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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|15644635|ref|NP_206803.1| transcription antitermination protein NusB (HP0001) [Helicobacter pylori 26695] 138 COG0516 1-135 -70.700 27  [K] COG0781 Transcription termination factor
H.sapiens 4-117 -10.700 sp|Q8NE18|NSUN7_HUMAN Putative methyltransferase NSUN7 OS=Homo sapiens GN=NSUN7 PE=2 SV=4 (Range: 1-300)
39-134 -18.000 10  sp|P46087|NOP2_HUMAN Putative ribosomal RNA methyltransferase NOP2 OS=Homo sapiens GN=NOP2 PE=1 SV=2 (Range: 151-450)
HGM_OVER 5-137 -6.380 HGC00422 gi|163631722|dbj|BABG01004545.1|2.0 TMP00397;
JCSG0516 1-131 -29.800 18  SP1512A YP_194179.1 411796 Purified-2010-09-29
NEW_HUMAN_DOMAINS 55-111 -6.400 22  tr|E5RI81|E5RI81_HUMAN Uncharacterized protein OS=Homo sapiens PE=4 SV=1 (Range: 52-131)
PDB0516 1-138 -71.900 31  3r2d_A mol:protein length:149 N utilization substance protein B
PfamA30U 5-130 -73.400 24  PF01029.16; NUSB_DEHM1/6-132; NusB family
SCOP206 2-138 -70.900 28  d1tzva_ a.79.1.1 (A:) Antitermination factor NusB {Thermotoga maritima [TaxId: 2336]}
VFDB 1-138 -5.710 11  VFG001005(gi:31983568) (mxiC) type III secretion system gatekeeper MxiD [TTSS (VF0118)] [Shigella flexneri 2a str. 301]
2 gi|15644636|ref|NP_206804.1| 6,7-dimethyl-8-ribityllumazine synthase (HP0002) [Helicobacter pylori 26695] 156 COG0516 1-156 -92.800 48  [H] COG0054 Riboflavin synthase beta-chain
H.sapiens 8-136 -8.160 12  sp|Q9Y4L1|HYOU1_HUMAN(removed signalp:1-32) Hypoxia up-regulated protein 1 OS=Homo sapiens GN=HYOU1 PE=1 SV=1 (Range: 301-600)
HGM_OVER 77-145 -4.070 14  PB012386 gi|82541244|ref|XP_724876.1| blood-stage membrane protein Ag-1 [Plasmodium yoelii yoelii str. 17XNL]gi|23479680|gb|EAA16441.1| blood-stage membrane protein Ag-1 [Plasmodium yoelii yoelii]
JCSG0516 1-156 -97.300 41  TM1825 TM1825 283678 Purified-2001-12-11
NEW_HUMAN_DOMAINS 58-118 -5.130 18  sp|Q0P5Q8|FAM7A_HUMAN Protein FAM7A OS=Homo sapiens GN=FAM7A1 PE=1 SV=3 (Range: 1-69)
PDB0516 1-155 -97.900 48  1rvv_A mol:protein length:154 RIBOFLAVIN SYNTHASE
PfamA30U 13-152 -94.600 50  PF00885.17; R7PPI3_9FIRM/12-151; 6,7-dimethyl-8-ribityllumazine synthase
SCOP206 1-155 -97.600 50  d1nqua_ c.16.1.1 (A:) Lumazine synthase {Aquifex aeolicus [TaxId: 63363]}
VFDB 8-149 -5.210 14  VFG002197(gi:29375537) (bopD) sugar-binding transcriptional regulator, LacI family [BopD (VF0362)] [Enterococcus faecalis V583]
3 gi|15644637|ref|NP_206805.1| 2-dehydro-3-deoxyphosphooctonate aldolase (HP0003) [Helicobacter pylori 26695] 276 COG0516 2-276 -116.000 42  [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase
H.sapiens 5-276 -8.910 14  sp|Q9NR45|SIAS_HUMAN Sialic acid synthase OS=Homo sapiens GN=NANS PE=1 SV=2
HGM_OVER 13-140 -4.430 12  PB006791 A6TXD6_9CLOT/1-181 PB006791; Pfam-B_6791;
JCSG0516 7-276 -41.500 30  TM0343 TM0343 282218 PDB-2005-02-14
NEW_HUMAN_DOMAINS 198-256 -5.550 23  tr|F8W8T6|F8W8T6_HUMAN Uncharacterized protein OS=Homo sapiens GN=GSG1 PE=4 SV=1 (Range: 204-270)
PDB0516 1-276 -133.000 100  4z1a_A mol:protein length:276 2-dehydro-3-deoxyphosphooctonate aldolase
