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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|238922433|ref|YP_002935946.1| chromosomal replication initiation protein (EUBREC_0001) [Eubacterium rectale ATCC 33656] 453 COG0614 3-451 -117.000 33  [L] COG0593 ATPase involved in DNA replication initiation
H.sapiens 85-360 -10.400 13  sp|O75351|VPS4B_HUMAN Vacuolar protein sorting-associated protein 4B OS=Homo sapiens GN=VPS4B PE=1 SV=2
123-449 -11.300 13  sp|O43929|ORC4_HUMAN Origin recognition complex subunit 4 OS=Homo sapiens GN=ORC4L PE=1 SV=2
124-374 -12.300 14  sp|Q6P2S7|GNN_HUMAN Tetratricopeptide repeat protein GNN OS=Homo sapiens GN=GNN PE=2 SV=3 (Range: 301-600)
149-290 -13.000 19  sp|O43933|PEX1_HUMAN Peroxisome biogenesis factor 1 OS=Homo sapiens GN=PEX1 PE=1 SV=1 (Range: 451-750)
HGM_OVER 120-400 -4.600 12  PB005684 gi|160884252|ref|ZP_02065255.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]gi|156109991|gb|EDO11736.1| hypothetical protein BACOVA_02230 [Bacteroides ovatus ATCC 8483]
NEW_HUMAN_DOMAINS 148-257 -6.330 18  sp|Q7Z401|MYCPP_HUMAN C-myc promoter-binding protein OS=Homo sapiens GN=DENND4A PE=1 SV=2 (Range: 1715-1863)
PDB0614 7-453 -132.000 34  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dna
PfamA27U 5-71 -12.000 20  PF11638.3; DNAA_LAWIP/5-67; DnaA N-terminal domain
113-334 -112.000 60  PF00308.13; DNAA_STRCO/317-535; Bacterial dnaA protein
360-429 -36.300 42  PF08299.6; DNAA_PSEPU/414-483; Bacterial dnaA protein helix-turn-helix
SCOP175 111-329 -103.000 38  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
346-453 -47.100 24  d1l8qa1 a.4.12.2 (A:290-399) Chromosomal replication initiation factor DnaA C-terminal domain IV {Aquifex aeolicus [TaxId: 63363]}
VFDB 59-292 -13.400 17  VFG1663 (gi:28316243) y1093 - transposase Orf B, insertion element IS100 [Escherichia coli 536]
93-295 -14.000 13  VFG1729 (gi:26249443) c3608 - Hypothetical protein [Escherichia coli CFT073]
2 gi|238922434|ref|YP_002935947.1| DNA polymerase III, beta subunit (EUBREC_0002) [Eubacterium rectale ATCC 33656] 370 COG0614 1-368 -92.800 22  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
H.sapiens 136-362 -8.910 11  sp|P12004|PCNA_HUMAN Proliferating cell nuclear antigen OS=Homo sapiens GN=PCNA PE=1 SV=1
HGM_OVER 42-318 -2.860 PB019827 gi|67919427|ref|ZP_00513005.1| conserved hypothetical protein [Chlorobium limicola DSM 245]gi|67782966|gb|EAM42367.1| conserved hypothetical protein [Chlorobium limicola DSM 245]
NEW_HUMAN_DOMAINS 120-245 -4.980 15  sp|Q96NH3|BROMI_HUMAN Protein broad-minded OS=Homo sapiens GN=BROMI PE=2 SV=4 (Range: 941-1070)
PDB0614 1-370 -122.000 100  3t0p_A mol:protein length:371 DNA polymerase III, beta subunit
PfamA27U 1-119 -54.200 40  PF00712.14; DPO3B_BACSU/1-127; DNA polymerase III beta subunit, N-terminal domain
128-243 -48.600 30  PF02767.11; DPO3B_PROMI/129-244; DNA polymerase III beta subunit, central domain
245-364 -43.700 31  PF02768.10; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP175 1-119 -44.300 22  d1vpka1 d.131.1.1 (A:1-120) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
122-244 -50.600 17  d1vpka2 d.131.1.1 (A:121-243) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
245-366 -43.800 26  d1vpka3 d.131.1.1 (A:244-366) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
