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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|108885075|ref|NP_072661.2| DNA polymerase III, beta subunit (MG_001) [Mycoplasma genitalium G37] 380 COG1214 1-380 -89.000 19  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
H.sapiens 140-378 -9.710 11  sp|P12004|PCNA_HUMAN Proliferating cell nuclear antigen OS=Homo sapiens GN=PCNA PE=1 SV=1
HGM_OVER 65-272 -2.140 PB038401 Q8RFH0_FUSNN/1-210 PB038401; Pfam-B_38401;
JCSG1214 1-380 -101.000 20  XB5465A NP_344555.1 358603 PDB-2005-08-31
NEW_HUMAN_DOMAINS 305-368 -4.070 sp|Q8NEB7|ACRBP_HUMAN Acrosin-binding protein OS=Homo sapiens GN=ACRBP PE=2 SV=1 (Range: 403-472)
PDB1214 1-380 -102.000 21  4tr6_A mol:protein length:380 DNA polymerase III subunit beta
PfamA27U 1-121 -48.200 20  PF00712.14; DPO3B_BACSU/1-127; DNA polymerase III beta subunit, N-terminal domain
135-256 -38.500 13  PF02767.11; DPO3B_PROMI/129-244; DNA polymerase III beta subunit, central domain
258-380 -53.800 29  PF02768.10; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP175 1-121 -47.600 18  d1ok7a1 d.131.1.1 (A:1-122) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
129-257 -43.400 14  d1ok7a2 d.131.1.1 (A:123-244) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
258-380 -51.700 23  d1vpka3 d.131.1.1 (A:244-366) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
VFDB 246-333 -4.560 VFG1878 (gi:52842095) lspL - general secretion pathway protein L [Legionella pneumophila Philadelphia 1] (VF0154)
2 gi|108885076|ref|NP_072662.2| DnaJ domain-containing protein (MG_002) [Mycoplasma genitalium G37] 310 COG1214 2-309 -98.600 17  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
H.sapiens 2-310 -91.500 19  sp|Q9UBS4|DJB11_HUMAN(removed signalp:1-22) DnaJ homolog subfamily B member 11 OS=Homo sapiens GN=DNAJB11 PE=1 SV=1
HGM_OVER 9-63 -5.960 21  PB002794 gi|86143885|ref|ZP_01062253.1| hypothetical protein MED217_03525 [Flavobacterium sp. MED217]gi|85829592|gb|EAQ48055.1| hypothetical protein MED217_03525 [Leeuwenhoekiella blandensis MED217]
JCSG1214 2-308 -100.000 19  TM0849 TM0849 282719 Selected-2001-10-12
NEW_HUMAN_DOMAINS 1-59 -7.900 13  sp|Q9UBC1|IKBL1_HUMAN NF-kappa-B inhibitor-like protein 1 OS=Homo sapiens GN=NFKBIL1 PE=1 SV=1 (Range: 294-381)
PDB1214 2-309 -72.200 16  3lz8_A mol:protein length:329 Putative chaperone DnaJ
PfamA27U 2-61 -38.600 46  PF00226.26; Q22028_CAEEL/17-79; DnaJ domain
150-218 -20.700 13  PF00684.14; DNAJ1_CORGL/147-211; DnaJ central domain
SCOP175 2-70 -43.000 39  d1xbla_ a.2.3.1 (A:) DnaJ chaperone, N-terminal (J) domain {Escherichia coli [TaxId: 562]}
2-103 -37.800 19  d1gh6a_ a.2.3.1 (A:) Large T antigen, the N-terminal J domain {Simian virus 40, Sv40 [TaxId: 10633]}
135-223 -25.100 11  d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}
187-266 -14.800 13  d1nlta1 b.4.1.1 (A:110-138,A:213-257) Mitochondrial protein import protein mas5 (Hsp40, Ydj1), C-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 11-60 -6.150 22  VFG2034 (gi:13508191) hmw3 - cytadherence accessory protein HMW3 [Mycoplasma pneumoniae M129] (VF0330)
3 gi|12044853|ref|NP_072663.1| DNA gyrase subunit B (MG_003) [Mycoplasma genitalium G37] 650 COG1214 3-650 -151.000 47  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
H.sapiens 2-247 -56.100 24  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 1-300)
87-408 -63.600 19  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 151-450)
263-552 -77.200 26  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 301-600)
