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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|15922991|ref|NP_370525.1| chromosomal replication initiation protein (SAV0001) [Staphylococcus aureus subsp. aureus Mu50] 453 COG0516 1-452 -134.000 37  [L] COG0593 ATPase involved in DNA replication initiation
H.sapiens 126-449 -11.000 14  sp|Q99741|CDC6_HUMAN Cell division control protein 6 homolog OS=Homo sapiens GN=CDC6 PE=1 SV=1
152-290 -12.500 23  sp|O43933|PEX1_HUMAN Peroxisome biogenesis factor 1 OS=Homo sapiens GN=PEX1 PE=1 SV=1 (Range: 451-750)
152-359 -12.100 16  sp|O15381|NVL_HUMAN Nuclear valosin-containing protein-like OS=Homo sapiens GN=NVL PE=1 SV=1 (Range: 601-856)
152-404 -11.800 13  sp|Q6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 OS=Homo sapiens GN=ATAD2 PE=1 SV=1 (Range: 451-750)
HGM_OVER 185-338 -3.470 11  HGC00374 gi|162831834|dbj|BABA01012875.1|1.0 TMP00304;
JCSG0516 2-451 -128.000 30  C.LS21333A NP_418828.1 430427 Purified-2014-07-08
NEW_HUMAN_DOMAINS 131-268 -5.810 15  sp|Q8IVG5|SAM9L_HUMAN Sterile alpha motif domain-containing protein 9-like OS=Homo sapiens GN=SAMD9L PE=1 SV=2 (Range: 687-863)
PDB0516 6-452 -130.000 35  2z4r_A mol:protein length:440 Chromosomal replication initiator protein dna
PfamA30U 4-67 -16.700 20  PF11638.6; DNAA_LAWIP/5-67; DnaA N-terminal domain
116-334 -107.000 64  PF00308.16; DNAA_STRCO/317-535; Bacterial dnaA protein
361-429 -37.100 69  PF08299.9; D9QS97_ACEAZ/358-426; Bacterial dnaA protein helix-turn-helix
SCOP206 114-329 -99.700 37  d1l8qa2 c.37.1.20 (A:77-289) Chromosomal replication initiation factor DnaA {Aquifex aeolicus [TaxId: 63363]}
346-452 -45.700 34  d1l8qa1 a.4.12.2 (A:290-399) Chromosomal replication initiation factor DnaA C-terminal domain IV {Aquifex aeolicus [TaxId: 63363]}
VFDB 152-387 -7.190 14  VFG002380(gi:15611004) (eccA1) ESX-1 type VII secretion system AAA+ ATPase EccA1 [ESX-1 (VF0315)] [Mycobacterium tuberculosis H37Rv]
2 gi|15922992|ref|NP_370526.1| DNA polymerase III subunit beta (SAV0002) [Staphylococcus aureus subsp. aureus Mu50] 377 COG0516 2-377 -90.200 25  [L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)
H.sapiens 135-372 -9.690 16  sp|Q6WBX8|RAD9B_HUMAN Cell cycle checkpoint control protein RAD9B OS=Homo sapiens GN=RAD9B PE=1 SV=2
HGM_OVER 208-358 -2.940 15  PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;
JCSG0516 1-376 -110.000 40  XB5465A NP_344555.1 358603 PDB-2005-08-31
NEW_HUMAN_DOMAINS 89-344 -5.020 sp|Q8IX01|SUGP2_HUMAN SURP and G-patch domain-containing protein 2 OS=Homo sapiens GN=SUGP2 PE=1 SV=2 (Range: 297-540)
PDB0516 2-377 -113.000 54  4tr6_A mol:protein length:380 DNA polymerase III subunit beta
PfamA30U 2-127 -36.600 27  PF00712.17; DPO3B_CAUCR/1-121; DNA polymerase III beta subunit, N-terminal domain
137-251 -48.100 29  PF02767.14; DPO3B_PSEPK/129-244; DNA polymerase III beta subunit, central domain
253-375 -55.300 49  PF02768.13; DPO3B_BACSU/253-376; DNA polymerase III beta subunit, C-terminal domain
SCOP206 2-128 -45.100 23  d1vpka1 d.131.1.1 (A:1-120) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
131-252 -52.800 27  d4k3la2 d.131.1.1 (A:123-244) DNA polymerase III, beta subunit {Escherichia coli [TaxId: 562]}
253-376 -47.000 30  d1vpka3 d.131.1.1 (A:244-366) DNA polymerase III, beta subunit {Thermotoga maritima [TaxId: 2336]}
