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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|16082692|ref|NP_395138.1| putative transposase (YPCD1.01) [Yersinia pestis CO92] 340 COG0516 1-340 -114.000 41  [L] COG4584 Transposase and inactivated derivatives
H.sapiens 1-238 -16.000 11  sp|P63135|POK12_HUMAN HERV-K_1q22 provirus ancestral Pol protein OS=Homo sapiens PE=3 SV=1 (Range: 451-750)
81-296 -22.100 11  sp|Q9QC07|POK7_HUMAN HERV-K_1q23.3 provirus ancestral Pol protein OS=Homo sapiens PE=3 SV=2 (Range: 601-812)
HGM_OVER 206-281 -3.670 13  PB047024 _Gut.Meta.Jp.0098985_ gi|162869273|dbj|BABB01000734.1||6 (+ 5047:5650~0 complete)
JCSG0516 13-127 -15.300 20  SP18059A ZP_02431199.1 410310 Selected-2009-11-12
14-326 -11.500 GD14004A RER070207002105 388710 Selected-2007-09-21
NEW_HUMAN_DOMAINS 4-85 -7.100 15  sp|Q9BWC9|CC106_HUMAN Coiled-coil domain-containing protein 106 OS=Homo sapiens GN=CCDC106 PE=1 SV=1 (Range: 181-280)
PDB0516 3-339 -18.400 12  4fcy_A mol:protein length:529 Transposase
68-296 -20.600 15  3jca_A mol:protein length:265 Integrase
118-244 -22.700 16  1asu_A mol:protein length:162 AVIAN SARCOMA VIRUS INTEGRASE
120-292 -21.200 18  5cz1_A mol:protein length:169 integrase
120-332 -18.800 13  1c0m_A mol:protein length:238 PROTEIN (INTEGRASE)
PfamA30U 2-42 -12.500 26  PF11427.6; B4MU89_DROWI/3-52; Tc3 transposase
2-111 -12.300 PF01710.14; P74195_SYNY3/1-119; Transposase
115-244 -16.500 PF00665.24; P71644_MYCTU/136-254; Integrase core domain
121-295 -12.600 PF02914.13; TRA_HAEIN/267-485; Bacteriophage Mu transposase
SCOP206 1-42 -13.000 14  d1tc3c_ a.4.1.2 (C:) Transposase tc3a1-65 {Nematode (Caenorhabditis elegans) [TaxId: 6239]}
13-98 -10.000 14  d1nr3a_ d.236.1.1 (A:) DNA-binding protein Tfx {Methanobacterium thermoautotrophicum [TaxId: 145262]}
119-244 -22.200 17  d1cxqa_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Rous sarcoma virus RSV [TaxId: 11886]}
125-292 -15.600 15  d3l3ua_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
VFDB 3-56 -9.820 16  VFG042429(gi:639968) (afaF-III) AfaF-III [Afimbrial adhesin, AFA-III (AI012)] [Escherichia coli str. A30]
2 gi|16082693|ref|NP_395139.1| transposase/IS protein (YPCD1.02) [Yersinia pestis CO92] 259 COG0516 54-250 -29.400 19  [L] COG1484 DNA replication protein
H.sapiens 8-245 -12.900 15  sp|O43933|PEX1_HUMAN Peroxisome biogenesis factor 1 OS=Homo sapiens GN=PEX1 PE=1 SV=1 (Range: 451-750)
33-238 -14.100 12  sp|Q8TD57|DYH3_HUMAN Dynein heavy chain 3, axonemal OS=Homo sapiens GN=DNAH3 PE=2 SV=1 (Range: 1951-2250)
HGM_OVER 107-212 -5.070 17  PB053359 gi|153891307|ref|ZP_02012332.1| conserved hypothetical protein [Opitutaceae bacterium TAV2]gi|151582630|gb|EDN46158.1| conserved hypothetical protein [Opitutaceae bacterium TAV2]
JCSG0516 1-243 -9.620 15  MJ8919A YP_351948.1 403413 Purified-2009-09-04
48-243 -24.800 20  NT12373A YP_804196.1 378766 Purified-2007-10-16
NEW_HUMAN_DOMAINS 87-203 -7.630 14  sp|Q8IVG5|SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like OS=Homo sapiens GN=SAMD9L PE=1 SV=2 (Range: 687-863)
