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# Query Length Result vs. Range Score %id Covered by template(s)
1 VFG000851(gi:2576413) (aafA) major fimbrial subunit of aggregative adherence fimbria II AafA [AAFs (VF0214)] [Escherichia coli str. 042] 160 COG0516 17-158 -9.290 13  [S] COG5430 Uncharacterized secreted protein
H.sapiens 36-154 -7.260 16  sp|Q5JPE7|NOMO2_HUMAN(removed signalp:1-31) Nodal modulator 2 OS=Homo sapiens GN=NOMO2 PE=1 SV=1 (Range: 451-750)
HGM_OVER 9-153 -7.040 PB017610 Q11T14_CYTH3/22-188 PB017610; Pfam-B_17610;
JCSG0516 1-158 -15.400 12  TT7209A NP_744509.1 404835 Selected-2009-08-14
NEW_HUMAN_DOMAINS 13-64 -6.060 17  sp|O14841|OPLA_HUMAN 5-oxoprolinase OS=Homo sapiens GN=OPLAH PE=1 SV=3 (Range: 663-733)
PDB0516 36-160 -71.800 100  2mpv_A mol:protein length:145 Major fimbrial subunit of aggregative adheren
PfamA30U 22-160 -13.900 13  PF04619.10; O07093_ECOLX/22-160; Dr-family adhesin
SCOP206 22-160 -14.000 16  d2bcma_ b.2.3.0 (A:) automated matches {Escherichia coli [TaxId: 562]}
VFDB 1-157 -67.500 23  VFG000847(gi:531400) (aggA) fimbrial major subunit [AAFs (VF0214)] [Escherichia coli 17-2]
2 VFG000854(gi:4689214) (aafB) invasin homolog AafB [AAFs (VF0214)] [Escherichia coli str. 042] 146 COG0516 1-137 -9.100 10  [R] COG5633 Predicted periplasmic lipoprotein
H.sapiens 23-146 -7.000 sp|Q3ZCW2|LEGL_HUMAN Galectin-related protein OS=Homo sapiens GN=GRP PE=1 SV=2
HGM_OVER 1-139 -9.370 18  PB083081 gi|160890648|ref|ZP_02071651.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]gi|156859647|gb|EDO53078.1| hypothetical protein BACUNI_03093 [Bacteroides uniformis ATCC 8492]
JCSG0516 1-146 -12.600 SP13439A ZP_01961388.1 406999 Purified-2010-09-29
NEW_HUMAN_DOMAINS 20-138 -6.750 12  sp|Q9C0C9|UBE2O_HUMAN Ubiquitin-conjugating enzyme E2 O OS=Homo sapiens GN=UBE2O PE=1 SV=3 (Range: 534-709)
PDB0516 19-146 -68.900 96  4or1_A mol:protein length:155 Invasin homolog AafB, Major fimbrial subunit
PfamA30U 2-144 -22.400 12  PF06443.9; Q47405_ECOLX/2-166; SEF14-like adhesin
34-139 -56.700 24  PF05775.10; Q7CR56_SALTY/44-148; Enterobacteria AfaD invasin protein
SCOP206 24-146 -62.900 56  d2axwa1 b.2.3.2 (A:1-121) Invasin AfaD {Escherichia coli [TaxId: 562]}
VFDB 1-143 -73.700 57  VFG000856(gi:22001088) (agg3B) invasin protein [AAFs (VF0214)] [Escherichia coli 55989]
3 VFG000853(gi:4689215) (aafC) aggregative adherence fimbria II usher protein AafC [AAFs (VF0214)] [Escherichia coli str. 042] 856 COG0516 7-855 -189.000 33  [NU] COG3188 P pilus assembly protein, porin PapC
H.sapiens 264-395 -6.520 13  sp|Q6JVE9|LCN8_HUMAN(removed signalp:1-25) Epididymal-specific lipocalin-8 OS=Homo sapiens GN=LCN8 PE=2 SV=1
HGM_OVER 687-813 -3.550 15  PB001572 gi|163816107|ref|ZP_02207475.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]gi|158448527|gb|EDP25522.1| hypothetical protein COPEUT_02291 [Coprococcus eutactus ATCC 27759]
JCSG0516 54-856 -9.960 10  SP14815A NP_253179.1 413182 Selected-2009-11-12
NEW_HUMAN_DOMAINS 173-776 -5.660 sp|Q86XX4|FRAS1_HUMAN Extracellular matrix protein FRAS1 OS=Homo sapiens GN=FRAS1 PE=2 SV=1 (Range: 3191-3823)
PDB0516 31-855 -185.000 34  3rfz_B mol:protein length:843 Outer membrane usher protein, type 1 fimbrial
PfamA30U 33-187 -50.400 37  PF13954.4; A7MEY2_CROS8/8-155; PapC N-terminal domain
204-764 -123.000 30  PF00577.18; A8AF47_CITK8/198-751; Outer membrane usher protein
773-839 -27.400 35  PF13953.4; A6TGZ4_KLEP7/658-724; PapC C-terminal domain