VFDB 19-293 -3.690 13  VFG001287(gi:21284317) (icaB) N-deacetylase, involved in polysaccharide intercellular adhesin(PIA) synthesis [Intercellular adhesion proteins (VF0014)] [Staphylococcus aureus subsp. aureus MW2]
3 gi|15922993|ref|NP_370527.1| hypothetical protein (SAV0003) [Staphylococcus aureus subsp. aureus Mu50] 81 COG0516 4-65 -42.200 43  [S] COG2501 Uncharacterized conserved protein
H.sapiens 12-63 -9.860 13  sp|Q9P0P8|CF203_HUMAN Uncharacterized protein C6orf203 OS=Homo sapiens GN=C6orf203 PE=1 SV=1
HGM_OVER 4-70 -5.080 13  PB011023 A7V2G7_BACUN/1-167 PB011023; Pfam-B_11023;
JCSG0516 14-63 -13.500 28  SP0223F ZP_04009405.1 413831 Purified-2010-09-29
NEW_HUMAN_DOMAINS 19-81 -6.070 12  sp|Q5H9I0|TFDP3_HUMAN Transcription factor Dp family member 3 OS=Homo sapiens GN=TFDP3 PE=1 SV=1 (Range: 1-100)
PDB0516 7-70 -38.000 26  1p9k_A mol:protein length:79 orf, hypothetical protein
PfamA30U 8-70 -39.700 34  PF13275.4; D4IXS8_BUTFI/4-68; S4 domain
SCOP206 7-70 -38.000 26  d1o09a1 d.66.1.6 (A:3-79) Hypothetical protein YbcJ {Escherichia coli [TaxId: 562]}
VFDB 11-81 -6.680 15  VFG000363(gi:16122159) (irp2) yersiniabactin biosynthetic protein Irp2 [Yersiniabactin (VF0136)] [Yersinia pestis CO92]
4 gi|15922994|ref|NP_370528.1| recombination protein F (SAV0004) [Staphylococcus aureus subsp. aureus Mu50] 370 COG0516 1-370 -108.000 23  [L] COG1195 Recombinational DNA repair ATPase (RecF pathway)
H.sapiens 3-254 -16.800 15  sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo sapiens GN=RAD50 PE=1 SV=1 (Range: 1-300)
HGM_OVER 38-225 -2.790 PB037276 Q24TM0_DESHY/1-190 PB037276; Pfam-B_37276;
JCSG0516 1-360 -22.700 15  NT12358C DHAF_12NOV03_CONTIG1086_REVISED_GENE3509 378730 Purified-2008-01-24
NEW_HUMAN_DOMAINS 287-370 -5.740 15  sp|Q7Z7G8|VP13B_HUMAN Vacuolar protein sorting-associated protein 13B OS=Homo sapiens GN=VPS13B PE=1 SV=2 (Range: 1322-1403)
PDB0516 1-370 -119.000 28  2o5v_A mol:protein length:359 DNA replication and repair protein recF
PfamA30U 1-346 -20.700 14  PF13175.4; I1YS32_PREI7/1-378; AAA ATPase domain
SCOP206 1-360 -27.200 18  g1f2t.1 c.37.1.12 (A:,B:) Rad50 {Pyrococcus furiosus [TaxId: 2261]}
VFDB 2-340 -10.200 16  VFG037118(gi:15676638) (recN) DNA repair protein RecN [RecN (VF0457)] [Neisseria meningitidis MC58]
5 gi|15922995|ref|NP_370529.1| DNA gyrase subunit B (SAV0005) [Staphylococcus aureus subsp. aureus Mu50] 644 COG0516 7-644 -158.000 56  [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
H.sapiens 2-251 -51.500 20  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 1-300)
91-402 -66.700 15  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 151-450)
249-546 -78.300 23  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 301-600)
405-641 -53.400 29  sp|Q02880|TOP2B_HUMAN DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3 (Range: 451-750)
HGM_OVER 466-634 -4.180 17  HGC00522 gi|163636101|dbj|BABG01000172.1|3.0 TMP00580;
JCSG0516 12-644 -200.000 53  TM0833 TM0833 282703 Purified-2005-04-05
NEW_HUMAN_DOMAINS 257-398 -7.080 10  sp|Q8N6G2|CM026_HUMAN Uncharacterized protein C13orf26 OS=Homo sapiens GN=C13orf26 PE=2 SV=1 (Range: 105-289)
PDB0516 2-641 -193.000 51  4juo_C mol:protein length:670 DNA topoisomerase 4 subunit B
PfamA30U 232-401 -85.200 44  PF00204.23; A9KS52_CLOPH/226-396; DNA gyrase B
542-643 -23.500 19  PF16898.3; K5XBZ3_PHACS/641-767; C-terminal associated domain of TOPRIM
575-634 -45.000 65  PF00986.19; M9X0E0_MANHA/738-800; DNA gyrase B subunit, carboxyl terminus
