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COG3946
Query: [U] COG3946 Type IV secretory pathway, VirJ component, from COG0709

Results of FFAS03 search in JCSG0709
Master-slave alignment does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKQFKIRSVLQSIALLVLAGTAAAEPKPEKITHGRFEQIPVLRPDGEPQRVVIWFSDAGHVDQRTRQAEILRQDGAMVALVDTTHLYKVLAADSNHCTFSVGDVENLSRYLQAYYRDKTYRLPLLVGDGDGSGLVYAVAAQATENILAGVVSDGLCPVVVPTQAVCGAGVASDQHLKPAPVAAPLLVMTVSSAHCPAQLTSGFVRKVALGREIRLAASADLLPRLRAALRVLGAQKGVSLPPPPADLDGLPVVEVPSKAQKKSDTFAIFVSGDGGWAEIDKKVAGHLADADIPVVGLDSLRYFWSERTPEGFAKDLDRIARFYAHHWKRNRLLLVGFSQGADVLPAAINKLSPNTRQIIRMTALLSLGKYAHYEFHVSNWISTDDEGIPIAPDMVKLRSTRTVCIYGVDDQETLCPSLPQQNRRVALPGTHHFNGDYETVAKTILAQMEAAPLast
1 -36.900FK9667A NP_745507.1 371441 Selected-2006-07-12  ali follow..  17  12.....................................................................................................................................................................................................................................................DGAVGQIELLIDYPDGPPKGLVLVSHPQPLLHIVPLTLARQLRAAGWQVVRPSFRGVGQTQGTHDGEAEDCIAVIRHFNQQQPELPVALVGFSFGAYVFARVACALEG----QLQAVALMGLPVGDVPGGRY---------------YEPLPLPGDCLLLQGEQDEMAPLANLLQQRAVSVYAGANHFKGCLGRAAEQVIAHLAQ.. 211
2 -35.200PG9920A NP_636912.1 372467 PDB-2007-07-09  ali follow..  2......................................................................................................................................................................................................................................................................SRGHCILAHGFESGALKVTALAEVAERLGWTHERPDFTDLDARRDLGQDVRGRLQRLLEIARAATEKGPVVLAGSSLGSYIAAQVSLQVP------TRALFLMVPPTKMGPLPALDAA------------------AVPISIVHAWHDELIPAADVIASARLLLVDDGHRLGAHVQAASRAFAELLQSL. 175
3 -34.700MA4386A NP_853511.2 400010 Cloned-2008-02-06  ali follow..  16  26.................................................................................................................................................................................................................................................................AALRDGNPIIVYLHGSAEHRAASHKLVKVLSDGGFHVLSVDYRGFGDSTGKPEGLTTDAICVYEWTKARSGITPVCLWGHSLGTGVATNAAKVLEEK-GCPVDAIVLEAPFTNMWVASILMDALRKDKIIFPNDENVKFL-SSPLLILHGEDDRTVPLEYGKKVKMVIFPPGFQHLLCKSPTLLITVRDFLSK.. 252
4 -33.800FN9278A NP_069509.1 378945 Crystal|NMR-2007-10-13  ali follow..  15  12..................................................................................................................................................................................................................................................................ARIYVERALIVCHGLPYEPGSYTDLAGFFSKRGFPTLIFDFSGTGLSDGHFSAWVEDLLRIAENF------EEVSILGYSMGGAVAVRAAAELRN-----LRKMVVVSSPCCLDMFTEFKNLFLKEFTEIEPKNWIGDV-GAEKLIVHGRLDEIVPFNLAREPKAFVEVEKGDHFLRHDNRIVELIAEWLDG.. 229
5 -33.800PL3888B YP_002548124.1 401112 Selected-2009-04-08  ali follow..  12  18.....................................................................................................................................................................................................................................................GSDARSIAALVRAPAQDERPTCIWLGGYRSDMTGALEMDDLAASLGVGAIRFDYSGHGASGGTISRWLEEALAVLDHF----KPEKAILVGSSMGGWIALRLIQELKARHDTQVSGMVLIAPAPDFTSDLIFTRALMEDGRANRVMAGMIDT-GCPVHILQGMADPDVPYQHALKDVVLTLVRDGDH-PQDIDRMRNAIRAMIEPRP 269
6 -32.700PG9838A YP_001815388.1 372252 Purified-2006-10-26  ali follow..  11  27..............................................................................................................................................................................................................................................................LYSPALAGPAPLIVLFHGFPGKQLNM-DWAVQLQNLSFHVLVTSYRGTIGSPGAFRAIMQHVVSPEFTQAHDISADQISIVGHSMGGFAGLHAFIDVPD-----IAHYIGISPFNFGLIGQLVLDYLKRHHATWNLLSLKEQLGTRSALLVTSERDETSIKSLHHDAFEQIIVDSDHNYIENREDAFRAWTTWLRRR. 261
7 -32.700FN4107B NP_786288.1 379484 Purified-2007-08-07  ali follow..  14  9.....................................................................................................................................................................................................................................................KRDGLALQARLETPAAPSSTLVILMHGFTADMGFVPQLAQALVAHGLAVLRFDFNGHGCSEGRFINEIADAKAVLDEALTL-HYDHIVLAGHSQGGVVASMLAGYYPD----VVDKLILMAPAATLKSDLKVGGFYLRTAQQLPIYEVAQQY-AGSVTLIHVTADTVVSPQASEKHSQLHWVQDGGHSGDARATAIQLALAAFK... 249
8 -32.400FJ9474A YP_293260.1 370022 Purified-2006-10-14  ali follow..  14  51.....................................................................................................................................................................................................................................................WPTTETFRGLVGEPSGTPRGTAIVFHGNAGHAGHRSFYATALTRLGLRVILAEYPGYGSRDGAPGSLAADAQQTIALAHRL-YGTPPLLIGESLGAGVAALAGSRERDRIAGLLLITPWDRLEHVAAYHYPWLPVKWLIRDRYDSITYLASF-DRPVLVVVAERDSIVPANALPGPKQLMVVKAAEHISHVDDAWWQEAIDILLA.. 265