SCOP206 31-174 -46.000 39  d4b0ma_ b.167.1.0 (A:) automated matches {Yersinia pestis [TaxId: 632]}
VFDB 3-856 -203.000 82  VFG042425(gi:218921798) (afaC-I) usher AfaC [Afimbrial adhesin, AFA-I, mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863]
4 VFG000852(gi:4596718) (aafD) chaperone protein AafD [AAFs (VF0214)] [Escherichia coli str. 042] 241 COG0516 6-240 -81.000 19  [NU] COG3121 P pilus assembly protein, chaperone PapD
H.sapiens 31-231 -9.870 13  sp|Q6ZU64|CC108_HUMAN Coiled-coil domain-containing protein 108 OS=Homo sapiens GN=CCDC108 PE=2 SV=2 (Range: 601-900)
33-192 -10.000 12  sp|Q4G0P3|HYDIN_HUMAN Hydrocephalus-inducing protein homolog OS=Homo sapiens GN=HYDIN PE=1 SV=2 (Range: 1051-1350)
HGM_OVER 43-172 -5.700 15  HGC00803 gi|163280588|dbj|BABD01030100.1|2.0 TMP01051;
JCSG0516 8-240 -48.400 15  SP17313A YP_001713378.1 406449 Selected-2009-11-12
NEW_HUMAN_DOMAINS 79-189 -6.600 17  sp|Q92562|FIG4_HUMAN Polyphosphoinositide phosphatase OS=Homo sapiens GN=FIG4 PE=1 SV=1 (Range: 597-715)
PDB0516 10-241 -100.000 64  4djm_A mol:protein length:239 DraB
PfamA30U 31-159 -63.100 30  PF00345.18; YADV_ECOLI/27-151; Pili and flagellar-assembly chaperone, PapD N-terminal domain
181-238 -26.200 37  PF02753.15; I0DNL8_PROSM/205-264; Pili assembly chaperone PapD, C-terminal domain
SCOP206 30-159 -66.600 44  d4ay0a1 b.1.11.0 (A:13-130) automated matches {Yersinia pestis [TaxId: 632]}
160-240 -38.500 40  d4ay0a2 b.7.2.0 (A:131-217) automated matches {Yersinia pestis [TaxId: 632]}
VFDB 6-241 -97.700 26  VFG000455(gi:16766925) (lpfB) long polar fimbrial chaperone protein LpfB [Lpf (VF0105)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
5 VFG000865(gi:387604907) (aap/aspU) Dispersin [Dispersin (VF0215)] [Escherichia coli O44:H18 042] 116 COG0516 1-82 -7.140 12  [S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein
H.sapiens 2-116 -7.500 11  sp|Q9P2R6|RERE_HUMAN Arginine-glutamic acid dipeptide repeats protein OS=Homo sapiens GN=RERE PE=1 SV=2 (Range: 151-450)
HGM_OVER 1-116 -8.610 17  PB009671 Q5LCM2_BACFN/1-111 PB009671; Pfam-B_9671;
JCSG0516 1-35 -10.400 17  SP16857A ZP_02037157.1 407190 Purified-2010-09-29
1-102 -9.960 14  SP13691H YP_213000.1 407830 Purified-2010-09-29
NEW_HUMAN_DOMAINS 29-61 -5.560 24  sp|Q96BN6|F149B_HUMAN Protein FAM149B1 OS=Homo sapiens GN=FAM149B1 PE=2 SV=2 (Range: 219-293)
PDB0516 22-115 -46.100 100  2jvu_A mol:protein length:104 DISPERSIN
PfamA30U 1-102 -8.600 13  PF12389.6; Q8ENF4_OCEIH/2-208; Camelysin metallo-endopeptidase
SCOP206 16-114 -7.600 11  d2b5xa1 c.47.1.10 (A:1-143) thiol:disulfide oxidoreductase YkuV {Bacillus subtilis [TaxId: 1423]}
VFDB 1-69 -8.350 18  VFG000435(gi:17233483) (pefA) plasmid-encoded fimbriae major subunit PefA [Pef (VF0104)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
6 VFG044024(gi:169639785) (ACA60977) alpha-toxin [alpha-toxin (septicum) (VF0416)] [Clostridium septicum str. NH2] 443 COG0516 163-280 -6.880 [S] COG4719 Uncharacterized protein conserved in bacteria
H.sapiens 142-268 -8.240 11  sp|P19823|ITIH2_HUMAN(removed signalp:1-18) Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens GN=ITIH2 PE=1 SV=2 (Range: 1-300)
HGM_OVER 127-283 -7.940 10  PB004718 Q5LIA4_BACFN/1-189 PB004718; Pfam-B_4718;
JCSG0516 142-324 -35.600 12  SP17047A ZP_02073170.1 409566 Purified-2010-09-29
NEW_HUMAN_DOMAINS 142-287 -7.200 sp|Q9NVH1|DJC11_HUMAN DnaJ homolog subfamily C member 11 OS=Homo sapiens GN=DNAJC11 PE=1 SV=2 (Range: 128-409)