PDB0516 21-227 -15.000 15  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dna
65-254 -93.900 47  5bq5_A mol:protein length:189 Insertion sequence IS5376 putative ATP-bindin
PfamA30U 56-235 -86.000 32  PF01695.15; Y4IQ_RHISN/60-238; IstB-like ATP binding protein
SCOP206 76-204 -18.500 21  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
102-241 -11.700 18  d2i3ba1 c.37.1.11 (A:1-189) Cancer-related NTPase, C1orf57 {Human (Homo sapiens) [TaxId: 9606]}
VFDB 5-237 -8.900 VFG006582(gi:15645649) (flhF) flagellar biosynthesis protein [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
3 gi|16082696|ref|NP_395142.1| secretion chaperone (YPCD1.05c) [Yersinia pestis CO92] 130 COG0516 6-123 -10.000 [S] COG5465 Uncharacterized conserved protein
H.sapiens 29-130 -6.270 sp|Q9UKN7|MYO15_HUMAN Myosin-XV OS=Homo sapiens GN=MYO15A PE=1 SV=2 (Range: 3301-3530)
HGM_OVER 1-110 -5.130 PB022506 Q11RP6_CYTH3/1-298 PB022506; Pfam-B_22506;
JCSG0516 1-130 -39.200 10  FR15113A YP_009166.1 391933 Crystal|NMR-2009-04-30
NEW_HUMAN_DOMAINS 6-64 -6.760 11  sp|Q9NZM1|MYOF_HUMAN Myoferlin OS=Homo sapiens GN=MYOF PE=1 SV=1 (Range: 1675-1754)
PDB0516 1-130 -60.800 98  1n5b_A mol:protein length:132 YOPE regulator
PfamA30U 7-118 -38.500 17  PF05932.11; Q87P37_VIBPA/6-126; Tir chaperone protein (CesT) family
SCOP206 2-118 -56.500 100  d1jyaa_ d.198.1.1 (A:) YopE chaperone SycE {Yersinia pestis [TaxId: 632]}
VFDB 1-130 -62.600 100  VFG000372(gi:16082696) (sycE/yerA) chaperone for YopE [TTSS (VF0140)] [Yersinia pestis CO92]
4 gi|16082697|ref|NP_395143.1| putative outer membrane virulence protein (YPCD1.06) [Yersinia pestis CO92] 219 COG0516 126-217 -6.640 [S] COG4718 Phage-related protein
H.sapiens 131-217 -6.470 18  sp|B1AH88|TSPOB_HUMAN Peripheral benzodiazepine receptor-related protein OS=Homo sapiens GN=TSPO PE=1 SV=1
HGM_OVER 175-219 -3.390 14  PB003564 gi|46242789|gb|AAS83494.1| TraD [Bacteroides fragilis]
JCSG0516 141-217 -5.620 SC.B20974C YP_103213.1 428467 Selected-2013-01-04
NEW_HUMAN_DOMAINS 127-217 -5.590 18  sp|Q71F23|CENPU_HUMAN Centromere protein U OS=Homo sapiens GN=MLF1IP PE=1 SV=1 (Range: 321-418)
PDB0516 18-85 -18.200 100  1l2w_I mol:protein length:69 Outer membrane virulence protein yopE
90-219 -68.100 100  1hy5_A mol:protein length:136 YERSINIA PESTIS VIRULENCE PROTEIN YOPE
PfamA30U 1-126 -34.500 100  PF09020.8; YOPE_YERPE/1-126; YopE, N terminal
127-195 -41.000 39  PF03545.11; Q9I788_PSEAE/132-201; Yersinia virulence determinant (YopE)
SCOP206 22-78 -13.900 100  d1l2wi_ d.198.1.1 (I:) YopE chaperone SycE {Yersinia pestis [TaxId: 632]}
100-219 -64.200 100  d1hy5a_ a.24.11.1 (A:) YopE {Yersinia pestis [TaxId: 632]}
VFDB 1-219 -105.000 100  VFG000373(gi:16082697) (yopE) type III secretion system effector YopE, GTPase activating protein (GAP) [TTSS (VF0140)] [Yersinia pestis CO92]
5 gi|16082698|ref|NP_395144.1| hypothetical protein (YPCD1.07) [Yersinia pestis CO92] 98 COG0516 39-98 -7.090 20  [S] COG4713 Predicted membrane protein