SCOP206 24-231 -91.600 65  d4k4oa1 d.122.1.0 (A:18-224) automated matches {Enterococcus faecalis [TaxId: 226185]}
232-403 -86.400 40  d1kija1 d.14.1.3 (A:221-392) DNA gyrase B {Thermus thermophilus [TaxId: 274]}
424-624 -97.500 60  d3m4ia_ e.78.1.1 (A:) DNA gyrase beta-prime domain {Mycobacterium tuberculosis [TaxId: 1773]}
VFDB 2-540 -6.520 12  VFG000434(gi:17233482) (pefC) plasmid-encoded fimbriae usher protein PefC [Pef (VF0104)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
6 gi|15922996|ref|NP_370530.1| DNA gyrase subunit A (SAV0006) [Staphylococcus aureus subsp. aureus Mu50] 889 COG0516 5-834 -209.000 43  [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
H.sapiens 6-205 -23.200 25  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 601-900)
71-383 -54.500 23  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 751-1050)
235-488 -28.300 18  sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Homo sapiens GN=TOP2A PE=1 SV=3 (Range: 901-1200)
HGM_OVER 400-487 -3.290 PB045072 _Gut.Meta.Jp.0111663_ gi|163310555|dbj|BABD01000145.1||3 (+ 1662:2028~0 complete)
JCSG0516 6-812 -199.000 45  TM1084 TM1084 282951 Purified-2001-04-24
NEW_HUMAN_DOMAINS 38-166 -5.280 19  sp|Q9H1B7|I2BPL_HUMAN Interferon regulatory factor 2-binding protein-like OS=Homo sapiens GN=IRF2BPL PE=1 SV=1 (Range: 373-516)
PDB0516 1-503 -146.000 69  4ddq_A mol:protein length:502 DNA gyrase subunit A
31-741 -126.000 37  1zvu_A mol:protein length:716 Topoisomerase IV subunit A
503-817 -67.800 35  3uc1_A mol:protein length:327 DNA gyrase subunit A
PfamA30U 33-473 -61.000 21  PF00521.18; A0A0D1DXS4_USTMA/785-1232; DNA gyrase/topoisomerase IV, subunit A
613-658 -15.300 50  PF03989.11; GYRA_HAEIN/641-686; DNA gyrase C-terminal domain, beta-propeller
SCOP206 31-489 -133.000 56  d3ilwa_ e.11.1.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
503-812 -66.000 35  d4g3na_ b.68.10.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
VFDB 18-702 -8.510 11  VFG000106(gi:15640862) (acfD) accessory colonization factor AcfD [ACF (VF0127)] [Vibrio cholerae O1 biovar El Tor str. N16961]
7 gi|15922997|ref|NP_370531.1| hypothetical protein (SAV0007) [Staphylococcus aureus subsp. aureus Mu50] 276 COG0516 9-276 -79.700 23  [G] KOG3974 Predicted sugar kinase
H.sapiens 1-274 -68.900 20  sp|Q8IW45|CARKD_HUMAN(removed signalp:1-25) Carbohydrate kinase domain-containing protein OS=Homo sapiens GN=CARKD PE=1 SV=1
HGM_OVER 158-273 -3.070 11  PB004996 Q5NNS6_ZYMMO/1-150 PB004996; Pfam-B_4996;
JCSG0516 5-276 -103.000 45  RK10657A NP_815490.1 375213 PDB-2007-08-29
NEW_HUMAN_DOMAINS 57-232 -4.790 12  sp|Q8IY22|CMIP_HUMAN C-Maf-inducing protein OS=Homo sapiens GN=CMIP PE=1 SV=3 (Range: 158-339)
PDB0516 2-276 -99.600 45  2r3b_A mol:protein length:310 YjeF-related protein
PfamA30U 30-269 -80.700 29  PF01256.15; NNRD_BACSU/30-270; Carbohydrate kinase
SCOP206 5-276 -104.000 45  d2r3ba1 c.72.1.0 (A:1-276) automated matches {Enterococcus faecalis [TaxId: 226185]}
VFDB 6-267 -8.810 10  VFG002027(gi:15792474) (hldE) bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase [LOS (VF0326)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
8 gi|161375866|ref|NP_370532.2| histidine ammonia-lyase (SAV0008) [Staphylococcus aureus subsp. aureus Mu50] 504 COG0516 2-503 -135.000 38  [E] COG2986 Histidine ammonia-lyase
H.sapiens 1-188 -60.000 44  sp|P42357|HUTH_HUMAN Histidine ammonia-lyase OS=Homo sapiens GN=HAL PE=1 SV=1 (Range: 1-300)