9 -32.300PU9670A YP_463941.1 381670 Selected-2007-07-06  ali follow..  14  1.........................................................................................................................................................................................................................................................................MLLYLHGFASGPSSTKTLAARFAGIGVPVDVPDLTPGEDGFESPSSMLAVAERRLAEAAP-----PHAVIGSSLGGYLAAVAASRDPS-----IERLVLMAPAFRLFERWRKRRLGWQFFEDAQGWPAFPEV-RVPTLCIAGRRDETIPLEDVAAGARLVEVDDGHELTSSLDLIFEEARAFLRPVT 211
10 -32.200FM12209A NP_784982.1 377611 Purified-2007-06-19  ali follow..  15  23....................................................................................................................................................................................................................................................................AHATTVLIAITGVHGNNPFYVNIGKTLMAAGIDFIYAQTRDAFNQVVS-DDANEDIAAYLSYAEEN-QYQHIILGGHSLGANKVIYYLANHADV---NVTKFLLLSPANLKRLTDMVSLSERNIIQKQADFSQIERI-RLSGAMVIGTLDTFTYGDPIKAENDLVFIQKTGHYQNKDQKLANEILKLIKN.. 282
11 -32.200FN4107C YP_546482.1 379496 Diffraction|HSQC-2007-11-01  ali follow..  16  14.....................................................................................................................................................................................................................................................NANGLKLAARLELPDIPPRGMAMIAPAFGCTKEIASRTARRLLQYGIGSLRLDFTGIGQSEGDFDTQVEDFVSAADWLRQH-VAAPNILIGHSFGGLVALNACHSIPE-----SRACVTIATPESPAHVLELRRQFADHARQFRLHDTMQRL-RVPVLIMHSPRDEMVPMETARHPKSLLAIEDADHMRPAAEFVASTIGLWGMR.. 254
12 -31.700GS9198H NP_266277.1 384112 Selected-2007-09-11  ali follow..  16  70.....................................................................................................................................................................................................................................................KNDGLKLDAWYVPAEHKTNNTVIVVHGFRQDKSAMRQYGQLFHELGYNVLMPDNRGAGQSEGKFITDKFDVIAWANYLTDKNPESQISLYGLSMGASTVMMASSE--KSLPSSVKNIIEDCGYTNAWDEITYQA-QGWFFQEASATKALTKD-KLPILLIHGSNDTYVPTSMVYEPKELLVIKGAAHFETNPELYRQTISKFMKANP 311
13 -31.500PG9968A NP_349623.1 372599 Purified-2006-10-26  ali follow..  17  15...................................................................................................................................................................................................................................................................GETSDKVYIFVHGKMSSKESAHEFATIAVERGYQVLSFDLPEHGERKNEDWNGVHDLKVIGDYAKRNW--KSISLFGCSLGAYFSLLAYKNFS------INKCLFQSPIVDMEHLIGPVEILSWDYYCYVKDHPIDKW-CVPTAIIYGTKDNLQSSYVIDTKSDLTVSVDSEHD--HTKEQAEAVIEWFKK.. 226
14 -31.500MA6031A NP_035974.1 400170 Cloned-2009-02-26  ali follow..  14  24.....................................................................................................................................................................................................................................................NADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAHMLKGLDMLVFAHDHVGHGQSEGDFQVFVRDVLQHVDTIQKDYPDVPIFLLGHSMGGAISILVAAERPT----YFSGMVLISPLVLANPESAKVCFGIQLLNAVARVERAMPRLTLPFLLLQGSADRLCDSKGAYQDKTLKMYEGAYH-PEVTNSVLHEVNSWVSCPP 303
15 -31.500PU3888A AFE_2494 381516 Purified-2007-08-22  ali follow..  17  47...................................................................................................................................................................................................................................................................ENHTDPVGIFLPGFASNMEGSQILARNAQAQGWSWVRFDPRGVGRSDGPFSRYLADLRLILHHMLQD---RPVLLVGSSMGGWLGTIAATRWPE----QIRALLLIAPAYNFI-ELHMRFDLVADSWRYDLLRFPPYL-HCPVEILHGSADEAVPLALSYRELAIRPLPGVDHLRGADATLLRSLQSLWTR.. 274
16 -31.500FN6031C NP_940317.1 379193 Purified-2007-11-14  ali follow..  12....................................................................................................................................................................................................................................................CVPYYLFMTMYWHHTSTTPVSTVLITHGYAEHQGRYSALVRSLLNYNFDVVTFDLPGHGYAPGPRDKLVDFHVALRHRAECRLRTETMCLFGHSMGGLITALSVLEDSS----NVSAVALSGPAFSPFPKTPMLRCSARIAPRLKVLAASQWDRSVPLLVMHGSADRLADIEGSRNGGTMRPVDGAFHNEPEAPQLRAELCEWLHAN. 279
17 -31.300FN12457A YP_753972.1 380045 Purified-2007-10-11  ali follow..  13  24....................................................................................................................................................................................................................................................................EQGKPAIIIMHGAAMNFYLGRFLPEILSEHGFSCLSANNRGHDFGTAPDKDCVKDVQALLHFLRSR-GYPRVILLGHSQAIPKLLYAQNQLQFP---EVQGMILVSPPPSVSKMMRYLTTFYGPNTPADTEELVKEI-YCPMLLIRGSMDFPPVSMELMHSVTIREINEASHYSGQEKQLGNTILEWLDS.. 278
18 -31.300PU4107B NP_250858.1 381575 Selected-2007-07-06  ali follow..  12  25....................................................................................................................................................................................................................................................................RAKVPGVLFVHGWGGSQQRDLKRAQGIAGLGCVCLTFDLRGHGAESGRQEDNLQDLLAAYDRLVAHIDSEAIAVVGTSYGGYLAAILSQLRA------VRWLALRVPAIYRDEDWLTPKLL-IPAASNRALQACAGF-RGDVLLVESEFDSYVPHSTIMSSLTHRIIDHADH-EAAQDAYTSILVDWITE.. 238