H.sapiens 27-81 -13.300 20  sp|Q9H5I5|PIEZ2_HUMAN(removed signalp:1-24) Protein PIEZO2 OS=Homo sapiens GN=FAM38B PE=2 SV=2 (Range: 1651-1950)
HGM_OVER 5-56 -4.310 25  HGC00552 gi|162599220|dbj|BAAV01006262.1|2.0 TMP00636;
JCSG0516 42-73 -7.180 25  SP18382A NP_371220.1 413717 Purified-2010-09-29
NEW_HUMAN_DOMAINS 24-61 -5.870 13  sp|P86479|PR20C_HUMAN Proline-rich protein 20C OS=Homo sapiens GN=PRR20C PE=4 SV=1 (Range: 134-221)
PDB0516 30-76 -6.300 2m51_A mol:protein length:62 Ras GTPase-activating protein 1
PfamA30U 5-97 -7.770 13  PF09323.8; Q5M538_STRT2/1-178; Domain of unknown function (DUF1980 topsan)
SCOP206 7-88 -6.730 11  d1vg0a2 d.16.1.6 (A:445-557) Rab escort protein 1 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 1-98 -6.600 14  VFG002151(gi:15605597) (copB2) Type III secretion system translocator CopB2 [TTSS (VF0344)] [Chlamydia trachomatis D/UW-3/CX]
6 gi|16082699|ref|NP_395145.1| hypothetical protein (YPCD1.08c) [Yersinia pestis CO92] 99 COG0516 2-94 -62.100 31  [R] COG3668 Plasmid stabilization system protein
H.sapiens 3-99 -5.870 sp|O60477|DBC1_HUMAN(removed signalp:1-19) Deleted in bladder cancer protein 1 OS=Homo sapiens GN=DBC1 PE=2 SV=2 (Range: 451-742)
HGM_OVER 2-83 -3.700 11  PB128892 A6TNK2_9CLOT/1-174 PB128892; Pfam-B_128892;
JCSG0516 4-94 -6.160 11  RH10496C ZP_02078944.1 416275 Selected-2009-12-04
NEW_HUMAN_DOMAINS 60-88 -5.450 20  sp|A3KMH1|K0564_HUMAN Uncharacterized protein KIAA0564 OS=Homo sapiens GN=KIAA0564 PE=1 SV=2 (Range: 1230-1332)
PDB0516 2-94 -62.300 30  3kxe_A mol:protein length:110 Toxin protein parE-1
PfamA30U 5-89 -22.900 21  PF05016.13; A0A023JAP0_SALTM/4-92; ParE toxin of type II toxin-antitoxin system, parDE
SCOP206 3-87 -7.900 12  d1wmia1 d.298.1.2 (A:1-88) Hypothetical protein PHS013 {Pyrococcus horikoshii [TaxId: 53953]}
VFDB 30-83 -5.200 18  VFG002071(gi:15595283) (hcp1) type VI secretion system substrate Hcp1 [HSI-I (VF0334)] [Pseudomonas aeruginosa PAO1]
7 gi|40548796|ref|NP_395146.2| hypothetical protein (YPCD1.09c) [Yersinia pestis CO92] 80 COG0516 1-78 -38.800 34  [K] COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain
H.sapiens 5-60 -6.810 25  sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=1 SV=2 (Range: 151-450)
HGM_OVER 3-76 -4.130 23  HGC00962 gi|162759780|dbj|BAAZ01005693.1|3.0 TMP01305;
JCSG0516 3-77 -36.200 30  PD03693I MMAG_12JAN01_CONTIG3876_REVISED_GENE3789 366510 Purified-2006-04-03
NEW_HUMAN_DOMAINS 11-56 -5.540 28  sp|Q02818|NUCB1_HUMAN Nucleobindin-1 OS=Homo sapiens GN=NUCB1 PE=1 SV=4 (Range: 49-194)
PDB0516 1-80 -46.200 30  3kxe_C mol:protein length:88 Antitoxin protein parD-1
PfamA30U 1-80 -48.200 33  PF03693.12; PARD1_MYCTU/1-80; Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
SCOP206 3-45 -13.900 32  d2hzaa1 a.43.1.3 (A:1-48) Nickel responsive regulator NikR, N-terminal domain {Escherichia coli [TaxId: 562]}
VFDB 6-60 -5.060 14  VFG002508(gi:53717911) (flgB) flagellar basal-body rod protein FlgB [Flagella (VF0430)] [Burkholderia pseudomallei K96243]