PDB0516 46-428 -73.900 21  1pre_A mol:protein length:470 PROAEROLYSIN
PfamA30U 55-406 -71.200 18  PF01117.18; A7SFW2_NEMVE/192-549; Aerolysin toxin
SCOP206 46-428 -75.600 21  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 2-420 -37.500 11  VFG002291(gi:209947607) (ext) epsilon-toxin [epsilon-toxin (VF0380)] [Clostridium perfringens str. NCTC 8533B4D]
7 VFG000110(gi:15641470) (ace) accessory cholera enterotoxin [Ace (VF0130)] [Vibrio cholerae O1 biovar El Tor str. N16961] 97 COG0516 1-97 -7.830 10  [A] KOG2253 U1 snRNP complex, subunit SNU71 and related PWI-motif proteins
H.sapiens 29-93 -8.280 sp|Q01831|XPC_HUMAN DNA repair protein complementing XP-C cells OS=Homo sapiens GN=XPC PE=1 SV=4 (Range: 1-300)
HGM_OVER 43-93 -4.470 11  PB027778 Q5LHJ0_BACFN/1-110 PB027778; Pfam-B_27778;
JCSG0516 40-90 -5.640 SP18048A NP_372942.2 413657 Purified-2010-11-20
NEW_HUMAN_DOMAINS 40-93 -5.730 18  sp|Q96P71|NECA3_HUMAN N-terminal EF-hand calcium-binding protein 3 OS=Homo sapiens GN=NECAB3 PE=1 SV=2 (Range: 89-148)
PDB0516 46-97 -6.030 12  1ej5_A mol:protein length:107 WISKOTT-ALDRICH SYNDROME PROTEIN
PfamA30U 34-93 -11.000 13  PF10734.7; Q9JRT4_NEIMB/3-82; Protein of unknown function (DUF2523 topsan)
SCOP206 46-97 -6.030 12  d1ej5a_ a.68.1.1 (A:) Wiscott-Aldrich syndrome protein, WASP, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
VFDB 4-97 -6.350 VFG041330(gi:52842615) (lem23) Dot/Icm type IV secretion system effector Lem23 [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
8 VFG002166(gi:29375675) (ace) collagen adhesin protein [Ace (VF0355)] [Enterococcus faecalis V583] 674 COG0516 171-592 -10.200 10  [TZ] KOG4035 Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover
284-649 -13.000 [Z] KOG3756 Pinin (desmosome-associated protein)
312-622 -15.000 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
H.sapiens 298-594 -13.200 10  sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding protein OS=Homo sapiens GN=TNKS1BP1 PE=1 SV=4 (Range: 1-300)
332-623 -18.100 12  sp|Q9P2P1|NYNRI_HUMAN Protein NYNRIN OS=Homo sapiens GN=NYNRIN PE=1 SV=3 (Range: 451-750)
356-659 -15.600 10  sp|Q9Y3S1|WNK2_HUMAN Serine/threonine-protein kinase WNK2 OS=Homo sapiens GN=WNK2 PE=1 SV=4 (Range: 751-1050)
HGM_OVER 1-315 -6.740 PB064361 Q64PJ4_BACFR/1-580 PB064361; Pfam-B_64361;
JCSG0516 26-648 -29.200 SP17586C NP_439153.1 411588 Selected-2009-11-12
NEW_HUMAN_DOMAINS 450-594 -6.780 12  sp|P18583|SON_HUMAN Protein SON OS=Homo sapiens GN=SON PE=1 SV=4 (Range: 606-751)
PDB0516 27-367 -55.800 98  2z1p_A mol:protein length:348 Collagen adhesin protein
328-572 -13.500 4cwu_T mol:protein length:368 CORE-CAPSID BRIDGING PROTEIN
PfamA30U 61-297 -31.200 12  PF11766.6; G8BJ60_CANPC/58-305; Cell-wall agglutinin N-terminal ligand-sugar binding
279-649 -11.600 10  PF03154.13; R9PXW0_RAT/567-1558; Atrophin-1 family
382-577 -12.300 10  PF15708.3; G7PVG9_MACFA/1-223; Proline-rich protein family 20
382-646 -12.200 PF11725.6; Q887C9_PSESM/17-1794; Pathogenicity factor
SCOP206 34-162 -21.900 17  d1n67a1 b.2.3.4 (A:229-369) Clumping factor A {Staphylococcus aureus [TaxId: 1280]}
173-318 -26.000 100  d2okma_ b.2.3.0 (A:) automated matches {Enterococcus faecalis [TaxId: 1351]}
VFDB 1-672 -42.400 17  VFG043518(gi:29134931) (acm) collagen adhesin precursor Acm [Acm (VF0419)] [Enterococcus faecium str. TX2555]