VFDB 9-328 -3.600 VFG0866 (gi:34148229) aatP - AatP permease [Escherichia coli 042] (VF0215)
3 gi|238922435|ref|YP_002935948.1| hypothetical protein (EUBREC_0003) [Eubacterium rectale ATCC 33656] 71 COG0614 3-70 -40.900 39  [S] COG2501 Uncharacterized conserved protein
H.sapiens 2-62 -10.900 13  sp|Q9P0P8|CF203_HUMAN Uncharacterized protein C6orf203 OS=Homo sapiens GN=C6orf203 PE=1 SV=1
HGM_OVER 1-69 -3.510 15  PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;
NEW_HUMAN_DOMAINS 30-69 -6.090 25  sp|Q8IUI8|CRLF3_HUMAN Cytokine receptor-like factor 3 OS=Homo sapiens GN=CRLF3 PE=1 SV=2 (Range: 281-442)
PDB0614 9-70 -40.900 35  1p9k_A mol:protein length:79 orf, hypothetical protein
PfamA27U 6-70 -45.400 56  PF13275.1; D4IXS8_BUTFI/4-68; S4 domain
SCOP175 9-70 -40.900 35  d1p9ka_ d.66.1.6 (A:) Hypothetical protein YbcJ {Escherichia coli [TaxId: 562]}
VFDB 1-65 -4.970 18  VFG1211 (gi:15599751) pilY2 - type 4 fimbrial biogenesis protein PilY2 [Pseudomonas aeruginosa PAO1] (VF0082)
4 gi|238922436|ref|YP_002935949.1| DNA replication and repair protein RecF (EUBREC_0004) [Eubacterium rectale ATCC 33656] 362 COG0614 1-359 -93.200 23  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
H.sapiens 1-291 -10.300 15  sp|Q9UQE7|SMC3_HUMAN Structural maintenance of chromosomes protein 3 OS=Homo sapiens GN=SMC3 PE=1 SV=2 (Range: 1-300)
3-211 -15.300 15  sp|Q8IY18|SMC5_HUMAN Structural maintenance of chromosomes protein 5 OS=Homo sapiens GN=SMC5 PE=1 SV=2 (Range: 1-300)
3-244 -13.700 15  sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo sapiens GN=RAD50 PE=1 SV=1 (Range: 1-300)
HGM_OVER 125-356 -3.200 13  PB000795 Q74Z21_ASHGO/1-280 PB000795; Pfam-B_795;
NEW_HUMAN_DOMAINS 270-313 -5.730 27  sp|Q8WUF8|F172A_HUMAN Protein FAM172A OS=Homo sapiens GN=FAM172A PE=2 SV=1 (Range: 21-79)
PDB0614 1-362 -112.000 28  2o5v_A mol:protein length:359 DNA replication and repair protein recF
PfamA27U 1-354 -15.800 14  PF11398.3; Q6D3T4_ERWCT/1-377; Protein of unknown function (DUF2813 topsan)
SCOP175 1-349 -24.300 20  g1f2t.1 c.37.1.12 (A:,B:) Rad50 {Archaeon Pyrococcus furiosus [TaxId: 2261]}
VFDB 1-356 -15.900 14  VFG0564 (gi:16767037) sugR - ATP binding protein [Salmonella enterica (serovar typhimurium) LT2]
5 gi|238922437|ref|YP_002935950.1| DNA gyrase, B subunit (EUBREC_0005) [Eubacterium rectale ATCC 33656] 645 COG0614 5-645 -151.000 53  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
H.sapiens 2-264 -50.900 24  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 1-300)
89-400 -61.700 18  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 151-450)
267-562 -72.600 26  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 301-600)
403-645 -58.600 30  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 451-750)
HGM_OVER 464-634 -5.040 14  HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;
NEW_HUMAN_DOMAINS 255-396 -5.900 sp|Q8N6G2|CM026_HUMAN Uncharacterized protein C13orf26 OS=Homo sapiens GN=C13orf26 PE=2 SV=1 (Range: 105-289)
PDB0614 3-644 -183.000 54  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA27U 230-400 -80.300 48  PF00204.20; Q9R3E4_ACISP/115-285; DNA gyrase B
540-640 -28.700 21  PF16898; F5HDJ4.1/657-784; C-terminal associated domain of TOPRIM
568-634 -43.600 49  PF00986.16; Q6MRR8_BDEBA/731-795; DNA gyrase B subunit, carboxyl terminus