8 gi|16082702|ref|NP_395148.1| plasmid-partitioning protein (YPCD1.12c) [Yersinia pestis CO92] 320 COG0516 2-156 -20.700 [L] KOG3388 Predicted transcription regulator/nuclease, contains ParB domain
61-320 -35.900 11  [K] COG1475 Predicted transcriptional regulators
H.sapiens 61-158 -21.600 sp|Q9BYN0|SRXN1_HUMAN Sulfiredoxin-1 OS=Homo sapiens GN=SRXN1 PE=1 SV=2
HGM_OVER 140-211 -5.190 13  HGC00573 gi|163306732|dbj|BABD01003960.1|2.0 TMP00669;
JCSG0516 107-213 -11.400 15  RH14964A NP_842531.1 416114 Selected-2009-12-04
NEW_HUMAN_DOMAINS 70-215 -3.940 12  tr|Q5T5A0|Q5T5A0_HUMAN Chromosome 9 open reading frame 24 OS=Homo sapiens GN=C9orf24 PE=2 SV=1 (Range: 1-164)
PDB0516 1-278 -41.200 19  4umk_A mol:protein length:240 PROBABLE CHROMOSOME-PARTITIONING PROTEIN PARB
72-257 -43.200 21  1vz0_A mol:protein length:230 CHROMOSOME PARTITIONING PROTEIN PARB
145-317 -51.300 41  3mky_B mol:protein length:189 Protein sopB
PfamA30U 72-156 -22.900 27  PF02195.16; PARB_CHLTR/12-105; ParB-like nuclease domain
157-317 -22.200 PF07506.9; Q9F5B9_AGRRH/157-326; RepB plasmid partitioning protein
SCOP206 72-159 -28.200 26  d1vz0a2 d.268.1.1 (A:23-115) Putative partitioning protein ParB/Spo0J {Thermus thermophilus [TaxId: 274]}
159-257 -18.700 16  d1vz0a1 a.4.14.1 (A:116-208) Putative partitioning protein ParB/Spo0J {Thermus thermophilus [TaxId: 274]}
VFDB 49-198 -6.090 VFG000458(gi:16764500) (csgA) curlin major subunit CsgA [Agf (VF0103)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
9 gi|16082703|ref|NP_395149.1| plasmid-partitioning protein SopA (YPCD1.13c) [Yersinia pestis CO92] 388 COG0516 66-387 -23.700 16  [D] COG0455 ATPases involved in chromosome partitioning
105-374 -60.600 19  [D] COG1192 ATPases involved in chromosome partitioning
H.sapiens 108-376 -17.300 12  sp|Q9Y5Y2|NUBP2_HUMAN Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens GN=NUBP2 PE=1 SV=1
HGM_OVER 232-341 -6.050 PB019388 gi|83589066|ref|YP_429075.1| Radical SAM [Moorella thermoacetica ATCC 39073]gi|83571980|gb|ABC18532.1| Radical SAM [Moorella thermoacetica ATCC 39073]
JCSG0516 2-387 -98.000 26  MJ12015E NP_436589.1 403711 Purified-2009-09-18
NEW_HUMAN_DOMAINS 107-151 -6.130 17  sp|Q96MS3|GL1D1_HUMAN Glycosyltransferase 1 domain-containing protein 1 OS=Homo sapiens GN=GLT1D1 PE=2 SV=2 (Range: 1-57)
PDB0516 1-387 -78.800 21  3ez2_A mol:protein length:398 Plasmid partition protein A
PfamA30U 106-291 -62.900 26  PF13614.4; R7M636_9CLOT/2-188; AAA domain
107-380 -35.500 13  PF07015.9; Q1M9M0_RHIL3/1-231; VirC1 protein
109-348 -57.600 22  PF01656.21; P72976_SYNY3/5-270; CobQ/CobB/MinD/ParA nucleotide binding domain
SCOP206 105-374 -66.600 25  d1wcv1_ c.37.1.0 (1:) automated matches {Thermus thermophilus [TaxId: 262724]}
VFDB 83-379 -24.800 14  VFG043385(gi:15645648) (ylxH) ATP-binding protein [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
10 gi|40548797|ref|NP_954989.1| hypothetical protein (YPCD1.14n) [Yersinia pestis CO92] 65 COG0516 1-65 -18.800 20  [L] COG2801 Transposase and inactivated derivatives
