEKEHLSGVEYAR--------------------------YLQLVAAHYNLPIQNETSVLSIDKRDSLFV------------------IKTSKGDFSADYLIMATGEFQNPNTIDIKGADLGMHYGQVDNFHIKSDNPFIIIGGNESACDALTHLVYLGNQVELYTDTFGRKESNPDPSISLSPLTKERLKHIQDHKKEYYSSFHKPILSTGFLNTCHKNQLPIVTEIVNNCFLIGDTIFCYIYKFRQRFVPVINHIAQREGIILDEDTLEFFK... 357
20 -14.800PC04820A YP_679412.1 360961 Structure-2008-08-13  ali follow..  11  2QREKVDVLVIGAGPAGTVAASLVNKS------GFKVKIVEKQKFPRFVIGES---------------LLPRCMEHLDEAG--LDAVKAQGFQQKFGAKFVRGKEIADFN---------------SDQFSNGWNWTWQVPRGNFDKTLADEAARQGVDVEYEVGVTDIKFFGTDSVT-------------TIEDINGNKREIEARFIIDASG--GRVIPRMFGLDKPSGFESRRTLFTHIKDVKRPVAAEMEGNRITAVVVIPFSNGNTSVGFVGEPSY--FDEYTGTPEERMRAMIANEGHIAERFKSEETIEGYAISASKLYGDGFVLTGNATEFL------FSSGATFAMESGSKGGKLAVQ.................. 324
21 -14.800FP10572B NP_373108.1 382610 PDB-2008-05-05  ali follow..  10  2..QHHKVAIIGAGAAGIGMAITLKDFGITD-----VIILEKGTVGHS------------KHWPKSTRTITPSF-------------------------------------TSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYELNIFENTVVTNISADDAYYT------------------IATTTETYHADYIFVATGDYNFPKKPFKY------HYSEIEDFDNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTVKDIDFNNGQYHISFDSGQSVHT-TGFDATKNTNQDIKLTTHDPNIFMI-GATVENIYKFRARFAVLAHLLTQREGLPAKQEVIENYQ... 350
22 -14.800TM0787 TM0787 282657 Purified-2004-04-06  ali follow..  12  23.SLELDVAIVGAGPSGLTAAYELAK------NGFRVAVFEERNTPGGGIWGGG---------------MMFNEIVLEKELENFLKEVEIEYEVKEDHIV--------------------------------------VDSVHFASGLLYRATKAGAIVFNNVSVEDVAVQNGRVCGVVVNWGPTVRLGLHVDPI-----TVKASFVVDGTG----------------------------------------------------HPANVVSLLAKRGLVEMKTEFPMDADEAEKFVVDNTGEIFPGLLVSGMA--------VCAVHGGPRMGPIFGGMILS--------------GQKVARIVSE.................. 247
23 -14.700TT16378A YP_105848.1 404655 Selected-2009-08-14  ali follow..  11  1MSNNQDVVIIGTGIGGTTLGAILARH------GLRVAMIDSGTHPRFAVGES---------------TIATTTLTLELMAMRFDVPELKHITSIAEVSENVMPSCGVKRNFGFVYHREHTEQNPQEVNQALVVNEVHYFRQDIDAYMLHVAIRYGCDAYQNTVVDDIRIDAGGVTVT-----------------TRGGLTFEADFVADGAGY-RSVLADKLGLRGLFTHMIGVKPFDACREVPKALQQPVPWHQGTLHHLFDSKNPLVSVGLMLDPRKHPK--PDVRPEQEFADFIAKHPDMARQFADARAVREWVSSASACTGDRFCLLSHATGFI------FSRGLFNTMQTTNALAGLLIE----AAKDRDFSKARFAP 369