PfamA30U 2-243 -11.500 18  PF00793.18; AROG_HAEIN/32-347; DAHP synthetase I family
SCOP206 9-276 -122.000 51  d3e0ia_ c.1.10.4 (A:) 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8P synthase) {Aquifex aeolicus [TaxId: 63363]}
VFDB 2-276 -118.000 46  VFG011414(gi:17987133) (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M]
4 gi|15644638|ref|NP_206806.1| carbonic anhydrase (icfA) (HP0004) [Helicobacter pylori 26695] 221 COG0516 2-219 -99.100 23  [P] KOG1578 Predicted carbonic anhydrase involved in protection against oxidative damage
H.sapiens 25-102 -8.090 18  sp|P01215|GLHA_HUMAN(removed signalp:1-24) Glycoprotein hormones alpha chain OS=Homo sapiens GN=CGA PE=1 SV=1
HGM_OVER 92-174 -2.840 HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
JCSG0516 18-109 -8.030 15  YDR428C YDR428C 354901 PDB-2004-05-20
NEW_HUMAN_DOMAINS 37-76 -6.300 25  sp|Q5HYC2|K2026_HUMAN Uncharacterized protein KIAA2026 OS=Homo sapiens GN=KIAA2026 PE=2 SV=2 (Range: 1809-1944)
PDB0516 2-209 -101.000 28  1ekj_A mol:protein length:221 BETA-CARBONIC ANHYDRASE
PfamA30U 33-195 -86.000 26  PF00484.17; Q28W87_JANSC/42-203; Carbonic anhydrase
SCOP206 2-209 -101.000 28  d1ekja_ c.53.2.1 (A:) beta-carbonic anhydrase {Pea (Pisum sativum) [TaxId: 3888]}
VFDB 56-184 -5.480 11  VFG002236(gi:49476015) (virB7) 15-kDa antigen protein VirB7 [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]
5 gi|15644639|ref|NP_206807.1| orotidine 5'-phosphate decarboxylase (HP0005) [Helicobacter pylori 26695] 227 COG0516 2-227 -112.000 33  [F] COG0284 Orotidine-5`-phosphate decarboxylase
H.sapiens 2-226 -27.000 18  sp|P11172|PYR5_HUMAN Uridine 5`-monophosphate synthase OS=Homo sapiens GN=UMPS PE=1 SV=1
HGM_OVER 5-175 -3.460 12  HGC00921 gi|162841401|dbj|BABA01003308.1|3.0 TMP01242;
JCSG0516 1-227 -85.300 29  TM0332 TM0332 282207 PDB-2005-01-04
NEW_HUMAN_DOMAINS 42-172 -4.700 sp|Q9HCD6|TANC2_HUMAN Protein TANC2 OS=Homo sapiens GN=TANC2 PE=1 SV=3 (Range: 641-834)
PDB0516 2-227 -112.000 35  1dbt_A mol:protein length:239 OROTIDINE 5`-PHOSPHATE DECARBOXYLASE
PfamA30U 2-223 -110.000 34  PF00215.22; PYRF_STRP1/5-224; Orotidine 5`-phosphate decarboxylase / HUMPS family
SCOP206 1-227 -118.000 52  d3ru6a1 c.1.2.0 (A:1-227) automated matches {Campylobacter jejuni [TaxId: 192222]}
VFDB 1-210 -5.750 12  VFG043390(gi:15646189) (pdxJ) pyridoxine 5`-phosphate synthase [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
6 gi|15644640|ref|NP_206808.1| pantoate--beta-alanine ligase (HP0006) [Helicobacter pylori 26695] 276 COG0516 1-276 -119.000 39  [H] COG0414 Panthothenate synthetase
H.sapiens 119-226 -8.000 17  sp|Q5QNW6|H2B2F_HUMAN Histone H2B type 2-F OS=Homo sapiens GN=HIST2H2BF PE=1 SV=3
HGM_OVER 39-163 -3.830 13  PB002794 gi|86143885|ref|ZP_01062253.1| hypothetical protein MED217_03525 [Flavobacterium sp. MED217]gi|85829592|gb|EAQ48055.1| hypothetical protein MED217_03525 [Leeuwenhoekiella blandensis MED217]
JCSG0516 1-276 -127.000 42  TM1077 TM1077 282944 Purified-2001-12-12