9 VFG000103(gi:15640861) (acfA) accessory colonization factor AcfA [ACF (VF0127)] [Vibrio cholerae O1 biovar El Tor str. N16961] 215 COG0516 1-215 -51.000 14  [M] COG3637 Opacity protein and related surface antigens
H.sapiens 43-215 -7.020 sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens GN=VDAC2 PE=1 SV=2
HGM_OVER 1-52 -8.710 11  PB045072 _Gut.Meta.Jp.0111663_ gi|163310555|dbj|BABD01000145.1||3 (+ 1662:2028~0 complete)
JCSG0516 1-215 -64.200 11  SP19450B YP_096648.1 412277 Purified-2010-09-29
NEW_HUMAN_DOMAINS 4-22 -5.620 sp|Q9Y2G1|MRF_HUMAN Myelin gene regulatory factor OS=Homo sapiens GN=MRF PE=1 SV=3 (Range: 758-829)
PDB0516 4-215 -75.500 15  2k0l_A mol:protein length:216 Outer membrane protein A
PfamA30U 1-215 -76.400 12  PF06316.9; Q9LA63_9CAUD/1-199; Enterobacterial Ail/Lom protein
SCOP206 14-215 -64.400 18  d1qjpa_ f.4.1.1 (A:) Outer membrane protein A (OMPA) transmembrane domain {Escherichia coli [TaxId: 562]}
VFDB 1-215 -73.500 14  VFG000354(gi:16123096) (ail) attachment invasion locus protein [Ail (VF0132)] [Yersinia pestis CO92]
10 VFG000104(gi:15640857) (acfB) accessory colonization factor AcfB [ACF (VF0127)] [Vibrio cholerae O1 biovar El Tor str. N16961] 626 COG0516 1-346 -38.000 12  [T] COG2770 FOG: HAMP domain
294-626 -64.400 25  [NT] COG0840 Methyl-accepting chemotaxis protein
H.sapiens 4-279 -30.700 13  sp|Q5VU97|CAHD1_HUMAN(removed signalp:1-37) VWFA and cache domain-containing protein 1 OS=Homo sapiens GN=CACHD1 PE=1 SV=2 (Range: 601-900)
112-381 -24.900 11  sp|Q9NY47|CA2D2_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-2 OS=Homo sapiens GN=CACNA2D2 PE=1 SV=1 (Range: 451-750)
318-624 -17.600 10  sp|Q9Y4G6|TLN2_HUMAN Talin-2 OS=Homo sapiens GN=TLN2 PE=1 SV=4 (Range: 1351-1650)
HGM_OVER 393-589 -5.850 PB162020 _JGI.0344610_ 2004040329 [Human Gut Community Subject 8]
JCSG0516 1-626 -75.500 21  TM0023 TM0023 281904 Purified-2001-08-24
NEW_HUMAN_DOMAINS 431-614 -6.920 sp|Q15111|PLCL1_HUMAN Inactive phospholipase C-like protein 1 OS=Homo sapiens GN=PLCL1 PE=1 SV=3 (Range: 874-1059)
PDB0516 26-277 -40.200 23  5ave_A mol:protein length:257 Methyl-accepting chemotaxis (MCP) signaling d
294-626 -43.100 26  3zx6_A mol:protein length:341 HAMP, METHYL-ACCEPTING CHEMOTAXIS PROTEIN I
331-625 -49.300 22  2ch7_A mol:protein length:309 METHYL-ACCEPTING CHEMOTAXIS PROTEIN
PfamA30U 32-257 -12.400 PF02743.16; D3EMN3_GEOS4/45-297; Cache domain
99-235 -13.500 16  PF17155.2; A8AHH5_CITK8/31-304; Gammaproteobacterial periplasmic sensor domain
297-625 -23.100 PF06109.11; K7JEL9_NASVI/32-340; Haemolysin E (HlyE)
364-606 -43.200 11  PF03532.11; O50963_BORBU/3-255; OMS28 porin
SCOP206 51-187 -9.390 16  d2basa2 d.110.6.2 (A:263-407) Hypothetical protein YkuI, C-terminal domain {Bacillus subtilis [TaxId: 1423]}
VFDB 3-626 -98.400 22  VFG000088(gi:15640842) (tcpI) toxin co-regulated pilus biosynthesis protein I [TCP (VF0126)] [Vibrio cholerae O1 biovar El Tor str. N16961]
11 VFG000105(gi:15640858) (acfC) accessory colonization factor AcfC [ACF (VF0127)] [Vibrio cholerae O1 biovar El Tor str. N16961] 256 COG0516 4-256 -85.100 50  [R] COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain
H.sapiens 26-254 -6.700 12  sp|Q92841|DDX17_HUMAN Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens GN=DDX17 PE=1 SV=1 (Range: 151-450)
HGM_OVER 1-123 -5.310 HGC01056 gi|162659434|dbj|BAAX01000171.1|2.0 TMP01455;
JCSG0516 7-256 -97.000 49  SP5482A NP_287515.1 411011 Selected-2009-11-12