24 -14.300TT10368G YP_572089.1 404927 Selected-2009-08-14  ali follow..  13  3.RNRVDIAIVGGGLVGASLACALAP--LIERHGLRVAVIEAAPLNDAQAATFPSFDARASAIAQGSRRHFERLGVWATMAERATPIRQIHVSERGRGATRLTADEFDLDALG-------------------------IPNAWMGQVLHAALGALPLTWHCPARVDDIVPIADGHRLA-----------------LSDGACLEAGLTVLADGG-RSGLKERLGIASQAEQHALIANVEVGRDHGGVAYERFSSQGPMALLPMAGRRMALVWTHASERREDALAWSDDVCLRRLQDAFGDRLGRFRRIGRRDAYPLSLVTANEPVRPHLAVLGNAAHALHPVAGQ---GFNLALRGVMDLVATLEDGLSRGQAPGGAGLGEFEN 343
25 -14.000GD3006A YP_910318.1 388062 Selected-2007-09-21  ali follow..  1MTQKQSVVIIGGGPAGLTAAWELVKDG--GSEQYDVTVLEATREFGGRTVKHDGNRDPEIEDKVMLKRHRVSRIYWNRISLSANTLKAMGFKLTMVAGFSYLKSMVHKLPETNLENFYINRFGRKLYSMFFEGYTEKL-PGQLWETVESNCEAAGVKVITDANVVEIRQKDGKIASVVYEDSEGNRTEMAADDFISS---MPVKDLVNAVDASDHEIANGLPYRDFVTVGLLVKHLR--DPGYKVGRLQIFNN--WSPYLVKDVDNTVWIGLEYFCEEGDSFWNMT-DEEATKFAIQELTRMQVINGPQDVLDSHRERVKKAYPGNLYCVGRNGQHRYNNMDH-------SMATAIEAVKDIKSGETSKDNVWSVNTDK... 523
26 -13.800PU10368S YP_048575.1 381129 Crystal|NMR-2009-06-26  ali follow..  15  2..QSFDVVIAGGGMVGLALACGLQG------SGLRIAVLEKQAAEPQTLGKG---------ALRVSAINAASECLLRHIGENLVAQRVSPYNDMQVW------DKDSFGKISFSGEEFGFSHLGHI-----------IENPVIQQVLWQRASQLDITLLSPTSLKQVAWGENEAFIT-----------------LQDDSMLTARLVVGADGAHSQHADIPLTFWDYGHHALVANIRTEHPHQSVARQAFHGDGILAFLPLDDPHLCSIVWSLSPEQALVMQSLPVEEFNRQVAMAFDMRLGLCELESERQTFPLMGRYARSFAAHRLVLVGDAAHTIHPLAGQ---GVNLGFMDVAELIAELKRLQTQGKDIGQHLYRRYER 337
27 -13.500TT10368J NP_747300.1 404558 Selected-2009-08-14  ali follow..  13  2..SRVNLAIIGGGLVGASLALALQA--GARARGWKILLIEPFAPGDSYQ---PSYDARSSALSFGTQQIYQQLGLWQAIGRRAEPIRQIHVSDRGRGATRLDALEEGVPALG-------------------------VENAWLGQCLWQGLDSEVVSWRCPAEVTSMQAIERGYRLR-----------------LNDDTQLECDLAVLADGG-RSGLREQLGIHVRHQQSALIANITPGEAHGGQAFERFTEEGPMALLPLPENRCALVWTRQGMDARRLADIDERSFLRELQGVFGYRLGALRQVGARHLYPLSLIEAQEQVRPHLVVLGNAAHSLHPIAGQ---GFNLSLRDVQALAEALLAGPQQPGDLTTL--QAYHQ 334