NEW_HUMAN_DOMAINS 72-195 -5.490 17  sp|Q9H9T3|ELP3_HUMAN Elongator complex protein 3 OS=Homo sapiens GN=ELP3 PE=1 SV=2 (Range: 294-441)
PDB0516 1-276 -127.000 42  2ejc_A mol:protein length:280 Pantoate--beta-alanine ligase
PfamA30U 3-275 -126.000 38  PF02569.13; L0F3M1_DESDL/2-278; Pantoate-beta-alanine ligase
SCOP206 1-276 -125.000 40  d3mxta1 c.26.1.0 (A:1-282) automated matches {Campylobacter jejuni [TaxId: 192222]}
VFDB 19-164 -6.880 15  VFG000320(gi:15646084) (kdtB) lipopolysaccharide core biosynthesis protein [LPS (VF0056)] [Helicobacter pylori 26695]
7 gi|15646197|ref|NP_206811.1| outer membrane protein (HP0009) [Helicobacter pylori 26695] 634 COG0516 453-634 -9.630 13  [M] COG3637 Opacity protein and related surface antigens
H.sapiens 1-545 -8.300 sp|Q76KD6|SPERI_HUMAN Speriolin OS=Homo sapiens GN=SPATC1 PE=2 SV=2
HGM_OVER 459-576 -4.440 12  HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;
JCSG0516 4-632 -13.700 SP17586A YP_974743.1 412301 Selected-2009-11-12
283-634 -56.800 23  RH20376A NP_208292.1 416152 Selected-2009-12-04
NEW_HUMAN_DOMAINS 447-634 -5.110 15  tr|E9PPM1|E9PPM1_HUMAN Uncharacterized protein OS=Homo sapiens GN=TP53I11 PE=4 SV=1 (Range: 25-191)
PDB0516 1-460 -29.300 23  4o5j_A mol:protein length:461 Uncharacterized protein
463-634 -13.100 14  2lhf_A mol:protein length:179 Outer membrane protein H1
PfamA30U 412-634 -9.560 13  PF05736.9; PORF_PSEFL/1-186; OprF membrane domain
465-634 -59.600 38  PF01856.15; O26005_HELPY/59-248; Helicobacter outer membrane protein
SCOP206 436-632 -10.300 10  d3qraa_ f.4.1.0 (A:) automated matches {Yersinia pestis [TaxId: 632]}
VFDB 1-634 -114.000 100  VFG001142(gi:15646197) (hopZ) outer membrane protein adhesin [HopZ (VF0054)] [Helicobacter pylori 26695]
8 gi|15644643|ref|NP_206812.1| chaperonin GroEL (HP0010) [Helicobacter pylori 26695] 546 COG0516 1-539 -157.000 61  [O] COG0459 Chaperonin GroEL (HSP60 family)
H.sapiens 1-546 -145.000 53  sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochondrial OS=Homo sapiens GN=HSPD1 PE=1 SV=2
HGM_OVER 229-408 -4.500 12  PB007843 JCVI_PEP_1096682172521 /source_dna_id=JCVI_ORF_1096682172520 /offset=0 /translation_table=11 /length=152 /full_length=152
JCSG0516 1-534 -154.000 59  TM0506 TM0506 282379 Purified-2001-12-06
NEW_HUMAN_DOMAINS 58-128 -5.110 17  sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha OS=Homo sapiens GN=PI4KA PE=1 SV=3 (Range: 963-1052)
PDB0516 1-546 -156.000 60  1grl_A mol:protein length:548 GROEL (HSP60 CLASS)
PfamA30U 22-522 -29.800 17  PF00118.22; TCPB_DICDI/34-524; TCP-1/cpn60 chaperonin family
SCOP206 2-231 -71.600 44  d1kp8a1 a.129.1.1 (A:2-136,A:410-526) GroEL, E domain {Escherichia coli [TaxId: 562]}
190-375 -90.300 64  d3osxa1 c.8.5.1 (A:191-376) automated matches {Xenorhabdus nematophila [TaxId: 628]}
311-408 -38.200 46  d1kp8a3 d.56.1.1 (A:137-190,A:367-409) GroEL, I domain {Escherichia coli [TaxId: 562]}
VFDB 1-546 -158.000 62  VFG001855(gi:52840925) (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
9 gi|15644644|ref|NP_206813.1| co-chaperonin GroES (HP0011) [Helicobacter pylori 26695] 118 COG0516 1-90 -49.000 38  [O] COG0234 Co-chaperonin GroES (HSP10)