411-650 -62.400 27  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 451-750)
HGM_OVER 472-639 -3.760 20  HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;
JCSG1214 8-650 -202.000 48  TM0833 TM0833 282703 Purified-2005-04-05
NEW_HUMAN_DOMAINS 512-584 -6.310 27  sp|Q9H799|CE042_HUMAN Uncharacterized protein C5orf42 OS=Homo sapiens GN=C5orf42 PE=2 SV=3 (Range: 1-96)
PDB1214 2-649 -185.000 46  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA27U 228-408 -77.600 38  PF00204.20; Q9R3E4_ACISP/115-285; DNA gyrase B
548-643 -27.300 22  PF16898; F5HDJ4.1/657-784; C-terminal associated domain of TOPRIM
576-639 -45.800 57  PF00986.16; Q6MRR8_BDEBA/731-795; DNA gyrase B subunit, carboxyl terminus
SCOP175 7-227 -89.800 47  d1ei1a2 d.122.1.2 (A:2-220) DNA gyrase B {Escherichia coli [TaxId: 562]}
228-409 -79.300 34  d1ei1a1 d.14.1.3 (A:221-392) DNA gyrase B {Escherichia coli [TaxId: 562]}
423-640 -25.900 28  d1bjta_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 24-547 -8.520 11  VFG1568 (gi:23954252) orf34 - hypothetical protein [Escherichia coli 536]
4 gi|12044854|ref|NP_072664.1| DNA gyrase subunit A (MG_004) [Mycoplasma genitalium G37] 836 COG1214 16-836 -205.000 39  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
H.sapiens 2-226 -42.900 28  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 601-900)
86-392 -59.000 23  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 751-1050)
239-491 -31.200 14  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 901-1200)
HGM_OVER 409-496 -3.270 PB045072 _Gut.Meta.Jp.0111663_ gi|163310555|dbj|BABD01000145.1||3 (+ 1662:2028~0 complete)
JCSG1214 18-817 -202.000 41  TM1084 TM1084 282951 Purified-2001-04-24
NEW_HUMAN_DOMAINS 49-195 -5.010 20  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1 (Range: 373-516)
PDB1214 1-500 -147.000 53  2xco_A mol:protein length:726 DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A
42-756 -138.000 32  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
512-835 -69.200 32  3uc1_A mol:protein length:327 DNA gyrase subunit A
PfamA27U 44-474 -89.300 29  PF00521.15; A1ZXC5_9BACT/29-447; DNA gyrase/topoisomerase IV, subunit A
620-665 -13.000 37  PF03989.8; GYRA_HAEIN/641-686; DNA gyrase C-terminal domain, beta-propeller
SCOP175 42-498 -133.000 52  d1ab4a_ e.11.1.1 (A:) DNA Gyrase A {Escherichia coli [TaxId: 562]}
514-815 -64.200 27  d1suua_ b.68.10.1 (A:) DNA gyrase A C-terminal domain {Lyme disease spirochete (Borrelia burgdorferi) [TaxId: 139]}
VFDB 53-644 -7.210 13  VFG0079 (gi:16802278) clpC - endopeptidase Clp ATP-binding chain C [Listeria monocytogenes (serovar 1/2a) EGD-e] (VF0072)
5 gi|12044855|ref|NP_072665.1| seryl-tRNA synthetase (MG_005) [Mycoplasma genitalium G37] 417 COG1214 1-416 -126.000 42  [J] COG0172 Seryl-tRNA synthetase
H.sapiens 1-416 -115.000 27  sp|Q9NP81|SYSM_HUMAN Seryl-tRNA synthetase, mitochondrial OS=Homo sapiens GN=SARS2 PE=1 SV=1
HGM_OVER 255-361 -3.610 15  PB031792 gi|154174791|ref|YP_001409041.1| flavodoxin family protein [Campylobacter curvus 525.92]gi|112804021|gb|EAU01365.1| flavodoxin family protein [Campylobacter curvus 525.92]
JCSG1214 1-416 -131.000 41  TM1379 TM1379 283240 Crystal|NMR-2004-06-10
NEW_HUMAN_DOMAINS 26-104 -5.350 tr|B5MDG7|B5MDG7_HUMAN Uncharacterized protein OS=Homo sapiens GN=HMG20B PE=4 SV=2 (Range: 199-286)
PDB1214 1-417 -133.000 43  2dq3_A mol:protein length:425 Seryl-tRNA synthetase
PfamA27U 1-104 -36.600 24  PF02403.17; Q8GE42_HELMO/1-107; Seryl-tRNA synthetase N-terminal domain
169-338 -96.100 48  PF00587.20; SYS_BACSU/173-344; tRNA synthetase class II core domain (G, H, P, S and T)