28 -13.400TT10368D NP_253910.1 404014 Selected-2009-08-14  ali follow..  12  2..SKVNLAIIGGGLVGASLALALQA--GARERGWSIVLIEPFAPGNAYQ---PSYDARSSALSYGSRQIYERLGLWPAIAERAEPILHIHVSDRGRGATRLTAIEEGVPALG-------------------------VENAWLGQCLWKALDPEVVRWHCPAEVKTLEAREGGYRLT-----------------LDDETQLDCELAILADGG-RSGLREQLGIAVEQRQTALIANVSPSEAHLGQAFERFTPSGPMALLPLPDNRCALIWTRPGKDAERLRGLDDAAFLGELQAAFGYRLGAFRQVGARHCYPLHLVEAREQVRPHLVVLGNAAHSLHPIAGQ---GFNLSLRDTLALVDALLHDDAPLGEFAVL--QRYLD 334
29 -13.400TT10368H YP_166613.1 404450 Selected-2009-08-14  ali follow..  10  1MHESCDILISGGGIAGLTAAAAFGS------AGFSVICVDPAPPVTKRDVDG--------SDLRTTAFLQPAQVLLDNCG----------------------ARLADHAAPLQIMRIVDAGGEVPEPRVVRDFNAADLSDRPFGWNLPN-------WLLRREMVARLAELPNVDFRPGTATSSLFTRTAEARVGLSDGSRVTCKLVLAADGRSSPREAAGIGVKRYGQKALAFAVTHPIAHQNVSTEIHRSGGPFTLVPLPDWQGQPSSAVVWMERGPKALELLDMAPEAFEAAMTERSCGLFGPLKLASRRTIWSQSAERLSGERIALMAEAAHVVPPIGAQ---GLNMSLGDLRSLLELAQARPEDLGDAQML--AAYHK 342
30 -13.100TT10368A YP_410831.1 404667 Selected-2009-08-14  ali follow..  12  6YQYDYDLIIIGGGPVGMALALALRN------SGLSVLLLEARGLPEKAE------------DPRPLALSQGSRLVLQRLGKALSDVTPIF-NQGGLGRTVMMAREIGVPALG-------------------------VNYDEVFRAMHKALQKCKMDYLTGAQVTHMEASDGFGRVE--------------FEHEGITKKATARLLAVADGGRLTAQIEGITQQDYEQWAIVARVKTEHFEEHLAEQVSRTELSDAKQSLARVRTRAKAAEDAPRSHQPGVAYERFTPEGPVALLSPDRVQEILGLDDAAFLER-GRFVEAGKRSGFPLIGNAAQTLHPVAGQ---GFNLGLRDAWELAEEIMAFPAETGTPAML--ARYSS 377
31 -12.900SP16840A ZP_02036034.1 407171 Purified-2010-09-29  ali follow..  25  79..EEKNAYIVGSGLAALAAACFLVRDG--QMPGSHIHILEAMDI.................................................................................................................................................................................................................................................................................................................................................. 118
32 -12.800FP12963B NP_281743.1 382942 Crystal|NMR-2008-04-02  ali follow..  11  2..KKIDLIVVGAGPTGIGCAVEAKLK------NKEVLILEKSNNICQT------------------------------------------------------------MQFYKDGKRVDKAYKGCEGTNHGHVPFEDGTKESTIETFQNALKEHNIEVEFGSEVESVKNENGVFL------------------VSTAKGVYECKNIIVAIGRMGKPNKPDYKLPMTLTKIINFNANSVLGNEKILAEYAVDLANSNQVSLCYRKKEFTRLNDINLKDIHEAGNSGKVEGIDINEVEDDNGKAKVNFTDGTIIYAIGGSTPNVDDKGVPLMDEN-KGIFVAATKNGASIVTGLNDAVKILSVL.................... 311