H.sapiens 1-91 -48.700 37  sp|P61604|CH10_HUMAN 10 kDa heat shock protein, mitochondrial OS=Homo sapiens GN=HSPE1 PE=1 SV=2
HGM_OVER 9-90 -4.480 13  PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;
JCSG0516 1-91 -54.000 40  TM0505 TM0505 282378 Crystal|NMR-2002-07-01
NEW_HUMAN_DOMAINS 6-93 -8.480 18  sp|Q9C0C9|UBE2O_HUMAN Ubiquitin-conjugating enzyme E2 O OS=Homo sapiens GN=UBE2O PE=1 SV=3 (Range: 116-311)
PDB0516 1-90 -52.400 47  4v4o_O mol:protein length:100 cpn10(GroES)
PfamA30U 3-87 -45.800 35  PF00166.19; B7PEU9_IXOSC/8-98; Chaperonin 10 Kd subunit
SCOP206 2-90 -50.700 38  d3nx6a_ b.35.1.0 (A:) automated matches {Xanthomonas oryzae [TaxId: 291331]}
VFDB 6-110 -6.760 12  VFG036974(gi:15677563) (mtrC) membrane fusion protein MtrC [MtrCDE (VF0451)] [Neisseria meningitidis MC58]
10 gi|15644645|ref|NP_206814.1| DNA primase (HP0012) [Helicobacter pylori 26695] 559 COG0516 1-558 -123.000 26  [L] COG0358 DNA primase (bacterial type)
H.sapiens 11-305 -33.600 16  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1 (Range: 1-300)
123-413 -17.200 12  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1 (Range: 151-450)
HGM_OVER 173-284 -2.610 13  HGC00593 gi|162858151|dbj|BABB01011554.1|1.0 TMP00709;
JCSG0516 1-558 -122.000 26  TM1452 TM1452 283310 Selected-2001-10-12
NEW_HUMAN_DOMAINS 21-91 -6.490 22  sp|A0PJM3|GORL_HUMAN Putative exonuclease GOR-like protein OS=Homo sapiens GN=REXO1L2P PE=5 SV=2 (Range: 322-408)
PDB0516 3-415 -104.000 31  2au3_A mol:protein length:407 DNA primase
423-559 -12.400 100  4ehs_A mol:protein length:155 DNA primase
PfamA30U 3-98 -56.500 45  PF01807.18; DNAG_PSEPK/6-101; CHC2 zinc finger
117-239 -51.100 35  PF08275.9; Q8F416_LEPIN/119-248; DNA primase catalytic core, N-terminal domain
249-334 -41.100 45  PF13155.4; Q8EPY5_OCEIH/263-348; Toprim-like
446-558 -9.570 15  PF08278.9; D3V2J4_XENBS/452-574; DNA primase DnaG DnaB-binding
SCOP206 1-98 -55.700 40  d1d0qa_ g.41.3.2 (A:) Zinc-binding domain of DNA primase {Bacillus stearothermophilus [TaxId: 1422]}
106-411 -81.100 29  d1dd9a_ e.13.1.1 (A:) DNA primase DnaG catalytic core {Escherichia coli [TaxId: 562]}
444-558 -9.850 15  d4im9a_ a.236.1.0 (A:) automated matches {Vibrio cholerae [TaxId: 345073]}
VFDB 95-351 -5.830 14  VFG045552(gi:52842203) (lpg1986) Dot/Icm type IV secretion system effector [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
11 gi|15644646|ref|NP_206815.1| hypothetical protein (HP0013) [Helicobacter pylori 26695] 350 COG0516 2-347 -56.100 16  [J] COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain
H.sapiens 2-347 -52.500 12  sp|O75648|MTU1_HUMAN Mitochondrial tRNA-specific 2-thiouridylase 1 OS=Homo sapiens GN=TRMU PE=1 SV=2
HGM_OVER 9-331 -3.060 10  PB162065 _Gut.Meta.Jp.0089312_ gi|162832207|dbj|BABA01012502.1||1 (- 0:1326~0 complete)
JCSG0516 2-349 -94.800 34  SP9715A ZP_02993753.1 410385 Purified-2010-09-29
NEW_HUMAN_DOMAINS 88-209 -5.880 tr|C9JCC5|C9JCC5_HUMAN Uncharacterized protein OS=Homo sapiens GN=IZUMO2 PE=4 SV=1 (Range: 21-192)