19 -31.200FK6031C NP_438805.1 371025 Selected-2006-07-12  ali follow..  12  42.................................................................................................................................................................................................................................................................QPESAVRKLMILVNGRAENMLKWSELAYDFYHQGYDVLLFDHRGQGYSQREFRFYVDDMAKIIEKVTALFSYSTQHLLAHSMGALIATYYLANYDH----HINKAVLSSPFYGILLKHPIFRWVHLCLNAIKRLPKVIPKIEIPILILQAEKEKIVDNKNLEKNARCEVILNAKH-DNVRRNVLKSVNHFLNV.. 311
20 -31.000PG9935A NP_470192.1 372513 Selected-2006-09-08  ali follow..  14  4..........................................................................................................................................................................................................................................................................CLCIHGFTGSPSEVKPLADYLREHDWDVLAPTLPGHDHLRHTYKDWIVFVDSILSQMLKE--DDEVYIIGFSMGGLLAGWLARHYPE-----VKKLVLLSTAVNAMEWPQIIENSKQFKKMVALAKPVFEHIEIPTFIAQGSADPIVPAEKSVGPKELFILEGSKHQDEQADKLFAAVLTFLQKD. 230
21 -31.000FN12654A YP_055307.1 379727 Selected-2007-06-05  ali follow..  10  10....................................................................................................................................................................................................................................................SRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVVADDHAGHGRTAMSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIARAMATRPNA----RLDGLALGGVVAQLRGLTRFLQGFADIYDMANGEGFYAAMPKIPIALFAGSEDPAGNLRRDGHDVELHLYDGLRH--ESRADVESSLVTFVDRV. 308
22 -31.000FK3618B NP_622099.1 371038 Selected-2006-07-12  ali follow..  12  12.....................................................................................................................................................................................................................................................GEDGADIYVHLWEPEEIYRGIIQIFHGMAEHGGRYQNFARYMNEKGFVVCADDHRGHGKTAGGFNKIVEDEYLIMKFLKEKYGNLPIVIFGHSFGSFVAQEFMIRYGK----EVNGVILSGSSAVKELPLRFYYFFKGLLNLYKPQRLLAIPKDLPLFIISGEEDPVGEYGKLVKQVNIKLYPGKRH-EVEREKVYEDILTWIGKR. 308
23 -30.900FK3618C NP_764535.1 371057 Purified-2006-12-13  ali follow..  14  10.....................................................................................................................................................................................................................................................VEDGTMLEVKIDKAKKSTIGIVHLFHGMAEHMDRYQELVEALNTQGYDVVRHNHRGHGKEIDENNQIVDDAYEIIETLYLEELNVPYIIIGHSMGSIIARSFVEKYPD----IAQGLILTGTGMFPKWKGVIYQTLKTMMKTVERQQLKRMDKELPILFISGKDDPFGEYGKGIKHITVQLYKHKRHFEEDYLKTWQHMFEWMEKQ. 302
24 -30.900FK4107B YP_604269.1 371332 Selected-2006-07-12  ali follow..  14  25..................................................................................................................................................................................................................................................................RSAPGWPSVVLLHGFTGNRALLPLFSRYLAARGVASLRFDFRGSGESQGDFSEMVEDTEAACAYLRGLLDPERVMLLGFSMGGLVAALAAERVRP------HRLALWAPALPELWLWPVGRAFLLEMPRLRPLEAAARW-GGVARVFHGDADTVCPPVFGVRGCDAVAIPGANH--EAVELLYRETGRFLLG.. 245
25 -30.900CL5874A 10173494 359055 Purified-2005-09-24  ali follow..  14  22.....................................................................................................................................................................................................................................................RLADEEVFIHHFEPLQKNNDIILLLHGYMDHSLTSARLINRLISEGFEVVALDWPGHGLSKGSFRQYNTIFLQLVQDMIERWGSDRIHLIAHSTGAGVVLDGLTNNLKKMP--TGGIVLTSPLIKLPSHR-PLTWFDAYLQWHEDMRRRAKCSAENVTILQGTRDTTVHWKANMKSAERILIDGGGH-DLIRELVFRFILKRLKKT. 285
26 -30.800FN3618B YP_264026.1 379742 Purified-2007-08-22  ali follow..  15  23...............................................................................................................................................................................................................................................................PSNSDTAISATLLIVHGMAEHSGRYADLAQFLADHGIAVATYDQLGHGKTVKPVQSLLKDVIVMADSLKVRHPNVPHFVMGHSMGSFIVRNVLKHHAR----NFTGAILMGTADANPLTKVFMTLFTLMDAGLHKNWAMTIAKDFPILLISGENDPIGDMGRGIRHVSVQLYPHMRHHEQNKEQVYQDILGWINNN. 309
27 -30.800FK9597A YP_832076.1 371254 Purified-2006-09-11  ali follow..  15  49.................................................................................................................................................................................................................................................................PESGGISATLITLHPLPTHGGFMDSSYRLPALAGVAVLRFNTRGTSSPRGTSEGERLDVEAAVRFAASR-DLPNRWLVGWSFGTELALMYGATDPVA--SLVEGAVLLSPPLHRATDAHLQEW---------------AASGKPMKVLVPEHDDYLQPAAAAEQAEVVGVDGAKHLWVG-SRVLNEIVDEVSATP 266