40-335 -101.000 44  sp|P42357|HUTH_HUMAN Histidine ammonia-lyase OS=Homo sapiens GN=HAL PE=1 SV=1 (Range: 151-450)
189-486 -105.000 47  sp|P42357|HUTH_HUMAN Histidine ammonia-lyase OS=Homo sapiens GN=HAL PE=1 SV=1 (Range: 301-600)
HGM_OVER 52-129 -3.870 11  PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;
JCSG0516 2-442 -5.080 13  TM1719 TM1719 283575 Purified-2004-02-02
NEW_HUMAN_DOMAINS 305-414 -7.290 17  sp|Q9NRJ4|TULP4_HUMAN Tubby-related protein 4 OS=Homo sapiens GN=TULP4 PE=2 SV=2 (Range: 647-767)
PDB0516 2-503 -138.000 38  1b8f_A mol:protein length:509 Histidine ammonia-lyase
PfamA30U 10-471 -130.000 38  PF00221.17; HUTH_IDILO/11-471; Aromatic amino acid lyase
SCOP206 2-503 -138.000 38  d1gkma_ a.127.1.2 (A:) Histidine ammonia-lyase (HAL) {Pseudomonas putida [TaxId: 303]}
VFDB 30-419 -5.020 16  VFG041307(gi:52842182) (pieC/lirE) Dot/Icm type IV secretion system effector PieC/LirE [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
9 gi|15922999|ref|NP_370533.1| seryl-tRNA synthetase (SAV0009) [Staphylococcus aureus subsp. aureus Mu50] 428 COG0516 1-424 -139.000 55  [J] COG0172 Seryl-tRNA synthetase
H.sapiens 1-426 -115.000 30  sp|Q9NP81|SYSM_HUMAN Seryl-tRNA synthetase, mitochondrial OS=Homo sapiens GN=SARS2 PE=1 SV=1
HGM_OVER 261-367 -2.950 15  PB031792 gi|154174791|ref|YP_001409041.1| flavodoxin family protein [Campylobacter curvus 525.92]gi|112804021|gb|EAU01365.1| flavodoxin family protein [Campylobacter curvus 525.92]
JCSG0516 1-419 -136.000 52  TM1379 TM1379 283240 Crystal|NMR-2004-06-10
NEW_HUMAN_DOMAINS 26-108 -5.740 11  tr|B5MDG7|B5MDG7_HUMAN Uncharacterized protein OS=Homo sapiens GN=HMG20B PE=4 SV=2 (Range: 199-286)
PDB0516 1-419 -135.000 52  2dq3_A mol:protein length:425 Seryl-tRNA synthetase
PfamA30U 1-107 -27.700 25  PF02403.20; C5WTV8_SORBI/1-114; Seryl-tRNA synthetase N-terminal domain
SCOP206 1-113 -40.200 23  d1seta1 a.2.7.1 (A:1-110) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
117-427 -111.000 39  d1seta2 d.104.1.1 (A:111-421) Seryl-tRNA synthetase (SerRS) {Thermus thermophilus, strain hb27 [TaxId: 274]}
VFDB 1-250 -12.000 10  VFG045487(gi:52840451) (ravF) Dot/Icm type IV secretion system effector RavF [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
10 gi|15923000|ref|NP_370534.1| hypothetical protein (SAV0010) [Staphylococcus aureus subsp. aureus Mu50] 231 COG0516 2-221 -61.000 22  [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance)
H.sapiens 44-207 -9.170 11  sp|A6NGZ7|U93BL_HUMAN Putative protein unc-93 homolog B1-like protein OS=Homo sapiens PE=5 SV=3
HGM_OVER 22-231 -7.190 PB032242 Q8FLW6_COREF/1-257 PB032242; Pfam-B_32242;
JCSG0516 68-161 -7.010 17  SP17608A YP_975320.1 412340 Selected-2009-11-12
NEW_HUMAN_DOMAINS 26-138 -6.270 15  sp|Q8N5W9|F101B_HUMAN Protein FAM101B OS=Homo sapiens GN=FAM101B PE=1 SV=1 (Range: 80-214)
PDB0516 25-97 -7.410 11  3cwb_G mol:protein length:81 MITOCHONDRIAL UBIQUINOL-CYTOCHROME C REDUCTAS
PfamA30U 16-156 -76.800 30  PF03591.12; I0I5R9_CALAS/20-162; AzlC protein
23-225 -10.900 12  PF05297.9; LMP1_EBVB9/1-386; Herpesvirus latent membrane protein 1 (LMP1)
SCOP206 25-95 -6.600 d2a06g_ f.23.13.1 (G:) Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) {Cow (Bos taurus) [TaxId: 9913]}
VFDB 26-174 -4.910 12  VFG000263(gi:15676371) (tbpB) transferrin-binding protein B [Tbp (VF0046)] [Neisseria meningitidis MC58]