PDB0516 2-347 -59.200 15  2hma_A mol:protein length:376 Probable tRNA (5-methylaminomethyl-2-thiourid
PfamA30U 4-347 -58.800 13  PF03054.14; MNMA_CHLTR/3-350; tRNA methyl transferase
SCOP206 3-212 -17.500 24  d1vl2a1 c.26.2.1 (A:2-169) Argininosuccinate synthetase, N-terminal domain {Thermotoga maritima [TaxId: 2336]}
VFDB 2-320 -13.000 10  VFG012019(gi:15792639) (pseA) pseudaminic acid biosynthesis PseA protein [Pse5Ac7Ac, Pse5Ac7Am, Pse8OAc, Pse5Am7AcGlnAc (AI151)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
12 gi|15644647|ref|NP_206816.1| hypothetical protein (HP0014) [Helicobacter pylori 26695] 275 COG0516 2-254 -8.260 18  [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
H.sapiens 7-239 -8.930 14  sp|Q6P587|FAHD1_HUMAN Fumarylacetoacetate hydrolase domain-containing protein 1 OS=Homo sapiens GN=FAHD1 PE=1 SV=2
HGM_OVER 65-256 -3.700 12  PB001404 Q2S5L8_SALRD/1-256 PB001404; Pfam-B_1404;
JCSG0516 1-275 -134.000 100  RH20375A NP_206816.1 416151 Selected-2009-12-04
NEW_HUMAN_DOMAINS 163-230 -6.510 19  sp|Q8TB92|HMGC2_HUMAN Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2 OS=Homo sapiens GN=HMGCLL1 PE=2 SV=3 (Range: 1-73)
PDB0516 2-239 -9.500 14  3r6o_A mol:protein length:329 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase
PfamA30U 7-239 -10.300 12  PF01557.16; Q1LF48_CUPMC/58-257; Fumarylacetoacetate (FAA) hydrolase family
SCOP206 7-239 -9.790 19  d1gtta1 d.177.1.1 (A:1-213) 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpcE {Escherichia coli [TaxId: 562]}
VFDB 3-236 -4.200 10  VFG016005(gi:15597591) (pvdO) pyoverdine biosynthesis protein PvdO [pyoverdine (IA001)] [Pseudomonas aeruginosa PAO1]
13 gi|15644648|ref|NP_206817.1| hypothetical protein (HP0015) [Helicobacter pylori 26695] 93 COG0516 5-91 -9.780 17  [U] COG3838 Type IV secretory pathway, VirB2 components (pilins)
H.sapiens 1-87 -8.390 sp|Q9UPR3|SMG5_HUMAN Protein SMG5 OS=Homo sapiens GN=SMG5 PE=1 SV=3 (Range: 301-600)
HGM_OVER 22-79 -4.260 10  PB006154 _JGI.0331794_ 2004021056 [Human Gut Community Subject 7]
JCSG0516 1-41 -7.540 SP17982A NP_371336.1 413591 Selected-2009-11-12
NEW_HUMAN_DOMAINS 38-76 -6.430 23  sp|Q5SV97|CA170_HUMAN Uncharacterized protein C1orf170 OS=Homo sapiens GN=C1orf170 PE=2 SV=3 (Range: 613-696)
PDB0516 19-93 -6.200 12  1cii_A mol:protein length:602 COLICIN IA
PfamA30U 21-89 -13.400 18  PF04956.11; Q1M9P0_RHIL3/1-100; TrbC/VIRB2 family
SCOP206 36-71 -5.410 13  d2cqra1 a.4.1.3 (A:8-66) DnaJ homolog subfamily C member 1 {Human (Homo sapiens) [TaxId: 9606]}
VFDB 21-91 -14.100 11  VFG002231(gi:49476010) (virB2) type IV secretion system major pilin subunit VirB2 protein homolog [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]
14 gi|15644649|ref|NP_206818.1| hypothetical protein (HP0016) [Helicobacter pylori 26695] 87 COG0516 11-86 -16.400 [U] COG3702 Type IV secretory pathway, VirB3 components
H.sapiens 23-87 -10.000 17  sp|P31431|SDC4_HUMAN(removed signalp:1-18) Syndecan-4 OS=Homo sapiens GN=SDC4 PE=1 SV=2
HGM_OVER 12-87 -6.450 17  PB006154 _JGI.0331794_ 2004021056 [Human Gut Community Subject 7]