33 -12.600TT5886B NP_630883.1 404365 Selected-2009-08-14  ali follow..  10  1MTAPAPVVVIGAGPIGLAAAAHLLER------GLRPLVLEAGPTAGSA-----------VSEWAHVRLFSTWGEVVDPAAEKLLTPTGWSR---------------------------------------PDSSTYPSGGDWVKHYLQPLADTLGDQIRYGARVTGVSKAGRDRVVDA---RDAQPYVVQVKHTDGREERITASAVIDASGTWSDHVTYRVP-ARYAEKRTAVIGSGASAFTALASLAELARSQNSATTVLRRGLSGSTYGGGEADQLPARGAKAAVDEGHAEAVTGFRTEAVRRLQAVDEVIVLTGFRPDLSPHGHRELSHPDSGVYLV-GMKSYGAMTGYEQVRSIAAALAGETEAADRVELVLPE.... 413
34 -12.300CL5886A 10175617 359068 Crystal|NMR-2005-10-09  ali follow..  13  2..NSLPVAIIGGGPVGLAAAAHLAVR------DVPFVLFEGKSEVGAS---------LEWK----------HVSLFSPWKYNIDRAAK---SLLEKESWKEPAGDRLPTGEQLVRDYLQP---------------------------LAETKALKPYIYTNAPVQSIYRKGIDKIKDHNRENTPFIIRYKQD---NDQKTLRARAVIDATGTWFSPNPIGAG-SRYEGKTILVVGSGHSAIHTLLDLAQLKEAAPSTLWAIRRNSPNGLFGGGQEDALPARGQLGLALEALLSKVVGVQNESPISLPLVDEIVANTGARPTVDPHGEKELRQPEKNFYIA-GVKSYGLATGYEQVRSIVASLAGSKKEAERVELQLPK.... 408
35 -12.100PL10368H YP_002549554.1 401110 Purified-2009-07-10  ali follow..  13  2..ETVDVTVIGAGLAGSVAALALAR------RGRKVTLVAGDT--RPKDRRTAALMDQSIR--------LDRLGLWEELKSQGEALSTMQIIDGTKRLLRAPPVAFRSSEIGLAA---------------------NFQNSDLLDVFDAALARESNLTVLHQQAASIDFSQDNARVT-----------------LADNTVIECDLVVGADGRHSMRGAANVAVRSYPQTAVVLNFTHTLPHNNVSTEFHTETGPFTQVPLKGNHSSLVWVVEPEEAELPLDDLSALVEARMQSLL--GQVTVEAPAQAWPLSGMSA----RYGKGRAVFIGEAAHAFPPIGAQ---GLNLSLRDIMALEDLVGHEPQKPLGSTLG--DRFDR 328
36 -12.100TT5886A NP_103575.1 404639 Selected-2009-08-14  ali follow..  10  3LQDDLPIAVIGAGPVGLAAAVHLMTR------GLPVKLYEAGDGVAAN-----------LRDWGHVRVFTPWRYCVDEAARRLLEAHGW----------RMPDAEAFPTADELVAHYLEP---------------------------LANLPELAPAIETKARVVAISRWGADKVRGS---ERGTRPFMLVVETANGTRRDSARAVIDASGTWADRIAYGIP-ALYAGRTTLVAGSGHSAANALLDLARLAETEPRTIWAVRGTDLVRIYGGGDADQLPESGRVQLVTGFATLAIRERDGRLIAQLGPVDRIIAATGQRPDLSPHGHRELSHPEPGFYTV-GIKSYGLLTGYEQVRSVAAALAGDMAAADAVQLVLPE.... 411
37 -11.900PE00349D NP_600384.1 367887 Purified-2006-07-26  ali follow..  13  1MSPNNDVCIVGGGPTGTLLAVLLGQK------GHRVTILEKWP----------------YERPRAVTFDHEIARILGYIG-------------DSENDEAIDYHSDSYDWKNAAGETLLEVDWTSMTDSGWRTRYWFYQPELEKRLRDLALTMDFVDIRCGFTAVGLSQDEN-----SAIIHGIVTDTPENIPADAQREDIRAKYVIGADGANSNSLGLEMNDLGYFFDWLILDLKPT-TDHWQLCDPKRPTTIVPGGPGRRRWEFMALPGEDLKELASEESAWNLLEPWDVTPGKAILERSAVYRFQARWAQEWRSGRALIAGDAAPFAGE--------------GMCAGLRDSLALADLVLSGKSDDALLDTYGEER... 346