H.sapiens 1-49 -6.080 10  sp|Q9UGI0|ZRAN1_HUMAN Ubiquitin thioesterase ZRANB1 OS=Homo sapiens GN=ZRANB1 PE=1 SV=2 (Range: 301-600)
HGM_OVER 21-58 -3.840 HGC00965 gi|163282470|dbj|BABD01028218.1|2.0 TMP01310;
JCSG0516 2-64 -14.300 17  GD14004A RER070207002105 388710 Selected-2007-09-21
NEW_HUMAN_DOMAINS 4-29 -7.990 15  tr|D6RIX7|D6RIX7_HUMAN Uncharacterized protein OS=Homo sapiens GN=USP46 PE=4 SV=1 (Range: 1-56)
PDB0516 2-49 -6.280 15  3phu_A mol:protein length:219 RNA-directed RNA polymerase L
PfamA30U 18-65 -23.100 25  PF13333.4; Q5F880_NEIG1/215-270; Integrase core domain
SCOP206 1-45 -7.170 20  d1tocr1 g.8.1.2 (R:1A-56) Ornithodorin {Soft tick (Ornithodoros moubata) [TaxId: 6938]}
VFDB 1-62 -4.360 12  VFG041337(gi:52842664) (ankD/legA15) Dot/Icm type IV secretion system effector AnkD/LegA15 [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
11 gi|16082705|ref|NP_395151.1| hypothetical protein (YPCD1.15c) [Yersinia pestis CO92] 152 COG0516 1-152 -33.100 17  [L] COG2801 Transposase and inactivated derivatives
H.sapiens 103-149 -9.870 19  sp|P10266|POK10_HUMAN HERV-K_5q33.3 provirus ancestral Pol protein OS=Homo sapiens PE=3 SV=2 (Range: 451-750)
HGM_OVER 4-138 -4.350 14  PB007843 JCVI_PEP_1096682172521 /source_dna_id=JCVI_ORF_1096682172520 /offset=0 /translation_table=11 /length=152 /full_length=152
JCSG0516 1-152 -25.900 GD14004A RER070207002105 388710 Selected-2007-09-21
NEW_HUMAN_DOMAINS 23-152 -7.050 16  sp|Q8IZY2|ABCA7_HUMAN ATP-binding cassette sub-family A member 7 OS=Homo sapiens GN=ABCA7 PE=1 SV=3 (Range: 239-549)
PDB0516 1-152 -17.500 13  4fcy_A mol:protein length:529 Transposase
PfamA30U 23-78 -17.800 21  PF13276.4; Q1WUI0_LACS1/209-271; HTH-like domain
99-152 -11.500 11  PF02914.13; TRA_HAEIN/267-485; Bacteriophage Mu transposase
SCOP206 103-152 -12.900 14  d1bcoa2 c.55.3.3 (A:258-480) mu transposase, core domain {Bacteriophage Mu [TaxId: 10677]}
VFDB 5-152 -6.630 17  VFG000973(gi:15675811) (speB) pyrogenic exotoxin B [SpeB (VF0249)] [Streptococcus pyogenes M1 GAS]
12 gi|16082706|ref|NP_395152.1| hypothetical protein (YPCD1.16c) [Yersinia pestis CO92] 107 COG0516 7-107 -49.700 28  [L] COG2963 Transposase and inactivated derivatives
H.sapiens 4-101 -12.300 12  sp|Q9P215|POGK_HUMAN Pogo transposable element with KRAB domain OS=Homo sapiens GN=POGK PE=1 SV=2 (Range: 151-450)
HGM_OVER 20-97 -5.190 PB000520 Q9RVX4_DEIRA/1-194 PB000520; Pfam-B_520;
JCSG0516 7-107 -24.400 11  SP17613A YP_975059.1 412345 Purified-2010-09-29
NEW_HUMAN_DOMAINS 71-93 -5.980 21  tr|B5MDG7|B5MDG7_HUMAN Uncharacterized protein OS=Homo sapiens GN=HMG20B PE=4 SV=2 (Range: 199-286)
PDB0516 9-104 -37.300 20  2jn6_A mol:protein length:97 Protein Cgl2762
PfamA30U 8-83 -42.900 44  PF01527.18; G3XCY0_PSEAE/3-78; Transposase
SCOP206 9-95 -37.500 18  d2jn6a1 a.4.1.19 (A:1-89) Uncharacterized protein Cgl2762 {Corynebacterium glutamicum [TaxId: 1718]}
VFDB 9-92 -6.810 11  VFG015512(gi:15599408) (phzD1) phenazine biosynthesis protein PhzD, isochorismatase [Phenazines biosynthesis (CVF536)] [Pseudomonas aeruginosa PAO1]