NEW_HUMAN_DOMAINS 97-242 -5.250 15  sp|Q12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens GN=BPTF PE=1 SV=3 (Range: 1831-1972)
PDB0516 7-256 -103.000 93  4jb7_A mol:protein length:256 Accessory colonization factor AcfC
PfamA30U 4-254 -12.400 11  PF02030.13; Y045_MYCGE/1-482; Hypothetical lipoprotein (MG045 family)
39-247 -40.800 16  PF01547.23; CYSP_ECOLI/33-278; Bacterial extracellular solute-binding protein
SCOP206 39-254 -40.100 21  d1sbpa_ c.94.1.1 (A:) Sulphate-binding protein {Salmonella typhimurium [TaxId: 90371]}
VFDB 7-256 -97.000 49  VFG000839(gi:15801498) (paa) outer membrane adhesin Paa [Paa (VF0194)] [Escherichia coli O157:H7 str. EDL933]
12 VFG000106(gi:15640862) (acfD) accessory colonization factor AcfD [ACF (VF0127)] [Vibrio cholerae O1 biovar El Tor str. N16961] 1520 COG0516 1-720 -11.200 [Q] COG3321 Polyketide synthase modules and related proteins
H.sapiens 448-725 -13.400 14  sp|A6NFQ2|F115C_HUMAN Protein FAM115C OS=Homo sapiens GN=FAM115C PE=2 SV=2 (Range: 151-450)
466-839 -13.200 11  sp|Q9Y4C2|F115A_HUMAN Protein FAM115A OS=Homo sapiens GN=FAM115A PE=1 SV=3 (Range: 1-300)
1004-1297 -21.300 18  sp|Q9Y4C2|F115A_HUMAN Protein FAM115A OS=Homo sapiens GN=FAM115A PE=1 SV=3 (Range: 451-750)
1148-1482 -39.900 22  sp|Q9Y4C2|F115A_HUMAN Protein FAM115A OS=Homo sapiens GN=FAM115A PE=1 SV=3 (Range: 601-900)
1304-1518 -35.700 17  sp|A6NFQ2|F115C_HUMAN Protein FAM115C OS=Homo sapiens GN=FAM115C PE=2 SV=2 (Range: 751-919)
HGM_OVER 1-537 -6.900 PB064361 Q64PJ4_BACFR/1-580 PB064361; Pfam-B_64361;
JCSG0516 1-706 -12.200 SP14267E ZP_02043803.1 406535 Selected-2009-11-12
337-1520 -54.400 12  SP19122A NP_249263.1 413334 Selected-2009-11-12
NEW_HUMAN_DOMAINS 1414-1520 -18.200 20  sp|Q9Y4C2|F115A_HUMAN Protein FAM115A OS=Homo sapiens GN=FAM115A PE=1 SV=3 (Range: 842-921)
PDB0516 1-728 -11.000 12  2vz8_A mol:protein length:2512 FATTY ACID SYNTHASE
60-701 -12.000 11  2wan_A mol:protein length:921 PULLULANASE
1048-1518 -45.100 18  4fca_A mol:protein length:525 Conserved domain protein
PfamA30U 392-566 -63.100 64  PF13322.4; Q87GE0_VIBPA/378-553; Domain of unknown function (DUF4092 topsan)
1072-1471 -40.700 23  PF13402.4; TCAF_DANRE/515-886; Peptidase M60, enhancin and enhancin-like
SCOP206 54-721 -9.510 12  d1twfa_ e.29.1.2 (A:) RBP1 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 5-724 -12.900 10  VFG002548(gi:53720398) (wcbR) capsular polysaccharide biosynthesis fatty acid synthase [Capsule I (VF0436)] [Burkholderia pseudomallei K96243]
69-726 -13.900 10  VFG043508(gi:29374740) (fss1) Enterococcus faecalis surface protein Fss1, fibrinogen binding protein [Fibrinogen binding protein (AI271)] [Enterococcus faecalis V583]
13 VFG043518(gi:29134931) (acm) collagen adhesin precursor Acm [Acm (VF0419)] [Enterococcus faecium str. TX2555] 721 COG0516 28-721 -19.400 13  [M] COG4932 Predicted outer membrane protein
H.sapiens 1-133 -10.900 10  sp|Q9BY50|SC11C_HUMAN Signal peptidase complex catalytic subunit SEC11C OS=Homo sapiens GN=SEC11C PE=1 SV=3
339-627 -15.600 12  sp|Q5JPE7|NOMO2_HUMAN(removed signalp:1-31) Nodal modulator 2 OS=Homo sapiens GN=NOMO2 PE=1 SV=1 (Range: 1-300)
HGM_OVER 1-118 -9.720 11  HGC01056 gi|162659434|dbj|BAAX01000171.1|2.0 TMP01455;
1-208 -9.510 10  PB048631 gi|160885545|ref|ZP_02066548.1| hypothetical protein BACOVA_03545 [Bacteroides ovatus ATCC 8483]gi|156109167|gb|EDO10912.1| hypothetical protein BACOVA_03545 [Bacteroides ovatus ATCC 8483]
JCSG0516 23-720 -21.300 10  SP17977A NP_373026.1 413581 Selected-2009-11-12