38 -11.500TT13034A NP_105365.1 404065 Selected-2009-08-14  ali follow..  11  6.NSISSIIIVGGGASGVVMAAHLLKSP---NPDLRVTLIEK------RPHFGQGIAYSTLLSAHVLNVSAAGMSAYADDPGNF-------------------------------WRWLQGRGLVDPEQ---TPQTPFYAPRSLYARYLGELLD---------ELEAREQPTGRLRLIHEESLSITPTASGVEVALANGTSVVAHMAILATGRMGSEADTALD----ESRVMVLGTGLSMVDAFLALE---QRGHTGEIVAVSRRG--LLPSPHRKGNPIKLDVADIPLGTQLSYFVGWFRDLIRENQKAGI--DWRDVVDGLRPFNQKIWPASAKRRFVEHTKAWWDIRMAPEVYAKVTQAVQAGR................ 325
39 -11.100TT8204B NP_822198.1 404387 Selected-2009-08-14  ali follow..  10  7.GRTDHVVVVGAGLAGLSAALHLLG------AGRRVTVVERDLLPGGRAGVRGGYYRARFADGSTLDVHTGAEAMEAEIERFAGAREAAGYRQLLERLYRAQMRRFIDSNFDSPLQLLTPDLARLAALGGFGRLDARIPPARALAAYAVIAYPRGGMHALPRAMADAAAQAGAELRFGQDVTRLERAGDRITAVVTAYDRIPCDAVVLTPSAVVLHAGTDRTWPGLAHHTLSFGAAWGRTFDELTRSLLITRPTATDPGLAPPRHLHYILAPCPNTDIGPSAAAWGDLAPRYRDLTELEARGLDGIGSAHTFAQTGPFRPRNLVRGT-------ANAVLAGCTPGVGVPTVLLSGKLAAARVTGGTRRT............. 497
40 -11.000SP11366A ZP_02032779.1 413005 Selected-2009-11-12  ali follow..  12  27AVKEVNICIYGGTSAGVVAAYSAKKM------GKSVLLVEPGKYLGGMTTGGLGA----TDIGNKYAVTGLARLFYRRIGEHYNKFEQWTF-----------------------------------------------PPSVATATMNRFVKDADLDVLYYRRITNAKVQNKRIQSITLEDSQKPDKKTLI--------QVKAKQFIDCSY--EGDLMAKAGVSYFVGR......................................................................................................................................................... 188
41 -10.800B.SL21293A ZP_02430312.1 429794 Purified-2013-05-07  ali follow..  10  2....NRIGIIGGGASGIVAAIAAARSD----GDAQVFILEQKEIGKKILATGNGRCNLTNEAMDASCYHGEDPEFARNVLKQFGYGETLEF---------------------ASLGLFTKSRGGYIYPRSDQAAS-------VLELLEMELRRQKVKIYTGVRVEALKLSAKGFV------------------IRADGQRFPADRVILACGKSLGSDGSGYALARSMGHTLSPVVPALVQLKVKKHPFAKAAGVRTDAKVAALLGRQVLAEDTGEMQITAYGISGIP-------VFQISRHIAKGLYEGKEMKVRVDFLPEMEASQV-FNTHLDKCPYATCQEFLTGIFPKKLIPRLLELSHIRQNFPASELKPAQWEDLIR 330