JCSG0516 1-28 -6.800 10  TM1487 TM1487 283344 Purified-2001-11-13
NEW_HUMAN_DOMAINS 28-85 -7.050 14  sp|Q6ZNA5|FRRS1_HUMAN Ferric-chelate reductase 1 OS=Homo sapiens GN=FRRS1 PE=2 SV=2 (Range: 502-569)
PDB0516 6-72 -7.330 17  1cii_A mol:protein length:602 COLICIN IA
PfamA30U 20-87 -7.150 16  PF05297.9; LMP1_EBVB9/1-386; Herpesvirus latent membrane protein 1 (LMP1)
SCOP206 14-79 -7.550 21  d1h6va2 c.3.1.5 (A:171-292) Mammalian thioredoxin reductase {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 7-82 -18.000 13  VFG002232(gi:49476011) (virB3) type IV secretion system virB3 protein homolog [VirB/VirD4 type IV secretion system (VF0369)] [Bartonella henselae str. Houston-1]
15 gi|15644650|ref|NP_206819.1| virB4 homolog (virB4) (HP0017) [Helicobacter pylori 26695] 787 COG0516 257-778 -53.500 15  [U] COG3451 Type IV secretory pathway, VirB4 components
H.sapiens 440-715 -9.240 15  sp|Q9UNQ0|ABCG2_HUMAN ATP-binding cassette sub-family G member 2 OS=Homo sapiens GN=ABCG2 PE=1 SV=3 (Range: 1-300)
HGM_OVER 11-201 -9.020 10  HGC00816 gi|163609134|dbj|BABG01026932.1|1.0 TMP01075;
JCSG0516 3-767 -66.200 13  SP14324A YP_001088362.1 410039 Selected-2009-11-12
NEW_HUMAN_DOMAINS 443-465 -6.870 13  sp|Q6P2S7|GNN_HUMAN Tetratricopeptide repeat protein GNN OS=Homo sapiens GN=GNN PE=2 SV=3 (Range: 217-335)
PDB0516 295-783 -19.200 12  4d2i_A mol:protein length:500 HERA
404-764 -30.700 14  4ag5_A mol:protein length:392 TYPE IV SECRETORY PATHWAY VIRB4 COMPONENTS-LI
PfamA30U 175-375 -50.900 14  PF03135.12; Q9ZE45_RICPR/194-399; CagE, TrbE, VirB family, component of type IV transporter system
416-744 -28.300 12  PF12846.5; Q833R2_ENTFA/443-804; AAA-like domain
436-779 -12.200 14  PF05872.10; Q2YMR9_BRUA2/13-501; Bacterial protein of unknown function (DUF853 topsan)
SCOP206 441-787 -17.500 16  d1e9ra_ c.37.1.11 (A:) Bacterial conjugative coupling protein TrwB {Escherichia coli [TaxId: 562]}
VFDB 1-787 -143.000 29  VFG001981(gi:32469876) (virB4) Type IV secretion system protein VirB4 [Type IV secretion system (VF0325)] [Campylobacter jejuni subsp. jejuni 81-176]
16 gi|15644651|ref|NP_206820.1| hypothetical protein (HP0018) [Helicobacter pylori 26695] 469 COG0516 1-469 -145.000 98  [S] COG3014 Uncharacterized protein conserved in bacteria
H.sapiens 15-277 -19.500 sp|O15294|OGT1_HUMAN UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens GN=OGT PE=1 SV=3 (Range: 1-300)
22-327 -19.200 10  sp|P50542|PEX5_HUMAN Peroxisomal targeting signal 1 receptor OS=Homo sapiens GN=PEX5 PE=1 SV=3 (Range: 301-600)
29-254 -23.000 sp|Q5T0N1|TTC18_HUMAN Tetratricopeptide repeat protein 18 OS=Homo sapiens GN=TTC18 PE=2 SV=2 (Range: 601-900)
HGM_OVER 1-113 -7.760 12  PB045072 _Gut.Meta.Jp.0111663_ gi|163310555|dbj|BABD01000145.1||3 (+ 1662:2028~0 complete)
JCSG0516 1-254 -31.100 17  SP11148B ZP_02433752.1 410301 Purified-2010-09-29
30-358 -20.200 MA2004C 13278497 399832 Selected-2008-12-22
NEW_HUMAN_DOMAINS 34-152 -13.600 sp|Q14674|ESPL1_HUMAN Separin OS=Homo sapiens GN=ESPL1 PE=1 SV=3 (Range: 717-845)