13 gi|16082708|ref|NP_395154.1| Yop targeting protein (YPCD1.19c) [Yersinia pestis CO92] 182 COG0516 38-156 -5.990 12  [S] COG3205 Predicted membrane protein
H.sapiens 22-182 -9.330 27  sp|Q96T58|MINT_HUMAN Msx2-interacting protein OS=Homo sapiens GN=SPEN PE=1 SV=1 (Range: 1351-1650)
HGM_OVER 11-63 -4.240 17  PB092941 Q45777_BACTN/1-139 PB092941; Pfam-B_92941;
JCSG0516 45-130 -8.740 19  SC.B20974D YP_110283.1 428517 Selected-2013-01-04
NEW_HUMAN_DOMAINS 28-111 -8.430 13  tr|B5MCI2|B5MCI2_HUMAN Uncharacterized protein OS=Homo sapiens PE=4 SV=1 (Range: 1-116)
PDB0516 15-181 -7.670 13  4ubq_A mol:protein length:229 Beta-lactamase
PfamA30U 25-171 -6.860 17  PF02476.13; Q285F6_9ALPH/8-166; US2 family
SCOP206 51-169 -7.820 15  d1ee8a2 b.113.1.1 (A:1-121) DNA repair protein MutM (Fpg) {Thermus thermophilus [TaxId: 274]}
VFDB 1-182 -146.000 100  VFG000374(gi:16082708) (yopK/yopQ) type III secretion system effector YopK/YopQ, regulating Yops injection from within host cells [TTSS (VF0140)] [Yersinia pestis CO92]
14 gi|16082709|ref|NP_395155.1| Yop targeted effector (YPCD1.20) [Yersinia pestis CO92] 322 COG0516 139-290 -9.920 14  [R] COG3271 Predicted double-glycine peptidase
H.sapiens 258-321 -7.700 18  sp|Q8IY82|CC135_HUMAN Coiled-coil domain-containing protein 135 OS=Homo sapiens GN=CCDC135 PE=2 SV=3 (Range: 301-600)
HGM_OVER 236-322 -4.170 PB048420 Q64S71_BACFR/1-165 PB048420; Pfam-B_48420;
JCSG0516 1-290 -12.600 12  SP18431A ZP_02993239.1 410515 Purified-2010-11-20
NEW_HUMAN_DOMAINS 258-321 -8.740 18  sp|Q8IY82|CC135_HUMAN Coiled-coil domain-containing protein 135 OS=Homo sapiens GN=CCDC135 PE=2 SV=3 (Range: 295-377)
PDB0516 122-315 -48.400 13  1ukf_A mol:protein length:188 Avirulence protein AVRPPH3
PfamA30U 103-320 -81.200 100  PF03543.12; YOPT_YERPE/103-320; Yersinia/Haemophilus virulence surface antigen
SCOP206 122-315 -48.900 14  d1ukfa1 d.3.1.10 (A:81-267) Avirulence protein Avrpph3 {Pseudomonas syringae pv. phaseolicola [TaxId: 319]}
VFDB 1-322 -126.000 100  VFG000375(gi:16082709) (yopT) type III secretion system effector YopT, cysteine protease [TTSS (VF0140)] [Yersinia pestis CO92]
15 gi|16082710|ref|NP_395156.1| YopT chaperone (YPCD1.21) [Yersinia pestis CO92] 132 COG0516 3-127 -5.490 11  [V] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes
H.sapiens 1-106 -7.020 13  sp|Q9Y4G8|RPGF2_HUMAN Rap guanine nucleotide exchange factor 2 OS=Homo sapiens GN=RAPGEF2 PE=1 SV=1 (Range: 451-750)
HGM_OVER 2-131 -2.440 10  PB034180 _Gut.Meta.Jp.0112129_ gi|163310377|dbj|BABD01000320.1||2 (+ 509:1679~0 complete)
JCSG0516 1-132 -29.500 10  FR15113A YP_009166.1 391933 Crystal|NMR-2009-04-30
NEW_HUMAN_DOMAINS 3-74 -6.430 11  sp|Q5XUX0|FBX31_HUMAN F-box only protein 31 OS=Homo sapiens GN=FBXO31 PE=1 SV=2 (Range: 121-219)
PDB0516 1-132 -60.000 98  2bho_A mol:protein length:130 CHAPERONE PROTEIN SYCT
PfamA30U 8-114 -29.600 15  PF05932.11; Q87P37_VIBPA/6-126; Tir chaperone protein (CesT) family
SCOP206 1-118 -43.000 17  d1s28a1 d.198.1.1 (A:3-130) AvrPphF ORF1, chaperone of AvrPphF ORF2 {Pseudomonas syringae pv. phaseolicola [TaxId: 319]}