SCOP175 1-109 -38.100 22  d1seta1 a.2.7.1 (A:1-110) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
113-417 -113.000 37  d1seta2 d.104.1.1 (A:111-421) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
VFDB 4-106 -5.340 13  VFG1777 (gi:15088619) orf8 - unknown [Yersinia enterocolitica A127]
6 gi|12044856|ref|NP_072666.1| thymidylate kinase (MG_006) [Mycoplasma genitalium G37] 210 COG1214 3-209 -90.000 31  [F] COG0125 Thymidylate kinase
H.sapiens 1-207 -65.600 20  sp|P23919|KTHY_HUMAN Thymidylate kinase OS=Homo sapiens GN=DTYMK PE=1 SV=4
HGM_OVER 4-105 -3.580 10  PB040621 Q8A865_BACTN/1-132 PB040621; Pfam-B_40621;
JCSG1214 5-206 -83.600 28  TM1099 TM1099 282965 Purified-2003-11-26
NEW_HUMAN_DOMAINS 44-123 -5.800 sp|Q4ZG55|GREB1_HUMAN Protein GREB1 OS=Homo sapiens GN=GREB1 PE=2 SV=1 (Range: 72-212)
PDB1214 1-204 -89.400 29  3v9p_A mol:protein length:227 Thymidylate kinase
PfamA27U 9-197 -86.700 33  PF02223.12; KTHY_BACSU/8-199; Thymidylate kinase
SCOP175 3-207 -84.200 30  d4tmka_ c.37.1.1 (A:) Thymidylate kinase {Escherichia coli [TaxId: 562]}
VFDB 2-202 -9.760 14  VFG1988 (gi:15792733) Cj1415c - possible adenylylsulfate kinase [Campylobacter jejuni NCTC 11168] (VF0323)
7 gi|12044857|ref|NP_072667.1| DNA polymerase III subunit delta' (MG_007) [Mycoplasma genitalium G37] 254 COG1214 2-254 -75.700 16  [L] COG2812 DNA polymerase III, gamma/tau subunits
H.sapiens 2-245 -32.700 11  sp|Q9Y230|RUVB2_HUMAN RuvB-like 2 OS=Homo sapiens GN=RUVBL2 PE=1 SV=3
HGM_OVER 73-201 -3.930 HGC00962 gi|162759780|dbj|BAAZ01005693.1|3.0 TMP01305;
JCSG1214 2-254 -81.200 15  TM0686 TM0686 282556 Purified-2001-02-28
NEW_HUMAN_DOMAINS 87-251 -5.450 10  sp|Q5BKU6|YP026_HUMAN Putative uncharacterized protein LOC641298 OS=Homo sapiens PE=5 SV=2 (Range: 403-569)
PDB1214 2-205 -82.800 20  1njf_A mol:protein length:250 DNA polymerase III subunit gamma
2-253 -71.000 17  3glf_B mol:protein length:395 DNA polymerase III subunit tau
PfamA27U 2-144 -73.500 23  PF13177.1; B3XQR6_LACRE/12-172; DNA polymerase III, delta subunit
2-187 -32.300 12  PF06068.8; Q9GZH2_CAEEL/17-408; TIP49 C-terminus
5-251 -13.700 10  PF03215.10; RAD24_YEAST/58-575; Rad17 cell cycle checkpoint protein
SCOP175 2-205 -82.900 20  d1njfa_ c.37.1.20 (A:) delta prime subunit of DNA polymerase III, N-domain {Escherichia coli [TaxId: 562]}
VFDB 1-238 -13.300 VFG2401 (gi:15608935) Rv1798 - hypothetical protein [Mycobacterium tuberculosis H37Rv] (VF0402)
8 gi|12044858|ref|NP_072668.1| tRNA modification GTPase TrmE (MG_008) [Mycoplasma genitalium G37] 442 COG1214 1-442 -118.000 28  [R] COG0486 Predicted GTPase
H.sapiens 3-442 -112.000 25  sp|Q969Y2|GTPB3_HUMAN tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens GN=GTPBP3 PE=2 SV=2
HGM_OVER 88-141 -3.550 HGC00573 gi|163306732|dbj|BABD01003960.1|2.0 TMP00669;
JCSG1214 1-438 -30.200 10  TT0527A YP_322606.1 404770 Selected-2009-08-14
89-433 -33.400 15  TT0445B YP_291340.1 404181 Selected-2009-08-14
NEW_HUMAN_DOMAINS 191-334 -4.850 11  sp|Q8IVG5|SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like OS=Homo sapiens GN=SAMD9L PE=1 SV=2 (Range: 687-863)
PDB1214 1-442 -126.000 27  3gee_A mol:protein length:476 tRNA modification GTPase mnmE
PfamA27U 6-121 -52.100 27  PF10396.4; MNME_PSEA6/12-126; GTP-binding protein TrmE N-terminus
178-429 -12.400 13  PF05049.8; Q9DCE9_MOUSE/50-412; Interferon-inducible GTPase (IIGP)
219-332 -38.100 26  PF01926.18; DER_CHLCV/3-119; 50S ribosome-binding GTPase
219-438 -12.700 13  PF04670.7; Q9VHJ4_DROME/4-230; Gtr1/RagA G protein conserved region