42 -10.800FP12896A NP_953051.1 382616 Purified-2007-12-05  ali follow..  10  1MEQQMDVLIVGGGPAGIACAYLCHRN------DLSYLLIEQGKSVFQG------------------------TNTYPEGKNVYPSRPKESPEPFLVEELRPPDKPVAVEK--------------------------------YIQYVQHFVQHENLNIRTEVQFEDLKDARDHLI------------------VQTSVGNFAARKVVLAFGSSIPRELARTLVIGGGNTAAILRAKREAGDTQSVYWAHVAEKFDVNKETAQRLGEEILLGGNIRLLPGAIPRIGEVDQEGVDRLVIRVNEFTQP--GVQTIACAEGVCTVAKEGDRLILLNAEKGVYVI------GGAISPSFMKICG....................... 336
43 -10.700FP3654A NP_296342.1 382827 Crystal|NMR-2008-11-04  ali follow..  10  2..SLYDVAIVGAGPVGLAAAIGCKR------AGLSYVVLEKGCVVNAIF------------------------------------------------------------EYPTYMGFFTTAPELEIGNHPFVTGHDKPDRRDALMYYRLVTQRENLNVRQYTTVNKVHAAPAGFTL-------------EIEAQDGTPGVVEARRVVVATGYYDNPLSMGIPGEDSENVSHYYTEAHPFMGLNVTVIGAGNSAADAALDLWRSGVNVTMVVRAPELKSTIKYWVRPDLENRIKSIHAHFNSRVVEIHPEHVVVQLTGYRPDLSQPDECLVLTENPGLFVV-GSAGFAGKTNQENGRFHADHAVAEIERQLRSGELRPA.... 332
44 -10.400TM0427 TM0427 282300 Purified-2004-02-17  ali follow..  12  17...SLNTIVVGSGAAGLNAVDRVFSFGQKD-----VALLTDNLKWGTSRNTGS-----DKQTYYKLTLAGNVPDSVYELAETLFNGGSMDGDIALVEAALSARAFFRLVELGVPFPHSRYGEYVGYKTDHDPKQAGPLTSYYMCEKLLEEIRRKGIKIFEGYQVIGILTDRNEEKTIGLIALDLNNIDDPEKRYVL----FNVKNIIYATGGPAGMFYFHSPPVHFGATGIAFEAGVMGKNLTEWQ-----NLSGTYQQVIPRYVSTDENGNDEREFLEEYFPDPSTMLNAIRKIKNYGSSLIDILVFYETVIKGRRVNPSWGSKNGELLRKEYLEIGVCAQHNNGGLHGNIWWESNLKHFFPVGEVNGS............ 441
45 -10.400TM0600 TM0600 282473 Purified-2001-10-17  ali follow..  2...LKRLGIVGFGASAIGFINGLIESGK--VKDYRITVLERGK--GGEIYIPLEIQAKTVEFY--------KFSGYTPTVDKRVGIVNYLKSFERDGRKIEFGESFSDEEIYKRFYHHGFEPVKSYFFHLGTDILKET----NKNIYEYFSSFENIEFLFGTTVEDV-------------------EFGPPHRVHTNRGDFEFDELVIAVGRLMERLKEKYPQLVRPNQFVDIGVRYELPNHVMDPFSDMYEVKVRGKVTLEKYEDFTTVNGYSDSLHKTENTNFAIIRESLVDFVENLEKVIPGASYFDNLLYAVEVKFYTNKF----LNDIVEGLHVVSGWTR-SIQYATSMGYMRAVGMKI.................. 444
46 -10.300FP3654B NP_764723.1 382840 Crystal|NMR-2008-01-31  ali follow..  12  2..QTIESIIIGGGPCGLSAAIEQKK------KGIETLVIEKGNVVESI------------------------------------------------------------YNYPTHQTFFSSSDKLSIGDIPFIVEDSKPRRNQALVYYREVVKHHQLNIHPFEEVLTVKKINNKFA------------------ITTTKGVYECKYLTVATGYYGQHNTLEAEGAELPKVFHYFKEAHPYFNQNVVIIGGKNSAVDAALELEKAGANVTVLYRGEQYPKAIKPWILPNFESLVNKITMEFNATVTKITDHSVTYEKDGQLIEIDNDYV-MIGYHPENCYIA-GVIAAGIENGKYHGGVITQSILTKKQTPLE........... 327