VFDB 1-132 -70.700 100  VFG000376(gi:16082710) (sycT) chaperone for YopT [TTSS (VF0140)] [Yersinia pestis CO92]
16 gi|16082711|ref|NP_395157.1| hypothetical protein (YPCD1.22c) [Yersinia pestis CO92] 129 COG0516 4-127 -6.860 17  [S] COG1584 Predicted membrane protein
H.sapiens 28-129 -7.170 sp|Q5JTV8|TOIP1_HUMAN Torsin-1A-interacting protein 1 OS=Homo sapiens GN=TOR1AIP1 PE=1 SV=2
HGM_OVER 1-129 -4.390 PB012823 Q5LCS8_BACFN/1-272 PB012823; Pfam-B_12823;
JCSG0516 5-119 -7.730 12  TM1800 TM1800 283653 Purified-2001-12-11
NEW_HUMAN_DOMAINS 94-125 -7.140 25  sp|Q9ULL1|PKHG1_HUMAN Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens GN=PLEKHG1 PE=1 SV=2 (Range: 834-944)
PDB0516 23-124 -6.310 3jb9_h mol:protein length:265 Pre-mRNA-splicing factor cwf15
PfamA30U 4-127 -7.470 16  PF01184.17; A7TND9_VANPO/71-277; GPR1/FUN34/yaaH family
SCOP206 89-124 -5.690 16  d2pywa_ d.144.1.0 (A:) automated matches {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}
VFDB 103-128 -5.360 19  VFG007189(gi:28901197) (vscR2) type III secretion system C-ring protein VscR2 [T3SS2 (VF0409)] [Vibrio parahaemolyticus RIMD 2210633]
17 gi|16082712|ref|NP_395158.1| hypothetical protein (YPCD1.23) [Yersinia pestis CO92] 139 COG0516 5-90 -8.050 12  [TR] KOG4019 Calcineurin-mediated signaling pathway inhibitor DSCR1
H.sapiens 2-91 -8.110 15  sp|Q96T37|RBM15_HUMAN Putative RNA-binding protein 15 OS=Homo sapiens GN=RBM15 PE=1 SV=2 (Range: 1-300)
HGM_OVER 1-48 -4.110 20  HGC00993 gi|163626727|dbj|BABG01009540.1|1.0 TMP01352;
JCSG0516 11-101 -8.520 20  SP5917A YP_001712366.1 406310 Purified-2010-09-29
NEW_HUMAN_DOMAINS 1-109 -6.030 11  sp|Q5VU65|P210L_HUMAN Nuclear pore membrane glycoprotein 210-like OS=Homo sapiens GN=NUP210L PE=2 SV=1 (Range: 526-695)
PDB0516 11-94 -10.200 16  2cpj_A mol:protein length:99 Non-POU domain-containing octamer-binding pro
PfamA30U 8-127 -7.170 21  PF01698.14; W5BCH7_WHEAT/1-380; Floricaula / Leafy protein
SCOP206 11-94 -9.340 16  d2rs8a1 d.58.7.1 (A:68-153) Non-POU domain-containing octamer-binding protein, NonO {Mouse (Mus musculus) [TaxId: 10090]}
VFDB 8-85 -5.600 15  VFG000032(gi:33591345) (bplG) probable sugar transferase [LPS (VF0033)] [Bordetella pertussis Tohama I]
18 gi|16082715|ref|NP_395161.1| secreted effector protein (YPCD1.26c) [Yersinia pestis CO92] 409 COG0516 1-409 -39.500 17  [T] KOG4194 Membrane glycoprotein LIG-1
H.sapiens 1-409 -43.700 25  sp|A6NIV6|LRIQ4_HUMAN Leucine-rich repeat and IQ domain-containing protein 4 OS=Homo sapiens GN=LRRIQ4 PE=2 SV=2
HGM_OVER 123-381 -1.290 13  PB034679 gi|150005530|ref|YP_001300274.1| hypothetical protein BVU_3014 [Bacteroides vulgatus ATCC 8482]gi|149933954|gb|ABR40652.1| conserved hypothetical protein [Bacteroides vulgatus ATCC 8482]
JCSG0516 1-397 -49.800 18  SP16667C ZP_03460298.1 407555 Crystal|NMR-2011-11-13
NEW_HUMAN_DOMAINS 144-406 -4.880 11  sp|O95477|ABCA1_HUMAN ATP-binding cassette sub-family A member 1 OS=Homo sapiens GN=ABCA1 PE=1 SV=3 (Range: 48-335)