368-439 -24.800 18  PF12631.2; B7IBI3_ACIB5/331-403; Catalytic cysteine-containing C-terminus of GTPase, MnmE
SCOP175 5-121 -60.100 42  d1xzpa3 d.250.1.2 (A:1-117) TrmE formyl-THF-binding domain {Thermotoga maritima [TaxId: 2336]}
122-442 -39.300 24  d1xzpa1 a.24.25.1 (A:118-211,A:372-450) TrmE connector domain {Thermotoga maritima [TaxId: 2336]}
217-362 -55.500 32  d2gj8a1 c.37.1.8 (A:216-376) Probable tRNA modification GTPase TrmE (MnmE), G domain {Escherichia coli [TaxId: 562]}
VFDB 188-435 -29.200 17  VFG0654 (gi:24114254) SF2990 - orf, conserved hypothetical protein [Shigella flexneri (serotype 2a) 301]
9 gi|12044859|ref|NP_072669.1| TatD family deoxyribonuclease (MG_009) [Mycoplasma genitalium G37] 262 COG1214 1-261 -103.000 27  [L] COG0084 Mg-dependent DNase
H.sapiens 1-261 -95.300 23  sp|Q17R31|TATD3_HUMAN Putative deoxyribonuclease TATDN3 OS=Homo sapiens GN=TATDN3 PE=1 SV=1
HGM_OVER 74-250 -4.130 10  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
JCSG1214 3-261 -104.000 31  TM0667 TM0667 282539 PDB-2002-07-09
NEW_HUMAN_DOMAINS 177-260 -5.950 sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens GN=NID1 PE=1 SV=3 (Range: 52-175)
PDB1214 2-261 -103.000 31  2gzx_A mol:protein length:265 putative TatD related DNase
PfamA27U 4-260 -94.700 29  PF01026.16; Y454_HAEIN/4-256; TatD related DNase
SCOP175 1-261 -103.000 31  d1j6oa_ c.1.9.12 (A:) Hypothetical protein TM0667 {Thermotoga maritima [TaxId: 2336]}
VFDB 3-260 -7.550 10  VFG1351 (gi:22537332) cpsB - capsular polysaccharide biosynthesis protein CpsB [Streptococcus agalactiae 2603V/R] (VF0274)
10 gi|12044860|ref|NP_072670.1| DNA primase-related protein (MG_010) [Mycoplasma genitalium G37] 218 COG1214 2-217 -63.200 17  [L] COG0358 DNA primase (bacterial type)
H.sapiens 25-216 -32.400 16  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1 (Range: 151-450)
HGM_OVER 4-206 -4.150 10  HGC00921 gi|162841401|dbj|BABA01003308.1|3.0 TMP01242;
JCSG1214 5-217 -62.400 19  TM1452 TM1452 283310 Selected-2001-10-12
NEW_HUMAN_DOMAINS 24-217 -5.860 15  sp|Q9Y4D8|K0614_HUMAN Probable E3 ubiquitin-protein ligase C12orf51 OS=Homo sapiens GN=C12orf51 PE=1 SV=5 (Range: 2192-2433)
PDB1214 1-216 -78.000 18  4e2k_A mol:protein length:329 DNA primase
PfamA27U 1-106 -33.900 15  PF08275.6; Q64P92_BACFR/123-254; DNA primase catalytic core, N-terminal domain
114-201 -39.600 25  PF13155.1; C5EJG0_9FIRM/258-343; Toprim-like
SCOP175 2-217 -72.800 19  d1dd9a_ e.13.1.1 (A:) DNA primase DnaG catalytic core {Escherichia coli [TaxId: 562]}
VFDB 120-201 -6.740 12  VFG1590 (gi:23954273) orf56 - hypothetical protein [Escherichia coli 536]
11 gi|12044861|ref|NP_072671.1| hypothetical protein (MG_011) [Mycoplasma genitalium G37] 287 COG1214 1-282 -32.300 12  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
H.sapiens 8-285 -76.200 15  sp|Q8IXN7|RIMKA_HUMAN Ribosomal protein S6 modification-like protein A OS=Homo sapiens GN=RIMKLA PE=2 SV=2
HGM_OVER 181-285 -2.930 PB004996 Q5NNS6_ZYMMO/1-150 PB004996; Pfam-B_4996;
JCSG1214 9-287 -70.900 16  PU9803J YP_001095162.1 381332 Crystal|NMR-2007-12-14
NEW_HUMAN_DOMAINS 79-191 -6.230 sp|Q66K74|MAP1S_HUMAN Microtubule-associated protein 1S OS=Homo sapiens GN=MAP1S PE=1 SV=2 (Range: 328-458)
PDB1214 9-279 -82.100 17  3vpb_A mol:protein length:282 Putative acetylornithine deacetylase
PfamA27U 1-275 -42.600 11  PF05770.6; Q9AYJ2_ORYSJ/16-320; Inositol 1, 3, 4-trisphosphate 5/6-kinase
94-273 -66.800 19  PF08443.6; RIMK_HAEIN/105-293; RimK-like ATP-grasp domain
SCOP175 11-96 -18.500 14  d1uc8a1 c.30.1.6 (A:1-88) Lysine biosynthesis enzyme LysX, N-terminal domain {Thermus thermophilus [TaxId: 274]}
