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Welcome from
This is version 1.20 of the Surface Entropy Reduction prediction (SERp) server from January 2007. This exploratory tool aims to aid identification of sites that are most suitable for mutation designed to enhance crystallizability by a Surface Entropy Reduction approach. More Info: introduction page, publication reference.

Please send bug reports, questions and feedback to adminstrator <>. To submit multiple sequences in FASTA format, use the Batch Submission page.

Sequence Name: [?]
Email Address: [?]
Results Delivery: Link to Website Email inline Email attached [?]

Protein or DNA sequence: [?]

Starting Position: (residue or nucleotide)

Also submit this job to XtalPred for analysis (you will get results separately).

SER successes gallery -- highlights structures that have been solved using surface entropy reduction.

PDB Structure: 3DLK.
Click here to access the entire gallery.