SCOP175 9-229 -87.500 53  d1ei1a2 d.122.1.2 (A:2-220) DNA gyrase B {Escherichia coli [TaxId: 562]}
230-401 -80.900 47  d1ei1a1 d.14.1.3 (A:221-392) DNA gyrase B {Escherichia coli [TaxId: 562]}
415-635 -27.200 30  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 26-539 -9.890 12  VFG1568 (gi:23954252) orf34 - hypothetical protein [Escherichia coli 536]
6 gi|238922438|ref|YP_002935951.1| DNA gyrase, A subunit (EUBREC_0006) [Eubacterium rectale ATCC 33656] 852 COG0614 3-830 -200.000 43  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
H.sapiens 8-198 -40.300 29  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 601-900)
75-386 -57.000 23  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 751-1050)
230-507 -31.200 13  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 901-1200)
HGM_OVER 1-490 -2.560 PB002589 gi|91201099|emb|CAJ74158.1| hypothetical protein [Candidatus Kuenenia stuttgartiensis]
NEW_HUMAN_DOMAINS 38-184 -5.200 17  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1 (Range: 373-516)
PDB0614 1-505 -143.000 60  4ddq_A mol:protein length:502 DNA gyrase subunit A
31-742 -125.000 37  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
505-828 -65.900 39  3uc1_A mol:protein length:327 DNA gyrase subunit A
PfamA27U 33-464 -71.800 30  PF00521.15; A1ZXC5_9BACT/29-447; DNA gyrase/topoisomerase IV, subunit A
614-659 -13.600 47  PF03989.8; GYRA_HAEIN/641-686; DNA gyrase C-terminal domain, beta-propeller
SCOP175 1-513 -66.000 17  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
31-492 -127.000 56  d1ab4a_ e.11.1.1 (A:) DNA Gyrase A {Escherichia coli [TaxId: 562]}
507-809 -62.100 31  d1suua_ b.68.10.1 (A:) DNA gyrase A C-terminal domain {Lyme disease spirochete (Borrelia burgdorferi) [TaxId: 139]}
VFDB 45-766 -7.800 10  VFG1960 (gi:15792750) Cj1432c - putative sugar transferase [Campylobacter jejuni NCTC 11168] (VF0323)
7 gi|238922439|ref|YP_002935952.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (EUBREC_0007) [Eubacterium rectale ATCC 33656] 281 COG0614 7-281 -93.800 29  [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain
H.sapiens 26-232 -8.480 10  sp|P12111|CO6A3_HUMAN(removed signalp:1-25) Collagen alpha-3(VI) chain OS=Homo sapiens GN=COL6A3 PE=1 SV=5 (Range: 2551-2850)
HGM_OVER 8-162 -4.700 14  PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]
NEW_HUMAN_DOMAINS 91-163 -5.760 24  sp|Q9P015|RM15_HUMAN 39S ribosomal protein L15, mitochondrial OS=Homo sapiens GN=MRPL15 PE=1 SV=1 (Range: 210-296)
PDB0614 50-164 -7.510 14  2dbj_A mol:protein length:124 Proto-oncogene tyrosine-protein kinase MER pr
PfamA27U 10-281 -123.000 54  PF05681.9; A7VNZ1_9CLOT/21-293; Fumarate hydratase (Fumerase)
SCOP175 27-146 -7.650 16  d1u7ba2 d.131.1.2 (A:127-255) Proliferating cell nuclear antigen (PCNA) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 14-231 -4.900 12  VFG0467 (gi:16765196) sopE2 - Type III-secreted protein effector: invasion-associated protein [Salmonella enterica (serovar typhimurium) LT2] (VF0116)
8 gi|238922440|ref|YP_002935953.1| hypothetical protein (EUBREC_0008) [Eubacterium rectale ATCC 33656] 47 COG0614 1-47 -5.950 15  [W] KOG3544 Collagens (type IV and type XIII), and related proteins