97-278 -65.400 16  d1uc8a2 d.142.1.7 (A:89-280) Lysine biosynthesis enzyme LysX ATP-binding domain {Thermus thermophilus [TaxId: 274]}
VFDB 178-280 -6.310 10  VFG2249 (gi:49476210) trwN - trwN protein [Bartonella henselae Houston-1] (VF0372)
12 gi|12044862|ref|NP_072672.1| alpha-L-glutamate ligase (MG_012) [Mycoplasma genitalium G37] 287 COG1214 6-287 -30.100 19  [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)
H.sapiens 2-287 -77.800 22  sp|Q8IXN7|RIMKA_HUMAN Ribosomal protein S6 modification-like protein A OS=Homo sapiens GN=RIMKLA PE=2 SV=2
HGM_OVER 155-287 -4.910 PB015954 Q6WBB3_BIFBR/1-225 PB015954; Pfam-B_15954;
JCSG1214 3-287 -73.200 15  PU9803J YP_001095162.1 381332 Crystal|NMR-2007-12-14
NEW_HUMAN_DOMAINS 188-259 -5.540 12  sp|Q96NE9|FRMD6_HUMAN FERM domain-containing protein 6 OS=Homo sapiens GN=FRMD6 PE=1 SV=1 (Range: 547-622)
PDB1214 8-287 -78.300 22  4iwx_A mol:protein length:320 Ribosomal protein S6 modification protein
PfamA27U 6-287 -39.300 PF05770.6; Q9AYJ2_ORYSJ/16-320; Inositol 1, 3, 4-trisphosphate 5/6-kinase
90-287 -69.000 23  PF08443.6; RIMK_HAEIN/105-293; RimK-like ATP-grasp domain
SCOP175 13-92 -18.500 15  d1uc8a1 c.30.1.6 (A:1-88) Lysine biosynthesis enzyme LysX, N-terminal domain {Thermus thermophilus [TaxId: 274]}
93-287 -64.000 22  d1uc8a2 d.142.1.7 (A:89-280) Lysine biosynthesis enzyme LysX ATP-binding domain {Thermus thermophilus [TaxId: 274]}
VFDB 153-275 -5.900 13  VFG0007 (gi:33592928) fimB - chaperone protein [Bordetella pertussis Tohama I] (VF0031)
13 gi|108885077|ref|NP_072673.2| methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (MG_013) [Mycoplasma genitalium G37] 273 COG1214 2-266 -113.000 28  [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
H.sapiens 2-271 -113.000 28  sp|P11586|C1TC_HUMAN C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3 (Range: 1-300)
HGM_OVER 2-202 -3.630 PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;
JCSG1214 1-267 -106.000 28  TM1767 TM1767 283621 Purified-2001-12-11
NEW_HUMAN_DOMAINS 225-272 -16.400 12  sp|Q6UB35|C1TM_HUMAN Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens GN=MTHFD1L PE=1 SV=1 (Range: 298-355)
PDB1214 2-267 -121.000 30  3p2o_A mol:protein length:285 Bifunctional protein folD
PfamA27U 2-111 -56.600 32  PF00763.18; FOLD_SHIFL/4-121; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
114-265 -80.200 23  PF02882.14; Q9ZVI8_ARATH/182-349; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
SCOP175 2-112 -57.500 33  d1b0aa2 c.58.1.2 (A:2-122) Tetrahydrofolate dehydrogenase/cyclohydrolase {Escherichia coli [TaxId: 562]}
113-267 -81.400 24  d1a4ia1 c.2.1.7 (A:127-296) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-228 -5.620 VFG1537 (gi:23954221) orf2 - hypothetical protein [Escherichia coli 536]
14 gi|12044864|ref|NP_072674.1|(removed signalp:1-25) ABC transporter, ATP-binding/permease protein (MG_014) [Mycoplasma genitalium G37] 598 COG1214 2-590 -89.700 23  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
H.sapiens 77-377 -43.700 17  sp|Q03518|TAP1_HUMAN Antigen peptide transporter 1 OS=Homo sapiens GN=TAP1 PE=1 SV=2 (Range: 301-600)
153-469 -57.600 23  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1 (Range: 301-600)
194-510 -69.500 25  sp|Q03519|TAP2_HUMAN(removed signalp:1-28) Antigen peptide transporter 2 OS=Homo sapiens GN=TAP2 PE=1 SV=1 (Range: 301-600)
312-596 -75.900 33  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1 (Range: 451-743)
HGM_OVER 377-595 -5.050 10  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
