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Query: [C] KOG2711 Glycerol-3-phosphate dehydrogenase/dihydroxyacetone 3-phosphate reductase, from COG0516

Results of FFAS03 search in COG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTVAALNKLSALSGSIQKSFSPKLISVGIIGSGNWGTAIAKICGENAKAHPDIFHPQVHMWMYEEKIQHEGKECNLTEVFNTTHENVKYLKGIKCPSNVFANPDIRDVGSRSDILVWVLPHQFVVRICNQLKGCLKKDAVAISCIKGVSVTKDRVRLFSDIIEENTGMYCGVLSGANIASEVAQEKFCETTIGYLPNSSVNPRYTPKTIQALFNRPYFRVNIVEDVPGVALGGALKNIVAVAAGIIDGLELGDNTKSAVMRIGLLEMQKFGRMFFDCKPLTMSEESCGIADLITTCLGGRNHKCAVAFVKTGKPMHVVEQELLDGQKLQGAATAKEVYEFLDNQNKVSEFPLFTAVYRIVYEGLPPNKLLEAILast
1 -128.000[C] KOG2711 Glycerol-3-phosphate dehydrogenase/dihydroxyacetone 3-phosphate reductase  ali  100  1MTVAALNKLSALSGSIQKSFSPKLISVGIIGSGNWGTAIAKICGENAKAHPDIFHPQVHMWMYEEKIQHEGKECNLTEVFNTTHENVKYLKGIKCPSNVFANPDIRDVGSRSDILVWVLPHQFVVRICNQLKGCLKKDAVAISCIKGVSVTKDRVRLFSDIIEENTGMYCGVLSGANIASEVAQEKFCETTIGYLPNSSVNPRYTPKTIQALFNRPYFRVNIVEDVPGVALGGALKNIVAVAAGIIDGLELGDNTKSAVMRIGLLEMQKFGRMFFDCKPLTMSEESCGIADLITTCLGGRNHKCAVAFVKTGKPMHVVEQELLDGQKLQGAATAKEVYEFLDNQNKVSEFPLFTAVYRIVYEGLPPNKLLEAI 373
2 -81.000[C] COG0240 Glycerol-3-phosphate dehydrogenase  ali follow..  27  2.......................KQHIGYLGMGIWGFCLASLLANKGY--------PVVAWSRNPD---------LIKQLQEERRH-PLAPNVVISPNLSFTTDMKEAIHNAFMIVEGVTSAGIRPVAEQLKQITDLSVPFVITSKGIE--QNTGLLLSEIMLEVLGDYLGYLSGPSIAKEVLNGSPCSVVVS------AYDSQTLKQIHEAFSLPTFRVYPNTDIKGAALGGALKNVIAIACGIAEGLSFGNNAKAGLVTRGLHEMRKLA-AIMDCKPETLNGLA-GLGDLCVTCFSSRNLRFGHLLAQ-GLTFEQAKAKI--GMVVEGAYTALSAYQVAKHHKI--DMPITTGIYRVLYENLDLKEGIALL 324
3 -11.700[S] COG4408 Uncharacterized protein conserved in bacteria  ali follow..  11  1.......................MSKLLMIGTGPVAIQLANICYLKSDYEIDMVG-RASTSEKSKRLYQAYKKEKQFEVKIQNEAHQHLEGKFEIN---RLYKDVKNVKGEYETVVMACTADAYYDTLQQLSLETLQSVKHVILISP-QFMSKFSQDIEVISFSTYLGDTRIVDKEAPNHVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKI----QLEVVESPLHAETRNSFMNDFSLKAIFPEG----TMTLIREMRLMWKEMMAILQA-FRVPSVNLLQF------MVKENYPVRPETLDEGDIEHFEILPDILQELLYVRYTAILIDPFSQPDENGHYFDFSAVPFKQVYKNEQDVVQIPRMPSEDY 363
4 -11.300[H] COG1893 Ketopantoate reductase  ali follow..  11  1.....................MEKPRVAVIGSGSIGLLLYAYLKLANW--------PALLVT---------NRPEQADHLNKEGLTFVAKSGEHQPISVTATPLSSFSAEEAEVGFITVKSFAVKALLPQLQRKK--WDGLVFFQNGMTHLEILRQIPARAICCGIVEIGAKRESDVRVQHTGDG---AIWIG----DMVGDSKNFDPMWACLHNAGLKAQKVTNWQDK-IANAAINPLTGLFRVKNGALIENQLFSLLLKELVKEACVTLGREREVDEHL---------------------YTRAICDKTANNLSSMYMDLTHHRRTEIESITGYLIKEAAKKGI--EIPNTSFVYHAV............. 295