H.sapiens 4-39 -8.580 13  sp|Q03692|COAA1_HUMAN(removed signalp:1-18) Collagen alpha-1(X) chain OS=Homo sapiens GN=COL10A1 PE=1 SV=2 (Range: 301-600)
HGM_OVER 1-47 -2.310 19  PB045813 Q5LF03_BACFN/1-275 PB045813; Pfam-B_45813;
NEW_HUMAN_DOMAINS 25-39 -6.370 40  sp|Q5VYV7|CT094_HUMAN UPF0492 protein C20orf94 OS=Homo sapiens GN=C20orf94 PE=1 SV=1 (Range: 1-54)
PDB0614 12-47 -5.600 19  3v7o_A mol:protein length:227 Minor nucleoprotein VP30
PfamA27U 1-41 -6.210 24  PF06637.6; PLVAP_HUMAN/1-442; PV-1 protein (PLVAP)
SCOP175 2-47 -4.610 24  d2r6gf1 e.70.1.1 (F:13-260) Maltose transport system permease protein MalF {Escherichia coli [TaxId: 562]}
VFDB 13-47 -3.660 29  VFG1104 (gi:15641774) VC1771 - hypothetical protein [Vibrio cholerae N16961]
9 gi|238922441|ref|YP_002935954.1| fumarate hydratase subunit B (EUBREC_0009) [Eubacterium rectale ATCC 33656] 183 COG0614 1-182 -85.900 37  [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain
H.sapiens 75-145 -6.650 27  sp|Q6P5Z2|PKN3_HUMAN Serine/threonine-protein kinase N3 OS=Homo sapiens GN=PKN3 PE=1 SV=1 (Range: 301-600)
HGM_OVER 9-57 -3.220 10  PB008806 Q5L9W8_BACFN/1-127 PB008806; Pfam-B_8806;
NEW_HUMAN_DOMAINS 55-166 -8.250 11  tr|E9PBY9|E9PBY9_HUMAN Uncharacterized protein OS=Homo sapiens GN=C10orf93 PE=4 SV=1 (Range: 41-150)
PDB0614 1-174 -84.400 43  2isb_A mol:protein length:192 Fumarase
PfamA27U 1-178 -88.600 42  PF05683.7; A0KKZ8_AERHH/379-585; Fumarase C-terminus
SCOP175 1-174 -84.300 43  d2isba1 c.8.9.1 (A:2-179) Fumarate hydratase class I beta subunit {Archaeoglobus fulgidus [TaxId: 2234]}
VFDB 2-159 -6.340 20  VFG0291 (gi:15645157) cag11 - cag pathogenicity island protein (cag11) [Helicobacter pylori 26695] (VF0060)
10 gi|238922442|ref|YP_002935955.1| putative oxidoreductase (EUBREC_0016) [Eubacterium rectale ATCC 33656] 329 COG0614 2-326 -79.900 19  [GQ] KOG2741 Dimeric dihydrodiol dehydrogenase
H.sapiens 22-329 -101.000 26  sp|Q9UQ10|DHDH_HUMAN(removed signalp:1-23) Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase OS=Homo sapiens GN=DHDH PE=1 SV=1
HGM_OVER 107-236 -4.740 15  PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;
NEW_HUMAN_DOMAINS 6-120 -4.520 13  sp|P60228|EIF3E_HUMAN Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens GN=EIF3E PE=1 SV=1 (Range: 139-291)
PDB0614 1-328 -110.000 24  3e9m_A mol:protein length:330 Oxidoreductase, Gfo/Idh/MocA family
PfamA27U 4-121 -45.500 22  PF01408.17; CBAC_COMTE/1-120; Oxidoreductase family, NAD-binding Rossmann fold
125-245 -18.100 PF08635.5; Q4PF44_USTMA/241-382; Putative oxidoreductase C terminal
SCOP175 3-185 -70.000 24  d1ydwa1 c.2.1.3 (A:6-133,A:305-360) Probable oxidoreductase At4g09670 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
128-290 -39.500 18  d1ydwa2 d.81.1.5 (A:134-304) Probable oxidoreductase At4g09670 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
VFDB 2-328 -42.500 14  VFG0038 (gi:33591351) bplA - probable oxidoreductase [Bordetella pertussis Tohama I] (VF0033)
11 gi|238922443|ref|YP_002935956.1| transcription repressor of fructose operon FruR (EUBREC_0017) [Eubacterium rectale ATCC 33656] 247 COG0614 1-240 -67.400 28  [KG] COG1349 Transcriptional regulators of sugar metabolism
H.sapiens 10-219 -9.690 17  sp|Q14232|EI2BA_HUMAN Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens GN=EIF2B1 PE=1 SV=1