11 gi|15923001|ref|NP_370535.1|(removed signalp:1-29) hypothetical protein (SAV0011) [Staphylococcus aureus subsp. aureus Mu50] 80 COG0516 1-80 -45.100 16  [S] COG4392 Predicted membrane protein
H.sapiens 19-79 -9.110 sp|Q4V9L6|TM119_HUMAN(removed signalp:1-25) Transmembrane protein 119 OS=Homo sapiens GN=TMEM119 PE=2 SV=1
HGM_OVER 3-80 -5.780 10  PB006154 _JGI.0331794_ 2004021056 [Human Gut Community Subject 7]
JCSG0516 52-80 -6.410 10  SP19357A YP_002937542.1 411112 Purified-2010-09-29
NEW_HUMAN_DOMAINS 6-63 -5.080 10  sp|Q96RY5|CRML_HUMAN Protein cramped-like OS=Homo sapiens GN=CRAMP1L PE=1 SV=3 (Range: 1172-1241)
PDB0516 62-80 -5.930 10  2knc_A mol:protein length:54 Integrin alpha-IIb
PfamA30U 1-76 -11.600 14  PF05437.10; Q8NTP7_CORGL/8-105; Branched-chain amino acid transport protein (AzlD)
SCOP206 1-26 -5.360 19  d1p8ba_ g.3.6.4 (A:) Pab1, subunit b {Pea (Pisum sativum) [TaxId: 3888]}
VFDB 9-61 -5.500 VFG000669(gi:24111747) (gtrA) bactoprenol-linked glucose translocase/flippase [LPS (VF0124)] [Shigella flexneri 2a str. 301]
12 gi|15923002|ref|NP_370536.1| putative homoserine-o-acetyltransferase (SAV0012) [Staphylococcus aureus subsp. aureus Mu50] 329 COG0516 4-325 -100.000 28  [E] COG2021 Homoserine acetyltransferase
H.sapiens 28-329 -25.200 11  sp|Q9BV23|ABHD6_HUMAN(removed signalp:1-34) Monoacylglycerol lipase ABHD6 OS=Homo sapiens GN=ABHD6 PE=2 SV=1
HGM_OVER 107-240 -3.310 HGC00789 gi|163310627|dbj|BABD01000073.1|7.0 TMP01036;
JCSG0516 28-329 -26.700 16  SP4101A YP_001714613.1 406330 PDB-2014-02-05
NEW_HUMAN_DOMAINS 59-93 -4.760 sp|Q8N8Q8|COX18_HUMAN Mitochondrial inner membrane protein COX18 OS=Homo sapiens GN=COX18 PE=2 SV=1 (Range: 1-81)
PDB0516 8-329 -132.000 99  4qlo_A mol:protein length:360 homoserine O-acetyltransferase
PfamA30U 31-324 -21.800 PF03096.12; NDRG2_HUMAN/40-318; Ndr family
SCOP206 5-323 -106.000 29  d2vata1 c.69.1.40 (A:7-382) Acetyl-CoA:deacetylcephalosporin C acetyltransferase CefG {Acremonium chrysogenum [TaxId: 5044]}
VFDB 28-329 -26.000 14  VFG000156(gi:15598675) (rhlA) rhamnosyltransferase chain A [Rhamnolipid (VF0089)] [Pseudomonas aeruginosa PAO1]
13 gi|15923003|ref|NP_370537.1| hypothetical protein (SAV0013) [Staphylococcus aureus subsp. aureus Mu50] 331 COG0516 25-330 -87.500 19  [S] COG4241 Predicted membrane protein
H.sapiens 54-249 -9.960 12  sp|Q8NC44|F134A_HUMAN Protein FAM134A OS=Homo sapiens GN=FAM134A PE=1 SV=3
161-315 -10.200 13  sp|P40145|ADCY8_HUMAN Adenylate cyclase type 8 OS=Homo sapiens GN=ADCY8 PE=1 SV=1 (Range: 1-300)
HGM_OVER 225-302 -3.730 10  PB006205 Q3F123_BACTI/1-181 PB006205; Pfam-B_6205;
JCSG0516 115-184 -8.780 SP2485D NP_371294.1 413704 Crystal|NMR-2012-02-26
NEW_HUMAN_DOMAINS 265-315 -4.910 17  sp|Q9HAT1|LMA1L_HUMAN Protein ERGIC-53-like OS=Homo sapiens GN=LMAN1L PE=2 SV=2 (Range: 460-526)
PDB0516 19-146 -8.760 14  3rlb_A mol:protein length:192 ThiT
PfamA30U 38-317 -75.600 23  PF09991.7; U5LGL3_9BACI/15-301; Predicted membrane protein (DUF2232 topsan)
SCOP206 136-194 -3.670 d2wbma2 a.5.8.0 (A:88-162) automated matches {Methanothermobacter thermautotrophicus [TaxId: 187420]}
VFDB 33-225 -5.750 12  VFG001850(gi:52842892) (dotA) Dot/Icm type IV secretion system protein DotA [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
14 gi|15923004|ref|NP_370538.1|(removed signalp:1-32) hypothetical protein (SAV0014) [Staphylococcus aureus subsp. aureus Mu50] 623 COG0516 2-623 -142.000 50  [T] COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain
H.sapiens 290-572 -11.800 11  sp|Q8WUY3|PRUN2_HUMAN Protein prune homolog 2 OS=Homo sapiens GN=PRUNE2 PE=1 SV=3 (Range: 1-300)
290-623 -10.700 14  sp|Q86TP1|PRUNE_HUMAN Protein prune homolog OS=Homo sapiens GN=PRUNE PE=1 SV=2
HGM_OVER 469-525 -4.690 PB009661 _Gut.Meta.Jp.0000785_ gi|162567239|dbj|BAAU01000237.1||2 (- 3549:4008~0 complete)
JCSG0516 294-623 -38.100 20  TM1595 TM1595 283452 Purified-2001-12-11
NEW_HUMAN_DOMAINS 383-438 -6.040 21  sp|Q9ULD2|MTUS1_HUMAN Microtubule-associated tumor suppressor 1 OS=Homo sapiens GN=MTUS1 PE=1 SV=2 (Range: 51-110)
PDB0516 23-127 -28.400 29  2m1c_A mol:protein length:113 DHH subfamily 1 protein
122-268 -9.600 18  4zve_A mol:protein length:172 Diguanylate cyclase DosC
238-622 -11.200 12  2zxo_A mol:protein length:666 Single-stranded DNA specific exonuclease RecJ
281-623 -36.100 20  5cet_A mol:protein length:341 Bifunctional oligoribonuclease and PAP phosph
PfamA30U 127-268 -7.880 14  PF05165.10; GCH3_METTH/1-249; GTP cyclohydrolase III
SCOP206 293-621 -11.200 13  d1ir6a_ c.107.1.2 (A:) Exonuclease RecJ {Thermus thermophilus [TaxId: 274]}
304-505 -19.800 21  d1wpna_ c.107.1.1 (A:) Manganese-dependent inorganic pyrophosphatase (family II) {Bacillus subtilis [TaxId: 1423]}
VFDB 46-545 -10.300 12  VFG045467(gi:53718898) (cdpA) cyclic di-GMP phosphodiesterase [CdpA (VF0432)] [Burkholderia pseudomallei K96243]
15 gi|15923005|ref|NP_370539.1| 50S ribosomal protein L9 (SAV0015) [Staphylococcus aureus subsp. aureus Mu50] 148 COG0516 1-147 -72.400 32  [J] COG0359 Ribosomal protein L9
H.sapiens 1-148 -46.300 21  sp|Q9BYD2|RM09_HUMAN 39S ribosomal protein L9, mitochondrial OS=Homo sapiens GN=MRPL9 PE=1 SV=2
HGM_OVER 25-148 -3.340 14  HGC00044 gi|162658718|dbj|BAAX01000887.1|1.0 TMP00920;
JCSG0516 1-148 -84.200 35  TM0863 TM0863 282733 Purified-2001-04-19
NEW_HUMAN_DOMAINS 79-144 -6.780 18  sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 OS=Homo sapiens GN=LRP2 PE=1 SV=3 (Range: 4472-4553)
PDB0516 1-148 -85.900 59  1div_A mol:protein length:149 RIBOSOMAL PROTEIN L9
PfamA30U 1-47 -31.600 57  PF01281.17; RL9_FERNB/1-47; Ribosomal protein L9, N-terminal domain
63-147 -46.700 34  PF03948.12; R7G1M1_9FIRM/63-146; Ribosomal protein L9, C-terminal domain
SCOP206 1-52 -33.700 69  d2hbaa1 d.100.1.1 (A:1-52) Ribosomal protein L9 N-domain {Bacillus stearothermophilus [TaxId: 1422]}
56-148 -52.600 54  d1diva1 d.99.1.1 (A:56-149) Ribosomal protein L9 C-domain {Bacillus stearothermophilus [TaxId: 1422]}
VFDB 19-108 -6.040 VFG043404(gi:218563066) (flgJ) flagellar rod assembly protein/muramidase FlgJ [Pse5Ac7Ac, Pse5Ac7Am, Pse8OAc, Pse5Am7AcGlnAc (AI151)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
16 gi|15923006|ref|NP_370540.1| replicative DNA helicase (SAV0016) [Staphylococcus aureus subsp. aureus Mu50] 466 COG0516 2-464 -135.000 42  [L] COG0305 Replicative DNA helicase
H.sapiens 11-253 -11.800 14  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1 (Range: 151-450)
114-446 -44.600 18  sp|Q96RR1|PEO1_HUMAN(removed signalp:1-19) Twinkle protein, mitochondrial OS=Homo sapiens GN=PEO1 PE=1 SV=1 (Range: 301-600)
HGM_OVER 227-411 -2.510 15  PB025553 _HOMD.0078651_ pint_c_1_4510 Prevotella intermedia 17 [1755134 - 1755736] ORF
JCSG0516 8-462 -140.000 45  TM1736 TM1736 283591 Purified-2001-11-28