NEW_HUMAN_DOMAINS 1-126 -5.710 sp|Q9NPR9|GP108_HUMAN Protein GPR108 OS=Homo sapiens GN=GPR108 PE=2 SV=3 (Range: 1-143)
PDB0516 23-438 -45.800 13  3is1_X mol:protein length:446 Uro-adherence factor A
26-368 -54.700 20  2z1p_A mol:protein length:348 Collagen adhesin protein
28-336 -64.200 44  2f68_X mol:protein length:313 Collagen adhesin
431-711 -61.400 24  1d2p_A mol:protein length:373 COLLAGEN ADHESIN
PfamA30U 1-143 -11.800 11  PF16341.3; R5U6I7_9BACE/2-141; Domain of unknown function (DUF4971 topsan)
60-298 -36.300 PF11766.6; G8BJ60_CANPC/58-305; Cell-wall agglutinin N-terminal ligand-sugar binding
531-647 -26.300 12  PF16570.3; Q8DYR6_STRA5/379-514; Gram-positive pilin backbone subunit 3, Cna-B-like domain
534-615 -34.000 42  PF05738.11; F7V5S1_CLOSS/768-856; Cna protein B-type domain
SCOP206 31-159 -29.500 17  d1n67a1 b.2.3.4 (A:229-369) Clumping factor A {Staphylococcus aureus [TaxId: 1280]}
170-320 -23.300 48  d1amxa_ b.2.3.1 (A:) Collagen-binding domain of adhesin {Staphylococcus aureus [TaxId: 1280]}
331-440 -16.900 17  d3rkpa3 b.3.5.0 (A:409-515) automated matches {Bacillus cereus [TaxId: 226900]}
530-619 -41.600 50  d1d2oa1 b.3.5.1 (A:535-624) B repeat unit of collagen binding surface protein (cna) {Staphylococcus aureus [TaxId: 1280]}
VFDB 1-711 -70.500 27  VFG001291(gi:21284341) (cna) collagen adhesin precursor [CNA (VF0005)] [Staphylococcus aureus subsp. aureus MW2]
14 VFG005770(gi:22536832) (acpC) acyl carrier protein AcpC [Beta-hemolysin/cytolysin (CVF171)] [Streptococcus agalactiae 2603V/R] 101 COG0516 16-96 -35.600 21  [IQ] COG0236 Acyl carrier protein
H.sapiens 13-94 -24.900 24  sp|O14561|ACPM_HUMAN Acyl carrier protein, mitochondrial OS=Homo sapiens GN=NDUFAB1 PE=1 SV=3
HGM_OVER 38-92 -3.050 PB053138 Q73Q90_TREDE/1-298 PB053138; Pfam-B_53138;
JCSG0516 6-95 -41.800 35  FM11900A YP_298135.1 378261 Purified-2007-07-30
NEW_HUMAN_DOMAINS 42-94 -10.900 18  sp|O60673|DPOLZ_HUMAN DNA polymerase zeta catalytic subunit OS=Homo sapiens GN=REV3L PE=1 SV=2 (Range: 1620-1692)
PDB0516 12-96 -39.600 21  2l4b_A mol:protein length:88 Acyl carrier protein
PfamA30U 12-101 -35.200 14  PF14573.4; B9Q5Z8_TOXGO/144-239; Acyl-carrier
SCOP206 15-96 -38.700 22  d2l4ba1 a.28.1.0 (A:6-88) automated matches {Anaplasma phagocytophilum [TaxId: 212042]}
VFDB 14-94 -36.800 28  VFG011430(gi:17987758) (acpXL) acyl carrier protein [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M]
15 VFG011429(gi:17987394) (acpXL) acyl carrier protein [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M] 93 COG0516 3-79 -42.900 27  [IQ] COG0236 Acyl carrier protein
H.sapiens 1-76 -31.600 25  sp|O14561|ACPM_HUMAN Acyl carrier protein, mitochondrial OS=Homo sapiens GN=NDUFAB1 PE=1 SV=3
HGM_OVER 2-65 -3.110 17  HGC00509 gi|162658693|dbj|BAAX01000912.1|3.0 TMP00561;
JCSG0516 1-78 -44.400 32  TM0662 TM0662 282534 Purified-2001-02-22
NEW_HUMAN_DOMAINS 1-63 -5.830 12  sp|Q12767|K0195_HUMAN Uncharacterized protein KIAA0195 OS=Homo sapiens GN=KIAA0195 PE=1 SV=1 (Range: 369-435)
PDB0516 1-93 -51.600 79  2kw2_A mol:protein length:101 Specialized acyl carrier protein
PfamA30U 1-85 -42.200 11  PF14573.4; B9Q5Z8_TOXGO/144-239; Acyl-carrier
SCOP206 2-78 -43.500 24  d1t8ka_ a.28.1.1 (A:) Acyl carrier protein {Escherichia coli [TaxId: 562]}
VFDB 1-78 -44.800 32  VFG011430(gi:17987758) (acpXL) acyl carrier protein [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M]