HGM_OVER 8-163 -5.610 12  PB001025 Q1QFV3_NITHX/1-288 PB001025; Pfam-B_1025;
NEW_HUMAN_DOMAINS 5-52 -6.540 14  sp|Q12789|TF3C1_HUMAN General transcription factor 3C polypeptide 1 OS=Homo sapiens GN=GTF3C1 PE=1 SV=4 (Range: 615-711)
PDB0614 1-124 -15.400 15  4a0x_A mol:protein length:190 TRANSCRIPTION FACTOR FAPR
3-167 -9.960 12  3sqn_A mol:protein length:485 Conserved domain protein
79-220 -9.940 23  3ixq_A mol:protein length:226 Ribose-5-phosphate isomerase A
PfamA27U 1-114 -31.300 11  PF06163.6; Q8XAE8_ECO57/1-127; Bacterial protein of unknown function (DUF977 topsan)
75-232 -51.800 25  PF00455.17; A9CFA5_AGRT5/77-236; DeoR C terminal sensor domain
SCOP175 1-54 -15.600 18  d1sfua_ a.4.5.19 (A:) 34L {Yaba-like disease virus, YLDV [TaxId: 132475]}
79-212 -9.550 18  d1uj4a1 c.124.1.4 (A:3-131,A:206-227) D-ribose-5-phosphate isomerase (RpiA), catalytic domain {Thermus thermophilus [TaxId: 274]}
VFDB 1-240 -14.900 16  VFG0483 (gi:16764732) orf408 - putative regulatory protein, deoR family [Salmonella enterica (serovar typhimurium) LT2]
2-75 -20.100 12  VFG1552 (gi:23954236) prfI - PrfI protein [Escherichia coli 536]
12 gi|238922444|ref|YP_002935957.1| fructose-1-phosphate kinase (EUBREC_0018) [Eubacterium rectale ATCC 33656] 305 COG0614 1-304 -86.400 27  [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)
H.sapiens 4-297 -23.400 17  sp|Q9H477|RBSK_HUMAN Ribokinase OS=Homo sapiens GN=RBKS PE=1 SV=1
HGM_OVER 1-264 -4.330 PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
NEW_HUMAN_DOMAINS 69-227 -5.570 17  sp|Q8N8M0|CG052_HUMAN Putative N-acetyltransferase C7orf52 OS=Homo sapiens GN=C7orf52 PE=2 SV=2 (Range: 161-369)
PDB0614 1-304 -109.000 44  2abq_A mol:protein length:306 fructose 1-phosphate kinase
PfamA27U 22-279 -16.700 16  PF00294.19; ADK_YEAST/21-336; pfkB family carbohydrate kinase
SCOP175 1-304 -109.000 44  d2abqa1 c.72.1.1 (A:1-306) Fructose 1-phosphate kinase FruB {Bacillus halodurans [TaxId: 86665]}
VFDB 4-299 -22.500 18  VFG0483 (gi:16764732) orf408 - putative regulatory protein, deoR family [Salmonella enterica (serovar typhimurium) LT2]
13 gi|238922445|ref|YP_002935958.1| PTS system, fructose-specific, IIABC component (EUBREC_0019) [Eubacterium rectale ATCC 33656] 642 COG0614 7-252 -39.600 20  [G] COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain
172-300 -67.700 50  [G] COG1445 Phosphotransferase system fructose-specific component IIB
302-641 -113.000 55  [G] COG1299 Phosphotransferase system, fructose-specific IIC component
H.sapiens 1-148 -27.300 16  sp|Q8NBS3|S4A11_HUMAN Sodium bicarbonate transporter-like protein 11 OS=Homo sapiens GN=SLC4A11 PE=1 SV=2 (Range: 1-300)
1-322 -10.500 10  sp|Q96Q91|B3A4_HUMAN Anion exchange protein 4 OS=Homo sapiens GN=SLC4A9 PE=1 SV=2 (Range: 151-450)
7-272 -22.500 12  sp|P04920|B3A2_HUMAN Anion exchange protein 2 OS=Homo sapiens GN=SLC4A2 PE=1 SV=4 (Range: 451-750)
HGM_OVER 69-173 -5.350 PB011130 gi|88806557|ref|ZP_01122074.1| hypothetical protein RB2501_00756 [Robiginitalea biformata HTCC2501]gi|88783389|gb|EAR14561.1| hypothetical protein RB2501_00756 [Robiginitalea biformata HTCC2501]
NEW_HUMAN_DOMAINS 119-205 -6.410 10  sp|Q96KM6|Z512B_HUMAN Zinc finger protein 512B OS=Homo sapiens GN=ZNF512B PE=1 SV=1 (Range: 688-778)
PDB0614 1-149 -54.500 28  2a0j_A mol:protein length:149 PTS system, nitrogen regulatory IIA protein