NEW_HUMAN_DOMAINS 315-409 -5.220 16  sp|O43933|PEX1_HUMAN Peroxisome biogenesis factor 1 OS=Homo sapiens GN=PEX1 PE=1 SV=1 (Range: 236-331)
PDB0516 1-464 -144.000 59  2r6a_A mol:protein length:454 Replicative helicase
PfamA30U 9-111 -49.900 37  PF00772.19; Q1MZU6_9GAMM/10-112; DnaB-like helicase N terminal domain
185-457 -106.000 58  PF03796.13; M4NCG5_9GAMM/198-453; DnaB-like helicase C terminal domain
SCOP206 10-111 -49.800 43  d1b79a_ a.81.1.1 (A:) N-terminal domain of DnaB helicase {Escherichia coli [TaxId: 562]}
169-460 -57.600 16  d1cr1a_ c.37.1.11 (A:) Gene 4 protein (g4p, DNA primase), helicase domain {Bacteriophage T7 [TaxId: 10760]}
VFDB 90-396 -5.720 15  VFG002521(gi:53720903) (flhF) flagellar biosynthesis regulator FlhF [Flagella (VF0430)] [Burkholderia pseudomallei K96243]
17 gi|15923007|ref|NP_370541.1| adenylosuccinate synthetase (SAV0017) [Staphylococcus aureus subsp. aureus Mu50] 427 COG0516 1-427 -150.000 65  [F] COG0104 Adenylosuccinate synthase
H.sapiens 1-423 -141.000 40  sp|Q8N142|PURA1_HUMAN Adenylosuccinate synthetase isozyme 1 OS=Homo sapiens GN=ADSSL1 PE=1 SV=1
HGM_OVER 306-401 -2.110 14  HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;
JCSG0516 3-423 -128.000 39  TM1096 TM1096 282962 Purified-2001-10-30
NEW_HUMAN_DOMAINS 229-310 -6.170 16  tr|F5H3N1|F5H3N1_HUMAN Uncharacterized protein OS=Homo sapiens GN=KIAA0528 PE=4 SV=1 (Range: 135-209)
PDB0516 1-427 -150.000 71  4m0g_A mol:protein length:432 Adenylosuccinate synthetase
PfamA30U 4-421 -138.000 40  PF00709.19; S3D6Z3_GLAL2/4-421; Adenylosuccinate synthetase
SCOP206 2-427 -146.000 46  d3hida_ c.37.1.10 (A:) automated matches {Yersinia pestis [TaxId: 214092]}
VFDB 1-402 -4.860 12  VFG001375(gi:15900288) (cps4K) capsular polysaccharide biosynthesis protein Cps4K [Capsule (VF0144)] [Streptococcus pneumoniae TIGR4]
18 gi|15923008|ref|NP_370542.1| response regulator (SAV0018) [Staphylococcus aureus subsp. aureus Mu50] 235 COG0516 3-231 -85.900 37  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
H.sapiens 5-166 -43.600 14  sp|O95263|PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2 (Range: 1-300)
5-210 -22.300 15  sp|O60658|PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8A OS=Homo sapiens GN=PDE8A PE=1 SV=2 (Range: 1-300)
HGM_OVER 61-139 -3.980 13  PB039305 _Gut.Meta.Jp.0057508_ gi|162726131|dbj|BAAY01002830.1||2 (- 1092:1581~0 complete)
JCSG0516 3-235 -116.000 50  TM1655 TM1655 283512 Selected-2001-10-12
NEW_HUMAN_DOMAINS 6-135 -29.500 13  sp|Q9NX45|SOLH2_HUMAN Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 OS=Homo sapiens GN=SOHLH2 PE=2 SV=2 (Range: 1-196)
PDB0516 2-233 -115.000 46  2oqr_A mol:protein length:230 Sensory transduction protein regX3
PfamA30U 7-112 -54.500 25  PF00072.22; RSSB_ECOLI/10-121; Response regulator receiver domain
155-231 -34.100 31  PF00486.26; I0DPC2_PROSM/145-220; Transcriptional regulatory protein, C terminal
SCOP206 4-124 -70.300 30  d2qzja_ c.23.1.0 (A:) automated matches {Clostridium difficile [TaxId: 272563]}
137-235 -57.900 78  d2hwva1 a.4.6.0 (A:134-232) automated matches {Enterococcus faecalis [TaxId: 226185]}
VFDB 6-235 -85.900 39  VFG001386(gi:15607897) (phoP) Possible two component system response transcriptional positive regulator PhoP [PhoP (VF0286)] [Mycobacterium tuberculosis H37Rv]
19 gi|15923009|ref|NP_370543.1| two-component sensor histidine kinase (SAV0019) [Staphylococcus aureus subsp. aureus Mu50] 608 COG0516 1-608 -141.000 45  [T] COG5002 Signal transduction histidine kinase