28 -30.800GS13637A YP_001087340.1 384041 Selected-2007-09-11  ali follow..  16  80.....................................................................................................................................................................................................................................................SSNNYKLESLFITSNIKTRDTMILVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTERYDLDSLVKFVKNKFPEGRLGVHGFSMGAGTAAMHSEI--NSKDDKVDFYILDSPYSEMKDAIRNKFKSGFWYSDVKPYESVEKS-NVPILFIHGTKDTVCNYQNSKKKKDLWLIEGIGHFEHDSTVYFNKIFKFIDS.. 319
29 -30.700FK9670A YP_322756.1 371453 Purified-2006-11-08  ali follow..  11  2........................................................................................................................................................................................................................................................................TQYIYLHGFASSPQSAKDIRQRFAQIHTQLTIPDLNAGEFSQLTITRQIQQIAATFPDDSV-----PITLIGSSLGGLTAAHLGQRYLQ-----VQRLVLLAPAFGFLSHWTSLPLSYNFVTDAAQYQEDHIQRPIPTLILHGKHDEVIPITASRDWVELIELDSNHALGNVMEEIWQAISLFCQLPE 213
30 -30.700FK9111B YP_526626.1 371450 Selected-2006-07-12  ali follow..  13.................................................................................................................................................................................................................................................................NAAQPQAPVLLLAHGAGAPSPFMEVLARELVQQGVSVVRFEFPYMAQRRIGGDTLIDFFREQIQLVTRH-LDCPLFIGGKSMGGRIGTMTAAQQP------VLGALGFGYP------------FHAPGKPAGNRVDHLADLNVPVQIIQGTRDPFGKPEDVQTSVNVHWLQTADHDFKP-TDAAEQAAQFIKN.. 212
31 -30.700MA8720A XP_904852.1 400472 Cloned-2009-02-26  ali follow..  12  13.......................................................................................................................................................................................................................................................GNKLLDAVCLVPNKNIAYGIILTHGASGDMNHLMSLASHLASHGFFCLRFTCKGLNIVHR-----IKAYKAVLNYLKTEYKLAGVFLGGRSMGSRAAASVMCHTEPDADDFVRGLICISYP------------LHHPKQQHKLRDEDLFRIKDPVLFVSGSADEMCEKNLLEKPSKIHWIEKANHSNDVFKEINTQILFWIQE.. 218
32 -30.600PU9227A NP_890928.1 381687 Selected-2007-07-06  ali follow..  13  3..........................................................................................................................................................................................................................................................................ILYLHGFRSSSFKARLLAQAMHQRGLA-GQWQCPQLPASPRQAAELA--LALAREQLAGQQDPRRLTVIGSSLGGYYATWLAERLGCQ-------AVLLNPAVQAARDLATQHFLPEYVEELRALYADPLTHPERYFLVAATGDEVLDWREMRPGCRQRIVQGGDHGLSDFPRWMPEVLEFALGSP 196
33 -30.600FK3618D YP_013873.1 371070 Purified-2006-12-13  ali follow..  13  9.....................................................................................................................................................................................................................................................ATDGLDLHLHIWDEVKNPVGVVQIVHGMAEHGARYGLFAERLNQAGYIVVADDHRGFGKSAIGFQNMVEDEAVVRTYLKESYPELPYFIFAHSMGSFIIRTFMAKHQVD----GVILSGSGLQPIALLKMGFHNLFEAVKVSQHKETLDRVPKDLPVLLLSGSDDPVGHFGKDTPDVTYKIYEGARHNELCKETVFQDVIDWLDEK. 302
34 -30.600FN6014E YP_508045.1 379429 Purified-2007-08-07  ali follow..  13  25..................................................................................................................................................................................................................................................................QTEGQHPPILFLHGYTSGAWQFQHWMPTLQANGWQSFALNLRGHGGSAGRELDYADDVARAIAYVRGQ-TDQTPILIGHSLGSVLARHYAAEHSV----PGLGLLITIGMRGNVERLMAQPDSDKVFMDLSKLKLGLPAKSTPTFVMAGTRDPIASVESVEAAVEPVMLQDKAHDGPDWNDGLQHLQAWLETA. 275
35 -30.500PG1022A YP_831045.1 372518 Selected-2006-09-08  ali follow..  13  18..................................................................................................................................................................................................................................................................HGPNARIGVAICHGFTGSPLSVMPWALHLAEQGFAVSVPLLPGHGTHWRGWREWAGAFENAYLELAGR--TDACYVAGLSMGGAVALRTASRHR------VAGVAVVNPGEDGDYSQTPLSAVHQLKKLFAAARRGLPRVTAPVLVFKSDTDEVVPPSSLEAELRVVPLPNSGHLDNDAPAIFGHSTTFFHEH. 252
36 -30.500ND8720A BC015148 369464 Purified-2006-07-26  ali follow..  12  13.......................................................................................................................................................................................................................................................GNKLLDAVCLVPNKSLTYGIILTHGASGDLPHLMSLASHLASHGFFCLRFTCKGLNIVHR-----IKAYKSVLNYLKTEYKLAGVFLGGRSMGSRAAASVMCHIEPDGDDFVRGLICISYP------------LHHPKQQHKLRDEDLFRLKEPVLFVSGSADEMCEKNLLEKPHKIHWIEKANHSNDVFKEINTQILFWIQE.. 218
37 -30.500PG4107A NP_623397.1 372426 Selected-2006-09-08  ali follow..  14  8...................................................................................................................................................................................................................................................TYNRKTLRGMLHLPEGVSEKVPMVVMFHGFTGNKVIFVKMSRALEKVGIGSVRFDFYGSGESDGDFSGELEDARQILDFVKRQTDVERIGLLGLSMGGAIAGIIARERKE----DVKALVLWAPAFNMPELIKLDRAFVEDIAKFNIFELSRGY-EGKVLIVHGTNDEAVEYRISDRNAFRVTIEGADH-LEWERKAIEESVKFFER.. 254