173-278 -67.600 51  2r4q_A mol:protein length:106 Phosphotransferase system (PTS) fructose-spec
PfamA27U 5-146 -31.900 21  PF00359.17; A8AYR4_STRGC/491-627; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
319-641 -45.700 20  PF13303.1; Q1J8T2_STRPF/28-337; Phosphotransferase system, EIIC
SCOP175 1-150 -50.900 27  d1a6ja_ d.112.1.1 (A:) Nitrogen regulatory bacterial protein IIa-ntr {Escherichia coli [TaxId: 562]}
176-278 -67.100 53  d2r4qa1 c.44.2.2 (A:171-273) Fructose-specific enzyme IIABC component FruA, middle domain {Bacillus subtilis [TaxId: 1423]}
VFDB 300-572 -5.720 14  VFG1503 (gi:24528033) ORF52 - hypothetical protein [Escherichia coli 536]
14 gi|238922446|ref|YP_002935959.1| chaperone protein DnaK (EUBREC_0020) [Eubacterium rectale ATCC 33656] 586 COG0614 1-585 -177.000 53  [O] COG0443 Molecular chaperone
H.sapiens 4-482 -121.000 29  sp|Q0VDF9|HSP7E_HUMAN Heat shock 70 kDa protein 14 OS=Homo sapiens GN=HSPA14 PE=1 SV=1
226-531 -109.000 54  sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial OS=Homo sapiens GN=HSPA9 PE=1 SV=2 (Range: 301-600)
268-568 -85.400 43  sp|P11021|GRP78_HUMAN(removed signalp:1-18) 78 kDa glucose-regulated protein OS=Homo sapiens GN=HSPA5 PE=1 SV=2 (Range: 301-600)
HGM_OVER 87-243 -4.410 19  HGC00267 gi|163310129|dbj|BABD01000566.1|6.0 TMP00066;
NEW_HUMAN_DOMAINS 364-479 -9.160 18  sp|O43301|HS12A_HUMAN Heat shock 70 kDa protein 12A OS=Homo sapiens GN=HSPA12A PE=1 SV=2 (Range: 520-675)
PDB0614 1-585 -170.000 52  2kho_A mol:protein length:605 Heat shock protein 70
PfamA27U 4-585 -171.000 52  PF00012.15; HSP77_YEASX/32-633; Hsp70 protein
SCOP175 2-160 -64.600 58  d1bupa1 c.55.1.1 (A:4-188) Heat shock protein 70kDa, ATPase fragment {Cow (Bos taurus) [TaxId: 9913]}
160-354 -58.800 42  d1bupa2 c.55.1.1 (A:189-381) Heat shock protein 70kDa, ATPase fragment {Cow (Bos taurus) [TaxId: 9913]}
366-483 -72.900 65  d1dkza2 b.130.1.1 (A:389-506) DnaK {Escherichia coli [TaxId: 562]}
484-585 -32.000 20  d1dkza1 a.8.4.1 (A:507-603) DnaK {Escherichia coli [TaxId: 562]}
VFDB 2-350 -9.790 14  VFG1222 (gi:15600237) pilM - type 4 fimbrial biogenesis protein PilM [Pseudomonas aeruginosa PAO1] (VF0082)
15 gi|238922447|ref|YP_002935960.1| hypothetical protein (EUBREC_0021) [Eubacterium rectale ATCC 33656] 290 COG0614 7-249 -8.060 [YU] KOG4460 Nuclear pore complex, Nup88/rNup84 component
H.sapiens 1-194 -8.580 13  sp|Q5JTD0|TJAP1_HUMAN Tight junction-associated protein 1 OS=Homo sapiens GN=TJAP1 PE=1 SV=1
HGM_OVER 49-142 -5.580 PB001404 Q2S5L8_SALRD/1-256 PB001404; Pfam-B_1404;
NEW_HUMAN_DOMAINS 5-145 -6.170 sp|Q0VDD8|DYH14_HUMAN Dynein heavy chain 14, axonemal OS=Homo sapiens GN=DNAH14 PE=2 SV=3 (Range: 601-867)
PDB0614 2-198 -7.200 4cgk_A mol:protein length:392 SECRETED 45 KDA PROTEIN
PfamA27U 4-130 -8.700 17  PF11657.3; Q5NWI4_AROAE/1-144; Transcriptional activator TraM
SCOP175 5-149 -6.300 11  d1aepa_ a.63.1.1 (A:) Apolipophorin-III {African locust (Locusta migratoria) [TaxId: 7004]}
VFDB 41-149 -7.940 14  VFG1000 (gi:18462552) mxiN - putative membrane protein [Shigella flexneri (serotype 2a) 301] (VF0118)
16 gi|238922448|ref|YP_002935961.1| DNA-binding response regulator (EUBREC_0022) [Eubacterium rectale ATCC 33656] 230 COG0614 2-229 -79.600 35  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