PDB0516 21-251 -25.300 10  3u4t_A mol:protein length:272 TPR repeat-containing protein
26-392 -17.700 1w3b_A mol:protein length:388 UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUC
PfamA30U 20-160 -19.900 11  PF12968.5; Q8KAL8_CHLTE/2-144; Domain of Unknown Function (DUF3856 topsan)
23-265 -19.100 PF04733.12; COPE2_ARATH/7-293; Coatomer epsilon subunit
26-469 -15.400 PF12569.6; A9SDC6_PHYPA/187-705; NMDA receptor-regulated protein 1
SCOP206 22-394 -18.100 d1fcha_ a.118.8.1 (A:) Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor) {Human (Homo sapiens) [TaxId: 9606]}
24-258 -23.300 10  d1xnfa_ a.118.8.1 (A:) Lipoprotein NlpI {Escherichia coli [TaxId: 562]}
VFDB 1-255 -28.600 11  VFG042869(gi:52841776) (pilF) type IV pilus biogenesis protein PilF [type IV pili (AI111)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
20-357 -12.400 VFG000423(gi:16763113) (vexE) Vi polysaccharide export protein VexE [Vi antigen (VF0101)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18]
17 gi|15644652|ref|NP_206821.1| chemotaxis protein (cheV) (HP0019) [Helicobacter pylori 26695] 321 COG0516 1-198 -63.000 24  [NT] COG0835 Chemotaxis signal transduction protein
198-321 -23.800 20  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
H.sapiens 197-321 -21.200 12  sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2 (Range: 1-300)
HGM_OVER 195-287 -3.430 18  PB001572 gi|163816107|ref|ZP_02207475.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]gi|158448527|gb|EDP25522.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]
JCSG0516 9-321 -98.200 22  GD10678B RER070207001006 388606 Selected-2007-09-21
NEW_HUMAN_DOMAINS 195-319 -23.500 13  sp|Q9NX45|SOLH2_HUMAN Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 OS=Homo sapiens GN=SOHLH2 PE=2 SV=2 (Range: 1-196)
PDB0516 12-180 -39.000 18  1k0s_A mol:protein length:151 CHEMOTAXIS PROTEIN CHEW
196-321 -37.100 24  1m5t_A mol:protein length:124 cell division response regulator DivK
PfamA30U 27-173 -11.300 11  PF01584.17; Q8XQ78_RALSO/559-691; CheW-like domain
199-305 -27.600 24  PF00072.22; RSSB_ECOLI/10-121; Response regulator receiver domain
SCOP206 18-175 -37.200 19  d4jpbw_ b.40.7.1 (W:) automated matches {Thermotoga maritima [TaxId: 243274]}
196-321 -36.600 24  d1mb3a_ c.23.1.1 (A:) Cell division response regulator DivK {Caulobacter crescentus [TaxId: 155892]}
VFDB 1-321 -120.000 100  VFG043364(gi:15644652) (cheV1) chemotaxis coupling protein CheV1 [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
18 gi|15644653|ref|NP_206822.1| carboxynorspermidine decarboxylase (nspC) (HP0020) [Helicobacter pylori 26695] 405 COG0516 5-405 -22.100 15  [E] COG0019 Diaminopimelate decarboxylase
H.sapiens 8-388 -18.300 15  sp|Q96A70|ADC_HUMAN Arginine decarboxylase OS=Homo sapiens GN=ADC PE=2 SV=1
HGM_OVER 60-289 -3.570 HGC00166 gi|163579340|dbj|BABE01005762.1|1.0 TMP00473;
JCSG0516 1-405 -147.000 100  XB5406A 2313093 358544 Purified-2005-03-29
NEW_HUMAN_DOMAINS 175-304 -4.950 11  sp|O95866|G6B_HUMAN Protein G6b OS=Homo sapiens GN=G6B PE=1 SV=1 (Range: 18-142)
PDB0516 2-405 -133.000 47  3n29_A mol:protein length:418 Carboxynorspermidine decarboxylase