JCSG1214 1-596 -148.000 30  TM0287 TM0287 282163 Purified-2001-02-27
NEW_HUMAN_DOMAINS 343-560 -3.900 11  sp|Q9P212|PLCE1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 OS=Homo sapiens GN=PLCE1 PE=1 SV=3 (Range: 185-483)
PDB1214 1-596 -149.000 30  4q4j_A mol:protein length:587 ABC transporter
PfamA27U 1-261 -14.800 11  PF13748.1; B6R989_9RHOB/9-243; ABC transporter transmembrane region
358-517 -28.200 22  PF00005.22; YTFR_ECOLI/25-174; ABC transporter
SCOP175 2-324 -39.500 16  d2hyda2 f.37.1.1 (A:1-323) Putative multidrug export ATP-binding/permease protein SAV1866 {Staphylococcus aureus [TaxId: 1280]}
309-597 -58.200 21  d1r0wa_ c.37.1.12 (A:) Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain {Mouse (Mus musculus) [TaxId: 10090]}
340-591 -76.300 31  d1mv5a_ c.37.1.12 (A:) Multidrug resistance ABC transporter LmrA, C-terminal domain {Lactococcus lactis [TaxId: 1358]}
VFDB 3-592 -86.100 21  VFG1269 (gi:33591935) cyaB - cyclolysin secretion ATP-binding protein [Bordetella pertussis Tohama I] (VF0028)
15 gi|12044865|ref|NP_072675.1|(removed signalp:1-25) ABC transporter, ATP-binding/permease protein (MG_015) [Mycoplasma genitalium G37] 564 COG1214 3-562 -97.100 21  [V] COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
37-564 -99.900 30  [V] COG1132 ABC-type multidrug transport system, ATPase and permease components
H.sapiens 3-207 -43.400 16  sp|Q03518|TAP1_HUMAN Antigen peptide transporter 1 OS=Homo sapiens GN=TAP1 PE=1 SV=2 (Range: 151-450)
58-362 -51.100 18  sp|Q03518|TAP1_HUMAN Antigen peptide transporter 1 OS=Homo sapiens GN=TAP1 PE=1 SV=2 (Range: 301-600)
140-444 -61.700 23  sp|Q9NP78|ABCB9_HUMAN(removed signalp:1-23) ATP-binding cassette sub-family B member 9 OS=Homo sapiens GN=ABCB9 PE=1 SV=1 (Range: 301-600)
181-485 -69.200 25  sp|Q03519|TAP2_HUMAN(removed signalp:1-28) Antigen peptide transporter 2 OS=Homo sapiens GN=TAP2 PE=1 SV=1 (Range: 301-600)
288-562 -78.200 36  sp|Q9NRK6|ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens GN=ABCB10 PE=1 SV=2 (Range: 451-738)
324-564 -83.600 40  sp|O75027|ABCB7_HUMAN(removed signalp:1-16) ATP-binding cassette sub-family B member 7, mitochondrial OS=Homo sapiens GN=ABCB7 PE=1 SV=2 (Range: 451-736)
HGM_OVER 362-562 -4.400 12  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
JCSG1214 3-564 -153.000 34  TM0288 TM0288 282164 Purified-2001-02-27
NEW_HUMAN_DOMAINS 398-562 -5.110 sp|Q9C0D5|TANC1_HUMAN Protein TANC1 OS=Homo sapiens GN=TANC1 PE=1 SV=3 (Range: 691-900)
PDB1214 3-564 -153.000 34  3qf4_B mol:protein length:598 Uncharacterized ABC transporter ATP-binding p
PfamA27U 3-251 -28.000 10  PF13748.1; B6R989_9RHOB/9-243; ABC transporter transmembrane region
343-492 -28.300 28  PF00005.22; YTFR_ECOLI/25-174; ABC transporter
351-546 -9.860 11  PF13401.1; B2UJB3_RALPJ/42-210; AAA domain
SCOP175 3-311 -62.300 15  d2hyda2 f.37.1.1 (A:1-323) Putative multidrug export ATP-binding/permease protein SAV1866 {Staphylococcus aureus [TaxId: 1280]}
327-564 -85.900 36  d1mv5a_ c.37.1.12 (A:) Multidrug resistance ABC transporter LmrA, C-terminal domain {Lactococcus lactis [TaxId: 1358]}
VFDB 3-564 -98.100 24  VFG0907 (gi:26249408) hlyB - Hemolysin B [Escherichia coli CFT073] (VF0225)
16 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] (Range: 1-500) 500 COG1214 1-118 -7.820 17  [S] COG4715 Uncharacterized conserved protein
H.sapiens 1-116 -12.400 17  sp|Q9HCJ5|ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 OS=Homo sapiens GN=ZSWIM6 PE=2 SV=2 (Range: 151-450)
HGM_OVER 82-272 -4.170 14  PB038401 Q8RFH0_FUSNN/1-210 PB038401; Pfam-B_38401;