H.sapiens 3-161 -38.200 14  sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2 (Range: 1-300)
3-207 -16.200 12  sp|O60658|PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8A OS=Homo sapiens GN=PDE8A PE=1 SV=2 (Range: 1-300)
HGM_OVER 105-223 -3.540 16  PB177066 Q891G9_CLOTE/1-159 PB177066; Pfam-B_177066;
NEW_HUMAN_DOMAINS 1-164 -30.800 12  sp|Q8TE77|SSH3_HUMAN Protein phosphatase Slingshot homolog 3 OS=Homo sapiens GN=SSH3 PE=1 SV=2 (Range: 101-251)
PDB0614 2-227 -87.200 32  2oqr_A mol:protein length:230 Sensory transduction protein regX3
PfamA27U 3-112 -25.800 24  PF00072.19; AGMR_PSEAE/4-117; Response regulator receiver domain
150-226 -26.300 32  PF00486.23; O85058_PROST/114-189; Transcriptional regulatory protein, C terminal
SCOP175 2-117 -54.700 38  d1zgza1 c.23.1.1 (A:2-121) TorCAD operon transcriptional regulator TorD, N-terminal domain {Escherichia coli [TaxId: 562]}
130-227 -43.700 34  d1p2fa1 a.4.6.1 (A:121-217) Response regulator DrrB {Thermotoga maritima [TaxId: 2336]}
VFDB 2-230 -90.000 33  VFG1563 (gi:23954247) orf29 - hypothetical protein [Escherichia coli 536]
17 gi|238922449|ref|YP_002935962.1|(removed signalp:1-29) hypothetical protein (EUBREC_0023) [Eubacterium rectale ATCC 33656] 428 COG0614 125-423 -39.700 17  [T] COG0642 Signal transduction histidine kinase
H.sapiens 151-428 -18.800 15  sp|Q5CZC0|FSIP2_HUMAN Fibrous sheath-interacting protein 2 OS=Homo sapiens GN=FSIP2 PE=1 SV=4 (Range: 4201-4500)
HGM_OVER 164-390 -4.660 PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
NEW_HUMAN_DOMAINS 182-410 -4.880 sp|Q5CZC0|FSIP2_HUMAN Fibrous sheath-interacting protein 2 OS=Homo sapiens GN=FSIP2 PE=1 SV=4 (Range: 4508-4797)
PDB0614 126-427 -34.300 18  4biu_A mol:protein length:298 SENSOR PROTEIN CPXA
177-423 -39.700 21  4q20_A mol:protein length:268 Sensor protein DivL
PfamA27U 206-270 -13.200 24  PF00512.20; Q55783_SYNY3/185-253; His Kinase A (phospho-acceptor) domain
221-422 -12.100 12  PF10090.4; A4YN87_BRASO/37-219; Uncharacterized protein conserved in bacteria (DUF2328 topsan)
SCOP175 196-273 -18.300 24  d2c2aa1 a.30.2.1 (A:232-320) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}
274-427 -21.700 24  d1bxda_ d.122.1.3 (A:) Histidine kinase domain of the osmosensor EnvZ {Escherichia coli [TaxId: 562]}
VFDB 110-427 -40.100 16  VFG1701 (gi:26249399) c3564 - Hypothetical protein [Escherichia coli CFT073]
18 gi|238922450|ref|YP_002935963.1| hypothetical protein (EUBREC_0024) [Eubacterium rectale ATCC 33656] 761 COG0614 44-761 -56.900 21  [CE] KOG0453 Aconitase/homoaconitase (aconitase superfamily)
H.sapiens 33-265 -27.900 27  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 1-300)
116-431 -38.300 26  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 151-450)
266-566 -21.300 19  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 301-600)
432-723 -14.900 17  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 451-750)
567-761 -10.700 19  sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS=Homo sapiens GN=ACO2 PE=1 SV=2 (Range: 601-780)
HGM_OVER 44-607 -3.450 10  PB002770 Q744K2_MYCPA/1-559 PB002770; Pfam-B_2770;
NEW_HUMAN_DOMAINS 266-318 -6.170 tr|F5H5G4|F5H5G4_HUMAN Uncharacterized protein OS=Homo sapiens GN=WBP11 PE=4 SV=1 (Range: 94-194)