38 -30.500FK3618A NP_635767.1 371215 Selected-2006-07-12  ali follow..  16  17....................................................................................................................................................................................................................................................................ARPRGTLLLVHGRAGEPADTRSVLAALAQAGHAVYALDLRGYGGTARDGVRAMADVRATLTWIAKRHGLPPPALLGYSNGARVALLLAQTQPE----LLSALVLYGFPDDVDAAPQAAAVPAQPPRERTTAEAAEQVTRVPVLLLRGVDDPLATQSENAHDRSWVTLPHADHVEDSHAAWVDAVVAFLRR.. 274
39 -30.400PG9227D YP_001022386.1 372680 Selected-2006-09-08  ali follow..  11  2.....................................................................................................................................................................................................................................................................KPPSHLLYLHGFRSSSAKAQRVAAEVTRLQDAGHSLVWCCPQLPPS-----PAAAKALIDSLTHDWPSDRMAAIGSSLGGFYATVLAEQRGCR-------AVVLNPAVDPADTLA--EFTAAHVEELRVMRPPRLRDPARYLAVIAKGDEVLDWRDMTAGARIKLLEGGDHALSDFDDHLPDLLGFLDLG. 198
40 -30.300PU4107A NP_744385.1 381539 Purified-2009-01-30  ali follow..  15  39....................................................................................................................................................................................................................................................................GTKMPGILFVHGWGGSQQRDLARARHITGLGCVCMTFDLRGHEKTESQREQNLQDLLVAYDRLVSHVDSSAIAIIGSSYGGYLATLLTRERP------VRWLALRVPAMYWDDEWGSPK---LGPTDNRALAACAEF-GGDVLLVESEQDDYVPHSTLMNSLTHRIVDGADH-EQSQKAYSSLLAAWISEAP 267
41 -30.200FK9259A YP_168739.1 371156 Selected-2006-07-12  ali follow..  13  1......................................................................................................................................................................................................................................MLDMQASVVVEDFHFPSGSAQLSARLYLPAGTPQVAVVINGATGVPREYYQHFATWLAERGIACLTYDYRDFGHSLRGPDWALIDMPAAYAEMQRRYPDLPLWVIGHSVGGMLGPLQPGI------EPIARMICVCSGLVHHSDHPTPGAYLPEMGDRLPQADWSRS-GAPVDMFAFEDDTTIPPNCVWRLADVY-LREIGHFARRNAALWPRLI-----AP 286
42 -30.200FK9619A NP_785330.1 371318 Cloned-2006-09-15  ali follow..  11  14..........................................................................................................................................................................................................................................................ALEVVTTTHLDQPLPLVIFYHGWQSNKELVLTQARKLARKNLRVVLPDAMNHGERHQIVSGNLGEFELIVNYYRERILNEQIGVGGYSMGGMTTGALLTHHPE-----IKAATIIMGTPNLNAYAQLVR-LTSWLDHYDLNLQPETINHRPLLFWHGTEDERIPYSQSRNAEQVAFITGYQAKHLVKVPLMNKVANFFDY.. 247
43 -30.200PL3888A NP_945397.1 401883 Selected-2009-04-08  ali follow..  11  29....................................................................................................................................................................................................................................................................PGASPGLFWLGGFNSDMTGTKALDQWAEARGRACVRFDYSGHGESSGTIGRWLEESLAVFDAY----ARGPQILVGSSMGGWMALLLARALRRRGGDAAAGLVLIAPAPDYGEPYPITKALIEDGRNHLVLDGMIEV-GCPVRILQGKQDEDVPWRHAFDDVVLTMIQDGDH-PQDIARMLAAVEE...... 259
44 -30.100FK4107A NP_884891.1 371311 Selected-2006-07-12  ali follow..  12  25....................................................................................................................................................................................................................................................................RAKLPGVLFVHGWGGSQRFDLSRARDIAGLGCICLTFDLRGHAATEAQRRQVLRDIMAAYDALIAHVDTSAIAVVGSSYGGYLAAILTTLRAVRWLALHVPALYRDDEWAQPKLQLDRAAISAYRHATVAPEGNRALSRGDVLIVEAEHDDYIPHSTIMSSLTHRIVDGADH--RCQQAYSSILLNWATERP 250
45 -30.100FK6031D 17742323 371039 Selected-2006-07-12  ali follow..  14  38.................................................................................................................................................................................................................................................................ATRSIARGTVVLLHGRNECIEKYFETVADLTAMGFWVATFDTRGQGGSERRFSDYQRDISLFLEQVVLPDTRLPFFMIAHSTGALAALAAAPGLSN----RIDRLALCSPFIELDSQQSVPRSVIKTMGRVTRQDHLTNI-TVPTLILAPMLDTITPYKAQEEAAQLLPITGARH-DVFRKQALAAIDAFFAPE. 313
46 -30.100FK6031A YP_109099.1 371185 Selected-2006-07-12  ali follow..  14  19.................................................................................................................................................................................................................................................................PSCAAPRATVALVHGLAEHAGRYQAFAERLNAAGIEVVAIDLRGHGRSPGERDRYLDDADALVASAARE--NTPLFLMGHSMGGAIAALYAIERAAARHASLAGLILSSPALAPGRDVPPARTGAEILDAMRRIEAGRAALRLPVLVYHGTADKLTEPDGSRPDRTLTLYEGNYHNDLERERVIGALIDWIAAR. 275
47 -30.000GS9198G YP_878415.1 384027 Selected-2007-09-11  ali follow..  13  40..................................................................................................................................................................................................................GLKLTSPKREEIKNNPKNYGMNYENVIFKSKNEDVLLKGWWIPAQKQNKQIDSKKTIIFSHGYGNNRELVLTLAKKLCENGYNVLLFDFRASGESEGKVVTEKYDLLGAIDFVKNKKQSKEINLIGWSMGATTSILAGTESTD-----VKAIVADSPFGNLKDYLQLPKIRGFSIEDVDTIKAASNMSNKKLFLIHSKDDEAIPYENTEKCAEIWITNNAKHYSLYKDQYEKRIIEFFET.. 315