47 -10.000TT10514A NP_105404.1 403963 Selected-2009-08-14  ali follow..  11  13VAAVEPAIVIGAGAAGLAVAQALIKA------GVPVAILEKESRLAEP------------------------HRRHQQLH-------------------------------------LNTHRDLSALPGLSYPGGTPAFPPKVIRHMNDFREANQLPVEFGVAVETLVFRGDHWA------------------VRTSAGSRLARHVVVATGRDKEPFTPQWQFTGRIIHSADFGDAQSYAGKKVLVLNHLAGVDTASLWLSARNGPALLPKRIGKIAVHRLSPLMARLPLRVADMAATQRLVFGDLTKFGMPPAPSGGASRLTSDYTAIAADDGAVDAIKSGK----ITVVPAIREFTRDGVINGSLVDPDI.......... 316
48 -9.690PU8204B EXIG_01APR05_CONTIG281_REVISED_GENE1694 380995 Crystal|NMR-2009-06-13  ali follow..  11  2...KQRVAVIGAGPGGLACAMLLAG------RGIDVTVYEKQPIVGGRTSQVGDYQ----RGPTFLNMPHILENLFTSIDLDMKDYLDL-YTLYFNGGKDHFTMTTDRDRMKQTIEQHFPGNGEGYDRFMAEQALKLMSANQIPEAMKRAVEELGGTVHLNTGISQLILDGTTA----------------TGVILESGEHVLYDDVVVGAKKWSRPKIDRKKFSDAPHHTIYFADDYEKNVREMTQTLELSDDFSFYVQNPSIIDSTLAPEGKSSVPVPNNYSELDWAIEG-PKLRRRVLDALEHRSPYTGVEAAIEVEEMFTPDDGHQLTQMMEHVYLVGGHPGSGLPTIFESARITADLLTS.................. 490
49 -9.440FL11426A NP_438844.1 375488 Purified-2007-05-30  ali follow..  10  2...NFDVAIIGGGLAGLTCAIALQQR------GKRCVIINNGQAAIDFASGSLDLLSRM-PAHPYSLLGAEKVLAKAQDFERLANELHLDLIGSTEKNHWRVTGLGSLRGAWLSPNSVPTVQGNEPFPVLGIEGYHDFQPQLLAANLVLNPQFEHCEVTSGFQLDELRKNAREFRSVNISQLLEHKLAFKDLVKEIIESAQGAEAVFLPAGLENQEFMTALSLLGMRQRIQLRHKFESLGGLMIINTRLLEDEEITADNFVLASGSFFSKGISEFDKIYEPVFESDIIGVEGFNNKDRFTWTAHRFAHPQ-VAINAQCQVKKCGTNLYAVGNVIGGFNALELGCGSGVAV--VTALAVADEILA.................. 431
50 -9.200GE8204A YP_001813199.1 396730 PDB-2010-02-04  ali follow..  15  2..SSKRLVIVGGGITGLAAAYYAERAF----PDLNITLLE-------AGERLGGKVATYREDGFTIERGPDSYVARKHILTDLIEAIGLGEKLVQTTLLTEEEKQEVADLLLHPSDSLRIPEQDIIEPLLSGIYAGNIDQMSTFATFVANEQKAGSLFELESLIERLEEVLERSEIRLETPLLAISREDGRYRLKTDHGPEYADYVLLTIPH-VVQLLPDAHLPELEQ----LTTHSTATVTMIFDQQQSLPIEGTGFVVNRRAPYSITACTAIDQKWNHSAPDHTVDEVLQQAVLQDLEKICGRTLEQVIISRLMDGLPAYTVGHADRIQRVRPGIYLALAYDGVGLPDCVASAKTMIESIEL.................. 462

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]