PDB0516 1-409 -75.900 94  1g9u_A mol:protein length:454 OUTER PROTEIN YOPM
PfamA30U 136-263 -19.700 18  PF14580.4; H3BFR2_LATCH/1-175; Leucine-rich repeat
SCOP206 34-386 -69.800 100  d1jl5a_ c.10.2.6 (A:) Leucine rich effector protein YopM {Yersinia pestis [TaxId: 632]}
VFDB 1-409 -81.100 100  VFG000377(gi:16082715) (yopM) type III secretion system effector YopM [TTSS (VF0140)] [Yersinia pestis CO92]
19 gi|16082716|ref|NP_395162.1| secreted effector protein (YPCD1.28c) [Yersinia pestis CO92] 306 COG0516 12-299 -11.800 [S] COG1511 Predicted membrane protein
70-300 -16.100 11  [S] COG4372 Uncharacterized protein conserved in bacteria with the myosin-like domain
H.sapiens 70-302 -15.700 10  sp|Q9Y250|LZTS1_HUMAN Leucine zipper putative tumor suppressor 1 OS=Homo sapiens GN=LZTS1 PE=1 SV=3
103-302 -16.100 10  sp|Q8IY18|SMC5_HUMAN Structural maintenance of chromosomes protein 5 OS=Homo sapiens GN=SMC5 PE=1 SV=2 (Range: 301-600)
HGM_OVER 168-302 -9.770 13  PB162020 _JGI.0344610_ 2004040329 [Human Gut Community Subject 8]
JCSG0516 24-303 -12.200 SP13496O NP_810425.1 408730 Selected-2009-11-12
70-297 -14.100 SP17722H YP_002938876.1 411110 Selected-2009-11-12
159-301 -17.600 SP18791A YP_001271634.1 411947 Selected-2009-11-12
NEW_HUMAN_DOMAINS 202-302 -8.680 sp|Q8IYM0|F186B_HUMAN Protein FAM186B OS=Homo sapiens GN=FAM186B PE=2 SV=2 (Range: 199-316)
PDB0516 72-302 -12.500 4e40_A mol:protein length:252 Putative uncharacterized protein
100-297 -14.000 4gkw_A mol:protein length:167 Spindle assembly abnormal protein 6
159-298 -18.400 10  3tul_A mol:protein length:158 Cell invasion protein sipB
PfamA30U 59-306 -64.400 100  PF05844.10; O68699_YERPE/13-306; YopD protein
SCOP206 165-300 -10.400 12  d2ap3a1 a.24.27.1 (A:12-196) Hypothetical protein MW0975 (SA0943) {Staphylococcus aureus [TaxId: 1280]}
VFDB 1-306 -86.700 100  VFG000378(gi:16082716) (yopD) type III secretion system hydrophobic translocator, pore protein YopD [TTSS (VF0140)] [Yersinia pestis CO92]
20 gi|16082717|ref|NP_395163.1| secreted effector protein (YPCD1.29c) [Yersinia pestis CO92] 401 COG0516 1-401 -95.200 100  [S] COG5613 Uncharacterized conserved protein
H.sapiens 116-399 -11.900 sp|Q9BWW8|APOL6_HUMAN Apolipoprotein L6 OS=Homo sapiens GN=APOL6 PE=2 SV=1
HGM_OVER 115-208 -7.040 HGC00928 gi|162868028|dbj|BABB01001979.1|3.0 TMP01255;
JCSG0516 149-353 -8.920 13  SP2600AD YP_794564.1 411897 Selected-2009-11-12
NEW_HUMAN_DOMAINS 98-186 -7.190 11  sp|Q6P996|PDXD1_HUMAN Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens GN=PDXDC1 PE=1 SV=2 (Range: 485-677)
PDB0516 47-264 -52.100 46  3wxx_B mol:protein length:219 AopB
PfamA30U 108-397 -51.600 13  PF04888.10; BIPB_BURPS/286-616; Secretion system effector C (SseC) like family
SCOP206 111-159 -6.990 16  d4ihje_ a.137.10.1 (E:) Stathmin 4 {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 1-401 -95.200 100  VFG000379(gi:16082717) (yopB) type III secretion system hydrophobic translocator, pore protein YopB [TTSS (VF0140)] [Yersinia pestis CO92]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]