48 -30.000FK9259C YP_104528.1 371068 Selected-2006-07-12  ali follow..  12  2..................................................................................................................................................................................................................................SMHERPPITAETTRFAARDGRLLTGTFYAPGAPSASNGRSVLVSGALGVPRGFYERYARFLASDGFTVLTYDYRGIGDSRKPPDWGEADLPGALDHLAARAPSHRLLAVAHSVGGQLFGLAHN------NGRAAALLSICCPSGYWRLWPWPHRLWLAPLWFCVVPALGGVLRGRILAYTVSDDWMAPPAAVQALHRFYRRHAIGHFRDDNRALWPLGAAWLRE.. 294
49 -30.000PG9839A YP_049912.1 372256 Purified-2006-10-26  ali follow..  11  1.........................................................................................................................................................................................................................................................................MIIYLHGFDSTGNHEKVLQLQFIDEDVRLISYSTLHP-------RHDMQHLLKQVDKMIQHSDDDRSLICGVGLGGFWAERVGFLCDIRQ-----VIVNPNLFPQENMSGKIDRPEEYLDIATKCVANFREKNRDRCMVMLSRQDEMLDSQRSGEYYEIVWDDIQTHKFKSISPHLQRIKAFKTLG. 180
50 -29.900FK9363A YP_752533.1 371150 Purified-2006-12-13  ali follow..  13  79..................................................................................................................................................................................................................................................................DNPNSLTTLVFYQGNGMKEPHGLSVLTTLSTLNTDILVMDRRGLGASEGQPSNIIADAQQQLDYLHQQYQPEKVILHGYSLGSFIAADLAKN------NKIDALILHGSATNADDWVDMTLEMPEDFRKTDNKQVVAQYYQGPLLVIAAEEDEEVPPELSEKNKQLIMVPNVGHQG-DDANTMSQYQTFITE.. 286
51 -29.900FK3618E NP_869648.1 371143 Selected-2006-07-12  ali follow..  14  31....................................................................................................................................................................................................................................................................TRPRGRVVFLHGIVSHSGWYLASCDALAQNGFEVHFLDRRGSGGNPSDWRQWIDDVVCFLKTQPRD---VPLILGGISWGGKLASVLAAEHPD----LIDGLALVCPGIYAAQFPSSVRFALEDRKLTQHAREVAAMIRTPTWLVLAGRDRIVDNPKTREDKEYTCYEEAAHFEPDPRPYFRDLTNWVTRV. 281
52 -29.900FJ9259A YP_613958.1 369880 Selected-2006-06-19  ali follow..  12  23..................................................................................................................................................................................................................................................................PAHGPQRAAMVVHGATGVPQFYRHFAHWAAQQGIATLTYDYRDFGESLTGADWAVADQDAAQHKLAELAPTGPLWVLGHSLGGLGIAFHRY------PERVSRVITMGAGMTHYRDHPWHYLPKALAFWFLIGPVATGALEPPLELCVARDDDMVPPAAVRRYAAHFGLGTLGHLGAGCEAAWQDLMFPDAAE. 285
53 -29.800FN4107D NP_107121.1 379529 Purified-2007-12-14  ali follow..  10  39..............................................................................................................................................................................................................................................................LNRPCGIPAPAVVLMLHGFTGQKNLFAYAAAKLAEQGIATLRIDFNGSGDSAGNWSGQINDAMLAYDYLQTLVDGSRVGILGYSQGGLVASHVAALRPQ-----ASALVLWAPVTNPMSTFSLKAAFYKELPLFAPAVAISRY-HGPLRVVVGRREMIVAPQPAEGGVNDLVEVDSGHDWNAENVLIPSTVEWFGR.. 291
54 -29.800MA3888B NP_766099.2 400186 Cloned-2009-02-26  ali follow..  14  55............................................................................................................................................................................................................................................................PNLAYKRLKGKTPGIIFIPGYLSNMNGIKAVEEFCKSLGHAFIRFDYSGIGSSDGTVGKWRKDVLSILDDV----AEGPQILVGSSLGGWLMLHAAIARPE----KVIALIGIATAADGLVTFRIPYSFIKEAEHHCLLHSPIPV-TCPVRLLHGMKDEIVPWQRSLQDVDVILRKQGDH--ADIHLLICTIDDLIDVVP 297
55 -29.800PG6031A YP_001048449.1 372458 Purified-2006-10-27  ali follow..  11  47....................................................................................................................................................................................................................................................................PQAHTAIVLSSGRVESYLKYQELVFDLYQQGYSVYAIDHRGQGLSDRRFNDYIDDFALFMQKKVLPQNDKQLMLLGHSMGGAIGTLYLKQHPD----IFTAAAFSAPMYGIKLPMPTNRWLTESLDAADTCVLATAQIRTPILILQASEDKIVDNAAQNLHCQLKVIAGAAH-DAYRNQALNYALDFFKRF. 317
56 -29.800FJ9278A AE010300_3320 369901 Selected-2006-06-19  ali follow..  13  69.................................................................................................................................................................................................................................................................PKDSKPKGVVLQFHGNGENRTSHFMSLVWMVNYGYELVTLDYRGYLDSTGVPETIHKDSVDFISRELEYKRNIPMIIYGQSLGGAIALRATSELKN--KSGILLVVADGTFASYRKVFRQI----FMSDSLSPHETISALSAIPLLVIHGTEDEIVPYGLAGEPKWFWEVRGGGHDSKNFLSFLDNLIEKSKLNP 293