PDB0614 44-761 -56.100 21  1aco_A mol:protein length:754 ACONITASE
PfamA27U 44-484 -26.100 21  PF00330.15; LEUC_YEAST/11-471; Aconitase family (aconitate hydratase)
545-695 -12.800 24  PF00694.14; ACON_BOVIN/582-712; Aconitase C-terminal domain
SCOP175 37-548 -37.300 18  d1l5ja3 c.83.1.1 (A:373-862) Aconitase B, C-terminal domain {Escherichia coli [TaxId: 562]}
44-488 -41.200 24  d1acoa2 c.83.1.1 (A:2-528) Aconitase A, N-terminal domain {Cow (Bos taurus) [TaxId: 9913]}
523-761 -14.000 19  d1acoa1 c.8.2.1 (A:529-754) Aconitase A, C-terminal domain {Cow (Bos taurus) [TaxId: 9913]}
VFDB 549-724 -7.180 18  VFG1411 (gi:15610124) leuD - leuD [Mycobacterium tuberculosis H37Rv]
19 gi|238922451|ref|YP_002935964.1| hypothetical protein (EUBREC_0025) [Eubacterium rectale ATCC 33656] 437 COG0614 39-404 -37.300 18  [R] COG0628 Predicted permease
H.sapiens 170-420 -24.900 15  sp|Q9H330|CI005_HUMAN Transmembrane protein C9orf5 OS=Homo sapiens GN=C9orf5 PE=1 SV=2 (Range: 601-900)
HGM_OVER 221-355 -4.930 18  PB001572 gi|163816107|ref|ZP_02207475.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]gi|158448527|gb|EDP25522.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]
NEW_HUMAN_DOMAINS 308-381 -6.540 18  sp|Q8TDJ6|DMXL2_HUMAN DmX-like protein 2 OS=Homo sapiens GN=DMXL2 PE=1 SV=2 (Range: 2314-2389)
PDB0614 277-405 -7.580 13  4hzu_S mol:protein length:166 Predicted membrane protein
PfamA27U 62-404 -39.900 18  PF01594.11; Y338_HAEIN/10-332; Domain of unknown function DUF20 topsan
SCOP175 194-381 -6.550 16  d1t3ta4 d.79.4.1 (A:221-429) FGAM synthase PurL, PurM-like module, N1 and N2 domains {Salmonella typhimurium [TaxId: 90371]}
VFDB 124-397 -6.350 16  VFG0813 (gi:15804230) escV - escV [Escherichia coli O157:H7 EDL933] (VF0191)
20 gi|238922452|ref|YP_002935965.1| hypothetical protein (EUBREC_0026) [Eubacterium rectale ATCC 33656] 877 COG0614 16-210 -12.300 16  [D] KOG1126 DNA-binding cell division cycle control protein
H.sapiens 10-215 -15.000 17  sp|Q9Y5Q9|TF3C3_HUMAN General transcription factor 3C polypeptide 3 OS=Homo sapiens GN=GTF3C3 PE=1 SV=1 (Range: 151-450)
18-264 -11.200 10  sp|O15550|KDM6A_HUMAN Lysine-specific demethylase 6A OS=Homo sapiens GN=KDM6A PE=1 SV=2 (Range: 301-600)
HGM_OVER 1-155 -4.890 14  PB128892 A6TNK2_9CLOT/1-174 PB128892; Pfam-B_128892;
NEW_HUMAN_DOMAINS 26-187 -8.030 14  sp|Q14674|ESPL1_HUMAN Separin OS=Homo sapiens GN=ESPL1 PE=1 SV=3 (Range: 717-845)
PDB0614 1-205 -12.000 14  3qky_A mol:protein length:261 Outer membrane assembly lipoprotein YfiO
16-189 -12.500 16  3as8_A mol:protein length:186 Magnetosome protein MamA
606-877 -23.200 17  3syk_A mol:protein length:309 Protein CbbX
PfamA27U 15-183 -10.500 13  PF04910.9; O80734_ARATH/225-566; Transcriptional repressor TCF25
SCOP175 47-189 -8.240 15  d1hh8a_ a.118.8.1 (A:) Neutrophil cytosolic factor 2 (NCF-2, p67-phox) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 2-877 -14.300 VFG0337 (gi:16272928) iga - immunoglobin A1 protease [Haemophilus influenzae Rd] (VF0045)
91-631 -15.200 VFG0261 (gi:15676598) iga - IgA-specific serine endopeptidase [Neisseria meningitidis MC58 (serogroup B)] (VF0080)
564-876 -25.900 16  VFG2380 (gi:15611004) Rv3868 - hypothetical protein [Mycobacterium tuberculosis H37Rv] (VF0315)


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.