JCSG1214 65-483 -5.190 13  KN.A21292A.MR NM_000901 429771 Purified-2013-05-30
NEW_HUMAN_DOMAINS 12-116 -13.900 18  sp|Q9HCJ5|ZSWM6_HUMAN Zinc finger SWIM domain-containing protein 6 OS=Homo sapiens GN=ZSWIM6 PE=2 SV=2 (Range: 201-338)
PDB1214 51-125 -7.830 16  4b2r_A mol:protein length:126 COMPLEMENT FACTOR H
PfamA27U 46-85 -22.200 42  PF04434.12; Y020_MYCPN/46-86; SWIM zinc finger
SCOP175 65-149 -7.500 20  d1rfxa_ g.77.1.1 (A:) Resistin (ADSF, FIZZ3) {Mouse (Mus musculus) [TaxId: 10090]}
VFDB 35-120 -3.960 10  VFG0136 (gi:15595962) mucC - negative regulator for alginate biosynthesis MucB [Pseudomonas aeruginosa PAO1] (VF0091)
17 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] (Range: 251-750) 500 COG1214 32-500 -61.600 21  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
H.sapiens 102-400 -48.900 15  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2 (Range: 1051-1350)
191-469 -55.500 18  sp|Q5T890|RAD26_HUMAN Putative DNA repair and recombination protein RAD26-like OS=Homo sapiens GN=RAD26L PE=2 SV=1 (Range: 1-300)
237-500 -70.100 25  sp|Q2NKX8|ERC6L_HUMAN DNA excision repair protein ERCC-6-like OS=Homo sapiens GN=ERCC6L PE=1 SV=1 (Range: 1-300)
274-500 -73.000 30  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2 (Range: 1201-1500)
HGM_OVER 297-500 -3.560 11  HGC00166 gi|163579340|dbj|BABE01005762.1|1.0 TMP00473;
JCSG1214 108-500 -38.900 10  FR15026A NP_905257.1 392915 Crystal|NMR-2009-05-13
291-500 -46.100 29  RF3866A.HELLS BC100394 421236 Purified-2011-02-13
NEW_HUMAN_DOMAINS 366-490 -5.090 16  tr|Q5VUY5|Q5VUY5_HUMAN Chromosome 1 open reading frame 158 OS=Homo sapiens GN=C1orf158 PE=2 SV=1 (Range: 1-108)
PDB1214 159-499 -11.600 10  4a2w_A mol:protein length:936 RETINOIC ACID INDUCIBLE PROTEIN I
191-500 -23.600 15  3dmq_A mol:protein length:968 RNA polymerase-associated protein rapA
300-500 -53.500 37  1z63_A mol:protein length:500 Helicase of the snf2/rad54 family
PfamA27U 2-321 -34.900 15  PF08455.5; A4J9J5_DESRM/246-626; Bacterial SNF2 helicase associated
307-500 -49.100 23  PF00176.18; RAD54_YEAST/274-621; SNF2 family N-terminal domain
SCOP175 211-500 -20.000 12  d1rifa_ c.37.1.23 (A:) DNA helicase UvsW {Bacteriophage T4 [TaxId: 10665]}
316-500 -69.600 41  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 159-500 -52.900 23  VFG1093 (gi:15641763) VC1760 - helicase, putative [Vibrio cholerae N16961]
18 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] (Range: 501-1000) 500 COG1214 1-500 -95.300 33  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
H.sapiens 23-283 -80.000 29  sp|O14981|BTAF1_HUMAN TATA-binding protein-associated factor 172 OS=Homo sapiens GN=BTAF1 PE=1 SV=2 (Range: 1201-1500)
196-491 -91.400 24  sp|Q5FWF4|ZRAB3_HUMAN Zinc finger Ran-binding domain-containing protein 3 OS=Homo sapiens GN=ZRANB3 PE=2 SV=2 (Range: 151-450)
HGM_OVER 341-494 -4.340 14  PB007843 JCVI_PEP_1096682172521 /source_dna_id=JCVI_ORF_1096682172520 /offset=0 /translation_table=11 /length=152 /full_length=152
JCSG1214 76-500 -87.300 30  RF3866A.HELLS BC100394 421236 Purified-2011-02-13
NEW_HUMAN_DOMAINS 202-281 -6.640 15  tr|C9J818|C9J818_HUMAN Uncharacterized protein OS=Homo sapiens GN=C21orf59 PE=4 SV=1 (Range: 101-187)
PDB1214 21-500 -32.200 17  2fwr_A mol:protein length:472 DNA repair protein RAD25
50-499 -107.000 36  1z63_A mol:protein length:500 Helicase of the snf2/rad54 family
PfamA27U 57-354 -68.000 24  PF00176.18; RAD54_YEAST/274-621; SNF2 family N-terminal domain
326-500 -38.300 15  PF16203; Q0UAJ3.1/498-753; ERCC3/RAD25/XPB C-terminal helicase