16 VFG011430(gi:17987758) (acpXL) acyl carrier protein [LPS (CVF383)] [Brucella melitensis bv. 1 str. 16M] 78 COG0516 3-78 -49.400 48  [IQ] COG0236 Acyl carrier protein
H.sapiens 1-76 -32.500 36  sp|O14561|ACPM_HUMAN Acyl carrier protein, mitochondrial OS=Homo sapiens GN=NDUFAB1 PE=1 SV=3
HGM_OVER 1-76 -2.630 11  PB007147 Q11UU2_CYTH3/1-245 PB007147; Pfam-B_7147;
JCSG0516 1-78 -50.800 53  TM0662 TM0662 282534 Purified-2001-02-22
NEW_HUMAN_DOMAINS 3-66 -6.100 18  sp|Q14562|DHX8_HUMAN ATP-dependent RNA helicase DHX8 OS=Homo sapiens GN=DHX8 PE=1 SV=1 (Range: 22-101)
PDB0516 1-78 -52.600 100  2n57_A mol:protein length:78 Acyl carrier protein
PfamA30U 1-78 -44.500 26  PF14573.4; B9Q5Z8_TOXGO/144-239; Acyl-carrier
SCOP206 2-78 -51.200 61  d1t8ka_ a.28.1.1 (A:) Acyl carrier protein {Escherichia coli [TaxId: 562]}
VFDB 1-77 -45.800 23  VFG002445(gi:53722548) (bapB) acyl carrier protein [Bsa T3SS (VF0428)] [Burkholderia pseudomallei K96243]
17 VFG000068(gi:16802250) (actA) actin-assembly inducing protein precursor [ActA (VF0066)] [Listeria monocytogenes EGD-e] 639 COG0516 1-371 -12.000 10  [S] KOG4502 Predicted membrane protein
3-332 -15.700 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
323-633 -11.200 [R] KOG0231 Junctional membrane complex protein Junctophilin and related MORN repeat proteins
H.sapiens 3-325 -16.200 10  sp|Q8NC44|F134A_HUMAN Protein FAM134A OS=Homo sapiens GN=FAM134A PE=1 SV=3
3-356 -9.510 sp|O60320|F1891_HUMAN Protein FAM189A1 OS=Homo sapiens GN=FAM189A1 PE=2 SV=4
489-634 -9.670 10  sp|Q9HDC5|JPH1_HUMAN Junctophilin-1 OS=Homo sapiens GN=JPH1 PE=1 SV=2 (Range: 451-661)
521-639 -10.100 14  sp|Q86YL7|PDPN_HUMAN(removed signalp:1-22) Podoplanin OS=Homo sapiens GN=PDPN PE=1 SV=3
HGM_OVER 3-107 -8.250 14  HGC01056 gi|162659434|dbj|BAAX01000171.1|2.0 TMP01455;
JCSG0516 23-424 -17.800 11  SP17586C NP_439153.1 411588 Selected-2009-11-12
405-639 -9.650 11  EL13177O YP_809644.1 423511 Selected-2011-05-25
479-639 -13.200 SP2600AD YP_794564.1 411897 Selected-2009-11-12
NEW_HUMAN_DOMAINS 612-639 -7.360 18  sp|Q9Y2G1|MRF_HUMAN Myelin gene regulatory factor OS=Homo sapiens GN=MRF PE=1 SV=3 (Range: 758-829)
PDB0516 605-638 -8.890 23  2llm_A mol:protein length:43 Amyloid beta A4 protein
PfamA30U 7-639 -163.000 100  PF05058.10; ACTA_LISMO/7-639; ActA Protein
SCOP206 604-639 -7.100 16  d3j9tr2 f.17.1.1 (R:82-160) V-type proton ATPase subunit c {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 23-424 -17.800 11  VFG000337(gi:16272928) (iga1) immunoglobin A1 protease [IgA1 protease (VF0045)] [Haemophilus influenzae Rd KW20]
29-612 -10.600 VFG000261(gi:15676598) (iga) IgA-specific serine endopeptidase [IgA1 protease (VF0080)] [Neisseria meningitidis MC58]
18 VFG002420(gi:21281752) (adsA) Adenosine synthase A [AdsA (VF0422)] [Streptococcus pyogenes MGAS315] 772 COG0516 108-631 -66.700 19  [F] COG0737 5`-nucleotidase/2`,3`-cyclic phosphodiesterase and related esterases
141-737 -14.000 12  [L] KOG2310 DNA repair exonuclease MRE11
H.sapiens 117-422 -11.100 11  sp|Q9BRF8|CPPED_HUMAN Calcineurin-like phosphoesterase domain-containing protein 1 OS=Homo sapiens GN=CPPED1 PE=1 SV=3
147-653 -94.600 26  sp|P21589|5NTD_HUMAN(removed signalp:1-26) 5`-nucleotidase OS=Homo sapiens GN=NT5E PE=1 SV=1
HGM_OVER 198-434 -2.330 PB022815 A4DEQ0_LISMO/1-452 PB022815; Pfam-B_22815;
JCSG0516 52-378 -10.200 11  SP16761I ZP_02038738.1 407154 Selected-2009-11-12
110-772 -91.000 18  SP18790A YP_001271626.1 411934 Selected-2009-11-12