57 -29.600CL4107A NP_842165.1 359411 Purified-2005-07-19  ali follow..  13  11.....................................................................................................................................................................................................................................................CCHHDWLYGVLHLPQQPVTRGVLIVVGGPQYRRQFVLLARYLAERGIAVMRFDFRGMGDSDGEIEHVGEDLRSAADFFFSE-FLEDIVIWGLCDAASAALFHAHQ-----DSRVSGLVLLNPWVRTEQGIAKAYLKHYYLERLFDPEFWKKLLQGKILIITSGNDLTAREFLDLKQTELCHMESANH-REWRDQVTELTANRVLS.. 289
58 -29.600PK9227D YP_001182301.1 389558 Purified-2008-01-26  ali follow..  11  1.........................................................................................................................................................................................................................................................................MLLYIHGFNSSPFSDKMTAQYMAQHHPSVLFHQPQLPNTPK----AAMALLLEYVEAALKD--DEPLTYIGSSLGGYFASYLAEHYGGR-------AVLVNPAVKPFELFD-YQVLPEHKMEVAEFNTPVIRNPDRFLVLLQSGDEVLDYREALHHCQLRIEAAGDHSFVGYEHYLQTISQFLH-LP 191
59 -29.600FN6031A YP_612565.1 379953 Purified-2007-08-22  ali follow..  13  27.....................................................................................................................................................................................................................................................TQDGQRIRAGLWRSHGPSAGTILLFPGRTEYIEKYGPLAIDLTDRGFDVLTVDWRGQGLADREFGAFQLDVAALVAHAEALNLPRPWYLLGHSMGGAIGLRALHE-----GLPVAACAFTAPMWAIRIPFATVQWLSQAMLECADLRARPSP-DVPCVTFLGENEQIVATEAIHDSGKLEMIPDAQH-PQTRRQTCAILTAHFKK.. 313
60 -29.500FK3888A YP_509044.1 371322 Purified-2006-09-26  ali follow..  11  21....................................................................................................................................................................................................................................................................SGRRTGVVFLGGLRSDMTGSKALEAWARRSGREFLRFDYSGHGESSGCISDWADDAMAAIDAL----TEGPQVIVGSSMGGWISLLMAKHRPD----RMAGLVTIAAAPDFT-AMIITKRLIEDGRDHLILNDPLRI-DVPVRMLQGTADVDVTMDVALGDIRLELVKDADH--ACLDTITRAIEEVLTNA. 249
61 -29.500FK9227A YP_109572.1 371517 Selected-2006-07-12  ali follow..  10  1.........................................................................................................................................................................................................................................................................MILYLHGFRSSSFKARALAARLDELGRADEWRCP--------VLSVAPLAAIAAAEAEVAGVPAQRVTVIGSSLGGYYATWLAEKHGWR-------AVLLNPATQPQRDLR-IVVEPHHLDELNALHVAAISRPERYYLFAATGDEVLDYREMLPGARTRVIEGSDHGISEFADYIDDVLAFCDAG. 189
62 -29.500PK9227B YP_001337071.1 389834 Crystal|NMR-2008-05-03  ali follow..  2........................................................................................................................................................................................................................................................................ATLLYLHGFNSSSAKATALKTWLAQHYPEITMVVPELPPYPA--------ETAELLESIVLEHGGEPLGVVGSSLGGYYATWLSQCFML------PAVVVNPAVRPFELLNNFLGLESRHIYDLKVMQIDPLEAPDLLWLLQQTGDEVLDYRQAVASCRQTVEEGGNHAFVGFDDHFTQIIEFLG... 189
63 -29.500FJ9363A YP_564597.1 369946 Purified-2006-09-11  ali follow..  10  74..................................................................................................................................................................................................................................................................DNPNSHTLVFFIQGNGMKVDDSLAVLLTLSQLGTDIAIFDRRGLGASNGQAANLLTDAIQELTFIRHTYQPDKVIVHGYSLGSFIAAQLVKN------QAADALVMQGSATNVDDWIALTVETPESFKLVDNQEVVSKFYQGPLMVIGAEKDDQVPAELSEKIKSLIIVPKANHGE-NSAKTMQAYREFLAR.. 280
64 -29.500PG3888A MMAG_12JAN01_CONTIG3876_REVISED_GENE3831 372246 Crystal|NMR-2007-01-13  ali follow..  13  31....................................................................................................................................................................................................................................................................EGKTPGVVFLHGFHSDMEGSKALEAMCQAQGRAFLRFDYFGHGKSSGTIGRWAADAVAVIGEL----TKGPQILVGSSLGGWIALLAALEMKD----KVAGLVGVAAAPDFTEDWRIHRSLIEDGRNHLLLRDLIQI-HCPVWLIQGQKDEDVPWQTALEQVEIVLVKDGDHRDGDLIRLTNMVAAMLGM.. 260
65 -29.500PG3618A NP_251991.1 372612 Selected-2006-09-08  ali follow..  13  24....................................................................................................................................................................................................................................................................ATAVGAVMLSHGMAEHAGRYERLAAALNAAGYHFYAIDQRGHGRTAEGWGKVVGDLASLNHHIRQQHPELPIFLLGHSMGSYISMAYLLHHSC----SLQGAILSGSNYQPQALYRWVDLLGGLADITPPTHLRQIDADLPLLIIGGERDPVSQGKRLGRQVTLKTYPEARHNESNRDAVTQDLIDWLEQA. 303
66 -29.400FJ9227A YP_441716.1 370226 Selected-2006-06-19  ali follow..  10  1.........................................................................................................................................................................................................................................................................MILYLHGFRSSSFKARALAARLDELGRAHEWRCP--------ALSVAPLAAIAAAEAEVAGAPAQRVTVIGSSLGGYYATWLAEQHGW------RAVLLNPATQPQRDLRRHLGVEPHHLDELNALHVAAISRPERYYLFAATGDEVLDYREMLPGARTRVIEGSDHGISEFADYIDDVLAFCDAG. 189