SCOP175 66-296 -78.400 39  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
298-499 -61.800 36  d1z5za1 c.37.1.19 (A:663-906) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 54-500 -101.000 27  VFG1093 (gi:15641763) VC1760 - helicase, putative [Vibrio cholerae N16961]
19 gi|108885078|ref|NP_072678.2| SNF2 family helicase putative (MG_018) [Mycoplasma genitalium G37] (Range: 751-1031) 281 COG1214 1-281 -68.700 34  [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family
H.sapiens 2-281 -84.400 20  sp|Q9NZC9|SMAL1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 OS=Homo sapiens GN=SMARCAL1 PE=1 SV=1 (Range: 601-900)
HGM_OVER 91-266 -3.830 12  PB007843 JCVI_PEP_1096682172521 /source_dna_id=JCVI_ORF_1096682172520 /offset=0 /translation_table=11 /length=152 /full_length=152
JCSG1214 1-281 -55.800 27  RF3866A.HELLS BC100394 421236 Purified-2011-02-13
NEW_HUMAN_DOMAINS 171-279 -6.240 11  sp|Q9NR09|BIRC6_HUMAN Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens GN=BIRC6 PE=1 SV=2 (Range: 2039-2203)
PDB1214 27-281 -83.900 34  1z5z_A mol:protein length:271 Helicase of the snf2/rad54 family
PfamA27U 1-104 -18.200 27  PF00176.18; RAD54_YEAST/274-621; SNF2 family N-terminal domain
47-281 -32.400 10  PF11496.3; Q6FSK5_CANGA/26-299; Class II histone deacetylase complex subunits 2 and 3
77-281 -46.600 15  PF16203; Q0UAJ3.1/498-753; ERCC3/RAD25/XPB C-terminal helicase
SCOP175 1-46 -9.840 37  d1z63a1 c.37.1.19 (A:432-661) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
48-281 -80.500 35  d1z5za1 c.37.1.19 (A:663-906) Helicase of the SNF2/Rad54 hamily {Sulfolobus solfataricus [TaxId: 2287]}
VFDB 1-281 -69.700 21  VFG1093 (gi:15641763) VC1760 - helicase, putative [Vibrio cholerae N16961]
20 gi|12044869|ref|NP_072679.1| chaperone protein DnaJ (MG_019) [Mycoplasma genitalium G37] 389 COG1214 3-388 -120.000 32  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
H.sapiens 3-389 -112.000 26  sp|Q96EY1|DNJA3_HUMAN(removed signalp:1-21) DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens GN=DNAJA3 PE=1 SV=2
HGM_OVER 16-78 -3.550 17  PB009671 Q5LCM2_BACFN/1-111 PB009671; Pfam-B_9671;
JCSG1214 1-378 -122.000 31  TM0849 TM0849 282719 Selected-2001-10-12
NEW_HUMAN_DOMAINS 157-240 -8.680 13  sp|Q9H9B1|EHMT1_HUMAN Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens GN=EHMT1 PE=1 SV=4 (Range: 514-644)
PDB1214 1-375 -80.700 22  3lz8_A mol:protein length:329 Putative chaperone DnaJ
PfamA27U 7-74 -39.300 52  PF00226.26; Q22028_CAEEL/17-79; DnaJ domain
164-229 -33.300 32  PF00684.14; DNAJ1_CORGL/147-211; DnaJ central domain
285-365 -17.700 18  PF01556.13; A2FIH5_TRIVA/258-337; DnaJ C terminal domain
SCOP175 1-112 -37.600 20  d1gh6a_ a.2.3.1 (A:) Large T antigen, the N-terminal J domain {Simian virus 40, Sv40 [TaxId: 10633]}
4-83 -46.900 53  d1xbla_ a.2.3.1 (A:) DnaJ chaperone, N-terminal (J) domain {Escherichia coli [TaxId: 562]}
151-234 -36.600 31  d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}
203-277 -11.500 13  d1nlta1 b.4.1.1 (A:110-138,A:213-257) Mitochondrial protein import protein mas5 (Hsp40, Ydj1), C-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
279-367 -26.400 15  d1c3ga2 b.4.1.1 (A:260-349) Heat shock protein 40 Sis1 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 190-382 -4.550 VFG1801 (gi:153012) etb - exfoliative toxin B [Staphylococcus aureus] (VF0009)


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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Doctor KS, Reed JC, Godzik A., Bourne PE. The apoptosis database. Cell Death Differ. 2003 Jun;10(6):621-33. Review.