131-645 -99.200 26  TM1878 TM1878 283730 Purified-2001-12-06
NEW_HUMAN_DOMAINS 546-598 -3.310 11  sp|Q14956|GPNMB_HUMAN Transmembrane glycoprotein NMB OS=Homo sapiens GN=GPNMB PE=1 SV=2 (Range: 168-249)
PDB0516 77-527 -10.700 13  4fbk_A mol:protein length:472 DNA repair and telomere maintenance protein n
117-647 -103.000 25  1ush_A mol:protein length:550 5`-NUCLEOTIDASE
PfamA30U 142-395 -15.000 10  PF14582.4; E4U4F7_OCEP5/1-237; Metallophosphoesterase, calcineurin superfamily
150-464 -12.400 10  PF09587.8; Q1GMM5_RUEST/3-314; Bacterial capsule synthesis protein PGA_cap
435-610 -51.500 29  PF02872.16; H9JWY4_BOMMO/1512-1686; 5`-nucleotidase, C-terminal domain
SCOP206 142-432 -67.000 27  d1hp1a2 d.159.1.2 (A:26-362) 5`-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain {Escherichia coli [TaxId: 562]}
433-648 -57.200 33  d2z1aa1 d.114.1.1 (A:330-534) 5`-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain {Thermus thermophilus [TaxId: 274]}
VFDB 122-417 -15.100 16  VFG000680(gi:6470207) (capA) CapA, required for Poly-gamma-glutamate transport [Capsule (VF0141)] [Bacillus anthracis]
19 VFG042423(gi:218921796) (afaA) fimbrial major subunit AfaA [Afimbrial adhesin, AFA-I, mannose-resistant adhesin (AI010)] [Escherichia coli O25b:H4 str. FV9863] 101 COG0516 23-81 -7.200 18  [TQ] COG2508 Regulator of polyketide synthase expression
H.sapiens 36-74 -6.500 17  sp|Q8N3X6|LCORL_HUMAN Ligand-dependent nuclear receptor corepressor-like protein OS=Homo sapiens GN=LCORL PE=2 SV=4 (Range: 451-602)
HGM_OVER 10-101 -4.130 11  HGC01024 gi|162869036|dbj|BABB01000971.1|4.0 TMP01399;
JCSG0516 23-78 -8.090 12  TT10262A NP_822594.1 403881 Selected-2009-08-14
NEW_HUMAN_DOMAINS 16-101 -5.230 12  sp|A6NN90|CB081_HUMAN Uncharacterized protein C2orf81 OS=Homo sapiens GN=C2orf81 PE=2 SV=2 (Range: 32-137)
PDB0516 1-100 -49.400 36  3m8j_A mol:protein length:111 FocB protein
PfamA30U 1-89 -47.200 40  PF03333.11; A0A0E1L7V1_ECOLX/3-96; Adhesin biosynthesis transcription regulatory protein
SCOP206 34-83 -7.680 16  d1oyia_ a.4.5.19 (A:) dsRNA-binding protein E3 (E3L) {Vaccinia virus [TaxId: 10245]}
VFDB 1-101 -57.600 99  VFG000942(gi:13241931) (draA) cytoplamic protein DraA [Dr adhesins (VF0223)] [Escherichia coli O75:K5:H- str. IH11128]
20 VFG042441(gi:13236678) (afaA-VIII) AfaA-VIII [Afimbrial adhesin, AfaE-VIII (AI015)] [Escherichia coli str. 239 KH 89] 127 COG0516 1-79 -7.780 13  [K] COG1758 DNA-directed RNA polymerase, subunit K/omega
H.sapiens 12-127 -7.680 16  sp|Q9H0A8|COMD4_HUMAN COMM domain-containing protein 4 OS=Homo sapiens GN=COMMD4 PE=1 SV=1
HGM_OVER 32-123 -5.360 HGC01024 gi|162869036|dbj|BABB01000971.1|4.0 TMP01399;
JCSG0516 37-95 -7.570 11  TT10262A NP_822594.1 403881 Selected-2009-08-14
NEW_HUMAN_DOMAINS 33-127 -6.380 16  tr|B4DVM5|B4DVM5_HUMAN Uncharacterized protein OS=Homo sapiens GN=WDR24 PE=2 SV=1 (Range: 391-511)
PDB0516 11-115 -48.500 35  3m8j_A mol:protein length:111 FocB protein
PfamA30U 11-103 -47.100 38  PF03333.11; A0A0E1L7V1_ECOLX/3-96; Adhesin biosynthesis transcription regulatory protein
SCOP206 1-92 -8.350 18  d1zj8a2 d.58.36.1 (A:10-161) Sulfite reductase NirA {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 11-109 -48.900 38  VFG000881 (papB) regulatory protein PapB [P fimbriae (VF0220)] [Escherichia coli CFT073]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ye Y, Godzik A. Comparative analysis of protein domain organization. Genome Res. 2004 Mar;14(3):343-53.