67 -29.400PL9227D NP_907620.1 402022 Selected-2009-04-08  ali follow..  10  3..........................................................................................................................................................................................................................................................................FLYIHGFASSGESHKAKALKAGLAPYEVMTPTLSYVPSLAF------QTLRQLVDESLAQ--KEELTLIGASLGGYYATQLSWLYNLK-------AILINPAITPYETLK----WTHAHLEELKTLYTPHPDESKLLLLLQKGDELLNYLDALPKAKNIIEEGGNHQFQGIERHIEMILHFAKGED 188
68 -29.400PG9227F YP_316332.1 372898 Purified-2006-10-27  ali follow..  1.........................................................................................................................................................................................................................................................................MIAYLHGFNSSSGKARLLGEHMASLGREADYYCP--------ALPNSPREAVAFVEADLAQRHPQSITLVGSSLGGFYATYLAERHGWK-----AVLVNPAVHAHLLLRDALGPLTEAHLAELAALDVPAISRPERYLLLAQTGDEVLDYREAVAGARQIVETGGDHGFVGFERHFQTILDF..... 185
69 -29.300FK6031B YP_564667.1 371002 Purified-2006-12-13  ali follow..  12  50....................................................................................................................................................................................................................................................................EDNRRAIVISNGRVESYLKYQELIYDCYQQGFSVYALDHRGQGLSSRHFSDYVDDFKVFIERVVKPERHKELFLVGHSMGGAIATHYIHQDPT----TFNAAVLSAPMYGIILPLPTNQWLAEAIDAAKASIDMARGSPIPLLILQAGKDKIVCNQAQNK-CQRIIIEGAFH-DKLRDKALKALFDFINQH. 325
70 -29.300TM1022 TM1022 282889 Purified-2001-12-12  ali follow..  10  18....................................................................................................................................................................................................................................................................EGGNEGVLFIHGYTGSPHDFEYMAKEVNRAGFTVSVPRLPGHGTCGETARDWLRRAFDAYYDLKAIC--DRVYVVGLSMGGVIALILASQMN------PPKLVTLAAARKEYWSYNWPKQAAELYKLMKLARKSVSKITSATLVVAAKNDNMVPMKAAEEKRKLLVFEKSGHNDVEKEDVTRAVIEWLKGE. 253
71 -29.200FP4107B YP_299260.1 383165 Purified-2007-11-03  ali follow..  15  25....................................................................................................................................................................................................................................................................ATKLPGVLFVHGWGGSQEQYLARARKVAGLGCVCLTFDLTGHAGTRAQYERNLADVVAAYDVLARHVDRNAIAVVGSSYGGYLAAVLTSMRH------VRWLGLRAPALYMDEGWEHPK---VPPETNRALRACTAF-EGDVLVIESENDQIVPHAAVTSSMTYRVIKGADH--EHQRAYSSLLLNWLRE.. 239
72 -29.200GS9198J NP_815254.1 384136 Purified-2008-01-22  ali follow..  18  70.....................................................................................................................................................................................................................................................SEDGLRLKAIYLPADKKSNRTVIMAHGYMGSAETMSVFAKMYHDWGYNVLAPDARGHGKSQGDYIGDRKDYVQWIEKVLTEGQQEQITLYGVSMGAATVMMTSGE---KLPDNVKAIVEDCGYSTVNQELQTKLRAGYFFGEASAVKQLQKN-HLPMLFIHGENDTFVPFNATQGPKEKYVVPGAEHYNKNPEKYKETVAAFLDK.. 306
73 -29.200FK4107E NMUL_10JAN05_CONTIG15_REVISED_GENE1495 371056 Selected-2006-07-12  ali follow..  17  41.................................................................................................................................................................................................................................................................PEQAASRGILILVGGPQGSHRQFTLLARHLAANGIPVFRFDFRGMGDSEGDAENVKDDVRSGIDRLFAEISLNELVILGLCDAASAALFYAYQDPR-----VTGLVLLNPWVRTEEGSNCKSGCEAAPLPERMFQGLERF-QGRVLLILCGNDLTAQEFSELPHFSRFSLPEANH-REWRDQIARWTKEWLYS.. 307
74 -29.200CL5874B NP_248999.1 359528 Selected-2005-05-20  ali follow..  13  92....................................................................................................................................................................................................................................................................PEARGSLLLMHGYYDHMGLYRHVVDWALGMGFSVLACDLPGHGLSEGDFAEYQAVFKGLLGQAAELDLAAPWHLCGQSTGGAILLDYLLHGGE--RPELGETILLAPLVRPRAWG-PTAWVGALTRWVPRIERAPRR-ALSPLVVQGESDETVDWRHGLKEPRILLLEEARH-EGLRRRYFDFLSDALGA.. 339
75 -29.100CL6031A 6460342 359276 Selected-2005-05-20  ali follow..  16  22....................................................................................................................................................................................................................................................................ADPAGAVLLTHALAEYAQRYQDLIPALNAAGYSVYSYDLRGHGASPGDAFVQVDDHLAARAALRERCPDLPLYLFAHSAGALFTAGSVMADPQ----GISGVILSSPMLQAGQDQITLLTASTMMQLSQQLWPTYSNWALPTLVFYGTGDQVSYMDGLPDDKALKVFKGGYHNDCDREEVLALILDWLWER. 276

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ye Y, Osterman A, Overbeek R, Godzik A. Automatic detection of subsystem/pathway variants in genome analysis. Bioinformatics. 2005 Jun 1;21 Suppl 1:i478-i486.