PfamA30U 268-384 -12.400 19  PF00278.20; R9SMY8_9EURY/294-398; Pyridoxal-dependent decarboxylase, C-terminal sheet domain
SCOP206 15-266 -22.200 14  d1knwa2 c.1.6.1 (A:32-278) Diaminopimelate decarboxylase LysA {Escherichia coli [TaxId: 562]}
245-395 -18.000 19  d1twia1 b.49.2.3 (A:15-49,A:314-448) Diaminopimelate decarboxylase LysA {Methanococcus jannaschii [TaxId: 2190]}
VFDB 237-378 -4.930 17  VFG011399(gi:17987115) (fabZ) (3R)-hydroxymyristoyl ACP dehydratase [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M]
19 gi|15644654|ref|NP_206823.1| lipid A 1-phosphatase (HP0021) [Helicobacter pylori 26695] 190 COG0516 23-190 -47.600 14  [S] KOG4268 Uncharacterized conserved protein containing PAP2 domain
H.sapiens 23-190 -46.500 14  sp|Q8NBV4|PPAC3_HUMAN Probable lipid phosphate phosphatase PPAPDC3 OS=Homo sapiens GN=PPAPDC3 PE=2 SV=1
HGM_OVER 40-188 -4.150 PB032242 Q8FLW6_COREF/1-257 PB032242; Pfam-B_32242;
JCSG0516 37-189 -53.000 17  C.JNH21312E ZP_01995411.1 430135 Selected-2013-07-30
NEW_HUMAN_DOMAINS 120-167 -6.920 tr|E7ENG5|E7ENG5_HUMAN Uncharacterized protein OS=Homo sapiens GN=G6PC PE=4 SV=1 (Range: 83-178)
PDB0516 8-189 -34.400 15  4px7_A mol:protein length:262 Phosphatidylglycerophosphatase
PfamA30U 79-189 -32.100 18  PF01569.19; F2G969_ALTMD/101-223; PAP2 superfamily
SCOP206 64-181 -26.500 16  d1d2ta_ a.111.1.1 (A:) Bacterial acid phosphatase {Escherichia blattae [TaxId: 563]}
VFDB 45-189 -45.100 14  VFG011439(gi:17987495) (lpxE) phosphatidylglycerophosphatase B [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M]
20 gi|15644655|ref|NP_206824.1| lipid A phosphoethanolamine transferase (HP0022) [Helicobacter pylori 26695] 521 COG0516 2-521 -120.000 25  [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase
H.sapiens 216-513 -17.000 14  sp|Q6UWY0|ARSK_HUMAN(removed signalp:1-22) Arylsulfatase K OS=Homo sapiens GN=ARSK PE=2 SV=1
HGM_OVER 244-355 -3.620 HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
JCSG0516 1-518 -22.100 12  TT16481A NP_743993.1 404410 Selected-2009-08-14
NEW_HUMAN_DOMAINS 403-482 -5.890 18  sp|Q6UWP7|LCLT1_HUMAN Lysocardiolipin acyltransferase 1 OS=Homo sapiens GN=LCLAT1 PE=1 SV=1 (Range: 253-360)
PDB0516 207-521 -98.000 32  4kav_A mol:protein length:335 YhbX/YhjW/YijP/YjdB family protein
PfamA30U 57-203 -39.300 15  PF08019.10; E0SIY3_DICD3/59-211; Domain of unknown function (DUF1705 topsan)
191-499 -11.600 PF02995.15; Q9VIP6_DROME/56-555; Protein of unknown function (DUF229 topsan)
SCOP206 220-514 -11.300 11  d1auka_ c.76.1.2 (A:) Arylsulfatase A {Human (Homo sapiens) [TaxId: 9606]}
VFDB 12-521 -116.000 31  VFG043392(gi:218561919) (eptC) phosphoethanolamine transferase [Pse5Ac7Ac, Pse5Ac7Am, Pse8OAc, Pse5Am7AcGlnAc (AI151)] [Campylobacter jejuni subsp. jejuni NCTC 11168]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Slabinski L, Jaroszewski L, Rychlewski L, Wilson IA, Lesley SA, Godzik A. XtalPred: a web server for prediction of protein crystallizability. Bioinformatics. 2007 Dec 15;23(24):3403-5. Epub 2007 Oct 5.