H.sapiens 236-435 -14.300 15  sp|O60658|PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3`,5`-cyclic phosphodiesterase 8A OS=Homo sapiens GN=PDE8A PE=1 SV=2 (Range: 151-450)
361-603 -26.400 14  sp|Q5CZC0|FSIP2_HUMAN Fibrous sheath-interacting protein 2 OS=Homo sapiens GN=FSIP2 PE=1 SV=4 (Range: 4201-4500)
HGM_OVER 241-569 -3.130 PB001934 Q6PSL5_CHLRE/821-1150 PB001934; Pfam-B_1934;
JCSG0516 2-605 -62.600 14  TT16453A SBAL_17SEP04_CONTIG201_REVISED_GENE1177 404250 Selected-2009-08-14
116-608 -101.000 22  TM0853 TM0853 282723 Purified-2001-07-16
NEW_HUMAN_DOMAINS 360-507 -5.520 10  sp|Q9P278|FNIP2_HUMAN Folliculin-interacting protein 2 OS=Homo sapiens GN=FNIP2 PE=1 SV=2 (Range: 312-450)
PDB0516 31-182 -28.200 97  4ywz_A mol:protein length:152 Sensor protein kinase WalK
119-255 -30.600 12  4gyc_B mol:protein length:135 Sensory rhodopsin II transducer
170-608 -110.000 39  4i5s_A mol:protein length:450 Putative histidine kinase CovS; VicK-like pro
PfamA30U 1-182 -13.500 13  PF10144.7; SMP_YERPE/1-162; Bacterial virulence factor haemolysin
184-250 -14.600 19  PF00672.23; P95626_RHILE/179-249; HAMP domain
265-367 -13.100 PF13596.4; C1CZ44_DEIDV/745-850; PAS domain
376-442 -22.000 29  PF00512.23; Q55783_SYNY3/185-253; His Kinase A (phospho-acceptor) domain
393-588 -14.700 12  PF10090.7; V5SF53_9RHIZ/32-212; Histidine phosphotransferase
486-598 -47.900 35  PF02518.24; O52937_9CYAN/626-739; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
SCOP206 205-255 -11.200 33  d2y0ta_ a.274.1.1 (A:) automated matches {Archaeoglobus fulgidus [TaxId: 2234]}
248-367 -14.100 14  d1ew0a_ d.110.3.2 (A:) Histidine kinase FixL heme domain {Rhizobium meliloti [TaxId: 382]}
358-444 -45.100 29  d2c2aa1 a.30.2.1 (A:232-320) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}
445-600 -58.900 37  d2c2aa2 d.122.1.3 (A:321-481) Sensor histidine kinase TM0853 {Thermotoga maritima [TaxId: 2336]}
VFDB 9-605 -66.800 21  VFG009810(gi:15607898) (phoR) Possible two component system response sensor kinase membrane associated PhoR [PhoP/R (CVF331)] [Mycobacterium tuberculosis H37Rv]
20 gi|15923010|ref|NP_370544.1| hypothetical protein (SAV0020) [Staphylococcus aureus subsp. aureus Mu50] 453 COG0516 11-453 -105.000 16  [S] COG4863 Uncharacterized protein conserved in bacteria
H.sapiens 2-74 -8.000 sp|P04921|GLPC_HUMAN Glycophorin-C OS=Homo sapiens GN=GYPC PE=1 SV=1
HGM_OVER 1-71 -6.650 HGC01179 gi|162738527|dbj|BAAZ01025469.1|2.0 TMP01658;
JCSG0516 11-448 -32.100 14  SP16933A ZP_02036918.1 407246 Purified-2010-09-29
NEW_HUMAN_DOMAINS 2-37 -6.160 16  sp|O75949|F155B_HUMAN Transmembrane protein FAM155B OS=Homo sapiens GN=FAM155B PE=2 SV=2 (Range: 1-66)
PDB0516 49-453 -86.500 15  2fgt_A mol:protein length:417 Two-component system yycF/yycG regulatory pro
PfamA30U 14-453 -94.700 21  PF07435.9; Q8YA70_LISMO/5-440; YycH protein
SCOP206 1-31 -6.360 29  d3dind_ f.23.28.1 (D:) Preprotein translocase SecE subunit {Thermotoga maritima MSB8 [TaxId: 243274]}
VFDB 1-102 -8.120 10  VFG036884(gi:15676785) (pilK) pilin-like protein may involving in pseudopilus formation [Type IV pili (CVF189)] [Neisseria meningitidis MC58]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ye Y, Godzik A. FATCAT: a web server for flexible structure comparison and structure similarity searching. Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W582-5.