5 -10.700[R] COG4007 Predicted dehydrogenase related to H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase  ali follow..  12  2......................STMKVAVYGAGN-GSRMAIEFAEAGH--------DVVLAEPARDMLDDAHWKVVEDA------------------GVTVTDNDAEAASEAEIAVLFTPFKKTFEIAKNITNHLPEGAVIANTC---TVSPVVLYYVLERELRRDRKDLGIASMPAAVPGTPQHGHYVIGGHSSSELDIATDEQISRCVELAESCGKVAYVVPADVSSAVADMGSLVTAVTSGVLDYYYVGTQIASLVETSGVNGMLKAMNPELLVRSAKSMHLLEEQEELDAALKWIEKGEIRHTDLVAAQALAKEIKNLMGGKAAEGT.......................................... 334
6 -10.200[E] KOG3124 Pyrroline-5-carboxylate reductase  ali follow..  13  2.........................SVGFIGAGQLAYALARGFTAAGILSAH-------------------------KIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGV-----TISSVEKKLMAFQPAPKVIRCMTNTPVVVQEG------ATVYATGTHALVEDGQLLEQLMSSEEDLIDAVTGLSGSGPAYAFMALDALAGGVKMGLPRRLAIQGAQALLGAAKMLL-GATIHALHFLESGGFRSLLINAVEASC-IRTRELQSMADQEKISPAALKKTLLDRVKLESPTVST...................................... 299
7 -9.490[E] COG0345 Pyrroline-5-carboxylate reductase  ali follow..  17  4........................QKIGFIGAGKMGSALMQGTIKAGIVTP--------------------------ENIGASDVYEPFLKDLQAKLGIRVSTDNAVIVRESDILILAVKPQTLSSVLSNLKNEITSEKLVISIAAGVPL---------STYEDALLEGTRVVRVMPNIAATVSEAASGIAPG-----KNATPEDLKAALEIFSAPESLMDAVTGLSGSGPAFIFPVIEAMAGAVLEGMDRKSALTAAQTVLGAAKMA-----------LETGMHPGELKDMVTSPAGTT------------QGIHSLEEAGIRAAFMNAVIRASERSKELGKK............................. 270
8 -9.290[R] COG2085 Predicted dinucleotide-binding enzymes  ali follow..  14  1...................MSHTKPSIAILGAGRVGSSLARSAVAAG---------------YEVKVAGSGAVDKIALTAEILMPGAV-------------PSTADQAVKDADIVFLAVPLHKFRSVNPAT-----EGKIVIDTMNHWVPVNGELEEISEIIAEFFGSTMVKSFNHIGYHEIEQDAGTGRAIAYATDDVDAGAQVAQLIKSF................................................................................................................................................................. 169
9 -7.920[I] KOG2304 3-hydroxyacyl-CoA dehydrogenase  ali follow..  10  1..MLSSTCTAAVRGLSTTAQLSKINNVTIIGAGLMGSGIAQVSANAKLNVTVVDSNQSALEKAQQGIANSLKRVAKKKHADDAAAQTALVSSVL--DRIKMSTNVSDSVKDADLVIEAIVENI-RKLFAEVEVAAKPTTLITTNTSSLRLADLNLKDKSRFGGLHFFNPVPMMKLLEVVRHTETSDATFNQLVDYGKTVGKTTVACKDTPGFIVNRLLVPYMFEALRGDASMEDIDVAMKLGAGYPMG--VGLDTCKFIMD................................................................................................................ 270
10 -7.740[E] COG0287 Prephenate dehydrogenase  ali follow..  9.........................RIALIGIGLIGSSIARDVRELGLA------RHVVISTRSEDTLKRAEELALGTDY---------------------TVSAAEAVKDADLVIVSVPVGASESVAQQIAPYLKPSAIVTDV-------GSTKASVIAQMAPHMPENVHFIPGHPLAGDAGFAGLFRERWCIFTPLPGTDAAALERLKDFWRALGSRVDEMDAEHHDKVLAIVSHL-IIAYNIVGTADDLETVTESEVIKGFRDFTRLAASDPTMWRDVCLHNKDAILEMLARFSEDLASLQRAIRWGEGDKLFELFSR------------TRSIRRSIIEAGQDVDTPDFGRHA................ 305

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]